1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with adenosine diphosphate in 299 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (adenosine diphosphate) | Trials (adenosine diphosphate) | Recent Studies (post-2010) (adenosine diphosphate) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 23,989 | 498 | 3,114 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | adenosine diphosphate (IC50) |
|---|---|---|---|
| Chain A, Kinesin-like protein KIF11 | Homo sapiens (human) | 0.45 | |
| Heat shock 70 kDa protein 1A | Homo sapiens (human) | 0.5 | |
| Sensor protein kinase WalK | Staphylococcus aureus | 7.189 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 130 (43.48) | 18.7374 |
| 1990's | 118 (39.46) | 18.2507 |
| 2000's | 33 (11.04) | 29.6817 |
| 2010's | 15 (5.02) | 24.3611 |
| 2020's | 3 (1.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colwell, JA; Halushka, PV; Nair, RM; Rogers, C; Sagel, J; Whetsell, A | 1 |
| Feuerstein, G; Friedman, E; Gleason, MM; Gu, JL; Powers, DA; Sarau, HM; Stadel, JM; Wang, HY; Yue, TL | 1 |
| Cattaneo, M; Lecchi, A; Mannucci, PM; McGregor, JL; Randi, AM | 1 |
| Selak, MA | 1 |
| Bochkov, VN; Fuki, IV; Lyakishev, AA; Matchin, YG; Tkachuk, VA | 1 |
| Akkerman, JW; Burgers, JA | 2 |
| Clarkson, WD; Heemskerk, JW; Sage, SO; Sargeant, P | 1 |
| Crook, P; May, GR; Moore, PK; Page, CP | 1 |
| Feuerstein, G; Lynch, KM; Ohlstein, EH; Poyser, R; Rabinovici, R; Sellers, TS; Slivjak, MJ; Smith, EF; Sulpizio, A; Yue, TL | 1 |
| Karaulov, AV; Melkova, OM; Porodenko, NV; Prokudin, VIu | 1 |
| Ko, FN; Lin, CN; Liou, SS; Teng, CM | 1 |
| Anfossi, G; Burzacca, S; Cavalot, F; De Facis, R; Lucchina, PG; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M | 1 |
| Bond, SE; Dillingham, EO; Gollamudi, R; Lawrence, WH; Lyman, BA | 1 |
| Ekholm, J; Hanahan, DJ; Nouchi, T; Tatsumi, Y | 1 |
| Tatarintsev, AV; Varfolomeyev, SD; Vrzheshch, PV; Yershov, DE | 1 |
| Huang, SC; Huang, TF; Li, HL; Teng, CM; Wu, TS | 1 |
| Misso, NL; Thompson, PJ | 1 |
| Bin, Z; Kun, L | 1 |
| Devyatova, O; Hollister, AS; Menshikov, M | 1 |
| He, Y; Hon, PM; Jiang, LM; Lee, CM; Shang, HS; Wong, HN | 1 |
| Ammit, AJ; O'Neill, C | 1 |
| Höche, D; Hochhaus, A; Mindner, K; Ostermann, G | 1 |
| Donas, A; Droudes, C; Evangelou, A; Tselepis, AD; Tsoukatos, D | 1 |
| Alonso, MT; Alvarez, J; García-Sancho, J; Montero, M; Sanchez, A | 1 |
| Baldo, BA; Cooney, SJ; Smal, MA | 1 |
| Klee, A; Schmid-Schönbein, GW; Seiffge, D | 1 |
| Birke, FW; Ensinger, HA | 1 |
| Akkerman, JW; van Willigen, G | 1 |
| Betteridge, KJ; Croy, BA; Johnstone, IB; Rieger, D; Scodras, JM | 1 |
| Jayson, MI; Klimiuk, PS; Price, JE | 1 |
| Bellinger, OK; Breddin, HK; Kirchmaier, CM; Schulz, B | 1 |
| Capecchi, PL; Ceccatelli, L; Di Perri, T; Gistri, A; Laghi Pasini, F; Mazza, S; Pasqui, AL | 1 |
| Takahashi, O | 1 |
| Ahmed, Y; Elder, MG; Sullivan, MH | 1 |
| Crane, S; Johnstone, IB; Viel, L; Whiting, T | 1 |
| Kosugi, T; Minei, S; Nakamura, M; Noguchi, S; Saitoh, S; Shimoji, T | 1 |
| Glusa, E | 1 |
| Krugliak, J; Marx, G; Shaklai, M | 1 |
| Kinjoh, K; Kosugi, T; Nakamura, M; Saitoh, S | 1 |
| Gilani, AH; Husnain, SQ; Saeed, SA; Suria, A | 1 |
| Hofmann, B; Kertscher, HP; Ostermann, G; Till, U | 1 |
| Dangelmaier, C; Selak, M; Smith, JB | 1 |
| Akada, S; Hisanaga, H; Ichijo, M; Iioka, H; Morimoto, K; Moriyama, I | 1 |
| Bochkov, VN; Bochkova, NA; Kukharchuk, VV; Lyakishev, AA; Rozhkova, TA; Tkachuk, VA | 1 |
| Kakishita, E; Nagai, K; Oura, Y; Suehiro, A | 1 |
| Ezaki, M; Inoue, Y; Miwa, M; Nakamura, K; Tomita, T | 1 |
| Jobson, TM; Rink, TJ; Sage, SO | 1 |
| Kambayashi, J; Kawasaki, T; Mori, T; Sakon, M; Shiba, E; Uemura, Y | 1 |
| Gilani, AH; Saeed, SA | 1 |
| Champeix, P; Favier, R; Hurtaud, MF; Kaplan, C; Lecompte, T; Morel, MC; Potevin, F; Samama, M; Schlegel, N | 1 |
| Butler, KD; Herd, CM; May, GR; Page, CP | 1 |
| Anfossi, G; Cavalot, F; Emanuelli, G; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M | 1 |
| Bazzoni, G; Bertelé, V; Del Maschio, A; Prosdocimi, M; Zatta, A | 1 |
| Huang, TF; Ko, FN; Liu, YM; Sheu, SJ; Teng, CM | 1 |
| Halenda, SP; Rehm, AG | 1 |
| Beilin, LJ; Croft, KD; Masarei, J; Rouse, I; Vandongen, R | 1 |
| Csanda, E; Filep, J; Hermán, F; Jelencsik, I; Kovács, K; Magyar, K | 1 |
| Battistini, B; Filep, JG; Hermán, F; Sirois, P | 1 |
| Fenton, JW; Kaplan, JE; Krasodomski, JA; Moon, DG; Morton, KD; van der Zee, H | 1 |
| Bourgain, RH | 1 |
| Hayasaki, Y; Honma, Y; Kakushi, H; Kawasumi, K; Matsubara, T; Shike, T; Takeuchi, Y; Uchida, K | 1 |
| Hallam, TJ; Rink, TJ | 1 |
| Pipili, E | 1 |
| Benveniste, J; Chignard, M; Coëffier, E | 1 |
| Keery, RJ; Lumley, P | 1 |
| Bevan, J; Heptinstall, S | 1 |
| Bielawiec, M; Bodzenta-Lukaszyk, A; Dabrowski, S; Krupiński, K | 1 |
| Avdonin, PV; Bochkov, VN; Cheglakov, IB; Tkachuk, VA | 1 |
| Ito, Y; Kametani, F; Kitagawa, S; Oda, Y | 1 |
| Astrina, OS; Lomazova, KD; Poliakova, AM; Tsukerman, DB | 1 |
| Bompiani, GD; Cardella, F; Davì, G; Giardina, E; Meli, F; Strano, A; Triolo, G | 1 |
| Ershov, DE; Fedorov, NA; Tatarintsev, AV; Varfolomeev, SD; Vrzheshch, PV; Zaĭtsev, SV | 1 |
| Benveniste, J; Bouloux, C; Chignard, M; Delautier, D; Lalau Keraly, C; Motte, G; Sebag, C | 1 |
| Bryant, NL; Guccione, MA; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA | 1 |
| Cassaro, CM; Chamone, DA; Maeda, NY; Sampaio, CA; Sampaio, MU | 1 |
| Bielawiec, M; Bodzenta-Lukaszyk, A; Gabryelewicz, A; Lukaszyk, A | 1 |
| Bevan, J; Glusa, E; Heptinstall, S | 1 |
| Budzynski, A; Scrutton, MC; Shattil, SJ | 1 |
| Alonso, MT; García-Sancho, J; Sanchez, A | 2 |
| Gerrard, JM; MacIntyre, DE; McNicol, A | 1 |
| Bondy, GS; Gentry, PA | 1 |
| Gentry, PA; Liptrap, RM; Niemuller, C; Ross, ML | 1 |
| de Almeida, PJ; Pires, JG | 1 |
| Kendrew, PJ; Nidorf, SM; Strophair, J; Sturm, M; Taylor, RR | 1 |
| Gabassov, VA; Gavrilov, IIu; Markosian, RA; Popov, EG; Pozin, EIa | 1 |
| Antunes, E; Prado-Franceschi, J | 1 |
| Herd, C; Morley, J; Sanjar, S; Smith, D | 1 |
| Frojmovic, M; Pedvis, L; Wong, T | 1 |
| Gabbasov, ZA; Naumov, VG; Okur, FM; Popov, EG; Skvortsov, AA | 1 |
| Ioannoni, B; McCormack, JG; Seow, WK; Teh, BS; Thong, YH | 1 |
| Beilin, LJ; Kendrew, PJ; Strophair, JM; Sturm, MJ; Taylor, RR; Vandongen, R | 1 |
| Anfossi, G; Cavalot, F; Emanuelli, G; Massucco, P; Mularoni, E; Trovati, M | 1 |
| Avdonin, PV; Kravchenko, AN; Men'shikov, MIu; Nekrasova, AA; Shkhvatsabaia, IK | 1 |
| Abbondanza, M; Benedetto, C; Bertini, E; Enrieu, N; Massobrio, M; Tetta, C | 1 |
| Asyee, GM; Schaap, MC; Sturk, A; ten Cate, JW; van Maanen, M | 1 |
| Ambler, J; Birch, J; Maguire, ED; Wallis, RB | 1 |
| Bühler, FR; Dimitrov, D; Resink, TJ; Stucki, S | 1 |
| Bush, LR; Smith, SG | 1 |
| Kumahara, Y; Masugi, F; Oda, M; Ogihara, T; Saeki, S; Saito, K; Sakaguchi, K; Satouchi, K; Tokunaga, K | 1 |
| Atakhanov, ShE; Iurenev, AP; Mazaev, AV; Men'shikov, MIu; Tkhostov, EB | 1 |
| Hardisty, RM; Pannocchia, A | 1 |
| Armstrong, RA; Jones, RL; Wilson, NH | 1 |
| Darius, H; Lefer, AM; Smith, JB | 1 |
| Buxton, DB; Fisher, RA; Hanahan, DJ; Olson, MS | 1 |
| Bushfield, M; MacIntyre, DE; MacMillan, LJ; McNicol, A; Pollock, WK; Shaw, AM | 1 |
| Hallam, TJ; O'Connor, N; Rink, TJ; Simpson, AW | 1 |
| Hatzfeld, A; Hatzfeld, J; Levesque, JP | 1 |
| Bushfield, M; MacIntyre, DE; MacMillan, LJ; McNicol, A; Moffat, KJ; Murdoch, FA; Rossi, AG; Thomson, A | 1 |
| Fuse, I; Hanano, M; Hattori, A; Higashihara, M; Koike, T; Nagayama, R; Shibata, A; Takahashi, H; Takeshige, T; Takizawa, S | 1 |
| Ando, T; Aoki, H; Iwami, M; Kohsaka, M; Nishikawa, M; Okamoto, M; Yoshida, K | 1 |
| Valone, FH | 1 |
| Inoue, K; Kohayakawa, M | 1 |
| Benveniste, J; Braquet, P; Chignard, M; Korth, R; Le Couedic, JP; Norel, X; Nunez, D; Spinnewyn, B | 1 |
| Frölich, JC; Küster, LJ | 1 |
| Aurousseau, M; Benveniste, J; Chignard, M; Greiss, M; Lalau Keraly, C; Maamer, M | 1 |
| Akkerman, JW; Kloprogge, E | 1 |
| Joseph, S; Kakkar, VV; Krishnamurthi, S | 1 |
| Esterbauer, H; Hurst, JS; Juergens, G; Lang, J; Slater, TF; Zollner, H | 1 |
| Chen, WY; Ko, WC; Ouyang, CH; Teng, CM | 1 |
| Aarhus, LL; Shimokawa, H; Vanhoutte, PM | 1 |
| Adnot, S; Joseph, D; Vargaftig, BB | 1 |
| Bell, RM; Greenberg, CS; Hannun, YA | 1 |
| Hayashi, Y; Hirasawa, N; Ohuchi, K; Sugidachi, A; Tsurufuji, S; Watanabe, M | 1 |
| Rink, TJ; Sage, SO | 1 |
| Fraser Mustard, J; Kinlough-Rathbone, RL; Packham, MA; Rand, ML | 1 |
| Bimmler, M; Donath, E; Egger, M; Glaser, R; Spangenberg, P; Till, U | 1 |
| Dejana, E; Fuster, V; Lapetina, E; Moncada, S; Mustard, JF; Tans, G; Vargaftig, BB; Verstraete, M | 1 |
| Choudhury, S; Mookerjea, S; Nagpurkar, A; Randell, E | 1 |
| Handley, DA; Houlihan, WJ; Melden, MK; Saunders, RN; Van Valen, RG | 1 |
| Bugriĭ, EM; Karpov, IuA; Kiktev, VG; Kuz'min, AV; Men'shikov, MIu | 1 |
| Des Prez, RM; Gates, C; King, LE; Rees, RS; Timmons, S | 1 |
| de Almeida, PJ; Marquezini, AJ; Pires, JG | 1 |
| Harada, M; Matsumoto, M; Miwa, M; Suzuki, Y | 1 |
| Andrikopoulos, NK; Demopoulos, CA; Stathopoulou-Sparou, R | 1 |
| Imaizumi, T; Kawamura, Y; Mizono, S; Satoh, K; Shoji, B; Takamatsu, M; Takamatsu, S; Yoshida, H | 1 |
| Aursudkij, B; Barnes, PJ; Chung, KF; Dent, G; Evans, TW; Rogers, DF | 1 |
| Beilin, LJ; Strophair, J; Sturm, M; Taylor, RR; Vandongen, R | 1 |
| Barbanti, M; Bianchini, P; Mastacchi, R; Osima, B | 1 |
| Birch, J; Martin, JF; Milner, PC; Szczeklik, A; Watkins, J | 1 |
| Lapetina, EG; Siess, W | 1 |
| Page, CP; Robertson, DN | 1 |
| Cerletti, C; de Gaetano, G; Lauri, D | 1 |
| Kakkar, VV; Poll, C; Scully, MF; Westwick, J | 1 |
| Honey, AC; Lad, N; Tuffin, DP | 1 |
| Gengenbach, S; Scheid, P; Siffert, W | 1 |
| Gratsianskiĭ, NA; Men'shikov, MIu; Panchenko, EP; Shalaev, SV; Tkachuk, VA | 1 |
| Al-Lamee, KG; Bamford, CH; Middleton, IP | 1 |
