Compounds > 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and 1-anilino-8-naphthalenesulfonate

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with 1-anilino-8-naphthalenesulfonate in 17 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)		Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)		Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)		Studies
(1-anilino-8-naphthalenesulfonate)		Trials
(1-anilino-8-naphthalenesulfonate)		Recent Studies (post-2010) (1-anilino-8-naphthalenesulfonate)
9,15618755224,2754807,815

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)1-anilino-8-naphthalenesulfonate (IC50)
Chain A, RNA-directed RNA polymerase NS5Dengue virus 2 16681-PDK53100
Mitogen-activated protein kinase 14Homo sapiens (human)1.2

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's12 (70.59)18.2507
2000's3 (17.65)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Achiwa, K; Ebiike, H; Maruyama, K1
Ganong, BR1
Goto, T; Hibino, A; Mimura, K; Mori, Y; Mune, M; Nishikawa, O; Nomoto, H; Okada, K; Sonobe, M; Yukawa, S1
Blank, ML; Cress, EA; Smith, ZL; Snyder, F1
Benveniste, J; Chignard, M; Lefort, J; Vargaftig, BB; Wal, F1
Formela, LJ; Galloway, SW; Kingsnorth, AN1
Hirano, T; Imamura, T; Kyogoku, T; Manabe, T; Ohshio, G; Yamamoto, M; Yoshitomi, S; Yotsumoto, F1
Chapman, MJ; Dentan, C; Lesnik, P; Ninio, E1
Braquet, P; Gukovskaya, A; Gukovsky, S; Pandol, SJ; Poucell-Hatton, S; Reavey, P; Sandoval, D; Sisk, A1
Closa, D; Gelpí, E; Hotter, G; Pi, F; Prats, N; Roselló-Catafau, J1
Carter, G; Denham, D; Denham, W; Fink, G; Norman, J; Ward, K; Yang, J1
Aoki, J; Arai, H; Castro, C; Derewenda, U; Derewenda, ZS; Inoue, K; Minor, W; Servin-Gonzalez, L; Swenson, L; Wei, Y1
Andersson, R; Deng, X; Ihse, I; Soltesz, V; Sun, Z; Wang, X1
Closa, D; Folch, E; Gelpí, E; Panés, J; Piqué, JM; Prats, N; Roselló-Catafau, J; Salas, A1
Huseyinov, A; Ozutemiz, O; Saruc, M; Turkel, N; Tuzcuoglu, I; Yuce, G; Yuceyar, H1
Bukhave, K; Harkewicz, R; Hartvigsen, K; Hølmera, G; Kamido, H; Kuksis, A; Ravandi, A1
Ajandouz, el H; Bouza, B; Fontbonne, H; Lombardo, D; Puigserver, A1

Reviews

2 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and 1-anilino-8-naphthalenesulfonate

ArticleYear
Roles of lipid turnover in transmembrane signal transduction.
    The American journal of the medical sciences, 1991, Volume: 302, Issue:5

    Topics: Animals; Eicosanoids; Humans; Lipase; Membrane Lipids; Phosphatidylcholines; Phosphatidylinositols; Phospholipases; Platelet Activating Factor; Second Messenger Systems; Signal Transduction; Sphingolipids

1991
Background and present status of research on platelet-activating factor (PAF-acether).
    Annals of the New York Academy of Sciences, 1981, Volume: 370

    Topics: Animals; Basophils; Blood Platelets; Chromatography, Thin Layer; Dogs; Guinea Pigs; Humans; Leukocytes; Lipase; Lysophosphatidylcholines; Macrophages; Neutrophils; Phospholipases A; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Sulfinpyrazone

1981

Trials

1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and 1-anilino-8-naphthalenesulfonate

ArticleYear
Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis.
    The British journal of surgery, 1995, Volume: 82, Issue:10

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amylases; C-Reactive Protein; Double-Blind Method; E-Selectin; Female; Humans; Interleukin-6; Interleukin-8; Lipase; Male; Middle Aged; Pancreatitis; Platelet Activating Factor

1995

Other Studies

14 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and 1-anilino-8-naphthalenesulfonate

ArticleYear
Lipase-catalyzed enantioselective hydrolysis of 4-alkyl-1,4-dihydropyridine derivatives: synthesis of (+)- and (-)-methyl 2-(phenylthio)ethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (PCA 4248).
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:4

    Topics: Dihydropyridines; Hydrolysis; Lipase; Platelet Activating Factor; Stereoisomerism

1992
Effect of platelet-activating factor on lipoprotein lipase and blood lipids.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Cholesterol; Kinetics; Lipase; Lipids; Lipolysis; Lipoprotein Lipase; Male; Phospholipids; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Reference Values; Triglycerides

