1-deazaadenosine has been researched along with tubercidin in 11 studies
| Studies (1-deazaadenosine) | Trials (1-deazaadenosine) | Recent Studies (post-2010) (1-deazaadenosine) | Studies (tubercidin) | Trials (tubercidin) | Recent Studies (post-2010) (tubercidin) |
|---|---|---|---|---|---|
| 21 | 0 | 4 | 743 | 1 | 114 |
| Protein | Taxonomy | 1-deazaadenosine (IC50) | tubercidin (IC50) |
|---|---|---|---|
| Adenosine kinase | Homo sapiens (human) | 10 | |
| Programmed cell death protein 4 | Homo sapiens (human) | 0.88 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cristalli, G; Eleuteri, A; Franchetti, P; Grifantini, M; Lupidi, G; Vittori, S | 1 |
| Frieden, C; Kurz, LC; Moix, L; Riley, MC | 1 |
| Balduini, W; Cantoni, O; Cattabeni, F; Cristalli, G; Grifantini, M; Sestili, P | 1 |
| Cristalli, G; Franchetti, P; Grifantini, M; Klotz, KN; Lohse, MJ; Vittori, S | 1 |
| Bordoni, T; Cristalli, G; Franchetti, P; Geroni, C; Grifantini, M; Vittori, S | 1 |
| Quiocho, FA; Wilson, DK | 1 |
| Beigelman, L; Burgin, A; Debelak, H; Seela, F; Usman, N | 1 |
| Kalinichenko, EN; Mikhailopulo, IA; Player, MR; Podkopaeva, TL; Seela, F; Torrence, PF | 1 |
| Costanzi, S; Cristalli, G; IJzerman, AP; Kunzel, JK; Lorenzen, A; Stannek, C; Vittori, S; Volpini, R | 1 |
| Britt, BM; Castro, C | 1 |
| Kinoshita, T; Nakanishi, I; Tada, T | 1 |
11 other study(ies) available for 1-deazaadenosine and tubercidin
| Article | Year |
|---|---|
Adenosine deaminase inhibitors: synthesis and structure-activity relationships of imidazole analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Intestines; Molecular Structure; Structure-Activity Relationship; Tubercidin | 1991 |
The rate of formation of transition-state analogues in the active site of adenosine deaminase is encounter-controlled: implications for the mechanism.
Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Binding Sites; Catalysis; Cattle; Circular Dichroism; Intestines; Purine Nucleosides; Ribonucleosides; Solvents; Spectrophotometry, Ultraviolet; Tubercidin | 1992 |
Inhibition of nucleic acids and protein synthesis by deazaadenosine derivatives: a study on structure-activity relationships.
Topics: Animals; Cattle; Cell Line; DNA; Dose-Response Relationship, Drug; Haplorhini; Hydrogen Peroxide; Kidney; Protein Biosynthesis; Ribonucleosides; RNA; Structure-Activity Relationship; Tubercidin | 1985 |
Adenosine receptor agonists: synthesis and biological evaluation of 1-deaza analogues of adenosine derivatives.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Aminoglycosides; Animals; Anti-Bacterial Agents; Cattle; Humans; Rats; Receptors, Purinergic; Structure-Activity Relationship; Tubercidin | 1988 |
Improved synthesis and antitumor activity of 1-deazaadenosine.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Female; HeLa Cells; Humans; Leukemia L1210; Leukemia P388; Mice; Ribonucleosides; Tubercidin; Uterine Cervical Neoplasms | 1987 |
A pre-transition-state mimic of an enzyme: X-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water.
Topics: Adenosine Deaminase; Animals; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallization; Escherichia coli; Hydrogen Bonding; Hydrogen-Ion Concentration; Mice; Molecular Structure; Tubercidin; Water; X-Ray Diffraction; Zinc | 1993 |
1-Deazaadenosine: synthesis and activity of base-modified hammerhead ribozymes.
Topics: Base Composition; Base Sequence; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Nucleic Acid Conformation; Oligoribonucleotides; RNA, Catalytic; Tubercidin | 1998 |
Dissection of the roles of adenine ring nitrogen (N-1) and exocyclic amino (N-6) moieties in the interaction of 2-5A with RNase L.
Topics: Adenine Nucleotides; Adenosine; Endoribonucleases; Enzyme Activation; Humans; Molecular Structure; Oligoribonucleotides; Recombinant Proteins; RNA-Binding Proteins; Tubercidin | 1998 |
N-cycloalkyl derivatives of adenosine and 1-deazaadenosine as agonists and partial agonists of the A(1) adenosine receptor.
Topics: Adenosine; Animals; Brain; Guanosine 5'-O-(3-Thiotriphosphate); Magnetic Resonance Spectroscopy; Phenethylamines; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Tubercidin; Xanthines | 2000 |
Binding thermodynamics of the transition state analogue coformycin and of the ground state analogue 1-deazaadenosine to bovine adenosine deaminase.
Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Binding Sites; Cattle; Coformycin; Enzyme Inhibitors; Mathematics; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Temperature; Thermodynamics; Tubercidin | 2001 |
Conformational change of adenosine deaminase during ligand-exchange in a crystal.
Topics: Adenine; Adenosine Deaminase; Animals; Binding Sites; Cattle; Crystallography, X-Ray; Enzyme Inhibitors; Ligands; Protein Conformation; Tubercidin; Water | 2008 |