1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with aa 861 in 19 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (aa 861) | Trials (aa 861) | Recent Studies (post-2010) (aa 861) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 290 | 2 | 34 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | aa 861 (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 1.7 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 1.045 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Mus musculus (house mouse) | 0.032 | |
| 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | Cavia porcellus (domestic guinea pig) | 1.7 | |
| M17 leucyl aminopeptidase | Plasmodium falciparum 3D7 | 53.45 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 15 (78.95) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haston, WO; Morrissey, MM; Quintavalla, JC; Rediske, JJ; Seligman, B | 1 |
| Ito, Y; Tashiro, K; Xie, Z | 1 |
| Bergström, M; Carlsson, J; Gáti, I; Långström, B; Muhr, C | 1 |
| Adachi, M; Idaira, K; Imai, T; Maeda, M; Saito, C; Takahashi, T; Tsuji, A | 1 |
| Kurachi, Y; Nakajima, T; Sugimoto, T | 1 |
| Hara, A; Ikeda, M; Kaneko, H; Shiba, T; Takeuchi, S; Yoshida, H | 1 |
| Hirasawa, N; Mue, S; Ohuchi, K; Omata, M; Sugidachi, A; Tsurufuji, S; Watanabe, M | 1 |
| Kobayashi, K; Mizoguchi, Y; Morisawa, S; Sakagami, Y; Seki, S; Yamamoto, S | 1 |
| Niwa, Y; Ohashi, T; Ozaki, Y | 1 |
| Hirai, A; Saito, H; Tamura, Y; Yoshida, S | 1 |
| Iwama, T; Nagai, H; Sakurai, T; Yamaguchi, S | 1 |
| Kimura, J; Namura, Y; Shio, H | 1 |
| Arakida, Y; Hirasawa, N; Mue, S; Ohuchi, K; Sugidachi, A; Tanabe, J; Watanabe, M | 1 |
| Chang, SW; Chen, CR; Voelkel, NF | 1 |
| Huang, YC; Kennedy, TP; Piantadosi, CA; Su, YF; Watkins, WD; Whorton, AR | 1 |
| Matsuzaki, T; Noguchi, K; Ojiri, Y; Sakanashi, M; Shiroma, N | 1 |
| Kawauchi, Y; Masuho, Y; Takasaki, J | 1 |
| Brasch, F; Falk, S; Göggel, R; Heydasch, U; Müller, KM; Uhlig, S; Wendel, A | 1 |
| Ibe, BO; Raj, JU | 1 |
19 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and aa 861
| Article | Year |
|---|---|
Platelet activating factor stimulates intracellular calcium transients in human neutrophils: involvement of endogenous 5-lipoxygenase products.
Topics: Arachidonate 5-Lipoxygenase; Benzoquinones; Calcium; Humans; Intracellular Fluid; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1992 |
Effects of PAF on excitatory neuro-effector transmission in dog airways.
Topics: Acetylcholine; Animals; Benzoquinones; Bronchi; Carbachol; Dogs; Electric Stimulation; Female; In Vitro Techniques; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Pyrilamine; Synaptic Transmission; Trachea | 1992 |
Application of (methyl-11C)-methionine in the multicellular spheroid system.
Topics: Benzeneacetamides; Benzoquinones; Carbon Radioisotopes; Cell Aggregation; Cell Line; Cycloheximide; Humans; Hydroxamic Acids; In Vitro Techniques; Lipoxygenase Inhibitors; Methionine; Platelet Activating Factor; Pyridinium Compounds; Tumor Cells, Cultured | 1991 |
[The role of 5-lipoxygenase products in the development of airway responsiveness induced by platelet activating factor inhalation in dogs].
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzoquinones; Bronchoalveolar Lavage Fluid; Dogs; Eosinophils; Female; Leukocyte Count; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Respiratory Hypersensitivity | 1991 |
Platelet-activating factor activates cardiac GK via arachidonic acid metabolites.
Topics: Animals; Arachidonic Acids; Benzoquinones; Cells, Cultured; Flavanones; Flavonoids; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; Heart Atria; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Membrane Potentials; Myocardium; Platelet Activating Factor; Potassium Channels; Virulence Factors, Bordetella | 1991 |
Mechanism of acute gastrointestinal mucosal damage in endotoxic shock and the effect of Fragmin.
Topics: Acute Disease; Animals; Benzoquinones; Dogs; Gastric Mucosa; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Intestinal Mucosa; Leukotriene B4; Lipoxygenase Inhibitors; Necrosis; Phospholipid Ethers; Platelet Activating Factor; Shock, Septic | 1990 |
Possible role for platelet-activating factor in neutrophil infiltration in allergic inflammation in rats.
Topics: Animals; Benzoquinones; Furans; Hypersensitivity; Immunization; Inflammation; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1990 |
Release of leukotriene B4 from rat Kupffer cells.
