Compounds > 1-deoxynojirimycin
Page last updated: 2024-08-23

1-deoxynojirimycin and adamantane

1-deoxynojirimycin has been researched along with adamantane in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (40.00)29.6817
2010's8 (53.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Aerts, JM; Boon, L; Bullens, D; Ceuppens, JL; Geboes, K; Kasran, A; Maerten, P; Rutgeerts, P; Shen, C; Van Assche, G1
Aerts, JM; Aten, J; Dubbelhuis, PF; Grefhorst, A; Kuipers, F; O'Rahilly, S; Ottenhoff, R; Overkleeft, HS; Powlson, AS; Serlie, MJ; Sethi, JK; van Eijk, M; Wennekes, T1
Aerts, JM; Bijl, N; Boot, RG; Groen, AK; Houten, S; Scheij, S1
Aerts, JM; Bijl, N; Boot, RG; Groen, AK; Ottenhoff, R; Scheij, S; Sokolovic, M; Triantis, V; van Eijk, M; van Roomen, CP1
Aerts, JM; Arbeeny, C; Aten, J; Bijl, N; Dubbelhuis, PF; Ghauharali-van der Vlugt, K; Groen, AK; Ottenhoff, R; Overkleeft, HS; Seeman, I; van Eijk, M; van Roomen, CP1
Aerts, JM; Aten, J; Bijl, N; Boot, RG; Claessen, N; Groen, AK; Langeveld, M; Moerland, PD; Ottenhoff, R; Sokolović, M; van Eijk, M; van Roomen, CP; Vrins, C1
Aerts, JM; Bietrix, F; Groen, AK; Lombardo, E; Ottenhoff, R; Rensen, PC; van Roomen, CP; Verhoeven, AJ; Vos, M1
Aerts, JM; Bijl, N; Bijland, S; Groen, AK; Houben-Weerts, JH; Houten, SM; Langeveld, M; Ottenhoff, R; Romijn, JA; van den Berg, SA; van Dijk, KW; van Roomen, CP; Voshol, PJ1
Aerts, JM; Aten, J; Bietrix, FM; Bijl, N; Boot, RG; Dekker, N; Groen, AK; Groener, J; Langeveld, M; Lombardo, E; Ottenhoff, R; Overkleeft, HS; Serlie, M; van Eijk, M; van Roomen, C; Wennekes, T1
Aerts, JM; Aten, J; Bietrix, F; Groen, AK; Kuiper, J; Lombardo, E; Ottenhoff, R; Overkleeft, HS; van Eijk, M; van Puijvelde, GH; van Roomen, CP; Verhoeven, AJ1
Barragán Monasterio, M; Berniakovich, I; Eguizábal, C; García Fernández, JM; González, F; Gort, L; Izpisua Belmonte, JC; Matalonga, L; Ortiz Mellet, C; Ribes, A; Tiscornia, G; Veiga, A; Vivas, EL1
Abe, H; Fujitani, Y; Hara, A; Ishibashi, K; Kanazawa, A; Kawamori, R; Komiya, K; Ogihara, T; Tamaki, M; Uchida, T; Watada, H1
Aoki, K; Kamiko, K; Kamiyama, H; Masuda, K; Noguchi, Y; Tajima, K; Terauchi, Y1
Aerts, JMFG; Boot, R; Foppen, E; Herrera Moro Chao, D; Jansen, K; Kalsbeek, A; Kooijman, S; Marques, AR; Mergen, C; Mirzaian, M; Ottenhoff, R; Overkleeft, H; Parlevliet, ET; Rensen, PCN; Scheij, S; Seeley, RJ; Tschöp, MH; van Eijk, M; van Roomen, C; Verhoek, M; Wang, D; Wang, Y; Yi, CX1
Iftikhar, M; Lu, Y; Zhou, M1

Reviews

2 review(s) available for 1-deoxynojirimycin and adamantane

ArticleYear
Glycosphingolipids and insulin resistance.
    Advances in experimental medicine and biology, 2011, Volume: 721

    Topics: 1-Deoxynojirimycin; Adamantane; Animals; Cardiovascular Diseases; Ceramides; Diabetes Mellitus, Type 2; Dioxanes; Disease Models, Animal; Fatty Acids; Fatty Liver; Gaucher Disease; Glucosyltransferases; Glycosphingolipids; Humans; Insulin Resistance; Metabolic Syndrome; Mice; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Pyrrolidines; Receptor, Insulin; Signal Transduction

2011
An overview of therapeutic potential of N-alkylated 1-deoxynojirimycin congeners.
    Carbohydrate research, 2021, Volume: 504

    Topics: 1-Deoxynojirimycin; Adamantane; Animals; Diabetes Mellitus, Type 2; Female; Swine

2021

Other Studies

13 other study(ies) available for 1-deoxynojirimycin and adamantane

ArticleYear
Inhibition of glycolipid biosynthesis by N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin protects against the inflammatory response in hapten-induced colitis.
    International immunopharmacology, 2004, Volume: 4, Issue:7

    Topics: 1-Deoxynojirimycin; Adamantane; Animals; Anti-Inflammatory Agents; Antibodies; Body Weight; Colitis; Colon; Disease Models, Animal; Enzyme Inhibitors; Glycolipids; Haptens; Immunoglobulin G; Immunosuppressive Agents; Interferon-gamma; Interleukin-18; Male; Mice; Mice, Inbred C57BL; Oxazolone; Peroxidase; Trinitrobenzenesulfonic Acid

2004
Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.
    Diabetes, 2007, Volume: 56, Issue:5