| Andries, R; Bourgain, RH; Maes, L; Wu, JX | 1 |
| de Gaetano, G; Dejana, E; Finesso, M; Gorio, A; Languino, LR; Prosdocimi, M; Tessari, F | 1 |
| Houston, DS; Vanhoutte, PM | 1 |
| Lefort, J; Lellouch-Tubiana, A; Pfister, A; Pirotzky, E; Vargaftig, BB | 1 |
| Benveniste, J; Billerey, M; Buonocore, M; Chignard, M; Driss, F; Juhan-Vague, I; Poisson, C; Roul, C; Vague, P | 1 |
| Ma, YH; Ouyang, CH; Teng, CM | 1 |
| Brooks, DP; Chesney, CM; Crofton, JT; Huch, KM; Pifer, DD; Share, L | 1 |
| Andries, R; Bourgain, RH; Braquet, M; Braquet, P; Maes, L; Touqui, L | 1 |
| Altman, R; Rouvier, J; Weisenberger, H | 1 |
| Landolfi, R; Motola, NC; Steiner, M; Turcotte, JG | 1 |
| Giles, TD; Given, MB; Sander, GE | 1 |
| Chesney, CM; Huch, KM; Pifer, DD | 1 |
| Baird, A; Chamberlain, PD; Nunn, B | 1 |
| Kakkar, VV; Krishnamurthi, S; Westwick, J | 1 |
| Benveniste, J; Hadji, L; Mencia-Huerta, JM | 1 |
| Ehrlich, YH; Kornecki, E; Lenox, RH | 1 |
| Haslam, RJ; Vanderwel, M | 1 |
| Benveniste, J; Fouque, F; Joseph, D; Odiot, J; Vargaftig, BB | 1 |
| Bussolino, F; Camussi, G | 1 |
| Rao, GH; Reddy, KR; Schmid, HH; White, JG | 1 |
| Acharya, SB; MacIntyre, DE | 1 |
| Inada, Y; Nishikawa, K; Nomura, H; Terashita, Z; Tsushima, S; Yoshioka, Y | 1 |
| Lee, TC; Malone, B; Snyder, F | 1 |
| Ostermann, G; Thielmann, K; Till, U | 1 |
| Guccione, MA; Kinlough-Rathbone, RL; Mustard, JF; Nina, M; Packham, MA | 1 |
| Broekman, MJ; Kaplan, KL; Marcus, AJ; Safier, LB; Ullman, HL; Weksler, BB; Wong, KT | 1 |
| Heinrich, J; Zimmermann, RE | 1 |
| Bendixen, G; Bendtzen, K; Oxholm, P; Winther, K | 1 |
| Nunn, B | 1 |
| Lüthje, J; Ogilvie, A | 1 |
| Benveniste, J; Chignard, M; Delabassee, D; Delautier, D; Lalau Keraly, C | 1 |
| Brachwitz, H; Ostermann, G; Till, U | 1 |
| Benveniste, J; Chignard, M; Le Couedic, JP; Vargaftig, BB | 2 |
| Chignard, M; Lefort, J; Vargaftig, BB; Wal, F | 1 |
| Rao, GH; White, JG | 1 |
| Gogstad, G; Solum, NO; Stormorken, H | 1 |
| Benveniste, J; Chignard, M; Vargaftig, BB | 1 |
| Morley, J; Page, CP; Paul, W | 1 |
| Benveniste, J; Fouque, F; Odiot, J; Vargaftig, BB | 1 |
| High, JA; Namm, DH | 1 |
| Cox, CP; Farr, RS; Jorgensen, R; Wardlow, ML | 1 |
| Brocchieri, A; Grignani, G; Moroni, M; Porta, C; Saporiti, A | 1 |
| Bond, SE; Dillingham, EO; Gollamudi, R; Herron, D; Lyman, BA; Salgia, SR; Zheng, X | 1 |
| Chern, JW; Chou, TC; Ding, YA; Yen, MH | 1 |
| Cho, PW; Gillinov, AM; Herskowitz, A; Kumar, P; Lee, PC; Poston, RS; Redmond, JM; Uthoff, K; Winkelstein, JA; Zehr, KJ | 1 |
| Evans, RJ; Hayes, LJ; Heath, MF; Littler, RM; McEvoy, RJ; Poole, AW | 1 |
| Burstein, SA; Dale, GL; George, JN; Heilmann, E; Hynes, LA | 1 |
| Berg, A; Le Blanc, K; Palmblad, J; Samuelsson, J | 1 |
| Hirata, Y; Nakano, M; Nakashima, M; Uematsu, T; Umemura, K | 1 |
| Bretschneider, E; Glusa, E; Schrör, K | 1 |
| Andries, R; Boichot-Lagente, E; Bourgain, RH; Decuyper, K; Paubert-Braquet, M; Shen, S | 1 |
| Connolly, TM; Endris, R; Karczewski, J | 1 |
| Farnaz, S; Malik, A; Saeed, SA; Simjee, RU | 1 |
| Cheung, HT; Fu, SL; Smal, MA | 1 |
| Kuo, YH; Lin, CH; Lin, YL; Teng, CM | 1 |
| Chen, IS; Hsiao, G; Ko, FN; Teng, CM; Wu, SJ | 1 |
| Hawes, AS; Isom, OW; Ko, W; Krieger, KH; Lang, D; Zelano, JA | 1 |
| Altman, R; Budd, SE; Chernoff, SB; Dollar, LE; Zucker, ML | 1 |
| Aishita, H; Fujitani, B; Katsube, N; Sakaguchi, K | 1 |
| Aarbakke, G; Holmsen, H; Steen, VM | 1 |
| Jørgensen, L; Kinlough-Rathbone, RL; Mustard, JF; Nilsen, GJ; Perry, DW | 1 |
| Cissik, JH; Dalton, LM; McGlasson, DL; Patterson, WR | 1 |
| Bonnar, J; Gleeson, N; Norris, LA; Sheppard, BL | 1 |
| Akkerman, JW; Bruijnzeel, PL; Burgers, JA; Koenderman, L; Schweizer, RC | 1 |
| Aye, MT; Ganz, PR; Hashemi, S; Palmer, DS | 1 |
| Hirata, Y; Matsuno, H; Nakashima, M; Takiguchi, Y; Uematsu, T; Umemura, K; Wada, K | 1 |
| Hanahan, DJ; Lekka, M; Tokumura, A; Tsuji, H | 1 |
| Akkerman, JW; Banga, JD; de Graaf, JC; Erkelens, DW; Sixma, JJ; van Breugel, HH; Westerveld, HT | 1 |
| Arnout, J; Deckmyn, H; Hoet, B; Kienast, J; Pfliegler, G; Vermylen, J; Wittevrongel, C | 1 |
| Belenkov, Yu; Chazova, I; Gabbasov, Z; Nakonechnicov, S; Popov, E | 1 |
| Heptinstall, S; Lösche, W; Sanderson, HM; Vickers, J | 1 |
| Ghosh, S; Rao, AK; Sun, L; Yang, X | 1 |
| Kanazawa, T; Onodera, K; Takanashi, S; Yasugahira, H | 1 |
| Elizarova, EP | 1 |
| Evans, RJ; Heath, MF; Jarvis, GE | 1 |
| Azizova, OA; Fortinskaia, ES; Khalilov, EM; Torkhovskaia, TI; Vlasova, II | 1 |
| Claude, JR; Godfroid, JJ; Heymans, F; Lamouri, A; Martin, C; Massicot, F; Pham-Huy, C; Warnet, JM | 1 |
| Cheryk, LA; Gentry, PA; Healey, R; Shanks, RD | 1 |
| Armani, U; Carrubba, M; Leoncini, G; Piana, A; Signorello, MG | 1 |
| Cheglakov, IB; Korotaeva, AA; Morozkin, AD; Prokazova, NV; Suslova, IV | 1 |
| Chang, YL; Hsueh, CM; Ko, FN; Lee, SS; Liu, KC; Teng, CM | 1 |
| Evanson, OA; Weiss, DJ | 1 |
| Edwards, CM; Heptinstall, S; Lowe, KC | 1 |
| Ablett, JM; Cunningham, FM; Fairbairn, SM; Lees, P; Page, CP | 1 |
| Saeed, SA; Shah, BH | 1 |
| Cole, AT; Hawkey, CJ; Heptinstall, S; May, JA | 1 |
| Gilani, AH; Majoo, RU; Saeed, SA; Shah, BH | 1 |
| Bonsignore, L; Calignano, A; Cottiglia, F; Loy, G | 1 |
| Chen, IS; Ishikawa, T; Teng, CM; Tsai, IL; Wun, MF | 1 |
| Evans, RJ; Hayes, LJ; Heath, MF | 1 |
| Ali, IQ; Gilani, AH; Nawaz, Z; Saeed, SA; Shah, BH; Virani, SS | 1 |
| Aida, Y; Fukaya, H; Kasama, T; Sugiyama, K; Takeuchi, N; Tobinaga, S | 1 |
| Ariga, T; Kobayashi, A; Kubota, K; Lim, H; Seki, T | 1 |
| Guo, ZG; Yi, FX | 1 |
| Baqai, FT; Hamid, F; Shehnaz, D; Uddin Ahmad, V | 1 |
| Chen, ZH; Duan, L; Shen, ZQ | 1 |
| Kinlough-Rathbone, RL; Packham, MA; Perry, DW; Rand, ML | 1 |
| Andrews, MJ; Bailey, SR; Cunningham, F; Elliott, J | 1 |
| Iwai, T; Machida, K; Maeda, T; Miwa, M; Sugatani, J; Tanaka, T; Watanabe, M | 1 |
| Andrews, MJ; Bailey, SR; Cunningham, FM; Elliott, J | 1 |
| Larson, DF; Parrish, PR | 1 |
| Afanasjeva, G; Avdonin, P; Baskova, I; Berezhnoy, S; Gabbasov, Z; Popov, E; Zavalova, L | 1 |
| Grignani, G; Maiolo, A; Porta, C; Tua, A | 1 |
| Gabbeta, J; Kaplan, R; Mao, GF; Rao, AK; Sun, L | 1 |
| Bath, P; Heptinstall, S; Zhao, L | 1 |
| Bonomini, M; Di Stante, S; Procopio, A; Robuffo, I; Sirolli, V; Strizzi, L | 1 |
| Akkerman, JW; den Dekker, E; Gorter, G; Heemskerk, JW; van der Vuurst, H | 1 |
| Bayly, WM; Kingston, JK; Meyers, KM; Sellon, DC; Wardrop, KJ | 1 |
| Chen, ZH; Hao, XJ; Li, L; Shen, YM; Shen, ZQ; Yang, XS; Zuo, GY | 1 |
| Dow, CS; Falcioni, G; Gabbianelli, R; Swoboda, B; Vince, FP | 1 |
| Cadaldini, M; D'Andrea, G; Granella, F | 1 |
| Chen, Z; Cheng, P; Dong, Z; Li, L; Liu, J; Shen, Z | 1 |
| Hu, H; Li, N; Zhang, W | 1 |
| Bosco, O; Camussi, G; Del Sorbo, L; Emanuelli, G; Fascio Pecetto, P; Goffi, A; Lupia, E; Montrucchio, G; Omedè, P | 1 |
| Chen, CL; Chou, JD; Chou, KJ; Chung, HM; Fang, HC; Hwang, YY; Jan, CR; Lee, PT | 1 |
| Chang, HT; Chen, JS; Cheng, HH; Ho, CM; Hsu, SS; Huang, CJ; Huang, JK; Jan, CR; Jiann, BP; Lo, YK; Yeh, JH | 1 |
| Chang, YL; Guo, NJ; Huang, P; Xiao, DJ | 1 |
| Antonopoulou, S; Demopoulos, CA; Fragopoulou, E; Karantonis, HC; Phenekos, C; Rementzis, J | 1 |
| Bingle, L; Brown, SB; Buttle, DJ; Dower, SK; Judge, HM; Sabroe, I; Storey, RF; Ward, JR; Whyte, MK | 1 |
| Bi, L; Bi, W; Cai, J; Fischer, NO; Liu, S; Peng, S; Tok, JB; Wang, G | 1 |
| Antonopoulou, S; Fragopoulou, E; Ginis, A; Karantonis, HC; Mitsou, E; Mourelatos, A; Phenekos, C; Rementzis, J; Sitara, M | 1 |
| Cattaneo, M; Lecchi, A; Lussana, F; Zighetti, ML | 1 |
| Holmes, CE; Madsen, NJ; Schneider, DJ; Serrano, FA; Sobel, BE | 1 |
| Fox, SC; Heptinstall, S; White, AE; Wilcox, RG; Xavier, RG | 1 |
| Gao, L; Lu, FR; Pan, LM; Qin, Y; Shen, L; Shi, W | 1 |
| Furuichi, M; Hisasue, M; Kitao, S; Kobayashi, K; Neo, S; Tatsuki, Y; Tsuchiya, R; Yamada, T | 1 |
| Keating, FK; Schneider, DJ | 1 |
| Chang, HW; Peng, S; Wang, W; Wang, Y; Zhang, X; Zhao, M; Zheng, M | 1 |
| Farhan, S; Glogar, D; Gyöngyösi, M; Hemetsberger, H; Hemetsberger, R; Huber, K; Pavo, I; Petrasi, Z; Posa, A; Sperker, W; Strehblow, C | 1 |
| Khadembashi, L; Kotthaus, J; Rehse, K | 1 |
| Schneider, DJ; Sobel, BE | 1 |
| Coy Barrera, ED; Cuca Suárez, LE | 1 |
| Shan, LC; Sun, YW; Wang, YQ; Xu, CL | 1 |
| Antman, EM; Braunwald, E; Costigan, TM; Frelinger, AL; Jakubowski, JA; McCabe, CH; Michelson, AD; Miller, DL; Neumann, FJ; Trenk, D; Wiviott, SD | 1 |
| Bai, L; Cen, J; Fang, W; Fu, J; Kong, Y; Li, Y; Xiong, J | 1 |
| Brass, LF; Chatterjee, MS; Colace, TV; Diamond, SL; Flamm, MH; Jaeger, D; Jing, H; Sinno, T; Zhou, S | 1 |
| Demopoulos, CA; Kolovou, G; Kolovou, V; Papakonstantinou, VD; Stamatakis, G; Verouti, SN; Xanthopoulou, MN | 1 |
| De Nucci, G; Donato, JL; Lilla, S; Lorenzetti, R; Maziero, AM | 1 |
| Barinov, EF; Mamedaliyeva, S; Tverdokhleb, TA | 1 |
| Feng, Q; Jiang, X; Liu, J; Ma, H; Peng, S; Tang, J; Wang, Y; Wu, J; Xu, W; Zhao, M; Zhu, H | 1 |
| Anderson, R; Durandt, C; Feldman, C; Mitchell, TJ; Nel, JG; Tintinger, GR | 1 |
| Huang, GJ; Kuo, PC; Lee, KH; Liao, YR; Tsai, WJ; Wu, TS | 1 |
| Antonopoulou, S; Laios, K; Moschos, MM; Moustafa, GA; Papakonstantinou, VD; Tsatsos, M | 1 |
| Androudi, S; Chatziralli, IP; Ladas, DS; Laios, K; Moschos, MM | 1 |
| Antonopoulou, S; Detopoulou, M; Fragopoulou, E; Gavriil, L; Petsini, F | 1 |
| Banerjee, A; Cohen, MJ; Coleman, JR; Kelher, MR; Moore, EE; Peltz, ED; Samuels, JM; Sauaia, A; Silliman, CC | 1 |
| Abhilasha, KV; Basrur, V; Campbell, RA; Cummings, RD; Jacob, SP; Lehoux, S; Manne, BK; Marathe, GK; McIntyre, TM; Rondina, MT; Sumanth, MS; Weyrich, AS; Yost, CC | 1 |
| Baldo, BA; Smal, MA | 1 |
| Fang, Q; Peng, S; Wang, Y; Wu, J; Yang, Y; Zhang, X; Zhao, M | 1 |
8 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and adenosine diphosphate
| Article | Year |
|---|---|
Role of paf-acether and related ether-lipid metabolism in platelets.
