1-butyl-3-methylimidazolium and diacetyldichlorofluorescein

1-butyl-3-methylimidazolium has been researched along with diacetyldichlorofluorescein* in 1 studies

Other Studies

1 other study(ies) available for 1-butyl-3-methylimidazolium and diacetyldichlorofluorescein

Article	Year
Measurement of creatinine in human plasma using a functional porous polymer structure sensing motif. International journal of nanomedicine, 2015, Volume: 10 Spec Iss In this study, a new method for detecting creatinine was developed. This novel sensor comprised of two ionic liquids, poly-lactic-co-glycolic acid (PLGA) and 1-butyl-3-methylimidazolium (BMIM) chloride, in the presence of 2',7'-dichlorofluorescein diacetate (DCFH-DA). PLGA and BMIM chloride formed a functional porous polymer structure (FPPS)-like structure. Creatinine within the FPPS rapidly hydrolyzed and released OH(-), which in turn converted DCFH-DA to DCFH, developing an intense green color or green fluorescence. The conversion of DCFH to DCF(+) resulted in swelling of FPPS and increased solubility. This DCF(+)-based sensor could detect creatinine levels with detection limit of 5 µM and also measure the creatinine in blood. This novel method could be used in diagnostic applications for monitoring individuals with renal dysfunction. Topics: Biosensing Techniques; Creatinine; Fluoresceins; Fluorescent Dyes; Humans; Imidazoles; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer	2015

Article

Year

Measurement of creatinine in human plasma using a functional porous polymer structure sensing motif.

International journal of nanomedicine, 2015, Volume: 10 Spec Iss

In this study, a new method for detecting creatinine was developed. This novel sensor comprised of two ionic liquids, poly-lactic-co-glycolic acid (PLGA) and 1-butyl-3-methylimidazolium (BMIM) chloride, in the presence of 2',7'-dichlorofluorescein diacetate (DCFH-DA). PLGA and BMIM chloride formed a functional porous polymer structure (FPPS)-like structure. Creatinine within the FPPS rapidly hydrolyzed and released OH(-), which in turn converted DCFH-DA to DCFH, developing an intense green color or green fluorescence. The conversion of DCFH to DCF(+) resulted in swelling of FPPS and increased solubility. This DCF(+)-based sensor could detect creatinine levels with detection limit of 5 µM and also measure the creatinine in blood. This novel method could be used in diagnostic applications for monitoring individuals with renal dysfunction.

Topics: Biosensing Techniques; Creatinine; Fluoresceins; Fluorescent Dyes; Humans; Imidazoles; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2015