1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid in 65 studies
Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid) | Trials (15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid) | Recent Studies (post-2010) (15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid) |
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9,156 | 187 | 552 | 2,577 | 27 | 327 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 24 (36.92) | 18.7374 |
1990's | 28 (43.08) | 18.2507 |
2000's | 10 (15.38) | 29.6817 |
2010's | 3 (4.62) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Cattaneo, M; Lecchi, A; Mannucci, PM; McGregor, JL; Randi, AM | 1 |
Babycos, CR; Hood, JS; Ibrahim, IN; Kadowitz, PJ; McMahon, TJ; Nossaman, BD | 1 |
Tatarintsev, AV; Varfolomeyev, SD; Vrzheshch, PV; Yershov, DE | 1 |
Huang, SC; Huang, TF; Li, HL; Teng, CM; Wu, TS | 1 |
Fujii, T; Hashizume, T; Sato, T | 1 |
Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
Arita, H; Hanasaki, K; Kato, T; Kishino, J | 1 |
FitzGerald, GA; Murray, R; Shipp, E | 1 |
Honda, ZI; Ichikawa, Y; Ishii, A; Mike, I; Seyama, Y; Shimizu, T | 1 |
Hellewell, PG; Nourshargh, S; Seale, JP; Williams, TJ | 1 |
Dyson, MC; Kadowitz, PJ | 1 |
Beckerman, RC; Bellan, JA; Braquet, P; Dyson, MC; Kadowitz, PJ; McNamara, DB; Minkes, RK; Wegmann, MJ | 1 |
de Chaffoy de Courcelles, D; De Clerck, F | 1 |
Keery, RJ; Lumley, P | 1 |
Bevan, J; Heptinstall, S | 1 |
Armstead, WM; Busija, DW; Leffler, CW; Mirro, R | 1 |
Baker, RC; Fish, HT; Fitzpatrick, FA | 1 |
Bradley, LM; Czaja, JF; Goldstein, RE; Stambouly, JJ | 1 |
Frojmovic, M; Pedvis, L; Wong, T | 1 |
Davenport, NJ; Ezra, D; Feuerstein, GZ; Goldstein, RE; Laurindo, FR | 1 |
Ashida, Y; Kato, K; Kuriki, H; Matsumoto, T; Shiraishi, M; Terao, S | 1 |
Kadowitz, PJ; Underwood, DC | 1 |
Bradley, LM; Feuerstein, G; Goldstein, RE | 1 |
Daniel, EE; Jury, J; O'Byrne, P; Pashley, M; Serio, R | 1 |
Daniel, EE; Serio, R | 1 |
Esplugues, JV; Whittle, BJ | 1 |
Joseph, S; Kakkar, VV; Krishnamurthi, S | 1 |
Myers, AK; Nakanishi, T; Ramwell, P | 1 |
Mest, HJ; Riedel, A; Schneider, S | 1 |
Armstead, WM; Busija, DW; Leffler, CW; Mirro, R; Pourcyrous, M | 1 |
Lefer, AM; Stahl, GL | 1 |
Malo, PE; Pfeiffer, DF; Wasserman, MA | 1 |
Page, CP; Robertson, DN | 1 |
Altman, R; Rouvier, J; Weisenberger, H | 1 |
Baird, A; Chamberlain, PD; Nunn, B | 1 |
Kakkar, VV; Krishnamurthi, S; Westwick, J | 1 |
Nunn, B | 1 |
Chern, JW; Chou, TC; Ding, YA; Yen, MH | 1 |
Hidaka, T; Ishizuka, T; Kawaguchi, Y; Kawakami, M; Matsuki, Y; Nakamura, H; Suzuki, K | 1 |
Hasegawa, S; Hirata, A; Hirata, F; Lee, JY; Nomura, A; Sakamoto, T; Uchida, Y | 1 |
Hirata, Y; Nakano, M; Nakashima, M; Uematsu, T; Umemura, K | 1 |
Jones, RL; Matthews, JS | 1 |
Heptinstall, S; Lösche, W; Sanderson, HM; Vickers, J | 1 |
Brasch, F; Featherstone, RL; Klein, T; Müller, KM; Nüsing, R; Uhlig, S; Ullrich, V; von Bethmann, A; Wendel, A | 1 |
Hidaka, T; Ishizuka, T; Kawakami, M; Matsuki, Y; Nakamura, H; Suzuki, K | 1 |
Chang, YL; Hsueh, CM; Ko, FN; Lee, SS; Liu, KC; Teng, CM | 1 |
Berend, N; Matheson, MJ; McClean, MA; Rynell, AC | 1 |
Asada, A; Hayashi, M; Inoue, M; Yamada, T; Yukioka, H | 1 |
Akiba, S; Hashizume, T; Kawauchi, T; Oka, T; Sato, T | 1 |
Ariga, T; Kobayashi, A; Kubota, K; Lim, H; Seki, T | 1 |
Held, HD; Martin, C; Uhlig, S | 1 |
Kinlough-Rathbone, RL; Packham, MA; Perry, DW; Rand, ML | 1 |
Ko, FN; Liao, CH; Teng, CM; Wu, CL | 1 |
Gabbeta, J; Kaplan, R; Mao, GF; Rao, AK; Sun, L | 1 |
Calabrese, R; del Basso, P; Fabi, F; Stati, T | 1 |
Heptinstall, S; Newby, LJ; Storey, RF | 1 |
Akkerman, JW; den Dekker, E; Gorter, G; Heemskerk, JW; van der Vuurst, H | 1 |
Gresele, P; Mezzasoma, AM; Venditti, G; Vezza, R | 1 |
Koizumi, T; Kubo, K; Kurata, Y; Ogura, T; Ruan, Z; Shibamoto, T; Shimo, T; Tsuchida, H | 1 |
Chap, H; Fourcade, O; Litt, L; Samii, K; Simon, MF | 1 |
Cui, S; Kurata, Y; Liu, W; Shibamoto, T; Takano, H | 1 |
Fox, SC; Heptinstall, S; White, AE; Wilcox, RG; Xavier, RG | 1 |
Fox, SC; Glenn, JR; Heptinstall, S; Iyú, D; Johnson, AJ; White, AE | 1 |
Fox, SC; Glenn, JR; Heptinstall, S; Iyú, D; Johnson, A; White, AE | 1 |
Brass, LF; Chatterjee, MS; Colace, TV; Diamond, SL; Flamm, MH; Jaeger, D; Jing, H; Sinno, T; Zhou, S | 1 |
1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid
Article | Year |
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Effect of temocillin and moxalactam on platelet responsiveness and bleeding time in normal volunteers.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Bleeding Time; Blood Platelets; Collagen; Humans; Male; Moxalactam; Penicillins; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic | 1985 |
64 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid
Article | Year |