Topics: Acetyltransferases; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Cyclic AMP; Glycerylphosphorylcholine; Histamine Release; Humans; Hydrolysis; Phospholipases A; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin | 1985 |
[Antiplatelet agents: specific agonist inhibitors].
Topics: Adenosine Diphosphate; Animals; Neurotransmitter Agents; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1989 |
Role of thromboxane A2.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Humans; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thrombin; Thromboxane A2; Thromboxane B2 | 1985 |
Control and interrelation of aggregation and secretion; the roles of Ca2+, diacylglycerol and thromboxane with particular reference to ADP stimulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Calcium; Diglycerides; Epinephrine; Exocytosis; Glycerides; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, Purinergic; Thrombin; Thromboxane A2 | 1985 |
Receptors and receptor mechanisms of endogenous platelet stimulatory and inhibitory mediators.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Receptors, Cell Surface; Serotonin; Structure-Activity Relationship; Thrombin; Thromboxane A2; Vasopressins | 1986 |
An overview of antiplatelet and antithrombotic drugs.
Topics: Adenosine Diphosphate; Arachidonic Acids; Arteriosclerosis; Blood Platelets; Blood Vessels; Endothelium; Epoprostenol; Erythrocyte Aggregation; Fibrinolytic Agents; Hemostasis; Humans; Phospholipases A; Phospholipids; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandins; Receptors, Prostaglandin; Receptors, Thromboxane; Thrombin; Thromboembolism; Thromboxane-A Synthase; Type C Phospholipases | 1985 |
[Biochemical bases of platelet activity in homeostasis and thrombogenesis. III].
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Binding Sites; Collagen; Homeostasis; Humans; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; Thrombin; von Willebrand Factor | 1987 |
Present concepts on the mechanisms of platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Carrageenan; Crotalid Venoms; Humans; Lectins, C-Type; Lysophosphatidylcholines; Membrane Lipids; Phospholipases A; Platelet Activating Factor; Platelet Aggregation; Thromboxanes; Type C Phospholipases | 1981 |
9 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and adenosine diphosphate
| Article | Year |
|---|---|
Effect of temocillin and moxalactam on platelet responsiveness and bleeding time in normal volunteers.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Bleeding Time; Blood Platelets; Collagen; Humans; Male; Moxalactam; Penicillins; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic | 1985 |
Effect of diltiazem and low-dose aspirin on platelet aggregation and ATP release induced by paired agonists.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Aspirin; Bleeding Time; Blood Platelets; Diltiazem; Drug Synergism; Epinephrine; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1993 |
Effects of low-dose EPA-E on glycemic control, lipid profile, lipoprotein(a), platelet aggregation, viscosity, and platelet and vessel wall interaction in NIDDM.
Topics: Adenosine Diphosphate; Analysis of Variance; Blood Glucose; Blood Platelets; Blood Viscosity; Collagen; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Eicosapentaenoic Acid; Endothelium, Vascular; Erythrocyte Deformability; Extracellular Matrix; Female; Humans; In Vitro Techniques; Lipoprotein(a); Male; Middle Aged; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation | 1993 |
Platelet responses to several agonists and combinations of agonists in whole blood: a placebo controlled comparison of the effects of a once daily dose of plain aspirin 300 mg, plain aspirin 75 mg and enteric coated aspirin 300 mg, in man.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Coagulants; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Male; Placebos; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Ristocetin; Streptokinase; Tablets, Enteric-Coated | 1997 |
The inhibitory effect of cinchonine on human platelet aggregation due to blockade of calcium influx.
Topics: Adenosine Diphosphate; Antimalarials; Arachidonic Acid; Calcimycin; Calcium; Cinchona Alkaloids; Collagen; Epinephrine; Humans; Platelet Activating Factor; Platelet Aggregation Inhibitors; Reference Values; Signal Transduction | 1998 |
Effect of fast-food Mediterranean-type diet on type 2 diabetics and healthy human subjects' platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Body Weight; Diabetes Mellitus, Type 2; Diet; Diet, Mediterranean; Energy Intake; Food Analysis; Humans; Lipids; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Reference Values; Restaurants | 2006 |
Effect of traditional Greek Mediterranean meals on platelet aggregation in normal subjects and in patients with type 2 diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Diabetes Mellitus, Type 2; Diet, Mediterranean; Female; Greece; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Thrombin | 2006 |
Intrinsic platelet reactivity before P2Y12 blockade contributes to residual platelet reactivity despite high-level P2Y12 blockade by prasugrel or high-dose clopidogrel. Results from PRINCIPLE-TIMI 44.
Topics: Adenosine Diphosphate; Aged; Clopidogrel; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperazines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine | 2011 |
Consumption of plant extract supplement reduces platelet activating factor-induced platelet aggregation and increases platelet activating factor catabolism: a randomised, double-blind and placebo-controlled trial.
Topics: Adenosine Diphosphate; Adult; Biomarkers; Blood Platelets; Dietary Supplements; Double-Blind Method; Female; Healthy Volunteers; Humans; Leukocytes; Male; Plant Extracts; Platelet Activating Factor; Platelet Aggregation | 2019 |
282 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and adenosine diphosphate
| Article | Year |
|---|---|
Platelet adhesion and aggregation in diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Coagulation Factors; Blood Platelets; Diabetes Mellitus; Factor VIII; Humans; Imidazoles; Insulin; Male; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; von Willebrand Factor | 1979 |
Platelet-activating factor stimulates phosphoinositide turnover in neurohybrid NCB-20 cells: involvement of pertussis toxin-sensitive guanine nucleotide-binding proteins and inhibition by protein kinase C.
Topics: Adenosine Diphosphate; Animals; Brain; Calcium; Cricetinae; Cricetulus; GTP-Binding Proteins; Hybrid Cells; Membrane Proteins; Mice; Neuroblastoma; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Stimulation, Chemical; Virulence Factors, Bordetella | 1992 |
Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcium; Clot Retraction; Collagen; Cyclic AMP; Epinephrine; Fibrinogen; Hemorrhage; Humans; Indomethacin; Kinetics; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Reference Values; Thrombin; Vasoconstrictor Agents; von Willebrand Factor | 1992 |
Neutrophil elastase potentiates cathepsin G-induced platelet activation.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Cathepsin G; Cathepsins; Cyclic AMP; Drug Synergism; Humans; In Vitro Techniques; Molecular Sequence Data; Neutrophils; Oligopeptides; Pancreatic Elastase; Platelet Activating Factor; Platelet Activation; Serine Endopeptidases; Substrate Specificity | 1992 |
Platelets in patients with homozygous familial hypercholesterolemia are sensitive to Ca(2+)-mobilizing activity of low density lipoproteins.
Topics: Adenosine Diphosphate; Adolescent; Adult; Alprostadil; Blood Platelets; Calcium; Child; Cytoplasm; Epinephrine; Female; Homozygote; Humans; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Male; Platelet Activating Factor; Receptors, Cell Surface; Receptors, Lipoprotein | 1992 |
Effect of platelet agonists on the binding of platelet-activating factor to human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Fibrinogen; Humans; Iodine Radioisotopes; Platelet Activating Factor; Platelet Activation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thrombin | 1992 |
Calcium influx evoked by Ca2+ store depletion in human platelets is more susceptible to cytochrome P-450 inhibitors than receptor-mediated calcium entry.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cell Compartmentation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Econazole; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ion Channel Gating; Manganese; Miconazole; Osmolar Concentration; Platelet Activating Factor; Platelet Activation; Receptors, Cholinergic; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Terpenes; Thapsigargin; Thrombin; Vasopressins | 1992 |
The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit.
Topics: Adenosine Diphosphate; Animals; Arginine; Cerebrovascular Circulation; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Platelet Activation; Pulmonary Circulation; Rabbits | 1991 |
Pharmacological profile of G619, a new platelet aggregation inhibitor.
Topics: Adenosine Diphosphate; Animals; Benzamides; Calcium; Collagen; Dogs; Epinephrine; Fibrinogen; Humans; Male; Phenylacetates; Picolines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Shock, Septic; Sulfonamides; Thrombin; Thromboxane B2; Vasoconstriction | 1992 |
[Modulating effects of adenosine on the process of human platelet activation].
Topics: Adenosine; Adenosine Diphosphate; Humans; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin | 1992 |
Gamma-pyrone compounds. II: Synthesis and antiplatelet effects of tetraoxygenated xanthones.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Cells, Cultured; Collagen; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship; Xanthenes | 1992 |
Moderate exercise increases platelet function in type I diabetic patients without severe angiopathy and in good control.
Topics: Adenosine Diphosphate; Adult; beta-Thromboglobulin; Blood Glucose; Blood Platelets; Collagen; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Eating; Epinephrine; Exercise; Growth Hormone; Humans; Hydrocortisone; In Vitro Techniques; Insulin; Male; Norepinephrine; Platelet Activating Factor; Platelet Activation | 1992 |
In vitro and in vivo activities of the novel antiplatelet agent alpha,alpha'-bis[3-(N,N-diethylcarbamoyl)piperidino]-p-xylene dihydrobromide.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Fibrinolytic Agents; Humans; In Vitro Techniques; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Nipecotic Acids; Platelet Activating Factor; Platelet Aggregation Inhibitors | 1992 |
The human platelet as a reproducible and sensitive cell for the detection and assay of platelet-activating factor.
Topics: Adenosine; Adenosine Diphosphate; Adult; Biological Assay; Blood Platelets; Citric Acid; Female; Fibrinogen; Glucose; Humans; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Reproducibility of Results; Serotonin | 1992 |
Cell response kinetics: the phenomenon of supercooperativity in aggregation of human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Calcimycin; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Tetradecanoylphorbol Acetate; Thimerosal | 1992 |
Antiplatelet actions of some coumarin compounds isolated from plant sources.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Coumarins; Membrane Lipids; Molecular Structure; Phospholipids; Plants; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thrombin; Thromboxane B2 | 1992 |
Xanthines inhibit human platelet aggregation induced by platelet-activating factor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Theophylline; Xanthines | 1992 |
Inhibition by glaucocalyxin A of aggregation of rabbit platelets induced by ADP, arachidonic acid and platelet-activating factor, and inhibition of [3H]-PAF binding.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Diterpenes, Kaurane; Drugs, Chinese Herbal; Female; Glyceryl Ethers; In Vitro Techniques; Kinetics; Male; Molecular Structure; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiazoles | 1992 |
Humoral factor, intraplatelet calcium, and hypertension.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Blood Platelets; Calcium; Humans; Hypertension; Male; Middle Aged; Plasmapheresis; Platelet Activating Factor; Platelet Aggregation | 1992 |
Prehispanolone, a novel platelet activating factor receptor antagonist from Leonurus heterophyllus.
Topics: Adenosine Diphosphate; Animals; Cell Membrane; Diterpenes; Drugs, Chinese Herbal; Ginkgolides; In Vitro Techniques; Lactones; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Binding; Rabbits; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serum Albumin, Bovine; Sodium; Structure-Activity Relationship; Thrombin | 1991 |
Platelet-activating factor (PAF) receptor antagonists inhibit arachidonic acid induced platelet aggregation in rabbit whole blood.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Azepines; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Triazoles | 1991 |
[Aggregative behavior and calcium content of platelets in thrombocythemia and thrombocytosis].
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Collagen; Epinephrine; Humans; In Vitro Techniques; Myeloproliferative Disorders; Platelet Activating Factor; Platelet Aggregation; Reference Values; Thrombocytosis | 1990 |
Platelet response to the aggregatory effect of platelet activating factor (PAF) ex vivo in patients with acute myocardial infarction.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Drug Resistance; Epoprostenol; Humans; In Vitro Techniques; Male; Middle Aged; Myocardial Infarction; Platelet Activating Factor; Platelet Aggregation; Time Factors | 1991 |
Agonist-induced Ca2+ influx into human platelets is secondary to the emptying of intracellular Ca2+ stores.
Topics: Adenosine Diphosphate; Biological Transport; Blood Platelets; Calcium; Calcium Channel Agonists; Cell Membrane; Cytochrome P-450 Enzyme Inhibitors; Fura-2; Humans; Ionomycin; Manganese; Nickel; Platelet Activating Factor; Spectrometry, Fluorescence; Thrombin | 1991 |
Antibodies to platelet-activating factor (PAF) inhibit PAF-induced platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Antibodies; Calcimycin; Immunoglobulins; Platelet Activating Factor; Platelet Aggregation; Rabbits; Sheep; Species Specificity | 1991 |
Effects of platelet activating factor on rat platelets in vivo.
Topics: Adenosine Diphosphate; Animals; Azepines; Blood Platelets; In Vitro Techniques; Leukocytes; Male; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Count; Pulmonary Embolism; Rats; Rats, Inbred Strains; Triazoles | 1991 |
Inhibition by the PAF antagonist WEB 2086 of PAF induced inositol-1,4,5-trisphosphate production in human platelets.
Topics: Adenosine Diphosphate; Azepines; Blood Platelets; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Platelet Activating Factor; Thrombin; Triazoles | 1991 |
Protein kinase C and cyclic AMP regulate reversible exposure of binding sites for fibrinogen on the glycoprotein IIB-IIIA complex of human platelets.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Cyclic AMP; Epinephrine; Fibrinogen; Humans; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Signal Transduction; Temperature | 1991 |
Failure to detect platelet-activating factor using the splenectomized mouse bioassay.
