1-ethynylpyrene has been researched along with alpha-naphthoflavone in 4 studies
| Studies (1-ethynylpyrene) | Trials (1-ethynylpyrene) | Recent Studies (post-2010) (1-ethynylpyrene) | Studies (alpha-naphthoflavone) | Trials (alpha-naphthoflavone) | Recent Studies (post-2010) (alpha-naphthoflavone) |
|---|---|---|---|---|---|
| 22 | 0 | 2 | 665 | 1 | 142 |
| Protein | Taxonomy | 1-ethynylpyrene (IC50) | alpha-naphthoflavone (IC50) |
|---|---|---|---|
| Carboxylic ester hydrolase | Sus scrofa (pig) | 0.0478 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 2.3034 | |
| Cytochrome P450 1A1 | Homo sapiens (human) | 0.1921 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.1698 | |
| Aromatase | Homo sapiens (human) | 1.035 | |
| Substance-K receptor | Homo sapiens (human) | 5.8471 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.01 | |
| Thromboxane-A synthase | Homo sapiens (human) | 6.7608 | |
| Adenosine receptor A1 | Homo sapiens (human) | 1.1325 | |
| Aryl hydrocarbon receptor | Mus musculus (house mouse) | 0.025 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.05 | |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | 4.98 | |
| Cytochrome P450 1B1 | Homo sapiens (human) | 0.0449 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 1.355 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Dasmahaptra, AK; Lee, PC | 1 |
| Annas, A; Brittebo, EB; Granberg, AL | 1 |
| Brandt, I; Granberg, L; Lindhe, O | 1 |
1 review(s) available for 1-ethynylpyrene and alpha-naphthoflavone
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
3 other study(ies) available for 1-ethynylpyrene and alpha-naphthoflavone
| Article | Year |
|---|---|
Interaction of 1-ethynylpyrene and hepatic CYPIA1 from rainbow trout.
Topics: Analysis of Variance; Animals; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Kinetics; Liver; Microsomes, Liver; Oncorhynchus mykiss; Oxidoreductases; Pyrenes; Rats | 1994 |
Differential response of cultured human umbilical vein and artery endothelial cells to Ah receptor agonist treatment: CYP-dependent activation of food and environmental mutagens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Carbolines; Cells, Cultured; Cytochrome P-450 CYP1A1; Endothelium, Vascular; Environmental Pollutants; Enzyme Induction; Enzyme Inhibitors; Food Supply; Humans; Infant, Newborn; Miconazole; Mutagens; Pyrenes; Tritium; Umbilical Arteries; Umbilical Veins | 2000 |
Target cells for cytochrome p450-catalysed irreversible binding of 7,12-dimethylbenz[a]anthracene (DMBA) in rodent adrenal glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex; Animals; Aryl Hydrocarbon Hydroxylases; Autoradiography; Benzoflavones; Binding Sites; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Ellipticines; Endothelium; Enzyme Inhibitors; Female; Mice; Mice, Inbred Strains; Polychlorinated Biphenyls; Pyrenes; Rats; Rats, Sprague-Dawley; Zona Glomerulosa; Zona Reticularis | 2002 |