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Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcium; Clot Retraction; Collagen; Cyclic AMP; Epinephrine; Fibrinogen; Hemorrhage; Humans; Indomethacin; Kinetics; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Reference Values; Thrombin; Vasoconstrictor Agents; von Willebrand Factor | 1992 |
Daltroban blocks thromboxane responses in the pulmonary vascular bed of the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Blood Pressure; Cats; Endothelins; Female; Male; Phenylacetates; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Sulfonamides; Thromboxane A2; Vasoconstrictor Agents | 1992 |
Cell response kinetics: the phenomenon of supercooperativity in aggregation of human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Calcimycin; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Tetradecanoylphorbol Acetate; Thimerosal | 1992 |
Antiplatelet actions of some coumarin compounds isolated from plant sources.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Coumarins; Membrane Lipids; Molecular Structure; Phospholipids; Plants; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thrombin; Thromboxane B2 | 1992 |
Sphingosine enhances platelet aggregation through an increase in phospholipase C activity by a protein kinase C-independent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cell Membrane; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Piperazines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rabbits; Sphingosine; Staurosporine; Thrombin; Type C Phospholipases | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
Synergistic effect of thromboxane A2 and N-formylmethionylleucylphenylalanine on platelet-activating factor synthesis in human polymorphonuclear neutrophils.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetyl-CoA C-Acetyltransferase; Binding Sites; Bridged Bicyclo Compounds; Drug Synergism; Fatty Acids, Monounsaturated; Humans; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Thromboxane A2 | 1991 |
Prostaglandin endoperoxide/thromboxane A2 receptor desensitization. Cross-talk with adenylate cyclase in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclases; Cyclic AMP; Down-Regulation; Enzyme Activation; Humans; Iloprost; In Vitro Techniques; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Thromboxane; Thrombin; Thromboxane A2; Type C Phospholipases | 1990 |
The differences in 12-hydroxyeicosatetraenoic acid and thromboxane B2 release from guinea pig platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antibodies; Blood Platelets; Chromatography, High Pressure Liquid; Collagen; Cross Reactions; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Radioimmunoassay; Thromboxane B2 | 1991 |
Mechanism of action of platelet activating factor in the pulmonary circulation: an investigation using a novel isotopic system in rabbit isolated lung.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Proteins; Capillary Permeability; Furans; In Vitro Techniques; Male; Microcirculation; Perfusion; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Pulmonary Edema; Rabbits; Serum Albumin, Radio-Iodinated; Vascular Resistance; Vasoconstriction | 1991 |
Influence of SK&F 96148 on thromboxane-mediated responses in the airways of the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Cats; Endothelins; Endotoxins; Escherichia coli; Female; Male; Phenylacetates; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Respiratory Physiological Phenomena; Respiratory System; Sulfonamides; Thromboxane A2; Thromboxanes | 1991 |
Influence of SK&F 95587 and BN 50730 on bronchoconstrictor responses in the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Azepines; Bronchoconstriction; Cats; Dose-Response Relationship, Drug; Female; Lung; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Receptors, Thromboxane; Respiration; Sulfonamides; Tetrazoles; Thienopyridines; Time Factors; Triazoles | 1990 |
Effect of thromboxane A2 synthetase inhibition, singly and combined with thromboxane A2/prostaglandin endoperoxide receptor antagonism, on inositol phospholipid turnover and on 5-HT release by washed human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Collagen; Humans; In Vitro Techniques; Indomethacin; Inositol Phosphates; Methacrylates; Platelet Activating Factor; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase | 1990 |
AH6809, a prostaglandin DP-receptor blocking drug on human platelets.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Dinoprost; Epoprostenol; Humans; Hydantoins; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Receptors, Immunologic; Receptors, Prostaglandin; Xanthenes; Xanthones | 1988 |
How can we inhibit 5-HT-induced platelet aggregation and why should we bother?
