1-deoxynojirimycin has been researched along with glucosamine in 401 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 164 (40.90) | 18.7374 |
| 1990's | 140 (34.91) | 18.2507 |
| 2000's | 63 (15.71) | 29.6817 |
| 2010's | 29 (7.23) | 24.3611 |
| 2020's | 5 (1.25) | 2.80 |
| Authors | Studies |
|---|---|
| Benjamin, ER; Boyd, RE; Khanna, R; Lee, G; Rybczynski, P; Valenzano, KJ; Wustman, BA | 1 |
| Aerts, GM; Claeyssens, M; de Bruyne, CK; de Gussem, RL | 1 |
| Ariki, M; Fukui, T | 1 |
| Chida, N; Furuno, Y; Ikemoto, H; Ogawa, S | 1 |
| Rabouille, C; Spiro, RG | 1 |
| Chan, PY; Springer, TA | 1 |
| Holland, PC; Trudel, GC | 3 |
| Hotchin, NA; Watt, FM | 1 |
| Furui, H; Hasegawa, A; Kiso, M | 1 |
| Buléon, A; Pérez, S; Raimbaud, E | 1 |
| Jacob, GS; Karlsson, GB; Platt, FM | 1 |
| Falchetto, R; Keller, P; Legler, G; Semenza, G; Wacker, H | 1 |
| Frydas, A; Ladas, SD; Papadopoulos, A; Raptis, SA | 1 |
| Dimitriadis, G; Raptis, S | 1 |
| Ben-Zeev, O; Carroll, R; Doolittle, MH; Severson, DL | 1 |
| Kingma, PJ; Menheere, PP; Nieuwenhuijzen Kruseman, AC; Sels, JP | 1 |
| Dishon, DS; Ferrell, GA; Le, A; Le, QQ; Sifers, RN | 1 |
| Dokhélar, MC; Pham, D; Pique, C; Tursz, T | 1 |
| Grässel, S; Hasilik, A | 1 |
| Parsons, PG; Takahashi, H | 1 |
| Moore, SE; Spiro, RG | 2 |
| Deas, J; Erecińska, M; Silver, IA | 1 |
| Inoue, S; Simoni, RD | 1 |
| Balwierz, PS; Gad, SC; Guzzie, PJ; Oshiro, Y; Rohrbacher, E; Soelter, SG | 1 |
| Boustany, RM; Daniel, PF; Sauls, DL | 1 |
| Hori, Y; Imokawa, G; Kubota, Y; Shimada, S; Tsukamoto, K; Uno, A | 1 |
| Bolscher, J; Ploegh, H; Tan, A; van Boeckel, S; van den Broek, L | 1 |
| Bowlin, TL; Kang, MS; Liu, PS; Sunkara, PS; Taylor, DL; Tyms, AS | 1 |
| el Battari, A; Forget, P; Fouchier, F; Pic, P | 1 |
| Ahrens, K; Arends, J; Lübke, D; Willms, B | 1 |
| Ray, MK; Stanley, P; Sundaram, S; Yang, J | 1 |
| Renkonen, R; Ustinov, J | 1 |
| DeBouno, JF; Michaelis, OE; Szepesi, B; Tulp, OL | 1 |
| Fenouillet, E; Gluckman, JC | 1 |
| Kaluza, G; McDowell, W; Repges, S | 1 |
| Dedera, D; Ratner, L; vander Heyden, N | 2 |
| Smith, ME | 1 |
| Creutzfeldt, W; Lamberts, R; Lembcke, B; Wöhler, J | 1 |
| Creutzfeldt, W; Ebert, R; Fölsch, UR; Gatzemeier, W; Lembcke, B; Siegel, E | 1 |
| Creutzfeldt, W; Ebert, R; Fölsch, UR; Gatzemeier, W; Lembcke, B; Lücke, B; Siegel, E | 1 |
| Bause, E; Gross, A; Schweden, J | 1 |
| Fujimoto, K; Kornfeld, R | 1 |
| Cazzulo, JJ; Gañán, S; Parodi, AJ | 1 |
| Damen, JE; Greenberg, AH; Jamieson, JC; Kolodka, T; Spearman, MA; Wright, JA | 1 |
| Gañán, S; Gotz, G; Parodi, AJ | 1 |
| Duprat, AM; Gualandris-Parisot, L; Maurel, P; Teissie, J | 1 |
| Blanchette-Mackie, EJ; Masuno, H; Mateo, C; Park, JW; Schultz, CJ; Scow, RO | 1 |
| Kimura, Y; Suehisa, H; Takagi, S; Yamaguchi, O | 1 |
| Doskoch, PM; Houghton, AN; Vijayasaradhi, S | 1 |
| Schwarz, RT | 1 |
| Aubery, M; Bauvy, C; Codogno, P; Darmoul, D; Ogier-Denis, E; Sapin, C; Trugnan, G | 1 |
| Haeuw, JF; Michalski, JC; Montreuil, J; Strecker, G; Wieruszeski, JM | 1 |
| Bird, MM; Carroll, M | 2 |
| Howard, SC; Welply, JK; Wittwer, AJ | 1 |
| Holman, RR; Steemson, J; Turner, RC | 1 |
| Jacob, GS; Jones, IM | 1 |
| Toeller, M | 1 |
| Kawashima, S; Kengaku, M; Nakane, M | 1 |
| Inoue, S; Shishido, T | 1 |
| Alexopoulos, E; Dimitriadis, G; Ganotakis, M; Hatziagellaki, E; Komesidou, V; Kordonouri, O; Raptis, S | 1 |
| Clarke, AJ | 1 |
| Ishii, S; Volpe, JJ | 1 |
| Hering, TM; Sandell, LJ | 1 |
| Baines, S; Barker, C; Fleet, G; Jacob, GS; Namgoong, SK; Winchester, B | 1 |
| Forsee, WT; Schutzbach, JS | 1 |
| Franc, JL; Giraud, A; Lanet, J | 1 |
| Aubery, M; Codogno, P; Ogier-Denis, E; Sapin, C; Trugnan, G | 1 |
| Elbein, AD; Kaushal, GP; Pastuszak, I; Szumilo, T | 1 |
| Baldwin, SA; Bramwell, ME; Davies, A | 1 |
| Burgemeister, R; Danescu, I; Gutensohn, W | 1 |
| DiCioccio, RA; Mahoney, CM | 1 |
| Buchmeier, MJ; Burns, JW; Spiro, RC; Wright, KE | 1 |
| Grabowski, GA; Greenberg, P; Liotta, DC; Merrill, AH | 1 |
| Davis, RJ; Weis, FM | 1 |
| Bruyneel, EA; De Mets, M; Di Virgilio, S; Dragonetti, CH; Hooghe, RJ; Mareel, MM | 1 |
| Kabakoff, B; Lennarz, WJ | 1 |
| Akazawa, T; Arata, Y; Hanzawa, H; Hayashi, M; Mitsui, T; Takahashi, N; Tsuru, A | 1 |
| Elbein, AD; Kaushal, GP; Mitchell, M; Tropea, JE | 1 |
| Bernotas, RC; Ganem, B | 1 |
| Dubin, A; Guzdek, A; Potempa, J; Travis, J | 1 |
| Das, M; Khire, J | 1 |
| De Wit, LE; Hülsmann, WC; Schoonderwoerd, K; Stam, H | 1 |
| Kitamura, T; Morikawa, S; Shimizu, H; Tsuchie, H; Tsuruoka, T; Ushijima, H; Yamamoto, H; Yoshida, K | 1 |
| Franc, JL; Giraud, A; Long, Y | 1 |
| Atsumi, S; Iinuma, H; Nosaka, C; Umezawa, K | 1 |
| Jansen, H; Verhoeven, AJ | 1 |
| Fellows, LE; Fleet, GW; Winchester, B | 1 |
| Bloom, SR; Requejo, F; Uttenthal, LO | 1 |
| Berzin, M; Diamond, TH; Griffiths, RF; Kalk, WJ; Osler, CE; Smit, AM; Wing, J | 1 |
| Foukaridis, GN; Joubert, PH; Venter, HL | 1 |
| Heagerty, AM; MacIver, DH; McNally, PG; Ollerenshaw, JD; Sheldon, TA | 1 |
| Honma, H; Kitamura, T; Shimizu, H; Tsuchie, H; Tsuruoka, T; Ushijima, H; Yoshida, K | 1 |
| Creutzfeldt, W; Diederich, M; Fölsch, UR; Lembcke, B | 1 |
| Decker, K; Gerok, W; Gross, V; Häussinger, D; Heinrich, PC; Steube, K; Tran-Thi, TA | 1 |
| Creutzfeldt, W; Fehmann, HC; Fölsch, UR; Göke, B; Siegel, EG | 1 |
| Fukuda, M; Guan, JL; Rose, JK | 1 |
| Burnside, J; Gesundheit, N; Ronin, C; Stannard, BS; Weintraub, BD | 1 |
| Mitchell, WM; Montefiori, DC; Robinson, WE | 1 |
| Gerok, W; Giffhorn-Katz, S; Gross, V; Heinrich, PC; Katz, NR; Kreisel, W; Ludolph, D | 1 |
| Lehrman, MA; Zeng, Y | 1 |
| Olivecrona, T; Semb, H | 1 |
| Collins, C; Davis, AC; Shulman, MJ | 1 |
| Matlin, KS; Roth, MG; Skibbens, JE | 1 |
| Andus, T; Castell, J; Gerok, W; Gross, V; Heinrich, PC; Vom Berg, D | 1 |
| Broxterman, HJ; Lindhout, J; Neefjes, JJ; Ploegh, HL; van Boom, JH; van der Marel, GA | 1 |
| Bansal, DD; MacGregor, RR | 1 |
| Bollen, M; Stalmans, W | 1 |
| Covarrubias, M; Kopta, C; Steinbach, JH | 1 |
| Franc, JL; Giraud, A | 1 |
| Ardail, D; Levrat, C; Louisot, P; Morelis, R | 1 |
| Sergio, W | 1 |
| Keenan, TW; Valivullah, HM | 1 |
| Hauri, HP; Matter, K; McDowell, W; Schwartz, RT | 1 |
| Belard, M; Cacan, R; Lepers, A; Verbert, A | 1 |
| Akiyama, SK; Yamada, KM; Yamada, SS | 1 |
| Gesundheit, N; Gyves, PW; Ronin, C; Stannard, BS; Thotakura, NR; Weintraub, BD | 1 |
| Andaluz, E; Larriba, G; Muñoz, MD; Ridruejo, JC | 1 |
| Byers, LD; Li, YK | 1 |
| Daniel, PF; Fleet, GW; Newburg, DS; O'Neil, NE; Smith, PW | 1 |
| Gottschalk, S; von Figura, K; Waheed, A | 1 |
| Hoke, GM; Pal, R; Sarngadharan, MG | 1 |
| Hoke, GM; Kalyanaraman, VS; Pal, R; Sarngadharan, MG | 1 |
| Reuser, AJ; van Dongen, JM; Wisselaar, HA | 1 |
| Asano, N; Furumoto, T; Kameda, Y; Matsui, K | 1 |
| Madar, Z | 2 |
| Gray, RS; Hillman, RJ; Scott, M | 1 |
| Klauser, RM; Prager, RJ; Schernthaner, G; Schnack, C; Schneider, BG; Winkler, J | 1 |
| Heinz, G; Komjati, M; Korn, A; Waldhäusl, W | 1 |
| Broxterman, HJ; Neefjes, JJ; Ploegh, HL; van Boom, JH; van der Marel, GA; Verkerk, JM | 1 |
| Insel, PA; Terman, BI | 1 |
| Geering, K; Rossier, BC; Zamofing, D | 1 |
| Bell, EA; Berrie, EM; Davis, JM; Hegarty, MP; Jeffries, DJ; Mobberley, MA; Nash, RJ; Ryder, TA; Taylor, DL; Tyms, AS | 1 |
| Takatsuki, A; Tamura, G | 1 |
| Hillebrand, I; Joubert, HF; Joubert, PH; Venter, CP | 1 |
| Bause, E; Hasilik, A; Legler, G; Lemansky, P; Nauerth, A; von Figura, K | 1 |
| Legler, G; Liedtke, H | 1 |
| Bischoff, J; Kornfeld, R; Liscum, L | 1 |
| Mercurio, AM | 1 |
| Bouchilloux, S; Fayet, G; Franc, JL; Hovsepian, S | 1 |
| Bause, E; Legler, G; Schweden, J | 1 |
| Bause, E; Borgmann, C; Legler, G; Schweden, J | 1 |
| Burns, G; Conary, J; Hasilik, A; Nauerth, A; von Figura, K | 1 |
| Boas, S; Desnick, RJ; Dinur, T; Fabbro, D; Gatt, S; Grabowski, GA; Legler, G; Osiecki-Newman, KM | 1 |
| Barnhoorn, M; Bause, E; Ploegh, H; Tulp, A | 1 |
| Herscovics, A; Romero, PA | 2 |
| Hashimoto, M; Setoi, H; Takeno, H | 1 |
| Lindstrom, J; Merlie, JP; Schlesinger, S; Smith, MM | 1 |
| Jamieson, JC; Spearman, MA; Wright, JA | 1 |
| Decker, K; Elbein, AD; Gross, V; Heinrich, PC; Schwarz, RT; Tran-Thi, TA | 1 |
| Herscovics, A; Holland, PC | 1 |
| Aerts, JM; Barranger, JA; Brul, S; Donker-Koopman, WE; Murray, GJ; Schram, AW; Tager, JM; van Weely, S | 1 |
| Hillebrand, I; Omar, MA; Seedat, MA | 1 |
| Elbein, AD; Hori, H; Pan, YT | 1 |
| Cacan, R; Cecchelli, R; Verbert, A | 1 |
| Desnick, RJ; Fabbro, D; Grabowski, GA; Legler, G; Osiecki-Newman, K | 1 |
| Böshagen, H; Heiker, FR; Schüller, AM | 1 |
| Gavériaux, C; Loor, F | 1 |
| Arakaki, RF; Collier, E; Gorden, P; Hedo, JA | 1 |
| Datema, R; McDowell, W; Romero, PA; Schwarz, RT | 1 |
| Bowlin, TL; Liu, PS; Sjoerdsma, A; Sunkara, PS | 1 |
| Orkin, SH; Sytkowski, AJ; Wojchowski, DM | 1 |
| Connolly, JA; Simard, G | 1 |
| Bause, E; Foddy, L; Hughes, RC | 1 |
| Goda, T; Koldovský, O; Lee, SM; Samulitis, BK | 1 |
| Bieberich, E; Legler, G | 1 |
| Bollen, M; Stalmans, W; Vandebroeck, A | 1 |
| Scott, AR; Tattersall, RB | 1 |
| Massagué, J; Teixidó, J | 1 |
| Beuth, J; Ko, HL; Ohshima, Y; Pulverer, G; Roszkowski, K; Uhlenbruck, G; Yassin, A | 1 |
| Touster, O; Tulsiani, DR | 1 |
| Neefjes, JJ; Ploegh, HL | 1 |
| Kornfeld, R; Rizzolo, LJ | 1 |
| Bollini, R; Fabbrini, MS; Vitale, A; Zoppè, M | 1 |
| Bourbouze, R; Donsimoni, R; Lalegerie, P; Legler, G | 1 |
| Jamieson, JC | 1 |
| Gillette, RW; Long, CG; McKearn, TJ; Rodwell, JD; Simonson, RB; Ultee, ME | 1 |
| Banerjee, DK; Baum, BJ; Grant, SR; Kousvelari, EE | 1 |
| Ezure, Y; Itoh, M; Konno, K; Miyazaki, K; Nakamura, T; Ojima, N; Sugiyama, M; Yamada, N | 1 |
| Aoyagi, Y; Enomoto, H; Ezure, Y; Yoshikuni, Y | 1 |
| Bhat, NR | 1 |
| Koblet, H; Naim, HY | 1 |
| Overton, J | 1 |
| Kim, SC; Raushel, FM | 1 |
| Herscovics, A; Holland, PC; Trudel, GC | 1 |
| Bosch, JV; Legler, G; McDowell, W; Schwarz, RT; Tlusty, A | 1 |
| Boschek, CB; Niemann, H; Repp, R; Schwarz, RT; Tamura, T; Wege, H | 1 |
| Rogers, OC; Snider, MD | 1 |
| Hakomori, S; Herscovics, A; Manger, R; Nichols, EJ; Rohrschneider, LR | 1 |
| Hirani, S; Kong, N; Lodish, HF; Rasmussen, J | 1 |
| Grose, C; Montalvo, EA | 1 |
| Alberti, KG; Samad, AH; Taylor, R; Ty Willing, TS | 1 |
| Holt, PR; Kotler, DP; Thea, D; Yang, MY | 1 |
| Federlin, K; Hillebrand, I; Laube, H | 1 |
| Bezerra, J; Bustamante, S; Flores, C; Goda, T; Koldovský, O; Lee, SM | 1 |
| Granato, DA; Neeser, JR | 1 |
| Kubicek, CP | 1 |
| Dimitriadis, G; Hatziagelaki, E; Hillebrand, I; Ladas, S; Linos, A; Raptis, S | 1 |
| Friedlander, P; Herscovics, A; Romero, PA | 1 |
| Herscovics, A; Romero, PA; Saunier, B | 1 |
| Gee, SL; Koyama, AH; Malfer, C; Schlesinger, MJ; Schlesinger, S | 1 |
| Evans, SV; Fellows, L; Friedlander, P; Herscovics, A; Romero, PA | 1 |
| Bause, E; Hart, GW; Legler, G; Molyneux, RJ; Powell, LD | 1 |
| Bause, E; Fuhrmann, U; Ploegh, H | 1 |
| Decker, K; Gerok, W; Gross, V; Heinrich, PC; McDowell, W; Schwarz, RT; Steube, K; Tran-Thi, TA | 1 |
| Cañizo, JF; Hillebrand, I; Navascués, I; Sabán, J; Serrano-Rios, M | 1 |
| Gerich, JE; Kennedy, FP | 2 |
| Gerard, J; Hillebrand, I; Lefèbvre, PJ | 1 |
| Creutzfeldt, W; Fölsch, UR; Lembcke, B; Löser, C; Wöhler, J | 1 |
| Gerich, JE; Heiling, V; Kennedy, FP; Miles, JM | 1 |
| Boehme, K; Graefe, KH; Hillebrand, I; Wehling, K | 1 |
| Cauderay, M; Felber, JP; Hillebrand, I; Jéquier, E; Tappy, L; Temler, E | 1 |
| Bam, WJ; Joubert, PH; Manyane, N | 1 |
| Dimitriadis, G; Halvatsiotis, P; Hatziagelaki, E; Hillebrand, I; Ladas, S; Mitrakou, A; Raptis, A; Raptis, S | 1 |
| Luger, A; Röggla, G; Schernthaner, G; Schnack, C | 1 |
| Anastasopoulou, K; Frangaki, D; Hillebrand, I; Katsilambros, N; Marangos, M; Philippides, P; Protopapas, J; Siskoudis, P; Toskas, A; Xefteri, H | 1 |
| Arends, J; Willms, BH | 1 |
| Bopape, ML; Foukaridis, GN; Joubert, PH | 1 |
| Bachmann, W; Hillebrand, I; Lotz, N; Rinninger, F | 1 |
| Madar, Z; Olefsky, J | 1 |
| Barker, HM; Bowey, EA; Canfield, JE; Taylor, RH | 1 |
| Inouye, S; Kodama, Y; Niwa, T; Tsuruoka, T | 1 |
| Creutzfeldt, W; Fölsch, UR; Lembcke, B | 1 |
| Bounias, M | 1 |
| Herscovics, A; Kilker, RD; Quaroni, A; Saunier, B; Tkacz, JS | 1 |
| Bause, E; Hettkamp, H; Legler, G | 2 |
| Fiehn, NE; Moe, D | 1 |
| Hoover, CI; Newbrun, E; Walker, GJ | 1 |
| Andus, T; Decker, K; Gross, V; Heinrich, PC; Schwarz, RT; Tran-Thi, TA | 1 |
| Bause, E; Claesson, L; Legler, G; Peterson, P; Peyrieras, N; Ploegh, H; Vasilov, R | 1 |
| Elbein, AD | 1 |
| Bause, E; Burke, B; Legler, G; Matlin, K; Peyrieras, N; Ploegh, H | 1 |
| Kong, N; Lodish, HF | 1 |
| Mersmann, G; Ziegler, C | 1 |
| Gieselmann, V; Hasilik, A; Lemansky, P; von Figura, K | 1 |
| Kopec, LK; Stein, DC; Yasbin, RE; Young, FE | 1 |
| Bischoff, J; Kornfeld, R | 1 |
| Elbein, AD; Legler, G; McDowell, W; Schwarz, R; Tlusty, A | 1 |
| Bosch, JV; Schwarz, RT | 1 |
| Malfer, C; Schlesinger, MJ; Schlesinger, S | 1 |
| Honnen, WJ; Li, JS; Pinter, A | 1 |
| Hanozet, G; Oesch, B; Pircher, HP; Semenza, G; Vanni, P | 1 |
| Felgenhauer, B; Trautner, K | 1 |
| Hiromi, K; Miyata, S; Murao, S; Ohnishi, M; Tanaka, A | 1 |
| Goi, H; Inouye, S; Itoh, J; Kodama, Y; Niida, T; Niwa, T; Nobe, M; Ogawa, Y; Tsuruoka, T; Yamada, Y | 1 |
| Datema, R; Romero, PA; Schwarz, RT | 1 |
| Bosch, FX; Legler, G; Orlich, M; Rott, R; Schwarz, RT | 1 |
| Chambers, JP; Elbein, AD; Williams, JC | 1 |
| Nicolás, G; Valle, T | 1 |
| Lundquist, I; Salehi, A | 4 |
| Chang, J; Chrest, FJ; Mueller, RA; Partis, RA; Passaniti, A; Pili, R | 1 |
| Bozza, M; Corgiat-Mansin, L; Cravero, F; Giorda, C; Marena, S; Pagano, G; Rossi, CM | 1 |
| Reuser, AJ; Wisselaar, HA | 1 |
| Bischoff, H | 1 |
| Asano, N; Kizu, H; Matsui, K; Oseki, K; Tomioka, E | 1 |
| Branolte, JH; Kingma, PJ; Menheere, PP; Nieuwenhuijzen Kruseman, AC; Sels, JP; Wolffenbuttel, BH | 1 |
| Coniff, RF; Hoogwerf, BJ; Johnston, PS; Krol, A; Pi-Sunyer, FX; Santiago, JV | 1 |
| Tattersall, R | 1 |
| DeBouno, JF; Michaelis, OE; Tulp, OL | 1 |
| Fukuyasu, H; Inouye, S; Ishii, M; Shibahara, S; Tsuruoka, T; Usui, T | 1 |
| Lundquist, I; Panagiotidis, G; Salehi, A | 1 |
| Ermert, P; Garman, EF; Johnson, LN; Mitchell, EP; Oikonomakos, NG; Vasella, AT; Withers, SG | 1 |
| Kawahata, T; Kawashima, K; Kinumaki, A; Kohno, J; Komatsubara, S; Mori, H; Morimoto, M; Nishio, M; Otake, T; Ueba, N | 1 |
| Johnson, AB; Taylor, R | 1 |
| Duursema, L; Groenewoud, G; Hundt, HK; Middle, MV; Müller, FO; Schall, R | 1 |
| Menheere, PP; Nauta, JJ; Nieuwenhuijzen Kruseman, AC; Sels, JP; Wolffenbuttel, BH | 1 |
| Campillo, JE; Martinez, IM; Nieto, M; Ropero, MF; Tormo, MA | 2 |
| Asano, N; Elbein, AD; Nash, RJ; Pan, YT; Zeng, Y | 1 |
| Berlin, C; Feig, PU; Petzinna, D; Ratzmann, KP; Rybka, J; Schernthaner, G; Segal, P | 1 |
| Ahr, HJ; Boberg, M; Brendel, E; Krause, HP; Steinke, W | 1 |
| Depre, C; Hue, L | 1 |
| Choi, SY; Chung, HH; Jeong, S; Moon, KD; Park, H; Schultz, PG; Youn, HJ; Yu, J | 1 |
| Coniff, RF; Davidson, JA; Feig, PU; Haffner, SM; Johnston, PS; Krol, A | 1 |
| Coniff, RF; Feig, PU; Johnston, PS; Kelley, DE; Krol, A; Mooradian, AD | 1 |
| Coniff, RF; Johnston, PS; Lebovitz, HE; Munera, CL; Raskin, P; Simonson, DC | 1 |
| Bauer, RJ; Mitrakou, A; Raptis, AE; Raptis, SA; Schulz, H; Tountas, N | 1 |
| Chiasson, JL; Rabasa-Lhoret, R | 1 |
| Lardinois, CK | 1 |
| Mooradian, AD; Thurman, JE | 1 |
| Axen, KV; Li, X; Sclafani, A | 1 |
| Chang, H; Gerdeman, MS; Hines, JV; Warn, DE | 1 |
| Kajikawa, H; Masaki, S | 1 |
| Dolphin, PJ; Graham, SE; Russell, JC | 1 |
| Rowe, PM | 1 |
| Andres, E; Blicklé, JF; Brogard, JM | 1 |
| Arai, M; Fujiwara, H; Fujiwara, T; Hashimoto, K; Kariya, T; Kawasaki, M; Minatoguchi, S; Nishida, Y; Takemura, G; Uno, Y | 1 |
| Riddle, MC | 1 |
| Scott, LJ; Spencer, CM | 1 |
| Stadler, HJ | 1 |
| Fehmann, HC | 4 |
| Kuritzky, L; Quillen, DM; Samraj, G | 1 |
| Carlson, RF | 1 |
| Compain, P; Martin, OR; Masson, G | 1 |
| Chiou, WL; Chung, SM; Jeong, HY; Ma, C; Wu, TC | 1 |
| Baker, DE; Campbell, LK; Campbell, RK | 1 |
| Huijberts, MS; Sels, JP; Wolffenbuttel, BH | 1 |
| Hanefeld, M; Naditch, L; Raptis, SA; Rybka, J; Schernthaner, G; Standl, E | 1 |
| Chiasson, JL; Naditch, L | 1 |
| Laws, A | 1 |
| Bols, M; Bülow, A; Liang, X; Liu, H; Søhoel, H | 1 |
