1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with 5-hydroxy-6,8,11,14-eicosatetraenoic acid in 37 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (5-hydroxy-6,8,11,14-eicosatetraenoic acid) | Trials (5-hydroxy-6,8,11,14-eicosatetraenoic acid) | Recent Studies (post-2010) (5-hydroxy-6,8,11,14-eicosatetraenoic acid) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 648 | 5 | 54 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | 5-hydroxy-6,8,11,14-eicosatetraenoic acid (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (37.84) | 18.7374 |
| 1990's | 20 (54.05) | 18.2507 |
| 2000's | 3 (8.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chavis, C; Crastes de Paulet, A; Damon, M; Godard, P; Radeau, T | 1 |
| Dürr, U; Grimminger, F; Seeger, W | 1 |
| Beilin, LJ; Croft, KD; Moulton, C; Proudfoot, J | 1 |
| Aktories, K; Grimminger, F; Seeger, W; Sibelius, U; Suttorp, N | 1 |
| O'Flaherty, JT; Rossi, AG | 2 |
| Catto-Smith, AG; Gall, DG; MacNaughton, WK | 1 |
| Honda, ZI; Ichikawa, Y; Ishii, A; Mike, I; Seyama, Y; Shimizu, T | 1 |
| Franklin-Johnson, J; Kuruvilla, A; Mangus, L; Putcha, G; Schulam, PG; Shearer, WT | 1 |
| Austen, KF; Benincaso, AI; Coblyn, JS; Larkin, JK; Sperling, RI; Weinblatt, ME | 1 |
| Croft, KD; Ysrael, MC | 1 |
| Careaga-Houck, M; Sprecher, H | 1 |
| O'Flaherty, JT; Tessner, TG; Wykle, RL | 1 |
| Heidel, JR; Laegreid, WW; Leid, RW; Liggitt, HD; Silflow, RM; Taylor, SM | 1 |
| Audette, CA; Burstein, SH; Doyle, SA; Hull, K; Hunter, SA; Latham, V | 1 |
| Jacobson, D; O'Flaherty, JT; Redman, J | 1 |
| O'Flaherty, JT | 2 |
| Nishihira, J; O'Flaherty, JT | 1 |
| Parker, CW | 1 |
| O'Flaherty, JT; Redman, J; Samuel, M; Thomas, M; Wykle, RL | 1 |
| O'Flaherty, JT; Rossi, AG; Thomas, MJ | 1 |
| Billah, MM; Bryant, RW; Siegel, MI | 1 |
| McCall, CE; O'Flaherty, JT; Thomas, MJ; Wykle, RL | 1 |
| Carroll, C; Hammett, MJ; McCall, CE; O'Flaherty, JT; Thomas, MJ; Wykle, RL | 1 |
| Chung, D; Gravel, S; Powell, WS | 1 |
| Schröder, JM; Schwenk, U | 1 |
| Kankaanranta, H; Kirkkola, AL; Moilanen, E; Nieminen, MM; Vapaatalo, H | 1 |
| Boyle, T; Gemski, P; Hunt, R; Jett, M; Lancaster, V | 1 |
| Greene, D; O'Flaherty, JT; Redman, JR; Tessner, T; Wykle, RL | 1 |
| Fruchtmann, R; Hatzelmann, A; Mohrs, KH; Müller-Peddinghaus, R; Raddatz, S | 1 |
| Austen, KF; Benincaso, AI; Knoell, CT; Larkin, JK; Robinson, DR; Sperling, RI | 1 |
| Chilton, FH; Hubbard, WC; Sung, CM; Winkler, JD | 1 |
| Grimminger, F; Kiss, L; Mayer, K; Seeger, W; Walmrath, D | 1 |
| Benfield, T; Cowan, MJ; Logun, C; Shelhamer, JH; Tavakoli, S | 1 |
| Beck-Speier, I; Dayal, N; Denzlinger, C; Haberl, C; Heyder, J; Maier, KL; Ziesenis, A | 1 |
3 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and 5-hydroxy-6,8,11,14-eicosatetraenoic acid
| Article | Year |
|---|---|
Bioactions of 5-hydroxyicosatetraenoate and its interaction with platelet-activating factor.
