Page last updated: 2024-09-03

1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene and corticosterone

1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene has been researched along with corticosterone in 4 studies

Compound Research Comparison

Studies
(1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene)
Trials
(1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene)
Recent Studies (post-2010)
(1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene)
Studies
(corticosterone)
Trials
(corticosterone)
Recent Studies (post-2010) (corticosterone)
180127,1211246,622

Protein Interaction Comparison

ProteinTaxonomy1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene (IC50)corticosterone (IC50)
Solute carrier family 22 member 3Homo sapiens (human)0.945
Solute carrier family 22 member 3Rattus norvegicus (Norway rat)4.9
Solute carrier family 22 member 2Rattus norvegicus (Norway rat)4.1

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jönsson, CJ1
Bergman, A; Johansson, M; Larsson, C; Lund, BO1
Bergman , A; Brandt, I; Lindhe , O; Lund, BO1
Asp, V; Bergström, U; Brandt, I; Lindström, V; Olsson, JA1

Other Studies

4 other study(ies) available for 1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene and corticosterone

ArticleYear
Decreased plasma corticosterone levels in suckling mice following injection of the adrenal toxicant, MeSO2-DDE, to the lactating dam.
    Pharmacology & toxicology, 1994, Volume: 74, Issue:1

    Topics: Adrenal Cortex; Animals; Animals, Suckling; Corticosterone; Dichlorodiphenyl Dichloroethylene; Female; Lactation; Mice

1994
Structure-activity relationship for inhibition of CYP11B1-dependent glucocorticoid synthesis in Y1 cells by aryl methyl sulfones.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:5

    Topics: Adrenal Cortex; Animals; Cells, Cultured; Corticosterone; Dichlorodiphenyl Dichloroethylene; Environmental Pollutants; Enzyme Inhibitors; Mice; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship

1998
Irreversible binding and adrenocorticolytic activity of the DDT metabolite 3-methylsulfonyl-DDE examined in tissue-slice culture.
    Environmental health perspectives, 2001, Volume: 109, Issue:2

    Topics: Adrenal Cortex; Animals; Autoradiography; Biotransformation; Corticosterone; Culture Techniques; Dichlorodiphenyl Dichloroethylene; Female; Mice; Mice, Inbred C57BL; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Steroid 11-beta-Hydroxylase

2001
Cytotoxicity and decreased corticosterone production in adrenocortical Y-1 cells by 3-methylsulfonyl-DDE and structurally related molecules.
    Archives of toxicology, 2009, Volume: 83, Issue:4

    Topics: Adrenal Cortex; Animals; Cell Line; Cell Survival; Corticosterone; Dichlorodiphenyl Dichloroethylene; Drug Antagonism; Environmental Pollutants; Enzyme Inhibitors; Etomidate; Formazans; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Mice; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship; Tetrazolium Salts

2009