    Topics: 1-Deoxynojirimycin; 3T3 Cells; Adamantane; Adipocytes; Animals; Ceramides; Enzyme Inhibitors; Glucose Intolerance; Glucosylceramides; Glucosyltransferases; Glycosphingolipids; Humans; Insulin; Liver; Mice; Mice, Inbred C57BL; Mice, Obese; Pancreas; Signal Transduction

2007
The glucosylceramide synthase inhibitor N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin induces sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in HepG2 cells.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 326, Issue:3

    Topics: 1-Deoxynojirimycin; Adamantane; Cell Line; Cholesterol; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glucosyltransferases; Humans; Sterol Regulatory Element Binding Proteins

2008
Reduction of glycosphingolipid biosynthesis stimulates biliary lipid secretion in mice.
    Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:2

    Topics: 1-Deoxynojirimycin; Adamantane; Animals; Bile; Cell Line, Tumor; Cells, Cultured; Cholesterol; Cholesterol, HDL; Gallbladder; Gangliosides; Glycosphingolipids; Humans; Lipid Metabolism; Lipoproteins, HDL; Liver Neoplasms; Mice; Mice, Inbred C57BL; RNA, Messenger; Signal Transduction; Triglycerides

2009
Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation.
    PloS one, 2009, Volume: 4, Issue:3

    Topics: 1-Deoxynojirimycin; Adamantane; Adipogenesis; Adiponectin; Adipose Tissue; Animals; Chemokine CCL2; Glucose; Glycosphingolipids; Homeostasis; Inflammation; Insulin Resistance; Macrophages; Mice; Mice, Inbred C57BL; Mice, Obese; Signal Transduction

2009
Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice.
    Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:5

    Topics: 1-Deoxynojirimycin; Adamantane; Animals; Disease Models, Animal; Fatty Liver; Glucose; Glycosphingolipids; Homeostasis; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Triglycerides

2009
Inhibition of glycosphingolipid synthesis induces a profound reduction of plasma cholesterol and inhibits atherosclerosis development in APOE*3 Leiden and low-density lipoprotein receptor-/- mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:5

    Topics: 1-Deoxynojirimycin; Adamantane; Animals; Apolipoproteins E; Atherosclerosis; Bile; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Feces; Female; Glucosyltransferases; Glycosphingolipids; Hyperlipidemias; Kinetics; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mutation; Receptors, LDL

2010
Treatment of genetically obese mice with the iminosugar N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin reduces body weight by decreasing food intake and increasing fat oxidation.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:1

    Topics: 1-Deoxynojirimycin; Adamantane; Adipose Tissue; Animals; Body Weight; Carbohydrate Metabolism; Carnitine O-Palmitoyltransferase; Eating; Ghrelin; Glucose; Imino Sugars; Liver; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Oxidation-Reduction; Peptide YY; Triglycerides; Up-Regulation; Weight Gain

2012
Correction of liver steatosis by a hydrophobic iminosugar modulating glycosphingolipids metabolism.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: 1-Deoxynojirimycin; Actins; Adamantane; Animals; Apolipoprotein E3; Cell Membrane; Diet, High-Fat; Dose-Response Relationship, Drug; Fatty Acids; Fatty Liver; Female; Gene Expression; Glycosphingolipids; Humans; Hydrophobic and Hydrophilic Interactions; Imino Sugars; Immunohistochemistry; Insulin; Lipid Metabolism; Liver; Mice; Mice, Knockout; Mice, Transgenic; Muscle, Smooth; Oxidation-Reduction; Receptors, LDL

2012
Neuronopathic Gaucher's disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds.
    Human molecular genetics, 2013, Feb-15, Volume: 22, Issue:4

    Topics: 1-Deoxynojirimycin; Adamantane; Antigens, Differentiation; Base Sequence; Cell Differentiation; Cells, Cultured; DNA Mutational Analysis; Dopaminergic Neurons; Drug Evaluation, Preclinical; Enzyme Stability; Gaucher Disease; Gene Expression; Glucosylceramidase; Humans; Induced Pluripotent Stem Cells; Kruppel-Like Factor 4; Lysosomes; Macrophages; Oligonucleotide Array Sequence Analysis; Protein Transport; Small Molecule Libraries; Transcriptome

2013
Beneficial effects of vildagliptin combined with miglitol on glucose tolerance and islet morphology in diet-controlled db/db mice.
    Biochemical and biophysical research communications, 2013, Nov-01, Volume: 440, Issue:4

    Topics: 1-Deoxynojirimycin; Adamantane; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Glucose Tolerance Test; Hypoglycemic Agents; Islets of Langerhans; Male; Mice; Mice, Inbred Strains; Nitriles; Pyrrolidines; Vildagliptin

2013
Effects of miglitol, vildagliptin, or their combination on serum insulin and peptide YY levels and plasma glucose, cholecystokinin, ghrelin, and obestatin levels.
    Endocrine journal, 2014, Volume: 61, Issue:3

    Topics: 1-Deoxynojirimycin; Adamantane; Adult; Blood Glucose; Cholecystokinin; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Ghrelin; Humans; Insulin; Male; Middle Aged; Nitriles; Peptide YY; Pyrrolidines; Vildagliptin

2014
The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1.
    Diabetes, 2019, Volume: 68, Issue:12

    Topics: 1-Deoxynojirimycin; Adamantane; Adipose Tissue, Brown; Animals; Brain; Glucagon-Like Peptide 1; Glucose; Male; Mice; Mice, Inbred C57BL; Obesity; Rats; Rats, Wistar; Satiation; Signal Transduction

2019