| Arai, M; Chen, XH; Fujiwara, H; Hashimoto, K; Hashimoto, Y; Minatoguchi, S; Takemura, G; Uno, Y; Wang, N | 1 |
| Branza-Nichita, N; Butters, TD; Carrouée-Durantel, S; Durantel, D; Dwek, RA; Zitzmann, N | 1 |
| Maislos, M; Rybka, J; Schernthaner, G; Segal, P; Van Gaal, L | 1 |
| Lefèbvre, PJ; Scheen, AJ | 1 |
| Dhavale, DD; John, S; Patil, NT; Sabharwal, SG | 1 |
| Neye, H | 1 |
| Drent, ML; Hoenderdos, EB; Jonker, JJ; Tollefsen, AT; van der Veen, EA; van Heusden, FH | 1 |
| Horowitz, M; Lee, A; Morley, JE; Patrick, P; Wishart, J | 1 |
| Artés, M; Benito, P; Faure, E; García-Mayor, R; López, JS; Mesa, J; Pallardo, LF; Puig-Domingo, M; Ravella, R | 1 |
| Compain, P; Godin, G; Martin, OR; Masson, G | 1 |
| Asano, N; Kato, A; Watson, AA | 1 |
| Deppenmeier, U; Hoffmeister, M; Prust, C | 1 |
| Chawla, S; Takiya, L | 1 |
| Nishimura, Y | 1 |
| Block, TM; Dwek, RA; Jacob, G; Jordan, R; Lu, X; Mehta, A; Moriarty, RM; Ouzounov, S; Simsek, E | 1 |
| Fischer, S; Hanefeld, M | 1 |
| Cerè, V; Pollicino, S; Ricci, A | 1 |
| Scheen, AJ | 1 |
| Compain, P; Godin, G; Martin, OR | 1 |
| Chang, CF; Chen, JS; Lin, CH; Wong, CH; Wu, CY | 1 |
| Aller, R; Conde Valentín, R; de Luis Román, DA; del Pozo García, E; Romero Bobillo, E | 1 |
| Haslbeck, M; Jakob, S; Kellerer, M; Linn, T | 1 |
| Arai, M; Chen, X; Fujiwara, H; Fujiwara, T; Lu, C; Minatoguchi, S; Takemura, G; Uno, Y; Wang, N | 1 |
| Dhavale, DD; Karanjule, NS; Markad, SD; PrakashaReddy, J | 1 |
| Butters, TD; Callaghan, R; Dwek, RA; Norris-Cervetto, E; Platt, FM | 1 |
| Chang, CF; Chao, TA; Ho, CW; Lin, CH; Wong, CH; Wu, CY | 1 |
| Steiner, AJ; Stütz, AE | 1 |
| Crews, P; Segraves, NL | 1 |
| Chiba, S; Hakamata, W; Kadokura, K; Kimura, A; Muroi, M; Nishio, T; Oku, T; Takatsuki, A | 1 |
| Asano, N; Compain, P; Goujon, JY; Gueyrard, D; Ikeda, K; Kato, A; Martin, OR | 1 |
| Akkermans, RP; Lucassen, PL; Rutten, GE; Van de Laar, FA; Van de Lisdonk, EH; Van Weel, C | 1 |
| Arai, M; Chen, XH; Fujiwara, H; Hashimoto, K; Lu, C; Minatoguchi, S; Takemura, G; Uno, Y; Wang, N | 1 |
| Defoin, A; Dubernet, M; Tarnus, C | 1 |
| Clardy, J; Lobkovsky, E; Shimizu, Y; Suzuki, H; Thammana, S | 1 |
| Hayashi, I; Kuboyama, N; Yamaguchi, T | 1 |
| Chang, CF; Ho, CW; Li, ST; Li, YK; Lin, CH; Lin, YN; Liu, SW; Wu, CY; Wu, YT | 1 |
| Bols, M; Ortega-Caballero, F; Qing, FL; Qiu, XL; Wang, RW | 1 |
| Blattner, R; Furneaux, RH; Pakulski, Z | 1 |
| Boosi, R; Kandikere, VN; Maurya, S; Mudigonda, K; Nirogi, RV; Shukla, M; Yerramilli, A | 1 |
| Adachi, I; Asano, N; Compain, P; Godin, G; Ikeda, K; Kato, A; Martin, O; Yu, L | 1 |
| Bement, WJ; Dwyer, BE; Kitzmiller, TJ; Sinclair, JF; Yohe, HC | 1 |
| Eto, Y | 1 |
| Bartosch, B; Chapel, C; Cosset, FL; Dubuisson, J; Durantel, D; Dwek, RA; Garcia, C; Roingeard, P; Trépo, C; Zitzmann, N; Zoulim, F | 1 |
| Branza-Nichita, N; Dwek, RA; Hussey, M; Michelet, M; Smith, C; Woodhouse, SD; Zitzmann, N | 1 |
| Diot, J; García-Moreno, MI; Gouin, SG; Haupt, K; Kovensky, J; Ortiz Mellet, C | 1 |
| Ge, G; Hu, Y; Liu, H; Liu, Y; Luan, H; Yang, L; Zhang, Y; Zhou, K | 1 |
| Aghajari, N; Haser, R; Mattes, R; Ravaud, S; Robert, X; Watzlawick, H | 1 |
| Etou, Y | 1 |
| Ishikawa, T; Koshiba, S; Nakagawa, H; Tamura, A; Toyoda, Y; Wakabayashi-Nakao, K | 1 |
| Cardona, F; Cipolla, L; Forcella, M; Fusi, P; Goti, A; Gregori, M; Parenti, P; Parmeggiani, C; Schirone, R | 1 |
| Bezouska, K; Catelani, G; D'Andrea, F; Griselli, A; Guazzelli, L; Kren, V; Krenek, K; Nemcová, P | 1 |
| Mohan, S; Pinto, BM; Rose, DR; Sim, L | 1 |
| Raybould, HE; Sharp, JW; Vincent, KM | 1 |
| Clark, LF; Horenstein, NA; Johnson, JV | 1 |
| Ding, C; Douglas, DJ; Kang, Y; Terrier, P | 1 |
| Shang, Q; Tang, YL; Xiang, JF | 1 |
| Imokawa, G; Nakajima, H; Wakabayashi, Y | 1 |
| Block, TM; Chang, J; Cuconati, A; Du, Y; Gill, T; Guo, F; Guo, JT; Wang, L; Xu, X; Ye, H | 1 |
| Alonzi, DS; Ardes-Guisot, N; Baron, A; Blériot, Y; Butters, TD; Désiré, J; Howe, JD; Lee, MJ; Smith, N; Sollogoub, M; Vauzeilles, B | 1 |
| Block, TM; Chang, J; Cuconati, A; Du, Y; Gill, T; Guo, F; Guo, JT; Khan, N; Wang, L; Xu, X; Ye, H | 1 |
| Funasaka, Y; Ito, M; Katagata, Y; Mikami, M; Sonoki, T; Suzuki, T | 1 |
| Danisuddin, M; Hasan, S; Khan, AU; Singh, K; Verma, PK | 1 |
| Aguilar, AL; Butters, TD; Escribano, J; Wentworth, P | 1 |
| Ji, DF; Li, YG; Lin, TB; Lv, ZQ; Zhong, S | 1 |
| Adachi, I; Asano, N; Cha, JK; Fleet, GW; Hirokami, Y; Hollinshead, J; Kato, A; Kiappes, JL; Kinami, K; Miyawaki, S; Molyneux, RJ; Nash, RJ; Tsuji, Y; Zitzmann, N | 1 |
| Bols, M; Kilså, K; Laursen, BW; Lindbäck, E; Pedersen, CM; Poulsen, JC | 1 |
| Aerts, JM; Bonger, KM; Codée, JD; Donker-Koopman, WE; Ferraz, MJ; Ghisaidoobe, AB; Hoogendoorn, S; Houben, J; Overkleeft, HS; Strijland, A; van den Berg, RJ; van der Marel, GA; van Rijssel, ER; Wennekes, T | 1 |
| Bouckaert, J; Brissonnet, Y; Delplace, F; Fabre, E; Gouin, SG; Guérardel, Y; Hurtaux, T; Mallet, JM; Sendid, B; Sfihi-Loualia, G | 1 |
| Bols, M; Fernández-Bolaños, JG; López, Ó; Olsen, JI; Padrón, JM; Plata, GB | 1 |
| Chen, W; Nie, H; Zhao, K; Zhou, G | 1 |
| Fukui, K; Hatano, A; Iwaki, R; Kanno, Y; Kato, A; Kondo, Y; Okada, M; Sunaga, Y; Umezawa, H; Yamada, H | 1 |
| Harusawa, S; Kawahata, R; Mizuki, K; Sekine, A; Shibano, M; Usami, Y; Yoneyama, H | 1 |
| Fernández, JMG; García-Moreno, MI; Higaki, K; Martin, NI; Mellet, CO; Mena-Barragán, T; Nanba, E; Okazaki, T; Pieters, RJ; Sevšek, A | 1 |
| Dural, E; Eruygur, N | 1 |
| Kitamura, T; Okuyama, M; Takahashi, D; Toshima, K | 1 |
| Ballereau, S; Bodlenner, A; Castellan, T; Compain, P; Dehoux, C; Génisson, Y; Lepage, ML; Liang, Y; Rodriguez, F; Santos, C | 1 |
| Li, M; Li, XL; Liu, YX; Peng, YT; Wang, KR; Yang, JX; Zhang, HX | 1 |
| Cao, ZR; Li, JJ; Li, M; Li, RF; Li, XL; Wang, KR; Yang, JX; Zhang, HX | 1 |
| Adachi, I; Fleet, GWJ; Hata, M; Hirono, S; Kato, A; Nakagome, I; Nash, RJ; Natori, Y; Yoshimura, Y | 1 |
| Chen, JG; Lin, P; Nie, XL; Peng, DY; Wang, XQ; Yin, ZP; Yuan, E; Zeng, JC | 1 |
| Chung, WH; Jung, DH; Lee, H; Seo, DH; Seo, MJ | 1 |
| Ai, GM; Cao, ZR; Chen, SB; Li, RF; Li, XL; Liu, J; Wang, KR; Xu, LY; Yang, JX; Zhang, HX; Zhang, HY | 1 |
30 review(s) available for 1-deoxynojirimycin and glucosamine
| Article | Year |
|---|---|
Pharmacological chaperones as therapeutics for lysosomal storage diseases.
Topics: Cell Line; Glycolipids; Humans; Lysosomal Storage Diseases; Molecular Chaperones; Structure-Activity Relationship | 2013 |
alpha-Glucosidase inhibition in the treatment of diabetes mellitus.
Topics: 1-Deoxynojirimycin; Acarbose; Diabetes Mellitus; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Reference Values; Trisaccharides | 1992 |
Manipulation of the biosynthesis of protein-modifying glycoconjugates by the use of specific inhibitors.
Topics: 1-Deoxynojirimycin; Animals; Carbohydrate Sequence; Glucosamine; Glucosidases; Glycoconjugates; Glycosylation; Indolizines; Molecular Sequence Data; Polyisoprenyl Phosphate Sugars; Protein Processing, Post-Translational; Swainsonine; Viruses | 1991 |
[Inhibitors of alpha-glucosidase].
Topics: 1-Deoxynojirimycin; Acarbose; Blood Glucose; Carbohydrate Metabolism; Clinical Trials as Topic; Diabetes Mellitus; Digestion; Glucosamine; Glycoside Hydrolase Inhibitors; Imino Pyranoses; Insulin; Triglycerides; Trisaccharides | 1991 |
Plagiarizing plants: amino sugars as a class of glycosidase inhibitors.
Topics: 1-Deoxynojirimycin; Amino Sugars; Glucosamine; Glycoside Hydrolases; Imino Pyranoses; Molecular Structure; Plant Physiological Phenomena; Sugar Alcohols | 1990 |
[Inhibitors affecting synthesis and intracellular translocation of glycoproteins as probes].
Topics: 1-Deoxynojirimycin; Aclarubicin; Animals; Anthracyclines; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Bacitracin; Biological Transport; Glucosamine; Glycoproteins; Lipopeptides; Lysosomes; Monensin; Naphthacenes; Oligopeptides; Showdomycin; Tunicamycin | 1985 |
Inhibitors of oligosaccharide processing.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Biological Transport; Carbohydrate Conformation; Cyclohexenes; Glucosamine; Glucosidases; Glucosyltransferases; Indolizines; Inositol; Intracellular Fluid; Mannosidases; Models, Chemical; Oligosaccharides; Polysaccharides; Swainsonine | 1985 |
Inhibitors of the biosynthesis and processing of N-linked oligosaccharides.
Topics: 1-Deoxynojirimycin; Acetylglucosamine; Alkaloids; Animals; Anti-Bacterial Agents; Asparagine; Bacitracin; Biological Transport; Carbohydrate Conformation; Cyclohexenes; Dolichol Phosphates; Glucosamine; Glucose; Glycoproteins; Hydroxycholesterols; Indolizines; Inositol; Lipopeptides; Lovastatin; Mannose; Naphthalenes; Oligopeptides; Oligosaccharides; Peptides; Peptides, Cyclic; Phospholipids; Polyisoprenyl Phosphate Monosaccharides; Pyrimidine Nucleosides; Showdomycin; Structure-Activity Relationship; Swainsonine; Tunicamycin; Uracil | 1984 |
An evaluation of the potential side-effects of alpha-glucosidase inhibitors used for the management of diabetes mellitus.
Topics: 1-Deoxynojirimycin; Acarbose; Administration, Oral; Animals; Blood Glucose; Carbohydrate Sequence; Contraindications; Diabetes Mellitus; Diabetic Nephropathies; Glucosamine; Glycogen; Glycogen Storage Disease; Glycoproteins; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Molecular Sequence Data; Sucrase-Isomaltase Complex; Trisaccharides | 1994 |
Pharmacology of alpha-glucosidase inhibition.
Topics: 1-Deoxynojirimycin; Acarbose; Animals; Blood Glucose; Carbohydrate Sequence; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diabetic Neuropathies; Dietary Carbohydrates; Digestion; Glucosamine; Glycation End Products, Advanced; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Insulin; Molecular Sequence Data; Trisaccharides | 1994 |
Alpha-glucosidase inhibition as an adjunct to the treatment of type 1 diabetes.
Topics: 1-Deoxynojirimycin; Acarbose; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemia; Imino Pyranoses; Trisaccharides | 1993 |
Potential of alpha-glucosidase inhibitors in elderly patients with diabetes mellitus and impaired glucose tolerance.
Topics: 1-Deoxynojirimycin; Acarbose; Aged; Body Weight; Cognition; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucosamine; Glucose Intolerance; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Trisaccharides | 1998 |
Type 2 diabetes: glycemic targets and oral therapies for older patients.
Topics: 1-Deoxynojirimycin; Acarbose; Age Factors; Aged; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Glucosamine; Humans; Hypoglycemic Agents; Imino Pyranoses; Metformin; Piperidines; Sulfonylurea Compounds; Trisaccharides | 1998 |
Drug therapy of postprandial hyperglycaemia.
Topics: 1-Deoxynojirimycin; Acarbose; Amyloid; Carbamates; Diabetes Mellitus; Enzyme Inhibitors; Glucosamine; Glyburide; Humans; Hyperglycemia; Hypoglycemic Agents; Imino Pyranoses; Inositol; Insulin; Insulin Lispro; Islet Amyloid Polypeptide; Piperidines; Postprandial Period; Trisaccharides | 1999 |
[Current status of the treatment of type 2 diabetes mellitus. Alpha-glucosidase inhibitors].
Topics: 1-Deoxynojirimycin; Acarbose; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Disaccharides; Drug Combinations; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hydrolysis; Hypoglycemic Agents; Imino Pyranoses; Insulin; Polysaccharides | 1999 |
Oral pharmacologic management of type 2 diabetes.
Topics: 1-Deoxynojirimycin; Acarbose; Administration, Oral; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Metformin; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; United States | 1999 |
Miglitol: a review of its therapeutic potential in type 2 diabetes mellitus.
Topics: 1-Deoxynojirimycin; Biological Availability; Blood Glucose; Diabetes Mellitus, Type 2; Drug Administration Schedule; Glucosamine; Glucosidases; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Imino Pyranoses; Intestinal Absorption; Liver; Postprandial Period; Randomized Controlled Trials as Topic; Tissue Distribution | 2000 |
Improving management of type 2 diabetes mellitus: 1. alpha-Glucosidase inhibitors.
Topics: 1-Deoxynojirimycin; Acarbose; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemia; Imino Pyranoses | 1999 |
Miglitol: assessment of its role in the treatment of patients with diabetes mellitus.
Topics: 1-Deoxynojirimycin; Aged; Animals; Diabetes Mellitus; Drug Administration Schedule; Drug Interactions; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Intestinal Absorption; Middle Aged; Randomized Controlled Trials as Topic | 2000 |
Miglitol, a new alpha-glucosidase inhibitor.
Topics: 1-Deoxynojirimycin; Animals; Clinical Trials as Topic; Diabetes Mellitus; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses | 1999 |
[Reducing postprandial glucose levels. Glucosidase antagonists].
Topics: 1-Deoxynojirimycin; Acarbose; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucosamine; Glucosidases; Humans; Hypoglycemic Agents; Imino Pyranoses; Postprandial Period | 2002 |
Therapeutic applications of sugar-mimicking glycosidase inhibitors.
Topics: 1-Deoxynojirimycin; alpha-Galactosidase; alpha-Mannosidase; Animals; Carbohydrate Sequence; Disaccharides; Drug Design; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolases; Humans; Mannosidases; Models, Molecular; Molecular Sequence Data; Oligosaccharides; Structure-Activity Relationship | 2001 |
Biochemistry and biotechnological applications of Gluconobacter strains.
Topics: 1-Deoxynojirimycin; Acetic Acid; Ascorbic Acid; Biotechnology; Carbohydrate Metabolism; Genome, Bacterial; Gluconates; Gluconobacter; Glucosamine; Hydrogen-Ion Concentration; Imino Pyranoses | 2002 |
Therapeutic options for the management of type 2 diabetes mellitus.
Topics: 1-Deoxynojirimycin; Adult; Diabetes Mellitus, Type 2; Disease Management; Education, Medical, Continuing; Education, Pharmacy, Continuing; Glucosamine; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Insulin Aspart; Managed Care Programs; Metformin; Thiazoles; Thiazolidinediones; United States | 2002 |
gem-Diamine 1-N-iminosugars and related iminosugars, candidate of therapeutic agents for tumor metastasis.
Topics: 1-Deoxynojirimycin; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Glucosamine; Humans; Monosaccharides; Neoplasm Metastasis | 2003 |
Is there a role for alpha-glucosidase inhibitors in the prevention of type 2 diabetes mellitus?
Topics: 1-Deoxynojirimycin; Acarbose; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Inositol; Randomized Controlled Trials as Topic | 2003 |
[Continuation 50. Type 2 diabetes: possibilities and limitations of pharmacological therapy].
Topics: 1-Deoxynojirimycin; Acarbose; Aged; Blood Glucose; Carbamates; Contraindications; Cyclohexanes; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Inhibitors; Fasting; Follow-Up Studies; Germany; Glucosamine; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemia; Hypoglycemic Agents; Imino Pyranoses; Insulin; Metformin; Middle Aged; Nateglinide; Obesity; Patient Compliance; Phenylalanine; Pioglitazone; Piperidines; Practice Guidelines as Topic; Risk Factors; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones; Time Factors | 2003 |
Alpha-glucosidase inhibitors for type 2 diabetes mellitus.
Topics: 1-Deoxynojirimycin; Acarbose; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Inositol; Randomized Controlled Trials as Topic | 2005 |
[Is it possible to treat the brain? Recent advances in inherited neurodegenerative disorders].
Topics: 1-Deoxynojirimycin; Bone Marrow Transplantation; Cell- and Tissue-Based Therapy; Enzyme Inhibitors; Enzyme Therapy; Genetic Therapy; Glucosamine; Heredodegenerative Disorders, Nervous System; Humans; Stem Cell Transplantation | 2007 |
[Recent therapeutics for Fabry disease].
Topics: 1-Deoxynojirimycin; alpha-Galactosidase; Cell- and Tissue-Based Therapy; Fabry Disease; Genetic Therapy; Glucosamine; Humans; Isoenzymes; Mass Screening; Trihexosylceramides | 2009 |
50 trial(s) available for 1-deoxynojirimycin and glucosamine
| Article | Year |
|---|---|
Effects of alpha-glucosidase inhibitors on mouth to caecum transit time in humans.
Topics: 1-Deoxynojirimycin; Acarbose; Adolescent; Adult; Breath Tests; Gastrointestinal Transit; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hydrogen; Imino Pyranoses; Male; Stimulation, Chemical; Time Factors; Trisaccharides | 1992 |
alpha-Glucosidase inhibition by miglitol in NIDDM patients.
Topics: 1-Deoxynojirimycin; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diet, Diabetic; Dietary Carbohydrates; Fatty Acids, Nonesterified; Female; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Male; Middle Aged | 1992 |
[Delayed absorption of carbohydrates in the therapy of Type II diabetes: comparison between dietary (Muesli) and pharmacological (Alpha-glucosidase inhibition) modification].
Topics: 1-Deoxynojirimycin; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diet, Diabetic; Dietary Carbohydrates; Dietary Fiber; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Intestinal Absorption; Middle Aged | 1991 |
Inhibition of glycemic and hormonal responses after repetitive sucrose and starch loads by different doses of the alpha-glucosidase inhibitor miglitol (BAY m 1099) in man.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Dietary Carbohydrates; Double-Blind Method; Gastric Inhibitory Polypeptide; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Male; Starch; Sucrose | 1991 |
Inhibition of sucrose- and starch-induced glycaemic and hormonal responses by the alpha-glucosidase inhibitor emiglitate (BAY o 1248) in healthy volunteers.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Breath Tests; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Gastric Inhibitory Polypeptide; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hydrogen; Insulin; Male; Starch; Sucrose | 1991 |
Post-prandial glycaemic reduction by an alpha-glucosidase inhibitor in type 2 diabetic patients with therapeutically attained basal normoglycaemia.
Topics: 1-Deoxynojirimycin; Biomarkers; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diet, Diabetic; Eating; Female; Fructosamine; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Hexosamines; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Insulin, Long-Acting; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Reference Values; Time Factors; Triglycerides | 1991 |
Effects of alpha-glucosidase inhibition and viscous fibre on diabetic control and postprandial gut hormone responses.
Topics: 1-Deoxynojirimycin; Adult; Aged; Biomarkers; Blood Glucose; Cholesterol; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dietary Fiber; Double-Blind Method; Eating; Female; Fructosamine; Galactans; Glucosamine; Glycoside Hydrolase Inhibitors; Hexosamines; Humans; Imino Pyranoses; Male; Mannans; Middle Aged; Plant Gums; Random Allocation; Triglycerides | 1990 |
The acute effects of glucosidase inhibition on post-meal glucose increments in insulin-dependent diabetics.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Male; Middle Aged; Randomized Controlled Trials as Topic; Time Factors | 1990 |
The effect of miglitol and acarbose after an oral glucose load: a novel hypoglycaemic mechanism?
Topics: 1-Deoxynojirimycin; Acarbose; Administration, Oral; Adult; Blood Glucose; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Male; Trisaccharides | 1990 |
The effect of short chain fatty acid supplementation on membrane electrolyte transport and blood pressure.
Topics: 1-Deoxynojirimycin; Adult; Biological Transport; Blood Pressure; Double-Blind Method; Electrolytes; Erythrocyte Membrane; Erythrocytes; Fatty Acids, Volatile; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Linoleic Acid; Linoleic Acids; Male; Oleic Acid; Oleic Acids; Palmitic Acids; Potassium; Sodium | 1990 |
Postprandial glycemic control, hormonal effects and carbohydrate malabsorption during long-term administration of the alpha-glucosidase inhibitor miglitol.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Breath Tests; Dietary Carbohydrates; Double-Blind Method; Gastric Inhibitory Polypeptide; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hydrogen; Imino Pyranoses; Insulin; Malabsorption Syndromes; Male; Time Factors | 1990 |
Effect of alpha-glucosidase inhibition on glucose profiles in insulin dependent diabetes.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 1; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Middle Aged; Triglycerides | 1989 |
Effects of 8-wk alpha-glucosidase inhibition on metabolic control, C-peptide secretion, hepatic glucose output, and peripheral insulin sensitivity in poorly controlled type II diabetic patients.
Topics: 1-Deoxynojirimycin; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Liver; Male; Middle Aged | 1989 |
Reduction of postprandial blood glucose by the alpha-glucosidase inhibitor Miglitol (BAY m 1099) in type II diabetes.
Topics: 1-Deoxynojirimycin; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diet; Dose-Response Relationship, Drug; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Middle Aged; Time Factors | 1989 |
The effect of a 1-deoxynojirimycin derivative on post-prandial blood glucose and insulin levels in healthy black and white volunteers.
Topics: 1-Deoxynojirimycin; Adult; Black People; Blood Glucose; Eating; Glucosamine; Glucosidases; Glycoside Hydrolase Inhibitors; Humans; Insulin; Racial Groups; White People | 1985 |
The clinical efficacy of a second-generation alpha-glucosidase inhibitor in non-insulin-dependent diabetic patients.
Topics: 1-Deoxynojirimycin; Adult; Anti-Bacterial Agents; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Male; Middle Aged; Random Allocation; Sulfonylurea Compounds | 1987 |
Alpha glucosidase inhibition in the treatment of non-insulin-dependent diabetes mellitus.
Topics: 1-Deoxynojirimycin; Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Intestinal Absorption; Middle Aged; Random Allocation | 1988 |
Effects of BAYm 1099, new alpha-glucosidase inhibitor, on acute metabolic responses and metabolic control in NIDDM over 1 mo.
Topics: 1-Deoxynojirimycin; 3-Hydroxybutyric Acid; Alanine; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Eating; Fatty Acids, Nonesterified; Female; Glucosamine; Glycerol; Glycoside Hydrolase Inhibitors; Humans; Hydroxybutyrates; Hypoglycemic Agents; Imino Pyranoses; Insulin; Lactates; Male; Middle Aged; Pyruvates | 1988 |
Intestinal and metabolic responses to an alpha-glucosidase inhibitor in normal volunteers.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Breath Tests; Feces; Female; Gastric Inhibitory Polypeptide; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hydrogen; Imino Pyranoses; Insulin; Intestinal Mucosa; Intestines; Male | 1988 |
Effects of prolonged administration of two new alpha-glucosidase inhibitors on blood glucose control, insulin requirements and breath hydrogen excretion in patients with insulin-dependent diabetes mellitus.
Topics: 1-Deoxynojirimycin; Adult; Anti-Bacterial Agents; Blood Glucose; Breath Tests; Diabetes Mellitus, Type 1; Drug Administration Schedule; Glucosamine; Humans; Hydrogen; Imino Pyranoses; Insulin; Male | 1988 |
Effect of two new alpha-glucosidase inhibitors in insulin-dependent diabetic patients.
Topics: 1-Deoxynojirimycin; Adult; Diabetes Mellitus, Type 1; Diet; Double-Blind Method; Female; Glucosamine; Glucosidases; Humans; Hyperglycemia; Hypoglycemia; Imino Pyranoses; Insulin; Male; Random Allocation | 1988 |
A new alpha-glucosidase inhibitor (Bay-m-1099) reduces insulin requirements with meals in insulin-dependent diabetes mellitus.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Eating; Female; Glucosamine; Humans; Imino Pyranoses; Insulin; Male; Random Allocation | 1987 |
Assessment of the clinical efficacy and tolerance of two new alpha-glucosidase inhibitors in insulin-treated diabetics.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Body Weight; Diabetes Mellitus; Drug Tolerance; Fatty Acids, Nonesterified; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Male; Middle Aged | 1987 |
The effect of two new alpha-glucosidase inhibitors on metabolic responses to a mixed meal in normal volunteers.
Topics: 1-Deoxynojirimycin; Adult; Anti-Bacterial Agents; Blood Glucose; Female; Food; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Male; Triglycerides | 1987 |
The effect of new alpha-glucosidase inhibitors (BAY m 1099 and BAY o 1248) on meal-stimulated increases in glucose and insulin levels in man.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Clinical Trials as Topic; Dose-Response Relationship, Drug; Glucosamine; Glucosidases; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Male; Middle Aged; Random Allocation | 1986 |
Effect of alpha-glycohydrolase inhibitors (Bay m1099 and Bay o1248) on sucrose metabolism in normal men.
Topics: 1-Deoxynojirimycin; Administration, Oral; Adult; Blood Glucose; Breath Tests; Fatty Acids, Nonesterified; Glucosamine; Humans; Hydrogen; Imino Pyranoses; Insulin; Lipids; Male; Pulmonary Gas Exchange; Sucrose | 1986 |
Effects of two new alpha-glucosidase inhibitors on glycemic control in patients with insulin-dependent diabetes mellitus.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Breath Tests; Clinical Trials as Topic; Deuterium; Diabetes Mellitus, Type 1; Double-Blind Method; Glucosamine; Humans; Imino Pyranoses; Insulin; Insulin Infusion Systems; Male; Random Allocation | 1986 |
Effects of the alpha-glucosidase inhibitor 1 desoxynojirimycin (Bay m 1099) on postprandial blood glucose, serum insulin and C-peptide levels in type II diabetic patients.
Topics: 1-Deoxynojirimycin; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Eating; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Male; Middle Aged; Obesity; Pancreatic Hormones | 1986 |
A double-blind study on the efficacy and tolerance of a new alpha-glucosidase inhibitor in type-2 diabetics.
Topics: 1-Deoxynojirimycin; Adult; Aged; Anti-Bacterial Agents; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Tolerance; Female; Glucosamine; Humans; Imino Pyranoses; Male; Middle Aged; Random Allocation | 1986 |
Smoothing effect of a new alpha-glucosidase inhibitor BAY m 1099 on blood glucose profiles of sulfonylurea-treated type II diabetic patients.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Male; Middle Aged; Sulfonylurea Compounds | 1986 |
[Miglitol in the treatment of the insulin-dependent diabetic patient. Improved metabolic control and excellent tolerance].
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Glucosamine; Glycated Hemoglobin; Humans; Imino Pyranoses | 1987 |
Comparison of miglitol and glibenclamide in diet-treated type 2 diabetic patients.
Topics: 1-Deoxynojirimycin; Blood Glucose; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Diet, Diabetic; Double-Blind Method; Enzyme Inhibitors; Female; Glucosamine; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Male; Middle Aged; Multivariate Analysis; Time Factors; Treatment Failure; Triglycerides | 1995 |
Effect of miglitol (BAY m-1099) on fasting blood glucose in type 2 diabetes mellitus.
Topics: 1-Deoxynojirimycin; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Fasting; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Male; Middle Aged | 1994 |
Effects of the carbohydrase inhibitor miglitol in sulfonylurea-treated NIDDM patients.
Topics: 1-Deoxynojirimycin; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Lipids; Male; Middle Aged; Time Factors | 1994 |
Does suppression of postprandial blood glucose excursions by the alpha-glucosidase inhibitor miglitol improve insulin sensitivity in diet-treated type II diabetic patients?
Topics: 1-Deoxynojirimycin; Biomarkers; Blood Glucose; Cholesterol; Combined Modality Therapy; Diabetes Mellitus, Type 2; Diet, Diabetic; Double-Blind Method; Enzyme Inhibitors; Female; Fructosamine; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Male; Metabolic Clearance Rate; Middle Aged; Triglycerides | 1996 |
Study of the effect of miglitol on the pharmacokinetics and pharmacodynamics of warfarin in healthy males.
Topics: 1-Deoxynojirimycin; Adult; Anticoagulants; Blood Coagulation; Cross-Over Studies; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Glucosamine; Glucosidases; Humans; Imino Pyranoses; Male; Stereoisomerism; Warfarin | 1996 |
Miglitol (Bay m 1099) has no extraintestinal effects on glucose control in healthy volunteers.
Topics: 1-Deoxynojirimycin; Adult; Area Under Curve; Blood Glucose; C-Peptide; Double-Blind Method; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Intestine, Small; Male; Placebos | 1996 |
The efficacy and safety of miglitol therapy compared with glibenclamide in patients with NIDDM inadequately controlled by diet alone.
Topics: 1-Deoxynojirimycin; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diarrhea; Diet, Diabetic; Double-Blind Method; Enzyme Inhibitors; Fasting; Female; Flatulence; Glucosamine; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemia; Hypoglycemic Agents; Imino Pyranoses; Male; Middle Aged; Placebos; Postprandial Period | 1997 |
Pharmacokinetics of miglitol. Absorption, distribution, metabolism, and excretion following administration to rats, dogs, and man.
Topics: 1-Deoxynojirimycin; Administration, Oral; Animals; Autoradiography; Blood Proteins; Dogs; Duodenum; Enzyme Inhibitors; Feces; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Injections, Intravenous; Male; Milk; Placenta; Pregnancy; Protein Binding; Rats; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Tissue Distribution | 1997 |
Long-term titrated-dose alpha-glucosidase inhibition in non-insulin-requiring Hispanic NIDDM patients.
Topics: 1-Deoxynojirimycin; Albuminuria; Blood Glucose; Creatinine; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Enzyme Inhibitors; Female; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Hispanic or Latino; Humans; Imino Pyranoses; Insulin; Lipids; Male; Middle Aged; Placebos; Postprandial Period; Time Factors; Treatment Outcome | 1998 |
Chronic treatment of African-American type 2 diabetic patients with alpha-glucosidase inhibition.
Topics: 1-Deoxynojirimycin; Black People; Blood Glucose; Cholesterol, LDL; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Enzyme Inhibitors; Female; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Male; Middle Aged; Placebos; Postprandial Period; Single-Blind Method; Sulfonylurea Compounds; Treatment Outcome; Triglycerides | 1998 |
Advantages of alpha-glucosidase inhibition as monotherapy in elderly type 2 diabetic patients.
Topics: 1-Deoxynojirimycin; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Enzyme Inhibitors; Fasting; Female; Food; Glucosamine; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Kinetics; Male | 1998 |
Long-term effectiveness of a new alpha-glucosidase inhibitor (BAY m1099-miglitol) in insulin-treated type 2 diabetes mellitus.
Topics: 1-Deoxynojirimycin; Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Enzyme Inhibitors; Fasting; Female; Follow-Up Studies; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Male; Middle Aged; Postprandial Period; Time Factors | 1998 |
[Alpha-glucosidase inhibitor for type 2 diabetic patients. Clinical study with miglitol].
Topics: 1-Deoxynojirimycin; Diabetes Mellitus, Type 2; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin Resistance | 2000 |
Improved glycaemic control with miglitol in inadequately-controlled type 2 diabetics.
Topics: 1-Deoxynojirimycin; Analysis of Variance; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 2; Diet, Diabetic; Double-Blind Method; Drug Therapy, Combination; Female; Glucosamine; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Imino Pyranoses; Male; Metformin; Middle Aged; Placebos | 2001 |
The synergistic effect of miglitol plus metformin combination therapy in the treatment of type 2 diabetes.
Topics: 1-Deoxynojirimycin; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Fasting; Female; Glucosamine; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Male; Metformin; Middle Aged; Placebos; Postprandial Period; Racial Groups | 2001 |
Miglitol combined with metformin improves glycaemic control in type 2 diabetes.
Topics: 1-Deoxynojirimycin; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Glucosamine; Humans; Hypoglycemic Agents; Imino Pyranoses; Male; Metformin; Middle Aged; Single-Blind Method | 2001 |
Dose-dependent efficacy of miglitol, an alpha-glucosidase inhibitor, in type 2 diabetic patients on diet alone: results of a 24-week double-blind placebo-controlled study.
Topics: 1-Deoxynojirimycin; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Female; Food; Gastrointestinal Diseases; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Male; Middle Aged; Placebos | 2002 |
The effects of miglitol on glucagon-like peptide-1 secretion and appetite sensations in obese type 2 diabetics.
Topics: 1-Deoxynojirimycin; Adult; Aged; Appetite; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucosamine; Humans; Hypoglycemic Agents; Imino Pyranoses; Middle Aged; Obesity; Peptide Fragments; Postprandial Period; Protein Precursors | 2002 |
HbA(1c) and glycemic profile, basal- and post-treatment with Miglitol, in an area with a Mediterranean diet.
Topics: 1-Deoxynojirimycin; Blood Glucose; Diabetes Mellitus, Type 2; Diet; Diet, Diabetic; Fasting; Glucosamine; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Mediterranean Region; Postprandial Period; Regression Analysis | 2002 |
321 other study(ies) available for 1-deoxynojirimycin and glucosamine
| Article | Year |
|---|---|
Purification and properties of an induced beta-D-glucosidase from stachybotrys atra.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; beta-Glucosidase; Dithionitrobenzoic Acid; Enzyme Induction; Gluconates; Glucosamine; Glucosidases; Hexoses; Hydrogen-Ion Concentration; Kinetics; Mitosporic Fungi; Molecular Weight; Stachybotrys; Stereoisomerism; Substrate Specificity; Temperature | 1978 |
Affinity of glucose analogs for alpha-glucan phosphorylases from rabbit muscle and potato tubers.
Topics: 1-Deoxynojirimycin; Adenosine Monophosphate; Animals; Fluorides; Glucosamine; Glucose; Glucosephosphates; Isomerism; Kinetics; Molecular Conformation; Muscles; Phosphorylases; Plants; Rabbits; Structure-Activity Relationship | 1977 |
Synthesis of (+)- and (-)-nojirimycin and their 1-deoxy derivatives from myo-inositol.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; beta-Galactosidase; beta-Glucosidase; Glucosamine; Glycoside Hydrolases; Inositol; Stereoisomerism; Sucrase | 1992 |
Nonselective utilization of the endomannosidase pathway for processing glycoproteins by human hepatoma (HepG2) cells.
Topics: 1-Deoxynojirimycin; Carcinoma, Hepatocellular; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Glucosamine; Glycoproteins; Glycoside Hydrolases; Hexosaminidases; Humans; Liver Neoplasms; Mannosidases; Precipitin Tests; Tumor Cells, Cultured | 1992 |
Effect of lengthening lymphocyte function-associated antigen 3 on adhesion to CD2.
Topics: 1-Deoxynojirimycin; Animals; Antigens, Differentiation, T-Lymphocyte; Carbohydrate Metabolism; Carbohydrates; CD2 Antigens; Cell Adhesion Molecules; CHO Cells; Cricetinae; Glucosamine; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Neuraminidase; Receptors, Immunologic; Recombinant Fusion Proteins; Structure-Activity Relationship | 1992 |
Inhibitors of glycoprotein processing act at an early stage of myogenesis.
Topics: 1-Deoxynojirimycin; Actins; Animals; Blotting, Northern; Blotting, Western; Cell Line; Cyclohexenes; DNA Probes; Glucosamine; Glycoproteins; Glycoside Hydrolases; Inositol; Mice; Muscle Proteins; Muscles; MyoD Protein; Myogenin; Rats; RNA | 1992 |
Transcriptional and post-translational regulation of beta 1 integrin expression during keratinocyte terminal differentiation.
Topics: 1-Deoxynojirimycin; Antibodies; Blotting, Northern; Cell Differentiation; Cells, Cultured; Down-Regulation; Electrophoresis, Gel, Pulsed-Field; Fibronectins; Glucosamine; Glycosylation; Humans; Integrins; Keratinocytes; Kinetics; Plasmids; Protein Processing, Post-Translational; Receptors, Fibronectin; Receptors, Immunologic; RNA; Transcription, Genetic | 1992 |
Synthesis of 1-deoxynojirimycin-containing glycans related to the Lewis X and sialyl-Lewis X epitopes recognized by LEC-CAMs.
Topics: 1-Deoxynojirimycin; Carbohydrate Sequence; Cell Adhesion Molecules; Epitopes; Glucosamine; Glucosidases; Lewis X Antigen; Molecular Sequence Data; Polysaccharides | 1992 |
Molecular modelling of acarviosine, the pseudo-disaccharide moiety of acarbose, and other inhibitors of alpha-amylases.
Topics: 1-Deoxynojirimycin; alpha-Amylases; Amino Sugars; Carbohydrate Sequence; Glucosamine; Isomerism; Maltose; Mathematical Computing; Molecular Sequence Data | 1992 |
Modulation of cell-surface transferrin receptor by the imino sugar N-butyldeoxynojirimycin.
Topics: 1-Deoxynojirimycin; Antiviral Agents; Cell Line; Cell Membrane; Glucosamine; Glycoside Hydrolases; HIV; Humans; Kinetics; Receptors, Transferrin; Transferrin | 1992 |
Location of the two catalytic sites in intestinal lactase-phlorizin hydrolase. Comparison with sucrase-isomaltase and with other glycosidases, the membrane anchor of lactase-phlorizin hydrolase.
Topics: 1-Deoxynojirimycin; Amino Acid Sequence; Animals; beta-Galactosidase; Binding Sites; Catalysis; DNA; Glucosamine; Glycoside Hydrolases; Inositol; Intestines; Lactase; Lactase-Phlorizin Hydrolase; Microvilli; Molecular Sequence Data; Oligo-1,6-Glucosidase; Rabbits; Sequence Homology, Nucleic Acid; Sucrase | 1992 |
Activation of lipoprotein lipase in cardiac myocytes by glycosylation requires trimming of glucose residues in the endoplasmic reticulum.
Topics: 1-Deoxynojirimycin; Animals; Cycloheximide; Endoplasmic Reticulum; Enzyme Activation; Glucosamine; Glucose; Glucosidases; Glycosylation; Indolizines; Kinetics; Lipoprotein Lipase; Male; Myocardium; Rats; Rats, Inbred Strains | 1992 |
Soluble aggregates of the human PiZ alpha 1-antitrypsin variant are degraded within the endoplasmic reticulum by a mechanism sensitive to inhibitors of protein synthesis.
Topics: 1-Deoxynojirimycin; 2,4-Dinitrophenol; alpha 1-Antitrypsin; Animals; Brefeldin A; Cycloheximide; Cyclopentanes; Dinitrophenols; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Glucosamine; Golgi Apparatus; Humans; Liver Neoplasms, Experimental; Mice; Nocodazole; Protein Synthesis Inhibitors; Puromycin; Transfection; Tumor Cells, Cultured | 1992 |
Human T-cell leukemia virus type I envelope protein maturation process: requirements for syncytium formation.
Topics: 1-Deoxynojirimycin; Animals; Cell Line; Giant Cells; Glucosamine; Glycoside Hydrolases; Glycosylation; Human T-lymphotropic virus 1; Monensin; Mutagenesis, Site-Directed; Plasmids; Promoter Regions, Genetic; Protein Processing, Post-Translational; Swainsonine; Transfection; Tunicamycin; Viral Envelope Proteins | 1992 |
Human cathepsin D precursor is associated with a 60 kDa glycosylated polypeptide.
Topics: 1-Deoxynojirimycin; Brefeldin A; Calcitriol; Cathepsin D; Cell Line; Cross-Linking Reagents; Cyclopentanes; Enzyme Precursors; Glucosamine; Glycoside Hydrolases; Glycosylation; Humans; Molecular Weight; Protein Processing, Post-Translational | 1992 |
Rapid and reversible inhibition of tyrosinase activity by glucosidase inhibitors in human melanoma cells.