Topics: Adenosine Diphosphate; Animals; Biological Assay; Blood Platelets; Cattle; Horses; Mice; Mice, Inbred Strains; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Splenectomy; Thrombin; Thrombocytopenia | 1991 |
In vitro platelet aggregability studies: lack of evidence for platelet hyperactivity in systemic sclerosis.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Coagulation Factors; Blood Platelets; Collagen; Female; Humans; In Vitro Techniques; Lactones; Middle Aged; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Scleroderma, Systemic | 1991 |
Effect of recombinant hirudin on cytosolic Ca2+ concentrations using different platelet stimulators.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Chromatography, Gel; Collagen; Cytosol; Dose-Response Relationship, Drug; Drug Interactions; Hirudins; Humans; Ionomycin; Platelet Activating Factor; Platelet Aggregation; Recombinant Proteins; Second Messenger Systems; Thrombin | 1991 |
Nitroprusside in vitro inhibits platelet aggregation and intracellular calcium translocation. Effect of haemoglobin.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Collagen; Hemoglobins; Humans; In Vitro Techniques; Intracellular Fluid; Nitroprusside; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
Some properties of rat platelet aggregation and effects of butylated hydroxytoluene, warfarin and aspirin.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Coagulation Factors; Butylated Hydroxytoluene; Collagen; Epinephrine; Male; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Inbred Strains; Ristocetin; Warfarin | 1991 |
Detection of platelet desensitization in pregnancy-induced hypertension is dependent on the agonist used.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Collagen; Female; Humans; Hypertension; Platelet Activating Factor; Platelet Aggregation; Pregnancy; Pregnancy Complications, Cardiovascular; Reference Values | 1991 |
Hemostatic studies in racing standardbred horses with exercise-induced pulmonary hemorrhage. Hemostatic parameters at rest and after moderate exercise.
Topics: Adenosine Diphosphate; Animals; Antithrombin III; Collagen; Factor VIII; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Hematocrit; Hemorrhage; Hemostasis; Horse Diseases; Horses; Lung Diseases; Partial Thromboplastin Time; Physical Exertion; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Prothrombin Time; Thrombin Time; von Willebrand Factor | 1991 |
Changes in parameters of the coagulation-fibrinolysis system and platelet function after OKY-046 administration to patients with ruptured aneurysm of the cerebral artery.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Blood Coagulation; Blood Platelets; Collagen; Female; Fibrinogen; Fibrinolysis; Humans; Intracranial Aneurysm; Male; Methacrylates; Middle Aged; Plasminogen Inactivators; Platelet Activating Factor; Rupture, Spontaneous; Thromboxane-A Synthase; Tissue Plasminogen Activator | 1991 |
Platelet aggregation in recombinant-hirudin-anticoagulated blood.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Citrates; Citric Acid; Collagen; Drug Synergism; Epinephrine; Hirudins; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Recombinant Proteins; Serotonin | 1991 |
Nutritional zinc increases platelet reactivity.
Topics: Adenosine Diphosphate; Blood Physiological Phenomena; Blood Platelets; Collagen; Epinephrine; Humans; Nutritional Physiological Phenomena; Platelet Activating Factor; Platelet Aggregation; Thrombin; Zinc | 1991 |
Changes of rabbit platelet function on simultaneous administration of ticlopidine hydrochloride and OKY-046.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arachidonic Acid; Collagen; Drug Interactions; Drug Synergism; Methacrylates; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Statistics as Topic; Ticlopidine | 1991 |
Effect of histamine receptor blockers on human platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Collagen; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation | 1990 |
Inhibition of PAF-induced human platelet responses by newly synthesized ether phospholipids.
Topics: Adenosine Diphosphate; Collagen; Humans; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Serotonin | 1991 |
Identification of 50 kDa snake venom proteins which specifically inhibit platelet adhesion to collagen.
Topics: Adenosine Diphosphate; Animals; Blotting, Western; Collagen; Epinephrine; Fatty Acids, Monounsaturated; Humans; In Vitro Techniques; Kinetics; Molecular Weight; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Snake Venoms; Snakes; Species Specificity | 1991 |
[The role of vitamin E during pregnancy--anti-platelet aggregation activity of alpha-tocopherol].
Topics: Adenosine Diphosphate; Chorionic Villi; Female; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pregnancy; Vitamin E | 1991 |
LDL- and agonist-induced Ca(2+)-mobilization in platelets of healthy subjects and in patients with familial hyperlipoproteinemia type II.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Coronary Disease; Cytosol; Epinephrine; Female; Humans; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Male; Platelet Activating Factor | 1991 |
Inhibitory effect of vitamin E (alpha-tocopherol) on spontaneous platelet aggregation in whole blood.
Topics: Adenosine Diphosphate; Adult; Aspirin; Creatine Kinase; Drug Synergism; Humans; In Vitro Techniques; Male; Phosphocreatine; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Verapamil; Vitamin E | 1990 |
Rapid and reversible inhibition by low density lipoprotein of the endothelium-dependent relaxation to hemostatic substances in porcine coronary arteries. Heat and acid labile factors in low density lipoprotein mediate the inhibition.
Topics: Acids; Adenosine Diphosphate; Animals; Calcimycin; Coronary Vasospasm; Coronary Vessels; Endothelium, Vascular; Female; Hot Temperature; In Vitro Techniques; Lipoproteins, LDL; Male; Muscle Relaxation; Nitric Oxide; Platelet Activating Factor; Swine; Thrombin; Thrombosis | 1990 |
Agonist-evoked changes in cytosolic pH and calcium concentration in human platelets: studies in physiological bicarbonate.
Topics: Adenosine Diphosphate; Bicarbonates; Blood Platelets; Butyrates; Calcium; Carbon Dioxide; Cytosol; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Meglumine; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Sodium; Spectrometry, Fluorescence; Thrombin | 1990 |
The correlation between Ca2+ influx and inositol 1, 4, 5-trisphosphate (IP3) formation in platelets stimulated by various agonists.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Humans; Inositol 1,4,5-Trisphosphate; Ionomycin; Platelet Activating Factor; Temperature; Thrombin; Thromboxane A2 | 1990 |
A comparative study of the effects of local anaesthetics on platelet aggregation.
Topics: Adenosine Diphosphate; Anesthetics, Local; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; In Vitro Techniques; Membrane Lipids; Platelet Activating Factor; Platelet Aggregation | 1990 |
Aequorin-detected calcium changes in stimulated thrombasthenic platelets. Aggregation-dependent calcium movement in response to ADP.
Topics: Adenosine Diphosphate; Aequorin; Blood Platelet Disorders; Blood Platelets; Calcimycin; Calcium; Collagen; Humans; In Vitro Techniques; Luminescent Proteins; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombasthenia; Thrombin | 1990 |
Radioisotopic model for investigating thromboembolism in the rabbit.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Erythrocytes; Female; Indium Radioisotopes; Male; Models, Biological; Organometallic Compounds; Oxyquinoline; Platelet Activating Factor; Rabbits; Radionuclide Imaging; Thrombin; Thromboembolism | 1990 |
Desensitization of the platelet aggregation response to adrenaline during insulin-induced hypoglycaemia in man.
Topics: Adenosine Diphosphate; Adult; Blood Glucose; Blood Platelets; Epinephrine; Humans; Hypoglycemia; Infusions, Intravenous; Injections, Intravenous; Insulin; Insulin, Regular, Pork; Kinetics; Male; Platelet Activating Factor; Platelet Aggregation; Recombinant Proteins | 1990 |
Inhibition of platelet function by polymorphonuclear leukocytes.
Topics: Adenosine Diphosphate; beta-Thromboglobulin; Blood Platelets; Calcium; Collagen; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Thrombin | 1990 |
Inhibition of rabbit platelet aggregation by 1,4-naphthoquinones.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Calcium; Collagen; Naphthoquinones; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thromboxane A2 | 1990 |
Evidence for the calcium-dependent activation of phospholipase D in thrombin-stimulated human erythroleukaemia cells.
Topics: Adenosine Diphosphate; Calcimycin; Calcium; Cell Line; Enzyme Activation; Epinephrine; Glycerophospholipids; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylinositols; Phospholipase D; Phospholipases; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1990 |
Leukocyte and platelet function and eicosanoid production in subjects with hypercholesterolaemia.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Fatty Acids; Female; Humans; Hyperlipoproteinemia Type II; Leukotriene B4; Lipids; Luminescent Measurements; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 1990 |
Platelet aggregation of migraineurs during and between attacks.
Topics: Adenosine Diphosphate; Adolescent; Adult; Blood Coagulation Factors; Collagen; Female; Humans; Male; Middle Aged; Migraine Disorders; Platelet Activating Factor; Platelet Aggregation; Time Factors | 1990 |
Endothelin-1 does not affect human platelet aggregation in whole blood and platelet rich plasma.
Topics: Adenosine Diphosphate; Adult; Collagen; Endothelins; Humans; In Vitro Techniques; Male; Plasma; Platelet Activating Factor; Platelet Aggregation | 1990 |
Platelet activating factor and sheep platelets: a sensitive new bioassay.
Topics: Adenosine Diphosphate; Alprazolam; Animals; Azepines; Biological Assay; Blood Platelets; Cell Separation; Furans; Platelet Activating Factor; Platelet Aggregation; Serotonin; Sheep; Thrombin; Triazines; Triazoles | 1990 |
Computerized optoelectronic induction and registration of arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Computers; Disease Models, Animal; Electric Stimulation; Endothelium, Vascular; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombosis | 1990 |
[Effect of cefaclor on guinea pig platelet aggregation in vitro].
Topics: Adenosine Diphosphate; Animals; Calcium; Cefaclor; Cephalexin; Fibrinogen; Guinea Pigs; In Vitro Techniques; Male; Membrane Glycoproteins; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1990 |
Agonists stimulate divalent cation channels in the plasma membrane of human platelets.
Topics: Adenosine Diphosphate; Aminoquinolines; Blood Platelets; Calcium; Cations, Divalent; Cell Membrane; Egtazic Acid; Fluorescent Dyes; Humans; Ion Channels; Kinetics; Manganese; Pentetic Acid; Platelet Activating Factor; Thrombin | 1985 |
Platelet membrane potential: simultaneous measurement of diSC3(5) fluorescence and optical density.
Topics: Adenosine Diphosphate; Amiloride; Benzothiazoles; Blood Platelets; Carbocyanines; Cell Membrane; Fluorescent Dyes; Gramicidin; Humans; Membrane Potentials; Platelet Activating Factor; Platelet Aggregation; Potassium Chloride; Quinolines; Tetrodotoxin; Thrombin; Valinomycin; Verapamil | 1985 |
AH6809, a prostaglandin DP-receptor blocking drug on human platelets.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Dinoprost; Epoprostenol; Humans; Hydantoins; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Receptors, Immunologic; Receptors, Prostaglandin; Xanthenes; Xanthones | 1988 |
How can we inhibit 5-HT-induced platelet aggregation and why should we bother?
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Amlodipine; Female; Humans; Male; Middle Aged; Nifedipine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Serotonin Antagonists; Verapamil | 1988 |
Blood platelet function in patients with obliterative arteriosclerosis of the lower limbs.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acids; Arteriosclerosis Obliterans; Biomarkers; Blood Platelets; Female; Humans; Leg; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation | 1988 |
Receptor-operated channels in human platelets.
Topics: Adenosine Diphosphate; Barium; Biological Transport; Blood Platelets; Cadmium; Calcium; Cesium; Electrophoresis, Gel, Two-Dimensional; Humans; Ion Channels; Lithium; Membrane Potentials; Nickel; Platelet Activating Factor; Sodium; Spectrometry, Fluorescence; Thrombin; Thromboxane A2 | 1989 |
Inhibitory effects of phenol derivatives on bovine platelet aggregation and their effects on Ca2+ mobilization.
Topics: 1-Octanol; Adenosine Diphosphate; Animals; Benzofurans; Blood Platelets; Calcimycin; Calcium; Cattle; Collagen; Cytoplasm; Fluorescent Dyes; Fura-2; Octanols; Phenols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Solubility; Spectrometry, Fluorescence; Thrombin; Water | 1989 |
[The thrombocyte-activation factor and endotoxin-induced thrombocyte activation].
Topics: Adenosine Diphosphate; Blood Platelets; Dose-Response Relationship, Drug; Endotoxins; Humans; In Vitro Techniques; Lipopolysaccharides; Neisseria meningitidis; Platelet Activating Factor; Platelet Aggregation; Salmonella typhimurium | 1989 |
The relationship of insulin antibodies, platelet-fixing immune complexes and platelet-associated IgG to in vitro platelet aggregation and thromboxane B2 synthesis in childhood type 1 (insulin-dependent) diabetes mellitus.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Child; Collagen; Diabetes Mellitus, Type 1; Epinephrine; Female; Humans; Immunoglobulin G; Immunoglobulins; In Vitro Techniques; Insulin Antibodies; Male; Platelet Activating Factor; Platelet Aggregation; Reference Values; Thromboxane B2 | 1989 |
[Kinetics of the cellular response: the phenomenon of supercooperativity in platelet aggregation].
Topics: Adenosine Diphosphate; Alprostadil; Arachidonic Acid; Arachidonic Acids; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1989 |
Reduced sensitivity of human platelets to PAF-acether following ticlopidine intake.
Topics: Adenosine Diphosphate; Administration, Oral; Arachidonic Acid; Arachidonic Acids; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 1989 |
Effect of the concentration of Ca2+ in the suspending medium on the responses of human and rabbit platelets to aggregating agents.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thromboxane B2 | 1989 |
The role of bradykinin on the effect of plasma kallikrein on platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Collagen; Humans; Kallikreins; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1989 |
Does acute experimental pancreatitis affect blood platelet function?
Topics: Acute Disease; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Dogs; Hemostasis; In Vitro Techniques; Pancreatitis; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Thromboxane B2 | 1989 |
Verapamil is a potent inhibitor of 5-HT-induced platelet aggregation.
Topics: Adenosine Diphosphate; Amlodipine; Calcium Channel Blockers; Collagen; Diltiazem; Epinephrine; Humans; In Vitro Techniques; Nifedipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin Antagonists; Verapamil | 1989 |
Epinephrine induces platelet fibrinogen receptor expression, fibrinogen binding, and aggregation in whole blood in the absence of other excitatory agonists.
Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Epinephrine; Fibrinogen; Flow Cytometry; Humans; Platelet Activating Factor; Platelet Aggregation; Receptors, Cell Surface; Receptors, Peptide; Serotonin; Thrombin | 1989 |
Monitoring of the activation of receptor-operated calcium channels in human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium Channels; Collagen; Humans; Platelet Activating Factor; Platelet Aggregation; Receptors, Cell Surface; Spectrometry, Fluorescence; Thrombin | 1989 |
Evidence for two mechanisms of thrombin-induced platelet activation: one proteolytic, one receptor mediated.
