Page last updated: 2024-08-23

1-deoxynojirimycin and glycogen

1-deoxynojirimycin has been researched along with glycogen in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.76)18.7374
1990's6 (35.29)18.2507
2000's5 (29.41)29.6817
2010's3 (17.65)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
De Wit, LE; Hülsmann, WC; Schoonderwoerd, K; Stam, H1
Bollen, M; Stalmans, W1
Reuser, AJ; van Dongen, JM; Wisselaar, HA1
Reuser, AJ; Wisselaar, HA1
Ermert, P; Garman, EF; Johnson, LN; Mitchell, EP; Oikonomakos, NG; Vasella, AT; Withers, SG1
Depre, C; Hue, L1
Arai, M; Fujiwara, H; Fujiwara, T; Higashioka, M; Kariya, T; Minatoguchi, S; Takatsu, H; Takemura, G; Uno, Y; Yoshikuni, Y1
Arai, M; Fujiwara, H; Fujiwara, T; Hashimoto, K; Kariya, T; Kawasaki, M; Minatoguchi, S; Nishida, Y; Takemura, G; Uno, Y1
Andersson, U; Butters, TD; Dwek, RA; Platt, FM1
Arai, M; Fujiwara, H; Fujiwara, T; Hashimoto, K; Higashioka, M; Kumada, H; Kuwano, K; Minatoguchi, S; Nishida, Y; Takemura, G; Uno, Y; Wang, N1
Arai, M; Fujiwara, H; Fujiwara, T; Hashimoto, K; Hashimoto, Y; Minatoguchi, S; Nishida, Y; Takemura, G; Uno, Y; Wang, N; Wu, DJ1
Arai, M; Chen, XH; Fujiwara, H; Fujiwara, T; Hashimoto, K; Minatoguchi, S; Nishida, Y; Takemura, G; Uno, Y; Wang, N1
Andersson, U; Butters, TD; Dwek, RA; Platt, FM; Reinkensmeier, G1
Feng, J; Flanagan, JJ; Frascella, M; Guillen, D; Khanna, R; Lockhart, DJ; Lun, Y; Pellegrino, LJ; Soska, R; Valenzano, KJ1
Brignol, N; Dhulipala, R; Do, HV; Feng, J; Frascella, M; Garcia, A; Khanna, R; Lockhart, DJ; Lun, Y; Pellegrino, LJ; Powe, AC; Soska, R; Toth, MJ; Valenzano, KJ; Wustman, BA; Xu, S1
Do, HV; Feng, J; Frascella, M; Garcia, A; Gotschall, R; Khanna, R; Lun, Y; Martina, JA; Nair, A; Ponery, AS; Puertollano, R; Raben, N; Ralston, E; Schilling, A; Soska, R; Tuske, S; Valenzano, KJ; Valle, MCD; Xu, S1
Blair, HA1

Reviews

2 review(s) available for 1-deoxynojirimycin and glycogen

ArticleYear
An evaluation of the potential side-effects of alpha-glucosidase inhibitors used for the management of diabetes mellitus.
    European journal of clinical investigation, 1994, Volume: 24 Suppl 3

    Topics: 1-Deoxynojirimycin; Acarbose; Administration, Oral; Animals; Blood Glucose; Carbohydrate Sequence; Contraindications; Diabetes Mellitus; Diabetic Nephropathies; Glucosamine; Glycogen; Glycogen Storage Disease; Glycoproteins; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Molecular Sequence Data; Sucrase-Isomaltase Complex; Trisaccharides

1994
Cipaglucosidase Alfa: First Approval.
    Drugs, 2023, Volume: 83, Issue:8

    Topics: 1-Deoxynojirimycin; Adult; Enzyme Replacement Therapy; Glycogen; Glycogen Storage Disease Type II; Humans

2023

Other Studies

15 other study(ies) available for 1-deoxynojirimycin and glycogen

ArticleYear
Hormonal control of cardiac lipolysis by glyco(geno)lysis.
    Biochimica et biophysica acta, 1990, Nov-12, Volume: 1055, Issue:2

    Topics: 1-Deoxynojirimycin; Animals; Glucagon; Glucosamine; Glycerol; Glycogen; Glycolysis; Hypoxia; In Vitro Techniques; Lactates; Lipolysis; Myocardium; Rats

1990
The antiglycogenolytic action of 1-deoxynojirimycin results from a specific inhibition of the alpha-1,6-glucosidase activity of the debranching enzyme.
    European journal of biochemistry, 1989, May-15, Volume: 181, Issue:3

    Topics: 1-Deoxynojirimycin; 1,4-alpha-Glucan Branching Enzyme; Cytosol; Glucosamine; Glucose; Glucosyltransferases; Glycogen; Glycoside Hydrolase Inhibitors; Liver; Molecular Structure; Phosphorylation

1989
Effects of N-hydroxyethyl-1-deoxynojirimycin (BAY m 1099) on the activity of neutral- and acid alpha-glucosidases in human fibroblasts and HepG2 cells.
    Clinica chimica acta; international journal of clinical chemistry, 1989, Jun-15, Volume: 182, Issue:1

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Binding, Competitive; Carcinoma, Hepatocellular; Fibroblasts; Glucosamine; Glycogen; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Immunohistochemistry; Kinetics; Liver Neoplasms; Lysosomes; Microscopy, Electron; Molecular Weight; Tumor Cells, Cultured