Topics: 1-Deoxynojirimycin; Antibodies, Monoclonal; Antigens; Blotting, Western; Cell Survival; Chromatography, Affinity; Flow Cytometry; Glucosamine; Glucosidases; Humans; Indolizines; Melanocytes; Melanoma, Experimental; Methionine; Monophenol Monooxygenase; Skin Neoplasms; Subcellular Fractions; Sulfur Radioisotopes; Tumor Cells, Cultured | 1992 |
Characterization of the endomannosidase pathway for the processing of N-linked oligosaccharides in glucosidase II-deficient and parent mouse lymphoma cells.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Glucosidases; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glucosamine; Glucose; Glycopeptides; Glycoside Hydrolase Inhibitors; Hexosaminidases; Lymphoma; Mannosidases; Mice; Oligosaccharides; Tumor Cells, Cultured | 1992 |
Effect of inhibitors of N-linked oligosaccharide processing on the high-affinity transport of D-aspartate by C6 glioma cells.
Topics: 1-Deoxynojirimycin; Aspartic Acid; Biological Transport; Glioma; Glucosamine; Glucosidases; Glycosylation; Indolizines; Tumor Cells, Cultured | 1992 |
3-Hydroxy-3-methylglutaryl-coenzyme A reductase and T cell receptor alpha subunit are differentially degraded in the endoplasmic reticulum.
Topics: 1-Deoxynojirimycin; Acyl Coenzyme A; Animals; Brefeldin A; CHO Cells; Cricetinae; Cycloheximide; Cyclopentanes; Diamide; Endoplasmic Reticulum; Glucosamine; Plasmids; Protease Inhibitors; Receptors, Antigen, T-Cell, alpha-beta; Transfection | 1992 |
Genetic toxicology studies of an anti-AIDS drug.
Topics: 1-Deoxynojirimycin; Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Bone Marrow; CHO Cells; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; Female; Glucosamine; Hypoxanthine Phosphoribosyltransferase; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Salmonella | 1992 |
Evidence for processing of dolichol-linked oligosaccharides in patients with neuronal ceroid-lipofuscinosis.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Carbohydrate Sequence; Cells, Cultured; Chromatography, High Pressure Liquid; Dolichol Phosphates; Glucosamine; Humans; Molecular Sequence Data; Neuronal Ceroid-Lipofuscinoses; Oligosaccharides; Polyisoprenyl Phosphate Oligosaccharides | 1992 |
Role of asparagine-linked carbohydrates in pulmonary metastasis of B16-F10 murine melanoma cells: implication through glycosylation inhibition by nojirimycin.
Topics: 1-Deoxynojirimycin; Animals; Glucosamine; Glycosylation; Killer Cells, Natural; Lectins; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oligosaccharides | 1992 |
Chemical modification of the glucosidase inhibitor 1-deoxynojirimycin. Structure-activity relationships.
Topics: 1-Deoxynojirimycin; Alkylation; alpha 1-Antitrypsin; Carcinoma, Hepatocellular; Chromatography, Gel; Endoplasmic Reticulum; Glucosamine; Glucosidases; Kinetics; Liver Neoplasms; Molecular Conformation; Structure-Activity Relationship; Tumor Cells, Cultured | 1991 |
6-0-butanoylcastanospermine (MDL 28,574) inhibits glycoprotein processing and the growth of HIVs.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Cell Line; Cell Line, Transformed; Dose-Response Relationship, Drug; Gene Products, env; Glucosamine; Glycoside Hydrolase Inhibitors; HIV Envelope Protein gp120; HIV Envelope Protein gp160; HIV-1; Humans; Indolizines; Mice; Moloney murine leukemia virus; Protein Precursors; Viral Plaque Assay; Zalcitabine | 1991 |
Effect of inhibiting N-glycosylation or oligosaccharide processing on vasoactive intestinal peptide receptor binding activity and structure.
Topics: 1-Deoxynojirimycin; Alkaloids; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Glucosamine; Glycosylation; Humans; Indolizines; Mannose; Methionine; Molecular Weight; Oligosaccharides; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Structure-Activity Relationship; Swainsonine; Tumor Cells, Cultured; Tunicamycin; Vasoactive Intestinal Peptide | 1991 |
A novel glycosylation phenotype expressed by Lec23, a Chinese hamster ovary mutant deficient in alpha-glucosidase I.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Carbohydrate Metabolism; Carbohydrate Sequence; CHO Cells; Chromatography, Affinity; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Concanavalin A; Cricetinae; Glucosamine; Glucose; Glycosylation; Kinetics; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Molecular Sequence Data; Mutation; Phenotype; Protein Processing, Post-Translational; Vesicular stomatitis Indiana virus; Viral Envelope Proteins | 1991 |
Carbohydrate synthesis inhibitors decrease interleukin 1-stimulated lymphocyte binding to endothelial cells.
Topics: 1-Deoxynojirimycin; Alkaloids; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Glucosamine; Glycoconjugates; Glycoside Hydrolases; Glycosylation; Humans; In Vitro Techniques; Indolizines; Interleukin-1; Lymphocyte Function-Associated Antigen-1; Lymphocytes; Mannosidases; Protein Processing, Post-Translational; Receptors, Leukocyte-Adhesion; Receptors, Lymphocyte Homing; Swainsonine | 1991 |
The effects of low-dose Bay-m-1099 (Miglitol) on serum lipids and liver enzyme activity of obese and obese-diabetic corpulent rats.
Topics: 1-Deoxynojirimycin; Adipose Tissue; Animals; Blood Glucose; Blood Proteins; Diabetes Mellitus; Glucokinase; Glucosamine; Glucosephosphate Dehydrogenase; Glycoside Hydrolase Inhibitors; Imino Pyranoses; Insulin; Lipids; Liver; Obesity; Phenotype; Rats; Weight Gain | 1991 |
Effect of a glucosidase inhibitor on the bioactivity and immunoreactivity of human immunodeficiency virus type 1 envelope glycoprotein.
Topics: 1-Deoxynojirimycin; Animals; Blotting, Western; Carbohydrate Sequence; Carbohydrates; CD4-Positive T-Lymphocytes; Cell Line; Enzyme-Linked Immunosorbent Assay; Gene Products, env; Glucosamine; Glucosidases; Glycosylation; HIV Envelope Protein gp120; HIV Envelope Protein gp160; HIV-1; Humans; Molecular Sequence Data; Protein Precursors; Tumor Cells, Cultured | 1991 |
The significance of carbohydrate trimming for the antigenicity of the Semliki Forest virus glycoprotein E2.
Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; Aedes; Animals; Antibodies, Monoclonal; Antigens, Viral; Antiviral Agents; Binding, Competitive; Blotting, Western; Carbohydrate Sequence; Cells, Cultured; Chick Embryo; Enzyme-Linked Immunosorbent Assay; Epitopes; Fibroblasts; Glucosamine; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mercaptoethanol; Molecular Sequence Data; Neutralization Tests; Oligosaccharides; Peptides; Semliki forest virus; Viral Proteins | 1990 |
Inhibition of HIV and SIV infectivity by blockade of alpha-glucosidase activity.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Glucosamine; Glycoside Hydrolase Inhibitors; HIV; Humans; Kinetics; Models, Biological; Oligosaccharides; Recombination, Genetic; RNA-Directed DNA Polymerase; Simian Immunodeficiency Virus; Vaccinia virus; Viral Envelope Proteins; Viral Plaque Assay; Virus Replication | 1991 |
Effects of inhibitors of oligosaccharide processing on P0 protein synthesis and incorporation into PNS myelin.
Topics: 1-Deoxynojirimycin; Alkaloids; Amino Acids; Animals; Carbohydrate Sequence; Carbon Radioisotopes; Fucose; Glucosamine; Glycoproteins; Glycoside Hydrolases; Indolizines; Mannose; Molecular Sequence Data; Molecular Weight; Myelin P0 Protein; Myelin Proteins; Myelin Sheath; Oligosaccharides; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; Sciatic Nerve; Swainsonine; Tritium | 1991 |
Lysosomal storage of glycogen as a sequel of alpha-glucosidase inhibition by the absorbed deoxynojirimycin derivative emiglitate (BAYo1248). A drug-induced pattern of hepatic glycogen storage mimicking Pompe's disease (glycogenosis type II).
Topics: 1-Deoxynojirimycin; Acarbose; Animals; Female; Glucosamine; Glycogen Storage Disease Type II; Glycoside Hydrolase Inhibitors; Imino Pyranoses; Liver; Liver Glycogen; Lysosomes; Microscopy, Electron; Rats; Rats, Inbred Strains; Trisaccharides | 1991 |
N-methyl-N-(5-carboxypentyl)-1-deoxynojirimycin, a new affinity ligand for the purification of trimming glucosidase I.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Chromatography, Affinity; Glucosamine; Glycoside Hydrolase Inhibitors; Kinetics; Ligands; Liver; Structure-Activity Relationship; Swine | 1991 |
alpha-Glucosidase II-deficient cells use endo alpha-mannosidase as a bypass route for N-linked oligosaccharide processing.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; alpha-Mannosidase; Animals; Chromatography, Affinity; Chromatography, Paper; Glucosamine; Glycoside Hydrolase Inhibitors; Kinetics; Lymphoma; Mannosidases; Mice; Mutation; Oligosaccharides; Tumor Cells, Cultured | 1991 |
A major proportion of N-glycoproteins are transiently glucosylated in the endoplasmic reticulum.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Endoplasmic Reticulum; Glucosamine; Glucose; Glycoproteins; Hexosaminidases; Indolizines; Mannosidases; Substrate Specificity; Trypanosoma cruzi | 1991 |
Differential effects of glycoprotein processing inhibition on experimental metastasis formation by T24-H-ras transformed fibroblasts.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Cell Line; Cell Transformation, Neoplastic; Genes, ras; Glucosamine; Glycoproteins; Glycoside Hydrolases; Indolizines; Kinetics; Mice; Neoplasm Metastasis; Receptors, Concanavalin A; Swainsonine; Transfection | 1991 |
Glucosylation of glycoproteins in Crithidia fasciculata.
Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; Animals; Carbohydrate Conformation; Carbohydrate Sequence; Crithidia; Electrophoresis, Paper; Glucosamine; Glucose; Glucosidases; Glycoproteins; Glycosylation; Indolizines; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Microsomes; Molecular Sequence Data; Oligosaccharides; Protein Processing, Post-Translational; Protozoan Proteins; Trisaccharides | 1991 |
Removal of N-linked oligosaccharides of presumptive ectoderm impairs neural induction in Pleurodeles waltl.
Topics: 1-Deoxynojirimycin; Alkaloids; Amidohydrolases; Animals; Ectoderm; Glucosamine; Mannosidases; Nervous System; Oligosaccharides; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Pleurodeles; Swainsonine | 1991 |
Glycosylation, activity and secretion of lipoprotein lipase in cultured brown adipocytes of newborn mice. Effect of tunicamycin, monensin, 1-deoxymannojirimycin and swainsonine.
Topics: 1-Deoxynojirimycin; Adipose Tissue, Brown; Alkaloids; Animals; Cell Compartmentation; Cells, Cultured; Cycloheximide; Fluorescent Antibody Technique; Glucosamine; Glycosylation; Heparin; In Vitro Techniques; Lipoprotein Lipase; Mice; Mice, Mutant Strains; Monensin; Protein Processing, Post-Translational; Swainsonine; Tunicamycin | 1991 |
In vitro hydrolysis of oligomannose-type sugar chains by an alpha-1,2-mannosidase from microsomes of developing castor bean cotyledons.
Topics: 1-Deoxynojirimycin; Carbohydrate Sequence; Chromatography, Gel; Edetic Acid; Glucosamine; Hydrolysis; Mannose; Mannosidases; Microsomes; Molecular Sequence Data; Plant Development; Plants | 1991 |
Biosynthesis and intracellular movement of the melanosomal membrane glycoprotein gp75, the human b (brown) locus product.
Topics: 1-Deoxynojirimycin; Alkaloids; Antibodies, Monoclonal; Cell Line; Fucose; Glucosamine; Glycoside Hydrolases; Glycosylation; Humans; Indolizines; Mannose; Melanoma; Membrane Glycoproteins; Methionine; Molecular Weight; Protein Processing, Post-Translational; Swainsonine; Tunicamycin | 1991 |
The N-glycan processing in HT-29 cells is a function of their state of enterocytic differentiation. Evidence for an atypical traffic associated with change in polypeptide stability in undifferentiated HT-29 cells.
Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Biological Transport; Cell Differentiation; Colon; Colonic Neoplasms; Glucosamine; Humans; In Vitro Techniques; Leupeptins; Mannosidases; Membrane Glycoproteins; Monensin; Polysaccharides; Protein Processing, Post-Translational; Tumor Cells, Cultured | 1991 |
Substrate specificity of rat liver cytosolic alpha-D-mannosidase. Novel degradative pathway for oligomannosidic type glycans.
Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Carbohydrate Conformation; Carbohydrate Sequence; Cytosol; Glucosamine; Isomerism; Kinetics; Liver; Lysosomes; Magnetic Resonance Spectroscopy; Mannosidases; Molecular Sequence Data; Oligosaccharides; Rats; Substrate Specificity; Swainsonine | 1991 |
Glycoprotein expression in mouse cerebellum: effects of inhibitors of N-linked glycosylation.
Topics: 1-Deoxynojirimycin; Animals; Cerebellum; Embryo, Mammalian; Glucosamine; Glycoproteins; Glycoside Hydrolases; Glycosylation; Golgi Apparatus; Indolizines; Mice; Organ Culture Techniques; Subcellular Fractions; Swainsonine; Tunicamycin | 1991 |
Oligosaccharides at each glycosylation site make structure-dependent contributions to biological properties of human tissue plasminogen activator.
Topics: 1-Deoxynojirimycin; Fibrin; Glucosamine; Glycoproteins; Glycosylation; Humans; Lysine; Neuraminidase; Oligosaccharides; Substrate Specificity; Tissue Plasminogen Activator | 1991 |
Anti-HIV drug mechanism.
Topics: 1-Deoxynojirimycin; Antiviral Agents; Glucosamine; HIV; HIV Envelope Protein gp120; Protein Conformation | 1991 |
Expression of choline acetyltransferase activity in a co-culture of spinal cord and skeletal muscle cells is inhibited by myogenic differentiation inhibitors.
Topics: 1-Deoxynojirimycin; Animals; Cell Communication; Cell Differentiation; Cells, Cultured; Choline O-Acetyltransferase; Concanavalin A; Creatine Kinase; Embryo, Mammalian; Glucosamine; Kinetics; Mice; Muscles; Spinal Cord | 1991 |
[Inhibitor of carbohydrate metabolism (inhibitor of gluconeogenesis, disaccharidase inhibitor)].
Topics: 1-Deoxynojirimycin; 3-Mercaptopropionic Acid; Acarbose; Animals; Carbohydrate Metabolism; Cyclohexanols; Cycloserine; Disaccharidases; Gluconeogenesis; Glucosamine; Humans; Hydrazines; Imino Pyranoses; Liver; Oleic Acids; Trisaccharides | 1991 |
Effects of alpha-glucosidase inhibition on meal glucose tolerance and timing of insulin administration in patients with type I diabetes mellitus.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Eating; Energy Intake; Glucosamine; Glucose Clamp Technique; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Male | 1991 |
Chemical modification of a beta-glucosidase from Schizophyllum commune: evidence for essential carboxyl groups.
Topics: 1-Deoxynojirimycin; Basidiomycota; beta-Glucosidase; Carbodiimides; Cations, Divalent; Chromatography, Affinity; Glucosamine; Glucosidases; Hydrogen-Ion Concentration; Kinetics; Schizophyllum | 1990 |
Specific N-linked oligosaccharides are required for oligodendroglial differentiation but probably not for astrocytic differentiation.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Astrocytes; Brain; Cell Differentiation; Cells, Cultured; Glucosamine; Glycoproteins; Indolizines; Oligodendroglia; Rats; Rats, Inbred Strains | 1990 |
Biosynthesis and processing of bovine cartilage link proteins.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Cartilage, Articular; Cattle; Cells, Cultured; Extracellular Matrix Proteins; Glucosamine; Glycoside Hydrolases; Glycosylation; Indolizines; Kinetics; Leucine; Oligosaccharides; Protein Biosynthesis; Protein Precursors; Protein Processing, Post-Translational; Proteins; Proteoglycans; Sulfates; Sulfur Radioisotopes; Tritium | 1990 |
Inhibition of alpha-L-fucosidase by derivatives of deoxyfuconojirimycin and deoxymannojirimycin.
Topics: 1-Deoxynojirimycin; alpha-L-Fucosidase; Chemical Phenomena; Chemistry; Glucosamine; Humans; Imino Pyranoses; Liver; Methylation; Sugar Alcohols | 1990 |
Calcium ion activation of rabbit liver alpha 1,2-mannosidase.
Topics: 1-Deoxynojirimycin; Animals; Calcium; Cations, Divalent; Enzyme Activation; Glucosamine; Hydrogen-Ion Concentration; Kinetics; Liver; Mannosidases; Rabbits | 1990 |
Effects of deoxymannojirimycin and castanospermine on the polarized secretion of thyroglobulin.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Chemical Phenomena; Chemistry; Glucosamine; Glucosidases; Indolizines; Mannosidases; Oligosaccharides; Thyroglobulin; Thyroid Gland | 1990 |
Dual effect of 1-deoxymannojirimycin on the mannose uptake and on the N-glycan processing of the human colon cancer cell line HT-29.
Topics: 1-Deoxynojirimycin; Adenocarcinoma; alpha-Mannosidase; Cell Differentiation; Colonic Neoplasms; Glucosamine; Humans; Kinetics; Mannose; Mannosidases; Polysaccharides; Tumor Cells, Cultured | 1990 |
Purification to homogeneity and properties of mannosidase II from mung bean seedlings.
Topics: 1-Deoxynojirimycin; Alkaloids; Arabinose; Cell Membrane; Chromatography, DEAE-Cellulose; Enzyme Stability; Fabaceae; Glucosamine; Hydrogen-Ion Concentration; Imino Furanoses; Mannosidases; Oligosaccharides; Plants, Medicinal; Seeds; Solubility; Substrate Specificity; Sugar Alcohols; Swainsonine | 1990 |
Heterogeneity of the glucose transporter in malignant and suppressed hybrid cells.
Topics: 1-Deoxynojirimycin; Animals; Brain; Cell Line; Erythrocytes; Glucosamine; Glycosylation; Humans; Hybrid Cells; Immune Sera; Immunoblotting; Mannosidases; Mice; Monosaccharide Transport Proteins; Neoplasms; Neoplasms, Experimental; Proteins; Rats; Tumor Cells, Cultured; Tunicamycin | 1990 |
Glycosylation and processing of carbohydrate side chains of ecto-5'-nucleotidase in cultured human chorionic cells.
Topics: 1-Deoxynojirimycin; 5'-Nucleotidase; Alkaloids; Carbohydrate Metabolism; Cells, Cultured; Chorionic Villi; Glucosamine; Glycosylation; Humans; Mannosidases; Swainsonine; Tunicamycin | 1990 |
Effect of glycosylation inhibitors and acidotropic amines on the synthesis, processing, and intracellular-extracellular distribution of alpha-L-fucosidase in B-lymphoblastoid cells.
Topics: 1-Deoxynojirimycin; alpha-L-Fucosidase; Ammonium Chloride; B-Lymphocytes; Cells, Cultured; Chloroquine; Glucosamine; Glucosidases; Glycosylation; Humans; Mannosidases; Monensin; Tunicamycin | 1990 |
Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Anti-Bacterial Agents; Cell Line; Glucosamine; Glycoproteins; Glycoside Hydrolases; Glycosylation; Golgi Apparatus; Indolizines; Kinetics; Lymphocytic choriomeningitis virus; Protein Processing, Post-Translational; Temperature; Tunicamycin | 1990 |
Human acid beta-glucosidase: use of sphingosyl and N-alkyl-glucosylamine inhibitors to investigate the properties of the active site.
Topics: 1-Deoxynojirimycin; Binding Sites; Female; Glucosamine; Glucosidases; Glucosylceramidase; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Pregnancy; Protein Conformation; Sphingosine | 1990 |
Regulation of epidermal growth factor receptor signal transduction. Role of gangliosides.
Topics: 1-Deoxynojirimycin; Amino Acid Sequence; Animals; Carbohydrate Sequence; Cell Line; Cell Membrane; Clone Cells; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Gangliosides; Glucosamine; Humans; Insulin; Kinetics; Molecular Sequence Data; Molecular Weight; Peptides; Phosphorylation; Signal Transduction; Transfection | 1990 |
Effect of glycosylation inhibitors on N-glycosylpeptides and on invasion of malignant mouse MO4 cells in vitro.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Antiviral Agents; Cell Transformation, Viral; Chick Embryo; Glucosamine; Glucosylceramidase; Glycosylation; Imino Furanoses; Indolizines; Mannitol; Mannosidases; Mice; Mice, Inbred C3H; Neoplasm Invasiveness; Peptides; Polysaccharides; Pyrrolidines; Swainsonine; Tumor Cells, Cultured | 1990 |
Glycoproteins of cultured cerebellar explants: effect of inhibitors of N-linked glycosylation.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Cerebellum; Culture Techniques; Glucosamine; Glycoside Hydrolase Inhibitors; Glycosylation; Indolizines; Mannosidases; Membrane Glycoproteins; Mice; Nerve Tissue Proteins; Swainsonine; Tunicamycin | 1990 |
Inhibition of glycoprotein processing blocks assembly of spicules during development of the sea urchin embryo.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Carbohydrate Sequence; Cells, Cultured; Embryo, Nonmammalian; Female; Fertilization; Glucosamine; Glycopeptides; Glycoproteins; Glycoside Hydrolases; Indolizines; Molecular Sequence Data; Oligosaccharides; Protein Processing, Post-Translational; Sea Urchins; Swainsonine | 1990 |
Structure and biosynthesis of the xylose-containing carbohydrate moiety of rice alpha-amylase.
Topics: 1-Deoxynojirimycin; alpha-Amylases; Carbohydrate Sequence; Cells, Cultured; Chromatography, High Pressure Liquid; Glucosamine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligosaccharides; Oryza; Temperature; Tunicamycin; Xylose | 1990 |
Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I.
Topics: 1-Deoxynojirimycin; Actinomycetales; Alkaloids; Animals; Cell Line; Cytosol; Glucosamine; Golgi Apparatus; Kinetics; Liver; Male; Mannose; Mannosidases; Microsomes, Liver; Oligosaccharides; Plants; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains | 1990 |
Easy assembly of ligands for glycosidase affinity chromatography.
Topics: 1-Deoxynojirimycin; Aldehydes; Borohydrides; Chemical Phenomena; Chemistry; Chromatography, Affinity; Cyanides; Glucosamine; Glycoside Hydrolases; Hydrochloric Acid; Hydrogen-Ion Concentration; Hydrolysis; Molecular Structure | 1990 |
Comparative properties of human alpha-1-proteinase inhibitor glycosylation variants.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha 1-Antitrypsin; Carbohydrates; Cell Line; Drug Stability; Glucosamine; Glycosylation; Hot Temperature; Humans; Leukocyte Elastase; Liver; Pancreatic Elastase; Structure-Activity Relationship; Swainsonine; Tunicamycin | 1990 |
EGF stimulates the processing and export of a secreted form of EGF receptor.
Topics: 1-Deoxynojirimycin; Alkaloids; Biological Transport; Cell Line; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation; Glucosamine; Glycosylation; Humans; Kinetics; Molecular Weight; Protein Processing, Post-Translational; RNA, Messenger; Swainsonine; Tunicamycin | 1990 |
Hormonal control of cardiac lipolysis by glyco(geno)lysis.
Topics: 1-Deoxynojirimycin; Animals; Glucagon; Glucosamine; Glycerol; Glycogen; Glycolysis; Hypoxia; In Vitro Techniques; Lactates; Lipolysis; Myocardium; Rats | 1990 |
Inhibitory effect of novel 1-deoxynojirimycin derivatives on HIV-1 replication.
Topics: 1-Deoxynojirimycin; Blotting, Western; Cell Line; Giant Cells; Glucosamine; HIV Envelope Protein gp120; HIV Envelope Protein gp41; HIV-1; Humans; Protein Processing, Post-Translational; Virus Replication | 1990 |
Inhibition of N-glycan processing affects iodide organification in porcine thyroid cells.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Cells, Cultured; Depression, Chemical; Glucosamine; Hydrogen Peroxide; Iodide Peroxidase; Iodides; Mannosidases; Membrane Proteins; Polysaccharides; Swainsonine; Swine; Thyroid Gland | 1990 |
Biological activities of cyclophellitol.
Topics: 1-Deoxynojirimycin; Animals; Anti-Bacterial Agents; beta-Glucosidase; Binding, Competitive; Body Weight; Cell Line; Cyclohexanols; Female; Glucosamine; Glucosylceramidase; Indolizines; Mice; Microsomes; Tumor Cells, Cultured | 1990 |
Secretion of rat hepatic lipase is blocked by inhibition of oligosaccharide processing at the stage of glucosidase I.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Glucosidases; Animals; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Glucosamine; Glycoside Hydrolase Inhibitors; Glycosylation; Indolizines; Lipase; Liver; Male; Oligosaccharides; Rats; Rats, Inbred Strains; Swainsonine; Tunicamycin | 1990 |
The glycoprotein-processing inhibitors bromoconduritol and N-methyl-1-deoxynojirimycin alter the adhesion phenotype of skeletal myoblasts.
Topics: 1-Deoxynojirimycin; Amino Acid Sequence; Animals; Cell Adhesion; Cell Differentiation; Cell Fusion; Chick Embryo; Collagen; Cyclohexenes; Extracellular Matrix; Fibronectins; Glucosamine; Glycosylation; Inositol; Integrins; Laminin; Molecular Sequence Data; Muscles; Phenotype; Protein Processing, Post-Translational; Rats; Stem Cells | 1990 |
Demonstration that Golgi endo-alpha-D-mannosidase provides a glucosidase-independent pathway for the formation of complex N-linked oligosaccharides of glycoproteins.
Topics: 1-Deoxynojirimycin; Carbohydrate Sequence; Carcinoma, Hepatocellular; Cell Line; Glucosamine; Glucosidases; Glycoproteins; Golgi Apparatus; Humans; Kinetics; Liver Neoplasms; Mannosidases; Oligosaccharides; Tumor Cells, Cultured | 1990 |
Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.
Topics: 1-Deoxynojirimycin; Antiviral Agents; Cell Line; Concanavalin A; Glucosamine; HIV Envelope Protein gp120; HIV-1; Humans; Lectins; Molecular Structure; Oligosaccharides | 1990 |
Attenuation of HIV-1 infectivity by an inhibitor of oligosaccharide processing.
Topics: 1-Deoxynojirimycin; Amino Sugars; Antiviral Agents; Glucosamine; Glucosidases; HIV-1; Humans; Oligosaccharides; Virulence | 1990 |
Clearance of acute-phase plasma proteins with no, high-mannose-, hybrid-, or complex type oligosaccharide side chains by the isolated perfused rat liver.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha 1-Antitrypsin; alpha-Macroglobulins; Animals; Blood Proteins; Cells, Cultured; Glucosamine; Glycosylation; Kinetics; Liver; Mannose; Oligosaccharides; Orosomucoid; Rats; Swainsonine | 1986 |
Influence of an absorbable alpha-glucosidase inhibitor (Bay o 1248) on the endocrine and exocrine pancreas of the rat.
Topics: 1-Deoxynojirimycin; Amylases; Animals; Body Weight; Glucosamine; Glycoside Hydrolase Inhibitors; Insulin; Islets of Langerhans; Male; Pancreas; Rats; Rats, Inbred Strains; Trypsin | 1986 |
A membrane-anchored form but not the secretory form of human chorionic gonadotropin-alpha chain acquires polylactosaminoglycan.
Topics: 1-Deoxynojirimycin; Amino Sugars; Animals; Cell Line; Chromatography, Gel; Glucosamine; Glycoprotein Hormones, alpha Subunit; Glycosylation; Haplorhini; Humans; Methionine; Molecular Weight; Pituitary Hormones, Anterior; Polymers; Polysaccharides | 1988 |
Differential carbohydrate processing and secretion of thyrotropin and free alpha subunit. Effects of 1-deoxynojirimycin.
Topics: 1-Deoxynojirimycin; Animals; Carbohydrate Metabolism; Chromatography, High Pressure Liquid; Glucosamine; Glycoprotein Hormones, alpha Subunit; Hexosaminidases; Kinetics; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Models, Biological; Pituitary Gland; Pituitary Hormones, Anterior; Thyroid Diseases; Thyroid Neoplasms; Thyrotropin | 1988 |
Antibody-independent, complement-mediated enhancement of HIV-1 infection by mannosidase I and II inhibitors.
Topics: 1-Deoxynojirimycin; Alkaloids; Cells, Cultured; Complement C3; Complement Factor B; Complement System Proteins; Cytopathogenic Effect, Viral; Fluorescent Antibody Technique; Glucosamine; Glucosidases; Glycosylation; HIV-1; Humans; Mannosidases; RNA-Directed DNA Polymerase; Swainsonine | 1989 |
Effect of the alpha-glucosidase inhibitor N-hydroxyethyl-1-deoxynojirimycin (Bay m 1099) on the biosynthesis of liver secretory glycoproteins.
Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; alpha 1-Antitrypsin; Animals; Electrophoresis, Polyacrylamide Gel; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Imino Pyranoses; In Vitro Techniques; Liver; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Orosomucoid; Precipitin Tests; Rats; Rats, Inbred Strains | 1989 |
Pleiotropic resistance to glycoprotein processing inhibitors in Chinese hamster ovary cells. The role of a novel mutation in the asparagine-linked glycosylation pathway.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Glucosidases; Animals; Asparagine; Cell Line; Cricetinae; Dolichol Phosphates; Drug Resistance; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Glycosylation; Indolizines; Mannosidases; Mutation; Oligosaccharides; Ovary; Phenotype; Swainsonine | 1989 |
The relation between glycosylation and activity of guinea pig lipoprotein lipase.
Topics: 1-Deoxynojirimycin; Adipose Tissue; Animals; Enzyme Activation; Glucosamine; Glycoproteins; Guinea Pigs; Hexosaminidases; Lipoprotein Lipase; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Myocardium; Precipitin Tests; Structure-Activity Relationship; Time Factors | 1989 |
Differential glycosylation of polymeric and monomeric IgM.
Topics: 1-Deoxynojirimycin; Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Glucosamine; Glycosylation; Hybridomas; Immunoglobulin M; Mice; Mutation; Polymers | 1989 |
Differential extractability of influenza virus hemagglutinin during intracellular transport in polarized epithelial cells and nonpolar fibroblasts.
Topics: 1-Deoxynojirimycin; Animals; Biological Transport; Cell Line; Cell Membrane; Chemical Phenomena; Chemistry; Epithelium; Fibroblasts; Fluorescent Antibody Technique; Glucosamine; Golgi Apparatus; Hemagglutinins, Viral; Influenza A virus; Solubility | 1989 |
O- and N-glycosylation lead to different molecular mass forms of human monocyte interleukin-6.
Topics: 1-Deoxynojirimycin; alpha-N-Acetylgalactosaminidase; Cells, Cultured; Glucosamine; Glycosylation; Hexosaminidases; Humans; Immunosorbent Techniques; Interleukin-6; Interleukins; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Monocytes; Neuraminidase; Tunicamycin | 1989 |
Non-carrier-mediated uptake of the mannosidase I inhibitor 1-deoxymannojirimycin by K562 erythroleukemic cells.
Topics: 1-Deoxynojirimycin; Biological Transport; Cell Line; Glucosamine; Glucose; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mannose; Mannosidases; Tritium | 1989 |
Inhibitors of cellular proteolysis cause increased secretion from parathyroid cells.
Topics: 1-Deoxynojirimycin; Adenine; Animals; Calcium; Calcium-Binding Proteins; Cattle; Cells, Cultured; Chloroquine; Chromogranin A; Chromogranins; Exocytosis; Glucosamine; Parathyroid Glands; Parathyroid Hormone; Protease Inhibitors; Radioimmunoassay | 1989 |
The antiglycogenolytic action of 1-deoxynojirimycin results from a specific inhibition of the alpha-1,6-glucosidase activity of the debranching enzyme.
Topics: 1-Deoxynojirimycin; 1,4-alpha-Glucan Branching Enzyme; Cytosol; Glucosamine; Glucose; Glucosyltransferases; Glycogen; Glycoside Hydrolase Inhibitors; Liver; Molecular Structure; Phosphorylation | 1989 |
Inhibitors of asparagine-linked oligosaccharide processing alter the kinetics of the nicotinic acetylcholine receptor.
Topics: 1-Deoxynojirimycin; Alkaloids; Asparagine; Clone Cells; Electrophysiology; Glucosamine; Indolizines; Kinetics; Oligosaccharides; Receptors, Nicotinic; Swainsonine | 1989 |
Effects of tunicamycin and N-linked oligosaccharide-processing inhibitors on the morphology of cultured porcine thyroid cells.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; beta-Glucosidase; Cell Adhesion; Cell Membrane; Cells, Cultured; Glucosamine; Glycopeptides; Indolizines; Mannosidases; Oligosaccharides; Sucrase; Swainsonine; Swine; Thyroid Gland; Tunicamycin | 1989 |
Study of the N-glycoprotein biosynthesis through dolichol intermediates in the mitochondrial membranes.
Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; Animals; Cell Fractionation; Chromatography, Liquid; Dolichols; Glucosamine; Glycoproteins; In Vitro Techniques; Intracellular Membranes; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Mitochondria | 1989 |
Mulberry roots and seeds may be effective in the treatment of AIDS.
Topics: 1-Deoxynojirimycin; Acquired Immunodeficiency Syndrome; Glucosamine; Humans; Plants, Medicinal; Sucrase | 1989 |
Butyrophilin of milk lipid globule membrane contains N-linked carbohydrates and cross-links with xanthine oxidase.
Topics: 1-Deoxynojirimycin; Amidohydrolases; Animals; Anti-Bacterial Agents; Binding Sites; Butyrophilins; Carbohydrates; Cattle; Electrophoresis; Female; Glucosamine; Hexosaminidases; Lipids; Membrane Glycoproteins; Membrane Lipids; Membrane Proteins; Milk; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Rats; Xanthine Oxidase | 1989 |
Asynchronous transport to the cell surface of intestinal brush border hydrolases is not due to differential trimming of N-linked oligosaccharides.
Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; alpha-Glucosidases; Biological Transport; Concanavalin A; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Glucosamine; Glycoside Hydrolase Inhibitors; Glycosylation; Golgi Apparatus; Humans; Hydrolases; Intestine, Small; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Microvilli; Oligosaccharides; Sucrase; Sucrase-Isomaltase Complex; Tumor Cells, Cultured | 1989 |
Effect of inhibitors of glycoprotein processing on integrin and the adhesion of myoblasts to extracellular matrix proteins.
Topics: 1-Deoxynojirimycin; Animals; Cell Adhesion; Cells, Cultured; Chick Embryo; Cyclohexenes; Extracellular Matrix; Fibronectins; Glucosamine; Glycoproteins; Glycoside Hydrolases; Inositol; Integrins; Kinetics; Laminin; Membrane Glycoproteins; Muscles; Protein Processing, Post-Translational; Rats | 1989 |
Catabolic pathway of oligosaccharide-diphospho-dolichol. Subcellular sites of the degradation of the oligomannoside moiety.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Endoplasmic Reticulum; Fibroblasts; Glucosamine; Glycosylation; Humans; Indolizines; Mice; Oligosaccharides; Spleen; Swainsonine | 1989 |
Analysis of the role of glycosylation of the human fibronectin receptor.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Antibodies, Monoclonal; Cells, Cultured; Fibroblasts; Fibronectins; Glucosamine; Glycopeptides; Glycosylation; Humans; Kinetics; Male; Methionine; Protein Processing, Post-Translational; Receptors, Fibronectin; Receptors, Immunologic; Skin | 1989 |
Differential effect of inhibitors of oligosaccharide processing on the secretion of thyrotropin from dispersed rodent pituitary cells.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Anti-Bacterial Agents; Glucosamine; Glycoside Hydrolases; Glycosylation; Hypothyroidism; Male; Mannosidases; Mice; Oligosaccharides; Pituitary Gland; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; Swainsonine; Thyroid Neoplasms; Thyroidectomy; Thyrotropin | 1989 |
Inhibition of yeast exoglucanases by glucosidase inhibitors.
Topics: 1-Deoxynojirimycin; Alkaloids; Anti-Bacterial Agents; beta-Glucosidase; Binding, Competitive; Candida albicans; Glucan 1,3-beta-Glucosidase; Glucans; Glucosamine; Glucosidases; Glucosides; Indolizines; Polysaccharides; Saccharomyces cerevisiae | 1989 |
Inhibition of beta-glucosidase by imidazoles.
Topics: 1-Deoxynojirimycin; beta-Glucosidase; Glucosamine; Glucosidases; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Protein Binding; Structure-Activity Relationship | 1989 |
Effects of the alpha-mannosidase inhibitors, 1,4-dideoxy-1,4-imino-D-mannitol and swainsonine, on glycoprotein catabolism in cultured macrophages.
Topics: 1-Deoxynojirimycin; alpha-Mannosidase; alpha-Mannosidosis; Animals; Carbohydrate Sequence; Cells, Cultured; Chromatography, High Pressure Liquid; Glucosamine; Glycoproteins; Humans; Macrophages; Mannosidases; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Oligosaccharides; Swainsonine | 1989 |
Targeting of lysosomal acid phosphatase with altered carbohydrate.
Topics: 1-Deoxynojirimycin; Acid Phosphatase; Alkaloids; Ammonium Chloride; Autoradiography; Biological Transport; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Glucosamine; Intracellular Membranes; Lysosomes; Membrane Proteins; Oligosaccharides; Receptor, IGF Type 2; Receptors, Cell Surface; Receptors, Somatomedin; Sodium Dodecyl Sulfate; Sulfur Radioisotopes; Swainsonine; Tunicamycin | 1989 |
Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Glucosidases; Cell Line; Endoplasmic Reticulum; Glucosamine; Glycoproteins; Glycoside Hydrolase Inhibitors; Glycosylation; Golgi Apparatus; HIV Antigens; HIV Envelope Protein gp120; HIV Envelope Protein gp160; HIV Envelope Protein gp41; HIV-1; Mannose; Mannosidases; Oligosaccharides; Retroviridae Proteins; Swainsonine; Tunicamycin; Viral Envelope Proteins | 1989 |
Processing and secretion of envelope glycoproteins of human immunodeficiency virus type 1 in the presence of trimming glucosidase inhibitor deoxynojirimycin.
Topics: 1-Deoxynojirimycin; Cell Fusion; Cell Line; Electrophoresis, Polyacrylamide Gel; Glucosamine; HIV Envelope Protein gp120; HIV Envelope Protein gp160; HIV-1; Humans; Protein Processing, Post-Translational; Retroviridae Proteins; Viral Envelope Proteins | 1989 |
Effects of N-hydroxyethyl-1-deoxynojirimycin (BAY m 1099) on the activity of neutral- and acid alpha-glucosidases in human fibroblasts and HepG2 cells.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Binding, Competitive; Carcinoma, Hepatocellular; Fibroblasts; Glucosamine; Glycogen; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Immunohistochemistry; Kinetics; Liver Neoplasms; Lysosomes; Microscopy, Electron; Molecular Weight; Tumor Cells, Cultured | 1989 |
Microbial epimerization of 1-deoxynojirimycin to 1-deoxymannojirimycin.
Topics: 1-Deoxynojirimycin; alpha-Galactosidase; alpha-Mannosidase; Chemical Phenomena; Chemistry, Physical; Fabaceae; Glucosamine; Mannosidases; Plants, Medicinal; Rhizobium; Stereoisomerism | 1989 |
Several new AIDS drugs being tested.
Topics: 1-Deoxynojirimycin; Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; CD4 Antigens; Drug Therapy, Combination; Glucosamine; Humans; Interferon Type I; Sarcoma, Kaposi; Zalcitabine; Zidovudine | 1989 |
Metabolic consequences of the alpha-glucosidase inhibitor BAY-M-1099 given to nondiabetic and diabetic rats fed a high-carbohydrate diet.
Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diet; Dietary Carbohydrates; Glucosamine; Glycoside Hydrolase Inhibitors; Glycosuria; Imino Pyranoses; Male; Rats; Rats, Inbred Strains; Sucrose; Triglycerides | 1989 |
The effect of acarbose and miglitol (BAY-M-1099) on postprandial glucose levels following ingestion of various sources of starch by nondiabetic and streptozotocin-induced diabetic rats.
Topics: 1-Deoxynojirimycin; Acarbose; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Eating; Glucosamine; Glucose; Glucosidases; Imino Pyranoses; Insulin; Male; Rats; Starch; Trisaccharides | 1989 |
Experimental treatments for HIV-infected patients.
Topics: 1-Deoxynojirimycin; Antiviral Agents; Glucosamine; HIV Envelope Protein gp160; HIV Seropositivity; Humans; Immunotherapy; Recombinant Proteins; Retroviridae Proteins; Vaccines, Synthetic; Viral Envelope Proteins; Viral Vaccines | 1989 |
Recycling glycoproteins do not return to the cis-Golgi.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Carcinoma, Hepatocellular; Cell Line, Transformed; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Glucosamine; Glycoproteins; Golgi Apparatus; HLA Antigens; HLA-D Antigens; Humans; Immunoassay; Isoelectric Focusing; Leukemia, Erythroblastic, Acute; Liver Neoplasms; Mannosidases; Neuraminidase; Receptors, Transferrin; Transferrin; Tumor Cells, Cultured | 1988 |
Use of 1-deoxymannojirimycin to show that complex oligosaccharides regulate cellular distribution of the alpha 1-adrenergic receptor glycoprotein in BC3H1 muscle cells.
Topics: 1-Deoxynojirimycin; Affinity Labels; Animals; Cells, Cultured; Epinephrine; Glucosamine; Glycoproteins; Mice; Muscles; Oligosaccharides; Phentolamine; Prazosin; Receptors, Adrenergic, alpha | 1988 |
Role of the Na,K-ATPase beta-subunit in the cellular accumulation and maturation of the enzyme as assessed by glycosylation inhibitors.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Cell Line; Glucosamine; Glycoproteins; Glycosylation; Precipitin Tests; Protein Conformation; Protein Processing, Post-Translational; Sodium-Potassium-Exchanging ATPase; Swainsonine; Trypsin; Tunicamycin | 1988 |
Castanospermine and other plant alkaloid inhibitors of glucosidase activity block the growth of HIV.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; beta-Glucosidase; Cattle; Glucosamine; Glucosidases; HIV; Humans; Imino Furanoses; In Vitro Techniques; Indolizines; Mannitol; Plants, Medicinal; Pyrrolidines | 1987 |
Cell type dependent inhibition of transport of cathepsin D in HepG2 cells and fibroblasts exposed to deoxy-manno-nojirimycin and deoxynojirimycin.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Biological Transport, Active; Cathepsin D; Cell Line; Cells, Cultured; Culture Media; Depression, Chemical; Fibroblasts; Glucosamine; Humans; Methionine; Subcellular Fractions | 1985 |
Glucosylceramidase from calf spleen. Characterization of its active site with 4-n-alkylumbelliferyl beta-glucosides and N-alkyl derivatives of 1-deoxynojirimycin.
Topics: 1-Deoxynojirimycin; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Detergents; Glucosamine; Glucosidases; Glucosides; Glucosylceramidase; Glycosides; Hot Temperature; Kinetics; Spleen; Substrate Specificity; Umbelliferones | 1985 |
The use of 1-deoxymannojirimycin to evaluate the role of various alpha-mannosidases in oligosaccharide processing in intact cells.
Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Anti-Bacterial Agents; Cell Line; Cells, Cultured; Glucosamine; Glycopeptides; Hydroxymethylglutaryl CoA Reductases; Kinetics; Liver; Mannosidases; Oligosaccharides; Rats; Substrate Specificity | 1986 |
Disruption of oligosaccharide processing in murine tumor cells inhibits their susceptibility to lysis by activated mouse macrophages.
Topics: 1-Deoxynojirimycin; Animals; Cell Line; Female; Glucosamine; Glycoproteins; Macrophages; Mice; Neoplasm Proteins; Neoplasms, Experimental; Protein Processing, Post-Translational | 1986 |
Inhibition of N-linked oligosaccharide processing does not prevent the secretion of thyroglobulin. A study with swainsonine and deoxynojirimycin.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Mannosidase; Animals; Glucosamine; Glycoside Hydrolases; Hexosaminidases; Leucine; Mannose; Mannosidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Oligosaccharides; Pronase; Swainsonine; Swine; Thyroglobulin; Thyroid Gland | 1986 |
Purification and characterization of a neutral processing mannosidase from calf liver acting on (Man)9(GlcNAc)2 oligosaccharides.
Topics: 1-Deoxynojirimycin; Acetylglucosamine; Animals; Cations, Divalent; Cattle; Chromatography; Glucosamine; Hydrogen-Ion Concentration; Kinetics; Mannose; Mannosidases; Microsomes, Liver; Oligosaccharides; Solubility; Substrate Specificity | 1986 |
Characterization of calf liver glucosidase I and its inhibition by basic sugar analogs.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Cattle; Glucosamine; Glucosidases; Glycoside Hydrolase Inhibitors; Hydrogen-Ion Concentration; Kinetics; Liver; Molecular Weight; Oligosaccharides; Substrate Specificity | 1986 |
Steroid sulfatase. Biosynthesis and processing in normal and mutant fibroblasts.
Topics: 1-Deoxynojirimycin; Cells, Cultured; Endoplasmic Reticulum; Fibroblasts; Glucosamine; Golgi Apparatus; Humans; Ichthyosis; Lysosomes; Mannose; Molecular Weight; Mutation; Oligosaccharides; Steryl-Sulfatase; Sulfatases | 1986 |
Human acid beta-glucosidase: affinity purification of the normal placental and Gaucher disease splenic enzymes on N-alkyl-deoxynojirimycin-sepharose.
Topics: 1-Deoxynojirimycin; Amino Acid Sequence; beta-Glucosidase; Chromatography, Affinity; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Female; Gaucher Disease; Glucosamine; Glucosidases; Humans; Peptide Fragments; Placenta; Pregnancy; Spleen | 1986 |
Inhibition of N-linked oligosaccharide trimming mannosidases blocks human B cell development.
Topics: 1-Deoxynojirimycin; Alkaloids; B-Lymphocytes; Cell Division; Cell Survival; Cells, Cultured; DNA Replication; Glucosamine; HLA Antigens; Humans; Kinetics; Lymphocyte Activation; Mannosidases; Oligosaccharides; Swainsonine | 1986 |
Effects of tunicamycin, N-methyl-1-deoxynojirimycin, and manno-1-deoxynojirimycin on the biosynthesis of lactosaminoglycans in F9 teratocarcinoma cells.
