Page last updated: 2024-08-21

1-aminopyrene and 1-nitropyrene

1-aminopyrene has been researched along with 1-nitropyrene in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199017 (58.62)18.7374
1990's7 (24.14)18.2507
2000's1 (3.45)29.6817
2010's3 (10.34)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Claxton, LD; George, SE; King, LC; Kohan, MJ; Lewtas, J1
Hayakawa, K; Imaizumi, N; Miyazaki, M; Suzuki, Y1
Arena, AR; Belisario, MA; Pecce, R; Scopacasa, F; Staiano, N1
Hsu, IC; Synder, S; Trump, BF1
Zytkovicz, TH1
Batmanghelich, S; Edwards, MJ; Edwards, S; Parry, JM; Smith, K1
Lafi, A; Parry, JM1
DiBello, J; el-Bayoumy, K; Hecht, SS; Johnson, B; Little, P; Rivenson, A1
Nickols, JW; Okinaka, RT; Strniste, GF; Whaley, TW1
Cerniglia, CE; Federle, TW; Manning, BW1
Batmanghelich, S; Edwards, MJ; Parry, JM; Smith, K1
Beland, FA; Flammang, TJ; Howard, PC1
Ayres, PH; Bond, JA; Sun, JD1
Beland, FA; Cerniglia, CE; Howard, PC1
Ball, J; Salmeen, I; Zacmanidis, P1
El-Bayoumy, K; Hecht, SS1
El-Bayoumy, K; Hecht, SS; Louis, YM; Reddy, B; Sharma, C1
Nachtman, JP; Wei, ET1
Andrews, P; Lu, C; McCalla, DR; McCarry, BE; Messier, F; Quilliam, MA1
Bos, RP; Martens, MH; Scheepers, PT; Thuis, HJ1
King, LC; Lewtas, J1
Belisario, MA; Garofalo, A; Malorni, A; Pecce, R; Sannolo, N1
Kitamura, S; Tatsumi, K1
Evans, DH; Guengerich, FP; Henry, T; Josephy, PD; Williamson, V1
Guengerich, FP; Hatanaka, N; Nakajima, M; Oda, Y; Yamazaki, H; Yokoi, T1
Holme, JA; Låg, M; Refsnes, M; Schwarze, PE; Øvrevik, J2
Becher, R; Gilot, D; Holme, JA; Låg, M; Lagadic-Gossmann, D; Lecureur, V; Refsnes, M; Schwarze, PE; Skuland, T; Øvrevik, J1
Bafana, A; Farooqui, MO; Kannan, K; Middey, A; Naoghare, P; Pakade, Y; Sivanesan, S; Vanisree, AJ; Wadikar, DL1

Other Studies

29 other study(ies) available for 1-aminopyrene and 1-nitropyrene

ArticleYear
Metabolism of 1-nitropyrene by human, rat, and mouse intestinal flora: mutagenicity of isolated metabolites by direct analysis of HPLC fractions with a microsuspension reverse mutation assay.
    Journal of toxicology and environmental health, 1990, Volume: 31, Issue:3

    Topics: Animals; Bacteria; Biotransformation; Chromatography, High Pressure Liquid; Feces; Humans; Intestines; Male; Mice; Mutagenicity Tests; Mutagens; Pyrenes; Rats

1990
Determination of nitrated pyrenes and their derivatives by high performance liquid chromatography with chemiluminescence detection after online electrochemical reduction.
    Biomedical chromatography : BMC, 1990, Volume: 4, Issue:3

    Topics: Chromatography, High Pressure Liquid; Electrochemistry; Luminescent Measurements; Mutagens; Nitrate Reductase; Nitrate Reductases; Polycyclic Compounds; Pyrenes

1990
Characterization of the induction of rat hepatic microsomal drug-metabolizing enzymes by 1-nitropyrene metabolites, 1-aminopyrene and N-acetylaminopyrene.
    Toxicology, 1989, Jul-03, Volume: 57, Issue:1

    Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; In Vitro Techniques; Male; Microsomes, Liver; Mutagens; Pyrenes; Rats; Rats, Inbred Strains; Substrate Specificity

1989
Comparison of metabolic activation of carcinogens in human, rat, and hamster hepatocytes.
    Mutation research, 1987, Volume: 182, Issue:1

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cells, Cultured; Cricetinae; Fluorenes; Humans; Liver; Pyrenes; Rats

1987
The 4-5S carcinogen binding protein binds 1-aminopyrene, 1-nitropyrene and (+)-benzo[a]pyrenediolepoxide and is found in 12 tissues of the DBA/2J mouse.
    Toxicology letters, 1987, Volume: 39, Issue:2-3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Binding, Competitive; Carcinogens; Carrier Proteins; Dihydroxydihydrobenzopyrenes; Female; Liver; Male; Mice; Mice, Inbred DBA; Pyrenes

1987
The induction of DNA adducts in mammalian cells exposed to 1-nitropyrene and its nitro-reduced derivatives.
    Mutagenesis, 1986, Volume: 1, Issue:5

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; DNA; Fibroblasts; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mutagens; Pyrenes; Spectrophotometry

1986
Chromosome aberrations induced by nitro-, nitroso- and aminopyrenes in cultured Chinese hamster cells.
    Mutagenesis, 1987, Volume: 2, Issue:1

    Topics: Animals; Cell Line; Chromatids; Chromosome Aberrations; Mitotic Index; Mutagenicity Tests; Mutagens; Pyrenes

1987
Comparative tumorigenicity of 1-nitropyrene, 1-nitrosopyrene, and 1-aminopyrene administered by gavage to Sprague-Dawley rats.
    Cancer research, 1988, Aug-01, Volume: 48, Issue:15

    Topics: Adenocarcinoma; Animals; Animals, Newborn; Female; Male; Mammary Neoplasms, Experimental; Pyrenes; Rats; Rats, Inbred Strains

1988
1-Nitropyrene: a mutagenic product induced by the action of near ultraviolet light on 1-aminopyrene.
    Mutation research, 1986, Volume: 173, Issue:2

    Topics: Chromatography, High Pressure Liquid; Environmental Pollutants; Mass Spectrometry; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Pyrenes; Salmonella typhimurium; Ultraviolet Rays

1986
Biotransformation of 1-nitropyrene to 1-aminopyrene and N-formyl-1-aminopyrene by the human intestinal microbiota.
    Journal of toxicology and environmental health, 1986, Volume: 18, Issue:3

    Topics: Chromatography, High Pressure Liquid; Humans; Inactivation, Metabolic; Intestines; Mass Spectrometry; Mutagenicity Tests; Oxidation-Reduction; Pyrenes; Salmonella typhimurium

1986
Toxicity and DNA damage induced by 1-nitropyrene and its derivatives in Chinese hamster lung fibroblasts.
    Mutation research, 1986, Volume: 163, Issue:1

    Topics: Animals; Cell Line; Cell Survival; Cricetinae; DNA; Dose-Response Relationship, Drug; Nitroso Compounds; Pyrenes

1986
Comparison of the in vitro and in vivo hepatic metabolism of the carcinogen 1-nitropyrene.
    Carcinogenesis, 1985, Volume: 6, Issue:2

    Topics: Animals; Bile; Carcinogens; Glucuronates; In Vitro Techniques; Liver; Male; Phenobarbital; Pyrenes; Rats; Rats, Inbred Strains; Tritium

1985
Contribution of intestinal microfloral metabolism to the total macromolecular covalent binding of 1-nitro-pyrene in the lung and liver of the rat.
    Toxicology, 1985, Volume: 36, Issue:2-3

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Carbon Radioisotopes; Intestines; Liver; Lung; Macromolecular Substances; Male; Pyrenes; Rats; Rats, Inbred F344

1985
Reduction of the carcinogen 1-nitropyrene to 1-aminopyrene by rat intestinal bacteria.
    Carcinogenesis, 1983, Volume: 4, Issue:8

    Topics: Anaerobiosis; Animals; Bacteria; Biotransformation; Carcinogens; Intestines; Mutagenicity Tests; Mutagens; Mutation; Pyrenes; Rats; Salmonella typhimurium; Species Specificity

1983
1-Nitropyrene reduction by Salmonella typhimurium, V79 Chinese hamster and primary rat liver cells.
    Mutation research, 1983, Volume: 122, Issue:1

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; Liver; Mutagens; Pyrenes; Rats; Rats, Inbred Strains; Salmonella typhimurium

1983
Identification and mutagenicity of metabolites of 1-nitropyrene formed by rat liver.
    Cancer research, 1983, Volume: 43, Issue:7

    Topics: Animals; Aroclors; Carcinogens; Cell Fractionation; Chromatography, High Pressure Liquid; In Vitro Techniques; Liver; Mutagenicity Tests; Oxidation-Reduction; Pyrenes; Rats; Spectrum Analysis

1983
The role of intestinal microflora in the metabolic reduction of 1-nitropyrene to 1-aminopyrene in conventional and germfree rats and in humans.
    Cancer letters, 1983, Volume: 19, Issue:3

    Topics: Anaerobiosis; Animals; Bacteria; Biotransformation; Feces; Germ-Free Life; Humans; Intestines; Male; Oxidation-Reduction; Pyrenes; Rats; Rats, Inbred F344

1983
Evidence for enzymatic reduction of 1-nitropyrene by rat liver fractions.
    Experientia, 1982, Jul-15, Volume: 38, Issue:7

    Topics: Animals; Cytosol; Flavin Mononucleotide; Liver; Male; Microsomes, Liver; Mutagens; NADP; Oxidation-Reduction; Pyrenes; Rats; Rats, Inbred Strains

1982
Metabolism of 1-nitropyrene and formation of DNA adducts in Salmonella typhimurium.
    Carcinogenesis, 1981, Volume: 2, Issue:10

    Topics: Biotransformation; Chromatography, High Pressure Liquid; DNA, Bacterial; Hydrolysis; Mass Spectrometry; Nitro Compounds; Nitroreductases; Oxidoreductases; Pyrenes; Salmonella typhimurium

1981
Assessment of occupational exposure to diesel exhaust. The use of an immunoassay for the determination of urinary metabolites of nitroarenes and polycyclic aromatic hydrocarbons.
    Toxicology letters, 1994, Volume: 72, Issue:1-3

    Topics: Antibodies; Enzyme-Linked Immunosorbent Assay; Humans; Immunoassay; Male; Nitro Compounds; Occupational Exposure; Polycyclic Compounds; Pyrenes; Vehicle Emissions

1994
An evaluation of the comparative metabolism and kinetics of 1-nitropyrene by rabbit, rat, and hamster tracheal epithelial cells.
    Toxicology and applied pharmacology, 1993, Volume: 122, Issue:1

    Topics: Animals; Biotransformation; Cell Count; Cells, Cultured; Cricetinae; Epithelial Cells; Epithelium; Kinetics; Oxidation-Reduction; Pyrenes; Rabbits; Rats; Species Specificity; Trachea

1993
Erythrocyte enzymes catalyze 1-nitropyrene and 3-nitrofluoranthene nitroreduction.
    Toxicology, 1996, Apr-15, Volume: 108, Issue:1-2

    Topics: Biotransformation; Blood Proteins; Catalysis; Chromatography, High Pressure Liquid; Erythrocytes; Fluorenes; Hemoglobins; Humans; Hydrolysis; In Vitro Techniques; Mutagens; Nitroreductases; Protein Binding; Pyrenes

1996
1-Nitropyrene-metabolizing activities of fish liver preparations.
    Bulletin of environmental contamination and toxicology, 1997, Volume: 58, Issue:3

    Topics: Acetylation; Animals; Chromatography, High Pressure Liquid; Cytosol; Fishes; Microsomes, Liver; Mutagens; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Pyrenes; Pyrimidines; Spectrophotometry, Ultraviolet

1997
Plasmid-mediated expression of the UmuDC mutagenesis proteins in an Escherichia coli strain engineered for human cytochrome P450 1A2-catalyzed activation of aromatic amines.
    Mutation research, 1999, Oct-19, Volume: 429, Issue:2

    Topics: Amines; Bacterial Proteins; Cytochrome P-450 CYP1A2; DNA-Directed DNA Polymerase; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Humans; Mutagenesis; Mutagenicity Tests; Mutagens; Plasmids; Pyrenes; Quinolines

1999
Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay.
    Mutation research, 2001, Oct-18, Volume: 497, Issue:1-2

    Topics: Acetyltransferases; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Escherichia coli; Humans; In Vitro Techniques; Microsomes, Liver; Mutagens; NADPH-Ferrihemoprotein Reductase; Pyrenes; Recombinant Proteins; Salmonella typhimurium; SOS Response, Genetics

2001
Differential chemokine induction by 1-nitropyrene and 1-aminopyrene in bronchial epithelial cells: importance of the TACE/TGF-α/EGFR-pathway.
    Environmental toxicology and pharmacology, 2013, Volume: 35, Issue:2

    Topics: ADAM Proteins; ADAM17 Protein; Bronchi; Cells, Cultured; Chemokines; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Humans; Imidazoles; Interleukin-8; Pyrenes; Pyridines; Signal Transduction; Transforming Growth Factor alpha

2013
Mechanisms of chemokine responses by polycyclic aromatic hydrocarbons in bronchial epithelial cells: sensitization through toll-like receptor-3 priming.
    Toxicology letters, 2013, May-23, Volume: 219, Issue:2

    Topics: Blotting, Western; Bronchi; Cell Line; Chemokine CCL5; Chemokines; Cytochrome P-450 Enzyme System; Epithelial Cells; Flow Cytometry; Gene Silencing; Humans; Interleukin-8; Poly I-C; Polycyclic Aromatic Hydrocarbons; Pyrenes; Reactive Oxygen Species; RNA, Small Interfering; Toll-Like Receptor 3

2013
AhR and Arnt differentially regulate NF-κB signaling and chemokine responses in human bronchial epithelial cells.
    Cell communication and signaling : CCS, 2014, Jul-24, Volume: 12

    Topics: Air Pollutants; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzoflavones; Bronchi; Cell Line, Tumor; Chemokine CCL5; Epithelial Cells; Humans; Interleukin-8; NF-kappa B; Phosphorylation; Poly I-C; Pyrenes; Receptors, Aryl Hydrocarbon; Serine; Signal Transduction; Tumor Necrosis Factor-alpha

2014
Assessment of occupational exposure to diesel particulate matter through evaluation of 1-nitropyrene and 1-aminopyrene in surface coal miners, India.
    Environmental monitoring and assessment, 2021, May-17, Volume: 193, Issue:6

    Topics: Air Pollutants, Occupational; Coal; Coal Mining; Cohort Studies; Environmental Monitoring; Humans; India; Miners; Occupational Exposure; Particulate Matter; Pyrenes; Vehicle Emissions

2021