Topics: Animals; Humans; Hydroxyeicosatetraenoic Acids; Platelet Activating Factor; Receptors, Cell Surface | 1991 |
Phospholipid metabolism and stimulus-response coupling.
Topics: Calcium; Cells; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Models, Biological; Phospholipids; Platelet Activating Factor; Protein Kinase C | 1987 |
Lipid mediators produced through the lipoxygenase pathway.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1; Interleukin-2; Leukotriene B4; Lipid Metabolism; Lipoxygenase; Platelet Activating Factor; SRS-A; T-Lymphocytes | 1987 |
34 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and 5-hydroxy-6,8,11,14-eicosatetraenoic acid
| Article | Year |
|---|---|
Enhanced esterification process of 5-hydroxyeicosatetraenoic acid (5-HETE) in PMN from asthmatic patients.
Topics: Adult; Asthma; Calcimycin; Cell Migration Inhibition; Chromatography, High Pressure Liquid; Esterification; Humans; Hydroxyeicosatetraenoic Acids; Middle Aged; Neutrophils; Platelet Activating Factor; Reference Values | 1992 |
Ligand-operated synthesis of 4-series and 5-series leukotrienes in human neutrophils: critical dependence on exogenous free fatty acid supply.
Topics: Calcimycin; Chromatography, High Pressure Liquid; Fatty Acids, Nonesterified; Humans; Hydrolysis; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotrienes; Ligands; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Platelet Activating Factor | 1992 |
The effect of lipoproteins on the release of some eicosanoids by stimulated human leukocytes. A possible role in atherogenesis.
Topics: Arachidonic Acid; Calcimycin; Dextran Sulfate; Dinoprostone; Fatty Acids; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes; Leukotriene B4; Lipoproteins, LDL; Platelet Activating Factor | 1991 |
Inhibition of cytoskeletal rearrangement by botulinum C2 toxin amplifies ligand-evoked lipid mediator generation in human neutrophils.
Topics: Arachidonate 5-Lipoxygenase; Botulinum Toxins; Chemotactic Factors; Chemotaxis, Leukocyte; Cytoskeleton; Eicosanoids; Humans; Hydrolysis; Hydroxyeicosatetraenoic Acids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Phosphatidylinositols; Platelet Activating Factor | 1991 |
A role for phospholipid-derived inflammatory mediators in intestinal anaphylaxis in the rat.
Topics: Anaphylaxis; Animals; Azepines; Biological Transport; Carbazoles; Dinoprostone; Electrolytes; Female; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Jejunum; Leukotriene Antagonists; Leukotrienes; Phospholipids; Platelet Activating Factor; Propionates; Quinolines; Rats; Thromboxanes; Triazoles | 1992 |
The differences in 12-hydroxyeicosatetraenoic acid and thromboxane B2 release from guinea pig platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antibodies; Blood Platelets; Chromatography, High Pressure Liquid; Collagen; Cross Reactions; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Radioimmunoassay; Thromboxane B2 | 1991 |
Platelet-activating factor induces phospholipid turnover, calcium flux, arachidonic acid liberation, eicosanoid generation, and oncogene expression in a human B cell line.
Topics: Arachidonic Acid; Arachidonic Acids; B-Lymphocytes; Calcium; Cell Line, Transformed; DNA-Binding Proteins; Eicosanoids; Gene Expression Regulation; Herpesvirus 4, Human; Humans; Hydroxyeicosatetraenoic Acids; Membrane Lipids; Phospholipids; Phosphorus Radioisotopes; Platelet Activating Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Transcription Factors; Up-Regulation | 1991 |
Inhibition of leukotriene B4 synthesis in neutrophils from patients with rheumatoid arthritis by a single oral dose of methotrexate.
Topics: Aged; Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Calcimycin; Chemotaxis, Leukocyte; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Methotrexate; Middle Aged; Neutrophils; Phospholipases; Platelet Activating Factor | 1990 |
Inhibition of leukotriene and platelet activating factor synthesis in leukocytes by the sesquiterpene lactone scandenolide.
