Page last updated: 2024-08-23

1-carboxyglutamic acid and vitamin k semiquinone radical

1-carboxyglutamic acid has been researched along with vitamin k semiquinone radical in 131 studies

Research

Studies (131)

Timeframe	Studies, this research(%)	All Research%
pre-1990	71 (54.20)	18.7374
1990's	29 (22.14)	18.2507
2000's	23 (17.56)	29.6817
2010's	7 (5.34)	24.3611
2020's	1 (0.76)	2.80

Authors

Authors	Studies
Gallop, P; Levy, RJ; Lian, JB	1
Adams, AB	1
Bell, RG	2
Fujikawa, K; Katayama, K; Titani, K	1
Davie, EW; DiScipio, RG	1
Knauer, GR; Matschiner, JT; Siegfried, CM	1
Esnouf, MP	1
Friedman, PA; Lian, JB	1
Canfield, LM; Carlisle, TL; Larson, AE; Suttie, JW	1
Gardner, EJ; Hall, AL; Houser, RM; Jones, JP; Scheinbuks, J; Searcey, MT; Subba Rao, GN	1
Gallop, PM; Hauschka, PV; Lian, JB	2
Hauschka, PV; Reid, ML	1
Olson, RE	1
Magnusson, S; Morris, HR; Petersen, TE; Sottrup-Jensen, L; Thøgersen, HC	1
Maddox, J	1
Cairns, JR; Price, PA; Williamson, MK	1
Berg, DT; Grinnell, BW; McClure, DB; Walls, JD; Yan, SB	1
Vermeer, C	4
Fujita, K; Kakehashi, H; Sakata, H; Yoshioka, H	1
Canfield, LM; Gunn, JM; Johnson, TM; Martin, GS	1
Boulanger, LL; Church, WR; Mann, KG; Messier, TL	1
Delmas, PD; Fournier, B; Gineyts, E	1
Baroncelli, GI; Bertelloni, S; Buggiani, B; Cosenza, GM; Ghirri, P; Saggese, G	1
Ryńca, J	1
Dandona, P; Gill, DS; Kernoff, PB; Menon, RK; Thomas, M	1
Friedman, PA; Przysiecki, CT	1
Guelpa, G; Leclerq, M; Pfister, CE; Robert, D; Werlen, D	1
Bergemer, AM; Besnard, JC; Fouquet, B; Goupille, P; Valat, C; Valat, JP	1
Devlin, VJ; Einhorn, TA; Gundberg, CM; Warman, J	1
Bigazzi, S; Francini, G; Gennari, C; Leone, V	1
Gundberg, CM; Lian, JB	1
Bovill, EG; Mann, KG	1
Soute, BA; van de Loo, PG; van Haarlem, LJ; Vermeer, C	1
Lian, JB; Mosher, DF; Pauli, RM; Suttie, JW	1
Chen, SH; Kurachi, K	1
Barza, M; Brown, AE; Furie, B; Furie, BC	1
Brown, CL; Cantor, AB; Furie, B; Furie, BC; Jorgensen, MJ; Shoemaker, CB	1
Angle, C; Lubinsky, M; Marsh, PW; Witkop, CJ	1
Price, PA; Williamson, MK	1
Canfield, LM	1
Borowski, M; Furie, B; Furie, BC	1
Bory, S; Dubois, J; Gaudry, M; Marquet, A	1
Esmon, CT	1
Bell, RG; Buchthal, SD	1
Brace, L	1
Fiore, CE; Malatino, LS; Tamburino, G	1
Borowski, M; Burnier, JP; Furie, B; Furie, BC	1
Gundberg, C; Levy, RJ; Scheinman, R	1
Kanai, Y; Sanada, K; Shimomura, H	1
Nelson, C; Price, PA; Williamson, MK	1
Friedman, PA	1
Fernlund, P; Stenflo, J	1
Fujikawa, K; Titani, K	1
Gallop, PM; Hauschka, PV; Traverso, HP	1
Suttie, JW	2
Furie, B; Nemerson, Y	1
Suttie, JW; Uotila, L	1
Bell, RG; Buchthal, SD; Laux, DC; McAllister, CG	1
Engelke, J; Goodman, HL; Kawai, M; Rich, DH; Suttie, JW	1
Nishimoto, SK; Price, PA	1
Baukol, SA; Price, PA	2
Kopeć, M	1
Bertrand, O; Dode, C; Elion, J; Labie, D; Rabiet, MJ	1
Kolb, E	1
Levy, RJ; Lian, JB; Zenker, JA	1
Bots, ML; Grobbee, DE; Jie, KS; Vermeer, C; Witteman, JC	1
Dowd, P; Ham, SW; Hershline, R; Naganathan, S	1
Howe, AM; Webster, WS	1
Bonvoisin, S; Copperé, B; Dechavanne, M; Delmas, PD; Gineyts, E; Hanss, M; Ninet, J	1
Ferland, G; O'Brien, ME; Sadowski, JA	1
Booth, SL; Dawson-Hughes, B; O'Brien, ME; Sadowski, JA; Sokoll, LJ; Tucker, K	1
Darden, T; Foley, C; Hiskey, R; Li, L; Pedersen, L	1
Sadowski, JA; Sokoll, LJ	1
Egan, JO; Kalafatis, M; Mann, KG; van't Veer, C	1
Anderson, SA; Bach, AU; Foley, AL; Suttie, JW; Williams, EC	1
Craciun, AM; Groenen-van Dooren, MM; Vermeer, C	1
Booth, SL; Davidson, KW; O'Brien, ME; Sadowski, JA; Sokoll, LJ; Tsaioun, KI	1
Bandyopadhyay, PK; Olivera, BM; Stafford, DW; Stanley, TB	1
Arita, H; Higashino, K; Kawamoto, K; Kishino, J; Nakano, T; Nomura, K	1
Furie, B; Furie, BC; Li, S; Walsh, CT	1
Davie, EW; Haldeman, BA; Harris, JE; Kulman, JD	1
Iwashita, M; Kudo, Y; Muraki, T; Takeda, Y	1
Booth, SL; Camilo, ME; Davidson, KW; O'Brien, ME; Paiva, SA; Russell, RM; Sadowski, JA; Sepe, TE	1
Houben, RJ; Mutucumarana, VP; Stafford, DW; Stanley, TB; Wu, SM	1
Davidson, KW; Huber, AM; O'Brien-Morse, ME; Sadowski, JA	1
Bouchard, BA; Furie, B; Furie, BC	1
Nelsestuen, GL; Ostrowski, BG	1
Abrams, WR; Enomoto-Iwamoto, M; Iwamoto, M; Koyama, E; Pacifici, M; Shapiro, IM; Suh, JY; Yagami, K	1
Brown, MA; Persson, U; Stenberg, LM; Stenflo, J	1
Sardana, MK; Uras, AR; Uras, F; Yardimci, T	1
Brown, MA; Ljungberg, O; Nilsson, E; Stenberg, LM; Stenflo, J	1
Ulrich, MM; Vermeer, C	1
Craciun, AM; Knapen, MH; Vermeer, C; Wolf, J	1
Brown, MA; Furie, B; Furie, BC; Hambe, B; Stenberg, LM; Stenflo, J	1
Chiba, M; Mitani, H; Yamaguchi, N	1
Blom, AM; Dahlbäck, B; Webb, JH	1
Abrams, TA; Burgess, BL; Hall, MO; Obin, MS; Prieto, AL	1
Begley, GS; Bronstein, M; Czerwiec, E; Furie, B; Furie, BC; Stenflo, J; Taylor, K	1
Gilbert, KA; Rannels, SR	1
Jin, DY; Lin, PJ; Makabe, KW; Stafford, DW; Wang, CP; Yagi, K	1
Furie, B; Furie, BC; Grant, MA; Huang, G; Huang, M; Morelli, X; Rigby, AC; Seaton, B	1
Lin, PJ; Stafford, DW; Straight, DL	1
Hamulyák, K; Vermeer, C	1
Kaneki, M	1
Stenflo, J	1
Davie, EW; Harris, JE; Kulman, JD; Nakazawa, N; Ogasawara, M; Satake, M	1
Davis, CH; Ii, DD; Pedersen, LG; Stafford, DW	1
Boscaro, M; Fiscaletti, P; Francucci, CM; Rilli, S	1
Hackeng, TM; Proudfoot, D; Schurgers, LJ; Shanahan, CM; Skepper, JN; Spronk, HM; Vermeer, C; Weissberg, PL	1
Benzakour, O; Coronas, V; Gely, A; Lara, R	1
Booth, SL; Erkkilä, AT	1
Atkins, GJ; Bonewald, LF; Findlay, DM; Welldon, KJ; Wijenayaka, AR	1
Rubinacci, A	1
Giriwono, PE; Goto, T; Iribe, M; Komai, M; Miura, A; Ohashi, A; Ohsaki, Y; Sato, S; Shirakawa, H	1
Theuwissen, E; Vermeer, C	1
Bretaña, NA; Chen, SA; Cheng, TH; Huang, KY; Lee, TY; Lu, CT; Su, MG	1
Ferland, G	1
Contaldi, P; Coppola, A; Franchini, M; Minno, GD; Tufano, A	1
Bajaj, SP; Fatemi, M; Messer, AS; Phillips, M; Vadivel, K; Vanderslice, NC; Velander, WH; Xu, W	1
Morrissey, JH	1
Cirilli, I; Dludla, PV; Kaesler, N; Marcheggiani, F; Orlando, P; Silvestri, S; Tiano, L	1

Reviews

29 review(s) available for 1-carboxyglutamic acid and vitamin k semiquinone radical

Article	Year
Metabolism of vitamin K and prothrombin synthesis: anticoagulants and the vitamin K--epoxide cycle. Federation proceedings, 1978, Volume: 37, Issue:12 Topics: 1-Carboxyglutamic Acid; Animals; Anticoagulants; Cricetinae; Drug Resistance; Endoplasmic Reticulum; Epoxy Compounds; Humans; Liver; Mitochondria, Liver; Oxidoreductases; Prothrombin; Rats; Vitamin K; Vitamin K 1	1978
[Vitamin K-dependent blood coagulation factors--structure, function and biosynthesis (author's transl)]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1979, Volume: 24, Issue:7 Topics: 1-Carboxyglutamic Acid; Animals; Blood Coagulation Factors; Cattle; Factor IX; Factor VII; Factor X; Prothrombin; Structure-Activity Relationship; Vitamin K	1979
Gamma-carboxyglutamate-containing proteins and the vitamin K-dependent carboxylase. The Biochemical journal, 1990, Mar-15, Volume: 266, Issue:3 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Carbon-Carbon Ligases; Humans; Ligases; Molecular Sequence Data; Nutritional Requirements; Vitamin K	1990
[Role of vitamin K in protein modification]. Postepy biochemii, 1985, Volume: 31, Issue:2 Topics: 1-Carboxyglutamic Acid; Blood Coagulation; Blood Coagulation Factors; Calcium-Binding Proteins; Chemical Phenomena; Chemistry; Glutamates; Glutamic Acid; Glycoproteins; Humans; Microsomes, Liver; Models, Biological; Osteocalcin; Protein Binding; Protein C; Protein S; Vitamin K	1985
Vitamin K-dependent carboxylation. The International journal of biochemistry, 1987, Volume: 19, Issue:1 Topics: 1-Carboxyglutamic Acid; Animals; Biomarkers; Carbon Dioxide; Carbon-Carbon Ligases; Humans; Ligases; Microsomes, Liver; Protein Precursors; Protein Processing, Post-Translational; Prothrombin; Substrate Specificity; Vitamin K	1987
Osteocalcin. Biochemical considerations and clinical applications. Clinical orthopaedics and related research, 1988, Issue:226 Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Bone Diseases, Metabolic; Calcium-Binding Proteins; Chemical Phenomena; Chemistry; Hormones; Humans; Osteocalcin; Osteogenesis; Radioimmunoassay; Rats; Structure-Activity Relationship; Vitamin K	1988
Warfarin and the biochemistry of the vitamin K dependent proteins. Advances in experimental medicine and biology, 1987, Volume: 214 Topics: 1-Carboxyglutamic Acid; Animals; Blood Coagulation; Blood Coagulation Factors; Humans; Multigene Family; Proteins; Serine Endopeptidases; Vitamin K; Warfarin	1987
Protein C. Progress in hemostasis and thrombosis, 1984, Volume: 7 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Anticoagulants; Antithrombin III; Blood Coagulation; Blood Coagulation Factors; Blood Proteins; Blood Vessels; Calcium; Carrier Proteins; Cattle; Dogs; Endothelium; Factor V; Factor Va; Factor VIII; Factor VIIIa; Factor X; Factor Xa; Fibrinolysis; Glycoproteins; Humans; Integrin alphaXbeta2; Models, Biological; Plasminogen Activators; Platelet Membrane Glycoproteins; Protein C; Protein C Inhibitor; Protein Precursors; Protein S; Receptors, Cell Surface; Receptors, Thrombin; Substrate Specificity; Thrombin; Vitamin K	1984
The pharmacology and therapeutics of vitamin K. The American journal of medical technology, 1983, Volume: 49, Issue:6 Topics: 1-Carboxyglutamic Acid; Animals; Anticoagulants; Calcium-Binding Proteins; History, 19th Century; History, 20th Century; Humans; Infant, Newborn; Liver; Protein Precursors; Prothrombin; Rodenticides; United States; Vitamin K; Vitamin K Deficiency; Vitamin K Deficiency Bleeding	1983
The vitamin K-dependent carboxylation reaction. Molecular and cellular biochemistry, 1984, Volume: 61, Issue:1 Topics: 1-Carboxyglutamic Acid; Animals; Calcium-Binding Proteins; Carbon-Carbon Ligases; Cattle; Humans; In Vitro Techniques; Ligases; Microsomes, Liver; Mixed Function Oxygenases; Models, Chemical; Organ Specificity; Osteocalcin; Protein Processing, Post-Translational; Rats; Substrate Specificity; Vitamin K; Vitamin K Epoxide Reductases	1984
[Bone Gla-protein (osteocalcin): a new metabolic marker of calcified tissues]. Recenti progressi in medicina, 1984, Volume: 75, Issue:4 Topics: 1-Carboxyglutamic Acid; Adult; Bone and Bones; Bone Diseases; Bone Neoplasms; Calcium-Binding Proteins; Chronic Kidney Disease-Mineral and Bone Disorder; Female; Humans; Hyperparathyroidism; Male; Osteitis Deformans; Osteocalcin; Radioimmunoassay; Vitamin K	1984
Gamma-carboxyglutamic acid. Molecular and cellular biochemistry, 1981, Sep-25, Volume: 39 Topics: 1-Carboxyglutamic Acid; Animals; Arteriosclerosis; Binding Sites; Blood Proteins; Calcification, Physiologic; Calcinosis; Calcium; Calcium-Binding Proteins; Chemical Phenomena; Chemistry; Factor IX; Factor VII; Factor X; Glutamates; Glycoproteins; Humans; Metals; Osteocalcin; Protein C; Protein S; Proteins; Prothrombin; Urinary Calculi; Vitamin K	1981
The structural aspects of vitamin K-dependent blood coagulation factors. Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1982, Volume: 45, Issue:4 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Blood Coagulation Factors; Cattle; Chemistry; Factor IX; Factor VII; Factor X; Glycoproteins; History, 20th Century; Humans; Peptide Hydrolases; Protein Binding; Prothrombin; Vitamin K	1982
Mechanism of action of vitamin K: synthesis of gamma-carboxyglutamic acid. CRC critical reviews in biochemistry, 1980, Volume: 8, Issue:2 Topics: 1-Carboxyglutamic Acid; Adenosine Triphosphate; Animals; Biotin; Carbon Dioxide; Carbon-Carbon Ligases; Coumarins; Glutamates; Humans; Ligases; Mixed Function Oxygenases; Molecular Conformation; Oxygen; Prothrombin; Substrate Specificity; Vitamin K; Vitamin K Epoxide Reductases	1980
Zymogens and cofactors of blood coagulation. CRC critical reviews in biochemistry, 1980, Volume: 9, Issue:1 Topics: 1-Carboxyglutamic Acid; Animals; Blood Coagulation; Blood Coagulation Factors; Cattle; Cell Membrane; Enzyme Activation; Enzyme Precursors; Factor IX; Factor VII; Factor VIII; Factor X; Factor XI; Factor XII; Humans; Kininogens; Metals; Prekallikrein; Protein Conformation; Prothrombin; Rabbits; Vitamin K	1980
Carboxylated calcium-binding proteins and vitamin K. The New England journal of medicine, 1980, Jun-26, Volume: 302, Issue:26 Topics: 1-Carboxyglutamic Acid; Adolescent; Adult; Animals; Blood Coagulation; Blood Coagulation Factors; Blood Coagulation Tests; Blood Proteins; Bone Diseases, Metabolic; Bone Matrix; Calcium; Calcium-Binding Proteins; Carboxylic Acids; Child, Preschool; Female; Glutamates; Humans; Infant, Newborn; Osteocalcin; Rats; Vitamin K; Vitamin K Deficiency Bleeding	1980
[Vitamin K dependent blood clotting proteins (author's transl)]. Postepy biochemii, 1980, Volume: 26, Issue:1 Topics: 1-Carboxyglutamic Acid; Animals; Blood Coagulation; Calcium; Carboxylic Acids; Cattle; Factor IX; Factor VII; Factor X; Glycoproteins; Humans; Liver; Microsomes; Models, Biological; Phospholipids; Prothrombin; Rats; Thrombin; Vitamin K; Vitamin K Deficiency	1980
Vitamin K and energy transduction: a base strength amplification mechanism. Science (New York, N.Y.), 1995, Sep-22, Volume: 269, Issue:5231 Topics: 1-Carboxyglutamic Acid; Animals; Binding Sites; Blood Coagulation Factors; Calcium; Carbon-Carbon Ligases; Cyanides; Energy Metabolism; Hydrogen-Ion Concentration; Ligases; Molecular Conformation; Oxidation-Reduction; Oxygen; Thermodynamics; Vitamin K; Vitamin K 1	1995
Vitamin K--its essential role in craniofacial development. A review of the literature regarding vitamin K and craniofacial development. Australian dental journal, 1994, Volume: 39, Issue:2 Topics: 1-Carboxyglutamic Acid; Animals; Calcium-Binding Proteins; Extracellular Matrix Proteins; Facial Bones; Female; Humans; Matrix Gla Protein; Osteocalcin; Pregnancy; Rats; Skull; Vitamin K; Vitamin K Deficiency	1994
Regulation and regulatory role of gamma-carboxyglutamic acid containing clotting factors. Critical reviews in eukaryotic gene expression, 1996, Volume: 6, Issue:1 Topics: 1-Carboxyglutamic Acid; Animals; Blood Coagulation; Cell Membrane; Coagulants; Enzyme Precursors; Enzymes; Humans; Vitamin K	1996
Vitamin K-dependent biosynthesis of gamma-carboxyglutamic acid. Blood, 1999, Mar-15, Volume: 93, Issue:6 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Blood Coagulation Factors; Carbon-Carbon Ligases; Humans; Molecular Sequence Data; Vitamin K	1999
Membrane association with multiple calcium ions: vitamin-K-dependent proteins, annexins and pentraxins. Current opinion in structural biology, 1999, Volume: 9, Issue:4 Topics: 1-Carboxyglutamic Acid; Alpha-Globulins; Amino Acid Substitution; Annexins; Binding Sites; C-Reactive Protein; Calcium; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Consensus Sequence; Humans; Lysine; Membrane Lipids; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Sequence Alignment; Sequence Homology, Amino Acid; Serum Amyloid P-Component; Static Electricity; Vitamin K	1999
[Protective effects of vitamin K against osteoporosis and its pleiotropic actions]. Clinical calcium, 2006, Volume: 16, Issue:9 Topics: 1-Carboxyglutamic Acid; Antioxidants; Carcinoma, Hepatocellular; Fractures, Bone; Humans; Liver Neoplasms; Osteoporosis; Pregnane X Receptor; Receptors, Steroid; Soy Foods; Transcription, Genetic; Vitamin K; Vitamin K 1; Vitamin K 2	2006
Role of vitamin K on biochemical markers, bone mineral density, and fracture risk. Journal of endocrinological investigation, 2007, Volume: 30, Issue:6 Suppl Topics: 1-Carboxyglutamic Acid; Biomarkers; Bone Density; Fractures, Bone; Humans; Nutritional Status; Osteoporosis; Risk Factors; Vitamin K; Vitamins	2007
[Gas-6 and protein S: vitamin K-dependent factors and ligands for the TAM tyrosine kinase receptors family]. Medecine sciences : M/S, 2007, Volume: 23, Issue:10 Topics: 1-Carboxyglutamic Acid; Acylation; Animals; Anticoagulants; Blood Coagulation; Carbon-Carbon Ligases; Endoplasmic Reticulum; Humans; Intercellular Signaling Peptides and Proteins; Liver; Mammals; Mice; Models, Biological; Multigene Family; Phagocytosis; Protein Processing, Post-Translational; Protein S; Rats; Receptor Protein-Tyrosine Kinases; Signal Transduction; Vitamin K; Warfarin	2007
Vitamin K intake and atherosclerosis. Current opinion in lipidology, 2008, Volume: 19, Issue:1 Topics: 1-Carboxyglutamic Acid; Atherosclerosis; Calcinosis; Diet; Humans; Mutation; Vitamin K	2008
Vitamin K, osteoporosis and degenerative diseases of ageing. Menopause international, 2011, Volume: 17, Issue:1 Topics: 1-Carboxyglutamic Acid; Bone and Bones; Humans; Neurodegenerative Diseases; Osteoporosis; Vitamin K; Vitamin K Deficiency; Vitamins	2011
The discovery of vitamin K and its clinical applications. Annals of nutrition & metabolism, 2012, Volume: 61, Issue:3 Topics: 1-Carboxyglutamic Acid; Anticoagulants; Blood Coagulation; Calcification, Physiologic; Endocrine System; Hemostasis; History, 20th Century; History, 21st Century; Humans; Osteocalcin; Prothrombin; Terminology as Topic; Tissue Distribution; Vitamin K; Warfarin	2012
Oral anticoagulant drugs and the risk of osteoporosis: new anticoagulants better than old? Seminars in thrombosis and hemostasis, 2015, Volume: 41, Issue:4 Topics: 1-Carboxyglutamic Acid; Administration, Oral; Animals; Anticoagulants; Humans; Osteoporosis; Protein Processing, Post-Translational; Vitamin K	2015

Trials

3 trial(s) available for 1-carboxyglutamic acid and vitamin k semiquinone radical

Article	Year
Defects in vitamin K-dependent carboxylation associated with moxalactam treatment. The Journal of infectious diseases, 1986, Volume: 153, Issue:6 Topics: 1-Carboxyglutamic Acid; Adult; Humans; Moxalactam; Piperacillin; Prothrombin; Prothrombin Time; Ticarcillin; Vitamin K	1986
Changes in serum osteocalcin, plasma phylloquinone, and urinary gamma-carboxyglutamic acid in response to altered intakes of dietary phylloquinone in human subjects. The American journal of clinical nutrition, 1997, Volume: 65, Issue:3 Topics: 1-Carboxyglutamic Acid; Adult; Antifibrinolytic Agents; Diet; Female; Humans; Male; Nutritional Status; Osteocalcin; Prothrombin Time; Vitamin K; Vitamin K 1	1997
Interaction between vitamin K nutriture and bacterial overgrowth in hypochlorhydria induced by omeprazole. The American journal of clinical nutrition, 1998, Volume: 68, Issue:3 Topics: 1-Carboxyglutamic Acid; Achlorhydria; Adult; Aged; Bacteria; Biomarkers; Cross-Over Studies; Diet; Drug Interactions; Humans; Intestine, Small; Middle Aged; Omeprazole; Osteocalcin; Protein Precursors; Prothrombin; Vitamin K; Vitamin K 1; Vitamin K Deficiency	1998

Other Studies

99 other study(ies) available for 1-carboxyglutamic acid and vitamin k semiquinone radical

