1-benzylimidazole has been researched along with ketoconazole in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| James, MO; Sloan, KB | 1 |
| Kuntz, ID; Ortiz de Montellano, PR; Verras, A | 1 |
| Ahmed, S; Dhanani, S; Owen, CP; Patel, CH; Shahid, I | 1 |
| Ahmed, S; Dhanani, S; Owen, CP; Patel, CH | 1 |
| Ahmed, S; Lee, WY; Owen, CP; Shahid, I | 1 |
| Hartmann, RW; Hille, UE; Vock, CA; Zimmer, C | 1 |
| Bron, S; Chambon, M; Colau, D; Majjigapu, SR; Michielin, O; Pilotte, L; Röhrig, UF; Turcatti, G; Van den Eynde, BJ; Vogel, P; Zoete, V | 1 |
| Jernerén, F; Oliw, EH | 1 |
| Bureik, M; Durairaj, P; Fan, L; Jie, Z; Sharma, SS | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
10 other study(ies) available for 1-benzylimidazole and ketoconazole
| Article | Year |
|---|---|
Structural features of imidazole derivatives that enhance styrene oxide hydrolase activity in rat hepatic microsomes.
Topics: Animals; Antifungal Agents; Enzyme Activation; Epoxide Hydrolases; Imidazoles; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1985 |
Computer-assisted design of selective imidazole inhibitors for cytochrome p450 enzymes.
Topics: Computer-Aided Design; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Databases, Factual; Drug Design; Enzyme Inhibitors; Imidazoles; Mutation; Quantitative Structure-Activity Relationship; Spectrophotometry, Ultraviolet | 2004 |
Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).
Topics: Enzyme Inhibitors; Imidazoles; Models, Molecular; Steroid 17-alpha-Hydroxylase | 2006 |
Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Imidazoles; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Progesterone | 2006 |
Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as potent inhibitors of 17alpha-hydroxylase/17,20-lyase (P45017alpha) derived from rat testicular microsomes.
Topics: Animals; Enzyme Inhibitors; Imidazoles; Inhibitory Concentration 50; Male; Microsomes; Models, Molecular; Rats; Steroid 17-alpha-Hydroxylase; Testis | 2010 |
First Selective CYP11B1 Inhibitors for the Treatment of Cortisol-Dependent Diseases.
Topics: | 2011 |
Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
Topics: Animals; Antifungal Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Molecular Dynamics Simulation; Molecular Structure; Structure-Activity Relationship | 2014 |
The fatty acid 8,11-diol synthase of Aspergillus fumigatus is inhibited by imidazole derivatives and unrelated to PpoB.
Topics: Aspergillus fumigatus; Chromatography, Liquid; Fungal Proteins; Imidazoles; Ketoconazole; Miconazole; Oxygenases; Stereoisomerism; Tandem Mass Spectrometry | 2012 |
Identification of new probe substrates for human CYP20A1.
Topics: Cytochrome P-450 Enzyme System; Humans; Imidazoles; Ketoconazole; Letrozole; Molecular Structure; Substrate Specificity | 2020 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |