Page last updated: 2024-08-23

1-deoxynojirimycin and mannose

1-deoxynojirimycin has been researched along with mannose in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199023 (41.07)18.7374
1990's22 (39.29)18.2507
2000's8 (14.29)29.6817
2010's3 (5.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergmann, JE; Gabel, CA; Suh, K1
Bischoff, J; Folkman, J; Nguyen, M1
el Battari, A; Forget, P; Fouchier, F; Pic, P1
Smith, ME1
Kimura, Y; Suehisa, H; Takagi, S; Yamaguchi, O1
Doskoch, PM; Houghton, AN; Vijayasaradhi, S1
Aubery, M; Codogno, P; Ogier-Denis, E; Sapin, C; Trugnan, G1
Elbein, AD; Kaushal, GP; Mitchell, M; Tropea, JE1
Decker, K; Gerok, W; Gross, V; Häussinger, D; Heinrich, PC; Steube, K; Tran-Thi, TA1
Broxterman, HJ; Lindhout, J; Neefjes, JJ; Ploegh, HL; van Boom, JH; van der Marel, GA1
Hoke, GM; Pal, R; Sarngadharan, MG1
Bouchilloux, S; Fayet, G; Franc, JL; Hovsepian, S1
Bause, E; Legler, G; Schweden, J1
Burns, G; Conary, J; Hasilik, A; Nauerth, A; von Figura, K1
Herscovics, A; Romero, PA2
Jamieson, JC; Spearman, MA; Wright, JA1
Elbein, AD; Hori, H; Pan, YT1
Cacan, R; Cecchelli, R; Verbert, A1
Arakaki, RF; Collier, E; Gorden, P; Hedo, JA1
Datema, R; McDowell, W; Romero, PA; Schwarz, RT1
Bause, E; Foddy, L; Hughes, RC1
Touster, O; Tulsiani, DR1
Gillette, RW; Long, CG; McKearn, TJ; Rodwell, JD; Simonson, RB; Ultee, ME1
Hirani, S; Kong, N; Lodish, HF; Rasmussen, J1
Friedlander, P; Herscovics, A; Romero, PA1
Decker, K; Gerok, W; Gross, V; Heinrich, PC; McDowell, W; Schwarz, RT; Steube, K; Tran-Thi, TA1
Elbein, AD1
Mersmann, G; Ziegler, C1
Jülich, E; Legler, G1
Elbein, AD; Legler, G; McDowell, W; Schwarz, R; Tlusty, A1
Herrler, G; Maisner, A1
Achiwa, K; Suhara, Y1
Touster, O; Wilkerson, LS1
Elbein, AD; Kaushal, GP1
Abouakil, N; Benajiba, A; Bruneau, N; Lombardo, D; Mas, E1
Blais, A; Codogno, P; Houri, JJ; Ogier-Denis, E; Trugnan, G; Voisin, T1
Geilen, CC; Heidrich, C; Nuck, R; Paul, C; Reutter, W; Wieland, B1
Brostrom, CO; Brostrom, MA; Kuznetsov, G1
Butters, TD; Dwek, RA; Karlsson, GB; Platt, FM1
Coutinho, PM; Dowd, MK; Reilly, PJ1
Furumai, T; Igarashi, Y; Oki, T; Yamazaki, Y1
Eneyskaya, EV; Golubev, AM; Kulminskaya, AA; Neustroev, KN; Savel'ev, AN; Shabalin, KA1
Ding, Y; Hindsgaul, O1
Furumai, T; Igarashi, Y; Nomura, N; Oki, T; Yamazaki, Y1
Chung, DH; Hirosawa, S; Miyasaka, N; Ohashi, K; Watanabe, M1
Cacan, R; Chirat, F; Dubuisson, J; Duvet, S; Mir, AM; Verbert, A1
Murphy, PV; O'Brien, JL; Tosin, M1
Hara, K; Koide, T; Tokunaga, F1
Kuntz, DA; Rose, DR; Shah, N1
Butters, TD; Dwek, RA; Harvey, DJ; Mellor, HR; Neville, DC; Platt, FM1
Fujikawa, H; Kanno, T; Nagai, K; Nagata, T; Nishizaki, T; Tashiro, C; Watanabe, K; Yaguchi, T; Yamamoto, H; Yamamoto, S; Yang, D1
Miyake, K; Nagai, K1
Adachi, I; Akimitsu, K; Fleet, GW; Izumori, K; Jenkinson, SF; Kato, A; Lenagh-Snow, GM; Morimoto, K; Nakagawa, S; Newberry, SJ; Wormald, MR; Yoshihara, A1
Besenbacher, LM; Jensen, HH; Jensen, MT; Kamori, A; Kato, A; Kilian, M; Viuff, AH1
Abraham, G; Aharonovitz, O; Aloni, Y; Kenett, D; Maor-Shoshani, A; Shalel Levanon, S1

Reviews

1 review(s) available for 1-deoxynojirimycin and mannose

ArticleYear
Inhibitors of the biosynthesis and processing of N-linked oligosaccharides.
    CRC critical reviews in biochemistry, 1984, Volume: 16, Issue:1

    Topics: 1-Deoxynojirimycin; Acetylglucosamine; Alkaloids; Animals; Anti-Bacterial Agents; Asparagine; Bacitracin; Biological Transport; Carbohydrate Conformation; Cyclohexenes; Dolichol Phosphates; Glucosamine; Glucose; Glycoproteins; Hydroxycholesterols; Indolizines; Inositol; Lipopeptides; Lovastatin; Mannose; Naphthalenes; Oligopeptides; Oligosaccharides; Peptides; Peptides, Cyclic; Phospholipids; Polyisoprenyl Phosphate Monosaccharides; Pyrimidine Nucleosides; Showdomycin; Structure-Activity Relationship; Swainsonine; Tunicamycin; Uracil

1984

Other Studies

55 other study(ies) available for 1-deoxynojirimycin and mannose

ArticleYear
Identification of a novel mechanism for the removal of glucose residues from high mannose-type oligosaccharides.
    The Journal of biological chemistry, 1992, Oct-25, Volume: 267, Issue:30

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Cell Compartmentation; Electrophoresis, Gel, Pulsed-Field; Glucose; Glycoproteins; Glycosylation; Kinetics; Mannose; Membrane Glycoproteins; Mice; Oligosaccharides; Tumor Cells, Cultured; Vesicular stomatitis Indiana virus; Viral Envelope Proteins

1992
1-Deoxymannojirimycin inhibits capillary tube formation in vitro. Analysis of N-linked oligosaccharides in bovine capillary endothelial cells.
    The Journal of biological chemistry, 1992, Dec-25, Volume: 267, Issue:36

    Topics: 1-Deoxynojirimycin; Adrenal Cortex; Alkaloids; Animals; Capillaries; Carbohydrate Conformation; Carbohydrate Sequence; Cattle; Cells, Cultured; Chromatography, Affinity; Chromatography, Gel; Clone Cells; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Glycopeptides; Mannose; Mannosidases; Molecular Sequence Data; Oligosaccharides; Swainsonine

1992
Effect of inhibiting N-glycosylation or oligosaccharide processing on vasoactive intestinal peptide receptor binding activity and structure.
    The Biochemical journal, 1991, Sep-01, Volume: 278 ( Pt 2)

    Topics: 1-Deoxynojirimycin; Alkaloids; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Glucosamine; Glycosylation; Humans; Indolizines; Mannose; Methionine; Molecular Weight; Oligosaccharides; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Structure-Activity Relationship; Swainsonine; Tumor Cells, Cultured; Tunicamycin; Vasoactive Intestinal Peptide

1991
Effects of inhibitors of oligosaccharide processing on P0 protein synthesis and incorporation into PNS myelin.
    Journal of neurochemistry, 1991, Volume: 57, Issue:2

    Topics: 1-Deoxynojirimycin; Alkaloids; Amino Acids; Animals; Carbohydrate Sequence; Carbon Radioisotopes; Fucose; Glucosamine; Glycoproteins; Glycoside Hydrolases; Indolizines; Mannose; Molecular Sequence Data; Molecular Weight; Myelin P0 Protein; Myelin Proteins; Myelin Sheath; Oligosaccharides; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; Sciatic Nerve; Swainsonine; Tritium

1991
In vitro hydrolysis of oligomannose-type sugar chains by an alpha-1,2-mannosidase from microsomes of developing castor bean cotyledons.
    Biochimica et biophysica acta, 1991, Sep-02, Volume: 1075, Issue:1