Topics: 1-Deoxynojirimycin; Amino Sugars; Anti-Bacterial Agents; Cell Line; Galactose; Glucosamine; Glycopeptides; Mannose; Oligosaccharides; Polysaccharides; Teratoma; Tritium; Tunicamycin | 1986 |
Synthesis of 1-deoxynojirimycin and 1-deoxymannojirimycin.
Topics: 1-Deoxynojirimycin; Chemical Phenomena; Chemistry; Glucosamine; Immunosuppressive Agents; In Vitro Techniques | 1986 |
The effects of inhibiting oligosaccharide trimming by 1-deoxynojirimycin on the nicotinic acetylcholine receptor.
Topics: 1-Deoxynojirimycin; Animals; Bungarotoxins; Cell Membrane; Cells, Cultured; Glucosamine; Kinetics; Macromolecular Substances; Mice; Oligosaccharides; Protein Processing, Post-Translational; Receptors, Nicotinic | 1986 |
Studies on the effect of glycoprotein processing inhibitors on fusion of L6 myoblast cell lines.
Topics: 1-Deoxynojirimycin; Alkaloids; Cell Fusion; Cell Line; Concanavalin A; Glucosamine; Glycoproteins; Indolizines; Mannose; Muscles; Oligosaccharides; Swainsonine; Wheat Germ Agglutinins | 1987 |
Different effects of the glucosidase inhibitors 1-deoxynojirimycin, N-methyl-1-deoxynojirimycin and castanospermine on the glycosylation of rat alpha 1-proteinase inhibitor and alpha 1-acid glycoprotein.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha 1-Antitrypsin; Animals; Blood Proteins; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Glucosamine; Glucosidases; Glycosylation; Indolizines; Liver; Oligosaccharides; Orosomucoid; Rats | 1986 |
Inhibition of myoblast fusion by the glucosidase inhibitor N-methyl-1-deoxynojirimycin, but not by the mannosidase inhibitor 1-deoxymannojirimycin.
Topics: 1-Deoxynojirimycin; Animals; Cell Fusion; Cell Line; Cell Membrane; Glucosamine; Glucosidases; Glycopeptides; Mannosidases; Muscles; Oligosaccharides; Rats | 1986 |
Efficient routing of glucocerebrosidase to lysosomes requires complex oligosaccharide chain formation.
Topics: 1-Deoxynojirimycin; Alkaloids; beta-N-Acetylhexosaminidases; Cell Compartmentation; Cell Line; Glucosamine; Glucosidases; Glucosylceramidase; Glycoproteins; Golgi Apparatus; Humans; Lysosomes; Membrane Glycoproteins; Monocytes; Protein Processing, Post-Translational; Swainsonine | 1986 |
The effect of glycoprotein-processing inhibitors on the secretion of glycoproteins by Madin-Darby canine kidney cells.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Cell Line; Dogs; Glucosamine; Glycopeptides; Glycoproteins; Glycoside Hydrolases; Indolizines; Kidney; Kinetics; Mannose; Swainsonine | 1987 |
Catabolic pathway of oligosaccharide-diphospho-dolichol. Study of the fate of the oligosaccharidic moiety in mouse splenocytes.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Glucosamine; Glucosidases; Indolizines; Kinetics; Mannose; Mice; Oligosaccharides; Polyisoprenyl Phosphate Oligosaccharides; Polyisoprenyl Phosphate Sugars; Spleen; Tritium; Tunicamycin | 1987 |
Human acid beta-glucosidase: use of inhibitors, alternative substrates and amphiphiles to investigate the properties of the normal and Gaucher disease active sites.
Topics: 1-Deoxynojirimycin; Amines; beta-Glucosidase; Binding Sites; Binding, Competitive; Ceramides; Female; Gaucher Disease; Glucosamine; Glucosidases; Glucosides; Humans; Kinetics; Octoxynol; Placenta; Polyethylene Glycols; Pregnancy; Sphingosine; Spleen; Structure-Activity Relationship | 1987 |
The chemistry of the 1-deoxynojirimycin system. Synthesis of 2-acetamido-1,2-dideoxynojirimycin from 1-deoxynojirimycin.
Topics: 1-Deoxynojirimycin; Antibodies; Glucosamine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Optical Rotation | 1987 |
Effect of glycoprotein-processing inhibitors on the mouse IgE binding capacity of rat basophilic leukemia cells.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Anti-Bacterial Agents; Basophils; Enzyme-Linked Immunosorbent Assay; Glucosamine; Glucosidases; Glycoproteins; Immunoglobulin E; Indolizines; Leukemia, Experimental; Rats; Receptors, Fc; Receptors, IgE; Receptors, Immunologic; Swainsonine | 1987 |
Effects of castanospermine and 1-deoxynojirimycin on insulin receptor biogenesis. Evidence for a role of glucose removal from core oligosaccharides.
Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; Alkaloids; Cell Line; Chromatography, High Pressure Liquid; Glucosamine; Glucose; Glucosidases; Humans; Indolizines; Insulin; Leucine; Mannose; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Oligosaccharides; Receptor, Insulin | 1987 |
Glucose trimming and mannose trimming affect different phases of the maturation of Sindbis virus in infected BHK cells.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Cell Line; Culture Media; Glucosamine; Glucose; Glucosidases; Glycoproteins; Glycosylation; Mannose; Mannosidases; Microscopy, Electron; Protein Processing, Post-Translational; Sindbis Virus; Viral Proteins | 1987 |
Antiretroviral activity of castanospermine and deoxynojirimycin, specific inhibitors of glycoprotein processing.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Antiviral Agents; Cell Transformation, Viral; Cells, Cultured; DNA Replication; Glucosamine; Glycoproteins; Glycoside Hydrolases; Indolizines; Mice; Moloney murine leukemia virus; Protein Processing, Post-Translational; Viral Plaque Assay; Virus Replication | 1987 |
Active human erythropoietin expressed in insect cells using a baculovirus vector: a role for N-linked oligosaccharide.
Topics: 1-Deoxynojirimycin; Animals; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; DNA; Erythropoietin; Fibroblasts; Genetic Vectors; Glucosamine; Humans; Insect Viruses; Insecta; Oligosaccharides; Protein Processing, Post-Translational; Recombinant Fusion Proteins | 1987 |
Membrane glycoproteins are involved in the differentiation of the BC3H1 muscle cell line.
Topics: 1-Deoxynojirimycin; Acetylglucosamine; Alkaloids; Animals; Cell Differentiation; Cell Line; Creatine Kinase; Deoxy Sugars; Deoxyglucose; Enzyme Induction; Glucosamine; Glycoproteins; Indolizines; Leupeptins; Membrane Glycoproteins; Membrane Proteins; Mice; Muscles; Oligosaccharides; Swainsonine; Tunicamycin | 1987 |
Asparagine-linked oligosaccharides of BHK cells treated with inhibitors of oligosaccharide processing.
Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Asparagine; Cell Line; Chromatography, Affinity; Chromatography, Gel; Cricetinae; Glucosamine; Glucose; Glycopeptides; Glycosylation; Lectins; Mannose; Mannosidases; Oligosaccharides | 1987 |
Inhibitory mechanism of acarbose and 1-deoxynojirimycin derivatives on carbohydrases in rat small intestine.
Topics: 1-Deoxynojirimycin; Acarbose; alpha-Amylases; Animals; Anti-Bacterial Agents; Female; Glucosamine; Glycoside Hydrolases; Hypoglycemic Agents; Imino Pyranoses; In Vitro Techniques; Intestine, Small; Kinetics; Microvilli; Pancreas; Rats; Rats, Inbred Strains; Trisaccharides | 1987 |
Isolation of a cytosolic beta-glucosidase from calf liver and characterization of its active site with alkyl glucosides and basic glycosyl derivatives.
Topics: 1-Deoxynojirimycin; Animals; beta-Glucosidase; Cattle; Cytosol; Glucosamine; Glucosidases; Hydrogen-Ion Concentration; Kinetics; Liver; Psychosine; Substrate Specificity | 1988 |
1-Deoxynojirimycin and related compounds inhibit glycogenolysis in the liver without affecting the concentration of phosphorylase a.
Topics: 1-Deoxynojirimycin; Animals; Dose-Response Relationship, Drug; Glucagon; Glucosamine; Glycogen Synthase; Glycoside Hydrolase Inhibitors; Imino Pyranoses; Liver; Liver Glycogen; Male; Phosphorylase a; Phosphorylases; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1988 |
Structural properties of a soluble bioactive precursor for transforming growth factor-alpha.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Anti-Bacterial Agents; Carbohydrates; Cell Line; Cell Transformation, Neoplastic; Glucosamine; Growth Substances; Indolizines; Membrane Glycoproteins; Protein Precursors; Retroviridae; Swainsonine; Transforming Growth Factor alpha; Tunicamycin | 1988 |
Glycoprotein modifications of sarcoma L-1 tumor cells by tunicamycin, swainsonine, bromoconduritol or 1-desoxynojirimycin treatment inhibits their metastatic lung colonization in Balb/c-mice.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Carbohydrates; Cyclohexenes; Glucosamine; Glycoproteins; Inositol; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Sarcoma, Experimental; Swainsonine; Tunicamycin | 1988 |
The purification and characterization of mannosidase IA from rat liver Golgi membranes.
Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Glucosamine; Golgi Apparatus; Hexosaminidases; Isoenzymes; Liver; Male; Mannose; Mannosidases; Molecular Weight; Octoxynol; Polyethylene Glycols; Rats; Rats, Inbred Strains | 1988 |
Allele and locus-specific differences in cell surface expression and the association of HLA class I heavy chain with beta 2-microglobulin: differential effects of inhibition of glycosylation on class I subunit association.
Topics: 1-Deoxynojirimycin; Alleles; beta 2-Microglobulin; Biological Transport; Cell Membrane; Glucosamine; Glycosylation; HLA Antigens; Humans; Kinetics; Protein Conformation; Protein Processing, Post-Translational; Tunicamycin | 1988 |
Post-translational protein modification in the endoplasmic reticulum. Demonstration of fatty acylase and deoxymannojirimycin-sensitive alpha-mannosidase activities.
Topics: 1-Deoxynojirimycin; Acetyltransferases; Acylation; alpha-Mannosidase; Animals; Anti-Bacterial Agents; Cell Line; Endoplasmic Reticulum; Genes; Glucosamine; Mannosidases; Palmitic Acid; Palmitic Acids; Protein Multimerization; Protein Processing, Post-Translational; Transcription, Genetic | 1988 |
1-Deoxymannojirimycin inhibits Golgi-mediated processing of glycoprotein in Xenopus oocytes.
Topics: 1-Deoxynojirimycin; Animals; Female; Glucosamine; Glycoproteins; Golgi Apparatus; Oocytes; Protein Biosynthesis; RNA, Messenger; Xenopus | 1988 |
Study of beta-glucosidase from Helix pomatia by active site-directed inhibitors.
Topics: 1-Deoxynojirimycin; Animals; beta-Glucosidase; Glucosamine; Glucosidases; Helix, Snails; Hydrogen-Ion Concentration; Inositol; Kinetics; Substrate Specificity | 1988 |
Studies on the effect of 1-deoxynojirimycin on the release of albumin, sialyltransferase and alpha 1 acid glycoprotein from liver slices from normal and inflamed rats.
Topics: 1-Deoxynojirimycin; Acetylglucosamine; Albumins; Animals; beta-D-Galactoside alpha 2-6-Sialyltransferase; Glucosamine; Glycoproteins; Hepatitis, Animal; Liver; Male; Orosomucoid; Rats; Sialyltransferases; Wheat Germ Agglutinins | 1988 |
Inhibition of mannosidase in hybridomas yields monoclonal antibodies with greater capacity for carbohydrate labeling.
Topics: 1-Deoxynojirimycin; Acetylglucosamine; Acetylglucosaminidase; Animals; Antibodies, Monoclonal; Antigens; Carbohydrates; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Glucosamine; Humans; Hybridomas; Indium Radioisotopes; Mannose; Mannosidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Neoplasms, Experimental; Tumor Cells, Cultured | 1988 |
Modulation of oligosaccharide processing in an exocrine secretory glycoprotein of rat parotid cells by beta-adrenoreceptor activation.
Topics: 1-Deoxynojirimycin; Animals; Glucosamine; Glycoproteins; Isoproterenol; Male; Oligosaccharides; Parotid Gland; Rats; Rats, Inbred Strains | 1988 |
Isolation of 1,5-dideoxy-1,5-imino-D-mannitol from culture broth of Streptomyces species.
Topics: 1-Deoxynojirimycin; Chemical Phenomena; Chemistry; Culture Media; Glucosamine; Mannosidases; Streptomyces | 1988 |
Inhibition of intestinal alpha-glucosidase and postprandial hyperglycemia by N-substituted moranoline derivatives.
Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Food; Glucosamine; Glycoside Hydrolase Inhibitors; Hyperglycemia; Intestines; Rabbits; Structure-Activity Relationship | 1988 |
Effects of inhibitors of glycoprotein processing on oligodendroglial differentiation in primary cultures of embryonic rat brain cells.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Brain; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors; Glucosamine; Indolizines; Neuroglia; Oligodendroglia; Oligosaccharides; Rats; Time Factors | 1988 |
Investigation of the role of glycans for the biological activity of Semliki Forest virus grown in Aedes albopictus cells using inhibitors of asparagine-linked oligosaccharides trimming.
Topics: 1-Deoxynojirimycin; Aedes; Alkaloids; Animals; Glucans; Glucosamine; Glycoproteins; Glycoside Hydrolases; Glycosylation; Hexosaminidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Membrane Fusion; Molecular Weight; Semliki forest virus; Swainsonine; Tunicamycin; Viral Envelope Proteins; Virus Replication | 1988 |
Response of aggregating chick corneal cells to modifiers of N-linked oligosaccharides, endoglycosidase H and deoxymannojirimycin.
Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; Animals; Cell Aggregation; Cells, Cultured; Chick Embryo; Concanavalin A; Cornea; Desmosomes; Glucosamine; Hexosaminidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Microscopy, Electron | 1988 |
Mechanism-based inactivation of rabbit muscle phosphoglucomutase by nojirimycin 6-phosphate.
Topics: 1-Deoxynojirimycin; Animals; Catalysis; Enzyme Activation; Glucosamine; Glucose-6-Phosphate; Glucosephosphates; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Muscles; Phosphates; Phosphoglucomutase; Phosphorylation; Rabbits | 1988 |
Inhibition of myoblast fusion by bromoconduritol.
Topics: 1-Deoxynojirimycin; Animals; Anti-Bacterial Agents; Catalysis; Cell Fusion; Cell Line; Cyclohexenes; Glucosamine; Glucosidases; Inositol; Lactoperoxidase; Membrane Proteins; Molecular Weight; Muscles; Rats | 1988 |
The mannosidase inhibitors 1-deoxymannojirimycin and swainsonine have no effect on the biosynthesis and infectivity of Rous sarcoma virus.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Antiviral Agents; Avian Sarcoma Viruses; Glucosamine; Glycopeptides; Glycoproteins; Mannosidases; Molecular Weight; Oligosaccharides; Swainsonine; Viral Proteins | 1985 |
The effects of processing inhibitors of N-linked oligosaccharides on the intracellular migration of glycoprotein E2 of mouse hepatitis virus and the maturation of coronavirus particles.
Topics: 1-Deoxynojirimycin; Acylation; Alkaloids; Animals; Antibodies, Monoclonal; Cell Compartmentation; Coronaviridae; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Glucosamine; Glucosidases; Indolizines; Lactoperoxidase; Mice; Mice, Inbred BALB C; Microscopy, Electron; Murine hepatitis virus; Oligosaccharides; Swainsonine; Tunicamycin; Viral Envelope Proteins | 1985 |
Membrane traffic in animal cells: cellular glycoproteins return to the site of Golgi mannosidase I.
Topics: 1-Deoxynojirimycin; Alkaloids; Biological Transport; Cell Compartmentation; Cell Line; Glucosamine; Glycoproteins; Golgi Apparatus; Humans; Intracellular Membranes; Mannosidases; Membrane Glycoproteins; Membrane Proteins; Protein Processing, Post-Translational; Receptors, Cell Surface; Receptors, Transferrin; Swainsonine | 1986 |
Transformation by the v-fms oncogene product: role of glycosylational processing and cell surface expression.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Carbohydrate Metabolism; Cell Membrane; Cell Transformation, Viral; Cells, Cultured; Endocytosis; Gene Expression Regulation; Glucosamine; Indolizines; Oncogene Proteins, Viral; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Rats; Retroviridae; Sarcoma Viruses, Feline; Swainsonine | 1985 |
A vesicular intermediate in the transport of hepatoma secretory proteins from the rough endoplasmic reticulum to the Golgi complex.
Topics: 1-Deoxynojirimycin; alpha 1-Antitrypsin; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cytoplasmic Granules; Endoplasmic Reticulum; Glucosamine; Golgi Apparatus; Humans; Kinetics; Liver Neoplasms; Mannose; Neoplasm Proteins | 1987 |
Assembly and processing of the disulfide-linked varicella-zoster virus glycoprotein gpII(140).
Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; Alkaloids; alpha-N-Acetylgalactosaminidase; Antibodies, Monoclonal; Disulfides; Glucosamine; Glycoproteins; Herpesvirus 3, Human; Hexosaminidases; Humans; Indolizines; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Neuraminidase; Sulfates; Swainsonine; Tunicamycin; Viral Proteins | 1987 |
Effect of alpha-inhibitors on blood glucose and insulin levels.
Topics: 1-Deoxynojirimycin; Acarbose; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Middle Aged; Obesity; Reference Values; Trisaccharides | 1988 |
Chronic effects of an alpha-glucosidase inhibitor (Bay o 1248) on intestinal disaccharidase activity in normal and diabetic mice.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; beta-Galactosidase; Body Weight; Diabetes Mellitus, Experimental; Disaccharidases; Eating; Glucosamine; Glycoside Hydrolase Inhibitors; Intestine, Small; Mice; Mice, Inbred C57BL; Sucrase | 1987 |
Effect of trimming inhibitors on the secretion and biological activity of a murine IgE monoclonal antibody.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Antibodies, Monoclonal; Cell Line; Glucosamine; Glycosylation; Immunoglobulin E; Indolizines; Mice; Protein Processing, Post-Translational; Swainsonine; Tunicamycin | 1987 |
Involvement of a conidial endoglucanase and a plasma-membrane-bound beta-glucosidase in the induction of endoglucanase synthesis by cellulose in Trichoderma reesei.
Topics: 1-Deoxynojirimycin; beta-Glucosidase; Cell Membrane; Cellulose; Enzyme Induction; Glucan Endo-1,3-beta-D-Glucosidase; Gluconates; Glucosamine; Glucosidases; Glycoside Hydrolases; Lactones; Mitosporic Fungi; Trichoderma | 1987 |
Deoxynojirimycin inhibits the formation of Glc3Man9GlcNAc2-PP-dolichol in intestinal epithelial cells in culture.
Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Cell Line; Epithelium; Glucosamine; Intestinal Mucosa; Intestines; Mannose; Mannosidases; Oligosaccharides; Polyisoprenyl Phosphate Sugars; Rats | 1985 |
Comparison between 1-deoxynojirimycin and N-methyl-1-deoxynojirimycin as inhibitors of oligosaccharide processing in intestinal epithelial cells.
Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Epithelial Cells; Epithelium; Galactose; Glucosamine; Glycopeptides; In Vitro Techniques; Intestinal Mucosa; Mannosidases; Oligosaccharides; Rats | 1985 |
The effects of inhibitors of glucosidase I on the formation of Sindbis virus.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Glucosidases; Animals; Cell Line; Chick Embryo; Chromatography, High Pressure Liquid; Cricetinae; Female; Fibroblasts; Glucosamine; Glucosidases; Glycoproteins; Glycoside Hydrolase Inhibitors; Indolizines; Kidney; Ovary; Sindbis Virus; Temperature; Viral Proteins; Virus Replication | 1985 |
Effects of manno-1-deoxynojirimycin and 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine on N-linked oligosaccharide processing in intestinal epithelial cells.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Chromatography, High Pressure Liquid; Epithelium; Glucosamine; Glycoproteins; Imino Furanoses; Intestinal Mucosa; Mannitol; Oligosaccharides; Protein Processing, Post-Translational; Pyrrolidines; Rats; Structure-Activity Relationship | 1985 |
Influence of asparagine-linked oligosaccharides on tumor cell recognition in the mixed lymphocyte reaction.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Antigens, Surface; Asparagine; Carbohydrate Conformation; Cell Line; Glucosamine; H-2 Antigens; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphoma; Membrane Proteins; Mice; Mice, Inbred Strains; Neoplasm Proteins; Neuraminidase; Oligosaccharides; Spleen; Swainsonine; T-Lymphocytes; Thymus Gland | 1985 |
Secretion of high-mannose-type alpha 1-proteinase inhibitor and alpha 1-acid glycoprotein by primary cultures of rat hepatocytes in the presence of the mannosidase I inhibitor 1-deoxymannojirimycin.
Topics: 1-Deoxynojirimycin; Acrylic Resins; alpha 1-Antitrypsin; Animals; Blood Proteins; Cells, Cultured; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Glucosamine; Hexosaminidases; Immunochemistry; Liver; Mannose; Mannosidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Oligosaccharides; Orosomucoid; Rats | 1985 |
Alpha-glucosidase inhibition and timing of preprandial insulin in patients with insulin-dependent diabetes mellitus (IDDM).
Topics: 1-Deoxynojirimycin; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Eating; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Pyranoses; Insulin; Kinetics; Male | 1988 |
Adaptive responses to pharmacological inhibition of small intestinal alpha-glucosidases in the rat.
Topics: 1-Deoxynojirimycin; Adaptation, Physiological; Animals; Cecum; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Imino Pyranoses; Intestine, Small; Organ Size; Polyamines; Rats; Rats, Inbred Strains | 1987 |
Effect of an alpha-glucosidase inhibitor (BAY m 1099) on post-prandial blood glucose and insulin in type II diabetics.
Topics: 1-Deoxynojirimycin; Adult; Aged; Anti-Bacterial Agents; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucosamine; Humans; Imino Pyranoses; Insulin; Male; Middle Aged | 1986 |
Miglitol may have a blood glucose lowering effect unrelated to inhibition of alpha-glucosidase.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Male | 1987 |
Effect of the alpha-glucosidase inhibitor Bay-O-1248 on the metabolic response of nondiabetic and diabetic rats to a high-carbohydrate diet.
Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Glucosamine; Glycosuria; Male; Rats; Rats, Inbred Strains; Triglycerides | 1986 |
Transfer of nonglucosylated oligosaccharide from lipid to protein in a mammalian cell.
Topics: 1-Deoxynojirimycin; Cells, Cultured; Chromatography, Affinity; Chromatography, High Pressure Liquid; Dolichol Phosphates; Glucosamine; Lipid Metabolism; Mannose; Oligosaccharides; Proteins | 1986 |
Regulation of the absorption of dietary carbohydrate in man by two new glycosidase inhibitors.
Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Dietary Carbohydrates; Dose-Response Relationship, Drug; Glucosamine; Glycoside Hydrolases; Humans; Hydrogen; Imino Pyranoses; Intestinal Absorption; Male; Maltose; Starch; Substrate Specificity; Sucrose | 1986 |
Molecular structure and glycosidase-inhibitory activity of nojirimycin bisulfite adduct.
