1-amino-1,3-dicarboxycyclopentane has been researched along with glycine in 193 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 148 (76.68) | 18.2507 |
| 2000's | 43 (22.28) | 29.6817 |
| 2010's | 2 (1.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
| Hayashi, M; Hirose, E; Ito, I; Kohda, A; Mitsunaga, S; Sugiyama, H; Tanabe, S | 1 |
| Gähwiler, BH; Gerber, U | 1 |
| Baker, SR; Goldsworthy, JS; Johnson, BG; Salhoff, CR; Schoepp, DD; Wright, RA | 1 |
| Bernardi, G; Bonci, A; Calabresi, P; Mercuri, NB; Stratta, F | 1 |
| Glaum, SR; Miller, RJ; Sunter, DC; Udvarhelyi, PM; Watkins, JC | 1 |
| Battaglia, G; Bruno, V; Copani, A; Nicoletti, F; Raffaele, R; Shinozaki, H | 1 |
| Cavanni, P; Eistetter, H; Ferraguti, F; Ratti, E; Salvagno, C; Trist, DG | 1 |
| Eaton, SA; Salt, TE | 1 |
| Birse, EF; Eaton, SA; Jane, DE; Jones, PL; Pook, PC; Porter, RH; Roberts, PJ; Sunter, DC; Udvarhelyi, PM; Wharton, B | 1 |
| Casabona, G; Genazzani, AA; L'Episcopo, MR; Nicoletti, F; Shinozaki, H | 1 |
| Jane, DE; Jones, PL; Pook, PC; Salt, TE; Sunter, DC; Watkins, JC | 1 |
| Battaglia, G; Bruno, V; Copani, A; Leanza, G; Nicoletti, F; Pellitteri, R; Russo, A; Stanzani, S | 1 |
| Haruta, H; Hicks, TP; Kamishita, T; Takahashi, MP; Tsumoto, T | 1 |
| Conn, PJ; Winder, DG | 1 |
| Bridges, RJ; Chamberlin, AR; Cotman, CW; Miller, S | 1 |
| Gähwiler, BH; Gerber, U; Lüthi, A | 1 |
| Miller, RF; Thoreson, WB | 1 |
| Littman, L; Robinson, MB | 1 |
| Manzoni, OJ; Nicoll, RA; Weisskopf, MG | 1 |
| Ishida, M; Kwak, S; Miyamoto, M; Shinozaki, H | 1 |
| Collingridge, GL; Henley, JM; Irving, AJ; Seal, AJ | 1 |
| Dichter, MA; Maki, R; Robinson, MB | 1 |
| Cahusac, PM | 1 |
| Hayashi, Y; Higuchi, T; Kaba, H; Nakanishi, S | 1 |
| Baker, SR; Goldsworthy, J; Johnson, BG; Salhoff, CR; Schoepp, DD | 1 |
| Burke, JP; Hablitz, JJ | 2 |
| Hartell, NA | 1 |
| Caciagli, F; Casabona, G; Ciccarelli, R; De Bernardis, E; Di Iorio, P; L'Episcopo, MR; Nicoletti, F; Shinozaki, H | 1 |
| Hölscher, C | 1 |
| Bendali, N; Knöpfel, T; Lingenhöhl, K; Olpe, HR | 1 |
| Bashir, ZI; Bortolotto, ZA; Collingridge, GL; Davies, CH | 1 |
| Jane, D; Jones, A; Jones, P; Kemp, M; Pook, P; Roberts, P; Sunter, D; Udvarhelyi, P; Watkins, J | 1 |
| Ishida, M; Saitoh, T; Shinozaki, H | 1 |
| Eaton, SA; Jane, DE; Jones, PL; Pook, PC; Porter, RH; Roberts, PJ; Salt, TE; Sunter, DC; Udvarhelyi, PM; Watkins, JC | 1 |
| Ishida, M; Ohfune, Y; Saitoh, T; Shimamoto, K; Shinozaki, H | 1 |
| Headley, PM; Jones, MW | 1 |
| Jane, DE; Pittaway, K; Sunter, DC; Thomas, NK; Watkins, JC | 1 |
| Li, A; Nattie, EE | 1 |
| Choi, S; Lovinger, DM | 1 |
| Ohno, M; Watanabe, S | 1 |
| Gilbert, E; Grimwood, S; Hutson, PH; Ragan, CI | 1 |
| Ballerini, P; Battaglia, G; Caciagli, F; Ciccarelli, R; Di Iorio, P; Giuliani, P; Nicoletti, F; Poli, A | 1 |
| Berrino, L; D'Amico, M; de Novellis, V; Pizzirusso, A; Rossi, F | 1 |
| Bruno, V; Marinozzi, M; Nicoletti, F; Pellicciari, R; Thomsen, C | 1 |
| Kamiya, H; Sawada, S; Yamamoto, C; Yoshino, M | 1 |
| Dichter, MA; Fitzsimonds, RM | 1 |
| Bedingfield, JS; Jane, DE; Kemp, MC; Roberts, PJ; Tse, HW; Watkins, JC | 1 |
| Beninger, RJ; Smith, ID | 1 |
| Challiss, RA; Mistry, R | 1 |
| Alexander, SP; Kendall, DA; Neil, KE | 1 |
| Kaneko, A; Sasaki, T | 1 |
| Haruta, H; Hicks, TP; Kamishita, T; Torii, N; Tsumoto, T | 1 |
| Bordi, F; Ugolini, A | 1 |
| Manahan-Vaughan, D; Reymann, KG | 1 |
| D'Angelo, E; rossi, P; Taglietti, V | 1 |
| Consolandi, O; Memo, M; Pizzi, M; Spano, PF | 1 |
| Johnson, BG; Monn, JA; Schoepp, DD | 1 |
| Ohno-Shosaku, T; Yamamoto, C | 1 |
| Bedingfield, JS; Jane, DE; Kemp, MC; Roberts, PJ; Toms, NJ | 1 |
| DiMicco, J; Monroe, AJ | 1 |
| Attwell, D; Sarantis, M; Takahashi, M | 1 |
| el Manira, A; Grillner, S; Krieger, P | 2 |
| Burnett, JP; Desai, MA; Mayne, NG; Schoepp, DD | 1 |
| Bhardwaj, A; Hanley, DF; Koehler, RC; Martin, LJ; Northington, FJ; Traystman, RJ | 1 |
| Belagaje, R; Burnett, JP; Johnson, BG; Mayne, NG; Monn, JA; Salhoff, CR; Schoepp, DD; Wright, RA; Wu, S | 1 |
| King, AE; Liu, XH | 1 |
| Dingledine, R; Doherty, J | 1 |
| Jane, DE; Thomas, NK; Tse, HW; Watkins, JC | 1 |
| Coderre, TJ; Fisher, K | 1 |
| Arai, I; Inoue, H; Shibata, S; Shimazoe, T; Watanabe, S; Yoshimatsu, A | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Pisani, A | 2 |
| Albin, RL; Frey, KA; Kearney, JA | 1 |
| Chapman, AG; Jane, DE; Meldrum, BS; Tang, E; Yip, PK | 1 |
| Colley, PA; Overstreet, LS; Pasternak, JF; Slater, NT; Trommer, BL | 1 |
| Deng, A; Growdon, JH; Nitsch, RM; Wurtman, RJ | 1 |
| Attucci, S; Cozzi, A; Luneia, R; Marinozzi, M; Moroni, F; Pellicciari, R; Peruginelli, F | 1 |
| Komori, Y; Nabeshima, T; Nikai, T; Senzaki, K; Sugihara, H; Yamada, K | 1 |
| de Mendonça, A; Ribeiro, JA | 1 |
| Bordi, F; Corsi, M; Ugolini, A | 2 |
| Neher, E; Schneggenburger, R; von Gersdorff, H; Weis, S | 1 |
| Billard, JM; Dutar, P; Jouvenceau, A | 1 |
| Abbott, A; Lacey, MG; Wigmore, MA | 1 |
| Dumas, TC; Foster, TC | 1 |
| DiJulio, N; Gruol, DL; Parsons, KL | 1 |
| Bear, MF; Huber, KM; Sawtell, NB | 1 |
| Martin, SJ; Morris, RG | 1 |
| Hounsgaard, J; Svirskis, G | 1 |
| Birch, PJ; Blackburn-Munro, G; Bountra, C; Dickinson, T; Fleetwood-Walker, SM; Sparrow, H; Young, MR | 1 |
| Kennedy, RT; Lada, MW; Vickroy, TW | 1 |
| Clayton, P; Jane, DE; Thomas, NK | 1 |
| Beart, PM; Jones, NM; Lawrence, AJ | 1 |
| Amos, BJ; Chesler, M | 1 |
| Maccaferri, G; McBain, CJ; Tóth, K | 1 |
| Camón, L; de Vera, N; Martínez, E; Vives, P | 1 |
| Black, IB; Dreyfus, CF; Elkabes, S; Mount, HT | 1 |
| Anwyl, R; Breakwell, NA; Rowan, MJ | 1 |
| Lacey, MG; Wigmore, MA | 1 |
| Cassidy, EM; O'Connor, JJ; O'Leary, DM | 1 |
| Abraham, WC; Cohen, AS; Raymond, CR | 1 |
| Balázs, R; Chun, Y; Cotman, CW; Miller, S; O'Toole, J | 1 |
| Alford, S; Cochilla, AJ | 1 |
| Wang, JQ | 1 |
| Alger, BE; Kirov, SA; Morishita, W | 1 |
| Salt, TE; Turner, JP | 1 |
| Dickenson, AH; Stanfa, LC | 1 |
| Carfì, M; Cozzi, A; Leonardi, P; Lombardi, G; Moroni, F; Pellicciari, R; Sourtcheva, S | 1 |
| Golshani, P; Jones, EG; Warren, RA | 1 |
| McGee, J; Sanes, DH; Walsh, EJ | 1 |
| Bijak, M; Brański, P; Pałucha, A; Pilc, A; Tokarski, K | 1 |
| Kim, JH; Vezina, P | 1 |
| Conn, PJ; Peavy, RD | 1 |
| Amos, BJ; Mathie, A; Richards, CD | 1 |
| Chu, Z; Hablitz, JJ | 1 |
| Grassi, S; Malfagia, C; Pettorossi, VE | 1 |
| O'Connor, JJ; O'Leary, DM | 1 |
| Chandler, SH; Del Negro, CA | 1 |
| Felipo, V; Llansola, M | 1 |
| Bernardi, G; Spadoni, F; Stefani, A | 1 |
| Pezzola, A; Pintor, A; Tiburzi, F; Volpe, MT | 1 |
| Agrawal, SK; Fehlings, MG; Theriault, E | 1 |