    Topics: 1-Deoxynojirimycin; Carbohydrate Sequence; Chromatography, Gel; Edetic Acid; Glucosamine; Hydrolysis; Mannose; Mannosidases; Microsomes; Molecular Sequence Data; Plant Development; Plants

1991
Biosynthesis and intracellular movement of the melanosomal membrane glycoprotein gp75, the human b (brown) locus product.
    Experimental cell research, 1991, Volume: 196, Issue:2

    Topics: 1-Deoxynojirimycin; Alkaloids; Antibodies, Monoclonal; Cell Line; Fucose; Glucosamine; Glycoside Hydrolases; Glycosylation; Humans; Indolizines; Mannose; Melanoma; Membrane Glycoproteins; Methionine; Molecular Weight; Protein Processing, Post-Translational; Swainsonine; Tunicamycin

1991
Dual effect of 1-deoxymannojirimycin on the mannose uptake and on the N-glycan processing of the human colon cancer cell line HT-29.
    The Journal of biological chemistry, 1990, Apr-05, Volume: 265, Issue:10

    Topics: 1-Deoxynojirimycin; Adenocarcinoma; alpha-Mannosidase; Cell Differentiation; Colonic Neoplasms; Glucosamine; Humans; Kinetics; Mannose; Mannosidases; Polysaccharides; Tumor Cells, Cultured

1990
Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I.
    The Journal of biological chemistry, 1990, Sep-15, Volume: 265, Issue:26

    Topics: 1-Deoxynojirimycin; Actinomycetales; Alkaloids; Animals; Cell Line; Cytosol; Glucosamine; Golgi Apparatus; Kinetics; Liver; Male; Mannose; Mannosidases; Microsomes, Liver; Oligosaccharides; Plants; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains

1990
Clearance of acute-phase plasma proteins with no, high-mannose-, hybrid-, or complex type oligosaccharide side chains by the isolated perfused rat liver.
    Biochemical and biophysical research communications, 1986, Dec-30, Volume: 141, Issue:3

    Topics: 1-Deoxynojirimycin; Alkaloids; alpha 1-Antitrypsin; alpha-Macroglobulins; Animals; Blood Proteins; Cells, Cultured; Glucosamine; Glycosylation; Kinetics; Liver; Mannose; Oligosaccharides; Orosomucoid; Rats; Swainsonine

1986
Non-carrier-mediated uptake of the mannosidase I inhibitor 1-deoxymannojirimycin by K562 erythroleukemic cells.
    The Journal of biological chemistry, 1989, Jun-15, Volume: 264, Issue:17

    Topics: 1-Deoxynojirimycin; Biological Transport; Cell Line; Glucosamine; Glucose; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mannose; Mannosidases; Tritium

1989
Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:9

    Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Glucosidases; Cell Line; Endoplasmic Reticulum; Glucosamine; Glycoproteins; Glycoside Hydrolase Inhibitors; Glycosylation; Golgi Apparatus; HIV Antigens; HIV Envelope Protein gp120; HIV Envelope Protein gp160; HIV Envelope Protein gp41; HIV-1; Mannose; Mannosidases; Oligosaccharides; Retroviridae Proteins; Swainsonine; Tunicamycin; Viral Envelope Proteins

1989
Inhibition of N-linked oligosaccharide processing does not prevent the secretion of thyroglobulin. A study with swainsonine and deoxynojirimycin.
    European journal of biochemistry, 1986, May-15, Volume: 157, Issue:1

    Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Mannosidase; Animals; Glucosamine; Glycoside Hydrolases; Hexosaminidases; Leucine; Mannose; Mannosidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Oligosaccharides; Pronase; Swainsonine; Swine; Thyroglobulin; Thyroid Gland

1986
Purification and characterization of a neutral processing mannosidase from calf liver acting on (Man)9(GlcNAc)2 oligosaccharides.
    European journal of biochemistry, 1986, Jun-16, Volume: 157, Issue:3

    Topics: 1-Deoxynojirimycin; Acetylglucosamine; Animals; Cations, Divalent; Cattle; Chromatography; Glucosamine; Hydrogen-Ion Concentration; Kinetics; Mannose; Mannosidases; Microsomes, Liver; Oligosaccharides; Solubility; Substrate Specificity