1989
Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
    Biochemistry, 1996, Jun-11, Volume: 35, Issue:23

    Topics: 1-Deoxynojirimycin; Adenosine Monophosphate; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Enzyme Inhibitors; Glucosamine; Glycogen; Kinetics; Models, Molecular; Muscle, Skeletal; Phosphates; Phosphorylases; Protein Conformation; Rabbits; Tetrazoles

1996
Inhibition of glycogenolysis by a glucose analogue in the working rat heart.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:8

    Topics: 1-Deoxynojirimycin; Animals; Coronary Circulation; Depression, Chemical; Enzyme Inhibitors; Glucosamine; Glucose; Glycogen; Glycogen Debranching Enzyme System; Heart; Insulin; Lactates; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Perfusion; Rats; Rats, Wistar

1997
N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, markedly reduced infarct size in rabbit hearts.
    Circulation, 1998, Apr-07, Volume: 97, Issue:13

    Topics: 1-Deoxynojirimycin; Animals; Collateral Circulation; Enzyme Inhibitors; Glycogen; Glycoside Hydrolase Inhibitors; Hemodynamics; Lactic Acid; Male; Molecular Structure; Myocardial Infarction; Rabbits; Risk Factors

1998
A novel anti-diabetic drug, miglitol, markedly reduces myocardial infarct size in rabbits.
    British journal of pharmacology, 1999, Volume: 128, Issue:8

    Topics: 1-Deoxynojirimycin; Animals; Dose-Response Relationship, Drug; Glucosamine; Glycogen; Hemodynamics; Hypoglycemic Agents; Imino Pyranoses; Lactic Acid; Male; Myocardial Infarction; Myocardium; Rabbits

1999
N-butyldeoxygalactonojirimycin: a more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo.
    Biochemical pharmacology, 2000, Apr-01, Volume: 59, Issue:7

    Topics: 1-Deoxynojirimycin; Animals; Carbon Radioisotopes; Cell Division; Disaccharidases; Enzyme Inhibitors; Female; Glycogen; Glycosphingolipids; Humans; Liver; Lymphocytes; Mice; Mice, Inbred C57BL; Tissue Distribution

2000
Role of protein kinase C in the reduction of infarct size by N-methyl-1-deoxynojirimycin, an alpha-1,6-glucosidase inhibitor.
    British journal of pharmacology, 2001, Volume: 133, Issue:5

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Biological Transport; Enzyme Inhibitors; Glycogen; Glycoside Hydrolase Inhibitors; Isoenzymes; Lactates; Male; Myocardial Infarction; Myocardium; Protein Kinase C; Rabbits; Time Factors

2001
Combination of N-methyl-1-deoxynojirimycin and ischemic preconditioning markedly reduces the size of myocardial infarcts in rabbits.
    Japanese circulation journal, 2001, Volume: 65, Issue:7

    Topics: 1-Deoxynojirimycin; Animals; Combined Modality Therapy; Disease Models, Animal; Enzyme Inhibitors; Glycogen; Glycoside Hydrolase Inhibitors; Heart Ventricles; Ischemia; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardial Infarction; Rabbits

2001
N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, markedly improves postischemic left ventricular dysfunction.
    Heart and vessels, 2000, Volume: 15, Issue:6

    Topics: 1-Deoxynojirimycin; Adenosine Triphosphate; Animals; Blood Flow Velocity; Disease Models, Animal; Enzyme Inhibitors; Glycogen; Glycoside Hydrolase Inhibitors; Heart; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Sprague-Dawley; Time Factors; Ventricular Dysfunction, Left

2000
Inhibition of glycogen breakdown by imino sugars in vitro and in vivo.
    Biochemical pharmacology, 2004, Feb-15, Volume: 67, Issue:4

    Topics: 1-Deoxynojirimycin; Animals; Female; Glycogen; Glycoside Hydrolase Inhibitors; Mice; Mice, Inbred C57BL

2004
The pharmacological chaperone AT2220 increases recombinant human acid α-glucosidase uptake and glycogen reduction in a mouse model of Pompe disease.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Buffers; Disease Models, Animal; Enzyme Activation; Enzyme Stability; Glycogen; Glycogen Storage Disease Type II; Half-Life; Humans; Mice; Mice, Knockout; Protein Denaturation; Rats; Recombinant Proteins

2012
The pharmacological chaperone AT2220 increases the specific activity and lysosomal delivery of mutant acid alpha-glucosidase, and promotes glycogen reduction in a transgenic mouse model of Pompe disease.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: 1-Deoxynojirimycin; Administration, Oral; Animals; Biocatalysis; Biological Availability; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Endoplasmic Reticulum; Enzyme Stability; Gene Knockout Techniques; Glucan 1,4-alpha-Glucosidase; Glycogen; Glycogen Storage Disease Type II; Humans; Isoenzymes; Lysosomes; Mice; Mice, Transgenic; Mutant Proteins; Mutation; Protein Transport; Proteolysis

2014
Improved efficacy of a next-generation ERT in murine Pompe disease.
    JCI insight, 2019, 03-07, Volume: 4, Issue:5

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Disease Models, Animal; Enzyme Replacement Therapy; Female; Glycogen; Glycogen Storage Disease Type II; Humans; Lysosomes; Male; Mannosephosphates; Mice; Mice, Knockout; Muscle, Skeletal; Rats; Rats, Sprague-Dawley

2019