| Bortolotto, ZA; Collingridge, GL; Doherty, AJ; Fitzjohn, SM; Kingston, AE; Lodge, D; Ornstein, PL; Palmer, MJ; Schoepp, DD | 1 |
| Dalby, NO; Thomsen, C | 1 |
| Gee, CE; Lacaille, JC; Robitaille, R; Woodhall, G | 1 |
| Henrich-Noack, P; Reymann, KG | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM | 1 |
| Chamberlain, M; Johnson, MP; Kelly, GM | 1 |
| Bortolotto, ZA; Collingridge, GL | 1 |
| Masgrau, R; Picatoste, F; Sarri, E; Servitja, JM | 1 |
| Berthele, A; Biber, K; Boddeke, HW; Gebicke-Härter, PJ; Laurie, DJ; Sommer, B; Tölle, TR; van Calker, D | 1 |
| Kato, BM; Rubel, EW | 1 |
| Behnisch, T; Manahan-Vaughan, D; Reymann, KG | 1 |
| Foley, CM; Hasser, EM; Hay, M; Mueller, PJ; Vogl, HW | 1 |
| Keele, NB; Neugebauer, V; Shinnick-Gallagher, P | 1 |
| Colwell, CS; Levine, MS | 1 |
| Kalda, A; Zharkovsky, A | 1 |
| Costantino, G; Marinozzi, M; Moroni, F; Natalini, B; Pellegrini-Giampietro, D; Pellicciari, R | 1 |
| Binns, KE; Gasparini, F; Kuhn, R; Salt, TE; Turner, JP | 1 |
| Aggleton, JP; Bashir, ZI; Bortolotto, ZA; Brown, MW; Cho, K; Collingridge, GL; Conquet, F; McCaffery, B | 1 |
| Bernardi, G; Guatteo, E; Knöpfel, T; Mercuri, NB | 1 |
| Hanania, T; Johnson, KM | 1 |
| Mathis, C; Ungerer, A | 1 |
| Auclair, N; Crépel, F; Desce, JM; Otani, S; Roisin, MP | 1 |
| Blanc, EM; Guiramand, J; Jallageas, M; Recasens, M | 1 |
| Herrero, I; Manahan-Vaughan, D; Reymann, KG; Sánchez-Prieto, J | 1 |
| Kaasik, A; Kalda, A; Pokk, P; Vassiljev, V; Zharkovsky, A | 1 |
| Hülsmann, S; Oku, Y; Richter, DW; Zhang, W | 1 |
| Bacon, G; Chen, Y; Clark, BP; Johnson, BG; Kallman, MJ; Kingston, AE; Schoepp, DD; Sher, E; Wright, RA | 1 |
| Nakamura, K; Shirane, M | 1 |
| Benarese, M; Boroni, F; Goffi, F; Pizzi, M; Spano, PF; Valerio, A | 1 |
| Canonico, PL; Copani, A; de Grazia, U; Knöpfel, T; Nicoletti, F; Richelmi, P; Storto, M; Vairetti, M | 1 |
| Crawford, JH; Heavens, R; Martin, DJ; Pollock, J; Scott, RH; Seabrook, GR; Wainwright, A | 1 |
| Dolan, S; Nolan, AM | 1 |
| Albani-Torregrossa, S; Cattabeni, F; Colciaghi, F; De Graan, PN; Di Luca, M; Gardoni, F; Moroni, F; Pastorino, L; Pellegrini-Giampietro, DE | 1 |
| Blatow, M; Giuffrida, R; Monyer, H; van Hooft, JA | 1 |
| Casabona, G; Copani, A; Di Giorgi Gerevini, V; Mutel, V; Nicoletti, F; Nicosia, A; Romano, C; Storto, M | 1 |
| Balcar, VJ; FitzGibbon, T; Lawrance, ML; Pliss, L; Shave, E; Stastny, F | 1 |
| Wiśniewski, K; Zalewska-Wińska, A | 1 |
| Oja, SS; Saransaari, P | 1 |
| Donato, R; Nistri, A | 1 |
| Gerber, G; Kojić, L; Randić, M; Zhong, J | 1 |
| Nagy, F; Voisin, DL | 1 |
| Martin, SJ | 1 |
| Gleason, EL; Kreimborg, KM; Lester, ML; Medler, KF | 1 |
| Haworth, RA; Schomberg, SL; Su, G; Sun, D | 1 |
| Morsette, DJ; Sidorowicz, H; Sladek, CD | 1 |
| Chamberlain, M; Johnson, MP; Kelly, G | 1 |
| Hirose, K; Iino, M; Kakizawa, S; Okubo, Y | 1 |
| Albani-Torregrossa, S; Attucci, S; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Celis, ME; Duvilanski, BH; Lasaga, M; Pampillo, M; Scimonelli, T; Seilicovich, A | 1 |
| Meeker, RB | 1 |
| Johnson, SW; Zheng, F | 2 |
| Boldyrev, AA; Bulygina, ER; Lyapina, LY | 1 |
| Maeda, J; Okauchi, T; Semba, J; Suhara, T | 1 |
| Antunes, VR; Machado, BH | 1 |
| Croucher, MJ; Lee, JJ | 1 |
| Larkum, ME; Lasser-Ross, N; Nakamura, T; Ross, WN; Watanabe, S | 1 |
| Barbanel, G; Kamenka, JM; Laplanche, L; Michaud, M | 1 |
| Alreja, M; Hajszan, T; Leranth, C; Wu, M | 1 |
| Arvanian, VL; Mendell, LM; Motin, V | 1 |
| Andrianov, GN; Demêmes, D; Puyal, J; Raymond, J; Ryzhova, IV; Ventéo, S | 1 |
| Connors, BW; Landisman, CE | 1 |
| Blethyn, KL; Cope, DW; Crunelli, V; Hughes, SW; Tsomaia, V; Zhu, L | 1 |
| Kanumilli, S; Roberts, PJ | 1 |
| Hayashi, K; Ichitani, Y; Yoshihara, T | 1 |
| Dietrich, D; Wostrack, M | 1 |
| Beltramo, M; Brusa, R; Lozza, G; Mancini, I; Petrò, R; Reggiani, A; Scandroglio, P | 1 |
| Charles, JR; Duva, MA; Lara, RL; Ramirez, GJ; Stanley, BG; Yang, CR | 1 |
1 review(s) available for 1-amino-1,3-dicarboxycyclopentane and glycine
| Article | Year |
|---|---|
Ligands for glutamate receptors: design and therapeutic prospects.
Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses | 2000 |
192 other study(ies) available for 1-amino-1,3-dicarboxycyclopentane and glycine
| Article | Year |
|---|---|
3,5-Dihydroxyphenyl-glycine: a potent agonist of metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cycloleucine; Egtazic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Oocytes; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Resorcinols; RNA, Messenger; Xenopus | 1992 |
4C3HPG (RS-4-carboxy-3-hydroxyphenylglycine), a weak agonist at metabotropic glutamate receptors, occludes the action of trans-ACPD in hippocampus.
Topics: Animals; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Ion Channels; Rats; Receptors, Glutamate | 1992 |
Second-messenger responses in brain slices to elucidate novel glutamate receptors.
Topics: Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Guinea Pigs; Hippocampus; Rats; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Resorcinols; Second Messenger Systems | 1995 |
Activation of metabotropic glutamate receptors induces an inward current in rat dopamine mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dopamine; Electrophysiology; Female; Glycine; Male; Neurons; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stimulation, Chemical; Tetrodotoxin | 1993 |
The actions of phenylglycine derived metabotropic glutamate receptor antagonists on multiple (1S,3R)-ACPD responses in the rat nucleus of the tractus solitarius.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Stem; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Membrane Potentials; Muscimol; Neurons; Neurotoxins; Rats; Receptors, GABA-A; Solitary Nucleus; Structure-Activity Relationship; Synaptic Transmission | 1993 |
Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acids, Dicarboxylic; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cycloleucine; Cyclopropanes; Glycine; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Phosphatidylinositols; Receptors, Metabotropic Glutamate | 1994 |
Competitive antagonism by phenylglycine derivatives at type I metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Benzoates; Binding, Competitive; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cycloleucine; Cytidine Diphosphate Diglycerides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; Neurons; Neurotoxins; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Signal Transduction | 1994 |
The function of metabotropic excitatory amino acid receptors in synaptic transmission in the thalamus: studies with novel phenylglycine antagonists.
Topics: Action Potentials; Air; Animals; Benzoates; Cycloleucine; Glycine; Hot Temperature; Iontophoresis; Neurons; Nociceptors; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Thalamus | 1994 |
Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebral Cortex; Cycloleucine; Glycine; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Phosphatidylinositols; Rats; Receptors, Glutamate; Spinal Cord; Thalamus | 1993 |
(2s,1'R,2'R,3'R)-2-(2,3-Dicarboxycyclopropyl) glycine enhances quisqualate-stimulated inositol phospholipid hydrolysis in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1993 |
Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Ibotenic Acid; Motor Neurons; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Rats; Spinal Cord; Stereoisomerism; Thalamus | 1993 |
Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide.
Topics: Aminobutyrates; Amyloid beta-Peptides; Animals; Apoptosis; Benzoates; Calcium Channels; Cells, Cultured; Cerebellum; Cycloleucine; Glycine; Mice; Nerve Degeneration; Neurons; Peptide Fragments; Phosphoserine; Receptors, Metabotropic Glutamate | 1995 |
Induction of LTD but not LTP through metabotropic glutamate receptors in visual cortex.
Topics: Animals; Benzoates; Calcium; Cycloleucine; Depression, Chemical; Glycine; In Vitro Techniques; Long-Term Potentiation; Neuronal Plasticity; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Visual Cortex | 1994 |
Metabotropic glutamate receptor (mGluR)-mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR.
Topics: Animals; Brain; Calcium; Calcium-Transporting ATPases; Cyclic AMP; Cycloleucine; Glycine; Hydrolysis; In Vitro Techniques; Intracellular Membranes; Neurotoxins; Phosphatidylinositols; Protein Kinase C; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Terpenes; Thapsigargin | 1995 |
Pharmacological dissociation of glutamatergic metabotropic signal transduction pathways in cortical astrocytes.
Topics: Animals; Astrocytes; Benzoates; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cycloleucine; Dicarboxylic Acids; Glutamic Acid; Glycine; Isoproterenol; Neuroglia; Neurotoxins; Phosphatidylinositols; Pyrrolidines; Rats; Receptors, Metabotropic Glutamate; Signal Transduction | 1994 |
Inhibition of a slow synaptic response by a metabotropic glutamate receptor antagonist in hippocampal CA3 pyramidal cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Bicuculline; Cycloleucine; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Nerve Fibers; Neurotoxins; Pyramidal Cells; Quinoxalines; Rats; Receptors, Glutamate; Synapses | 1993 |
Actions of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) in retinal ON bipolar cells indicate that it is an agonist at L-AP4 receptors.
Topics: Aminobutyrates; Animals; Cycloleucine; Excitatory Amino Acid Agonists; GABA-A Receptor Agonists; Glycine; Necturus maculosus; Receptors, GABA-A; Receptors, Glutamate; Retina | 1994 |
The effects of L-glutamate and trans-(+-)-1-amino-1,3-cyclopentanedicarboxylate on phosphoinositide hydrolysis can be pharmacologically differentiated.
Topics: Alanine; Animals; Animals, Newborn; Aspartic Acid; Benzoates; Brain; Cerebellum; Cycloleucine; Glutamic Acid; Glycine; Hippocampus; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kinetics; Neurotoxins; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Stereoisomerism | 1994 |
MCPG antagonizes metabotropic glutamate receptors but not long-term potentiation in the hippocampus.
Topics: Animals; Benzoates; Cycloleucine; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Neurotoxins; Receptors, Metabotropic Glutamate; Stereoisomerism; Synapses; Synaptic Transmission | 1994 |
Agonists for metabotropic glutamate receptors in the rat delay recovery from halothane anesthesia.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Anesthesia; Animals; Cycloleucine; Cyclopropanes; Glycine; Halothane; Injections, Intraventricular; Male; Neurotoxins; Postural Balance; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1994 |
Stereoselective antagonism of the metabotropic glutamate receptor mGluR1 alpha by alpha-methyl-4-carboxyphenylglycine.
Topics: Animals; Benzoates; Calcium; CHO Cells; Cricetinae; Cycloleucine; Glycine; Perfusion; Receptors, Metabotropic Glutamate; Stereoisomerism | 1994 |
The glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate depresses excitatory synaptic transmission via a presynaptic mechanism in cultured hippocampal neurons.
Topics: Animals; Benzoates; Cells, Cultured; Cycloleucine; Dicarboxylic Acids; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Neurons; Presynaptic Terminals; Pyrrolidines; Rats; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Synaptic Transmission | 1994 |
Cortical layer-specific effects of the metabotropic glutamate receptor agonist 1S,3R-ACPD in rat primary somatosensory cortex in vivo.
Topics: Aminobutyrates; Animals; Benzoates; Cycloleucine; Glycine; Iontophoresis; Male; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Somatosensory Cortex; Synapses | 1994 |
Induction of an olfactory memory by the activation of a metabotropic glutamate receptor.
Topics: Animals; Cycloleucine; Cyclopropanes; Estrus; Female; gamma-Aminobutyric Acid; Glycine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Neuronal Plasticity; Olfactory Bulb; Phentolamine; Pheromones; Pregnancy; Pregnancy, Animal; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Sexual Behavior, Animal | 1994 |
3,5-dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus.
Topics: Aging; Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Colforsin; Cyclic AMP; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Kinetics; Male; Neurotoxins; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Resorcinols; Second Messenger Systems | 1994 |
Presynaptic depression of synaptic transmission mediated by activation of metabotropic glutamate receptors in rat neocortex.
Topics: Aminobutyrates; Animals; Benzoates; Cycloleucine; Electrophysiology; Female; Frontal Lobe; Glycine; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Presynaptic; Synaptic Transmission | 1994 |
Induction of cerebellar long-term depression requires activation of glutamate metabotropic receptors.
Topics: Aniline Compounds; Animals; Benzoates; Biotransformation; Cerebellum; Cyclic GMP; Cycloleucine; Cyclopropanes; Evoked Potentials; Fluorescent Dyes; Glycine; In Vitro Techniques; Nerve Fibers; Neuronal Plasticity; Neurotoxins; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Xanthenes | 1994 |
Interaction between metabotropic receptors and purinergic transmission in rat hippocampal slices.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; In Vitro Techniques; Male; Neurotoxins; Purines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1994 |
Inhibitors of metabotropic glutamate receptors produce amnestic effects in chicks.
Topics: Aminobutyrates; Amnesia; Animals; Avoidance Learning; Benzoates; Chickens; Cycloleucine; Cyclopropanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Male; Motor Activity; Phosphoserine; Receptors, Metabotropic Glutamate | 1994 |
Phenylglycine derivatives antagonize the excitatory response to Purkinje cells to 1S,3R-ACPD: an in vivo and in vitro study.
Topics: Action Potentials; Animals; Benzoates; Cerebellum; Cycloleucine; Electrophysiology; Glycine; In Vitro Techniques; Iontophoresis; Male; Neurotoxins; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1993 |
A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation.
Topics: Animals; Benzoates; Carbazoles; Cycloleucine; Glycine; Hippocampus; In Vitro Techniques; Indole Alkaloids; Long-Term Potentiation; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 1994 |
Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors.
Topics: Aminobutyrates; Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Electrophysiology; Glycine; Guinea Pigs; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1994 |
A new metabotropic glutamate receptor agonist: developmental change of its sensitivity to receptors in the newborn rat spinal cord.
Topics: Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Baclofen; Cycloleucine; Cyclopropanes; Dose-Response Relationship, Drug; Glycine; In Vitro Techniques; Neurotoxins; Rats; Rats, Wistar; Receptors, Glutamate; Spinal Cord; Synapses | 1993 |
Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine.
Topics: Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Chromatography, High Pressure Liquid; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Phosphatidylinositols; Rats; Spinal Cord; Synapses; Thalamus | 1993 |
A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord.
Topics: Amino Acids; Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Cycloleucine; Cyclopropanes; Electric Stimulation; Electrophysiology; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurotoxins; Rats; Rats, Wistar; Receptors, Glutamate; Reflex, Monosynaptic; Spinal Cord | 1993 |
Interactions between metabotropic and ionotropic glutamate receptor agonists in the rat spinal cord in vivo.
Topics: Action Potentials; Animals; Blood Pressure; Cycloleucine; Electrophoresis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 1995 |
New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord.
Topics: Aminobutyrates; Animals; Animals, Newborn; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Motor Neurons; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Spinal Cord; Tetrodotoxin | 1995 |
Prolonged stimulation of respiration by brain stem metabotropic glutamate receptors.
Topics: Analysis of Variance; Animals; Benzoates; Brain Stem; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Microinjections; Microscopy, Fluorescence; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Respiration; Stimulation, Chemical | 1995 |
Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons.
Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Cycloleucine; Cyclopropanes; Electrophysiology; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Ion Channel Gating; Neurons; Neurotoxins; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spider Venoms | 1996 |
Persistent increase in dopamine release following activation of metabotropic glutamate receptors in the rat nucleus accumbens.
Topics: Animals; Benzoates; Chromatography, High Pressure Liquid; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Male; Microdialysis; N-Methylaspartate; Neurotoxins; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1995 |
Modulation of 45Ca2+ influx into cells stably expressing recombinant human NMDA receptors by ligands acting at distinct recognition sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Calcium Radioisotopes; Cycloleucine; Dithionitrobenzoic Acid; Dithiothreitol; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Humans; Kainic Acid; L Cells; Ligands; Mice; Neurotoxins; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spermine; Sulfhydryl Reagents | 1996 |
Interaction between A1 adenosine and class II metabotropic glutamate receptors in the regulation of purine and glutamate release from rat hippocampal slices.
Topics: Adenosine; Animals; Cycloleucine; Cyclopropanes; Excitatory Amino Acids; Glutamic Acid; Glycine; Hippocampus; Male; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Xanthines | 1996 |
Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzoates; Blood Pressure; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Male; Microinjections; N-Methylaspartate; Neurotoxins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Valine | 1996 |
(2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a potent and selective antagonist of type 2 metabotropic glutamate receptors.
Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Cerebral Cortex; Cricetinae; Cyclic AMP; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Glycine; Kidney; Kinetics; Mice; N-Methylaspartate; Neuroglia; Neurons; Neurotoxins; Phosphatidylinositols; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 1996 |
A metabotropic glutamate receptor agonist DCG-IV suppresses synaptic transmission at mossy fiber pathway of the guinea pig hippocampus.
Topics: Aminobutyrates; Animals; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Receptors, Metabotropic Glutamate | 1996 |
Heterologous modulation of inhibitory synaptic transmission by metabotropic glutamate receptors in cultured hippocampal neurons.
Topics: Animals; Benzoates; Cells, Cultured; Cycloleucine; Dicarboxylic Acids; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Neural Inhibition; Neurons; Neurotransmitter Uptake Inhibitors; Patch-Clamp Techniques; Pyrrolidines; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1996 |
Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs).
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Glycine; Inositol Phosphates; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 1995 |
Contralateral turning caused by metabotropic glutamate receptor stimulation in the dorsal striatum is reversed by MCPG, TTX, and cis-flupenthixol.
Topics: Animals; Benzoates; Corpus Striatum; Cycloleucine; Dominance, Cerebral; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Glycine; Male; Motor Activity; Neurons; Neurotoxins; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stereotyped Behavior; Synaptic Transmission; Tetrodotoxin | 1996 |
Differences in agonist and antagonist activities for two indices of metabotropic glutamate receptor-stimulated phosphoinositide turnover.
Topics: Animals; Benzoates; Cerebral Cortex; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glycine; Inositol 1,4,5-Trisphosphate; Male; Molecular Conformation; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1996 |
Coupling of metabotropic glutamate receptors to phosphoinositide mobilisation and inhibition of cyclic AMP generation in the guinea-pig cerebellum.
Topics: 2-Chloroadenosine; Animals; Cerebellum; Colforsin; Cyclic AMP; Cycloleucine; Female; Glutamic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Phosphatidylinositols; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
L-Glutamate-induced responses in OFF-type bipolar cells of the cat retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Calcium; Cats; Chlorides; Cycloleucine; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; In Vitro Techniques; Ion Transport; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium; Retina; Retinal Cone Photoreceptor Cells; Sodium | 1996 |
Metabotropic glutamate receptors and visual cortical synaptic plasticity.
Topics: Animals; Benzoates; Calcium; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Long-Term Potentiation; Male; Neuronal Plasticity; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Visual Cortex | 1995 |
Metabotropic glutamate group II receptors are responsible for the depression of synaptic transmission induced by ACPD in the dentate gyrus.
Topics: Animals; Benzoates; Cycloleucine; Dentate Gyrus; Excitatory Amino Acid Antagonists; Glycine; Male; Rats; Rats, Wistar; Receptors, Glutamate; Synaptic Transmission | 1995 |
1S,3R-ACPD dose dependently induces a slow onset potentiation in the dentate gyrus in vivo.
Topics: Action Potentials; Animals; Benzoates; Cycloleucine; Dentate Gyrus; Dose-Response Relationship, Drug; Glycine; Long-Term Potentiation; Male; Rats; Rats, Wistar; Synaptic Transmission | 1995 |
Differential long-lasting potentiation of the NMDA and non-NMDA synaptic currents induced by metabotropic and NMDA receptor coactivation in cerebellar granule cells.
Topics: Animals; Benzoates; Cerebellum; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Potentiation; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1996 |
Activation of multiple metabotropic glutamate receptor subtypes prevents NMDA-induced excitotoxicity in rat hippocampal slices.
Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neuroprotective Agents; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1996 |
(1 S,3 R)-1-aminocyclopentane-1,3-dicarboxylic acid-induced increases in cyclic AMP formation in the neonatal rat hippocampus are mediated by a synergistic interaction between phosphoinositide- and inhibitory cyclic AMP-coupled mGluRs.
Topics: Animals; Animals, Newborn; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
Effects of metabotropic glutamate receptor agonists on excitatory and inhibitory transmissions in cultured rat hippocampal neurons.
Topics: Animals; Animals, Newborn; Benzoates; Cells, Cultured; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Neural Inhibition; Neurons; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Synaptic Transmission | 1995 |
Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors.
Topics: Animals; Cells, Cultured; Cerebellum; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Glycine; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1996 |
G-protein activation by metabotropic glutamate receptors reduces spike frequency adaptation in neocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides | 1996 |
Stimulation of metabotropic glutamate receptors in the dorsomedial hypothalamus elevates heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cycloleucine; Dose-Response Relationship, Drug; Glycine; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Tachycardia | 1996 |
Postsynaptic glutamate uptake in rat cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ion Channel Gating; Kynurenic Acid; Membrane Potentials; Monosaccharide Transport Proteins; Neuroprotective Agents; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin | 1996 |
Activation of pharmacologically distinct metabotropic glutamate receptors depresses reticulospinal-evoked monosynaptic EPSPs in the lamprey spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Axons; Benzoates; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Lampreys; Neural Pathways; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Reticular Formation; Spinal Cord; Synaptic Transmission | 1996 |
Pharmacological characterization of desensitization in a human mGlu1 alpha-expressing non-neuronal cell line co-transfected with a glutamate transporter.
Topics: Amino Acid Transport System X-AG; Animals; Carrier Proteins; Cell Line; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Glycoproteins; Humans; Hydrolysis; Inosine Triphosphate; Inositol; Neurotoxins; Phosphatidylinositols; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
Characterization of metabotropic glutamate receptor-mediated nitric oxide production in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Biomarkers; Calcium Channels; Citrulline; Cycloleucine; Dantrolene; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Male; Microdialysis; Muscle Proteins; N-Methylaspartate; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Ryanodine Receptor Calcium Release Channel; Tetrodotoxin | 1997 |
The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors.
Topics: Aging; Animals; Animals, Newborn; Brain; Cloning, Molecular; Colforsin; Cyclic AMP; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Humans; Inositol; Kinetics; Neuroprotective Agents; Phosphatidylinositols; Proline; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Second Messenger Systems | 1996 |
Dual action of metabotropic glutamate receptor agonists on neuronal excitability and synaptic transmission in spinal ventral horn neurons in vitro.
Topics: Amino Acids, Dicarboxylic; Animals; Anterior Horn Cells; Benzoates; Cycloleucine; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Rats; Spinal Cord; Synaptic Transmission; Time Factors | 1996 |
Regulation of excitatory input to inhibitory interneurons of the dentate gyrus during hypoxia.
Topics: Animals; Benzoates; Cycloleucine; Dentate Gyrus; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hypoxia, Brain; In Vitro Techniques; Interneurons; Kinetics; Male; Membrane Potentials; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Synaptic Transmission | 1997 |
Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Animals, Newborn; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamates; Glycine; N-Methylaspartate; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Spinal Cord | 1996 |
The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception.
Topics: Aminobutyrates; Analysis of Variance; Animals; Benzoates; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Male; Pain; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
Methamphetamine-induced sensitization of dopamine release via a metabotropic glutamate receptor mediated pathway in rat striatal slices.
Topics: Analysis of Variance; Animals; Benzoates; Corpus Striatum; Cycloleucine; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraperitoneal; Male; Methamphetamine; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stereoisomerism | 1997 |
Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones.
Topics: Animals; Cycloleucine; Excitatory Amino Acid Agents; Glycine; Male; N-Methylaspartate; Neostriatum; Neurons; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 1997 |
Metabotropic glutamate agonist-induced rotation: a pharmacological, FOS immunohistochemical, and [14C]-2-deoxyglucose autoradiographic study.
Topics: Animals; Autoradiography; Basal Ganglia; Behavior, Animal; Caffeine; Carbon Radioisotopes; Cycloleucine; Deoxyglucose; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Glucose; Glycine; Immunohistochemistry; Male; Neuroprotective Agents; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Receptors, Purinergic P1; Resorcinols; Rotation; Salicylamides; Thalamic Nuclei; Xanthines | 1997 |
Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats.
Topics: Animals; Behavior, Animal; Cycloleucine; Dose-Response Relationship, Drug; Epilepsy; Female; Glycine; Inferior Colliculi; Male; Neuroprotective Agents; Noise; Phosphoserine; Rats; Receptors, Metabotropic Glutamate | 1997 |
Metabotropic glutamate receptor mediated long-term depression in developing hippocampus.
