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1-ethyl-2-methyl-3-hydroxypyridin-4-one and 1-methyl-2-ethyl-3-hydroxypyridin-4-one

1-ethyl-2-methyl-3-hydroxypyridin-4-one has been researched along with 1-methyl-2-ethyl-3-hydroxypyridin-4-one in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
el-Jammal, A; Howell, PL; Li, N; Templeton, DM; Turner, MA1
Dobbin, PS; Hall, AD; Hider, RC; Porter, JB; Sarpong, P; Taylor, PD; van der Helm, D; Xiao, G1
Dekhordi, LS; Hider, RC; Jin, Y; Khodr, H; Liu, Z; Rai, BL1
Hider, RC; Kayyali, R; Liu, ZD; Porter, JB; Theobald, AE1
Cohen, SM; Fullagar, JL; Jacobsen, JA; Miller, MT1
Caisová, D; Eybl, V; Kontoghiorghes, GJ; Koutenský, J1

Other Studies

6 other study(ies) available for 1-ethyl-2-methyl-3-hydroxypyridin-4-one and 1-methyl-2-ethyl-3-hydroxypyridin-4-one

ArticleYear
Copper complexation by 3-hydroxypyridin-4-one iron chelators: structural and iron competition studies.
    Journal of medicinal chemistry, 1994, Feb-18, Volume: 37, Issue:4

    Topics: Antithyroid Agents; Copper; Deferiprone; Iron Chelating Agents; Ligands; Potentiometry; Pyridones; Spectrophotometry

1994
Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential.
    Journal of medicinal chemistry, 1993, Aug-20, Volume: 36, Issue:17

    Topics: Administration, Oral; Animals; Crystallography; Deferoxamine; Horses; Humans; Iron; Iron Chelating Agents; Liver; Mice; Pyridones; Rats; Stereoisomerism; Structure-Activity Relationship

1993
Synthesis, physicochemical properties, and evaluation of N-substituted-2-alkyl-3-hydroxy-4(1H)-pyridinones.
    Journal of medicinal chemistry, 1998, Aug-27, Volume: 41, Issue:18

    Topics: Animals; Bile; Ferritins; Iron; Iron Chelating Agents; Male; Molecular Conformation; Pyridones; Rats; Rats, Inbred F344; Solutions; Structure-Activity Relationship

1998
Design, synthesis, and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones: structure-activity investigation of metalloenzyme inhibition by iron chelators.
    Journal of medicinal chemistry, 2002, Jan-31, Volume: 45, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Enzyme Inhibitors; Iron; Iron Chelating Agents; Lipoxygenase Inhibitors; Male; Pyridines; Pyridones; Rats; Rats, Wistar; Structure-Activity Relationship

2002
Identifying chelators for metalloprotein inhibitors using a fragment-based approach.
    Journal of medicinal chemistry, 2011, Jan-27, Volume: 54, Issue:2

    Topics: Antigens, Bacterial; Bacterial Toxins; Chelating Agents; Copper; Drug Design; Humans; Hydroxyquinolines; Iron; Ligands; Lipoxygenase Inhibitors; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Monophenol Monooxygenase; Nitric Oxide Synthase Type II; Recombinant Proteins; Small Molecule Libraries; Structure-Activity Relationship; Sulfonamides; Zinc

2011
Influence of iron chelators, 1,2-dialkyl-3-hydroxypyridin-4-ones, on the lipid peroxidation and glutathione level in the liver of mice.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1991, Volume: 14

    Topics: Animals; Cadmium; Carbon Tetrachloride; Deferiprone; Glutathione; In Vitro Techniques; Indium; Iron; Iron Chelating Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Pyridones

1991