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Amlodipine; Female; Humans; Male; Middle Aged; Nifedipine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Serotonin Antagonists; Verapamil | 1988 |
Permissive role of prostanoids in acetylcholine-induced cerebral vasoconstriction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebrovascular Circulation; Dinoprost; Fatty Acids, Unsaturated; Female; Hydrazines; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Swine; Vasoconstriction | 1989 |
Effects of ethanol on human platelets stimulated with platelet-activating factor, a biologically active ether phospholipid.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Blood Platelets; Ethanol; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thromboxane A2 | 1989 |
Influence of thromboxane A2 receptor antagonism on pulmonary vasoconstrictor responses.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Female; Hemodynamics; Hydrazines; Hypoxia; Lung; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Swine; Thromboxane A2; Vasoconstriction | 1989 |
Platelet size affects both micro- and macro-aggregation: contributions of platelet number, volume fraction and cell surface.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Blood Platelets; Cell Membrane; Cell Separation; Humans; Kinetics; Microscopy, Phase-Contrast; Nephelometry and Turbidimetry; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Prostaglandin Endoperoxides, Synthetic; Ristocetin | 1989 |
Mechanisms of hypotension produced by platelet-activating factor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Female; Hypotension; Indomethacin; Male; Methacrylates; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Swine; Thromboxane A2; Thromboxane-A Synthase | 1989 |
A novel anti-asthmatic quinone derivative, AA-2414 with a potent antagonistic activity against a variety of spasmogenic prostanoids.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Administration, Oral; Animals; Asthma; Benzoquinones; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Histamine Antagonists; Male; Platelet Activating Factor; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Quinones; Rabbits; Rats; Rats, Inbred Strains; SRS-A; Trachea | 1989 |
Analysis of bronchoconstrictor responses to platelet-activating factor in the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Cats; Fatty Acids, Unsaturated; Female; Hydrazines; Lung Compliance; Male; Meclofenamic Acid; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2 | 1989 |
The role of lipid mediators in hypoxic pulmonary vasoconstriction in newborns.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetophenones; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hypoxia; Lipids; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; SRS-A; Swine; Tetrazoles; Thromboxane A2; Vasoconstriction | 1989 |
Effects of inflammatory mediators on neuromuscular transmission in canine trachea in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchial Spasm; Dogs; In Vitro Techniques; Leukotriene B4; Muscle, Smooth; Ozone; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; SRS-A; Synaptic Transmission; Thromboxane A2; Trachea | 1988 |
Thromboxane effects on canine trachealis neuromuscular function.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Fatty Acids, Unsaturated; Female; Hydrazines; In Vitro Techniques; Leukotriene B4; Male; Muscle, Smooth; Neuromuscular Junction; Platelet Activating Factor; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins D; SRS-A; Thromboxane A2; Trachea | 1988 |
Mechanisms contributing to gastric motility changes induced by PAF-acether and endotoxin in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Furans; Gastrointestinal Motility; Male; Platelet Activating Factor; Pressure; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Tetrodotoxin | 1989 |
Effect of phorbol 12-myristate 13-acetate (PMA) on agonist-induced arachidonate release and 5-hydroxytryptamine secretion in human platelets. Dependence of effects on agonist type and time of incubation with PMA.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Humans; In Vitro Techniques; Kinetics; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1987 |
Antagonism of PAF-induced death in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Diterpenes; Epinephrine; Fatty Acids, Unsaturated; Furans; Ginkgolides; Hydrazines; Lactones; Male; Mice; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Pyridines; Thiazoles; Thromboxane A2 | 1988 |
Relevance of eicosanoids for biochemical regulation of cardiac rhythm disturbances.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arrhythmias, Cardiac; Epoprostenol; Fatty Acids, Unsaturated; Guinea Pigs; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Sulfonamides; Thromboxanes | 1987 |
