1-carboxyglutamic acid has been researched along with warfarin in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (51.61) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 2 (6.45) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Levy, RJ; Lian, JB | 1 |
| Knauer, GR; Matschiner, JT; Siegfried, CM | 1 |
| Friedman, PA; Lian, JB | 1 |
| Gardner, EJ; Hall, AL; Houser, RM; Jones, JP; Scheinbuks, J; Searcey, MT; Subba Rao, GN | 1 |
| Hauschka, PV; Reid, ML | 1 |
| Nishimoto, SK; Price, PA | 1 |
| Gallaher, KJ; Rannels, SR; Wolpert, EB | 1 |
| Canfield, LM; Gunn, JM; Johnson, TM; Martin, GS | 1 |
| Delmas, PD; Fournier, B; Gineyts, E | 1 |
| Kemp, SR; Lee, MW; Lewis, JW; Magilligan, DJ; Riddle, JM; Stein, PD | 1 |
| Dandona, P; Gill, DS; Kernoff, PB; Menon, RK; Thomas, M | 1 |
| Bovill, EG; Mann, KG | 1 |
| Lian, JB; Mosher, DF; Pauli, RM; Suttie, JW | 1 |
| Bernhard, WF; Levy, RJ; Zenker, JA | 1 |
| Fernlund, P; Stenflo, J | 1 |
| Suttie, JW | 1 |
| Bell, RG | 1 |
| Anderson, SA; Bach, AU; Foley, AL; Suttie, JW; Williams, EC | 1 |
| Arita, H; Higashino, K; Kawamoto, K; Kishino, J; Nakano, T; Nomura, K | 1 |
| Iwashita, M; Kudo, Y; Muraki, T; Takeda, Y | 1 |
| Abrams, WR; Enomoto-Iwamoto, M; Iwamoto, M; Koyama, E; Pacifici, M; Shapiro, IM; Suh, JY; Yagami, K | 1 |
| Blostein, M; Hasanbasic, I; Rajotte, I | 1 |
| Becker, RC | 1 |
| Hackeng, TM; Proudfoot, D; Schurgers, LJ; Shanahan, CM; Skepper, JN; Spronk, HM; Vermeer, C; Weissberg, PL | 1 |
| Benzakour, O; Coronas, V; Gely, A; Lara, R | 1 |
| Boström, KI; Shahbazian, A; Yao, Y | 1 |
| Kaplinska, K; Mielicki, WP | 1 |
| Atkins, GJ; Bonewald, LF; Findlay, DM; Welldon, KJ; Wijenayaka, AR | 1 |
| Grosch, M; Neacsu, CD; Paulsson, M; Tagariello, A; Tejada, M; Wagener, R; Winterpacht, A | 1 |
| Ferland, G | 1 |
| Cirilli, I; Dludla, PV; Kaesler, N; Marcheggiani, F; Orlando, P; Silvestri, S; Tiano, L | 1 |
4 review(s) available for 1-carboxyglutamic acid and warfarin
| Article | Year |
|---|---|
Warfarin and the biochemistry of the vitamin K dependent proteins.
Topics: 1-Carboxyglutamic Acid; Animals; Blood Coagulation; Blood Coagulation Factors; Humans; Multigene Family; Proteins; Serine Endopeptidases; Vitamin K; Warfarin | 1987 |
Mechanism of action of vitamin K: synthesis of gamma-carboxyglutamic acid.
Topics: 1-Carboxyglutamic Acid; Adenosine Triphosphate; Animals; Biotin; Carbon Dioxide; Carbon-Carbon Ligases; Coumarins; Glutamates; Humans; Ligases; Mixed Function Oxygenases; Molecular Conformation; Oxygen; Prothrombin; Substrate Specificity; Vitamin K; Vitamin K Epoxide Reductases | 1980 |
[Gas-6 and protein S: vitamin K-dependent factors and ligands for the TAM tyrosine kinase receptors family].