Topics: 1-Deoxynojirimycin; Animals; beta-Glucosidase; Glucosamine; Glycoside Hydrolases; Molecular Conformation; Rats; Structure-Activity Relationship | 1985 |
Effect of 1-desoxynojirimycin derivatives on small intestinal disaccharidase activities and on active transport in vitro.
Topics: 1-Deoxynojirimycin; Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Biological Transport, Active; Disaccharidases; Female; Glucosamine; Imino Pyranoses; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Leucine; Methylglucosides; Rats; Rats, Inbred Strains | 1985 |
Kinetic study of the inhibition of the honeybee haemolymph apha-glucosidase in vitro by BAYe 4609, BAYg 5421 and BAYn 5595.
Topics: 1-Deoxynojirimycin; Acarbose; alpha-Glucosidases; Animals; Bees; Glucosamine; Glucosidases; Glycoside Hydrolase Inhibitors; Hemolymph; Kinetics; Oligosaccharides; Trisaccharides | 1982 |
Inhibition of N-linked complex oligosaccharide formation by 1-deoxynojirimycin, an inhibitor of processing glucosidases.
Topics: 1-Deoxynojirimycin; Glucosamine; Glucosidases; Glycoproteins; Kinetics; Oligosaccharides; Saccharomyces cerevisiae; Sucrase | 1982 |
Inhibition by nojirimycin and 1-deoxynojirimycin of microsomal glucosidases from calf liver acting on the glycoprotein oligosaccharides Glc1-3Man9GlcNAc2.
Topics: 1-Deoxynojirimycin; Animals; Anti-Bacterial Agents; Cattle; Glucosamine; Glucosidases; Glycoproteins; Kinetics; Microsomes, Liver; Oligosaccharides; Substrate Specificity | 1982 |
Effect of seven inhibitors on invertases in homogenates of human dental plaque.
Topics: 1-Deoxynojirimycin; Acarbose; beta-Fructofuranosidase; Dental Plaque; Glucosamine; Glucosidases; Glycoside Hydrolase Inhibitors; Glycoside Hydrolases; Humans; Inositol; Peptides; Piperidones; Trisaccharides | 1983 |
Inhibition by acarbose, nojirimycin and 1-deoxynojirimycin of glucosyltransferase produced by oral streptococci.
Topics: 1-Deoxynojirimycin; Acarbose; Anti-Bacterial Agents; Glucosamine; Glucosyltransferases; Humans; Kinetics; Maltose; Mouth; Oligosaccharides; Streptococcus; Streptococcus mutans; Streptococcus sanguis; Trisaccharides | 1983 |
1-deoxynojirimycin impairs oligosaccharide processing of alpha 1-proteinase inhibitor and inhibits its secretion in primary cultures of rat hepatocytes.
Topics: 1-Deoxynojirimycin; alpha 1-Antitrypsin; Animals; Blood Proteins; Cells, Cultured; Glucosamine; Glycoproteins; In Vitro Techniques; Liver; Molecular Weight; Oligosaccharides; Protease Inhibitors; Protein Processing, Post-Translational; Rats | 1983 |
Effects of the glucosidase inhibitors nojirimycin and deoxynojirimycin on the biosynthesis of membrane and secretory glycoproteins.
Topics: 1-Deoxynojirimycin; Animals; Cell Line; Glucosamine; Glucosidases; Glycoproteins; Histocompatibility Antigens Class II; HLA Antigens; HLA-DR Antigens; Humans; Immunoglobulin D; Immunoglobulin M; Membrane Proteins; Mice | 1983 |
Inhibition of N-linked oligosaccharide trimming does not interfere with surface expression of certain integral membrane proteins.
Topics: 1-Deoxynojirimycin; Animals; Cell Line; Cricetinae; Dogs; Glucosamine; Glucosidases; Glycoproteins; Hemagglutinins, Viral; HLA Antigens; Mannosidases; Membrane Proteins; Protein Processing, Post-Translational | 1984 |
Glucose removal from N-linked oligosaccharides is required for efficient maturation of certain secretory glycoproteins from the rough endoplasmic reticulum to the Golgi complex.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Endoplasmic Reticulum; Glucosamine; Glucose; Glycoproteins; Golgi Apparatus; Humans; Kinetics; Liver Neoplasms, Experimental; Protein Processing, Post-Translational; Swainsonine; Tunicamycin | 1984 |
Influence of effectors of the complex-type-oligosaccharide biosynthesis on the formation of proteokeratan sulfate in bovine cornea.
Topics: 1-Deoxynojirimycin; Alkaloids; alpha-Mannosidase; Animals; Cattle; Chondroitin Sulfate Proteoglycans; Cornea; Culture Techniques; Deoxyglucose; Glucosamine; Glycosaminoglycans; Keratan Sulfate; Lumican; Mannose; Mannosidases; Proteoglycans; Swainsonine; Swine; Tunicamycin | 1984 |
Purification by affinity chromatography of glucosidase I, an endoplasmic reticulum hydrolase involved in the processing of asparagine-linked oligosaccharides.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Asparagine; Cattle; Chemical Phenomena; Chemistry; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Glucosamine; Glucosidases; Glycoside Hydrolase Inhibitors; Hydrogen-Ion Concentration; Hydrolysis; Microsomes, Liver; Molecular Weight; Oligosaccharides; Solubility | 1984 |
Cathepsin D and beta-hexosaminidase synthesized in the presence of 1-deoxynojirimycin accumulate in the endoplasmic reticulum.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; beta-N-Acetylhexosaminidases; Cathepsin D; Cathepsins; Cell Fractionation; Cells, Cultured; Centrifugation, Density Gradient; Endoplasmic Reticulum; Fibroblasts; Glucosamine; Hexosaminidases; Humans; Kinetics | 1984 |
Characterization of Bacillus subtilis DSM704 and its production of 1-deoxynojirimycin.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Bacillus subtilis; Bacteriophages; Culture Media; Glucosamine; Kinetics; Sucrase; Transduction, Genetic | 1984 |
The effect of 1-deoxymannojirimycin on rat liver alpha-mannosidases.
Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Glucosamine; Liver; Male; Mannosidases; Rats; Rats, Inbred Strains; Solubility; Subcellular Fractions | 1984 |
The effect of deoxymannojirimycin on the processing of the influenza viral glycoproteins.
Topics: 1-Deoxynojirimycin; Alkaloids; Antiviral Agents; Chemical Phenomena; Chemistry; Glucosamine; Glycoproteins; Indolizines; Leucine; Lipids; Mannose; Oligosaccharides; Orthomyxoviridae; Protein Processing, Post-Translational; Viral Proteins | 1984 |
Processing of gPr92env, the precursor to the glycoproteins of Rous sarcoma virus: use of inhibitors of oligosaccharide trimming and glycoprotein transport.
Topics: 1-Deoxynojirimycin; Avian Sarcoma Viruses; Biological Transport, Active; Cells, Cultured; Cyclohexenes; Glucosamine; Glycoproteins; Inositol; Kinetics; Oligosaccharides; Viral Proteins; Virion | 1984 |
The formation of vesicular stomatitis virus (San Juan strain) becomes temperature-sensitive when glucose residues are retained on the oligosaccharides of the glycoprotein.
Topics: 1-Deoxynojirimycin; Acetylglucosaminidase; Alkaloids; Animals; beta-Glucosidase; Chick Embryo; Glucosamine; Glucose; Indolizines; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Membrane Glycoproteins; Mutation; Temperature; Vesicular stomatitis Indiana virus; Viral Envelope Proteins; Viral Proteins; Virion | 1984 |
Studies with inhibitors of oligosaccharide processing indicate a functional role for complex sugars in the transport and proteolysis of Friend mink cell focus-inducing murine leukemia virus envelope proteins.
Topics: 1-Deoxynojirimycin; Animals; Biological Transport; Cell Line; Cell Membrane; Glucosamine; Leukemia Virus, Murine; Mice; Mink; Oligosaccharides; Protein Processing, Post-Translational; Tunicamycin; Viral Envelope Proteins; Virion | 1984 |
An example of enzyme hysteresis. The slow and tight interaction of some fully competitive inhibitors with small intestinal sucrase.
Topics: 1-Deoxynojirimycin; Acarbose; Animals; Binding Sites; Binding, Competitive; Glucosamine; Glycoside Hydrolase Inhibitors; Intestine, Small; Kinetics; Mathematics; Protein Binding; Rabbits; Sucrase; Trisaccharides | 1981 |
[Streptococcus mutans glucosyltransferase inhibition by alpha-glucosidase inhibitors].
Topics: 1-Deoxynojirimycin; Acarbose; Binding, Competitive; Glucosamine; Glucosidases; Glucosyltransferases; Glycoside Hydrolase Inhibitors; Streptococcus mutans; Trisaccharides | 1981 |
Static and kinetic studies on the binding of Streptomyces trehalase inhibitor SGI with Rhizopus glucoamylase. Comparison with glucose and gluconolactone.
Topics: 1-Deoxynojirimycin; Glucan 1,4-alpha-Glucosidase; Gluconates; Glucosamine; Glucose; Glucosidases; Glucosides; Hydrogen-Ion Concentration; Kinetics; Lactones; Rhizopus; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Streptomyces; Thermodynamics | 1982 |
Novel glycosidase inhibitors, nojirimycin B and D-mannonic-delta-lactam. Isolation, structure determination and biological property.
Topics: 1-Deoxynojirimycin; Chemical Phenomena; Chemistry; Glucosamine; Glycoside Hydrolases; Lactams; Magnetic Resonance Spectroscopy; Molecular Conformation; Streptomyces | 1984 |
N-methyl-1-deoxynojirimycin, a novel inhibitor of glycoprotein processing, and its effect on fowl plague virus maturation.
Topics: 1-Deoxynojirimycin; Animals; Anti-Bacterial Agents; Antiviral Agents; Chick Embryo; Glucosamine; Glycoproteins; Influenza A virus; Oligosaccharides; Viral Proteins; Virion | 1983 |
Effect of inhibitors of glycosylation on proteolytic activation of avian influenza virus hemagglutinins: discrimination between tryptic cleavage and elimination of the connecting peptide.
Topics: 1-Deoxynojirimycin; Carbohydrate Metabolism; Cyclohexenes; Deoxyglucose; Glucosamine; Hemagglutinins, Viral; Influenza A virus; Inositol; Trypsin; Tunicamycin; Virion | 1984 |
Nojirimycin-a potent inhibitor of purified lysosomal alpha-glucosidase from human liver.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Glucosamine; Glucosidases; Glycoside Hydrolase Inhibitors; Humans; Hydrolysis; Kinetics; Liver; Lysosomes; Substrate Specificity | 1982 |
Role of indole-3-acetic acid, gibberellic acid and kinetin on epicotyl growth in Cicer arietinum L.
Topics: 1-Deoxynojirimycin; Clofibric Acid; Dicyclohexylcarbodiimide; Fabaceae; Gibberellins; Glucosamine; Indoleacetic Acids; Kinetin; Plant Growth Regulators; Plants, Medicinal | 1982 |
Islet glucan-1,4-alpha-glucosidase: differential influence on insulin secretion induced by glucose and isobutylmethylxanthine in mice.
Topics: 1-Deoxynojirimycin; 1-Methyl-3-isobutylxanthine; Animals; Drug Interactions; Female; Glucan 1,4-alpha-Glucosidase; Glucosamine; Glucose; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Kinetics; Lysosomes; Mice; Mice, Inbred Strains | 1993 |
The alpha-glucosidase I inhibitor castanospermine alters endothelial cell glycosylation, prevents angiogenesis, and inhibits tumor growth.
Topics: 1-Deoxynojirimycin; Animals; Cell Adhesion; Cell Aggregation; Cell Differentiation; Cell Division; Cells, Cultured; Chemotaxis; Endothelium; Glucosamine; Glycoconjugates; Glycoside Hydrolase Inhibitors; Glycosylation; Growth Inhibitors; In Vitro Techniques; Indolizines; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasms, Experimental; Neovascularization, Pathologic; Protein Processing, Post-Translational | 1995 |
Ca2+ deficiency, selective alpha-glucosidehydrolase inhibition, and insulin secretion.
Topics: 1-Deoxynojirimycin; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Dose-Response Relationship, Drug; Female; Glucosamine; Glucose; Glycoside Hydrolase Inhibitors; Imino Pyranoses; Insulin; Insulin Secretion; Islets of Langerhans; Lysosomes; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Muscular Dystrophy, Animal | 1993 |
N-containing sugars from Morus alba and their glycosidase inhibitory activities.
Topics: 1-Deoxynojirimycin; Alkaloids; Carbohydrate Sequence; Carbohydrates; Galactose; Glucosamine; Glucose; Glycoside Hydrolases; Molecular Sequence Data; Nitrogen; Plants; Sugar Alcohols; Tropanes | 1994 |
Changes in islet glucan-1,4-alpha-glucosidase activity modulate sulphonylurea-induced but not cholinergic insulin secretion.
Topics: 1-Deoxynojirimycin; Acarbose; Animals; Anti-Bacterial Agents; Blood Glucose; Carbachol; Female; Glucan 1,4-alpha-Glucosidase; Glucosamine; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Parasympathomimetics; Protein Kinase C; Sulfonylurea Compounds; Tetradecanoylphorbol Acetate; Trisaccharides | 1993 |
The effects of the intestinal glucosidase inhibitory BAY M 1099 (miglitol) on glycemic status of obese-diabetic rats.
Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Eating; Glucosamine; Glycoside Hydrolase Inhibitors; Imino Pyranoses; Male; Obesity; Rats; Rats, Inbred SHR | 1993 |
Inhibition of mouse tumor metastasis with nojirimycin-related compounds.
Topics: 1-Deoxynojirimycin; Animals; Antibiotics, Antineoplastic; Glucosamine; Glucuronidase; Glycoside Hydrolases; Lung Neoplasms; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Mice; Tumor Cells, Cultured | 1996 |
Islet acid glucan-1,4-alpha-glucosidase: a putative key enzyme in nutrient-stimulated insulin secretion.
Topics: 1-Deoxynojirimycin; Animal Nutritional Physiological Phenomena; Animals; Female; Glucan 1,4-alpha-Glucosidase; Glucosamine; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Lysosomes; Mice; Mice, Inbred Strains; Sincalide | 1996 |
Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Topics: 1-Deoxynojirimycin; Adenosine Monophosphate; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Enzyme Inhibitors; Glucosamine; Glycogen; Kinetics; Models, Molecular; Muscle, Skeletal; Phosphates; Phosphorylases; Protein Conformation; Rabbits; Tetrazoles | 1996 |
Boromycin, an anti-HIV antibiotic.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Antiviral Agents; Borates; Cell Line; Dextran Sulfate; Glucosamine; Glycoside Hydrolases; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Molecular Structure; RNA-Directed DNA Polymerase; Streptomyces | 1996 |
Modulation of islet G-proteins, alpha-glucosidehydrolase inhibition and insulin release stimulated by various secretagogues.
Topics: 1-Deoxynojirimycin; 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Cholera Toxin; Clonidine; Colforsin; Enzyme Inhibitors; Female; Glucosamine; Glucose; Glycoside Hydrolases; GTP-Binding Proteins; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mannoheptulose; Mice; Pertussis Toxin; Phosphodiesterase Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1996 |
In vitro study of the effect of miglitol on carbohydrate digestion and intestinal metabolism in normal and non-insulin-dependent diabetic rats.
Topics: 1-Deoxynojirimycin; Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucosamine; Glycoside Hydrolase Inhibitors; Imino Pyranoses; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Male; Perfusion; Rats; Rats, Wistar | 1996 |
Homonojirimycin and N-methyl-homonojirimycin inhibit N-linked oligosaccharide processing.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucosamine; Glycoproteins; Glycoside Hydrolase Inhibitors; Imino Pyranoses; Oligosaccharides; Orthomyxoviridae; Piperidines; Protein Processing, Post-Translational; Viral Envelope Proteins | 1997 |
Inhibition of glycogenolysis by a glucose analogue in the working rat heart.
Topics: 1-Deoxynojirimycin; Animals; Coronary Circulation; Depression, Chemical; Enzyme Inhibitors; Glucosamine; Glucose; Glycogen; Glycogen Debranching Enzyme System; Heart; Insulin; Lactates; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Perfusion; Rats; Rats, Wistar | 1997 |
Effect of miglitol administration to non-insulin-dependent diabetic rats.
Topics: 1-Deoxynojirimycin; Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Drug Administration Schedule; Enzyme Inhibitors; Glucosamine; Hypoglycemic Agents; Imino Pyranoses; Male; Rats; Rats, Wistar | 1998 |
A glycosidase antibody elicited against a chair-like transition state analog by in vitro immunization.
Topics: 1-Deoxynojirimycin; Antibodies, Catalytic; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolases; Glycosides; Haptens | 1998 |
Miglitol (BAY m 1099) treatment of diabetic hypothalamic-dietary obese rats improves islet response to glucose.
Topics: 1-Deoxynojirimycin; Animal Feed; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glucosamine; Glucose; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Imino Pyranoses; Insulin; Insulin Secretion; Islets of Langerhans; Obesity; Rats; Rats, Sprague-Dawley; Ventromedial Hypothalamic Nucleus | 1999 |
Isotope edited NMR studies of glycosidases: design and synthesis of a novel glycosidase inhibitor.
Topics: 1-Deoxynojirimycin; Dose-Response Relationship, Drug; Glucosamine; Glycoside Hydrolases; Kinetics; Magnetic Resonance Spectroscopy; Multigene Family; Protein Binding; Saccharomyces cerevisiae | 1999 |
Cellobiose transport by mixed ruminal bacteria from a Cow.
Topics: 1-Deoxynojirimycin; Animals; Bacteria; beta-Glucosidase; Biological Transport, Active; Cattle; Cellobiose; Enzyme Inhibitors; Glucosamine; Glucose; Kinetics; Phosphoenolpyruvate Sugar Phosphotransferase System; Rumen | 1999 |
Miglitol for type 2 diabetes mellitus.
Topics: 1-Deoxynojirimycin; Diabetes Mellitus, Type 2; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses | 1999 |
Glucose tolerance and insulin resistance in the JCR:LA-corpulent rat: effect of miglitol (Bay m1099).
Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Body Weight; Disease Models, Animal; Eating; Enzyme Inhibitors; Glucosamine; Glucose Tolerance Test; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Imino Pyranoses; Insulin; Insulin Resistance; Lipids; Male; Obesity; Postprandial Period; Rats | 1999 |
Glycoscience moves from the laboratory to the clinic.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Anti-HIV Agents; Antineoplastic Agents; Antiviral Agents; Enzyme Inhibitors; Glucosamine; HIV-1; Humans; Structure-Activity Relationship; Swainsonine | 1999 |
A novel anti-diabetic drug, miglitol, markedly reduces myocardial infarct size in rabbits.
Topics: 1-Deoxynojirimycin; Animals; Dose-Response Relationship, Drug; Glucosamine; Glycogen; Hemodynamics; Hypoglycemic Agents; Imino Pyranoses; Lactic Acid; Male; Myocardial Infarction; Myocardium; Rabbits | 1999 |
[Drug therapy of type 2 diabetes: insulin sensitizers improve results].
Topics: 1-Deoxynojirimycin; Acarbose; Diabetes Mellitus, Type 2; Diet Therapy; Diet, Diabetic; Drug Therapy, Combination; Glucosamine; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin | 1999 |
[Risk of complications in the diabetic patient. Postprandial blood glucose peaks as deciding factor].
Topics: 1-Deoxynojirimycin; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Glucosamine; Humans; Hypoglycemic Agents; Imino Pyranoses | 2000 |
Miglitol and hepatotoxicity in type 2 diabetes mellitus.
Topics: 1-Deoxynojirimycin; Acarbose; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Liver; Liver Function Tests; Transaminases | 2000 |
A new, stereocontrolled approach to iminosugar C-glycosides from L-sorbose.
Topics: 1-Deoxynojirimycin; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolases; Glycosides; Glycosyltransferases; Molecular Mimicry; Sorbose; Stereoisomerism | 2000 |
Similarity in the linear and non-linear oral absorption of drugs between human and rat.
Topics: 1-Deoxynojirimycin; Acyclovir; Administration, Oral; Animals; Chlorothiazide; Glucosamine; Humans; Imino Pyranoses; Intestinal Absorption; Propanolamines; Rats; Species Specificity | 2000 |
A new era in type 2 diabetes mellitus treatment?
Topics: 1-Deoxynojirimycin; Acarbose; Carbamates; Diabetes Mellitus, Type 2; Glucosamine; Humans; Hypoglycemic Agents; Imino Pyranoses; Multicenter Studies as Topic; Pioglitazone; Piperidines; Randomized Controlled Trials as Topic; Thiazoles; Thiazolidinediones | 2001 |
Noeuromycin, a glycosyl cation mimic that strongly inhibits glycosidases.
Topics: 1-Deoxynojirimycin; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolases; Molecular Mimicry | 2001 |
Combination of miglitol, an anti-diabetic drug, and nicorandil markedly reduces myocardial infarct size through opening the mitochondrial K(ATP) channels in rabbits.
Topics: 1-Deoxynojirimycin; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Blood Pressure; Decanoic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucosamine; Heart Rate; Hemodynamics; Hydroxy Acids; Hypoglycemic Agents; Imino Pyranoses; Male; Mitochondria, Heart; Myocardial Infarction; Nicorandil; Potassium Channels; Rabbits | 2001 |
[Alpha-glucosidase inhibitor in type 2 diabetic patients. Metabolism and body weight are favorably modified].
Topics: 1-Deoxynojirimycin; Body Weight; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Energy Metabolism; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses | 2001 |
Study of the mechanism of antiviral action of iminosugar derivatives against bovine viral diarrhea virus.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Bovine Virus Diarrhea-Mucosal Disease; Cattle; Diarrhea Viruses, Bovine Viral; Enzyme Inhibitors; Glucosamine; Virus Replication | 2001 |
Potential pharmacokinetics interference between alpha-glucosidase inhibitors and other oral antidiabetic agents.
Topics: 1-Deoxynojirimycin; Administration, Oral; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Intestinal Absorption | 2002 |
1-Aza-sugars from D-glucose. Preparation of 1-deoxy-5-dehydroxymethyl-nojirimycin, its analogues and evaluation of glycosidase inhibitory activity.
Topics: 1-Deoxynojirimycin; Aza Compounds; Enzyme Inhibitors; Glucosamine; Glucose; Glucosidases; Magnetic Resonance Spectroscopy; Spectrophotometry, Infrared | 2002 |
A general strategy for the practical synthesis of nojirimycin C-glycosides and analogues. Extension to the first reported example of an iminosugar 1-phosphonate.
Topics: 1-Deoxynojirimycin; Combinatorial Chemistry Techniques; Glucosamine; Glycosides; Imines; Molecular Mimicry; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organometallic Compounds; Oxidation-Reduction; Stereoisomerism | 2002 |
Imino sugars that are less toxic but more potent as antivirals, in vitro, compared with N-n-nonyl DNJ.
Topics: 1-Deoxynojirimycin; Alkylation; Animals; Antiviral Agents; Carbohydrates; Cell Line; Cyclization; Diarrhea Viruses, Bovine Viral; Glucosamine; Hepatitis B virus; Humans; Molecular Structure | 2002 |
[Therapy decision based on the glucose triad. Drug treatment of type 2 diabetes].