Article	Year
Atherocalcin, a gamma-carboxyglutamic acid containing protein from atherosclerotic plaque. Biochemical and biophysical research communications, 1979, Nov-14, Volume: 91, Issue:1 Topics: 1-Carboxyglutamic Acid; Adult; Aged; Amino Acids; Aorta; Arteriosclerosis; Blood Proteins; Calcium; Calcium-Binding Proteins; Edetic Acid; Female; Glutamates; Humans; Immunodiffusion; Male; Middle Aged; Molecular Weight; Vitamin K	1979
The role of vitamin K in biological calcification. The Journal of the Nebraska Dental Association, 1979,Autumn, Volume: 56, Issue:1 Topics: 1-Carboxyglutamic Acid; Animals; Calcification, Physiologic; Glutamates; Humans; Tooth Calcification; Vitamin K	1979
Characterization of protein S, a gamma-carboxyglutamic acid containing protein from bovine and human plasma. Biochemistry, 1979, Mar-06, Volume: 18, Issue:5 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Amino Acids; Animals; Blood Coagulation Factors; Carbohydrates; Cattle; Glycoproteins; Humans; Molecular Weight; Species Specificity; Vitamin K	1979
Osteocalcin: a vitamin K-dependent calcium-binding protein in bone. Nutrition reviews, 1979, Volume: 37, Issue:2 Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Bone Development; Calcium; Carrier Proteins; Chick Embryo; Glutamates; Protein Precursors; Vitamin K	1979
Evidence for increased formation of preprothrombin and the noninvolvement of vitamin K-dependent reactions in sex-linked hyperprothrombinemia in the rat. Archives of biochemistry and biophysics, 1979, Volume: 194, Issue:2 Topics: 1-Carboxyglutamic Acid; Amino Acids; Animals; Blood Coagulation Disorders; Cycloheximide; Female; Half-Life; In Vitro Techniques; Male; Microsomes, Liver; Protein Biosynthesis; Prothrombin; Rats; Sex Factors; Vitamin K; Vitamin K Deficiency; Warfarin	1979
The vitamin K-dependent proteins. Biochemical Society transactions, 1979, Volume: 7, Issue:4 Topics: 1-Carboxyglutamic Acid; Animals; Blood Coagulation Factors; Blood Proteins; Cattle; Factor IX; Factor VII; Factor X; Humans; Prothrombin; Vitamin K; Vitamin K Deficiency	1979
The vitamin K-dependent synthesis of gamma-carboxyglutamic acid by bone microsomes. The Journal of biological chemistry, 1978, Oct-10, Volume: 253, Issue:19 Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Chick Embryo; Glutamates; Microsomes; Oligopeptides; Vitamin K; Warfarin	1978
Relationship between vitamin K-dependent carboxylation and vitamin K epoxidation. Federation proceedings, 1978, Volume: 37, Issue:12 Topics: 1-Carboxyglutamic Acid; Animals; Carbon Dioxide; Carboxy-Lyases; Epoxy Compounds; Glutamates; Kinetics; Microsomes, Liver; Peroxidases; Prothrombin; Rats; Vitamin K	1978
Nature of the vitamin K-dependent CO2 fixation in microsomal membranes. Federation proceedings, 1978, Volume: 37, Issue:12 Topics: 1-Carboxyglutamic Acid; Animals; Carbon Dioxide; Carboxy-Lyases; Carrier Proteins; Glutamates; Intracellular Membranes; Microsomes, Liver; Peptides; Rats; Ribosomal Proteins; Structure-Activity Relationship; Vitamin K; Vitamin K Deficiency; Warfarin	1978
Properties and biosynthesis of a vitamin K-dependent calcium binding protein in bone. Federation proceedings, 1978, Volume: 37, Issue:12 Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Bone Development; Calcification, Physiologic; Calcinosis; Calcium; Carboxy-Lyases; Carrier Proteins; Chickens; Culture Techniques; Microsomes; Vitamin K	1978
Vitamin K dependence of a calcium-binding protein containing gamma-carboxyglutamic acid in chicken bone. The Journal of biological chemistry, 1978, 12-25, Volume: 253, Issue:24 Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Calcium; Carrier Proteins; Chick Embryo; Chickens; Glutamates; Kinetics; Organ Specificity; Vitamin K; Warfarin	1978
New developments in the study of the vitamin K-dependent carboxylation system. World review of nutrition and dietetics, 1978, Volume: 31 Topics: 1-Carboxyglutamic Acid; Animals; Carboxy-Lyases; In Vitro Techniques; Microsomes, Liver; Prothrombin; Rats; Vitamin K	1978
The N-terminal sequences of blood coagulation factor X1 and X2 light chains. Mass-spectrometric identification of twelve residues of gamma-carboxyglutamic acid in their vitamin K-dependent domains. The Biochemical journal, 1978, Nov-01, Volume: 175, Issue:2 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Cattle; Factor X; Glutamates; Mass Spectrometry; Peptide Fragments; Vitamin K	1978
The working of vitamin K. Nature, 1991, Oct-24, Volume: 353, Issue:6346 Topics: 1-Carboxyglutamic Acid; Animals; Glutamates; Glutamic Acid; Vitamin K	1991
Direct identification of gamma-carboxyglutamic acid in the sequencing of vitamin K-dependent proteins. Analytical biochemistry, 1991, Nov-15, Volume: 199, Issue:1 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Calcium-Binding Proteins; Cattle; Chromatography, High Pressure Liquid; Extracellular Matrix Proteins; Glutamates; Indicators and Reagents; Matrix Gla Protein; Osteocalcin; Phenylthiohydantoin; Prothrombin; Vitamin K	1991
Viral transformation increases vitamin K-dependent gamma-carboxylation of glutamate. Experimental cell research, 1991, Volume: 192, Issue:1 Topics: 1-Carboxyglutamic Acid; Adenovirus Early Proteins; Adenoviruses, Human; Animals; Calcium; Cell Line, Transformed; Cell Transformation, Viral; DNA, Viral; Humans; Microsomes; Oncogene Proteins, Viral; Protein C; Protein Processing, Post-Translational; Recombinant Proteins; Vitamin K	1991
Effects of aztreonam on fecal flora and on vitamin K metabolism. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:6 Topics: 1-Carboxyglutamic Acid; Aztreonam; Biomarkers; Child, Preschool; Colony Count, Microbial; Feces; Humans; Infant; Protein Precursors; Prothrombin; Vitamin K	1990
Absorption and metabolism of vitamin K in Swiss 3T3 mouse fibroblasts--a model system for study of vitamin K absorption and metabolism. Biochemical and biophysical research communications, 1987, Sep-15, Volume: 147, Issue:2 Topics: 1-Carboxyglutamic Acid; Absorption; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Dicumarol; Fibroblasts; Mass Spectrometry; Mice; Models, Biological; Vitamin K; Vitamin K 1; Warfarin	1987
Evidence for a common metal ion-dependent transition in the 4-carboxyglutamic acid domains of several vitamin K-dependent proteins. The Journal of biological chemistry, 1989, Oct-25, Volume: 264, Issue:30 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Calcium; Cations, Divalent; Cattle; Epitopes; Factor VII; Factor X; Humans; Molecular Sequence Data; Oligopeptides; Protein C; Prothrombin; Vitamin K	1989
Evidence that free gamma carboxyglutamic acid circulates in serum. Clinica chimica acta; international journal of clinical chemistry, 1989, Jun-30, Volume: 182, Issue:2 Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Hyperparathyroidism; Male; Methods; Peptides; Protein Binding; Rabbits; Vitamin K; Warfarin	1989
[Calciotropic hormones in osteoporosis caused by anorexia nervosa]. Minerva pediatrica, 1989, Volume: 41, Issue:2 Topics: 1-Carboxyglutamic Acid; Adolescent; Adult; Anorexia Nervosa; Bone and Bones; Calcitonin; Calcium; Calcium-Binding Proteins; Child; Female; Homeostasis; Humans; Hydroxycholecalciferols; Male; Minerals; Osteocalcin; Osteoporosis; Parathyroid Hormone; Vitamin K	1989
Impaired carboxylation of osteocalcin in warfarin-treated patients. The Journal of clinical endocrinology and metabolism, 1987, Volume: 64, Issue:1 Topics: 1-Carboxyglutamic Acid; Adult; Aged; Calcium-Binding Proteins; Female; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Osteocalcin; Vitamin K; Warfarin	1987
[Modifications in the urinary excretion of gamma-carboxyglutamic acid induced by vitamin K]. Schweizerische medizinische Wochenschrift, 1988, Feb-13, Volume: 118, Issue:6 Topics: 1-Carboxyglutamic Acid; Adult; Calcium; Calcium Carbonate; Calcium-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Osteocalcin; Vitamin K	1988
[Osteocalcin and anomalies of cellular immunity in rheumatoid polyarthritis]. Revue du rhumatisme et des maladies osteo-articulaires, 1988, Volume: 55, Issue:8 Topics: 1-Carboxyglutamic Acid; Arthritis, Rheumatoid; Bone and Bones; Calcium-Binding Proteins; Female; Humans; Immunoglobulin M; Leukocyte Count; Male; Middle Aged; Osteocalcin; Rheumatoid Factor; T-Lymphocytes; Vitamin K	1988
Fracture healing and osteocalcin metabolism in vitamin K deficiency. Clinical orthopaedics and related research, 1988, Issue:237 Topics: 1-Carboxyglutamic Acid; Animals; Bony Callus; Calcium-Binding Proteins; Femoral Fractures; Male; Osteocalcin; Prothrombin Time; Rats; Rats, Inbred Strains; Vitamin K; Vitamin K Deficiency; Wound Healing	1988
Serum osteocalcin concentration in patients with prostatic cancer. American journal of clinical oncology, 1988, Volume: 11 Suppl 2 Topics: 1-Carboxyglutamic Acid; Acid Phosphatase; Aged; Aged, 80 and over; Alkaline Phosphatase; Biomarkers, Tumor; Bone and Bones; Bone Neoplasms; Calcium-Binding Proteins; Humans; Hydroxyproline; Male; Middle Aged; Neoplasms, Hormone-Dependent; Osteocalcin; Prostatic Neoplasms; Radionuclide Imaging; Vitamin K	1988
The effect of Gla-containing proteins on the precipitation of insoluble salts. Biochemical and biophysical research communications, 1987, Jan-15, Volume: 142, Issue:1 Topics: 1-Carboxyglutamic Acid; Calcium Phosphates; Calcium-Binding Proteins; Cations, Divalent; Chemical Precipitation; Factor X; Osteocalcin; Phosphates; Salts; Solubility; Vitamin K	1987
Association of congenital deficiency of multiple vitamin K-dependent coagulation factors and the phenotype of the warfarin embryopathy: clues to the mechanism of teratogenicity of coumarin derivatives. American journal of human genetics, 1987, Volume: 41, Issue:4 Topics: 1-Carboxyglutamic Acid; Abnormalities, Drug-Induced; Calcium-Binding Proteins; Child; Chromatography, High Pressure Liquid; Female; Fetal Diseases; Fingers; Humans; Male; Nose; Osteocalcin; Phenotype; Pregnancy; Prothrombin; Radiography; Vitamin K; Vitamin K 1; Vitamin K Deficiency; Warfarin	1987
Human genes for factor IX and other vitamin K dependent blood proteins. Advances in experimental medicine and biology, 1987, Volume: 214 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Blood Coagulation Factors; Exons; Factor IX; Genes; Humans; Introns; Molecular Sequence Data; Mutation; Polymorphism, Genetic; Protein Conformation; Vitamin K	1987
Recognition site directing vitamin K-dependent gamma-carboxylation resides on the propeptide of factor IX. Cell, 1987, Jan-30, Volume: 48, Issue:2 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Cell Line; DNA; Factor IX; Mutation; Peptides; Protein Precursors; Protein Processing, Post-Translational; Transfection; Vitamin K	1987
Syndrome of amelogenesis imperfecta, nephrocalcinosis, impaired renal concentration, and possible abnormality of calcium metabolism. American journal of medical genetics, 1985, Volume: 20, Issue:2 Topics: 1-Carboxyglutamic Acid; Amelogenesis Imperfecta; Biopsy; Calcium Metabolism Disorders; Calcium-Binding Proteins; Child; Female; Genes, Recessive; Humans; Kidney; Kidney Concentrating Ability; Male; Nephrocalcinosis; Osteocalcin; Radiography; Syndrome; Tooth; Vitamin K	1985
[The biochemistry of vitamin K]. Nederlands tijdschrift voor geneeskunde, 1985, Apr-27, Volume: 129, Issue:17 Topics: 1-Carboxyglutamic Acid; Blood Coagulation Factors; Calcium; Calcium-Binding Proteins; Carboxy-Lyases; Carrier Proteins; Humans; Osteocalcin; Protein Binding; Protein Biosynthesis; Vitamin K	1985
Primary structure of bovine matrix Gla protein, a new vitamin K-dependent bone protein. The Journal of biological chemistry, 1985, Dec-05, Volume: 260, Issue:28 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Autoanalysis; Calcium-Binding Proteins; Carboxypeptidases; Cattle; Chromatography, High Pressure Liquid; Disulfides; Extracellular Matrix Proteins; Matrix Gla Protein; Osteocalcin; Skatole; Solubility; Trypsin; Vitamin K; Water	1985
Oxygen requirements for vitamin K-dependent carboxylation and epoxide formation. Biochimica et biophysica acta, 1986, Jan-17, Volume: 869, Issue:1 Topics: 1-Carboxyglutamic Acid; Epoxy Compounds; Glutamates; Oxygen; Protein Processing, Post-Translational; Vitamin K	1986
Distribution of gamma-carboxyglutamic acid residues in partially carboxylated human prothrombins. The Journal of biological chemistry, 1986, Feb-05, Volume: 261, Issue:4 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Binding Sites; Calcium; Glutamates; Humans; Protein Conformation; Prothrombin; Vitamin K	1986
Vitamin K dependent carboxylation: synthesis and biological properties of tetrazolyl analogues of pentapeptidic substrates. Journal of medicinal chemistry, 1984, Volume: 27, Issue:9 Topics: 1-Carboxyglutamic Acid; Electron Spin Resonance Spectroscopy; Glutamates; Oligopeptides; Structure-Activity Relationship; Substrate Specificity; Vitamin K	1984
Vitamin K dependent carboxylation of glutamate residues to gamma-carboxyglutamate in microsomes from spleen and testes: comparison with liver, lung, and kidney. Biochemistry, 1983, Mar-01, Volume: 22, Issue:5 Topics: 1-Carboxyglutamic Acid; Animals; Glutamates; Glutamic Acid; Kidney; Lung; Male; Microsomes; Microsomes, Liver; Rats; Rats, Inbred Strains; Spleen; Testis; Vitamin K	1983
The identification of the vitamin K-dependent bone protein osteocalcin as one of the gamma-carboxyglutamic acid containing proteins present in calcified atherosclerotic plaque and mineralized heart valves. Atherosclerosis, 1983, Volume: 46, Issue:1 Topics: 1-Carboxyglutamic Acid; Adult; Aged; Arteriosclerosis; Bone and Bones; Calcinosis; Calcium-Binding Proteins; Child; Child, Preschool; Glutamates; Heart Valves; Humans; Middle Aged; Osteocalcin; Proteins; Vitamin D; Vitamin K	1983
[Amino acid composition of osteocalcin in the maxillary bone of cats]. Shigaku = Odontology; journal of Nihon Dental College, 1983, Volume: 70, Issue:6 Topics: 1-Carboxyglutamic Acid; Amino Acids; Animals; Calcium-Binding Proteins; Cats; Maxilla; Osteocalcin; Vitamin K	1983
The binding of Gla-containing proteins to phospholipids. FEBS letters, 1984, Jul-23, Volume: 173, Issue:1 Topics: 1-Carboxyglutamic Acid; Blood Coagulation; Calcium; Calcium-Binding Proteins; Glutamates; Osteocalcin; Phospholipids; Prothrombin; Prothrombin Time; Structure-Activity Relationship; Vitamin K	1984
Chemical modification of gamma-carboxyglutamic acid, the vitamin K-dependent amino acid which binds Ca2+. Analytical biochemistry, 1984, Volume: 136, Issue:1 Topics: 1-Carboxyglutamic Acid; Calcium; Chemical Phenomena; Chemistry; Decarboxylation; Glutamates; Isotope Labeling; Proteins; Pyrrolidonecarboxylic Acid; Tritium; Vitamin K	1984
Vitamin K-dependent proteins. The New England journal of medicine, 1984, May-31, Volume: 310, Issue:22 Topics: 1-Carboxyglutamic Acid; Glutamates; Humans; Proteins; Prothrombin; Vitamin K	1984
Beta-hydroxyaspartic acid in vitamin K-dependent plasma proteins from scorbutic and warfarin-treated guinea pigs. FEBS letters, 1984, Mar-26, Volume: 168, Issue:2 Topics: 1-Carboxyglutamic Acid; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Aspartic Acid; Blood Coagulation; Blood Proteins; Guinea Pigs; Hydroxylation; Protein Processing, Post-Translational; Vitamin K; Warfarin	1984
Vitamin K-dependent gamma-carboxyglutamic acid formation by mouse renal adenocarcinoma cells (RAG). Calcified tissue international, 1980, Volume: 30, Issue:1 Topics: 1-Carboxyglutamic Acid; Adenocarcinoma; Animals; Calcium; Carbon-Carbon Ligases; Glutamates; Kidney; Kidney Neoplasms; Ligases; Mice; Neoplasms, Experimental; Protein Biosynthesis; Vitamin K	1980