1986
Steroid sulfatase. Biosynthesis and processing in normal and mutant fibroblasts.
    European journal of biochemistry, 1986, Jul-01, Volume: 158, Issue:1

    Topics: 1-Deoxynojirimycin; Cells, Cultured; Endoplasmic Reticulum; Fibroblasts; Glucosamine; Golgi Apparatus; Humans; Ichthyosis; Lysosomes; Mannose; Molecular Weight; Mutation; Oligosaccharides; Steryl-Sulfatase; Sulfatases

1986
Effects of tunicamycin, N-methyl-1-deoxynojirimycin, and manno-1-deoxynojirimycin on the biosynthesis of lactosaminoglycans in F9 teratocarcinoma cells.
    Carbohydrate research, 1986, Aug-15, Volume: 151

    Topics: 1-Deoxynojirimycin; Amino Sugars; Anti-Bacterial Agents; Cell Line; Galactose; Glucosamine; Glycopeptides; Mannose; Oligosaccharides; Polysaccharides; Teratoma; Tritium; Tunicamycin

1986
Studies on the effect of glycoprotein processing inhibitors on fusion of L6 myoblast cell lines.
    Experimental cell research, 1987, Volume: 168, Issue:1

    Topics: 1-Deoxynojirimycin; Alkaloids; Cell Fusion; Cell Line; Concanavalin A; Glucosamine; Glycoproteins; Indolizines; Mannose; Muscles; Oligosaccharides; Swainsonine; Wheat Germ Agglutinins

1987
The effect of glycoprotein-processing inhibitors on the secretion of glycoproteins by Madin-Darby canine kidney cells.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1987, Volume: 65, Issue:4

    Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Cell Line; Dogs; Glucosamine; Glycopeptides; Glycoproteins; Glycoside Hydrolases; Indolizines; Kidney; Kinetics; Mannose; Swainsonine

1987
Catabolic pathway of oligosaccharide-diphospho-dolichol. Study of the fate of the oligosaccharidic moiety in mouse splenocytes.
    European journal of biochemistry, 1987, Jul-15, Volume: 166, Issue:2

    Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Glucosamine; Glucosidases; Indolizines; Kinetics; Mannose; Mice; Oligosaccharides; Polyisoprenyl Phosphate Oligosaccharides; Polyisoprenyl Phosphate Sugars; Spleen; Tritium; Tunicamycin

1987
Effects of castanospermine and 1-deoxynojirimycin on insulin receptor biogenesis. Evidence for a role of glucose removal from core oligosaccharides.
    The Journal of biological chemistry, 1987, Aug-25, Volume: 262, Issue:24

    Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; Alkaloids; Cell Line; Chromatography, High Pressure Liquid; Glucosamine; Glucose; Glucosidases; Humans; Indolizines; Insulin; Leucine; Mannose; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Oligosaccharides; Receptor, Insulin

1987
Glucose trimming and mannose trimming affect different phases of the maturation of Sindbis virus in infected BHK cells.
    Virology, 1987, Volume: 161, Issue:1

    Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Cell Line; Culture Media; Glucosamine; Glucose; Glucosidases; Glycoproteins; Glycosylation; Mannose; Mannosidases; Microscopy, Electron; Protein Processing, Post-Translational; Sindbis Virus; Viral Proteins

1987
Asparagine-linked oligosaccharides of BHK cells treated with inhibitors of oligosaccharide processing.
    The Biochemical journal, 1987, Nov-01, Volume: 247, Issue:3

    Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Asparagine; Cell Line; Chromatography, Affinity; Chromatography, Gel; Cricetinae; Glucosamine; Glucose; Glycopeptides; Glycosylation; Lectins; Mannose; Mannosidases; Oligosaccharides

1987
The purification and characterization of mannosidase IA from rat liver Golgi membranes.
    The Journal of biological chemistry, 1988, Apr-15, Volume: 263, Issue:11

    Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Glucosamine; Golgi Apparatus; Hexosaminidases; Isoenzymes; Liver; Male; Mannose; Mannosidases; Molecular Weight; Octoxynol; Polyethylene Glycols; Rats; Rats, Inbred Strains

1988
Inhibition of mannosidase in hybridomas yields monoclonal antibodies with greater capacity for carbohydrate labeling.
    Clinical chemistry, 1988, Volume: 34, Issue:9

    Topics: 1-Deoxynojirimycin; Acetylglucosamine; Acetylglucosaminidase; Animals; Antibodies, Monoclonal; Antigens; Carbohydrates; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Glucosamine; Humans; Hybridomas; Indium Radioisotopes; Mannose; Mannosidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Neoplasms, Experimental; Tumor Cells, Cultured

1988
A vesicular intermediate in the transport of hepatoma secretory proteins from the rough endoplasmic reticulum to the Golgi complex.
    The Journal of cell biology, 1987, Volume: 104, Issue:2

    Topics: 1-Deoxynojirimycin; alpha 1-Antitrypsin; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cytoplasmic Granules; Endoplasmic Reticulum; Glucosamine; Golgi Apparatus; Humans; Kinetics; Liver Neoplasms; Mannose; Neoplasm Proteins

1987
Deoxynojirimycin inhibits the formation of Glc3Man9GlcNAc2-PP-dolichol in intestinal epithelial cells in culture.
    FEBS letters, 1985, Apr-08, Volume: 183, Issue:1

    Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Cell Line; Epithelium; Glucosamine; Intestinal Mucosa; Intestines; Mannose; Mannosidases; Oligosaccharides; Polyisoprenyl Phosphate Sugars; Rats

1985
Secretion of high-mannose-type alpha 1-proteinase inhibitor and alpha 1-acid glycoprotein by primary cultures of rat hepatocytes in the presence of the mannosidase I inhibitor 1-deoxymannojirimycin.
    European journal of biochemistry, 1985, Jul-01, Volume: 150, Issue:1

    Topics: 1-Deoxynojirimycin; Acrylic Resins; alpha 1-Antitrypsin; Animals; Blood Proteins; Cells, Cultured; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Glucosamine; Hexosaminidases; Immunochemistry; Liver; Mannose; Mannosidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Oligosaccharides; Orosomucoid; Rats

1985
Transfer of nonglucosylated oligosaccharide from lipid to protein in a mammalian cell.
    The Journal of biological chemistry, 1986, Dec-05, Volume: 261, Issue:34

    Topics: 1-Deoxynojirimycin; Cells, Cultured; Chromatography, Affinity; Chromatography, High Pressure Liquid; Dolichol Phosphates; Glucosamine; Lipid Metabolism; Mannose; Oligosaccharides; Proteins

1986
Influence of effectors of the complex-type-oligosaccharide biosynthesis on the formation of proteokeratan sulfate in bovine cornea.
    Biochimica et biophysica acta, 1984, Jun-29, Volume: 799, Issue:3

    Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Mannosidase; Animals; Cattle; Chondroitin Sulfate Proteoglycans; Cornea; Culture Techniques; Deoxyglucose; Glucosamine; Glycosaminoglycans; Keratan Sulfate; Lumican; Mannose; Mannosidases; Proteoglycans; Swainsonine; Swine; Tunicamycin

1984
Synthesis of 5-amino-5-deoxy-D-mannopyranose and 1,5-dideoxy-1,5-imino-D-mannitol, and inhibition of alpha- and beta-D-mannosidases.
    Carbohydrate research, 1984, May-15, Volume: 128, Issue:1

    Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Aspergillus; beta-Mannosidase; Binding Sites; Cattle; Hexosamines; Indicators and Reagents; Kinetics; Liver; Mannitol; Mannose; Mannosidases; Optical Rotation; Plants

1984
The effect of deoxymannojirimycin on the processing of the influenza viral glycoproteins.
    Archives of biochemistry and biophysics, 1984, Volume: 235, Issue:2

    Topics: 1-Deoxynojirimycin; Alkaloids; Antiviral Agents; Chemical Phenomena; Chemistry; Glucosamine; Glycoproteins; Indolizines; Leucine; Lipids; Mannose; Oligosaccharides; Orthomyxoviridae; Protein Processing, Post-Translational; Viral Proteins

1984
Membrane cofactor protein with different types of N-glycans can serve as measles virus receptor.
    Virology, 1995, Jul-10, Volume: 210, Issue:2