Topics: Animals; Benzoates; Cycloleucine; Depression, Chemical; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Neuroprotective Agents; Nitrendipine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Theophylline | 1997 |
Activation of group III metabotropic glutamate receptors depresses glutamatergic transmission at corticostriatal synapse.
Topics: Aminobutyrates; Animals; Benzoates; Corpus Striatum; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Neural Inhibition; Neuroprotective Agents; Phosphoserine; Presynaptic Terminals; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1997 |
Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain.
Topics: Amyloid beta-Protein Precursor; Benzoates; Cell Line; Cycloleucine; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Glycine; GTP-Binding Proteins; Humans; Melitten; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Protein Kinases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Transfection; Type C Phospholipases | 1997 |
Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: in vivo studies with (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a new potent and selective antagonist.
Topics: Animals; Benzoates; Caudate Nucleus; Corpus Striatum; Cyclic AMP; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1997 |
Changes in extracellular nitrite and nitrate levels after inhibition of glial metabolism with fluorocitrate.
Topics: Aconitate Hydratase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzoates; Cerebellum; Citrates; Citric Acid Cycle; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; Male; N-Methylaspartate; Neuroglia; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Quinoxalines; Rats; Rats, Wistar; Substrate Specificity | 1997 |
Influence of metabotropic glutamate receptor agonists on the inhibitory effects of adenosine A1 receptor activation in the rat hippocampus.
Topics: Adenosine; Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Resorcinols | 1997 |
Potentiation of NMDA and AMPA responses by group I mGluR in spinal cord motoneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; Motor Neurons; N-Methylaspartate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 1997 |
Presynaptic depression at a calyx synapse: the small contribution of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Afferent Pathways; Aminobutyrates; Animals; Brain Stem; Cycloleucine; Electric Stimulation; Glutamic Acid; Glycine; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1997 |
Is activation of the metabotropic glutamate receptors impaired in the hippocampal CA1 area of the aged rat?
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1997 |
Excitation of rat subthalamic nucleus neurones in vitro by activation of a group I metabotropic glutamate receptor.
Topics: Adenine Nucleotides; Affinity Labels; Animals; Benzoates; Cycloleucine; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Male; Neurons; Neuroprotective Agents; Pyridoxal; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Thalamic Nuclei | 1997 |
Development of metabotropic glutamate receptor-mediated synaptic inhibition.
Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1997 |
Acute ethanol alters calcium signals elicited by glutamate receptor agonists and K+ depolarization in cultured cerebellar Purkinje neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebellar Cortex; Cycloleucine; Embryo, Mammalian; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Membrane Potentials; Potassium; Purkinje Cells; Rats; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Resorcinols | 1997 |
Effects of the metabotropic glutamate receptor antagonist MCPG on phosphoinositide turnover and synaptic plasticity in visual cortex.
Topics: Action Potentials; Age Factors; Animals; Benzoates; Binding, Competitive; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Long-Term Potentiation; Neuronal Plasticity; Neuroprotective Agents; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Metabotropic Glutamate; Synapses; Visual Cortex | 1998 |
(R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) fails to block long-term potentiation under urethane anaesthesia in vivo.
Topics: Analysis of Variance; Anesthesia; Anesthetics, Intravenous; Animals; Benzoates; Body Temperature; Brain; Cycloleucine; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Male; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Tetanus; Time Factors; Urethane | 1997 |
Transmitter regulation of plateau properties in turtle motoneurons.
Topics: Animals; Atropine; Baclofen; Benzoates; Calcium Channels; Calcium Channels, L-Type; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; Muscarine; Nifedipine; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Tetraethylammonium; Tetrodotoxin; Turtles | 1998 |
Behavioural and electrophysiological evidence supporting a role for group I metabotropic glutamate receptors in the mediation of nociceptive inputs to the rat spinal cord.
Topics: Alanine; Animals; Antihypertensive Agents; Behavior, Animal; Benzothiadiazines; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Glycine; Male; Mustard Plant; Neuroprotective Agents; Nociceptors; Pain; Phenylacetates; Plant Extracts; Plant Oils; Plants, Medicinal; Rats; Rats, Inbred Strains; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 1997 |
Evidence for neuronal origin and metabotropic receptor-mediated regulation of extracellular glutamate and aspartate in rat striatum in vivo following electrical stimulation of the prefrontal cortex.
Topics: Animals; Aspartic Acid; Benzoates; Calcium; Corpus Striatum; Cycloleucine; Dicarboxylic Acids; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycine; Male; Neurons; Neurotransmitter Uptake Inhibitors; Prefrontal Cortex; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tetrodotoxin; Time Factors | 1998 |
Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Kinetics; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Rats; Spinal Cord | 1997 |
In vivo microdialysis reveals facilitatory metabotropic glutamate receptors regulating excitatory amino acid release in rat nucleus tractus solitarius.
Topics: Animals; Aspartic Acid; Benzoates; Calcium; Chromatography, High Pressure Liquid; Cycloleucine; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Glycine; Kinetics; Male; Microdialysis; Neurotoxins; Rats; Rats, Inbred WKY; Receptors, Metabotropic Glutamate; Solitary Nucleus; Tetrodotoxin | 1998 |
Characterization of an intracellular alkaline shift in rat astrocytes triggered by metabotropic glutamate receptors.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Chloro-7-nitrobenzofurazan; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Animals, Newborn; Anti-Bacterial Agents; Astrocytes; Benzoates; Caffeine; Calcium; Cells, Cultured; Chlorides; Cycloleucine; Dicyclohexylcarbodiimide; Enzyme Inhibitors; Glycine; HEPES; Hydrogen-Ion Concentration; Indans; Intracellular Fluid; Ion Transport; Ionomycin; Ionophores; Macrolides; Nigericin; Rats; Receptors, Metabotropic Glutamate; Sodium | 1998 |
Target-specific expression of presynaptic mossy fiber plasticity.
Topics: Afferent Pathways; Animals; Colforsin; Cyclic AMP; Cycloleucine; Cyclopropanes; Electric Stimulation; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Long-Term Potentiation; Mossy Fibers, Hippocampal; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1998 |
Seizures and neuronal damage induced in the rat by activation of group I metabotropic glutamate receptors with their selective agonist 3,5-dihydroxyphenylglycine.
Topics: Analysis of Variance; Animals; Cerebral Ventricles; Cycloleucine; Excitatory Amino Acid Agonists; Glycine; Infusions, Parenteral; Male; Motor Activity; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Seizures | 1998 |
Differential involvement of metabotropic and p75 neurotrophin receptors in effects of nerve growth factor and neurotrophin-3 on cultured Purkinje cell survival.
Topics: Animals; Cell Survival; Cycloleucine; Enzyme Inhibitors; Glycine; Nerve Growth Factors; Neuroprotective Agents; Neurotrophin 3; Protein Kinase C; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor; Receptors, Metabotropic Glutamate; Receptors, Nerve Growth Factor; Signal Transduction | 1998 |
(+)-MCPG blocks induction of LTP in CA1 of rat hippocampus via agonist action at an mGluR group II receptor.
Topics: Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neuroprotective Agents; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1998 |
Metabotropic glutamate receptors depress glutamate-mediated synaptic input to rat midbrain dopamine neurones in vitro.
Topics: Alanine; Animals; Benzoates; Cycloleucine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamates; Glycine; In Vitro Techniques; Male; Mesencephalon; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1998 |
Group II and III metabotropic glutamate receptors modulate paired pulse depression in the rat dentate gyrus in vitro.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Cycloleucine; Cyclopropanes; Dentate Gyrus; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 1997 |
Priming of long-term potentiation induced by activation of metabotropic glutamate receptors coupled to phospholipase C.
Topics: Animals; Cycloleucine; Electric Stimulation; Estrenes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neuroprotective Agents; Pyramidal Cells; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Type C Phospholipases | 1998 |
Metabotropic glutamate receptor agonists potentiate cyclic AMP formation induced by forskolin or beta-adrenergic receptor activation in cerebral cortical astrocytes in culture.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Cycloleucine; Drug Synergism; Estrenes; Excitatory Amino Acid Agonists; Glycine; Neocortex; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Adrenergic, beta; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Type C Phospholipases; Up-Regulation | 1998 |
Metabotropic glutamate receptor-mediated control of neurotransmitter release.
Topics: 4-Aminopyridine; Animals; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Lampreys; Membrane Potentials; Motor Neurons; Neuroprotective Agents; Neurotransmitter Agents; Potassium; Presynaptic Terminals; Receptors, Metabotropic Glutamate; Resorcinols; Ryanodine; Spinal Cord; Synaptic Transmission | 1998 |
Regulation of immediate early gene c-fos and zif/268 mRNA expression in rat striatum by metabotropic glutamate receptor.
Topics: Animals; Benzazepines; Benzoates; Corpus Striatum; Cycloleucine; DNA-Binding Proteins; Dopamine Antagonists; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Excitatory Amino Acid Antagonists; Gene Expression; Genes, Immediate-Early; Glycine; Immediate-Early Proteins; In Situ Hybridization; Male; Microinjections; Neuroprotective Agents; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Metabotropic Glutamate; RNA, Messenger; Transcription Factors; Zinc Fingers | 1998 |
Evidence for metabotropic glutamate receptor activation in the induction of depolarization-induced suppression of inhibition in hippocampal CA1.