Platelet activating factor: a potent constrictor of cerebral arterioles in newborn pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Arterioles; Cerebrovascular Circulation; Chromones; Dose-Response Relationship, Drug; Norepinephrine; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Reference Values; Swine | 1988 |
Heterogeneity of vascular smooth muscle responsiveness to lipid vasoactive mediators.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cats; Coronary Vessels; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Renal Artery; SRS-A | 1987 |
Enhancement of leukotriene D4-induced contraction of guinea-pig isolated trachea by platelet activating factor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Guinea Pigs; In Vitro Techniques; Male; Meclofenamic Acid; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; SRS-A; Thiazoles; Trachea | 1987 |
Effect of platelet agonists on airway reactivity and intrathoracic platelet accumulation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Female; Guinea Pigs; In Vitro Techniques; Indium Radioisotopes; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Respiratory System | 1987 |
Identification of platelet inhibitor present in the melon (Cucurbitacea cucumis melo).
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Collagen; Epinephrine; Fruit; Humans; Kinetics; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thrombin | 1985 |
Regulation of human platelet activation--analysis of cyclooxygenase and cyclic AMP-dependent pathways.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Serotonin; Thrombin; Thromboxane B2 | 1984 |
Total and selective desensitisation of human platelets to synthetic platelet activating factor (PAF): evidence that extracellular PAF does not mediate collagen-induced aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aspirin; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Extracellular Space; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic | 1983 |
Antiplatelet actions of 2-(4-[1-(2-chlorophenyl) piperazinyl]) methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one compound.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Cyclic AMP; Epinephrine; Fibrinogen; Humans; Imidazoles; Pancreatic Elastase; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Quinazolines; Rabbits; Receptors, Cell Surface; Signal Transduction; Thromboxane A2; Thromboxane B2 | 1995 |
DP-1904, a specific inhibitor of thromboxane A2 synthesizing enzyme, suppresses ICAM-1 expression by stimulated vascular endothelial cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Cell Division; Cells, Cultured; Cycloheximide; Endothelium, Vascular; Epoprostenol; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-1; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Recombinant Proteins; Tetrahydronaphthalenes; Thrombin; Thromboxane A2; Thromboxane-A Synthase; Tumor Necrosis Factor-alpha; Umbilical Veins | 1994 |
IL-1 beta regulates the expression of the Gi2 alpha gene via lipid mediators in guinea pig tracheal muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Gene Expression Regulation; GTP-Binding Proteins; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Interleukin-1; Leukotriene D4; Lipids; Lipoxygenase Inhibitors; Masoprocol; Muscle, Smooth; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Recombinant Proteins; Thromboxane A2; Trachea; Vasoconstrictor Agents | 1994 |
Enhancement of thrombotic arterial occlusion following cholesterol feeding in the guinea-pig: a role for thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arterial Occlusive Diseases; Cholesterol, Dietary; Collagen; Femoral Artery; Guinea Pigs; Male; Photochemistry; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thrombosis; Thromboxane A2; Time Factors | 1994 |
Potentiation of aggregation and inhibition of adenylate cyclase in human platelets by prostaglandin E analogues.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Dinoprostone; Drug Synergism; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E, Synthetic; Xanthenes; Xanthones | 1993 |
Studies on the effects of agonists and antagonists on platelet shape change and platelet aggregation in whole blood.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Azepines; Blood Platelets; Humans; In Vitro Techniques; Piperazines; Piperidines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Serotonin; Succinates; Sulfonamides; Thromboxane A2; Triazoles; Vasoconstrictor Agents | 1996 |
Cyclooxygenase-2-dependent bronchoconstriction in perfused rat lungs exposed to endotoxin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Bronchoconstriction; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA Primers; Endotoxins; Female; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Lipoxygenase Inhibitors; Lung; Microscopy, Electron, Scanning; Platelet Activating Factor; Polymerase Chain Reaction; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Salmonella; Thromboxane A2; Thromboxane B2; Transcription, Genetic; Vasoconstrictor Agents | 1996 |