Recent findings in understanding the biological function of vitamin K. Medical biology, 1982, Volume: 60, Issue:1 Topics: 1-Carboxyglutamic Acid; 4-Hydroxycoumarins; Animals; Blood Coagulation Factors; Carbon Dioxide; Carbon-Carbon Ligases; Cattle; Chemical Phenomena; Chemistry; Ligases; Microsomes, Liver; Mixed Function Oxygenases; Models, Biological; Prothrombin; Rats; Vitamin K; Vitamin K Epoxide Reductases	1982
Vitamin K dependent formation of gamma-carboxyglutamate residues in tumor microsomes. Biochemical and biophysical research communications, 1982, Nov-16, Volume: 109, Issue:1 Topics: 1-Carboxyglutamic Acid; Animals; Cell Line; Glutamates; Kinetics; Lymphoma; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Melanoma; Mice; Mice, Inbred BALB C; Microsomes; Neoplasm Proteins; Neoplasms, Experimental; Vitamin K	1982
Vitamin K-dependent carboxylase: synthesis of an inhibitor of the glutamyl binding site. FEBS letters, 1983, Feb-07, Volume: 152, Issue:1 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Carbon-Carbon Ligases; Kinetics; Ligases; Microsomes, Liver; Oligopeptides; Peptide Fragments; Rats; Structure-Activity Relationship; Vitamin K	1983
Radioimmunoassay for the vitamin K-dependent protein of bone and its discovery in plasma. Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:4 Topics: 1-Carboxyglutamic Acid; Animals; Blood; Bone and Bones; Cattle; Humans; Metabolic Clearance Rate; Osteocalcin; Proteins; Radioimmunoassay; Vitamin K	1980
1,25-Dihydroxyvitamin D3 increases synthesis of the vitamin K-dependent bone protein by osteosarcoma cells. The Journal of biological chemistry, 1980, Dec-25, Volume: 255, Issue:24 Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Calcitriol; Cell Line; Dihydroxycholecalciferols; Glutamates; Hydroxycholecalciferols; Kinetics; Neoplasms, Experimental; Osteocalcin; Osteosarcoma; Protein Biosynthesis; Rats; Vitamin K	1980
1,25-dihydroxyvitamin D3 increases serum levels of the vitamin K-dependent bone protein. Biochemical and biophysical research communications, 1981, Apr-15, Volume: 99, Issue:3 Topics: 1-Carboxyglutamic Acid; Animals; Blood Proteins; Bone and Bones; Calcitriol; Dihydroxycholecalciferols; Female; Hydroxycholecalciferols; Male; Osteocalcin; Rats; Sex Factors; Vitamin K	1981
The active form of vitamin D stimulates the synthesis of a vitamin K-dependent bone protein. Nutrition reviews, 1981, Volume: 39, Issue:7 Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Calcitriol; Calcium-Binding Proteins; Dihydroxycholecalciferols; Humans; Hydroxycholecalciferols; Osteocalcin; Vitamin K	1981
Characterization of a proteolytically modified form of human prothorombin. Biochemical and biophysical research communications, 1980, May-30, Volume: 94, Issue:2 Topics: 1-Carboxyglutamic Acid; Barium; Chymotrypsin; Citrates; Factor X; Humans; Molecular Weight; Peptide Hydrolases; Phospholipids; Prothrombin; Vitamin K	1980
A proposed mechanism for vitamin K-dependent gamma-carboxylation of glutamic acid. Nutrition reviews, 1982, Volume: 40, Issue:10 Topics: 1-Carboxyglutamic Acid; Glutamates; Humans; Vitamin K	1982
[Recent discoveries on the biochemical significance of vitamin K and some characteristics of vitamin K dependent proteins]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1981, Nov-01, Volume: 36, Issue:21 Topics: 1-Carboxyglutamic Acid; Adult; Blood Coagulation Factors; Calcification, Physiologic; Humans; Vitamin K; Vitamin K 1	1981
Vitamin K-dependent calcium binding proteins in aortic valve calcification. The Journal of clinical investigation, 1980, Volume: 65, Issue:2 Topics: 1-Carboxyglutamic Acid; Animals; Aortic Valve; Aortic Valve Stenosis; Bioprosthesis; Calcinosis; Calcium-Binding Proteins; Heart Valve Diseases; Humans; Transplantation, Homologous; Vitamin K	1980
Vitamin K-dependent carboxylation of glutamic acid residues to gamma-carboxyglutamic acid in lung microsomes. Archives of biochemistry and biophysics, 1980, Volume: 203, Issue:1 Topics: 1-Carboxyglutamic Acid; Animals; Glutamates; Kinetics; Male; Microsomes; Peptides; Proteins; Rats; Structure-Activity Relationship; Vitamin K; Warfarin	1980
The metabolic role of vitamin K. Federation proceedings, 1980, Volume: 39, Issue:10 Topics: 1-Carboxyglutamic Acid; Animals; Blood Coagulation Factors; Carbon-Carbon Ligases; Kinetics; Ligases; Liver; Microsomes, Liver; NADH, NADPH Oxidoreductases; Proteins; Rats; Vitamin K; Vitamin K Deficiency	1980
Vitamin K intake and osteocalcin levels in women with and without aortic atherosclerosis: a population-based study. Atherosclerosis, 1995, Volume: 116, Issue:1 Topics: 1-Carboxyglutamic Acid; Aged; Aorta, Abdominal; Aortic Diseases; Arteriosclerosis; Body Constitution; Body Mass Index; Calcinosis; Chromatography, Affinity; Cohort Studies; Diet; Durapatite; Female; Humans; Middle Aged; Osteocalcin; Vitamin K; Vitamin K Deficiency	1995
Increased plasma free gamma carboxyglutamic acid levels during deep vein thrombosis and intravascular disseminated coagulation. Thrombosis research, 1994, Feb-15, Volume: 73, Issue:3-4 Topics: 1-Carboxyglutamic Acid; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Carcinoma, Hepatocellular; Chronic Disease; Disseminated Intravascular Coagulation; Female; Hemangioma; Humans; Leg; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Pain; Pulmonary Embolism; Skin Neoplasms; Thrombophlebitis; Vitamin K	1994
Dietary induced subclinical vitamin K deficiency in normal human subjects. The Journal of clinical investigation, 1993, Volume: 91, Issue:4 Topics: 1-Carboxyglutamic Acid; Adult; Aged; Aged, 80 and over; Aging; Antigens; Diet; Factor VII; Female; Humans; Male; Middle Aged; Nutritional Status; Partial Thromboplastin Time; Protein C; Prothrombin Time; Vitamin K; Vitamin K Deficiency	1993
Assessment of dietary phylloquinone intake and vitamin K status in postmenopausal women. European journal of clinical nutrition, 1995, Volume: 49, Issue:11 Topics: 1-Carboxyglutamic Acid; Adult; Aged; Bias; Cross-Sectional Studies; Diet; Diet Records; Fasting; Female; Humans; Middle Aged; Nutrition Assessment; Postmenopause; Reproducibility of Results; Time Factors; Vitamin K	1995
Homology modeling and molecular dynamics simulation of human prothrombin fragment 1. Protein science : a publication of the Protein Society, 1995, Volume: 4, Issue:11 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Blood Coagulation Factors; Calcium; Cattle; Crystallography, X-Ray; Humans; Hydrogen Bonding; Kringles; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Phospholipids; Protein Precursors; Protein Structure, Secondary; Prothrombin; Sequence Homology; Vitamin K	1995
Comparison of biochemical indexes for assessing vitamin K nutritional status in a healthy adult population. The American journal of clinical nutrition, 1996, Volume: 63, Issue:4 Topics: 1-Carboxyglutamic Acid; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Boston; Creatinine; Female; Humans; Male; Menopause; Middle Aged; Nutritional Status; Osteocalcin; Prothrombin; Sex Characteristics; Vitamin K; Vitamin K 1	1996
Assessment of vitamin K status in human subjects administered "minidose" warfarin. The American journal of clinical nutrition, 1996, Volume: 64, Issue:6 Topics: 1-Carboxyglutamic Acid; Adult; Aged; Anticoagulants; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Incidence; Male; Middle Aged; Osteocalcin; Prothrombin; Thrombosis; Vitamin K; Vitamin K 1; Warfarin	1996
Nutritional vitamin K-intake and urinary gamma-carboxyglutamate excretion in the rat. Biochimica et biophysica acta, 1997, Feb-11, Volume: 1334, Issue:1 Topics: 1-Carboxyglutamic Acid; 4-Hydroxycoumarins; Animals; Anticoagulants; Diet; Dose-Response Relationship, Drug; Male; Prothrombin; Rats; Vitamin K; Vitamin K Deficiency	1997