Topics: 4-Aminopyridine; Amino Acids, Dicarboxylic; Animals; Benzoates; Calcium Channels; Cycloleucine; Cyclopropanes; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Male; Membrane Potentials; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Signal Transduction; Synapses | 1998 |
Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4-carboxy-phenylglycine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; N-Methylaspartate; Naphthols; Neurons, Afferent; Neuroprotective Agents; Propylene Glycols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus | 1998 |
Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones.
Topics: Animals; Carrageenan; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Inflammation; Male; Neurons; Pain; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Supine Position | 1998 |
Presynaptic mGlu1 type receptors potentiate transmitter output in the rat cortex.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indans; Microdialysis; Parietal Lobe; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Resorcinols | 1998 |
Progression of change in NMDA, non-NMDA, and metabotropic glutamate receptor function at the developing corticothalamic synapse.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Mice; Mice, Inbred ICR; Nerve Fibers; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Thalamus | 1998 |
Metabotropic glutamate receptor activation modulates sound level processing in the cochlear nucleus.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Auditory Perception; Benzoates; Cats; Cochlear Nucleus; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; N-Methylaspartate; Neurons; Neuroprotective Agents; Receptors, Metabotropic Glutamate; Time Factors | 1998 |
Antidepressant treatment influences group I of glutamate metabotropic receptors in slices from hippocampal CA1 region.
Topics: Action Potentials; Animals; Antidepressive Agents, Tricyclic; Cycloleucine; Electroshock; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Imipramine; Inositol Phosphates; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 1998 |
The metabotropic glutamate receptor antagonist (RS)-MCPG produces hyperlocomotion in amphetamine pre-exposed rats.
Topics: Amphetamine; Animals; Benzoates; Central Nervous System Stimulants; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraventricular; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1998 |
Phosphorylation of mitogen-activated protein kinase in cultured rat cortical glia by stimulation of metabotropic glutamate receptors.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Glycine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Neuroglia; Neuroprotective Agents; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Tyrosine | 1998 |
Activation of group I metabotropic glutamate receptors elicits pH changes in cultured rat cortical glia and neurons.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Chelating Agents; Cycloleucine; Egtazic Acid; Enzyme Inhibitors; Glycine; Hydrogen-Ion Concentration; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1998 |
Activation of group I mGluRs increases spontaneous IPSC frequency in rat frontal cortex.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Frontal Lobe; Glycine; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Tetrodotoxin | 1998 |
Effects of metabotropic glutamate receptor block on the synaptic transmission and plasticity in the rat medial vestibular nuclei.
Topics: Animals; Benzoates; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Potentiation; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Vestibular Nuclei | 1998 |
Priming of long-term potentiation by prior activation of group I and II metabotropic glutamate receptors in the rat dentate gyrus in vitro.
Topics: Amino Acids, Dicarboxylic; Animals; Cycloleucine; Dentate Gyrus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Long-Term Potentiation; Membrane Potentials; Neuroprotective Agents; Phenylacetates; Propionates; Rats; Receptors, Metabotropic Glutamate | 1998 |
Regulation of intrinsic and synaptic properties of neonatal rat trigeminal motoneurons by metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Trigeminal Nuclei | 1998 |
Carnitine inhibits hydrolysis of inositol phospholipids induced by activation of metabotropic receptors.
Topics: Animals; Carbachol; Carnitine; Catechols; Cycloleucine; Glycine; GTP-Binding Proteins; Hippocampus; Hydrolysis; Male; Neuroprotective Agents; Norepinephrine; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Type C Phospholipases | 1998 |
Endogenous activation of metabotropic glutamate receptors contributes to burst frequency regulation in the lamprey locomotor network.
Topics: Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Lampreys; Locomotion; Membrane Potentials; N-Methylaspartate; Nerve Net; Periodicity; Propionates; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Synaptic Transmission | 1998 |
Group I mGluRs modulate calcium currents in rat GP: functional implications.
Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cycloleucine; Electric Conductivity; Excitatory Amino Acid Antagonists; Globus Pallidus; Glycine; Male; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 1998 |
Metabotropic glutamate receptor agonist (1S,3R-ACPD) increased frontal cortex dopamine release in aged but not in young rats.
Topics: Animals; Benzoates; Cycloleucine; Dopamine; Excitatory Amino Acid Antagonists; Frontal Lobe; Glycine; Male; Microdialysis; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Time Factors | 1998 |
Role of group I metabotropic glutamate receptors in traumatic spinal cord white matter injury.
Topics: Age Factors; Animals; Astrocytes; Benzoates; Cycloleucine; Electrophysiology; Estrenes; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glycine; Immunohistochemistry; Male; Membrane Potentials; Nerve Fibers; Neuroprotective Agents; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Spinal Cord Injuries; Type C Phospholipases | 1998 |
The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity.
Topics: Aging; Amino Acids; Animals; Binding, Competitive; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Neuronal Plasticity; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Transfection; Xanthenes | 1998 |
Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetrazole-induced seizure activity in mice.
Topics: Animals; Cerebral Ventricles; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Indans; Infusions, Parenteral; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Reaction Time; Resorcinols; Seizures | 1998 |
Membrane potential and intracellular Ca2+ oscillations activated by mGluRs in hippocampal stratum oriens/alveus interneurons.
Topics: Animals; Benzoates; Calcium; Calcium Signaling; Cycloleucine; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Image Processing, Computer-Assisted; In Vitro Techniques; Interneurons; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tetrodotoxin | 1999 |
(1S,3R)-ACPD, a metabotropic glutamate receptor agonist, enhances damage after global ischaemia.
Topics: Animals; Benzoates; Brain Ischemia; Cell Count; Cell Survival; Cycloleucine; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; Hippocampus; Male; Neurons; Neuroprotective Agents; Receptors, Metabotropic Glutamate | 1999 |
Mechanisms involved in the metabotropic glutamate receptor-enhancement of NMDA-mediated motoneurone responses in frog spinal cord.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chlorpromazine; Cycloleucine; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; GTP-Binding Proteins; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Pertussis Toxin; Rana pipiens; Receptors, Metabotropic Glutamate; Reflex; Resorcinols; Second Messenger Systems; Spinal Cord; Sulfonamides; Tetrodotoxin; Thapsigargin; Virulence Factors, Bordetella | 1999 |
Phosphoinositide hydrolysis in vivo with group I metabotropic glutamate receptor agonists.
Topics: Amino Acids; Animals; Brain Chemistry; Cerebellum; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Hydrolysis; Injections, Intraventricular; Male; Neuroprotective Agents; Phenylacetates; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Tritium; Type C Phospholipases; Xanthenes | 1999 |
Evidence that a novel metabotropic glutamate receptor mediates the induction of long-term potentiation at CA1 synapses in the hippocampus.
Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Synapses | 1999 |
Group I metabotropic glutamate receptors mediate phospholipase D stimulation in rat cultured astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Benzoates; Carcinogens; Cerebellum; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Neurons; Neuroprotective Agents; Norepinephrine; Phospholipase D; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sympathomimetics; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1999 |
Expression and signaling of group I metabotropic glutamate receptors in astrocytes and microglia.
Topics: Animals; Astrocytes; Benzoates; Brain; Brain Chemistry; Calcium; Cells, Cultured; Cycloleucine; DNA Primers; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Glycine; In Situ Hybridization; Inositol 1,4,5-Trisphosphate; Microglia; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 1999 |
Glutamate regulates IP3-type and CICR stores in the avian cochlear nucleus.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alanine; Animals; Benzoates; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Chelating Agents; Chick Embryo; Cochlear Nucleus; Cyclic AMP; Cycloleucine; Cysteine; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Gallic Acid; Glutamic Acid; Glycine; Ibotenic Acid; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Receptors, Cytoplasmic and Nuclear; Ryanodine; Second Messenger Systems; Thionucleotides | 1999 |
ACPD-mediated slow-onset potentiation is associated with cell death in the rat CA1 region in vivo.
Topics: Animals; Benzoates; Cell Death; Cell Survival; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Neuronal Plasticity; Neuroprotective Agents; Rats; Rats, Wistar | 1999 |
Cardiovascular response to group I metabotropic glutamate receptor activation in NTS.
Topics: Animals; Baroreflex; Benzoates; Blood Pressure; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Kynurenic Acid; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sympathetic Nervous System | 1999 |
Differential effects of metabotropic glutamate receptor antagonists on bursting activity in the amygdala.
Topics: Amygdala; Animals; Benzoates; Cycloleucine; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kindling, Neurologic; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses | 1999 |
Metabotropic glutamate receptor modulation of excitotoxicity in the neostriatum: role of calcium channels.
Topics: Animals; Barium; Brain Edema; Cadmium; Calcium Channel Blockers; Calcium Channels; Cycloleucine; Excitatory Amino Acid Agonists; Glycine; Membrane Potentials; Methoxyhydroxyphenylglycol; Microscopy, Video; N-Methylaspartate; Neostriatum; Neuroprotective Agents; Neurotoxins; omega-Conotoxin GVIA; Organ Culture Techniques; Patch-Clamp Techniques; Peptides; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1999 |
Metabotropic glutamate receptor agonists protect from oxygen-glucose deprivation- and colchicine-induced apoptosis in primary cultures of cerebellar granule cells.
Topics: Animals; Apoptosis; Cell Hypoxia; Cells, Cultured; Cerebellum; Colchicine; Cycloleucine; Cyclopropanes; Glucose; Glycine; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1999 |
(2R,1'S,2'R,3'S)-2-(2'-Carboxy-3'-phenylcyclopropyl)glycine (PCCG-13), the first potent and selective competitive antagonist of phospholipase D-coupled metabotropic glutamate receptors: asymmetric synthesis and preliminary biological properties.