    Topics: 1-Deoxynojirimycin; Animals; Antigens, CD; Chlorocebus aethiops; Glycosylation; Mannose; Measles virus; Membrane Cofactor Protein; Membrane Glycoproteins; Molecular Weight; Oligosaccharides; Polysaccharides; Receptors, Virus; Tunicamycin; Vero Cells

1995
Disaccharides as endomannosidase inhibitors: syntheses of alpha-homomannojirimycin and beta-homomannojirimycin linked to D-glucose and D-mannose.
    Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:3

    Topics: 1-Deoxynojirimycin; Antiviral Agents; Carbohydrate Sequence; Disaccharides; Glucose; Imino Pyranoses; Mannose; Mannosidases; Molecular Sequence Data; Piperidines

1995
Biosynthetic and structural studies on Thy-1 in a rat neuronal tumor cell line.
    Archives of biochemistry and biophysics, 1993, Volume: 303, Issue:2

    Topics: 1-Deoxynojirimycin; Animals; Antigens, Surface; Biological Transport; Brefeldin A; Chromatography, High Pressure Liquid; Cyclopentanes; Fucose; Glycosylation; Indolizines; Mannose; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Membrane Glycoproteins; Neurons; Rats; Swainsonine; Thy-1 Antigens; Tumor Cells, Cultured; Tunicamycin

1993
Glycosidase inhibitors in study of glycoconjugates.
    Methods in enzymology, 1994, Volume: 230

    Topics: 1-Deoxynojirimycin; Animals; Carbohydrate Sequence; Cell Line; Cells, Cultured; Dogs; Galactose; Glucosidases; Glycoconjugates; Glycoproteins; Glycoside Hydrolases; Indolizines; Isotope Labeling; Kidney; Mannose; Mannosidases; Molecular Sequence Data; Oligosaccharides; Swainsonine

1994
Bile salt-dependent lipase biosynthesis in rat pancreatic AR 4-2 J cells. Essential requirement of N-linked oligosaccharide for secretion and expression of a fully active enzyme.
    The Journal of biological chemistry, 1993, Dec-05, Volume: 268, Issue:34

    Topics: 1-Deoxynojirimycin; Amino Acids; Animals; Autoradiography; Carbohydrate Metabolism; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Gene Expression; Glucosidases; Glycosylation; Indolizines; Kinetics; Lipase; Mannose; Methionine; Molecular Weight; Pancreas; Pancreatic Neoplasms; Rats; Sterol Esterase; Sulfur Radioisotopes; Swainsonine; Thermodynamics; Tritium; Tumor Cells, Cultured; Tunicamycin

1993
The emergence of a basolateral 1-deoxymannojirimycin-sensitive mannose carrier is a function of intestinal epithelial cell differentiation. Evidence for a new inhibitory effect of 1-deoxymannojirimycin on facilitative mannose transport.
    The Journal of biological chemistry, 1994, Feb-11, Volume: 269, Issue:6

    Topics: 1-Deoxynojirimycin; Animals; Biological Transport; Carrier Proteins; Cell Differentiation; Cell Line; Cell Polarity; Humans; In Vitro Techniques; Intestinal Mucosa; Male; Mannose; Monosaccharide Transport Proteins; Rats; Rats, Wistar

1994
Comparative study of high-mannose-type oligosaccharides in membrane glycoproteins of rat hepatocytes and different rat hepatoma cell lines.
    European journal of biochemistry, 1993, Aug-15, Volume: 216, Issue:1

    Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; Animals; Carbohydrate Sequence; Cells, Cultured; Chromatography, High Pressure Liquid; Hexosaminidases; Liver; Liver Neoplasms, Experimental; Mannose; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Membrane Glycoproteins; Molecular Sequence Data; Oligosaccharides; Rats; Rats, Wistar; Tumor Cells, Cultured

1993
Role of endoplasmic reticular calcium in oligosaccharide processing of alpha 1-antitrypsin.
    The Journal of biological chemistry, 1993, Jan-25, Volume: 268, Issue:3

    Topics: 1-Deoxynojirimycin; alpha 1-Antitrypsin; alpha-Mannosidase; Brefeldin A; Calcium; Calcium-Transporting ATPases; Carbohydrate Conformation; Carcinoma, Hepatocellular; Cyclopentanes; Endoplasmic Reticulum; Glycoside Hydrolase Inhibitors; Hexosaminidases; Humans; Indolizines; Ionomycin; Liver Neoplasms; Mannose; Mannosidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Oligosaccharides; Terpenes; Thapsigargin; Tumor Cells, Cultured