Thromboxane A2 receptor blockade suppresses intercellular adhesion molecule-1 expression by stimulated vascular endothelial cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Humans; Hydrazines; Intercellular Adhesion Molecule-1; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Protein Kinase Inhibitors; Protein Kinases; Radioligand Assay; Receptors, Thromboxane; Thromboxane A2; Tumor Necrosis Factor-alpha | 1996 |
Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aporphines; Arachidonic Acid; Blood Platelets; Collagen; Cyclic AMP; Guaiacol; Humans; Isoquinolines; Isotope Labeling; Lipoxygenase Inhibitors; Male; Phenanthrenes; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinolines; Rabbits; Radioimmunoassay; Structure-Activity Relationship; Thrombin; Thromboxane B2; Vasoconstrictor Agents | 1997 |
Role of platelet activating factor, leukotrienes and polymorphs in the FMLP induced increase in microvascular leakage in rabbit trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkylating Agents; Animals; Azepines; Bronchitis; Capillary Permeability; Coloring Agents; Disease Models, Animal; Drug Interactions; Evans Blue; Indazoles; Leukotrienes; Male; Mechlorethamine; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rabbits; Reference Values; Trachea; Triazoles; Vasoconstrictor Agents | 1997 |
Effects of inhaled nitric oxide on platelet-activating factor-induced pulmonary hypertension in dogs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Hemoglobins; Hypertension, Pulmonary; Injections, Intravenous; Methemoglobin; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxygen; Platelet Activating Factor; Pulmonary Circulation; Vasoconstrictor Agents | 1998 |
Inhibitory effect of the leaf extract of Ginkgo biloba L. on oxidative stress-induced platelet aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Collagen; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Ginkgo biloba; Ginkgolides; In Vitro Techniques; Iron; Kinetics; Lactones; Oxidative Stress; Plant Extracts; Plant Leaves; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; tert-Butylhydroperoxide; Thrombin | 1998 |
Inhibitory effect of sulfur-containing compounds in Scorodocarpus borneensis Becc. on the aggregation of rabbit platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Coagulation Factors; Collagen; Hemostatics; Hexanes; Inhibitory Concentration 50; Octanes; Plant Extracts; Plants, Edible; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Sulfur Compounds; Thrombin; Trees; Vasoconstrictor Agents | 1999 |
Characterization of airway and vascular responses in murine lungs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Animals; Bombesin; Bronchoconstriction; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Endothelin-1; Female; Histidine; In Vitro Techniques; Leukotriene C4; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Perfusion; Platelet Activating Factor; Serotonin; Substance P; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Effects of cathepsin G pretreatment of platelets on their subsequent responses to aggregating agents.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Anti-Bacterial Agents; Blood Platelets; Cathepsin G; Cathepsins; Drug Interactions; Hemostatics; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Ristocetin; Serine Endopeptidases; Serotonin; Thrombin; Vasoconstrictor Agents | 1999 |
Antiplatelet effect of marchantinquinone, isolated from Reboulia hemisphaerica, in rabbit washed platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Arachidonic Acid; Bibenzyls; Blood Platelets; Calcium; Collagen; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Ethers, Cyclic; Phosphatidylinositols; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thromboxane B2 | 2000 |
Combined defect in membrane expression and activation of platelet GPIIb--IIIa complex without primary sequence abnormalities in myeloproliferative disease.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aged; Antibodies, Monoclonal; Binding Sites; Blood Platelets; Calcimycin; Diglycerides; DNA, Complementary; Enzyme Activators; Flow Cytometry; Humans; Immunoblotting; Intercellular Signaling Peptides and Proteins; Ionophores; Macrophage-1 Antigen; Male; Myeloproliferative Disorders; Neutrophils; Peptides; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymerase Chain Reaction; Protein Binding; Protein Kinase C; Receptors, Thrombin; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Signal Transduction | 2000 |