Topics: Animals; Cycloleucine; Cyclopropanes; Glycerophospholipids; Glycine; Hippocampus; In Vitro Techniques; Phospholipase D; Rats; Receptors, Metabotropic Glutamate; Stereoisomerism; Type C Phospholipases | 1999 |
Antagonism of the mGlu5 agonist 2-chloro-5-hydroxyphenylglycine by the novel selective mGlu5 antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) in the thalamus.
Topics: Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Phenylacetates; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus | 1999 |
Synaptic depression induced by pharmacological activation of metabotropic glutamate receptors in the perirhinal cortex in vitro.
Topics: Animals; Cycloleucine; Cyclopropanes; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; Neocortex; Neuronal Plasticity; Organ Culture Techniques; Propionates; Rats; Rats, Inbred Strains; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Temporal Lobe | 1999 |
Group I metabotropic glutamate receptors mediate an inward current in rat substantia nigra dopamine neurons that is independent from calcium mobilization.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Chromones; Cycloleucine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Microscopy, Fluorescence; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Substantia Nigra; Tetrodotoxin; Thapsigargin | 1999 |
Potentiation of NMDA and AMPA responses by the specific mGluR5 agonist CHPG in spinal cord motoneurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzophenanthridines; Calcium; Cycloleucine; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Phenanthridines; Phenylacetates; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Spinal Cord | 1999 |
Regulation of NMDA-stimulated [14C]GABA and [3H]acetylcholine release by striatal glutamate and dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Carbon Radioisotopes; Corpus Striatum; Cycloleucine; Dopamine Agonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Male; N-Methylaspartate; Proline; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
The retention deficit induced by (RS)-alpha-methyl-4-carboxyphenylglycine in a lever-press learning task is blocked by selective agonists of either group I or group II metabotropic glutamate receptors.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cycloleucine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Learning; Male; Memory Disorders; Mice; Mice, Inbred Strains; Neuroprotective Agents; Protein Isoforms; Receptors, Metabotropic Glutamate; Resorcinols; Retention, Psychology; Time Factors | 1999 |
Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases.
Topics: Animals; Benzoates; Cycloleucine; Dopamine; Electric Stimulation; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Indans; Kinetics; Male; Mitogen-Activated Protein Kinases; Models, Neurological; Neuronal Plasticity; Phosphoserine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate | 1999 |
Potentiation of glutamatergic agonist-induced inositol phosphate formation by basic fibroblast growth factor is related to developmental features in hippocampal cultures: neuronal survival and glial cell proliferation.
Topics: Animals; Antimetabolites, Antineoplastic; Benzoates; Cell Division; Cell Survival; Cells, Cultured; Cellular Senescence; Cycloleucine; Cytarabine; Epidermal Growth Factor; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Fibroblast Growth Factor 2; Glutamic Acid; Glycine; Hippocampus; Inositol Phosphates; Neuroglia; Neurons; Neuroprotective Agents; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Type C Phospholipases | 1999 |
Presynaptic group 1 metabotropic glutamate receptors may contribute to the expression of long-term potentiation in the hippocampal CA1 region.
Topics: Animals; Azetidinecarboxylic Acid; Calcium; Cycloleucine; Dicarboxylic Acids; Diglycerides; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; Long-Term Potentiation; Male; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Presynaptic Terminals; Pyrrolidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptosomes | 1999 |
Neuroprotective action of group I metabotropic glutamate receptor agonists against oxygen-glucose deprivation-induced neuronal death.
Topics: Animals; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebellum; Cycloleucine; Electrophoresis, Agar Gel; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glucose; Glycine; In Situ Nick-End Labeling; Indans; Indoles; Maleimides; Neurons; Neuroprotective Agents; Protein Kinase C; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 2000 |
Metabotropic glutamate receptors and blockade of glial Krebs cycle depress glycinergic synaptic currents of mouse hypoglossal motoneurons.
Topics: Animals; Animals, Newborn; Aspartic Acid; Citric Acid Cycle; Cycloleucine; Cyclopropanes; Excitatory Postsynaptic Potentials; Female; Glycine; Hypoglossal Nerve; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred Strains; Motor Neurons; Neuroglia; Neuroprotective Agents; Patch-Clamp Techniques; Propionates; Receptors, Metabotropic Glutamate; Synapses | 2000 |
Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl)propionic acid) in the in vitro neonatal spinal cord and in an in vivo pain model.
Topics: Acetic Acid; Animals; Animals, Newborn; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Mice; Motor Neurons; Neuroprotective Agents; Nociceptors; Pain; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Spinal Nerve Roots; Stereoisomerism | 2000 |
Group II metabotropic glutamate receptors are a common target of N-anisoyl-GABA and 1S,3R-ACPD in enhancing ACh release in the prefrontal cortex of freely moving SHRSP.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Anisoles; Benzoates; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Indans; Male; Microdialysis; Perfusion; Prefrontal Cortex; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, AMPA; Receptors, Metabotropic Glutamate; Thalamic Nuclei; Wakefulness | 2000 |
Neuroprotection by metabotropic glutamate receptor agonists on kainate-induced degeneration of motor neurons in spinal cord slices from adult rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Cell Survival; Choline O-Acetyltransferase; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Situ Nick-End Labeling; In Vitro Techniques; Kainic Acid; Male; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord | 2000 |
Selective blockade of mGlu5 metabotropic glutamate receptors protects rat hepatocytes against hypoxic damage.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Hypoxia; Cells, Cultured; Cycloleucine; Excitatory Amino Acid Agonists; Glycine; Immunohistochemistry; Liver; Male; Neuroprotective Agents; Pyridines; Quisqualic Acid; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2000 |
Mobilisation of intracellular Ca2+ by mGluR5 metabotropic glutamate receptor activation in neonatal rat cultured dorsal root ganglia neurones.
Topics: Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Cells, Cultured; Cycloleucine; Cyclopropanes; Dantrolene; Fluorescence; Ganglia, Spinal; Glutamic Acid; Glycine; Indans; Phenylacetates; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; Stereoisomerism | 2000 |
Behavioural evidence supporting a differential role for group I and II metabotropic glutamate receptors in spinal nociceptive transmission.
Topics: Amino Acids, Dicarboxylic; Animals; Behavior, Animal; Chronic Disease; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Indans; Injections, Spinal; Nociceptors; Pain Threshold; Physical Stimulation; Receptors, Metabotropic Glutamate; Resorcinols; Sheep; Spinal Cord; Synaptic Transmission | 2000 |
(+)-MCPG induces PKCepsilon translocation in cortical synaptosomes through a PLD-coupled mGluR.
Topics: Animals; Benzoates; Cerebral Cortex; Chelating Agents; Cycloleucine; Cyclopropanes; Egtazic Acid; Enzyme Activation; Excitatory Amino Acid Antagonists; Glycine; Isoenzymes; Male; Neurons; Neuroprotective Agents; Phospholipase D; Presynaptic Terminals; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptosomes | 2000 |
Differential expression of group I metabotropic glutamate receptors in functionally distinct hippocampal interneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression; Glycine; Hippocampus; Interneurons; Neuroprotective Agents; Patch-Clamp Techniques; Periodicity; Picrotoxin; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Tetrodotoxin | 2000 |
Reducing conditions differentially affect the functional and structural properties of group-I and -II metabotropic glutamate receptors.
Topics: Amino Acids, Dicarboxylic; Animals; Anticonvulsants; Carbachol; Cell Membrane; Cerebellum; CHO Cells; Cholinergic Agonists; Colforsin; Cricetinae; Cyclic AMP; Cycloleucine; Cyclopropanes; Dimerization; Dithiothreitol; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Humans; Kidney; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Signal Transduction | 2000 |
Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Brain Chemistry; Carboxypeptidases; Cold Temperature; Cycloleucine; Cyclopropanes; Dipeptides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamate Carboxypeptidase II; Glycine; Kainic Acid; Male; Nerve Tissue Proteins; Phosphoserine; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tetrazoles | 2001 |
Behavioural activity of (S)-3,5-DHPG, a selective agonist of group I metabotropic glutamate receptors.
Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Cycloleucine; Exploratory Behavior; Glycine; Long-Term Potentiation; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 2000 |
Involvement of metabotropic glutamate receptors in ischemia-induced taurine release in the developing and adult hippocampus.
Topics: Aging; Animals; Brain Ischemia; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamates; Glycine; Hippocampus; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred Strains; Neurons; Receptors, Metabotropic Glutamate; Taurine | 2000 |
Relative contribution by GABA or glycine to Cl(-)-mediated synaptic transmission on rat hypoglossal motoneurons in vitro.
Topics: Animals; Chlorides; Cycloleucine; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Hypoglossal Nerve; In Vitro Techniques; Motor Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Glycine; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin | 2000 |
Dual modulation of excitatory synaptic transmission by agonists at group I metabotropic glutamate receptors in the rat spinal dorsal horn.
Topics: Animals; Benzoates; Bicuculline; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glycine; In Vitro Techniques; Kinetics; Magnesium; Male; Methoxyhydroxyphenylglycol; Nerve Fibers; Phenylacetates; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord; Strychnine; Substantia Gelatinosa; Synaptic Transmission | 2000 |
Sustained L-type calcium currents in dissociated deep dorsal horn neurons of the rat: characteristics and modulation.