Topics: Adenosine Diphosphate; Humans; In Vitro Techniques; Leupeptins; Phosphatidylinositols; Platelet Activating Factor; Platelet Activation; Receptors, Cell Surface; Receptors, Thrombin; Serotonin; Thrombin; Thromboxane A2; Trypsin | 1989 |
Receptor-operated calcium channels in human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Calcium Channels; Collagen; Humans; Manganese; Platelet Activating Factor; Spectrometry, Fluorescence; Thrombin | 1989 |
Characterization of the normal bovine platelet aggregation response.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Cattle; Epinephrine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioimmunoassay; Serotonin; Thrombin; Thromboxane A2; Thromboxane B2 | 1989 |
Platelet aggregation in the Asian elephant is not dependent on thromboxane B2 production.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Elephants; Female; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Verapamil | 1989 |
Whole blood aggregation, thromboxane release and the lyso derivative of platelet activating factor in myocardial infarction and unstable angina.
Topics: Adenosine Diphosphate; Aged; Angina Pectoris; Angina, Unstable; Collagen; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1989 |
[New methodical approach to the study of platelet aggregation in vitro].
Topics: Adenosine Diphosphate; Humans; Kinetics; Methods; Models, Biological; Platelet Activating Factor; Platelet Aggregation; Platelet Count | 1989 |
Effect of metronidazole on platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Crotalid Venoms; Epinephrine; Guinea Pigs; Humans; Lectins, C-Type; Metronidazole; Platelet Activating Factor; Platelet Aggregation Inhibitors | 1989 |
In vivo method for the assessment of platelet accumulation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Drug Evaluation, Preclinical; Erythrocytes; Fibrinogen; Guinea Pigs; Indium Radioisotopes; Male; Microcomputers; Monitoring, Physiologic; Platelet Activating Factor; Platelet Aggregation; Radioisotope Dilution Technique | 1989 |
Platelet size affects both micro- and macro-aggregation: contributions of platelet number, volume fraction and cell surface.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Blood Platelets; Cell Membrane; Cell Separation; Humans; Kinetics; Microscopy, Phase-Contrast; Nephelometry and Turbidimetry; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Prostaglandin Endoperoxides, Synthetic; Ristocetin | 1989 |
[New approaches to the study of thrombocyte aggregation in patients with dilated cardiomyopathy].
Topics: Adenosine Diphosphate; Adolescent; Adult; Cardiomyopathy, Dilated; Culture Media; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Function Tests; Stimulation, Chemical | 1989 |
Suppression by tetrandrine of human platelet aggregation induced by platelet-activating factor and other stimulants.
Topics: Adenosine Diphosphate; Adult; Alkaloids; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Collagen; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin | 1989 |
Whole blood aggregation and plasma lyso-PAF related to smoking and atherosclerosis.
Topics: Adenosine Diphosphate; Adult; Aged; Arteriosclerosis; Cell Aggregation; Collagen; Humans; Male; Middle Aged; Platelet Activating Factor; Smoking; Thromboxane B2; Vascular Diseases | 1989 |
Insulin directly reduces platelet sensitivity to aggregating agents. Studies in vitro and in vivo.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Blood Platelets; Collagen; Cyclic AMP; Epinephrine; Humans; In Vitro Techniques; Insulin; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Thromboxane B2 | 1988 |
[Receptor-dependent regulation of the concentration of Ca2+ in the cytoplasm of thrombocytes in hypertensive patients].
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Cytoplasm; Humans; Hypertension; Male; Middle Aged; Platelet Activating Factor; Receptors, Cell Surface; Vasopressins | 1988 |
Reduced serum inhibition of platelet-activating factor activity in preeclampsia.
Topics: Adenosine Diphosphate; Adult; Chromatography, Thin Layer; Collagen; Female; Humans; Platelet Activating Factor; Platelet Aggregation; Pre-Eclampsia; Pregnancy; Ristocetin | 1989 |
Synergistic effects of platelet-activating factor and other platelet agonists in human platelet aggregation and release: the role of ADP and products of the cyclooxygenase pathway.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Calcimycin; Collagen; Drug Synergism; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Ristocetin; Thrombin | 1985 |
The influence of activating hormones on human platelet membrane Ca2+-ATPase activity.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Calcimycin; Calcium-Transporting ATPases; Cell Membrane; Colforsin; Ethers; Humans; Ionomycin; Kinetics; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1986 |
Antagonism of U46619-induced aggregation of human and canine platelets by four TXA2 receptor antagonists.
Topics: Adenosine Diphosphate; Animals; Dogs; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2 | 1986 |
Endogenous platelet-activating factor and anti-platelet-activating factor in patients with renovascular hypertension.
Topics: Adenosine Diphosphate; Adolescent; Adult; Angioplasty, Balloon; Arachidonic Acid; Arachidonic Acids; Female; Humans; Hypertension, Renovascular; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Renal Veins | 1988 |
[Calcium metabolism in arterial hypertension. I. Myocardial hypertrophy and hormone-dependent increase in Ca2+ levels in the thrombocytes of patients with arterial hypertension].
Topics: Adenosine Diphosphate; Adult; Aged; Blood Platelets; Calcium; Cardiomegaly; Humans; Hypercalcemia; Hypertension; In Vitro Techniques; Male; Middle Aged; Models, Cardiovascular; Platelet Activating Factor | 1988 |
Cyclic AMP inhibits platelet activation independently of its effect on cytosolic free calcium.
Topics: Adenosine Diphosphate; Aminoquinolines; Blood Platelets; Bucladesine; Calcimycin; Calcium; Cyclic AMP; Cytosol; Epoprostenol; Humans; Platelet Activating Factor; Thrombin | 1985 |
Mechanism of the inhibition of platelet aggregation produced by prostaglandin F2 alpha.
Topics: Adenosine Diphosphate; Aspirin; Cyclic AMP; Cyclic GMP; Dinoprost; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins F; Prostaglandins H; Prostaglandins, Synthetic; Thrombin | 1985 |
Beneficial effects of a new potent and specific thromboxane receptor antagonist (SQ-29,548) in vitro and in vivo.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydrazines; Lysosomes; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Prostaglandin-Endoperoxide Synthases; Rabbits; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase | 1985 |
Platelet-activating factor-mediated vasoconstriction and glycogenolysis in the perfused rat liver.
Topics: Adenosine Diphosphate; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Glucose; Hemodynamics; Liver Glycogen; Oxygen Consumption; Perfusion; Platelet Activating Factor; Portal Vein; Vasoconstriction; Venous Pressure; Verapamil | 1986 |
Agonist-induced inositol phospholipid metabolism and Ca++ flux in human platelet activation.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Epinephrine; Humans; Kinetics; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Serotonin; Thrombin; Vasopressins | 1985 |
Fibrinogen mitogenic effect on hemopoietic cell lines: control via receptor modulation.
Topics: Adenosine Diphosphate; Binding Sites; Binding, Competitive; Blood Platelets; Bucladesine; Cell Line; Edetic Acid; Fibrinogen; Hematopoietic Stem Cells; Humans; Mitogens; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Thrombin | 1986 |
A defect of platelet release reaction in a patient with SLE: impaired platelet aggregation induced by phorbol ester with a normal phosphorylation of 40K protein.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Proteins; Calcimycin; Collagen; Diglycerides; Epinephrine; Female; Humans; Lupus Erythematosus, Systemic; Phorbols; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombin | 1986 |
FR-900452, a specific antagonist of platelet activating factor (PAF) produced by Streptomyces phaeofaciens. I. Taxonomy, fermentation, isolation, and physico-chemical and biological characteristics.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Collagen; Fermentation; Indoles; Piperazines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Streptomyces | 1986 |
Synergistic platelet activation by aggregates of IgG and the phospholipid platelet-activating factor 1-O-alkyl-2-acetyl-SN-glycero-3-phosphorylcholine.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dose-Response Relationship, Drug; Drug Synergism; Humans; Immunoglobulin G; Kinetics; Macromolecular Substances; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1986 |
Augmentation of 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine (PAF)-induced human platelet activation by C-reactive protein.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; C-Reactive Protein; Circular Dichroism; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Freezing; Humans; Neutrophils; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Rabbits; Serotonin; Species Specificity | 1986 |
Specific inhibition of PAF-acether-induced platelet activation by BN 52021 and comparison with the PAF-acether inhibitors kadsurenone and CV 3988.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Benzofurans; Benzopyrans; Blood Platelets; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Lactones; Lignans; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Thiazoles | 1986 |
Platelet aggregation and thromboxane release induced by arachidonic acid, collagen, ADP and platelet-activating factor following low dose acetylsalicylic acid in man.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1986 |
Inhibitory effects of three new synthetic compounds on human platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Structure-Activity Relationship; Thiophenes; Thrombin | 1986 |
Platelet-activating factor (PAF-acether) induces high- and low-affinity binding of fibrinogen to human platelets via independent mechanisms.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Fibrinogen; Humans; Indomethacin; Kinetics; Macromolecular Substances; Platelet Activating Factor; Prostaglandin Endoperoxides; Protein Binding; Thromboxanes | 1986 |
Effect of phorbol 12-myristate 13-acetate (PMA) on agonist-induced arachidonate release and 5-hydroxytryptamine secretion in human platelets. Dependence of effects on agonist type and time of incubation with PMA.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Humans; In Vitro Techniques; Kinetics; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1987 |
Effects of the lipid peroxidation product 4-hydroxynonenal on the aggregation of human platelets.
Topics: Adenosine Diphosphate; Aldehydes; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Drug Antagonism; Fatty Acids; Glutathione; Humans; In Vitro Techniques; Malondialdehyde; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1987 |
Antiplatelet effect of butylidenephthalide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Coagulation Factors; Calcimycin; Collagen; Dinoprostone; Guinea Pigs; Humans; In Vitro Techniques; Phthalic Acids; Phthalic Anhydrides; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Thrombin; Thromboxane B2 | 1987 |
Porcine coronary arteries with regenerated endothelium have a reduced endothelium-dependent responsiveness to aggregating platelets and serotonin.
Topics: Adenosine Diphosphate; Animals; Calcimycin; Coronary Circulation; Coronary Vessels; Endothelium; In Vitro Techniques; Male; Microscopy, Electron; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Platelet Activating Factor; Platelet Aggregation; Regeneration; Serotonin; Swine; Thrombin; Vasopressins | 1987 |
Antagonists of PAF-acether do not suppress thrombin-induced aggregation of ADP-deprived and aspirin-treated human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspirin; Blood Platelets; Crotalid Venoms; Cyclooxygenase Inhibitors; Diterpenes; Ginkgolides; Glyceryl Ethers; Humans; Lactones; Lectins, C-Type; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Pyridines; Thiazoles; Thrombin | 1987 |
Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Diglycerides; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Platelet Activating Factor; Platelet Aggregation; Protein Kinase C; Sphingosine; Thrombin | 1987 |
Platelet-activating factor in the inflammatory exudate in the anaphylactic phase of allergic inflammation in rats.
Topics: Adenosine Diphosphate; Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Exudates and Transudates; Inflammation; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Inbred Strains; Thiazoles | 1987 |
The kinetics of changes in intracellular calcium concentration in fura-2-loaded human platelets.
Topics: Adenosine Diphosphate; Benzofurans; Blood Platelets; Calcium; Colforsin; Dose-Response Relationship, Drug; Egtazic Acid; Fluorometry; Fura-2; Humans; Kinetics; Nickel; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Thrombin; Vasopressins | 1987 |
Effects of ethanol on pathways of platelet aggregation in vitro.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Ethanol; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thrombin | 1988 |
Human platelet electrorotation change induced by activation: inducer specificity and correlation to serotonin release.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Cell Membrane; Collagen; Cytoplasmic Granules; Electric Conductivity; Electrophysiology; Epinephrine; Humans; Kinetics; Microscopy, Electron; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin | 1988 |
Effect of rat phosphorylcholine-binding protein on platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Carrier Proteins; Dose-Response Relationship, Drug; Isoelectric Point; Phosphorylcholine; Platelet Activating Factor; Platelet Aggregation; Rats | 1988 |
Biological effects of the orally active platelet activating factor receptor antagonist SDZ 64-412.
Topics: Adenosine Diphosphate; Animals; Blood Pressure; Bronchi; Cebus; Collagen; Dogs; Dose-Response Relationship, Drug; Epinephrine; Guinea Pigs; Isoquinolines; Mice; Platelet Activating Factor; Platelet Aggregation; Rats | 1988 |
[Calcium metabolism of the thrombocytes in ischemic heart disease].
Topics: Adenosine Diphosphate; Adult; Aged; Angina Pectoris; Blood Platelets; Calcium; Coronary Disease; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Activating Factor; Platelet Aggregation; Time Factors | 1988 |
Plasma components are required for platelet activation by the toxin of Loxosceles reclusa.
Topics: Adenosine Diphosphate; Arthropod Venoms; Blood Platelets; Calcium; Fibrinogen; Humans; In Vitro Techniques; Plasma; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Serotonin; Spider Venoms | 1988 |
Release of acetylhydrolase from platelets on aggregation with platelet-activating factor.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Hydrogen-Ion Concentration; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin | 1988 |
Abnormal platelet response to PAF and ADP in beta-thalassaemia.
Topics: Adenosine Diphosphate; Genetic Carrier Screening; Homozygote; Humans; In Vitro Techniques; Kinetics; Platelet Activating Factor; Platelet Aggregation; Reference Values; Splenectomy; Thalassemia | 1988 |
Activity of platelet-activating factor (PAF) acetylhydrolase in plasma from patients with ischemic cerebrovascular disease.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adenosine Diphosphate; Aged; Aged, 80 and over; Apoproteins; Cerebrovascular Disorders; Enzyme Induction; Female; Humans; Lipids; Male; Middle Aged; Phospholipases; Phospholipases A; Platelet Activating Factor; Platelet Aggregation | 1988 |
Effect of a Paf antagonist, WEB 2086, on airway microvascular leakage in the guinea-pig and platelet aggregation in man.
Topics: Adenosine Diphosphate; Animals; Azepines; Capillary Permeability; Guinea Pigs; Humans; In Vitro Techniques; Male; Ovalbumin; Platelet Activating Factor; Platelet Aggregation; Triazines; Triazoles | 1988 |
Whole blood platelet aggregation is not affected by cigarette smoking but is sex-related.
Topics: Adenosine Diphosphate; Adolescent; Adult; Blood Coagulation; Collagen; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Sex Factors; Smoking; Thromboxane B2 | 1987 |
Interaction of a new low molecular weight heparin (OP/LMWH) with human platelets.
Topics: Adenosine Diphosphate; Blood Coagulation Factors; Blood Platelets; Epoprostenol; Heparin; Humans; Kinetics; Molecular Weight; Platelet Activating Factor; Platelet Aggregation | 1986 |
Prolonged bleeding time, reduced platelet aggregation, altered PAF-acether sensitivity and increased platelet mass are a trait of asthma and hay fever.