1993
Effects of the imino sugar N-butyldeoxynojirimycin on the N-glycosylation of recombinant gp120.
    The Journal of biological chemistry, 1993, Jan-05, Volume: 268, Issue:1

    Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Carbon Radioisotopes; CHO Cells; Chromatography, Gel; Cricetinae; Glycosylation; Hexosaminidases; HIV Envelope Protein gp120; HIV-1; Mannose; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Methionine; Oligosaccharides; Recombinant Proteins; Sulfur Radioisotopes; Transfection; Tritium

1993
Automated docking of monosaccharide substrates and analogues and methyl alpha-acarviosinide in the glucoamylase active site.
    Proteins, 1997, Volume: 27, Issue:2

    Topics: 1-Deoxynojirimycin; Aspergillus; Automation; Binding Sites; Catalysis; Computer Simulation; Disaccharides; Fungal Proteins; Galactose; Glucan 1,4-alpha-Glucosidase; Gluconates; Glucose; Lactones; Mannose; Models, Molecular; Monosaccharides; Substrate Specificity

1997
Pradimicin, a mannose-binding antibiotic, induced carbohydrate-mediated apoptosis in U937 cells.
    Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:8

    Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antigens, Surface; Apoptosis; Carbohydrates; Cell Line; DNA, Neoplasm; Electrophoresis, Agar Gel; Humans; Leukemia, Myeloid; Mannose; Oligosaccharides

1997
alpha-Mannosidase from Trichoderma reesei participates in the postsecretory deglycosylation of glycoproteins.
    Biochemical and biophysical research communications, 1998, Apr-07, Volume: 245, Issue:1

    Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Enzyme Inhibitors; Fungal Proteins; Glycoproteins; Glycosylation; Kinetics; Mannans; Mannose; Mannosidases; Substrate Specificity; Trichoderma

1998
Syntheses of 1-deoxy-3-s-(1-thio-alpha-D-glucopyranosyl)-mannojirimycin and 1-deoxy-3-O-(5-thio-alpha-D-glucopyranosyl)-mannojirimycin as potential inhibitors of endo-alpha-D-mannosidase.
    Bioorganic & medicinal chemistry letters, 1998, May-19, Volume: 8, Issue:10

    Topics: 1-Deoxynojirimycin; Drug Design; Enzyme Inhibitors; Glucosides; Glycosides; Indicators and Reagents; Mannose; Mannosidases; Molecular Structure; Piperidines; Structure-Activity Relationship

1998
High-mannose type oligosaccharide-dependent apoptosis in U937 cells induced by pradimicin, a mannose-binding antibiotic.
    The Journal of antibiotics, 1999, Volume: 52, Issue:5

    Topics: 1-Deoxynojirimycin; Anthracyclines; Antibiotics, Antineoplastic; Antifungal Agents; Apoptosis; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Glucosidases; Humans; Indolizines; Mannose; Mannosidases; Oligosaccharides; Swainsonine; U937 Cells

1999
Mannose trimming targets mutant alpha(2)-plasmin inhibitor for degradation by the proteasome.
    The Journal of biological chemistry, 2000, Feb-18, Volume: 275, Issue:7

    Topics: 1-Deoxynojirimycin; alpha-2-Antiplasmin; Animals; Calcium-Binding Proteins; Calnexin; CHO Cells; Cricetinae; Cysteine Endopeptidases; Golgi Apparatus; Hydrolysis; Indolizines; Mannose; Multienzyme Complexes; Mutation; Proteasome Endopeptidase Complex; Ubiquitins

2000
Reciprocal relationship between alpha1,2 mannosidase processing and reglucosylation in the rough endoplasmic reticulum of Man-P-Dol deficient cells.
    European journal of biochemistry, 2000, Volume: 267, Issue:4

    Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Brefeldin A; CHO Cells; Cricetinae; Dolichol Monophosphate Mannose; Endoplasmic Reticulum, Rough; Glycoproteins; Glycosylation; Mannose; Mannosidases; Mutation; Oligosaccharides; Protein Folding; Recombinant Proteins; Viral Proteins

