Page last updated: 2024-09-04

1-ethynylpyrene and benzo(a)pyrene

1-ethynylpyrene has been researched along with benzo(a)pyrene in 4 studies

Compound Research Comparison

Studies
(1-ethynylpyrene)
Trials
(1-ethynylpyrene)
Recent Studies (post-2010)
(1-ethynylpyrene)
Studies
(benzo(a)pyrene)
Trials
(benzo(a)pyrene)
Recent Studies (post-2010) (benzo(a)pyrene)
22027,311172,154

Protein Interaction Comparison

ProteinTaxonomy1-ethynylpyrene (IC50)benzo(a)pyrene (IC50)
Cytochrome P450 1A2Homo sapiens (human)0.04
Amine oxidase [flavin-containing] AHomo sapiens (human)5.972

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alworth, WL; Sandoval, A; Slaga, TJ; Viaje, A; Warren, BS1
Alworth, WL; DiGiovanni, J; Hopkins, NE; Lu, JY; Nettikumara, AN; Slaga, TJ; Viaje, A1
Alworth, WL; Grover, PL; Hall, M; Hopkins, NE; Lu, JY; Parker, DK1
Acebo, AL; Alworth, WL; Gan, LS1

Other Studies

4 other study(ies) available for 1-ethynylpyrene and benzo(a)pyrene

ArticleYear
Potent inhibitory effects of suicide inhibitors of P450 isozymes on 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene initiated skin tumors.
    Carcinogenesis, 1991, Volume: 12, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme Inhibitors; DNA; Dose-Response Relationship, Drug; Isoenzymes; Mice; Naphthalenes; Polychlorinated Dibenzodioxins; Pyrenes; Skin Neoplasms

1991
Inhibition of the binding of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene to DNA in mouse skin epidermis by 1-ethynylpyrene.
    Carcinogenesis, 1990, Volume: 11, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; DNA; Dose-Response Relationship, Drug; Mice; Naphthalenes; Pyrenes; Skin

1990
Effects of 1-ethynylpyrene and related inhibitors of P450 isozymes upon benzo[a]pyrene metabolism by liver microsomes.
    Chemico-biological interactions, 1990, Volume: 76, Issue:2

    Topics: Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Naphthalenes; Perylene; Pyrenes; Rats; Rats, Inbred Strains

1990
1-Ethynylpyrene, a suicide inhibitor of cytochrome P-450 dependent benzo[a]pyrene hydroxylase activity in liver microsomes.
    Biochemistry, 1984, Aug-14, Volume: 23, Issue:17

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrene Hydroxylase; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Kinetics; Male; Microsomes, Liver; NADP; Phenobarbital; Pyrenes; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence

1984