Topics: Adenosine Diphosphate; Adult; Asthma; Bleeding Time; Collagen; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Platelet Function Tests; Rhinitis, Allergic, Seasonal; Thromboxane B2 | 1986 |
Phorbol esters sensitize platelets to activation by physiological agonists.
Topics: Adenosine Diphosphate; Alprostadil; Collagen; Humans; Kinetics; Phorbol Esters; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Structure-Activity Relationship; Vasopressins | 1987 |
Effect of platelet agonists on airway reactivity and intrathoracic platelet accumulation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Female; Guinea Pigs; In Vitro Techniques; Indium Radioisotopes; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Respiratory System | 1987 |
Contribution of ADP to the amplification of primary platelet aggregation by platelet activating factor (PAF): modulatory role of aspirin.
Topics: Adenosine Diphosphate; Aspirin; Creatine Kinase; Drug Interactions; Humans; Kinetics; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation | 1986 |
Comparison of the effects of low molecular weight heparin and unfractionated heparin on activation of human platelets in vitro.
Topics: Adenosine Diphosphate; Calcium; Dose-Response Relationship, Drug; Heparin; Humans; Male; Molecular Weight; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1986 |
Effect of indomethacin and dazoxiben on intravascular platelet aggregation in the anaesthetized rabbit.
Topics: Adenosine Diphosphate; Animals; Collagen; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Male; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Thromboxane B2 | 1986 |
Inhibition of platelet aggregation by amiloride.
Topics: Adenosine Diphosphate; Amiloride; Blood Platelets; Collagen; Depression, Chemical; Humans; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1986 |
[Free cytoplasmic calcium and thrombocyte aggregation in patients with ischemic heart disease. The effect of ADP, thrombocyte activation factor and serotonin].
Topics: Adenosine Diphosphate; Adult; Angina Pectoris; Blood Platelets; Calcium; Coronary Artery Disease; Coronary Disease; Cytoplasm; Humans; Male; Middle Aged; Myocardial Infarction; Physical Exertion; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1986 |
Polymeric inhibitors of platelet aggregation. II. Copolymers of dipyridamole and related drugs with N-vinylpyrrolidone.
Topics: Adenosine Diphosphate; Dipyridamole; Humans; Kinetics; Mass Spectrometry; Mopidamol; Platelet Activating Factor; Platelet Aggregation; Polymers; Povidone; Structure-Activity Relationship | 1987 |
In vivo arterial platelet-vessel wall interaction and thrombosis: induction, on-line registration and ultrastructural control.
Topics: Adenosine Diphosphate; Animals; Arteries; Blood Platelets; Glycoproteins; Guinea Pigs; Male; Microscopy, Electron, Scanning; Platelet Activating Factor; Polysaccharides; Quinacrine; Rats; Rats, Inbred Strains; Thrombosis | 1985 |
Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Chromonar; Collagen; Coronary Disease; Coumarins; Disease Models, Animal; Dogs; Epinephrine; Male; Platelet Activating Factor; Platelet Aggregation; Regional Blood Flow; Thromboxane B2 | 1985 |
Platelets, endothelium, and vasospasm.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Dinoprost; Endothelium; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandins F; Serotonin; Thromboxanes; Vasoconstriction | 1985 |
Ultrastructural evidence for extravascular platelet recruitment in the lung upon intravenous injection of platelet-activating factor (PAF-acether) to guinea-pigs.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Bronchi; Constriction, Pathologic; Epoprostenol; Female; Guinea Pigs; Lung; Microscopy, Electron; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Time Factors | 1985 |
Possible participation of adenosine 5'-diphosphate, arachidonic acid and paf-acether in the platelet pro-aggregating effect of uncontrolled insulin-dependent diabetic erythrocytes in vitro.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Diabetes Mellitus, Type 1; Erythrocytes; Glutaral; Humans; Plasma; Platelet Activating Factor; Platelet Aggregation | 1985 |
Action mechanism of the platelet aggregation inducer and inhibitor from Echis carinatus snake venom.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chymotrypsin; Collagen; Fibrinogen; Heparin; Hirudins; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Thrombin; Viper Venoms | 1985 |
Subcellular localization of vasopressin-like material in platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Blood Platelets; Calcimycin; Collagen; Epinephrine; Humans; Microscopy, Electron; Norepinephrine; Platelet Activating Factor; Subcellular Fractions | 1985 |
The effect of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (paf-acether) on the arterial wall.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arteries; Diterpenes; Edetic Acid; Epoprostenol; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Quinacrine; Thrombosis | 1985 |
Identification of platelet inhibitor present in the melon (Cucurbitacea cucumis melo).
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Collagen; Epinephrine; Fruit; Humans; Kinetics; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thrombin | 1985 |
Biological activity of platelet activating factor-amidophosphonate (PAF-AP), a novel phosphonolipid selective inhibitor of platelet activating factor (PAF).
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Diglycerides; Epinephrine; Humans; Oxidation-Reduction; Phosphatidic Acids; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1985 |
Methionine-enkephalin does not alter human platelet aggregatory response.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Collagen; Enkephalin, Methionine; Epinephrine; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1985 |
Desensitization of human platelets by platelet activating factor.
Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Temperature; Thrombin | 1985 |
Regulation of human platelet activation--analysis of cyclooxygenase and cyclic AMP-dependent pathways.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Serotonin; Thrombin; Thromboxane B2 | 1984 |
Release of a slow-reacting substance from rabbit platelets.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Autacoids; Blood Platelets; Chromatography, High Pressure Liquid; Cysteine; Indomethacin; Kinetics; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin | 1981 |
Platelet-activating factor-induced aggregation of human platelets specifically inhibited by triazolobenzodiazepines.
Topics: Adenosine Diphosphate; Alprazolam; Anti-Anxiety Agents; Arachidonic Acid; Arachidonic Acids; Benzodiazepines; Blood Platelets; Calcimycin; Chromatography, Gel; Collagen; Epinephrine; Humans; Platelet Activating Factor; Platelet Aggregation; Thrombin; Triazolam | 1984 |
Inhibition of platelet adenylate cyclase by 1-O-alkyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine (platelet-activating factor).
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Creatine Kinase; Cyclic AMP; Indomethacin; Lysophosphatidylcholines; Phosphocreatine; Platelet Activating Factor; Prostaglandins E; Rabbits | 1982 |
Synergized activation of human platelets by epinephrine and platelet-activating factor-acether is adenosine diphosphate and thromboxane A2-independent.
Topics: Adenosine Diphosphate; Drug Synergism; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1983 |
Effect of prostacyclin on platelet-activating factor induced rabbit and platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Aorta; Blood Platelets; Bucladesine; Epoprostenol; Isoproterenol; Kinetics; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Prostaglandins, Synthetic; Rabbits; Serotonin; Theophylline | 1980 |
Human platelet activation by an alkylacetyl analogue of phosphatidylcholine.
Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Coagulation Factors; Blood Platelets; Calcium; Cyclooxygenase Inhibitors; Epinephrine; Epoprostenol; Humans; Ion Channels; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1982 |
Platelet products and vascular PGI2 production.
Topics: Adenosine Diphosphate; Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Platelets; Blood Vessels; Epoprostenol; Humans; Lysophospholipids; Male; Phosphatidic Acids; Platelet Activating Factor; Prostaglandins; Rabbits; Rats; Serotonin; Species Specificity; Umbilical Arteries | 1983 |
CV-3988 - a specific antagonist of platelet activating factor (PAF).
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Calcimycin; Collagen; Dose-Response Relationship, Drug; Male; Micelles; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains; Thiazoles | 1983 |
Stimulation of calcium uptake by 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) in rabbit platelets: possible involvement of the lipoxygenase pathway.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport, Active; Blood Platelets; Calcium; Indomethacin; Platelet Activating Factor; Rabbits; Verapamil | 1983 |
Studies on the stimulation of human blood platelets by semi-synthetic platelet-activating factor.
Topics: Adenosine Diphosphate; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Serotonin; Time Factors | 1983 |
Effects of tris on responses of human and rabbit platelets to aggregating agents.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Thrombin; Tromethamine | 1984 |
Effects of acetyl glyceryl ether phosphorylcholine on human platelet function in vitro.
Topics: Adenosine Diphosphate; Apyrase; beta-Thromboglobulin; Blood Platelets; Calcium; Creatine Kinase; Drug Synergism; Humans; Lysophosphatidylcholines; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Platelet Factor 4; Serotonin; Thromboxane A2 | 1981 |
Compound 48/80 is a potent inhibitor of human platelet aggregation antagonizing the calmodulin-dependent platelet reaction in vitro.
Topics: Adenosine Diphosphate; Calmodulin; Collagen; Humans; In Vitro Techniques; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1984 |
Lack of evidence for human lymphokines with thrombocyte aggregating activity. An in vitro study.
Topics: Adenosine Diphosphate; Blood Coagulation Factors; Epinephrine; Humans; In Vitro Techniques; Lymphocytes; Lymphokines; Phytohemagglutinins; Platelet Activating Factor; Platelet Aggregation; Tuberculin | 1984 |
Total and selective desensitisation of human platelets to synthetic platelet activating factor (PAF): evidence that extracellular PAF does not mediate collagen-induced aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aspirin; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Extracellular Space; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic | 1983 |
Diadenosine triphosphate (Ap3A) mediates human platelet aggregation by liberation of ADP.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Alkaline Phosphatase; Dinucleoside Phosphates; Humans; Platelet Activating Factor; Platelet Aggregation | 1984 |
Inhibition by ticlopidine of Paf-acether-induced in vitro aggregation of rabbit and human platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Humans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thiophenes; Ticlopidine | 1984 |
Halo lipids. VI. Stimulation of human and rabbit blood platelets by racemic halo analogues of O-alkyl-glycerophosphocholine.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chromatography, Gel; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Stimulation, Chemical | 1984 |
Platelet-activating factor (PAF-acether) secretion from platelets: effect of aggregating agents.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Coagulation Factors; Blood Platelets; Calcimycin; Collagen; In Vitro Techniques; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Time Factors | 1980 |
One, two, three or more pathways for platelet aggregation.
Topics: Acetophenones; Adenosine Diphosphate; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thrombin; Thromboxane A2 | 1980 |
Inhibition by sulphinpyrazone of the platelet-dependent bronchoconstriction due to platelet-activating factor (PAF-acether) in the guinea pig.
Topics: Adenosine Diphosphate; Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bronchi; Guinea Pigs; In Vitro Techniques; Lysophosphatidylcholines; Muscle Contraction; Platelet Activating Factor; Platelet Count; Sulfinpyrazone | 1982 |
Platelet activating factor (PAF) causes human platelet aggregation through the mechanism of membrane modulation.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cell Membrane; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Time Factors | 1982 |
A new bleeding disorder: lack of platelet aggregatory response to adrenaline and lack of secondary aggregation to ADP and platelet activating factor (PAF).
Topics: Adenosine Diphosphate; Adolescent; Blood Coagulation Tests; Blood Platelet Disorders; Epinephrine; Hemorrhagic Disorders; Humans; Male; Platelet Activating Factor; Platelet Aggregation | 1983 |
An in vivo model for studying platelet aggregation and disaggregation.
Topics: Abdomen; Acetylcholine; Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Guinea Pigs; Indium; Lysophosphatidylcholines; Male; Models, Biological; Platelet Activating Factor; Platelet Aggregation; Radioisotopes; Rats; Rats, Inbred Lew; Thorax | 1982 |
Adrenaline and PAF-acether synergize to trigger cyclooxygenase-independent activation of plasma-free human platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Creatine Kinase; Drug Synergism; Epinephrine; Humans; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Rabbits; Stimulation, Chemical; Thromboxane B2 | 1982 |
Thrombin-induced formation of a polar lipid material within platelets that possesses platelet-activating activity.
Topics: Adenosine Diphosphate; Animals; Apyrase; Arachidonic Acids; Blood Platelets; Cattle; Indomethacin; Lipids; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin | 1980 |
The presence of platelet-activating factor (PAF) in normal human mixed saliva.
Topics: Adenosine Diphosphate; Adult; Animals; Arachidonic Acids; Creatine Kinase; Dose-Response Relationship, Immunologic; Female; Hirudins; Humans; Indomethacin; Lysophosphatidylcholines; Male; Middle Aged; Platelet Activating Factor; Rabbits; Saliva; Serotonin; Thrombin | 1981 |
Effect of different platelet agonists on intracellular free Ca++ concentrations in human tumor cells: possible role in tumor growth.
Topics: Adenosine Diphosphate; Adult; Blood Coagulation; Blood Platelets; Calcium; Cell Communication; Cell Division; Collagen; HeLa Cells; Humans; Intracellular Fluid; Leukotriene B4; Melanoma; Mesothelioma; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet-Derived Growth Factor; Thrombin; Thromboxane B2; Tumor Cells, Cultured; Verapamil | 1995 |
Inhibition of PAF-induced human platelet aggregation by antithrombotic nipecotomides.
Topics: Adenosine Diphosphate; Adult; Binding, Competitive; Blood Platelets; Chromatography, Gel; Collagen; Female; Humans; Male; Nipecotic Acids; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Stereoisomerism | 1995 |
Antiplatelet actions of 2-(4-[1-(2-chlorophenyl) piperazinyl]) methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one compound.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Cyclic AMP; Epinephrine; Fibrinogen; Humans; Imidazoles; Pancreatic Elastase; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Quinazolines; Rabbits; Receptors, Cell Surface; Signal Transduction; Thromboxane A2; Thromboxane B2 | 1995 |
Platelet activating factor inhibition reduces lung injury after cardiopulmonary bypass.
Topics: Adenosine Diphosphate; Animals; Blood Cell Count; Cardiopulmonary Bypass; CD18 Antigens; Lung; Lung Compliance; Platelet Activating Factor; Platelet Aggregation; Pulmonary Circulation; Quinolinium Compounds; Respiratory Distress Syndrome; Swine; Vascular Resistance | 1995 |
The effects of aspirin and paracetamol on the aggregation of equine blood platelets.