Topics: Animals; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lactones; Leukotriene B4; Plants, Medicinal; Platelet Activating Factor; Rats; Sesquiterpenes; Thromboxane B2 | 1990 |
Effects of a fish oil diet on the metabolism of endogenous (n-6) and (n-3) fatty acids in rat neutrophils.
Topics: Acylation; Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Dietary Fats, Unsaturated; Eicosapentaenoic Acid; Fatty Acids; Fish Oils; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Neutrophils; Phospholipids; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1990 |
Stimulation of platelet-activating factor synthesis by a nonmetabolizable bioactive analog of platelet-activating factor and influence of arachidonic acid metabolites.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetates; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; Hydrolysis; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Phospholipases A; Platelet Activating Factor | 1989 |
Characterization of arachidonic acid metabolism, superoxide production, and bacterial killing in bovine circulating neutrophils and elicited alveolar neutrophils.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Bactericidal Activity; Cattle; Haemophilus; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Neutrophils; Platelet Activating Factor; Pulmonary Alveoli; Staphylococcus epidermidis; Superoxides | 1989 |
Antagonism to the actions of platelet activating factor by a nonpsychoactive cannabinoid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cannabinoids; Dronabinol; Edema; Female; Hydroxyeicosatetraenoic Acids; Mice; Naproxen; Platelet Activating Factor; Structure-Activity Relationship | 1989 |
Mechanism involved in the mobilization of neutrophil calcium by 5-hydroxyeicosatetraenoate.
Topics: Calcium; Cholera Toxin; Cytosol; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Receptors, Prostaglandin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Neutrophil degranulation: evidence pertaining to its mediation by the combined effects of leukotriene B4, platelet-activating factor, and 5-HETE.
Topics: Animals; Calcimycin; Complement C5; Complement C5a; Cytoplasmic Granules; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits | 1985 |
Arachidonate metabolites, platelet-activating factor, and the mobilization of protein kinase C in human polymorphonuclear neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Membrane; Cell-Free System; Cytosol; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Platelet Activating Factor; Protamine Kinase; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Solubility; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1987 |
Metabolism of 5-hydroxyicosatetraenoate by human neutrophils: production of a novel omega-oxidized derivative.
Topics: Calcimycin; Glucuronidase; Humans; Hydroxyeicosatetraenoic Acids; Muramidase; Neutrophils; Oxidation-Reduction; Phospholipids; Platelet Activating Factor; Spectrum Analysis; Triglycerides | 1986 |
Stereospecific bioactions of 5-hydroxyeicosatetraenoate.
Topics: Calcium; Diglycerides; Exocytosis; Glucuronidase; Humans; Hydroxyeicosatetraenoic Acids; Muramidase; Neutrophils; Platelet Activating Factor; Stereoisomerism; Tetradecanoylphorbol Acetate | 1988 |
Lipoxygenase products of arachidonic acid modulate biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) by human neutrophils via phospholipase A2.
Topics: Acetates; Acetic Acid; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Catechols; Humans; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Masoprocol; Membrane Lipids; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Trifluoperazine | 1985 |
[Pathogenicity factors and defense mechanisms in infectious diseases].
Topics: Animals; Arachidonic Acids; Autacoids; Bacterial Infections; Bacterial Toxins; Blood Bactericidal Activity; Female; Gonorrhea; Hemolysin Proteins; Humans; Hydroxyeicosatetraenoic Acids; Immunity, Innate; Immunogenetics; Leukotrienes; Mice; Platelet Activating Factor; Salpingitis | 1984 |
Neutrophil degranulation responses to combinations of arachidonate metabolites and platelet-activating factor.
Topics: Arachidonic Acids; Cytoplasmic Granules; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene A4; Leukotriene B4; Leukotrienes; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1984 |
5-L-hydroxy-6,8,11,14-eicosatetraenoate potentiates the human neutrophil degranulating action of platelet-activating factor.