Topics: 1-Carboxyglutamic Acid; Acylation; Animals; Anticoagulants; Blood Coagulation; Carbon-Carbon Ligases; Endoplasmic Reticulum; Humans; Intercellular Signaling Peptides and Proteins; Liver; Mammals; Mice; Models, Biological; Multigene Family; Phagocytosis; Protein Processing, Post-Translational; Protein S; Rats; Receptor Protein-Tyrosine Kinases; Signal Transduction; Vitamin K; Warfarin | 2007 |
The discovery of vitamin K and its clinical applications.
Topics: 1-Carboxyglutamic Acid; Anticoagulants; Blood Coagulation; Calcification, Physiologic; Endocrine System; Hemostasis; History, 20th Century; History, 21st Century; Humans; Osteocalcin; Prothrombin; Terminology as Topic; Tissue Distribution; Vitamin K; Warfarin | 2012 |
27 other study(ies) available for 1-carboxyglutamic acid and warfarin
| Article | Year |
|---|---|
gamma-Carboxyglutamate excretion and warfarin therapy.
Topics: 1-Carboxyglutamic Acid; Adolescent; Adult; Child; Chromatography, Ion Exchange; Glutamates; Humans; Male; Prothrombin Time; Radioisotope Dilution Technique; Time Factors; Warfarin | 1979 |
Evidence for increased formation of preprothrombin and the noninvolvement of vitamin K-dependent reactions in sex-linked hyperprothrombinemia in the rat.
Topics: 1-Carboxyglutamic Acid; Amino Acids; Animals; Blood Coagulation Disorders; Cycloheximide; Female; Half-Life; In Vitro Techniques; Male; Microsomes, Liver; Protein Biosynthesis; Prothrombin; Rats; Sex Factors; Vitamin K; Vitamin K Deficiency; Warfarin | 1979 |
The vitamin K-dependent synthesis of gamma-carboxyglutamic acid by bone microsomes.
Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Chick Embryo; Glutamates; Microsomes; Oligopeptides; Vitamin K; Warfarin | 1978 |
Nature of the vitamin K-dependent CO2 fixation in microsomal membranes.
Topics: 1-Carboxyglutamic Acid; Animals; Carbon Dioxide; Carboxy-Lyases; Carrier Proteins; Glutamates; Intracellular Membranes; Microsomes, Liver; Peptides; Rats; Ribosomal Proteins; Structure-Activity Relationship; Vitamin K; Vitamin K Deficiency; Warfarin | 1978 |
Vitamin K dependence of a calcium-binding protein containing gamma-carboxyglutamic acid in chicken bone.
Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Calcium; Carrier Proteins; Chick Embryo; Chickens; Glutamates; Kinetics; Organ Specificity; Vitamin K; Warfarin | 1978 |
Proof that the gamma-carboxyglutamic acid-containing bone protein is synthesized in calf bone. Comparative synthesis rate and effect of coumadin on synthesis.
Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Cattle; Collagen; Glutamates; Kinetics; Proline; Protein Biosynthesis; Warfarin | 1979 |
Gamma-carboxyglutamic acid excretion into rat amniotic fluid during late gestation.
Topics: 1-Carboxyglutamic Acid; Amniotic Fluid; Animals; Creatinine; Female; Gestational Age; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Warfarin | 1990 |
Absorption and metabolism of vitamin K in Swiss 3T3 mouse fibroblasts--a model system for study of vitamin K absorption and metabolism.
Topics: 1-Carboxyglutamic Acid; Absorption; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Dicumarol; Fibroblasts; Mass Spectrometry; Mice; Models, Biological; Vitamin K; Vitamin K 1; Warfarin | 1987 |
Evidence that free gamma carboxyglutamic acid circulates in serum.
Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Hyperparathyroidism; Male; Methods; Peptides; Protein Binding; Rabbits; Vitamin K; Warfarin | 1989 |
Effect of warfarin on calcification of spontaneously degenerated porcine bioprosthetic valves.