Topics: Acetaminophen; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Size; Collagen; Dose-Response Relationship, Drug; Horses; In Vitro Techniques; Nephelometry and Turbidimetry; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2 | 1994 |
Fluorescein derivatization of fibrinogen for flow cytometric analysis of fibrinogen binding to platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cellular Senescence; Dogs; Edetic Acid; Fibrinogen; Flow Cytometry; Fluoresceins; Humans; Platelet Activating Factor; Platelet Activation | 1994 |
Stimulus-specific defect in platelet aggregation in polycythemia vera.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Blood Platelets; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Luminescent Measurements; Middle Aged; Multiple Myeloma; Platelet Activating Factor; Platelet Aggregation; Polycythemia Vera; Tetradecanoylphorbol Acetate | 1994 |
Enhancement of thrombotic arterial occlusion following cholesterol feeding in the guinea-pig: a role for thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arterial Occlusive Diseases; Cholesterol, Dietary; Collagen; Femoral Artery; Guinea Pigs; Male; Photochemistry; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thrombosis; Thromboxane A2; Time Factors | 1994 |
ADP-, PAF- and adrenaline-induced platelet aggregation and thromboxane formation are not affected by a thromboxane receptor antagonist at physiological external Ca++ concentrations.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Calcium; Citric Acid; Collagen; Epinephrine; Glucose; Hirudins; Humans; Indomethacin; Phenylacetates; Platelet Activating Factor; Platelet Aggregation; Receptors, Thromboxane; Recombinant Proteins; Sulfonamides; Thromboxanes | 1994 |
An optoelectronic registration method as applied to PAF-mediated hydrogen peroxide induced arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Animals, Laboratory; Arterial Occlusive Diseases; Arterioles; Electroshock; Endothelium, Vascular; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Male; Mesenteric Arteries; Platelet Activating Factor; Rats; Rats, Wistar; Thrombosis | 1994 |
Disagregin is a fibrinogen receptor antagonist lacking the Arg-Gly-Asp sequence from the tick, Ornithodoros moubata.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Blood Platelets; Cell Adhesion; Chromatography, Gel; Chromatography, High Pressure Liquid; Collagen; Endothelium, Vascular; Epinephrine; Humans; Kinetics; Molecular Sequence Data; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Salivary Glands; Salivary Proteins and Peptides; Thrombin; Ticks; Umbilical Cord | 1994 |
Triterpenes and B-sitosterol from piper betle: isolation, antiplatelet and anti-inflammatory effects.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Areca; Aspirin; Chromatography, Liquid; Edema; Humans; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Sitosterols; Triterpenes | 1993 |
Inhibition of platelet aggregation by diterpene acids from Pinus massoniana resin.
Topics: Adenosine Diphosphate; Animals; Calcimycin; Diterpenes; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Conformation; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1994 |
Inhibition of platelet thromboxane formation and phosphoinositides breakdown by diisoeugenol.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Collagen; Cyclic AMP; Eugenol; Humans; Membrane Lipids; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thromboxanes | 1994 |
Inhibition of collagen-induced platelet aggregation and adhesion by a pseudocyanide derivative of avicine isolated from Zanthoxylum integrifoliolum Merr.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cell Adhesion; Collagen; Dioxoles; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Inositol Phosphates; Phenanthridines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin D2; Proteoglycans; Rabbits; Structure-Activity Relationship; Thromboxane B2 | 1993 |
Platelet-activating factor antagonism attenuates platelet and neutrophil activation and reduces myocardial injury during coronary reperfusion.
Topics: Adenosine Diphosphate; Animals; Female; Furans; Heart; Hemodynamics; Hydrogen Peroxide; Hydrogen-Ion Concentration; Male; Myocardial Reperfusion Injury; Neutrophils; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Burst; Sheep; Ventricular Function, Left | 1993 |
Anti-platelet and anti-thrombotic effects of OP-41483.alpha-CD, a prostacyclin analogue, in experimental animals.
Topics: Adenosine Diphosphate; alpha-Cyclodextrins; Animals; Arachidonic Acid; Blood Coagulation Factors; Blood Platelets; Blood Pressure; Collagen; Cyclodextrins; Dogs; Epoprostenol; Female; Fibrinolytic Agents; Humans; Macaca; Male; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Rabbits; Rats; Rats, Wistar; Species Specificity; Thrombocytopenia | 1993 |
The platelet-stimulating effect of adrenaline through alpha 2-adrenergic receptors requires simultaneous activation by a true stimulatory platelet agonist. Evidence that adrenaline per se does not induce human platelet activation in vitro.
Topics: Adenosine Diphosphate; Epinephrine; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Prostaglandins; Receptors, Adrenergic, alpha-2; Thrombin; Time Factors | 1993 |
Rabbit lung macrophages stimulate platelets in vitro as observed by density-gradient centrifugation and transmission electron microscopy.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Cell Communication; Cells, Cultured; Centrifugation, Density Gradient; Creatine Kinase; Edetic Acid; Ferric Compounds; Macrophages, Alveolar; Microscopy, Electron; Phosphocreatine; Platelet Activating Factor; Platelet Activation; Rabbits; Thrombin; Triazolam | 1993 |
Aggregation of killer whale platelets.
Topics: Adaptation, Physiological; Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcimycin; Collagen; Dolphins; Epinephrine; Female; Male; Platelet Activating Factor; Platelet Aggregation; Ristocetin; Thromboxane B2; Time Factors | 1993 |
Whole blood platelet aggregation in moderate and severe pre-eclampsia.
Topics: Adenosine Diphosphate; Arachidonic Acid; Collagen; Epinephrine; Female; Humans; Platelet Activating Factor; Platelet Aggregation; Postpartum Period; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third | 1993 |
Regulation of the receptor for platelet-activating factor on human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkaloids; Antimycin A; Blood Platelets; Calmodulin; Cyclic AMP; Deoxyglucose; Energy Metabolism; Humans; Phosphoproteins; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sphingosine; Staurosporine; Sulfonamides | 1993 |
Human platelets secrete chemotactic activity for eosinophils.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Azepines; Blood Platelets; Calcium; Chemotactic Factors; Chemotaxis, Leukocyte; Cytoplasmic Granules; Cytosol; Eosinophils; Humans; Platelet Activating Factor; Platelet Factor 4; Platelet Storage Pool Deficiency; Prostaglandin Endoperoxides; Thromboxane A2; Triazoles | 1993 |
Platelet-activating factor secreted by DDAVP-treated monocytes mediates von Willebrand factor release from endothelial cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cells, Cultured; Cytokines; Deamino Arginine Vasopressin; Dioxolanes; Endothelium, Vascular; Epoprostenol; Humans; Kinetics; Monocytes; Platelet Activating Factor; Prostaglandins; von Willebrand Factor | 1993 |
Roles of platelet-activating factor, thromboxane A2, ADP and thrombin in thrombogenesis in the guinea pig.
Topics: Adenosine Diphosphate; Animals; Azepines; Biphenyl Compounds; Guinea Pigs; Heptanoic Acids; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thromboxane A2; Ticlopidine; Triazoles | 1993 |
Isolation of a phospholipid inhibitor of platelet activating factor-induced activity from perfused rat liver: identification as phosphatidylglycerol.
Topics: Adenosine Diphosphate; Animals; Chromatography, Thin Layer; Liver; Male; Perfusion; Phosphatidylglycerols; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Rabbits; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Fast Atom Bombardment; Thrombin | 1993 |
Sodium fluoride induced activation of phospholipase C in intact human platelets does not depend on ADP, PAF or arachidonate products.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Enzyme Activation; GTP-Binding Proteins; Humans; Lysine; Phospholipid Ethers; Platelet Activating Factor; Sodium Fluoride; Type C Phospholipases | 1993 |
Platelet aggregation in patients with primary pulmonary hypertension.
Topics: Adenosine Diphosphate; Blood Platelets; Humans; Hypertension, Pulmonary; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prognosis | 1996 |
Studies on the effects of agonists and antagonists on platelet shape change and platelet aggregation in whole blood.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Azepines; Blood Platelets; Humans; In Vitro Techniques; Piperazines; Piperidines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Serotonin; Succinates; Sulfonamides; Thromboxane A2; Triazoles; Vasoconstrictor Agents | 1996 |
Human platelet signaling defect characterized by impaired production of inositol-1,4,5-triphosphate and phosphatidic acid and diminished Pleckstrin phosphorylation: evidence for defective phospholipase C activation.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Diglycerides; Enzyme Activation; Female; Hemorrhagic Disorders; Humans; Inositol 1,4,5-Trisphosphate; Male; Middle Aged; Myosin Light Chains; Phosphatidic Acids; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoproteins; Phosphoric Diester Hydrolases; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Protein Processing, Post-Translational; Serotonin; Signal Transduction; Thrombin | 1996 |
[The changes of blood gas analysis values and platelet aggregability on acute phase in the experimental model of pulmonary embolism prepared by sephadex G-75 (SG-75) injection].
Topics: Acute-Phase Reaction; Adenosine Diphosphate; Animals; Blood Gas Analysis; Carbon Dioxide; Dextrans; Disease Models, Animal; Male; Oxygen; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Pulmonary Embolism; Rabbits | 1996 |
Effects of taurine on calcium in platelets and their aggregation.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Coronary Disease; Cytosol; Female; Humans; Hypertension; In Vitro Techniques; Kinetics; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Taurine | 1996 |
The role of ADP in endotoxin-induced equine platelet activation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Blood Platelets; Endotoxins; Female; Horses; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Spectrophotometry | 1996 |
[Effect of a micellar preparation of polyunsaturated phosphatidylcholine on platelet aggregation in vitro].
Topics: Adenosine Diphosphate; Fatty Acids, Unsaturated; Humans; Micelles; Myocardial Ischemia; Phosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1996 |
Preventive effects of two PAF-antagonists, PMS 536 and PMS 549, on cyclosporin-induced LLC-PK1 oxidative injury.
Topics: Acetylglucosaminidase; Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cyclosporine; Glutathione; Glutathione Peroxidase; Kidney Diseases; LLC-PK1 Cells; Oxidative Stress; Piperazines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Swine | 1997 |
An inherited platelet function defect in a Simmental crossbred herd.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Coagulation Disorders; Blood Platelets; Cattle; Cattle Diseases; Factor XI; Female; Hemorrhage; Heterozygote; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Function Tests | 1997 |
Hyperactivity and increased hydrogen peroxide formation in platelets of NIDDM patients.
Topics: Adenosine Diphosphate; Aged; beta-Thromboglobulin; Blood Platelets; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniques; Male; Middle Aged; Platelet Activating Factor; Risk Factors; Thrombin; Thrombosis | 1997 |
Effect of lysophosphatidylcholine on the structure and function of low density lipoproteins.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Hemofiltration; Humans; Lipoproteins, LDL; Lysophosphatidylcholines; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship; Thrombin | 1997 |
Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aporphines; Arachidonic Acid; Blood Platelets; Collagen; Cyclic AMP; Guaiacol; Humans; Isoquinolines; Isotope Labeling; Lipoxygenase Inhibitors; Male; Phenanthrenes; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinolines; Rabbits; Radioimmunoassay; Structure-Activity Relationship; Thrombin; Thromboxane B2; Vasoconstrictor Agents | 1997 |
Detection of activated platelets and platelet-leukocyte aggregates in horses.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Blood Platelets; Cell Aggregation; Erythrocytes; Fibrinogen; Flow Cytometry; Horses; Humans; Leukocytes; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin | 1997 |
Effects of the co-polymer surfactant, Pluronic F-68, on platelet aggregation in human whole blood.
Topics: Adenosine Diphosphate; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Poloxalene; Polymers; Reference Values; Surface-Active Agents | 1997 |
Influence of antigen challenge on platelet responsiveness in horses with chronic obstructive pulmonary disease.
Topics: Adenosine Diphosphate; Allergens; Animals; Antigens; Blood Platelets; Horse Diseases; Horses; Lung Diseases, Obstructive; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Poaceae; Time Factors | 1997 |
Diversity of agonist-mediated signal transduction pathways in human platelets.
Topics: Adenosine Diphosphate; Androstadienes; Arachidonic Acid; Blood Platelets; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Epinephrine; Humans; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Platelet Aggregation; Serotonin; Signal Transduction; Wortmannin | 1997 |
Anti-thrombotic and anti-inflammatory activities of protopine.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Benzophenanthridines; Berberine Alkaloids; Blood Platelets; Carrageenan; Edema; Fibrinolytic Agents; Histamine H1 Antagonists; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rabbits; Rats; Rats, Sprague-Dawley; Thromboxane A2 | 1997 |
One-step synthesis and pharmacological activity of new (N-substituted)amino-spiroalkan-dione derivatives.
Topics: Adenosine Diphosphate; Animals; Collagen; Cyclobutanes; Molecular Structure; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reference Standards; Spectrum Analysis; Spiro Compounds | 1997 |
Anti-platelet aggregation constituents from Formosan Toddalia asiatica.
Topics: Adenosine Diphosphate; Alkaloids; Arachidonic Acid; Benzoquinones; Blood Platelets; Collagen; Coumarins; Humans; Molecular Structure; Plant Extracts; Plant Stems; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Taiwan; Thrombin | 1998 |
Dextran-70 inhibits equine platelet aggregation induced by PAF but not by other agonists.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Anticoagulants; Collagen; Dextrans; Dose-Response Relationship, Drug; Horses; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Serotonin | 1998 |
Effects of chroman derivatives on platelet aggregation induced by some aggregating agents in rabbits.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Chromans; Collagen; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship | 1998 |
Inhibitory effect of sulfur-containing compounds in Scorodocarpus borneensis Becc. on the aggregation of rabbit platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Coagulation Factors; Collagen; Hemostatics; Hexanes; Inhibitory Concentration 50; Octanes; Plant Extracts; Plants, Edible; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Sulfur Compounds; Thrombin; Trees; Vasoconstrictor Agents | 1999 |
Platelet-released ADP stabilizes PAF-induced rabbit platelet aggregation by stabilizing intracellular calcium.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Calcium; Platelet Activating Factor; Platelet Aggregation; Rabbits | 1998 |
Effect of the crude extract of Cestrum parqui on carrageenin-induced rat paw oedema and aggregation of human blood platelets.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Edema; Male; Pakistan; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Solanaceae | 1999 |
Effect of protopine on cytosolic Ca2+ in rabbit platelets.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Arachidonic Acid; Benzophenanthridines; Berberine Alkaloids; Biological Transport, Active; Blood Platelets; Calcium; Female; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits | 1999 |
Effects of cathepsin G pretreatment of platelets on their subsequent responses to aggregating agents.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Anti-Bacterial Agents; Blood Platelets; Cathepsin G; Cathepsins; Drug Interactions; Hemostatics; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Ristocetin; Serine Endopeptidases; Serotonin; Thrombin; Vasoconstrictor Agents | 1999 |
Actions and interactions of ADP, 5- HT, histamine and PAF on equine platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Drug Interactions; Histamine; Horses; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 2000 |
Inhibition of rabbit platelet aggregation by nucleoside 5'-alkylphosphates: correlation with inhibition of agonist-induced calcium influx.
Topics: Adenosine Diphosphate; Animals; Calcium; Drug Interactions; Ion Transport; Ionomycin; Nucleotides; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Uridine Monophosphate | 2000 |
Differential activation of platelets from normal and allergic ponies by PAF and ADP.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate; Animals; Dermatitis, Contact; Eicosanoids; Horse Diseases; Horses; Hypersensitivity, Immediate; Platelet Activating Factor; Platelet Activation; Seasons; Serotonin; Signal Transduction; Thromboxane B2 | 2000 |
Pharmacological effect of nitroprusside on platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Dose-Response Relationship, Drug; Epinephrine; Humans; Middle Aged; Nitric Oxide Donors; Nitroprusside; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1999 |
Inhibition of induced and spontaneous platelet aggregation by destabilase from medicinal leech.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Cardiovascular Diseases; Collagen; Dose-Response Relationship, Drug; Endopeptidases; Fibrinolytic Agents; Humans; Leeches; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 2000 |
Amifostine, a reactive oxigen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF.