Identification of a vitamin K-dependent carboxylase in the venom duct of a Conus snail. FEBS letters, 1997, Apr-21, Volume: 407, Issue:1 Topics: 1-Carboxyglutamic Acid; Animals; Carbon-Carbon Ligases; Dose-Response Relationship, Drug; Ligases; Microsomes; Mollusk Venoms; Protein Processing, Post-Translational; Snails; Species Specificity; Substrate Specificity; Vitamin K	1997
Requirement of gamma-carboxyglutamic acid residues for the biological activity of Gas6: contribution of endogenous Gas6 to the proliferation of vascular smooth muscle cells. The Biochemical journal, 1997, Apr-15, Volume: 323 ( Pt 2) Topics: 1-Carboxyglutamic Acid; Animals; Anticoagulants; Blotting, Western; Calcium; Cell Division; Cells, Cultured; CHO Cells; Cricetinae; Epidermal Growth Factor; Intercellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Proteins; Rats; Structure-Activity Relationship; Thrombin; Vitamin K; Warfarin	1997
The propeptide of the vitamin K-dependent carboxylase substrate accelerates formation of the gamma-glutamyl carbanion intermediate. Biochemistry, 1997, May-27, Volume: 36, Issue:21 Topics: 1-Carboxyglutamic Acid; Calibration; Carbon Dioxide; Carbon Radioisotopes; Carbon-Carbon Ligases; Catalysis; Kinetics; Ligases; Protein Precursors; Sodium Bicarbonate; Substrate Specificity; Tritium; Vitamin K	1997
Primary structure and tissue distribution of two novel proline-rich gamma-carboxyglutamic acid proteins. Proceedings of the National Academy of Sciences of the United States of America, 1997, Aug-19, Volume: 94, Issue:17 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA, Complementary; Humans; Molecular Sequence Data; Peptides; Proline; Proline-Rich Protein Domains; Proteins; Sequence Alignment; Sequence Analysis; Vitamin K	1997
Evidence for modulation of osteocalcin containing gamma-carboxyglutamic acid residues synthesis by insulin-like growth factor-I and vitamin K2 in human osteosarcoma cell line MG-63. European journal of endocrinology, 1998, Volume: 138, Issue:4 Topics: 1-Carboxyglutamic Acid; Cycloheximide; Humans; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor I; Osteoblasts; Osteocalcin; Osteosarcoma; Protein Synthesis Inhibitors; RNA, Messenger; Stimulation, Chemical; Tumor Cells, Cultured; Vitamin K; Warfarin	1998
Role of the propeptide and gamma-glutamic acid domain of factor IX for in vitro carboxylation by the vitamin K-dependent carboxylase. Biochemistry, 1998, Sep-22, Volume: 37, Issue:38 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Binding, Competitive; Carbon-Carbon Ligases; Cattle; CHO Cells; Cricetinae; Factor IX; Humans; Kinetics; Molecular Sequence Data; Peptides; Protein Precursors; Protein Structure, Tertiary; Recombinant Fusion Proteins; Vitamin K	1998
Gender differences in hepatic phylloquinone and menaquinones in the vitamin K-deficient and -supplemented rat. Biochimica et biophysica acta, 1999, Jan-04, Volume: 1426, Issue:1 Topics: 1-Carboxyglutamic Acid; Animals; Chromatography, High Pressure Liquid; Diet; Humans; Liver; Male; Prothrombin; Rats; Rats, Sprague-Dawley; Sex Factors; Vitamin K; Vitamin K 1; Vitamin K 2; Vitamin K Deficiency	1999
Matrix GLA protein is a developmental regulator of chondrocyte mineralization and, when constitutively expressed, blocks endochondral and intramembranous ossification in the limb. The Journal of cell biology, 1999, Nov-29, Volume: 147, Issue:5 Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Calcification, Physiologic; Calcium-Binding Proteins; Cells, Cultured; Chick Embryo; Chondrocytes; Extracellular Matrix Proteins; Gene Expression Regulation, Developmental; Limb Buds; Matrix Gla Protein; Microscopy, Electron, Scanning; Minerals; Osteogenesis; Vitamin K; Warfarin	1999
Identification and purification of vitamin K-dependent proteins and peptides with monoclonal antibodies specific for gamma -carboxyglutamyl (Gla) residues. The Journal of biological chemistry, 2000, Jun-30, Volume: 275, Issue:26 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Monoclonal; Blood Coagulation Factor Inhibitors; Blood Coagulation Factors; Blotting, Western; Calcium-Binding Proteins; Cattle; Cell Line; Chromatography, Affinity; Conotoxins; Enzyme-Linked Immunosorbent Assay; Epitopes; Fluorescent Antibody Technique; Humans; Molecular Sequence Data; Mutagenesis; Peptides; Protein Binding; Recombinant Proteins; Sequence Homology, Amino Acid; Snake Venoms; Surface Plasmon Resonance; Time Factors; Vitamin K	2000
Determination of the N-terminal amino acid sequence of the purified prothrombin from a patient with liver cirrhosis. Thrombosis research, 2000, Aug-01, Volume: 99, Issue:3 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Ascitic Fluid; Glutamic Acid; Hemorrhagic Disorders; Humans; Liver Cirrhosis; Molecular Weight; Protein Processing, Post-Translational; Prothrombin; Prothrombin Time; Vitamin K	2000
Synthesis of gamma-carboxylated polypeptides by alpha-cells of the pancreatic islets. Biochemical and biophysical research communications, 2001, May-04, Volume: 283, Issue:2 Topics: 1-Carboxyglutamic Acid; Animals; Antibodies, Monoclonal; Clone Cells; Glucagonoma; Humans; Immunohistochemistry; Insulinoma; Islets of Langerhans; Mice; Pancreatic Neoplasms; Protein Biosynthesis; Protein S; Proteins; Prothrombin; Vitamin K	2001
The effect of microgravity on plasma-osteocalcin. Advances in space research : the official journal of the Committee on Space Research (COSPAR), 1986, Volume: 6, Issue:12 Topics: 1-Carboxyglutamic Acid; Adult; Aerospace Medicine; Aged; Bone and Bones; Humans; Middle Aged; Osteocalcin; Osteoporosis; Space Flight; Vitamin K; Vitamin K 1; Weightlessness; Weightlessness Countermeasures	1986
Bone markers during a 6-month space flight: effects of vitamin K supplementation. Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology, 1998, Volume: 5, Issue:2 Topics: 1-Carboxyglutamic Acid; Adult; Aerospace Medicine; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Bone Development; Bone Resorption; Calcium; Humans; Osteocalcin; Osteoporosis; Parathyroid Hormone; Space Flight; Vitamin K; Vitamin K 1; Weightlessness; Weightlessness Countermeasures	1998
Detection of vitamin K-dependent proteins in venoms with a monoclonal antibody specific for gamma-carboxyglutamic acid. Toxicon : official journal of the International Society on Toxinology, 2002, Volume: 40, Issue:4 Topics: 1-Carboxyglutamic Acid; Amphibian Venoms; Animals; Antibodies, Monoclonal; Anura; Biological Assay; Blood Proteins; Blotting, Western; Elapid Venoms; Factor Xa; Fluorescent Antibody Technique; Mollusk Venoms; Peptides; Salivary Glands; Snails; Snakes; Vitamin K	2002
The induction of c-fos mRNA expression by mechanical stress in human periodontal ligament cells. Archives of oral biology, 2002, Volume: 47, Issue:6 Topics: 1-Carboxyglutamic Acid; Alkaline Phosphatase; Bite Force; Bone and Bones; Calcium-Binding Proteins; Cell Culture Techniques; Collagen Type I; Collagen Type III; Extracellular Matrix Proteins; Fibroblasts; Gene Expression Regulation; Humans; Mastication; Matrix Gla Protein; Osteocalcin; Osteonectin; Osteopontin; Periodontal Ligament; Phosphoproteins; Proto-Oncogene Proteins c-fos; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sialoglycoproteins; Stress, Mechanical; Time Factors; Vitamin K; Weight-Bearing	2002
Vitamin K-dependent protein S localizing complement regulator C4b-binding protein to the surface of apoptotic cells. Journal of immunology (Baltimore, Md. : 1950), 2002, Sep-01, Volume: 169, Issue:5 Topics: 1-Carboxyglutamic Acid; Annexin A5; Apoptosis; Binding, Competitive; Cell Membrane; Complement C4b; Complement Inactivator Proteins; Glycoproteins; Humans; Jurkat Cells; Macromolecular Substances; Phospholipids; Protein Binding; Protein S; Protein Structure, Tertiary; Receptors, Complement; Vitamin K	2002