Topics: 1-Deoxynojirimycin; Acarbose; Administration, Oral; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Glucosamine; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Insulin Resistance; Insulin Secretion; Metformin; Obesity; Pioglitazone; Risk Factors; Rosiglitazone; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Time Factors | 2003 |
New synthetic approach to enantiopure bicyclic sulfonium salts: swainsonine analogues.
Topics: Catalysis; Combinatorial Chemistry Techniques; Cyclization; Glucosamine; Hydrogen-Ion Concentration; Indicators and Reagents; Indolizines; Molecular Structure; Stereoisomerism; Sulfonium Compounds; Swainsonine | 2003 |
General access to iminosugar C-glycoside building blocks by means of cross-metathesis: a gateway to glycoconjugate mimetics.
Topics: 1-Deoxynojirimycin; Alkenes; Allyl Compounds; Aminoglycosides; Catalysis; Dimerization; Glucosamine; Glycoconjugates; Imines; Molecular Mimicry; Molecular Structure; Ruthenium | 2003 |
Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors.
Topics: 1-Deoxynojirimycin; alpha-L-Fucosidase; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glucosamine; Molecular Structure | 2003 |
[Usefulness of miglitol in patients with diabetes mellitus type 2 and insufficient control of the blood glucose].
Topics: 1-Deoxynojirimycin; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Female; Glucosamine; Humans; Hyperlipidemias; Hypoglycemic Agents; Imino Pyranoses; Lipids; Male; Middle Aged; Treatment Outcome | 2004 |
Antidiabetic drug miglitol inhibits myocardial apoptosis involving decreased hydroxyl radical production and Bax expression in an ischaemia/reperfusion rabbit heart.
Topics: 1-Deoxynojirimycin; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blood Pressure; Blotting, Western; DNA Fragmentation; Electrophoresis, Agar Gel; Gentisates; Glucosamine; Heart Rate; Hemodynamics; Hydroxyl Radical; Hypoglycemic Agents; Imino Pyranoses; Immunohistochemistry; In Situ Nick-End Labeling; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rabbits; Time Factors | 2004 |
Asymmetric dihydroxylation of d-glucose derived alpha,beta-unsaturated ester: synthesis of azepane and nojirimycin analogues.
Topics: 1-Deoxynojirimycin; Azepines; Catalysis; Esters; Glucosamine; Glucose; Hydroxylation; Indicators and Reagents; Molecular Conformation; Molecular Structure; Stereoisomerism | 2004 |
Inhibition of glucosylceramide synthase does not reverse drug resistance in cancer cells.
Topics: 1-Deoxynojirimycin; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Ceramides; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Flow Cytometry; Glucosamine; Glucosylceramides; Glucosyltransferases; Glycolipids; Humans; Imino Sugars; Lipids; Morpholines; Quinolines; Time Factors; Vinblastine | 2004 |
Discovery of picomolar slow tight-binding inhibitors of alpha-fucosidase.
Topics: 1-Deoxynojirimycin; alpha-L-Fucosidase; Combinatorial Chemistry Techniques; Corynebacterium; Enzyme Inhibitors; Glucosamine; Kinetics; Molecular Structure; Spectrometry, Fluorescence | 2004 |
Simple syntheses of 4-O-glucosylated 1-deoxynojirimycins from maltose and cellobiose.
Topics: Cellobiose; Glucosamine; Glucose; Glycoside Hydrolase Inhibitors; Glycosylation; Maltose | 2004 |
A Madagascar Sponge Batzella sp. as a source of alkylated iminosugars.
Topics: 1-Deoxynojirimycin; Amino Sugars; Animals; Anti-Bacterial Agents; Glucosamine; Madagascar; Microbial Sensitivity Tests; Molecular Structure; Porifera; Pyridinium Compounds; Staphylococcus epidermidis | 2005 |
[Treatment of type 2 diabetes mellitus with the alpha-glucosidase inhibitor Miglitol in the doctor's office].
Topics: 1-Deoxynojirimycin; Adult; Age Factors; Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 2; Family Practice; Feasibility Studies; Female; Follow-Up Studies; Glucosamine; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Imino Pyranoses; Internal Medicine; Male; Middle Aged; Patient Compliance; Risk Factors; Sex Factors; Time Factors; Treatment Outcome; Weight Loss | 2000 |
[The alpha-glucosidase inhibitor miglitol for the treatment of type 2 diabetes mellitus in the doctor's office].
Topics: 1-Deoxynojirimycin; Adult; Aged; Aged, 80 and over; Blood Glucose; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Female; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Male; Middle Aged; Safety; Time Factors; Triglycerides | 2001 |
Aglycon specificity profiling of alpha-glucosidases using synthetic probes.
Topics: 1-Deoxynojirimycin; Animals; Drug Design; Geobacillus stearothermophilus; Glucosamine; Glycoside Hydrolase Inhibitors; Heptoses; Hydrogen Bonding; Microbial Sensitivity Tests; Molecular Conformation; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2005 |
General synthesis and biological evaluation of alpha-1-C-substituted derivatives of fagomine (2-deoxynojirimycin-alpha-C-glycosides).
Topics: 1-Deoxynojirimycin; Animals; Aziridines; Cattle; Cyclization; Glucosamine; Glycoside Hydrolases; Glycosides; Humans; Imino Pyranoses; Inhibitory Concentration 50; Molecular Structure; Oxidation-Reduction; Piperidines; Rats; Structure-Activity Relationship | 2005 |
The anti-diabetic drug miglitol is protective against anginal ischaemia through a mechanism independent of regional myocardial blood flow in the dog.
Topics: 1-Deoxynojirimycin; Angina Pectoris; Animals; Blood Glucose; Blood Pressure; Coronary Circulation; Dogs; Glucosamine; Heart Rate; Hypoglycemic Agents; Imino Pyranoses; Lactates; Male; Myocardial Ischemia; Myocardium | 2005 |
Asymmetric synthesis of the L-fuco-nojirimycin, a nanomolar alpha-L-fucosidase inhibitor.
Topics: 1-Deoxynojirimycin; alpha-L-Fucosidase; Animals; Cattle; Enzyme Inhibitors; Glucosamine; Kidney; Molecular Structure; Stereoisomerism | 2006 |
Isolation and structure assignment of an iminotetrasaccharide from a cultured filamentous cyanobacterium Anabaena sp.
Topics: 1-Deoxynojirimycin; Anabaena; Australia; Crystallography, X-Ray; Enzyme Inhibitors; Glucosamine; Glucuronidase; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oligosaccharides | 2006 |
[Pharmacokinetic, pharmacological, and clinical profile of miglitol (SEIBULE), a novel alpha-glucosidase inhibitor].
Topics: 1-Deoxynojirimycin; Animals; Diabetes Mellitus, Type 2; Dogs; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Rats | 2006 |
Discovery of different types of inhibition between the human and thermotoga maritima alpha-fucosidases by fuconojirimycin-based derivatives.
Topics: 1-Deoxynojirimycin; alpha-L-Fucosidase; Base Sequence; Crystallography, X-Ray; DNA Primers; Enzyme Inhibitors; Glucosamine; Humans; Models, Molecular; Molecular Structure; Thermotoga maritima | 2006 |
Synthesis and biological evaluation of glycosidase inhibitors: gem-difluoromethylenated nojirimycin analogues.
Topics: 1-Deoxynojirimycin; Glucosamine; Glycoside Hydrolases; Hydrogen-Ion Concentration; Imino Pyranoses; Structure-Activity Relationship | 2006 |
1,3-Dideoxynojirimycin-3-yl glycosides of beta-(1-->3)- and beta-(1-->6)-linked gluco-oligosaccharides.
Topics: 1-Deoxynojirimycin; Acetamides; Carbohydrate Conformation; Carbohydrate Sequence; Chloroacetates; Glucosamine; Glycosides; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Oligosaccharides; Trichloroacetic Acid | 2006 |
Liquid chromatographic tandem mass spectrometry method for the quantification of miglitol in human plasma.
Topics: 1-Deoxynojirimycin; Biological Availability; Chromatography, Liquid; Glucosamine; Half-Life; Humans; Hypoglycemic Agents; Imino Pyranoses; Magnetic Resonance Spectroscopy; Mass Spectrometry; Reproducibility of Results; Therapeutic Equivalency | 2006 |
Alpha-1-C-octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease.
Topics: 1-Deoxynojirimycin; Cell Line; Dose-Response Relationship, Drug; Gaucher Disease; Glucosamine; Glucosylceramidase; Humans; Molecular Chaperones; Molecular Mimicry; Structure-Activity Relationship | 2006 |
Reduced inflammatory potential of peritoneal macrophages recruited in mice pretreated with a glycolipid synthesis inhibitor.
Topics: 1-Deoxynojirimycin; Animals; Cell Survival; Cytokines; Enzyme Inhibitors; Glucosamine; Glucosyltransferases; Glycosphingolipids; Immunity, Innate; Macrophages, Peritoneal; Mice; Mice, Inbred C3H | 2006 |
Reduction of the infectivity of hepatitis C virus pseudoparticles by incorporation of misfolded glycoproteins induced by glucosidase inhibitors.
Topics: 1-Deoxynojirimycin; Antiviral Agents; Cell Line; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Glycosylation; Hepacivirus; Humans; Luciferases; Microscopy, Immunoelectron; Protein Binding; Protein Folding; Viral Envelope Proteins; Virus Replication | 2007 |
Iminosugars in combination with interferon and ribavirin permanently eradicate noncytopathic bovine viral diarrhea virus from persistently infected cells.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Cell Line; Diarrhea Viruses, Bovine Viral; Dose-Response Relationship, Drug; Glucosamine; Interferons; Molecular Structure; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA, Viral; Time Factors | 2008 |
Multivalent iminosugars to modulate affinity and selectivity for glycosidases.
Topics: 1-Deoxynojirimycin; Glucosamine; Glycoside Hydrolases; Imino Sugars; Structure-Activity Relationship | 2009 |
Deoxynojirimycin enhanced the transglycosylation activity of a glycosidase from the China white jade snail.
Topics: 1-Deoxynojirimycin; Animals; Butanols; Cellobiose; Glucosamine; Glycoside Hydrolases; Glycosides; Glycosylation; Hydrolysis; Kinetics; Nonlinear Dynamics; Regression Analysis; Snails; Substrate Specificity | 2009 |
Structural determinants of product specificity of sucrose isomerases.
Topics: 1-Deoxynojirimycin; Amino Acid Motifs; Amino Acid Sequence; Arginine; Catalytic Domain; Crystallography, X-Ray; Gammaproteobacteria; Glucosamine; Glucosyltransferases; Intramolecular Transferases; Isomaltose; Macromolecular Substances; Models, Molecular; Protein Conformation; Static Electricity; Substrate Specificity; Sweetening Agents | 2009 |
Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2.
Topics: 1-Deoxynojirimycin; Amino Acid Sequence; Amino Acid Substitution; Asparagine; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Glucosamine; Glycosylation; Humans; Indolizines; Leupeptins; Macrolides; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Sequence Data; Neoplasm Proteins; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Proteasome Endopeptidase Complex; Sequence Alignment; Tunicamycin; Ubiquitin | 2009 |
A membrane-bound trehalase from Chironomus riparius larvae: purification and sensitivity to inhibition.
Topics: 1-Deoxynojirimycin; Alkaloids; Animals; Cell Membrane; Chironomidae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolases; Kinetics; Larva; Membrane Proteins; Models, Biological; Pyrroles; Substrate Specificity; Trehalase | 2010 |
Deoxynojirimycin and its hexosaminyl derivatives bind to natural killer cell receptors rNKR-P1A and hCD69.
Topics: 1-Deoxynojirimycin; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Disaccharides; Glucosamine; Glycosylation; Hexosamines; Humans; Lectins, C-Type; Monosaccharides; Oxidation-Reduction; Rats; Receptors, Immunologic | 2010 |
Probing the active-site requirements of human intestinal N-terminal maltase-glucoamylase: Synthesis and enzyme inhibitory activities of a six-membered ring nitrogen analogue of kotalanol and its de-O-sulfonated derivative.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Catalytic Domain; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Intestines; Kinetics; Monosaccharides; Nitrogen; Structure-Activity Relationship; Sulfates; Sulfones | 2010 |
Intestinal glucose-induced calcium-calmodulin kinase signaling in the gut-brain axis in awake rats.
Topics: 1-Deoxynojirimycin; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Consciousness; Enterochromaffin Cells; Gastrointestinal Tract; Glucosamine; Glucose; Intestinal Mucosa; Male; Models, Animal; Myenteric Plexus; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Signal Transduction; Sodium-Glucose Transport Proteins | 2011 |
Identification of a gene cluster that initiates azasugar biosynthesis in Bacillus amyloliquefaciens.
Topics: 1-Deoxynojirimycin; Bacillus; Gene Knockout Techniques; Glucosamine; Imino Sugars; Multigene Family | 2011 |
Solution and gas-phase H/D exchange of protein-small-molecule complexes: Cex and its inhibitors.
Topics: 1-Deoxynojirimycin; Amino Acid Sequence; Deuterium Exchange Measurement; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolases; Imino Pyranoses; Mass Spectrometry; Molecular Sequence Data; Protein Binding | 2012 |
Screening α-glucosidase inhibitors from mulberry extracts via DOSY and relaxation-edited NNR.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Ligands; Magnetic Resonance Spectroscopy; Morus; Plant Extracts; Plant Leaves | 2012 |
Abrogating effect of N-linked carbohydrate modifiers on the stem cell factor and endothelin-1-stimulated epidermal pigmentation in human epidermal equivalents.
Topics: 1-Deoxynojirimycin; Carbohydrates; Cell Survival; Cells, Cultured; Cytokines; Endothelin-1; Epidermis; Glucosamine; Humans; Keratinocytes; Lentigo; Melanocytes; Melanosomes; Monensin; Pigmentation; S100 Proteins; Stem Cell Factor; Sunlight; Time Factors; Ultraviolet Rays | 2013 |
N-Alkyldeoxynojirimycin derivatives with novel terminal tertiary amide substitution for treatment of bovine viral diarrhea virus (BVDV), Dengue, and Tacaribe virus infections.
Topics: 1-Deoxynojirimycin; Amides; Animals; Antiviral Agents; Cell Line; Cell Survival; Cricetinae; Defective Viruses; Dengue; Diarrhea Viruses, Bovine Viral; Dose-Response Relationship, Drug; Glucosamine; Humans; Molecular Structure; Structure-Activity Relationship | 2013 |
Novel imino sugar α-glucosidase inhibitors as antiviral compounds.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Antiviral Agents; Cattle; Cell Survival; Click Chemistry; Diarrhea Viruses, Bovine Viral; Dogs; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolase Inhibitors; Glycosylation; Hepacivirus; Imino Sugars; Madin Darby Canine Kidney Cells; Viral Envelope Proteins; Virus Replication | 2013 |
Design and synthesis of N-alkyldeoxynojirimycin derivatives with improved metabolic stability as inhibitors of BVDV and Tacaribe virus.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Arenaviruses, New World; Diarrhea Viruses, Bovine Viral; Drug Design; Glucosamine; Humans; Mice; Microsomes, Liver; Oxazolidinones; Rats; Sulfonamides; Urea; Virus Replication | 2013 |
Glycosylation of tyrosinase is a determinant of melanin production in cultured melanoma cells.
Topics: 1-Deoxynojirimycin; Antibodies; Cell Line, Tumor; Glucosamine; Glycosylation; HSP70 Heat-Shock Proteins; Humans; Immunoprecipitation; Melanins; Melanoma; Molecular Weight; Monophenol Monooxygenase; Protein Binding | 2013 |
Inhibition of major virulence pathways of Streptococcus mutans by quercitrin and deoxynojirimycin: a synergistic approach of infection control.
Topics: 1-Deoxynojirimycin; Anti-Bacterial Agents; Antigens, Bacterial; Bacterial Adhesion; Biofilms; Drug Synergism; Extracellular Space; Gene Expression Regulation, Bacterial; Glucans; Glucosamine; Hydrophobic and Hydrophilic Interactions; Infection Control; Microbial Sensitivity Tests; Microbial Viability; Polysaccharides, Bacterial; Quercetin; Streptococcus mutans; Stress, Physiological; Virulence | 2014 |
Synthetic 1-deoxynojirimycin N-substituted peptides offer prolonged disruption to N-linked glycan processing.
Topics: alpha-Glucosidases; Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Cricetulus; Endoplasmic Reticulum; Enzyme Inhibitors; Glucosamine; Glycosylation; Imino Sugars; Nitrogen; Peptides; Polysaccharides; Protein Binding | 2014 |
Hypoglycemic effect of deoxynojirimycin-polysaccharide on high fat diet and streptozotocin-induced diabetic mice via regulation of hepatic glucose metabolism.
Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fructose-Bisphosphatase; Glucokinase; Glucosamine; Glucose-6-Phosphatase; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Mice; Mice, Inbred ICR; Phosphoenolpyruvate Carboxykinase (ATP); Phosphofructokinase-1, Liver Type; Pyruvate Carboxylase; Pyruvate Decarboxylase; Random Allocation | 2015 |
Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors.
Topics: 1-Deoxynojirimycin; Alkaloids; Castanospermum; Enzyme Inhibitors; Glucosamine; Glycoside Hydrolases; Hypoglycemic Agents; Imino Sugars; Indolizines; Piperidines; Stereoisomerism; Structure-Activity Relationship | 2015 |
A fluorescence study of isofagomine protonation in β-glucosidase.
Topics: beta-Glucosidase; Chemistry Techniques, Synthetic; Enzyme Inhibitors; Glucosamine; Hydrogen-Ion Concentration; Imino Pyranoses; Kinetics; Protons; Prunus dulcis; Spectrometry, Fluorescence; Structure-Activity Relationship | 2015 |
Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors.
Topics: 1-Deoxynojirimycin; Ceramides; Enzyme Inhibitors; Glucosamine; Glucosyltransferases; Humans; Inhibitory Concentration 50; Isoenzymes; Protein Binding; Structure-Activity Relationship | 2015 |
Evaluation of monovalent and multivalent iminosugars to modulate Candida albicans β-1,2-mannosyltransferase activities.
Topics: 1-Deoxynojirimycin; Candida albicans; Cell Wall; Cloning, Molecular; Enzyme Assays; Enzyme Inhibitors; Fungal Proteins; Gene Expression; Glucosamine; Imino Sugars; Kinetics; Mannosides; Mannosyltransferases; Pichia; Recombinant Proteins; Substrate Specificity | 2016 |
Selenoureido-iminosugars: A new family of multitarget drugs.
Topics: 1-Deoxynojirimycin; Acetylcholinesterase; Alkylation; Cellulases; Drug Design; Gaucher Disease; Glucosamine; Glutathione Peroxidase; Humans; Imino Sugars; Organoselenium Compounds | 2016 |
Three-step synthesis of l-ido-1-deoxynojirimycin derivatives by reductive amination in water, "borrowing hydrogen" under neat conditions and deprotection.
Topics: 1-Deoxynojirimycin; Amination; Catalysis; Chemistry Techniques, Synthetic; Glucosamine; Hydrogen; Iridium; Oxidation-Reduction; Water | 2016 |
Synthesis and characterization of novel, conjugated, fluorescent DNJ derivatives for α-glucosidase recognition.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Cell Membrane; Dose-Response Relationship, Drug; Fluorescent Dyes; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2017 |
Synthesis of Natural O-Linked Carba-Disaccharides, (+)- and (-)-Pericosine E, and Their Analogues as α-Glucosidase Inhibitors.
Topics: 1-Deoxynojirimycin; Alcohols; alpha-Glucosidases; Ascomycota; Chlorohydrins; Disaccharides; Epoxy Compounds; Glucosamine; Glycoside Hydrolase Inhibitors; Shikimic Acid; Stereoisomerism; Yeasts | 2017 |
Probing the Inhibitor versus Chaperone Properties of sp²-Iminosugars towards Human β-Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease.
Topics: 1-Deoxynojirimycin; Enzyme Inhibitors; Fibroblasts; Gaucher Disease; Glucosamine; Glucosylceramidase; Humans; Imino Sugars; Molecular Chaperones; Mutation | 2018 |
Determination of 1-Deoxynojirimycin by a developed and validated HPLC-FLD method and assessment of In-vitro antioxidant, α-Amylase and α-Glucosidase inhibitory activity in mulberry varieties from Turkey.
Topics: 1-Deoxynojirimycin; alpha-Amylases; Antioxidants; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Fluorenes; Gas Chromatography-Mass Spectrometry; Glucosamine; Glycoside Hydrolase Inhibitors; Limit of Detection; Morus; Plant Leaves; Reproducibility of Results; Turkey | 2019 |
2-Phenylquinoline-Sugar Hybrids as Photoswitchable α-Glucosidase Inhibitors.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Glucosamine; Glycoside Hydrolase Inhibitors; Monosaccharides; Photolysis; Quinolines; Ultraviolet Rays | 2019 |
N,O-Dialkyl deoxynojirimycin derivatives as CERT START domain ligands.
Topics: 1-Deoxynojirimycin; Binding Sites; Ceramides; Glucosamine; Glycoside Hydrolases; Humans; Ligands; Molecular Docking Simulation; Protein Binding; Protein Domains; Protein Serine-Threonine Kinases; Stereoisomerism; Thermodynamics | 2020 |
Supramolecular azasugar clusters based on an amphiphilic fatty-acid-deoxynojirimycin derivative as multivalent glycosidase inhibitors.
Topics: 1-Deoxynojirimycin; alpha-Mannosidase; Animals; Blood Glucose; Cell Survival; Enzyme Inhibitors; Fatty Acids; Glucosamine; Glucose Tolerance Test; Hydrogen-Ion Concentration; Hypoglycemic Agents; Maltose; Mice | 2019 |
Synthesis, self-assembly behaviours and multivalent glycosidase inhibition effects of a deoxynojirimycin modified perylene bisimide derivative.
Topics: 1-Deoxynojirimycin; Animals; Glucosamine; Glycoside Hydrolases; Humans; Imides; Mice; Perylene | 2019 |
Strategy for Designing Selective Lysosomal Acid α-Glucosidase Inhibitors: Binding Orientation and Influence on Selectivity.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Antiviral Agents; Drug Design; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Imino Sugars; Molecular Docking Simulation | 2020 |
Synthesis,
Topics: 1-Deoxynojirimycin; Acarbose; alpha-Glucosidases; Benzylidene Compounds; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2020 |
Genome analysis of 1-deoxynojirimycin (1-DNJ)-producing Bacillus velezensis K26 and distribution of Bacillus sp. harboring a 1-DNJ biosynthetic gene cluster.
Topics: 1-Deoxynojirimycin; Bacillus; Genes, Bacterial; Glucosamine; Multigene Family; Phylogeny; Sequence Homology | 2021 |
Positional Isomeric Effects on the Optical Properties, Multivalent Glycosidase Inhibition Effect, and Hypoglycemic Effect of Perylene Bisimide-deoxynojirimycin Conjugates.
Topics: Administration, Oral; Animals; Binding Sites; Blood Glucose; Glucosamine; Glycoside Hydrolases; Hydrogen Bonding; Hypoglycemic Agents; Imides; Isomerism; Kinetics; Mice; Molecular Conformation; Molecular Docking Simulation; Perylene; Protein Binding; Thermodynamics | 2021 |