Topics: Adenosine Diphosphate; Adult; Amifostine; Antioxidants; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Nitric Oxide; Oxidative Stress; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Radiation-Protective Agents; Reactive Oxygen Species; Thromboxane B2 | 2000 |
Combined defect in membrane expression and activation of platelet GPIIb--IIIa complex without primary sequence abnormalities in myeloproliferative disease.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aged; Antibodies, Monoclonal; Binding Sites; Blood Platelets; Calcimycin; Diglycerides; DNA, Complementary; Enzyme Activators; Flow Cytometry; Humans; Immunoblotting; Intercellular Signaling Peptides and Proteins; Ionophores; Macrophage-1 Antigen; Male; Myeloproliferative Disorders; Neutrophils; Peptides; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymerase Chain Reaction; Protein Binding; Protein Kinase C; Receptors, Thrombin; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Signal Transduction | 2000 |
Effects of combining three different antiplatelet agents on platelets and leukocytes in whole blood in vitro.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Aspirin; Blood Platelets; Cell Communication; Dipyridamole; Drug Synergism; Flow Cytometry; Humans; Leukocytes; Macrophage-1 Antigen; Monocytes; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 2001 |
Platelet activation and platelet-erythrocyte aggregates in end-stage renal disease patients on hemodialysis.
Topics: Adenosine Diphosphate; Aged; Blood Platelets; Cell Aggregation; Complement C3a; Erythrocytes; Female; Heparin; Humans; Kidney Failure, Chronic; Male; Membranes, Artificial; Microscopy, Electron; Middle Aged; Platelet Activating Factor; Platelet Activation; Renal Dialysis | 2001 |
Biogenesis of G-protein mediated calcium signaling in human megakaryocytes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Calcium Signaling; Cattle; Cell Differentiation; Cells, Cultured; Fetal Blood; Flow Cytometry; Gene Expression Regulation, Developmental; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Iloprost; Megakaryocytes; Platelet Activating Factor; Protein Isoforms; Proto-Oncogene Proteins; Stem Cells; Thrombin; Thrombopoietin | 2001 |
Effects of formaldehyde fixation on equine platelets using flow cytometric methods to evaluate markers of platelet activation.
Topics: Adenosine Diphosphate; Animals; Annexin A5; Blood Platelets; Calcimycin; Fixatives; Flow Cytometry; Formaldehyde; Horses; Ionophores; Platelet Activating Factor; Platelet Activation | 2002 |
Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Diterpenes; Female; Fibrinolytic Agents; Ginkgolides; In Vitro Techniques; Indicators and Reagents; Lactones; Male; Plant Extracts; Plant Roots; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Spiraea | 2002 |
A new method to evaluate spontaneous platelet aggregation in type 2 diabetes by Cellfacts.
Topics: Adenosine Diphosphate; Antioxidants; Azepines; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Triazoles; Vitamin E | 2003 |
Platelet aggregation profiles in cluster headache.
Topics: Adenosine Diphosphate; Adolescent; Adult; Cluster Headache; Collagen; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation | 2003 |
Effects of plumbagin on platelet aggregation and platelet-neutrophil interactions.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; In Vitro Techniques; Male; Naphthoquinones; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits | 2003 |
Glycoprotein IIb/IIIa inhibition attenuates platelet-activating factor-induced platelet activation by reducing protein kinase C activity.
Topics: Adenosine Diphosphate; Adolescent; Adult; Antibodies, Monoclonal; Blood Platelets; CD11b Antigen; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Immunoblotting; Leukocytes; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; P-Selectin; Peptide Fragments; Peptides; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Thromboxane A2, Prostaglandin H2; Time Factors | 2003 |
Mechanisms of the priming effect of low doses of lipopoly-saccharides on leukocyte-dependent platelet aggregation in whole blood.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood; Blood Platelets; Cell Adhesion; Drug Interactions; Epinephrine; Humans; Leukocytes; Lipopolysaccharide Receptors; Lipopolysaccharides; Membrane Glycoproteins; Platelet Activating Factor; Platelet Aggregation; Receptors, Cell Surface; Toll-Like Receptor 4; Toll-Like Receptors | 2003 |
Platelet hyperreactivity in hemodialysis patients with frequently occluded vascular access.
Topics: Adenosine Diphosphate; Arachidonic Acid; Calcium; Catheters, Indwelling; Diabetes Mellitus; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Activation; Renal Dialysis; Thrombin; Thrombosis | 2004 |
Defect in regulation of Ca2+ movement in platelets from patients with systemic lupus erythematosus.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Calcium; Calcium Signaling; Female; Fluorescent Dyes; Fura-2; Humans; Lupus Erythematosus, Systemic; Patients; Platelet Activating Factor; Thrombin | 2005 |
[Activation of platelet-neutrophil mediated by platelet-activating factor].
Topics: Adenosine Diphosphate; Adult; Blood Platelets; CD11b Antigen; Cell Adhesion; Cell Communication; Female; Flow Cytometry; Ginkgolides; Humans; Male; Middle Aged; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled | 2005 |
Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor.
Topics: Adenosine Diphosphate; Antibodies; Atherosclerosis; Blood Platelets; Calcium; Cell Line; Epinephrine; Humans; Lipopolysaccharides; Lipoproteins; Megakaryocytes; P-Selectin; Platelet Activating Factor; Platelet Activation; Platelet Membrane Glycoprotein IIb; Toll-Like Receptor 2; Toll-Like Receptor 4; Vasoconstrictor Agents | 2005 |
Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates.
Topics: Adenosine Diphosphate; Animals; Carbolines; Drug Design; Fibrinolytic Agents; Free Radical Scavengers; Hydrogen; Molecular Structure; Oligopeptides; PC12 Cells; Phenol; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Thrombosis | 2006 |
Platelet aggregation studies: autologous platelet-poor plasma inhibits platelet aggregation when added to platelet-rich plasma to normalize platelet count.
Topics: Adenosine Diphosphate; Apyrase; Artifacts; Buffers; Centrifugation; Collagen; Humans; Nephelometry and Turbidimetry; Plasma; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Platelet Function Tests; Platelet-Rich Plasma | 2007 |
Influence of preparative procedures on assay of platelet function and apparent effects of antiplatelet agents.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Benzothiazoles; Blood Platelets; Coronary Disease; Crotalid Venoms; Flow Cytometry; Fluorescent Dyes; Hemostatics; Humans; Lectins, C-Type; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Quinolines; Thrombin; Tirofiban; Tyrosine | 2007 |
Enhanced platelet aggregation and activation under conditions of hypothermia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Monophosphate; Anticoagulants; Antigens, CD; Aspirin; Blood Platelets; Blood Specimen Collection; Citrates; Cold Temperature; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hirudins; Humans; Hypothermia, Induced; In Vitro Techniques; P-Selectin; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Platelet Membrane Glycoproteins; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Receptors, Thrombin; Tetraspanin 30; Time Factors | 2007 |
[Study on composing mechanism by effect of disassembled compositions of Yiqi Huoxue decoction on platelet aggregation of health adults].
Topics: Adenosine Diphosphate; Adult; Angelica sinensis; Arachidonic Acid; Astragalus propinquus; Drug Combinations; Drug Synergism; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Young Adult | 2007 |
Characterization of canine platelet activation induced by platelet activating factor (PAF).
Topics: Adenosine Diphosphate; Animals; Calcium; Collagen; Dogs; Platelet Activating Factor; Platelet Activation; Sulfonamides | 2008 |
The influence of platelet activating factor on the effects of platelet agonists and antiplatelet agents in vitro.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Blood Platelets; Crotalid Venoms; Drug Synergism; Female; Humans; Lectins, C-Type; Male; Middle Aged; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Thrombin | 2009 |
(3S)-N-(L-Aminoacyl)-1,2,3,4-tetrahydroisoquinolines, a class of novel antithrombotic agents: synthesis, bioassay, 3D QSAR, and ADME analysis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Biological Assay; Dose-Response Relationship, Drug; Fibrinolytic Agents; Molecular Structure; Platelet Activating Factor; Platelet Aggregation; Quantitative Structure-Activity Relationship; Rats; Tetrahydroisoquinolines; Thrombin | 2008 |
Association between the efficacy of dual antiplatelet therapy and the development of in-stent neointimal hyperplasia in porcine coronary arteries.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Animals; Aspirin; Cell Proliferation; Clopidogrel; Collagen; Coronary Angiography; Coronary Stenosis; Coronary Vessels; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Fibrin; Hyperplasia; Inflammation Mediators; Metals; P-Selectin; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prosthesis Design; Stents; Swine; Ticlopidine; Time Factors; Tunica Intima | 2008 |
New 1H-pyrazole-4-carboxamides with antiplatelet activity.
Topics: Adenosine Diphosphate; Amides; Cells, Cultured; Epinephrine; Humans; Inhibitory Concentration 50; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazoles; Structure-Activity Relationship | 2009 |
Streamlining the design of promising clinical trials: in-vitro testing of antithrombotic regimens and multiple agonists of platelet activation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Clinical Trials as Topic; Coronary Artery Disease; Crotalid Venoms; Drug Evaluation, Preclinical; Drug Therapy, Combination; Eptifibatide; Fibrinolytic Agents; Flow Cytometry; Heparin; Hirudins; Humans; Lectins, C-Type; P-Selectin; Peptide Fragments; Peptides; Pilot Projects; Platelet Activating Factor; Platelet Activation; Platelet Function Tests; Recombinant Proteins; Research Design; Thrombin | 2009 |
In vitro inhibitory activities of Lauraceae aporphine alkaloids.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aporphines; Arachidonic Acid; Circular Dichroism; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; In Vitro Techniques; Lauraceae; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Leaves; Platelet Activating Factor; Platelet Aggregation; Rabbits | 2010 |
[Inhibitory effect of TBN on platelet aggregation in rabbit].
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Drugs, Chinese Herbal; Male; Nephelometry and Turbidimetry; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazines; Rabbits | 2010 |
New peptide pENW (pGlu-Asn-Trp) inhibits platelet activation by attenuating Akt phosphorylation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Fibrinolytic Agents; Male; Oligopeptides; P-Selectin; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Pyrrolidonecarboxylic Acid; Rabbits; Rats; Rats, Sprague-Dawley; Thrombosis | 2012 |
Multiscale prediction of patient-specific platelet function under flow.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Calcium; Crotalid Venoms; HEK293 Cells; Humans; Lectins, C-Type; Male; Microfluidic Analytical Techniques; Models, Biological; Platelet Activating Factor; Platelet Function Tests; Predictive Value of Tests; Receptors, Thromboxane; Reference Values; Signal Transduction; Thrombosis; Vasoconstrictor Agents | 2012 |
Platelet activating factor levels and metabolism in Tangier disease: a case study.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Adenosine Diphosphate; Adult; Aged; Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Assay; Blood Platelets; Coronary Artery Disease; Diacylglycerol Cholinephosphotransferase; Female; Humans; Middle Aged; Mutation; Platelet Activating Factor; Platelet Aggregation; Rabbits; Reference Values; Tangier Disease; Thrombin | 2012 |
Inhibition of human platelet aggregation by eosinophils.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Chromatography, Gel; Collagen; Cytosol; Dextrans; Eosinophils; HL-60 Cells; Humans; Indomethacin; Male; Molecular Weight; NG-Nitroarginine Methyl Ester; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Wistar; Thrombin; Time Factors | 2013 |
[Interaction of the Humoral Agonist During the Platelets Activation in Patients with Chronic Cerebral Ischemia].
Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Platelets; Brain; Brain Ischemia; Chronic Disease; Epinephrine; Female; Humans; Intracranial Thrombosis; Male; Microcirculation; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Serotonin | 2015 |
Aqueous extract of Rabdosia rubescens leaves: forming nanoparticles, targeting P-selectin, and inhibiting thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Coagulation; Blood Platelets; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Flow Cytometry; Hydroxybenzoates; Isodon; Magnetic Resonance Spectroscopy; Male; Nanoparticles; P-Selectin; Plant Extracts; Plant Leaves; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Rosmarinic Acid; Spectrometry, Mass, Electrospray Ionization; Thrombin; Thrombosis | 2015 |
Pneumolysin Mediates Platelet Activation In Vitro.
Topics: Adenosine Diphosphate; Bacterial Proteins; Blood Platelets; Calcium; Calcium Chelating Agents; Cytosol; Egtazic Acid; Humans; In Vitro Techniques; P-Selectin; Platelet Activating Factor; Platelet Activation; Streptolysins; Up-Regulation | 2016 |
Bioactive chemical constituents from the root bark of Morus australis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Dose-Response Relationship, Drug; Flavonoids; Mice; Molecular Structure; Morus; Nitric Oxide; Plant Roots; Platelet Activating Factor; Platelet Aggregation; Rabbits; RAW 264.7 Cells; Structure-Activity Relationship | 2017 |
Anti-platelet effects of anti-glaucomatous eye drops: an in vitro study on human platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Glaucoma; Humans; Mediator Complex; Ophthalmic Solutions; Platelet Activating Factor; Platelet Aggregation | 2017 |
Anti-platelet effects of vitamin supplements in age-related macular degeneration: an in vitro study.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Dietary Supplements; Healthy Volunteers; Humans; Inhibitory Concentration 50; Macular Degeneration; Platelet Activating Factor; Platelet Aggregation; Receptors, Thrombin; Vitamins | 2018 |
Female platelets have distinct functional activity compared with male platelets: Implications in transfusion practice and treatment of trauma-induced coagulopathy.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Coagulation; Blood Coagulation Disorders; Blood Platelets; Estradiol; Female; Healthy Volunteers; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Postmenopause; Premenopause; Receptors, Fibrinogen; Sex Factors; Wounds and Injuries; Young Adult | 2019 |
Different glycoforms of alpha-1-acid glycoprotein contribute to its functional alterations in platelets and neutrophils.
Topics: Adenosine Diphosphate; Biomarkers; Blood Platelets; Cyclic AMP; Extracellular Traps; Glycosylation; Humans; Models, Biological; Neutrophil Activation; Neutrophils; Orosomucoid; Peptides; Platelet Activating Factor; Platelet Aggregation; Polysaccharides; Protein Isoforms | 2021 |
Inhibition of platelet-activating factor (PAF)-induced platelet aggregation by fatty acids from human saliva.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcimycin; Fatty Acids; Humans; Ionophores; Mammals; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Saliva; Thrombin | 2022 |
(1R,3S)-THCCA-Asn: To show the discovery of selective inhibitor of thrombin by successfully combining virtual screening and biological assay.
Topics: Adenosine Diphosphate; Amino Acids; Animals; Arachidonic Acids; Biological Assay; Blood Platelets; Carboxylic Acids; Cattle; Mammals; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Thrombin; Thrombosis | 2022 |