Compounds > 1-amino-1,3-dicarboxycyclopentane

1-amino-1,3-dicarboxycyclopentane and alpha-methyl-4-carboxyphenylglycine

1-amino-1,3-dicarboxycyclopentane has been researched along with alpha-methyl-4-carboxyphenylglycine in 103 studies

Research

Studies (103)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	85 (82.52)	18.2507
2000's	18 (17.48)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Costantino, G; Pellicciari, R	1
Costantino, G; Marinozzi, M; Moroni, F; Natalini, B; Pellegrini-Giampietro, D; Pellicciari, R	1
Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Adam, G; Cartmell, J; Chaboz, S; Henningsen, R; Kemp, JA; Klingelschmidt, A; Metzler, V; Monsma, F; Mutel, V; Schaffhauser, H; Wichmann, J	1
Arnold, MB; Johnson, BG; Ornstein, PL; Schoepp, DD; Wheeler, WJ; Wright, RA	1
Adam, G; Bleuel, Z; Chaboz, S; Ellis, GJ; Faull, RL; Malherbe, P; Messer, J; Metzler, V; Mutel, V; Nilly, A; Richards, JG; Roughley, BS; Schlaeger, EJ	1
Arnold, MB; Ornstein, PL; Schoepp, DD; Wheeler, WJ; Wright, RA	1
Bischoff, F; Janssen, C; Langlois, X; Lavreysen, H; Lesage, AS; Leysen, JE	1
Cavanni, P; Eistetter, H; Ferraguti, F; Ratti, E; Salvagno, C; Trist, DG	1
Eaton, SA; Salt, TE	1
Jane, DE; Jones, PL; Pook, PC; Salt, TE; Sunter, DC; Watkins, JC	1
Battaglia, G; Bruno, V; Copani, A; Leanza, G; Nicoletti, F; Pellitteri, R; Russo, A; Stanzani, S	1
Haruta, H; Hicks, TP; Kamishita, T; Takahashi, MP; Tsumoto, T	1
Bridges, RJ; Chamberlin, AR; Cotman, CW; Miller, S	1
Gähwiler, BH; Gerber, U; Lüthi, A	1
Littman, L; Robinson, MB	1
Manzoni, OJ; Nicoll, RA; Weisskopf, MG	1
Collingridge, GL; Henley, JM; Irving, AJ; Seal, AJ	1
Dichter, MA; Maki, R; Robinson, MB	1
Cahusac, PM	1
Burke, JP; Hablitz, JJ	2
Hartell, NA	1
Hölscher, C	1
Bendali, N; Knöpfel, T; Lingenhöhl, K; Olpe, HR	1
Bashir, ZI; Bortolotto, ZA; Collingridge, GL; Davies, CH	1
Jane, D; Jones, A; Jones, P; Kemp, M; Pook, P; Roberts, P; Sunter, D; Udvarhelyi, P; Watkins, J	1
Eaton, SA; Jane, DE; Jones, PL; Pook, PC; Porter, RH; Roberts, PJ; Salt, TE; Sunter, DC; Udvarhelyi, PM; Watkins, JC	1
Li, A; Nattie, EE	1
Choi, S; Lovinger, DM	1
Ohno, M; Watanabe, S	1
Berrino, L; D'Amico, M; de Novellis, V; Pizzirusso, A; Rossi, F	1
Dichter, MA; Fitzsimonds, RM	1
Beninger, RJ; Smith, ID	1
Challiss, RA; Mistry, R	1
Haruta, H; Hicks, TP; Kamishita, T; Torii, N; Tsumoto, T	1
Bordi, F; Ugolini, A	1
Manahan-Vaughan, D; Reymann, KG	1
D'Angelo, E; rossi, P; Taglietti, V	1
Consolandi, O; Memo, M; Pizzi, M; Spano, PF	1
Ohno-Shosaku, T; Yamamoto, C	1
Attwell, D; Sarantis, M; Takahashi, M	1
el Manira, A; Grillner, S; Krieger, P	1
Bhardwaj, A; Hanley, DF; Koehler, RC; Martin, LJ; Northington, FJ; Traystman, RJ	1
King, AE; Liu, XH	1
Dingledine, R; Doherty, J	1
Coderre, TJ; Fisher, K	1
Arai, I; Inoue, H; Shibata, S; Shimazoe, T; Watanabe, S; Yoshimatsu, A	1
Colley, PA; Overstreet, LS; Pasternak, JF; Slater, NT; Trommer, BL	1
Bernardi, G; Calabresi, P; Centonze, D; Pisani, A	1
Deng, A; Growdon, JH; Nitsch, RM; Wurtman, RJ	1
Attucci, S; Cozzi, A; Luneia, R; Marinozzi, M; Moroni, F; Pellicciari, R; Peruginelli, F	1
Komori, Y; Nabeshima, T; Nikai, T; Senzaki, K; Sugihara, H; Yamada, K	1
Billard, JM; Dutar, P; Jouvenceau, A	1
Abbott, A; Lacey, MG; Wigmore, MA	1
Dumas, TC; Foster, TC	1
Bear, MF; Huber, KM; Sawtell, NB	1
Martin, SJ; Morris, RG	1
Hounsgaard, J; Svirskis, G	1
Kennedy, RT; Lada, MW; Vickroy, TW	1
Beart, PM; Jones, NM; Lawrence, AJ	1
Amos, BJ; Chesler, M	1
Anwyl, R; Breakwell, NA; Rowan, MJ	1
Lacey, MG; Wigmore, MA	1
Cassidy, EM; O'Connor, JJ; O'Leary, DM	1
Wang, JQ	1
Alger, BE; Kirov, SA; Morishita, W	1
Salt, TE; Turner, JP	1
Golshani, P; Jones, EG; Warren, RA	1
McGee, J; Sanes, DH; Walsh, EJ	1
Kim, JH; Vezina, P	1
Grassi, S; Malfagia, C; Pettorossi, VE	1
Chandler, SH; Del Negro, CA	1
Bernardi, G; Spadoni, F; Stefani, A	1
Pezzola, A; Pintor, A; Tiburzi, F; Volpe, MT	1
Agrawal, SK; Fehlings, MG; Theriault, E	1
Gee, CE; Lacaille, JC; Robitaille, R; Woodhall, G	1
Davidoff, RA; Hackman, JC; Holohean, AM	1