Topics: Animals; Baclofen; Barium; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 2001 |
Activation of metabotropic glutamate receptors induces gamma frequency oscillations in the rat dentate gyrus in vivo.
Topics: Animals; Benzoates; Cycloleucine; Dentate Gyrus; Electroencephalography; Excitatory Amino Acid Antagonists; Glycine; Male; Rats; Receptors, Metabotropic Glutamate; Time Factors | 2001 |
Group I metabotropic glutamate receptors are expressed in the chicken retina and by cultured retinal amacrine cells.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Blotting, Western; Calcium Signaling; Cells, Cultured; Chickens; Cycloleucine; Excitatory Amino Acid Agonists; Eye Proteins; Fluorescent Antibody Technique, Indirect; gamma-Aminobutyric Acid; Glycine; Molecular Sequence Data; Molecular Weight; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Retina | 2001 |
Stimulation of Na-K-2Cl cotransporter in neurons by activation of Non-NMDA ionotropic receptor and group-I mGluRs.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Carrier Proteins; Cells, Cultured; Chromones; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fetus; Glycine; Neurons; Neuroprotective Agents; Phosphorylation; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters | 2001 |
Role of metabotropic glutamate receptors in vasopressin and oxytocin release.
Topics: Aminobutyrates; Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hypothalamo-Hypophyseal System; In Vitro Techniques; Indans; Male; Neurons; Neuroprotective Agents; Osmolar Concentration; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Vasopressins | 2001 |
Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Amino Acids; Animals; Benzoates; Bridged Bicyclo Compounds; Corticosterone; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Phenylacetates; Propionates; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Xanthenes | 2001 |
Visualization of IP(3) dynamics reveals a novel AMPA receptor-triggered IP(3) production pathway mediated by voltage-dependent Ca(2+) influx in Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Blood Proteins; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cycloleucine; Cytoplasm; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Vectors; Glutamic Acid; Glycine; Green Fluorescent Proteins; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred ICR; Neuroprotective Agents; Patch-Clamp Techniques; Phosphoproteins; Purkinje Cells; Receptors, AMPA; Receptors, Metabotropic Glutamate; Sindbis Virus | 2001 |
Metabotropic glutamate receptors stimulate phospholipase D via different pathways in the adult and neonate rat hippocampus.
Topics: Aging; Animals; Animals, Newborn; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; Kinetics; Methoxyhydroxyphenylglycol; Phospholipase D; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 2001 |
The activation of metabotropic glutamate receptors differentially affects GABA and alpha-melanocyte stimulating hormone release from the hypothalamus and the posterior pituitary of male rats.
Topics: alpha-MSH; Animals; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Hypothalamus; Indans; Male; Neuroprotective Agents; Pituitary Gland, Posterior; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 2002 |
Metabotropic and NMDA glutamate receptor interactions with osmotic stimuli in supraoptic neurons.
Topics: Animals; Calcium Signaling; Cells, Cultured; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Female; Glycine; Image Processing, Computer-Assisted; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Neurosecretory Systems; Osmolar Concentration; Pregnancy; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus | 2002 |
Group I metabotropic glutamate receptor-mediated enhancement of dopamine cell burst firing in rat ventral tegmental area in vitro.
Topics: Action Potentials; Animals; Apamin; Benzoates; Biological Clocks; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Ventral Tegmental Area | 2002 |
Activation of glutamate receptors inhibits Na/K-ATPase of cerebellum granule cells.
Topics: Alkaloids; Animals; Benzoates; Benzophenanthridines; Cerebellum; Cycloleucine; Cysteine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Glycine; Male; Mice; Mice, Inbred AKR; N-Methylaspartate; Neurons; Phenanthridines; Receptors, Glutamate; Sodium-Potassium-Exchanging ATPase | 2002 |
Different roles of group I and group II metabotropic glutamate receptors on phencyclidine-induced dopamine release in the rat prefrontal cortex.
Topics: Animals; Anticonvulsants; Cycloleucine; Cyclopropanes; Dopamine; Dopamine Agents; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; Hallucinogens; Male; Microdialysis; Neuroprotective Agents; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Time Factors | 2003 |
Antagonism of glutamatergic metabotropic receptors in the NTS of awake rats does not affect the gain of the baroreflex.
Topics: Animals; Baroreflex; Benzoates; Blood Pressure; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Heart Rate; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Solitary Nucleus | 2003 |
Actions of Group I and Group II metabotropic glutamate receptor ligands on 5-hydroxytryptamine release in the rat cerebral cortex in vivo: differential roles in the regulation of central serotonergic neurotransmission.
Topics: Amino Acids, Dicarboxylic; Analysis of Variance; Anesthetics, Local; Animals; Benzoates; Calcium; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Ligands; Male; Microdialysis; Potassium Chloride; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Serotonin; Synaptic Transmission; Tetrodotoxin | 2003 |
Synaptically activated Ca2+ waves in layer 2/3 and layer 5 rat neocortical pyramidal neurons.
Topics: Action Potentials; Animals; Calcium; Carbachol; Cholinergic Agonists; Cycloleucine; Dendrites; Glycine; Heparin; In Vitro Techniques; Intracellular Membranes; Neocortex; Osmolar Concentration; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Ryanodine; Synapses; Tissue Distribution | 2003 |
Dual modulation of gabaergic transmission by metabotropic glutamate receptors in rat ventral tegmental area.
Topics: Anesthetics, Local; Animals; Bicuculline; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrophysiology; Enkephalins; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Leucine; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Neural Conduction; Neural Inhibition; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Ventral Tegmental Area | 2003 |
Hydroxyl radicals release in rat striatum involves metabotropic glutamate receptors.
Topics: Analysis of Variance; Animals; Corpus Striatum; Cycloleucine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxyl Radical; Male; Methoxyhydroxyphenylglycol; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Time Factors | 2003 |
Nicotine recruits a local glutamatergic circuit to excite septohippocampal GABAergic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Acyclovir; Animals; Animals, Newborn; Atropine; Bicuculline; Bungarotoxins; Carrier Proteins; Cell Count; Choline; Chromones; Cycloleucine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electric Conductivity; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Membrane Transport Proteins; Microscopy, Electron; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parvalbumins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Resorcinols; Septum of Brain; Synapses; Tetrodotoxin; Tubocurarine; Valine; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins | 2003 |
Comparison of metabotropic glutamate receptor responses at segmental and descending inputs to motoneurons in neonatal rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Benzoates; Brain-Derived Neurotrophic Factor; Cycloleucine; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Motor Neurons; Neurotrophin 3; Patch-Clamp Techniques; Phosphinic Acids; Rats; Receptors, Metabotropic Glutamate; Spinal Cord; Spinal Nerve Roots | 2005 |
Immunocytochemical and pharmacological characterization of metabotropic glutamate receptors of the vestibular end organs in the frog.
Topics: Animals; Blotting, Western; Brain; Cycloleucine; Electrophysiology; Glutamic Acid; Glycine; Hair Cells, Auditory; Immunohistochemistry; Neurons, Afferent; Neuroprotective Agents; Neurotransmitter Agents; Rana temporaria; Rats; Receptors, Metabotropic Glutamate; Semicircular Canals; Vestibular Nerve | 2005 |
Long-term modulation of electrical synapses in the mammalian thalamus.
Topics: Action Potentials; Animals; Cycloleucine; Electric Conductivity; Electric Stimulation; Excitatory Postsynaptic Potentials; Gap Junctions; Glycine; In Vitro Techniques; Intralaminar Thalamic Nuclei; Membrane Potentials; Neocortex; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synapses | 2005 |
Nucleus- and species-specific properties of the slow (<1 Hz) sleep oscillation in thalamocortical neurons.
Topics: Action Potentials; Animals; Benzoates; Cats; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons; Periodicity; Rats; Rats, Wistar; Sleep Stages; Species Specificity; Thalamic Nuclei | 2006 |
Mechanisms of glutamate receptor induced proliferation of astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Count; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Cycloleucine; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycerophospholipids; Glycine; Indoles; Maleimides; Methoxyhydroxyphenylglycol; Phospholipase D; Pyridines; Rats; Rats, Wistar; Receptors, Glutamate; Tritium | 2006 |
Involvement of hippocampal metabotropic glutamate receptors in radial maze performance.
Topics: Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Injections, Intraventricular; Male; Maze Learning; Memory; Microinjections; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Spatial Behavior | 2007 |
Involvement of Group II mGluRs in mossy fiber LTD.
Topics: Amino Acids; Amino Acids, Dicarboxylic; Animals; Cycloleucine; Cyclopropanes; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Neural Inhibition; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission; Xanthenes | 2009 |
Evaluation of cannabinoid receptor 2 and metabotropic glutamate receptor 1 functional responses using a cell impedance-based technology.
Topics: Analgesics; Animals; Benzimidazoles; Biological Assay; Calcium; Cannabinoids; CHO Cells; Chromones; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanols; Cycloleucine; Electric Impedance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indoles; Naphthalenes; Neuroprotective Agents; Quinolines; Quisqualic Acid; Receptor, Cannabinoid, CB2; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Thiazoles | 2010 |
Activation of lateral hypothalamic mGlu1 and mGlu5 receptors elicits feeding in rats.
Topics: Animals; Benzimidazoles; Benzopyrans; Cycloleucine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hypothalamus; Male; Phenylacetates; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Thiazoles; Time Factors | 2014 |