Topics: 1-Carboxyglutamic Acid; Adult; Aged; Aortic Valve; Bioprosthesis; Calcinosis; Carbon-Carbon Ligases; Female; Glutamates; Glutamic Acid; Heart Valve Prosthesis; Humans; Ligases; Male; Middle Aged; Mitral Valve; Warfarin | 1985 |
Impaired carboxylation of osteocalcin in warfarin-treated patients.
Topics: 1-Carboxyglutamic Acid; Adult; Aged; Calcium-Binding Proteins; Female; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Osteocalcin; Vitamin K; Warfarin | 1987 |
Association of congenital deficiency of multiple vitamin K-dependent coagulation factors and the phenotype of the warfarin embryopathy: clues to the mechanism of teratogenicity of coumarin derivatives.
Topics: 1-Carboxyglutamic Acid; Abnormalities, Drug-Induced; Calcium-Binding Proteins; Child; Chromatography, High Pressure Liquid; Female; Fetal Diseases; Fingers; Humans; Male; Nose; Osteocalcin; Phenotype; Pregnancy; Prothrombin; Radiography; Vitamin K; Vitamin K 1; Vitamin K Deficiency; Warfarin | 1987 |
Porcine bioprosthetic valve calcification in bovine left ventricle-aorta shunts: studies of the deposition of vitamin K-dependent proteins.
Topics: 1-Carboxyglutamic Acid; Adolescent; Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Calcium-Binding Proteins; Cattle; Child; Child, Preschool; Heart Valve Prosthesis; Humans; Male; Osteocalcin; Prothrombin Time; Warfarin | 1983 |
Beta-hydroxyaspartic acid in vitamin K-dependent plasma proteins from scorbutic and warfarin-treated guinea pigs.
Topics: 1-Carboxyglutamic Acid; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Aspartic Acid; Blood Coagulation; Blood Proteins; Guinea Pigs; Hydroxylation; Protein Processing, Post-Translational; Vitamin K; Warfarin | 1984 |
Vitamin K-dependent carboxylation of glutamic acid residues to gamma-carboxyglutamic acid in lung microsomes.
Topics: 1-Carboxyglutamic Acid; Animals; Glutamates; Kinetics; Male; Microsomes; Peptides; Proteins; Rats; Structure-Activity Relationship; Vitamin K; Warfarin | 1980 |
Assessment of vitamin K status in human subjects administered "minidose" warfarin.
Topics: 1-Carboxyglutamic Acid; Adult; Aged; Anticoagulants; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Incidence; Male; Middle Aged; Osteocalcin; Prothrombin; Thrombosis; Vitamin K; Vitamin K 1; Warfarin | 1996 |
Requirement of gamma-carboxyglutamic acid residues for the biological activity of Gas6: contribution of endogenous Gas6 to the proliferation of vascular smooth muscle cells.
Topics: 1-Carboxyglutamic Acid; Animals; Anticoagulants; Blotting, Western; Calcium; Cell Division; Cells, Cultured; CHO Cells; Cricetinae; Epidermal Growth Factor; Intercellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Proteins; Rats; Structure-Activity Relationship; Thrombin; Vitamin K; Warfarin | 1997 |
Evidence for modulation of osteocalcin containing gamma-carboxyglutamic acid residues synthesis by insulin-like growth factor-I and vitamin K2 in human osteosarcoma cell line MG-63.
Topics: 1-Carboxyglutamic Acid; Cycloheximide; Humans; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor I; Osteoblasts; Osteocalcin; Osteosarcoma; Protein Synthesis Inhibitors; RNA, Messenger; Stimulation, Chemical; Tumor Cells, Cultured; Vitamin K; Warfarin | 1998 |
Matrix GLA protein is a developmental regulator of chondrocyte mineralization and, when constitutively expressed, blocks endochondral and intramembranous ossification in the limb.
Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Calcification, Physiologic; Calcium-Binding Proteins; Cells, Cultured; Chick Embryo; Chondrocytes; Extracellular Matrix Proteins; Gene Expression Regulation, Developmental; Limb Buds; Matrix Gla Protein; Microscopy, Electron, Scanning; Minerals; Osteogenesis; Vitamin K; Warfarin | 1999 |
The role of gamma-carboxylation in the anti-apoptotic function of gas6.
Topics: 1-Carboxyglutamic Acid; Animals; Apoptosis; Axl Receptor Tyrosine Kinase; Cells, Cultured; Endothelium, Vascular; Humans; Intercellular Signaling Peptides and Proteins; Mice; NIH 3T3 Cells; Oncogene Proteins; Phospholipids; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Umbilical Veins; Warfarin | 2005 |
Warfarin-induced vasculopathy.
Topics: 1-Carboxyglutamic Acid; Anticoagulants; Atherosclerosis; Calcinosis; Humans; Immunohistochemistry; Vascular Diseases; Warfarin | 2007 |
Post-translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification.
Topics: 1-Carboxyglutamic Acid; Adolescent; Adult; Amino Acid Sequence; Calcinosis; Calcium; Calcium-Binding Proteins; Cell Membrane; Cells, Cultured; Extracellular Matrix Proteins; Female; Humans; Male; Matrix Gla Protein; Middle Aged; Molecular Sequence Data; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Serine; Transport Vesicles; Vitamin K; Vitamin K 1; Warfarin | 2007 |
Proline and gamma-carboxylated glutamate residues in matrix Gla protein are critical for binding of bone morphogenetic protein-4.
Topics: 1-Carboxyglutamic Acid; Animals; Binding Sites; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Calcinosis; Calcium; Calcium-Binding Proteins; Cattle; Cell Line; Cells, Cultured; Chelating Agents; Edetic Acid; Endothelial Cells; Extracellular Matrix Proteins; Genes, Reporter; Humans; Matrix Gla Protein; Mice; Mutagenesis, Site-Directed; Osteogenesis; Pluripotent Stem Cells; Proline; Protein Binding; Recombinant Proteins; Transfection; Warfarin; Zebrafish Proteins | 2008 |
Direct analysis reveals an absence of gamma-carboxyglutamic acid in cancer procoagulant from human tissues.
Topics: 1-Carboxyglutamic Acid; Amnion; Antibodies, Monoclonal; Anticoagulants; Cell Line, Tumor; Chorion; Cysteine Endopeptidases; Enzyme Activation; Factor X; Female; Humans; Melanoma; Neoplasm Proteins; Pregnancy; Warfarin | 2009 |
Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by {gamma}-carboxylation-dependent and -independent mechanisms.
Topics: 1-Carboxyglutamic Acid; Calcification, Physiologic; Cell Differentiation; Cell Proliferation; Cells, Cultured; Humans; Metabolism; Osteoblasts; Osteocytes; Phenotype; Vitamin K; Vitamin K 1; Vitamin K 2; Vitamin K 3; Warfarin | 2009 |
Ucmaa (Grp-2) is required for zebrafish skeletal development. Evidence for a functional role of its glutamate γ-carboxylation.
Topics: 1-Carboxyglutamic Acid; Alternative Splicing; Amino Acid Sequence; Animals; Cartilage; Cloning, Molecular; Collagen Type II; Computational Biology; Embryo, Nonmammalian; Embryonic Development; Extracellular Matrix Proteins; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Intracellular Signaling Peptides and Proteins; Larva; Mice; Molecular Sequence Data; Notochord; Phenotype; Protein Isoforms; Proteins; Sequence Alignment; Sequence Homology; Staining and Labeling; Time Factors; Warfarin; Zebrafish; Zebrafish Proteins | 2011 |
Carboxylative efficacy of trans and cis MK7 and comparison with other vitamin K isomers.
Topics: 1-Carboxyglutamic Acid; Humans; Vitamin K; Vitamin K 1; Vitamin K 2; Warfarin | 2022 |