Bortolotto, ZA; Collingridge, GL	1
Masgrau, R; Picatoste, F; Sarri, E; Servitja, JM	1
Berthele, A; Biber, K; Boddeke, HW; Gebicke-Härter, PJ; Laurie, DJ; Sommer, B; Tölle, TR; van Calker, D	1
Kato, BM; Rubel, EW	1
Behnisch, T; Manahan-Vaughan, D; Reymann, KG	1
Foley, CM; Hasser, EM; Hay, M; Mueller, PJ; Vogl, HW	1
Keele, NB; Neugebauer, V; Shinnick-Gallagher, P	1
Hanania, T; Johnson, KM	1
Mathis, C; Ungerer, A	1
Auclair, N; Crépel, F; Desce, JM; Otani, S; Roisin, MP	1
Blanc, EM; Guiramand, J; Jallageas, M; Recasens, M	1
Nakamura, K; Shirane, M	1
Benarese, M; Boroni, F; Goffi, F; Pizzi, M; Spano, PF; Valerio, A	1
Albani-Torregrossa, S; Cattabeni, F; Colciaghi, F; De Graan, PN; Di Luca, M; Gardoni, F; Moroni, F; Pastorino, L; Pellegrini-Giampietro, DE	1
Blatow, M; Giuffrida, R; Monyer, H; van Hooft, JA	1
Martin, SJ	1
Chamberlain, M; Johnson, MP; Kelly, G	1
Hirose, K; Iino, M; Kakizawa, S; Okubo, Y	1
Johnson, SW; Zheng, F	1
Boldyrev, AA; Bulygina, ER; Lyapina, LY	1
Antunes, VR; Machado, BH	1
Croucher, MJ; Lee, JJ	1
Arvanian, VL; Mendell, LM; Motin, V	1
Blethyn, KL; Cope, DW; Crunelli, V; Hughes, SW; Tsomaia, V; Zhu, L	1

Reviews

1 review(s) available for 1-amino-1,3-dicarboxycyclopentane and alpha-methyl-4-carboxyphenylglycine

Article	Year
Ligands for glutamate receptors: design and therapeutic prospects. Journal of medicinal chemistry, 2000, Jul-13, Volume: 43, Issue:14 Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses	2000

Other Studies

102 other study(ies) available for 1-amino-1,3-dicarboxycyclopentane and alpha-methyl-4-carboxyphenylglycine

Article	Year
Homology modeling of metabotropic glutamate receptors. (mGluRs) structural motifs affecting binding modes and pharmacological profile of mGluR1 agonists and competitive antagonists. Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20 Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Computer Simulation; Electrochemistry; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Conformation; Protein Structure, Secondary; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Sequence Homology	1996
(2R,1'S,2'R,3'S)-2-(2'-Carboxy-3'-phenylcyclopropyl)glycine (PCCG-13), the first potent and selective competitive antagonist of phospholipase D-coupled metabotropic glutamate receptors: asymmetric synthesis and preliminary biological properties. Journal of medicinal chemistry, 1999, Jul-15, Volume: 42, Issue:14 Topics: Animals; Cycloleucine; Cyclopropanes; Glycerophospholipids; Glycine; Hippocampus; In Vitro Techniques; Phospholipase D; Rats; Receptors, Metabotropic Glutamate; Stereoisomerism; Type C Phospholipases	1999
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes. British journal of pharmacology, 1998, Volume: 123, Issue:3 Topics: Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclopropanes; Glycine; Guanosine 5'-O-(3-Thiotriphosphate); Protein Binding; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Sulfur Radioisotopes; Transfection; Tritium	1998
[3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells. Neuropharmacology, 1999, Volume: 38, Issue:10 Topics: Amino Acids; Animals; Binding, Competitive; Calcium; Cell Membrane; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Kinetics; Radioligand Assay; Receptors, Metabotropic Glutamate; Recombinant Proteins; Transfection; Tritium; Xanthenes	1999
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections. Journal of neurochemistry, 2000, Volume: 75, Issue:6 Topics: Animals; Binding, Competitive; Brain; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Imidazoles; Indans; Intracellular Fluid; Kainic Acid; Male; Organ Specificity; Quinazolines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spinal Cord; Transfection	2000
Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl) glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:6 Topics: Amino Acids; Binding, Competitive; Cell Membrane; Excitatory Amino Acid Antagonists; Humans; Kinetics; Radioligand Assay; Receptors, Metabotropic Glutamate; Recombinant Proteins; Substrate Specificity; Tritium; Xanthenes	2000
[3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists. Molecular pharmacology, 2003, Volume: 63, Issue:5 Topics: Adamantane; Allosteric Regulation; Animals; Binding Sites; Binding, Competitive; Brain; Cell Line; Cell Membrane; CHO Cells; Chromones; Cricetinae; Humans; Naphthalenes; Pyrans; Quinolines; Quinoxalines; Quisqualic Acid; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Transfection; Tritium	2003
Competitive antagonism by phenylglycine derivatives at type I metabotropic glutamate receptors. Molecular and cellular neurosciences, 1994, Volume: 5, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Benzoates; Binding, Competitive; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cycloleucine; Cytidine Diphosphate Diglycerides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; Neurons; Neurotoxins; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Signal Transduction	1994
The function of metabotropic excitatory amino acid receptors in synaptic transmission in the thalamus: studies with novel phenylglycine antagonists. Neurochemistry international, 1994, Volume: 24, Issue:5 Topics: Action Potentials; Air; Animals; Benzoates; Cycloleucine; Glycine; Hot Temperature; Iontophoresis; Neurons; Nociceptors; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Thalamus	1994
Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones. Neuropharmacology, 1993, Volume: 32, Issue:7 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Ibotenic Acid; Motor Neurons; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Rats; Spinal Cord; Stereoisomerism; Thalamus	1993
Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide. Molecular pharmacology, 1995, Volume: 47, Issue:5 Topics: Aminobutyrates; Amyloid beta-Peptides; Animals; Apoptosis; Benzoates; Calcium Channels; Cells, Cultured; Cerebellum; Cycloleucine; Glycine; Mice; Nerve Degeneration; Neurons; Peptide Fragments; Phosphoserine; Receptors, Metabotropic Glutamate	1995
Induction of LTD but not LTP through metabotropic glutamate receptors in visual cortex. Neuroreport, 1994, Sep-08, Volume: 5, Issue:14 Topics: Animals; Benzoates; Calcium; Cycloleucine; Depression, Chemical; Glycine; In Vitro Techniques; Long-Term Potentiation; Neuronal Plasticity; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Visual Cortex	1994
Pharmacological dissociation of glutamatergic metabotropic signal transduction pathways in cortical astrocytes. European journal of pharmacology, 1994, Oct-14, Volume: 269, Issue:2 Topics: Animals; Astrocytes; Benzoates; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cycloleucine; Dicarboxylic Acids; Glutamic Acid; Glycine; Isoproterenol; Neuroglia; Neurotoxins; Phosphatidylinositols; Pyrrolidines; Rats; Receptors, Metabotropic Glutamate; Signal Transduction	1994
Inhibition of a slow synaptic response by a metabotropic glutamate receptor antagonist in hippocampal CA3 pyramidal cells. Proceedings. Biological sciences, 1993, Nov-22, Volume: 254, Issue:1340 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Bicuculline; Cycloleucine; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Nerve Fibers; Neurotoxins; Pyramidal Cells; Quinoxalines; Rats; Receptors, Glutamate; Synapses	1993
The effects of L-glutamate and trans-(+-)-1-amino-1,3-cyclopentanedicarboxylate on phosphoinositide hydrolysis can be pharmacologically differentiated. Journal of neurochemistry, 1994, Volume: 63, Issue:4 Topics: Alanine; Animals; Animals, Newborn; Aspartic Acid; Benzoates; Brain; Cerebellum; Cycloleucine; Glutamic Acid; Glycine; Hippocampus; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kinetics; Neurotoxins; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Stereoisomerism	1994
MCPG antagonizes metabotropic glutamate receptors but not long-term potentiation in the hippocampus. The European journal of neuroscience, 1994, Jun-01, Volume: 6, Issue:6 Topics: Animals; Benzoates; Cycloleucine; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Neurotoxins; Receptors, Metabotropic Glutamate; Stereoisomerism; Synapses; Synaptic Transmission	1994
Stereoselective antagonism of the metabotropic glutamate receptor mGluR1 alpha by alpha-methyl-4-carboxyphenylglycine. Biochemical Society transactions, 1994, Volume: 22, Issue:2 Topics: Animals; Benzoates; Calcium; CHO Cells; Cricetinae; Cycloleucine; Glycine; Perfusion; Receptors, Metabotropic Glutamate; Stereoisomerism	1994
The glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate depresses excitatory synaptic transmission via a presynaptic mechanism in cultured hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:11 Pt 1 Topics: Animals; Benzoates; Cells, Cultured; Cycloleucine; Dicarboxylic Acids; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Neurons; Presynaptic Terminals; Pyrrolidines; Rats; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Synaptic Transmission	1994
Cortical layer-specific effects of the metabotropic glutamate receptor agonist 1S,3R-ACPD in rat primary somatosensory cortex in vivo. The European journal of neuroscience, 1994, Sep-01, Volume: 6, Issue:9 Topics: Aminobutyrates; Animals; Benzoates; Cycloleucine; Glycine; Iontophoresis; Male; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Somatosensory Cortex; Synapses	1994
Presynaptic depression of synaptic transmission mediated by activation of metabotropic glutamate receptors in rat neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:8 Topics: Aminobutyrates; Animals; Benzoates; Cycloleucine; Electrophysiology; Female; Frontal Lobe; Glycine; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Presynaptic; Synaptic Transmission	1994
Induction of cerebellar long-term depression requires activation of glutamate metabotropic receptors. Neuroreport, 1994, Apr-14, Volume: 5, Issue:8 Topics: Aniline Compounds; Animals; Benzoates; Biotransformation; Cerebellum; Cyclic GMP; Cycloleucine; Cyclopropanes; Evoked Potentials; Fluorescent Dyes; Glycine; In Vitro Techniques; Nerve Fibers; Neuronal Plasticity; Neurotoxins; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Xanthenes	1994
Inhibitors of metabotropic glutamate receptors produce amnestic effects in chicks. Neuroreport, 1994, May-09, Volume: 5, Issue:9 Topics: Aminobutyrates; Amnesia; Animals; Avoidance Learning; Benzoates; Chickens; Cycloleucine; Cyclopropanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Male; Motor Activity; Phosphoserine; Receptors, Metabotropic Glutamate	1994
Phenylglycine derivatives antagonize the excitatory response to Purkinje cells to 1S,3R-ACPD: an in vivo and in vitro study. Neuroscience research, 1993, Volume: 18, Issue:3 Topics: Action Potentials; Animals; Benzoates; Cerebellum; Cycloleucine; Electrophysiology; Glycine; In Vitro Techniques; Iontophoresis; Male; Neurotoxins; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate	1993
A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation. Nature, 1994, Apr-21, Volume: 368, Issue:6473 Topics: Animals; Benzoates; Carbazoles; Cycloleucine; Glycine; Hippocampus; In Vitro Techniques; Indole Alkaloids; Long-Term Potentiation; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction	1994
Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors. European journal of pharmacology, 1994, Jan-15, Volume: 266, Issue:2 Topics: Aminobutyrates; Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Electrophysiology; Glycine; Guinea Pigs; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission	1994
Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine. European journal of pharmacology, 1993, Jan-15, Volume: 244, Issue:2 Topics: Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Chromatography, High Pressure Liquid; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Phosphatidylinositols; Rats; Spinal Cord; Synapses; Thalamus	1993
Prolonged stimulation of respiration by brain stem metabotropic glutamate receptors. Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 79, Issue:5 Topics: Analysis of Variance; Animals; Benzoates; Brain Stem; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Microinjections; Microscopy, Fluorescence; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Respiration; Stimulation, Chemical	1995
Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Volume: 16, Issue:1 Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Cycloleucine; Cyclopropanes; Electrophysiology; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Ion Channel Gating; Neurons; Neurotoxins; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spider Venoms	1996
Persistent increase in dopamine release following activation of metabotropic glutamate receptors in the rat nucleus accumbens. Neuroscience letters, 1995, Nov-17, Volume: 200, Issue:2 Topics: Animals; Benzoates; Chromatography, High Pressure Liquid; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Male; Microdialysis; N-Methylaspartate; Neurotoxins; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate	1995
Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzoates; Blood Pressure; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Male; Microinjections; N-Methylaspartate; Neurotoxins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Valine	1996
Heterologous modulation of inhibitory synaptic transmission by metabotropic glutamate receptors in cultured hippocampal neurons. Journal of neurophysiology, 1996, Volume: 75, Issue:2 Topics: Animals; Benzoates; Cells, Cultured; Cycloleucine; Dicarboxylic Acids; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Neural Inhibition; Neurons; Neurotransmitter Uptake Inhibitors; Patch-Clamp Techniques; Pyrrolidines; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission	1996
Contralateral turning caused by metabotropic glutamate receptor stimulation in the dorsal striatum is reversed by MCPG, TTX, and cis-flupenthixol. Behavioral neuroscience, 1996, Volume: 110, Issue:2 Topics: Animals; Benzoates; Corpus Striatum; Cycloleucine; Dominance, Cerebral; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Glycine; Male; Motor Activity; Neurons; Neurotoxins; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stereotyped Behavior; Synaptic Transmission; Tetrodotoxin	1996
Differences in agonist and antagonist activities for two indices of metabotropic glutamate receptor-stimulated phosphoinositide turnover. British journal of pharmacology, 1996, Volume: 117, Issue:8 Topics: Animals; Benzoates; Cerebral Cortex; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glycine; Inositol 1,4,5-Trisphosphate; Male; Molecular Conformation; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism	1996
Metabotropic glutamate receptors and visual cortical synaptic plasticity. Canadian journal of physiology and pharmacology, 1995, Volume: 73, Issue:9 Topics: Animals; Benzoates; Calcium; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Long-Term Potentiation; Male; Neuronal Plasticity; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Visual Cortex	1995
Metabotropic glutamate group II receptors are responsible for the depression of synaptic transmission induced by ACPD in the dentate gyrus. European journal of pharmacology, 1995, Dec-29, Volume: 294, Issue:2-3 Topics: Animals; Benzoates; Cycloleucine; Dentate Gyrus; Excitatory Amino Acid Antagonists; Glycine; Male; Rats; Rats, Wistar; Receptors, Glutamate; Synaptic Transmission	1995
1S,3R-ACPD dose dependently induces a slow onset potentiation in the dentate gyrus in vivo. European journal of pharmacology, 1995, Dec-29, Volume: 294, Issue:2-3 Topics: Action Potentials; Animals; Benzoates; Cycloleucine; Dentate Gyrus; Dose-Response Relationship, Drug; Glycine; Long-Term Potentiation; Male; Rats; Rats, Wistar; Synaptic Transmission	1995