Topics: Arachidonic Acids; Calcimycin; Complement C5; Complement C5a; Drug Synergism; Glucuronidase; Humans; Hydroxyeicosatetraenoic Acids; Muramidase; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Time Factors | 1983 |
5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration.
Topics: Arachidonic Acid; Arachidonic Acids; Cell Movement; Chemotaxis, Leukocyte; Eosinophils; Glucuronidase; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1995 |
5-Oxo-eicosanoids are potent eosinophil chemotactic factors. Functional characterization and structural requirements.
Topics: Chemotactic Factors; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eicosanoic Acids; Eosinophilia; Eosinophils; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indicators and Reagents; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Structure-Activity Relationship | 1995 |
Interactions between synthesis of platelet-activating factor and leukotriene B4 in isolated human polymorphonuclear leukocytes.
Topics: Arachidonate 5-Lipoxygenase; Azepines; Calcimycin; Chemotaxis, Leukocyte; Drug Interactions; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles | 1993 |
Method for simultaneous isolation and quantitation of platelet activating factor and multiple arachidonate metabolites from small samples: analysis of effects of Staphylococcus aureus enterotoxin B in mice.
Topics: Animals; Arachidonic Acid; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Enterotoxins; Hydroxyeicosatetraenoic Acids; Leukotrienes; Male; Mice; Mice, Inbred ICR; Microchemistry; Platelet Activating Factor; Spectrophotometry; Staphylococcus aureus | 1994 |
Comparison of 1-O-alkyl-, 1-O-alk-1'-enyl-, and 1-O-acyl-2-acetyl-sn-glycero-3-phosphoethanolamines and -3-phosphocholines as agonists of the platelet-activating factor family.
Topics: Animals; Calcium; Cattle; Hydroxyeicosatetraenoic Acids; Neutrophils; Plasmalogens; Platelet Activating Factor; Platelet Activation; Superoxides | 1994 |
Mode of action of the new selective leukotriene synthesis inhibitor BAY X 1005 ((R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl acetic acid) and structurally related compounds.
Topics: Animals; Arachidonic Acid; Binding Sites; Binding, Competitive; Cell-Free System; Humans; Hydroxyeicosatetraenoic Acids; Indoles; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Quinolines; Rats; Structure-Activity Relationship; Subcellular Fractions | 1993 |
Dietary omega-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils.
Topics: Adult; Chemotaxis, Leukocyte; Depression, Chemical; Dietary Fats, Unsaturated; Diglycerides; Fatty Acids; Fatty Acids, Omega-3; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Middle Aged; Monocytes; Neutrophils; Phosphatidylinositols; Platelet Activating Factor | 1993 |
Influence of arachidonic acid on indices of phospholipase A2 activity in the human neutrophil.
Topics: Arachidonic Acid; Calcimycin; Fatty Acids; Fatty Acids, Nonesterified; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotrienes; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1993 |
5-hydroxyicosatetraenoate stimulates neutrophils by a stereospecific, G protein-linked mechanism.
Topics: Calcium; Cells, Cultured; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Tumor Necrosis Factor-alpha | 1993 |
PAF-induced synthesis of tetraenoic and pentaenoic leukotrienes in the isolated rabbit lung.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Capillaries; Cysteine; Drug Combinations; Eicosapentaenoic Acid; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotrienes; Lung; Neutrophils; Platelet Activating Factor; Pulmonary Circulation; Rabbits | 2000 |
Prostaglandin E(2)-induced interleukin-6 release by a human airway epithelial cell line.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bronchi; Cell Line, Transformed; Chemotactic Factors; Dinoprostone; Epithelial Cells; Gene Expression; HeLa Cells; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-6; Leukotriene B4; Platelet Activating Factor; Pneumonia; Respiratory Mucosa; RNA, Messenger | 2001 |
Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2.
Topics: Air Pollutants; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Autoradiography; Carbon Radioisotopes; Cells, Cultured; Chromatography, Thin Layer; Dinoprostone; Dogs; Enzyme Activation; Fatty Acids, Unsaturated; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Macrophages, Alveolar; Phospholipases A; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sulfates; Sulfites; Sulfur; Thromboxane B2 | 2003 |