Topics: Animals; Benzoquinones; Calcimycin; Cells, Cultured; Kupffer Cells; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Quinones; Rats; Rats, Inbred Strains; Zymosan | 1989 |
A comparative study on the effects of inhibitors of the lipoxygenase pathway on neutrophil function. Inhibitory effects on neutrophil function may not be attributed to inhibition of the lipoxygenase pathway.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Benzoquinones; Calcimycin; Chemotaxis, Leukocyte; Epoprostenol; Humans; Hydroxides; Hydroxyl Radical; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinones; Tetradecanoylphorbol Acetate; Umbelliferones | 1986 |
The 5-lipoxygenase products can modulate the synthesis of platelet-activating factor (alkyl-acetyl GPC) in Ca-ionophore A23187-stimulated rat peritoneal macrophages.
Topics: Acetophenones; Animals; Arachidonic Acids; Benzoquinones; Calcimycin; Carbon Radioisotopes; Dose-Response Relationship, Drug; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotrienes; Lipid Peroxides; Macrophages; Male; Platelet Activating Factor; Quinones; Rats; Rats, Inbred Strains | 1985 |
Pharmacological studies of platelet-activating factor (PAF)-induced augmentation of response to histamine in guinea-pigs.
Topics: Animals; Benzoquinones; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capillary Permeability; Chromones; Drug Interactions; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Leukocyte Count; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Pressure; Respiratory Physiological Phenomena; Respiratory System; Thromboxane A2 | 1994 |
LTC4/LTB4 alterations in rat forebrain ischemia and reperfusion and effects of AA-861, CV-3988.
Topics: Animals; Benzoquinones; Brain Edema; Brain Ischemia; Injections, Intraperitoneal; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Phospholipid Ethers; Platelet Activating Factor; Premedication; Prosencephalon; Rats; Rats, Wistar; Reperfusion Injury | 1994 |
Pharmacological analysis of neutrophil chemotactic factor production by leucocytes and roles of PAF in allergic inflammation in rats.
Topics: Animals; Azepines; Benzoquinones; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Furans; Hypersensitivity; Immunization; Interleukin-8; Isoelectric Focusing; Leukocytes; Lipoxygenase Inhibitors; Phospholipid Ethers; Platelet Activating Factor; Rats; Triazoles | 1994 |
Platelet-activating factor potentiates protamine-induced lung edema. Role of eicosanoids.
Topics: Animals; Arachidonic Acid; Benzoquinones; Constriction, Pathologic; Drug Synergism; Indomethacin; Leukotriene C4; Lipoxygenase Inhibitors; Male; Organ Size; Platelet Activating Factor; Premedication; Prostaglandins F; Protamines; Pulmonary Circulation; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Thromboxane B2; Vascular Resistance | 1994 |
Protection against platelet-activating factor-induced injury by interferon inducer in perfused rabbit lung.
Topics: Animals; Arachidonic Acids; Benzoquinones; Blood Pressure; Bronchoconstriction; Humans; Hypertension, Pulmonary; In Vitro Techniques; Indicators and Reagents; Indomethacin; Interferon Inducers; Interferon Type I; Lipoxygenase Inhibitors; Lung Diseases; Male; Microcirculation; Platelet Activating Factor; Poly I-C; Pulmonary Edema; Rabbits; Recombinant Proteins; Vascular Resistance | 1993 |
Involvement of nitric oxide and eicosanoids in platelet-activating factor-induced haemodynamic and haematological effects in dogs.
Topics: Animals; Benzoquinones; Biphenyl Compounds; Cell Count; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Eicosanoids; Female; Heptanoic Acids; Hypotension; Indomethacin; Isoquinolines; Lipoxygenase Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Antagonists; Pyridinium Compounds; Tetrahydroisoquinolines; Vascular Resistance | 1996 |
Synergistic effect of type II phospholipase A2 and platelet-activating factor on Mac-1 surface expression and exocytosis of gelatinase granules in human neutrophils: evidence for the 5-lipoxygenase-dependent mechanism.
Topics: Arachidonate 5-Lipoxygenase; Benzoquinones; Calcium; Cytoplasmic Granules; Dose-Response Relationship, Drug; Drug Synergism; Exocytosis; Gelatinases; Humans; Leukotriene B4; Macrophage-1 Antigen; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1998 |
Quinolines attenuate PAF-induced pulmonary pressor responses and edema formation.
Topics: Airway Resistance; Animals; Aspirin; Benzoquinones; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Chloroquine; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Female; Hydrazines; In Vitro Techniques; Interleukin-6; Lipoxygenase Inhibitors; Lung; Male; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Pulmonary Circulation; Pulmonary Edema; Quinidine; Quinine; Quinolines; Rats; Rats, Wistar; Receptors, Thromboxane; Tumor Necrosis Factor-alpha; Vascular Resistance; Vasoconstriction | 1999 |
Leukotriene metabolism by intrapulmonary vessels of newborn lambs: effect of platelet-activating factor.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Benzoquinones; In Vitro Techniques; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular; Platelet Activating Factor; Pulmonary Artery; Pulmonary Veins; Pyridinium Compounds; Sheep | 2001 |