Differential long-lasting potentiation of the NMDA and non-NMDA synaptic currents induced by metabotropic and NMDA receptor coactivation in cerebellar granule cells. The European journal of neuroscience, 1996, Volume: 8, Issue:6 Topics: Animals; Benzoates; Cerebellum; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Potentiation; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	1996
Activation of multiple metabotropic glutamate receptor subtypes prevents NMDA-induced excitotoxicity in rat hippocampal slices. The European journal of neuroscience, 1996, Volume: 8, Issue:7 Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neuroprotective Agents; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate	1996
Effects of metabotropic glutamate receptor agonists on excitatory and inhibitory transmissions in cultured rat hippocampal neurons. Brain research, 1995, Dec-24, Volume: 705, Issue:1-2 Topics: Animals; Animals, Newborn; Benzoates; Cells, Cultured; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Neural Inhibition; Neurons; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Synaptic Transmission	1995
G-protein activation by metabotropic glutamate receptors reduces spike frequency adaptation in neocortical neurons. Neuroscience, 1996, Volume: 75, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides	1996
Postsynaptic glutamate uptake in rat cerebellar Purkinje cells. The Journal of physiology, 1996, Dec-01, Volume: 497 ( Pt 2) Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ion Channel Gating; Kynurenic Acid; Membrane Potentials; Monosaccharide Transport Proteins; Neuroprotective Agents; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin	1996
Activation of pharmacologically distinct metabotropic glutamate receptors depresses reticulospinal-evoked monosynaptic EPSPs in the lamprey spinal cord. Journal of neurophysiology, 1996, Volume: 76, Issue:6 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Axons; Benzoates; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Lampreys; Neural Pathways; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Reticular Formation; Spinal Cord; Synaptic Transmission	1996
Characterization of metabotropic glutamate receptor-mediated nitric oxide production in vivo. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Biomarkers; Calcium Channels; Citrulline; Cycloleucine; Dantrolene; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Male; Microdialysis; Muscle Proteins; N-Methylaspartate; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Ryanodine Receptor Calcium Release Channel; Tetrodotoxin	1997
Dual action of metabotropic glutamate receptor agonists on neuronal excitability and synaptic transmission in spinal ventral horn neurons in vitro. Neuropharmacology, 1996, Volume: 35, Issue:12 Topics: Amino Acids, Dicarboxylic; Animals; Anterior Horn Cells; Benzoates; Cycloleucine; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Rats; Spinal Cord; Synaptic Transmission; Time Factors	1996
Regulation of excitatory input to inhibitory interneurons of the dentate gyrus during hypoxia. Journal of neurophysiology, 1997, Volume: 77, Issue:1 Topics: Animals; Benzoates; Cycloleucine; Dentate Gyrus; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hypoxia, Brain; In Vitro Techniques; Interneurons; Kinetics; Male; Membrane Potentials; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Synaptic Transmission	1997
The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception. Pain, 1996, Volume: 68, Issue:2-3 Topics: Aminobutyrates; Analysis of Variance; Animals; Benzoates; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Male; Pain; Rats; Receptors, Metabotropic Glutamate; Resorcinols	1996
Methamphetamine-induced sensitization of dopamine release via a metabotropic glutamate receptor mediated pathway in rat striatal slices. Japanese journal of pharmacology, 1997, Volume: 73, Issue:3 Topics: Analysis of Variance; Animals; Benzoates; Corpus Striatum; Cycloleucine; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraperitoneal; Male; Methamphetamine; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stereoisomerism	1997
