Page last updated: 2024-08-23

1-deoxynojirimycin and sucrose

1-deoxynojirimycin has been researched along with sucrose in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's4 (36.36)18.2507
2000's1 (9.09)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Creutzfeldt, W; Ebert, R; Fölsch, UR; Gatzemeier, W; Lembcke, B; Siegel, E1
Creutzfeldt, W; Ebert, R; Fölsch, UR; Gatzemeier, W; Lembcke, B; Lücke, B; Siegel, E1
Madar, Z1
Cauderay, M; Felber, JP; Hillebrand, I; Jéquier, E; Tappy, L; Temler, E1
Barker, HM; Bowey, EA; Canfield, JE; Taylor, RH1
Gradnig, G; Legler, G; Stütz, AE1
Bowen, WH; Wunder, D1
Dwek, RA; Lloyd-Evans, E; Neville, DC; Platt, FM; Sillence, DJ; te Vruchte, D; van Blitterswijk, WJ; Veldman, RJ1
Aghajari, N; Haser, R; Lipski, A; Mattes, R; Ravaud, S; Rhimi, M; Robert, X; Watzlawick, H1
Goda, T; Harazaki, T; Imai, C; Inoue, S; Mochizuki, K1
Chen, J; Dong, LC; Fan, YX; He, JC; Wu, JL; Yu, CJ; Zhang, J; Zhang, P; Zhang, XP; Zhao, MX; Zhou, MD; Zhu, FJ1

Trials

4 trial(s) available for 1-deoxynojirimycin and sucrose

ArticleYear
Inhibition of glycemic and hormonal responses after repetitive sucrose and starch loads by different doses of the alpha-glucosidase inhibitor miglitol (BAY m 1099) in man.
    Pharmacology, 1991, Volume: 43, Issue:6

    Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Dietary Carbohydrates; Double-Blind Method; Gastric Inhibitory Polypeptide; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Male; Starch; Sucrose

1991
Inhibition of sucrose- and starch-induced glycaemic and hormonal responses by the alpha-glucosidase inhibitor emiglitate (BAY o 1248) in healthy volunteers.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:6

    Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Breath Tests; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Gastric Inhibitory Polypeptide; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hydrogen; Insulin; Male; Starch; Sucrose

1991
Effect of alpha-glycohydrolase inhibitors (Bay m1099 and Bay o1248) on sucrose metabolism in normal men.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:5

    Topics: 1-Deoxynojirimycin; Administration, Oral; Adult; Blood Glucose; Breath Tests; Fatty Acids, Nonesterified; Glucosamine; Humans; Hydrogen; Imino Pyranoses; Insulin; Lipids; Male; Pulmonary Gas Exchange; Sucrose

1986
Bioequivalence Study of Miglitol Orally Disintegrating Tablets in Healthy Chinese Volunteers Under Fasting Condition Based on Pharmacodynamic and Pharmacokinetic Parameters.
    Clinical pharmacology in drug development, 2023, Volume: 12, Issue:11

    Topics: 1-Deoxynojirimycin; Area Under Curve; East Asian People; Fasting; Healthy Volunteers; Humans; Sucrose; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency

2023

Other Studies

7 other study(ies) available for 1-deoxynojirimycin and sucrose

ArticleYear
Metabolic consequences of the alpha-glucosidase inhibitor BAY-M-1099 given to nondiabetic and diabetic rats fed a high-carbohydrate diet.
    The American journal of clinical nutrition, 1989, Volume: 49, Issue:1

    Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diet; Dietary Carbohydrates; Glucosamine; Glycoside Hydrolase Inhibitors; Glycosuria; Imino Pyranoses; Male; Rats; Rats, Inbred Strains; Sucrose; Triglycerides

1989
Regulation of the absorption of dietary carbohydrate in man by two new glycosidase inhibitors.
    Gut, 1986, Volume: 27, Issue:12

    Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Dietary Carbohydrates; Dose-Response Relationship, Drug; Glucosamine; Glycoside Hydrolases; Humans; Hydrogen; Imino Pyranoses; Intestinal Absorption; Male; Maltose; Starch; Substrate Specificity; Sucrose

1986
A novel approach to the 1-deoxynojirimycin system: synthesis from sucrose of 2-acetamido-1, 2-dideoxynojirimycin, as well as some 2-N-modified derivatives.
    Carbohydrate research, 1996, Jun-07, Volume: 287, Issue:1

    Topics: 1-Deoxynojirimycin; Animals; Cattle; Enzyme Inhibitors; Fabaceae; Hexosaminidases; Kidney; Molecular Structure; Plants, Medicinal; Snails; Sucrose

1996
Action of agents on glucosyltransferases from Streptococcus mutans in solution and adsorbed to experimental pellicle.
    Archives of oral biology, 1999, Volume: 44, Issue:3

    Topics: 1-Deoxynojirimycin; Adsorption; Bacterial Proteins; Cations, Monovalent; Copper; Dental Deposits; Dental Pellicle; Dental Plaque; DNA, Bacterial; Durapatite; Enzyme Inhibitors; Ferric Compounds; Ferrous Compounds; Glucans; Glucosyltransferases; Metals; Oxidants; Saliva; Sorbitol; Streptococcus mutans; Sucrose; Sweetening Agents; Xylitol; Zinc

1999
Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport.
    The Journal of biological chemistry, 2004, Jun-18, Volume: 279, Issue:25

    Topics: 1-Deoxynojirimycin; Androstenes; Animals; Antigens, CD; Biological Transport; Boron Compounds; Brain; Cell Line; Centrifugation, Density Gradient; CHO Cells; Cholesterol; Chromatography, High Pressure Liquid; Cricetinae; Detergents; Endosomes; Enzyme Inhibitors; Glucosyltransferases; Glycosphingolipids; Golgi Apparatus; Lactosylceramides; Mass Spectrometry; Membrane Microdomains; Mice; Mice, Transgenic; Models, Biological; Niemann-Pick Diseases; Octoxynol; Phenotype; Progesterone; Sucrose; Ultracentrifugation

2004
Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity.
    Acta crystallographica. Section D, Biological crystallography, 2013, Volume: 69, Issue:Pt 2

    Topics: 1-Deoxynojirimycin; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Disaccharides; Glucose; Glucosyltransferases; Hydrolysis; Isomaltose; Ligands; Mutation; Random Allocation; Rhizobium; Sucrose

2013
Inhibition of postprandial hyperglycemia by either an insulin-dependent or -independent drug reduces the expression of genes related to inflammation in peripheral leukocytes of OLETF rats.
    Bioscience, biotechnology, and biochemistry, 2013, Volume: 77, Issue:11

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Gene Expression; Hyperglycemia; Hypoglycemic Agents; Inflammation; Insulin; Interleukin-18; Interleukin-1beta; Leukocytes, Mononuclear; Male; Pyrimidines; Rats; Rats, Inbred OLETF; Receptors, Interleukin-1; S100 Proteins; Sucrose; TNF Receptor-Associated Factor 2

2013