1991
Characterization of the enzymatic hydrolysis of acetate from alkylacetylglycerols in the de novo pathway of PAF biosynthesis.
    Biochimica et biophysica acta, 1990, Feb-06, Volume: 1042, Issue:2

    Topics: Acetates; Animals; Blood Platelets; Carcinoma, Ehrlich Tumor; Cells, Cultured; Hydrolysis; Lipase; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Sodium Fluoride; Tumor Cells, Cultured

1990
Platelet-activating factor involvement in the aggravation of acute pancreatitis in rabbits.
    Digestion, 1994, Volume: 55, Issue:4

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Hemodynamics; Lipase; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rabbits

1994
Phagocytic activation induces formation of platelet-activating factor in human monocyte-derived macrophages and in macrophage-derived foam cells. Relevance to the inflammatory reaction in atherogenesis.
    European journal of biochemistry, 1996, Feb-15, Volume: 236, Issue:1

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Arteriosclerosis; Cells, Cultured; Foam Cells; Humans; Inflammation; Lipase; Macrophage Activation; Macrophages; Monocytes; Opsonin Proteins; Phagocytosis; Phospholipases A; Platelet Activating Factor; Zymosan

1996
The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis.
    Gastroenterology, 1996, Volume: 111, Issue:4

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Diterpenes; Ginkgolides; Lactones; Lipase; Male; Neutrophils; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

1996
Free radical enhancement promotes leucocyte recruitment through a PAF and LTB4 dependent mechanism.
    Free radical biology & medicine, 1997, Volume: 22, Issue:6

    Topics: Animals; Diterpenes; Free Radicals; Ginkgolides; Indoles; Lactones; Leukotriene B4; Lipase; Male; Neutrophils; Pancreas; Pancreatitis; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines

1997
Gene targeting demonstrates additive detrimental effects of interleukin 1 and tumor necrosis factor during pancreatitis.
    Gastroenterology, 1997, Volume: 113, Issue:5

    Topics: Amylases; Animals; Gene Targeting; Interleukin-1; Interleukin-6; Lipase; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatitis; Platelet Activating Factor; Receptors, Interleukin-1; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha

1997
Structure of a microbial homologue of mammalian platelet-activating factor acetylhydrolases: Streptomyces exfoliatus lipase at 1.9 A resolution.
    Structure (London, England : 1993), 1998, Apr-15, Volume: 6, Issue:4

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Fungal Proteins; Hydrogen Bonding; Lipase; Models, Molecular; Molecular Sequence Data; Phospholipases A; Platelet Activating Factor; Protein Structure, Secondary; Sequence Alignment; Streptomyces; Structure-Activity Relationship

1998
Effect of a platelet-activating factor antagonist on pancreatitis-associated gut barrier dysfunction in rats.
    Pancreas, 1998, Volume: 17, Issue:2

    Topics: Acute Disease; Animals; Bacterial Translocation; Calcium; Capillary Permeability; Endothelium, Vascular; Enterobacteriaceae; Hematocrit; Imidazoles; Intestinal Mucosa; Leucine; Lipase; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Taurodeoxycholic Acid

1998
H(2)O(2) and PARS mediate lung P-selectin upregulation in acute pancreatitis.
    Free radical biology & medicine, 2000, Apr-15, Volume: 28, Issue:8

    Topics: Acute Disease; Amylases; Animals; Benzamides; Catalase; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation; Hydrogen Peroxide; Lipase; Lung; Male; P-Selectin; Pancreatitis; Peroxidase; Platelet Activating Factor; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Respiratory Distress Syndrome; Superoxide Dismutase; Taurocholic Acid; Xanthine Oxidase

2000
An experimental model of hemolysis-induced acute pancreatitis.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2003, Volume: 36, Issue:7

    Topics: Acute Disease; Amylases; Anemia, Hemolytic; Animals; Disease Models, Animal; Hemolysis; Lipase; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2003
1 -O-alkyl-2-(omega-oxo)acyl-sn-glycerols from shark oil and human milk fat are potential precursors of PAF mimics and GHB.
    Lipids, 2006, Volume: 41, Issue:7

    Topics: Aldehydes; Animals; Biotransformation; Fish Oils; Glycerides; Humans; Lipase; Milk, Human; Molecular Structure; Platelet Activating Factor; Sharks; Sodium Oxybate; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism

2006
Activation of bile salt dependent lipase by (lyso)phosphatidic acid and platelet activating factor.
    FEBS letters, 2013, Sep-17, Volume: 587, Issue:18

    Topics: Binding Sites; Enzyme Activation; Enzyme Assays; Female; Humans; Kinetics; Lipase; Lysophosphatidylcholines; Lysophospholipids; Milk, Human; Phosphatidic Acids; Phosphatidylcholines; Platelet Activating Factor; Protein Binding; Taurocholic Acid

2013