2000
Novel synthesis of the glycosidase inhibitor deoxymannojirimycin and of a synthetic precursor D-lyxo-hexos-5-ulose.
    Organic letters, 2001, Oct-18, Volume: 3, Issue:21

    Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Antiviral Agents; Chemistry, Pharmaceutical; Enzyme Inhibitors; Epoxy Compounds; Glycoside Hydrolases; Mannose; Methylmannosides

2001
N-linked oligosaccharide processing, but not association with calnexin/calreticulin is highly correlated with endoplasmic reticulum-associated degradation of antithrombin Glu313-deleted mutant.
    Archives of biochemistry and biophysics, 2003, Mar-15, Volume: 411, Issue:2

    Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Antithrombins; Calnexin; Calreticulin; Carbohydrate Conformation; Cells, Cultured; Cricetinae; Cycloheximide; Endoplasmic Reticulum; Enzyme Inhibitors; Glucosidases; Indolizines; Mannose; Mannosidases; Mutation; Oligosaccharides; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Puromycin

2003
Comparison of kifunensine and 1-deoxymannojirimycin binding to class I and II alpha-mannosidases demonstrates different saccharide distortions in inverting and retaining catalytic mechanisms.
    Biochemistry, 2003, Dec-02, Volume: 42, Issue:47

    Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Mannosidase; Animals; Binding Sites; Carbohydrate Conformation; Catalysis; Crystallization; Crystallography, X-Ray; Drosophila melanogaster; Endoplasmic Reticulum; Energy Metabolism; Enzyme Inhibitors; Golgi Apparatus; Humans; Macromolecular Substances; Mannose; Mannosidases

2003
Cellular effects of deoxynojirimycin analogues: inhibition of N-linked oligosaccharide processing and generation of free glucosylated oligosaccharides.
    The Biochemical journal, 2004, Aug-01, Volume: 381, Issue:Pt 3

    Topics: 1-Deoxynojirimycin; Acetylglucosamine; alpha-Glucosidases; alpha-Mannosidase; Amino Sugars; Carbohydrate Conformation; Carbohydrate Sequence; Cell Line, Tumor; Chromatography, High Pressure Liquid; Glucose; Glycosylation; HL-60 Cells; Humans; Mannose; Oligosaccharides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2004
Beneficial effect of intracellular free high-mannose oligosaccharides on cryopreservation of mammalian cells and proteins.
    Cryobiology, 2006, Volume: 53, Issue:3

    Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Cell Survival; Cryopreservation; Cryoprotective Agents; Enzyme Inhibitors; Intracellular Fluid; Mannans; Mannose; Oligosaccharides; PC12 Cells; Protein Kinase C-epsilon; Rats

2006
Inhibition of alpha-mannosidase attenuates endoplasmic reticulum stress-induced neuronal cell death.
    Neurotoxicology, 2009, Volume: 30, Issue:1

    Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Amyloid; Animals; Cell Death; Cell Line, Transformed; Cells, Cultured; Cricetinae; Endoplasmic Reticulum; Enzyme Inhibitors; Mannose; Mice; Neurons; Rats; Stress, Physiological

2009
Eight stereoisomers of homonojirimycin from D-mannose.
    Organic letters, 2012, Apr-20, Volume: 14, Issue:8

    Topics: 1-Deoxynojirimycin; Euphorbiaceae; Mannose; Molecular Structure; Stereoisomerism

2012
Stable analogues of nojirimycin--synthesis and biological evaluation of nojiristegine and manno-nojiristegine.
    Organic & biomolecular chemistry, 2015, Oct-07, Volume: 13, Issue:37

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Anti-Bacterial Agents; Bacteria; Chemistry Techniques, Synthetic; Drug Stability; Glycoside Hydrolase Inhibitors; Humans; Inhibitory Concentration 50; Mannose

2015
An efficient method to control high mannose and core fucose levels in glycosylated antibody production using deoxymannojirimycin.
    Journal of biotechnology, 2018, Jun-20, Volume: 276-277

    Topics: 1-Deoxynojirimycin; Animals; Bioreactors; CHO Cells; Cricetinae; Cricetulus; Fucose; Glycosylation; Immunoglobulin G; Mannose; Recombinant Proteins

2018