1-deoxynojirimycin has been researched along with n-nonyl-1-deoxynojirimycin in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 10 (47.62) | 29.6817 |
| 2010's | 9 (42.86) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Adachi, I; Asano, N; Compain, P; Godin, G; Ikeda, K; Kato, A; Martin, O; Yu, L | 1 |
| Codd, R; Liao, V; Lifa, T; Liu, J; Obando, D | 1 |
| Benjamin, ER; Boyd, RE; Khanna, R; Lee, G; Rybczynski, P; Valenzano, KJ; Wustman, BA | 1 |
| Block, TM; Chang, J; Du, Y; Guo, F; Guo, J; Guo, JT; Kinney, W; Lam, P; Li, Y; Lu, H; Ma, J; Su, Q; Wu, S; Yan, Z; Yang, K; Zhang, X | 1 |
| Block, TM; Blumberg, BS; Dwek, RA; Ebling, M; Jacob, GS; Korba, B; Lansky, DM; Lu, X; Mehta, AS; Tennant, B | 1 |
| Block, TM; Butters, T; Carrouée, S; Conyers, B; Dwek, RA; Jordan, R; Mehta, A | 1 |
| Dwek, RA; Lee, CJ; Liao, CL; Lin, YL; Wu, SF; Zitzmann, N | 1 |
| Balch, WE; Beutler, E; Cheng, WC; Kelly, JW; Sawkar, AR; Wong, CH | 1 |
| Block, TM; Dwek, RA; Jacob, G; Jordan, R; Lu, X; Mehta, A; Moriarty, RM; Ouzounov, S; Simsek, E | 1 |
| Andersson, U; Butters, TD; Dwek, RA; Platt, FM; Reinkensmeier, G | 1 |
| Flamand, M; Liu, W; Schul, W; Vasudevan, SG; Xu, HY | 1 |
| Griffin, S; Harris, M; Owsianka, AM; Patel, AH; Rowlands, D; Stgelais, C | 1 |
| Block, TM; Bourne, N; Chang, J; Gu, B; Guo, H; Guo, JT; Ma, D; Mason, PM; Moriarty, R; Qu, X; Wang, L; Xu, X | 1 |
| Aguilar-Moncayo, M; García Fernández, JM; García-Moreno, MI; Higaki, K; Luan, Z; Ninomiya, H; Ohno, K; Ortiz Mellet, C; Suzuki, Y | 1 |
| Betesh, L; Block, TM; Cote, PJ; Mehta, AS; Menne, S; Norton, PA; Philip, R; Sinnathamby, G; Tennant, BC | 1 |
| Butters, TD; Twigg, G; Wang, GN; Ye, XS; Zhang, L; Zhang, LH; Zhang, S | 1 |
| Benedict, D; Buttner, J; Callahan, JW; Crushell, E; Mahuran, DJ; Martin, DR; Rigat, BA; Tropak, MB | 1 |
| McKeating, JA; Meredith, LW; Zitzmann, N | 1 |
| Gu, Y; Harvey, DJ; Hussain, S; McCauley, JW; Miller, JL; Rosenthal, PB; Zitzmann, N | 1 |
| Christy, JP; George Priya Doss, C; Iyer, S; Siva, R; Tayubi, IA; Thirumal Kumar, D; Zayed, H | 1 |
| Egawa, K; Fujii, H; Fukushi, S; Katano, H; Kimura, M; Kishi, H; Morikawa, S; Ozawa, T; Saijo, M; Sano, K; Shimojima, M; Suzuki, T; Tan, L; Tani, H; Taniguchi, S; Yamada, H | 1 |
3 review(s) available for 1-deoxynojirimycin and n-nonyl-1-deoxynojirimycin
| Article | Year |
|---|---|
The many faces of the adamantyl group in drug design.
Topics: Adamantane; Animals; Antimalarials; Diabetes Mellitus, Type 2; Drug Design; Humans; Hypoglycemic Agents; Iron Chelating Agents; Iron Overload; Malaria; Solubility | 2011 |
Pharmacological chaperones as therapeutics for lysosomal storage diseases.
Topics: Cell Line; Glycolipids; Humans; Lysosomal Storage Diseases; Molecular Chaperones; Structure-Activity Relationship | 2013 |
A comparative computational approach toward pharmacological chaperones (NN-DNJ and ambroxol) on N370S and L444P mutations causing Gaucher's disease.
Topics: 1-Deoxynojirimycin; Ambroxol; Gaucher Disease; Glucosylceramidase; Humans; Models, Molecular; Molecular Chaperones; Mutation | 2019 |
1 trial(s) available for 1-deoxynojirimycin and n-nonyl-1-deoxynojirimycin
| Article | Year |
|---|---|
Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Biological Transport; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Glucosides; Glycoside Hydrolase Inhibitors; Glycosylation; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Mannosides; Marmota; Oligosaccharides; Protein Folding; Rodent Diseases; Virus Replication | 1998 |
17 other study(ies) available for 1-deoxynojirimycin and n-nonyl-1-deoxynojirimycin
| Article | Year |
|---|---|
Alpha-1-C-octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease.
Topics: 1-Deoxynojirimycin; Cell Line; Dose-Response Relationship, Drug; Gaucher Disease; Glucosamine; Glucosylceramidase; Humans; Molecular Chaperones; Molecular Mimicry; Structure-Activity Relationship | 2006 |
Ester Prodrugs of IHVR-19029 with Enhanced Oral Exposure and Prevention of Gastrointestinal Glucosidase Interaction.
Topics: | 2017 |
Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Cattle; Cell Line; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Gene Products, pol; Glycoside Hydrolase Inhibitors; Hepatitis B virus; Intracellular Membranes; Polysaccharides | 2001 |
Antiviral effects of an iminosugar derivative on flavivirus infections.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Cell Line; Cricetinae; Dengue; Dengue Virus; Encephalitis Virus, Japanese; Encephalitis, Japanese; Female; Glycoside Hydrolase Inhibitors; Mice; Mice, Inbred ICR | 2002 |
Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease.
Topics: 1-Deoxynojirimycin; Alkylation; Amino Acid Substitution; beta-Glucosidase; Cells, Cultured; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Fibroblasts; Gaucher Disease; Golgi Apparatus; Heterocyclic Compounds; Humans; Hydrogen-Ion Concentration; Lysosomes; Molecular Structure; Morpholines; Protein Denaturation; Protein Folding; Protein Transport; Structure-Activity Relationship | 2002 |
Imino sugars that are less toxic but more potent as antivirals, in vitro, compared with N-n-nonyl DNJ.
Topics: 1-Deoxynojirimycin; Alkylation; Animals; Antiviral Agents; Carbohydrates; Cell Line; Cyclization; Diarrhea Viruses, Bovine Viral; Glucosamine; Hepatitis B virus; Humans; Molecular Structure | 2002 |
Inhibition of glycogen breakdown by imino sugars in vitro and in vivo.
Topics: 1-Deoxynojirimycin; Animals; Female; Glycogen; Glycoside Hydrolase Inhibitors; Mice; Mice, Inbred C57BL | 2004 |
A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Dengue; Disease Models, Animal; Dose-Response Relationship, Drug; Indolizines; Mice; Ribavirin; Time Factors; Tubercidin; Viremia; Virus Replication | 2007 |
Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel.
Topics: 1-Deoxynojirimycin; Amantadine; Amino Acid Sequence; Antiviral Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Genotype; Hepacivirus; Hepatitis C; Humans; Liver Neoplasms; Molecular Sequence Data; Rimantadine; Viral Proteins; Virus Replication | 2008 |
Novel imino sugar derivatives demonstrate potent antiviral activity against flaviviruses.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Cattle; Cell Line; Cricetinae; Flavivirus; Glycoside Hydrolase Inhibitors; Imino Sugars; Structure-Activity Relationship | 2009 |
Chaperone activity of bicyclic nojirimycin analogues for Gaucher mutations in comparison with N-(n-nonyl)deoxynojirimycin.
Topics: 1-Deoxynojirimycin; Animals; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Gaucher Disease; Glucosylceramidase; Humans; Imino Sugars; Molecular Chaperones; Molecular Structure; Mutation; Protein Conformation; Protein Folding | 2009 |
Glucosidase inhibition enhances presentation of de-N-glycosylated hepatitis B virus epitopes by major histocompatibility complex class I in vitro and in woodchucks.
Topics: 1-Deoxynojirimycin; Animals; Enzyme Inhibitors; Epitopes; Genes, MHC Class I; Glucosidases; Hepatitis B virus; Hepatitis B Virus, Woodchuck; Humans; Indolizines; Leukocytes, Mononuclear; Marmota; Viral Envelope Proteins | 2010 |
Synthesis of N-substituted ε-hexonolactams as pharmacological chaperones for the treatment of N370S mutant Gaucher disease.
Topics: 1-Deoxynojirimycin; Cell Survival; Cells, Cultured; Enzyme Activation; Enzyme Activators; Gaucher Disease; Glucosylceramidase; Humans; Imino Sugars; Kinetics; Lactams; Models, Molecular; Mutation; Protein Folding; Structure-Activity Relationship | 2012 |
Evaluation of N-nonyl-deoxygalactonojirimycin as a pharmacological chaperone for human GM1 gangliosidosis leads to identification of a feline model suitable for testing enzyme enhancement therapy.
Topics: 1-Deoxynojirimycin; Animals; beta-Galactosidase; Cats; Cell Line, Tumor; Disease Models, Animal; Enzyme Replacement Therapy; Fibroblasts; Gangliosidosis, GM1; Hot Temperature; Humans; Hydrogen-Ion Concentration; Mutant Proteins; Mutation; Protein Denaturation; Treatment Outcome | 2012 |
Differential effect of p7 inhibitors on hepatitis C virus cell-to-cell transmission.
Topics: 1-Deoxynojirimycin; Antiviral Agents; Cell Communication; Cell Line; Coculture Techniques; Genotype; Guanidines; Hepacivirus; Humans; Pyrazoles; Reassortant Viruses; Rimantadine; Viral Proteins; Virus Assembly; Virus Attachment; Virus Cultivation | 2013 |
Strain-specific antiviral activity of iminosugars against human influenza A viruses.
Topics: 1-Deoxynojirimycin; Antiviral Agents; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Microbial Sensitivity Tests; Virus Replication | 2015 |
Characterization of pseudotyped vesicular stomatitis virus bearing the heartland virus envelope glycoprotein.
Topics: 1-Deoxynojirimycin; Animals; Bunyaviridae Infections; Cell Line; Cricetinae; Haplorhini; Humans; Mice; Phlebovirus; Vesicular Stomatitis; Vesiculovirus; Viral Envelope Proteins; Virus Internalization | 2021 |