Gas6 binding to photoreceptor outer segments requires gamma-carboxyglutamic acid (Gla) and Ca(2+) and is required for OS phagocytosis by RPE cells in vitro. Experimental eye research, 2002, Volume: 75, Issue:4 Topics: 1-Carboxyglutamic Acid; Animals; Calcium; Cells, Cultured; Fluorescent Antibody Technique; Immunoblotting; Intercellular Signaling Peptides and Proteins; Phagocytosis; Pigment Epithelium of Eye; Protein Denaturation; Proteins; Rats; Rod Cell Outer Segment; Vitamin K	2002
Expression and characterization of recombinant vitamin K-dependent gamma-glutamyl carboxylase from an invertebrate, Conus textile. European journal of biochemistry, 2002, Volume: 269, Issue:24 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Blood Coagulation; Blotting, Western; Carbon-Carbon Ligases; Cell Line; Cloning, Molecular; COS Cells; DNA, Complementary; Dose-Response Relationship, Drug; Genetic Vectors; Humans; Insecta; Kinetics; Microsomes; Molecular Sequence Data; Mollusca; Open Reading Frames; Plasmids; Protein Processing, Post-Translational; Recombinant Proteins; Sequence Homology, Amino Acid; Vitamin K	2002
Glucocorticoid effects on vitamin K-dependent carboxylase activity and matrix Gla protein expression in rat lung. American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 285, Issue:3 Topics: 1-Carboxyglutamic Acid; Adrenalectomy; Animals; Calcium-Binding Proteins; Carbon-Carbon Ligases; Cells, Cultured; Dexamethasone; Extracellular Matrix Proteins; Female; Glucocorticoids; Lung; Matrix Gla Protein; Microsomes; Pregnancy; Rats; Rats, Wistar; Respiratory Mucosa; Vitamin K	2003
Identification of a gene encoding a typical gamma-carboxyglutamic acid domain in the tunicate Halocynthia roretzi. Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:1 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Base Sequence; Blood Coagulation Factors; DNA, Complementary; In Situ Hybridization; Molecular Sequence Data; Oogenesis; Peptides; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; Tissue Distribution; Transcription, Genetic; Urochordata; Vitamin K	2003
Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins. Nature structural biology, 2003, Volume: 10, Issue:9 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Arginine; Binding Sites; Blood Coagulation; Calcium; Cattle; Cell Membrane; Crystallography, X-Ray; Ions; Lysophospholipids; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptides; Protein Binding; Protein Structure, Tertiary; Prothrombin; Vitamin K	2003
Binding of the factor IX gamma-carboxyglutamic acid domain to the vitamin K-dependent gamma-glutamyl carboxylase active site induces an allosteric effect that may ensure processive carboxylation and regulate the release of carboxylated product. The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8 Topics: 1-Carboxyglutamic Acid; Allosteric Site; Anisotropy; Binding Sites; Carbon-Carbon Ligases; Carboxylic Acids; Dose-Response Relationship, Drug; Factor IX; Glutamic Acid; Humans; Kinetics; Protein Binding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Substrate Specificity; Time Factors; Vitamin K	2004
Vitamin K: lessons from the past. Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:12 Topics: 1-Carboxyglutamic Acid; Animals; Anticoagulants; Bone and Bones; Dietary Supplements; Humans; Liver; Osteocalcin; Risk; Thrombosis; Vitamin K	2004
From gamma-carboxy-glutamate to protein C. Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:12 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Anticoagulants; Biochemistry; Blood Coagulation; Calcium; Dicumarol; History, 20th Century; Humans; Models, Molecular; Molecular Sequence Data; Oligopeptides; Protein Binding; Protein C; Protein Conformation; Prothrombin; Vitamin K	2006
Vitamin K-dependent proteins in Ciona intestinalis, a basal chordate lacking a blood coagulation cascade. Proceedings of the National Academy of Sciences of the United States of America, 2006, Oct-24, Volume: 103, Issue:43 Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Blood Coagulation; Ciona intestinalis; Conserved Sequence; Gene Expression; In Situ Hybridization; Molecular Sequence Data; Proteins; Sequence Alignment; Vitamin K	2006
Quantum chemical study of the mechanism of action of vitamin K carboxylase (VKC). IV. Intermediates and transition states. The journal of physical chemistry. A, 2007, Aug-09, Volume: 111, Issue:31 Topics: 1-Carboxyglutamic Acid; Carbon Dioxide; Carbon-Carbon Ligases; Epoxy Compounds; Hydroquinones; Models, Biological; Molecular Structure; Quantum Theory; Vitamin K	2007
Post-translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification. Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:12 Topics: 1-Carboxyglutamic Acid; Adolescent; Adult; Amino Acid Sequence; Calcinosis; Calcium; Calcium-Binding Proteins; Cell Membrane; Cells, Cultured; Extracellular Matrix Proteins; Female; Humans; Male; Matrix Gla Protein; Middle Aged; Molecular Sequence Data; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Serine; Transport Vesicles; Vitamin K; Vitamin K 1; Warfarin	2007
Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by {gamma}-carboxylation-dependent and -independent mechanisms. American journal of physiology. Cell physiology, 2009, Volume: 297, Issue:6 Topics: 1-Carboxyglutamic Acid; Calcification, Physiologic; Cell Differentiation; Cell Proliferation; Cells, Cultured; Humans; Metabolism; Osteoblasts; Osteocytes; Phenotype; Vitamin K; Vitamin K 1; Vitamin K 2; Vitamin K 3; Warfarin	2009
Expanding the functional spectrum of vitamin K in bone. Focus on: "Vitamin K promotes mineralization, osteoblast to osteocyte transition, and an anti-catabolic phenotype by {gamma}-carboxylation-dependent and -independent mechanisms". American journal of physiology. Cell physiology, 2009, Volume: 297, Issue:6 Topics: 1-Carboxyglutamic Acid; Animals; Bone and Bones; Calcification, Physiologic; Cell Differentiation; Humans; Metabolism; Osteoblasts; Osteocytes; Phenotype; Vitamin K	2009
Vitamin K suppresses the lipopolysaccharide-induced expression of inflammatory cytokines in cultured macrophage-like cells via the inhibition of the activation of nuclear factor κB through the repression of IKKα/β phosphorylation. The Journal of nutritional biochemistry, 2010, Volume: 21, Issue:11 Topics: 1-Carboxyglutamic Acid; Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cytokines; Humans; I-kappa B Kinase; Interleukin-6; Lipopolysaccharides; Mice; Mice, Inbred C57BL; NF-kappa B; Phosphorylation; RNA, Messenger; Vitamin K	2010
Investigation and identification of protein γ-glutamyl carboxylation sites. BMC bioinformatics, 2011, Volume: 12 Suppl 13 Topics: 1-Carboxyglutamic Acid; Humans; Protein Processing, Post-Translational; Proteins; Substrate Specificity; Support Vector Machine; Vitamin K	2011
Quantifying vitamin K-dependent holoprotein compaction caused by differential γ-carboxylation using high-pressure size exclusion chromatography. Analytical biochemistry, 2015, Jun-15, Volume: 479 Topics: 1-Carboxyglutamic Acid; Binding Sites; Calcium; Cations, Divalent; Chromatography, Gel; Factor IX; Humans; Magnesium; Models, Molecular; Protein Conformation; Recombinant Proteins; Vitamin K	2015
Deeper understanding of carboxylase. Blood, 2016, Apr-14, Volume: 127, Issue:15 Topics: 1-Carboxyglutamic Acid; Glutamic Acid; Hemorrhage; Humans; Mutation; Phenotype; Vitamin K	2016
Carboxylative efficacy of trans and cis MK7 and comparison with other vitamin K isomers. BioFactors (Oxford, England), 2022, Volume: 48, Issue:5 Topics: 1-Carboxyglutamic Acid; Humans; Vitamin K; Vitamin K 1; Vitamin K 2; Warfarin	2022