Nitric oxide (NO) modulation of PAF-induced cardiopulmonary action: interaction between NO synthase and cyclo-oxygenase-2 pathways.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Arginine; Blood Pressure; Cardiac Output; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Rate; Histamine; Indomethacin; Isoenzymes; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitrobenzenes; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pulmonary Ventilation; Serotonin; Signal Transduction; Sulfonamides | 2001 |
Effects of P2Y(1) and P2Y(12) receptor antagonists on platelet aggregation induced by different agonists in human whole blood.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Collagen; Epinephrine; Humans; Membrane Proteins; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Proteins; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Thrombin; Serotonin; Streptokinase | 2001 |
Biogenesis of G-protein mediated calcium signaling in human megakaryocytes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Calcium Signaling; Cattle; Cell Differentiation; Cells, Cultured; Fetal Blood; Flow Cytometry; Gene Expression Regulation, Developmental; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Iloprost; Megakaryocytes; Platelet Activating Factor; Protein Isoforms; Proto-Oncogene Proteins; Stem Cells; Thrombin; Thrombopoietin | 2001 |
Prostaglandin endoperoxides and thromboxane A2 activate the same receptor isoforms in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Biphenyl Compounds; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Fatty Acids, Unsaturated; Heptanoic Acids; Humans; Hydrazines; Imidazoles; Inositol Phosphates; Kidney; Methacrylates; Phenylacetates; Platelet Activating Factor; Platelet Activation; Prostaglandin H2; Prostaglandins H; Protein Isoforms; Receptors, Thromboxane; Recombinant Fusion Proteins; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 2002 |
Effects of platelet-activating factor and thromboxane A2 on isolated perfused guinea pig liver.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bile; Capillary Permeability; Guinea Pigs; In Vitro Techniques; Infusion Pumps; Liver; Liver Circulation; Liver Diseases; Male; Organ Size; Platelet Activating Factor; Portal Vein; Reperfusion Injury; Thromboxane A2; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Propofol inhibits human platelet aggregation induced by proinflammatory lipid mediators.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anesthetics, Intravenous; Blood Platelets; Calcium; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Inflammation Mediators; Lysophospholipids; Platelet Activating Factor; Platelet Aggregation; Propofol; Receptors, Cell Surface; Thromboxane A2 | 2004 |
Effects of platelet-activating factor, thromboxane A2 and leukotriene D4 on isolated perfused rat liver.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Hemodynamics; In Vitro Techniques; Leukotriene D4; Liver; Male; Organ Size; Oxygen Consumption; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstriction | 2006 |
Enhanced platelet aggregation and activation under conditions of hypothermia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Monophosphate; Anticoagulants; Antigens, CD; Aspirin; Blood Platelets; Blood Specimen Collection; Citrates; Cold Temperature; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hirudins; Humans; Hypothermia, Induced; In Vitro Techniques; P-Selectin; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Platelet Membrane Glycoproteins; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Receptors, Thrombin; Tetraspanin 30; Time Factors | 2007 |
The role of prostanoid receptors in mediating the effects of PGE(2) on human platelet function.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Calcium Signaling; Cell Adhesion Molecules; Cyclic AMP; Dinoprostone; Humans; Microfilament Proteins; Naphthalenes; Oligopeptides; P-Selectin; Phenylbutyrates; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype | 2010 |
The role of prostanoid receptors in mediating the effects of PGE3 on human platelet function.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Atherosclerosis; Blood Platelets; Cardiovascular System; Dose-Response Relationship, Drug; Humans; P-Selectin; Platelet Activating Factor; Platelet Aggregation; Receptors, Prostaglandin E | 2012 |
Multiscale prediction of patient-specific platelet function under flow.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Calcium; Crotalid Venoms; HEK293 Cells; Humans; Lectins, C-Type; Male; Microfluidic Analytical Techniques; Models, Biological; Platelet Activating Factor; Platelet Function Tests; Predictive Value of Tests; Receptors, Thromboxane; Reference Values; Signal Transduction; Thrombosis; Vasoconstrictor Agents | 2012 |