Metabotropic glutamate receptor mediated long-term depression in developing hippocampus. Neuropharmacology, 1997, Volume: 36, Issue:6 Topics: Animals; Benzoates; Cycloleucine; Depression, Chemical; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Neuroprotective Agents; Nitrendipine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Theophylline	1997
Activation of group III metabotropic glutamate receptors depresses glutamatergic transmission at corticostriatal synapse. Neuropharmacology, 1997, Volume: 36, Issue:6 Topics: Aminobutyrates; Animals; Benzoates; Corpus Striatum; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Neural Inhibition; Neuroprotective Agents; Phosphoserine; Presynaptic Terminals; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission	1997
Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain. Journal of neurochemistry, 1997, Volume: 69, Issue:2 Topics: Amyloid beta-Protein Precursor; Benzoates; Cell Line; Cycloleucine; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Glycine; GTP-Binding Proteins; Humans; Melitten; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Protein Kinases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Transfection; Type C Phospholipases	1997
Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: in vivo studies with (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a new potent and selective antagonist. The European journal of neuroscience, 1997, Volume: 9, Issue:7 Topics: Animals; Benzoates; Caudate Nucleus; Corpus Striatum; Cyclic AMP; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate	1997
Changes in extracellular nitrite and nitrate levels after inhibition of glial metabolism with fluorocitrate. Brain research, 1997, Jul-11, Volume: 762, Issue:1-2 Topics: Aconitate Hydratase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzoates; Cerebellum; Citrates; Citric Acid Cycle; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; Male; N-Methylaspartate; Neuroglia; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Quinoxalines; Rats; Rats, Wistar; Substrate Specificity	1997
Is activation of the metabotropic glutamate receptors impaired in the hippocampal CA1 area of the aged rat? Hippocampus, 1997, Volume: 7, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses	1997
Excitation of rat subthalamic nucleus neurones in vitro by activation of a group I metabotropic glutamate receptor. Brain research, 1997, Aug-22, Volume: 766, Issue:1-2 Topics: Adenine Nucleotides; Affinity Labels; Animals; Benzoates; Cycloleucine; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Male; Neurons; Neuroprotective Agents; Pyridoxal; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Thalamic Nuclei	1997
Development of metabotropic glutamate receptor-mediated synaptic inhibition. Neuroreport, 1997, Sep-08, Volume: 8, Issue:13 Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission	1997
Effects of the metabotropic glutamate receptor antagonist MCPG on phosphoinositide turnover and synaptic plasticity in visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jan-01, Volume: 18, Issue:1 Topics: Action Potentials; Age Factors; Animals; Benzoates; Binding, Competitive; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Long-Term Potentiation; Neuronal Plasticity; Neuroprotective Agents; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Metabotropic Glutamate; Synapses; Visual Cortex	1998
(R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) fails to block long-term potentiation under urethane anaesthesia in vivo. Neuropharmacology, 1997, Volume: 36, Issue:10 Topics: Analysis of Variance; Anesthesia; Anesthetics, Intravenous; Animals; Benzoates; Body Temperature; Brain; Cycloleucine; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Male; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Tetanus; Time Factors; Urethane	1997
Transmitter regulation of plateau properties in turtle motoneurons. Journal of neurophysiology, 1998, Volume: 79, Issue:1 Topics: Animals; Atropine; Baclofen; Benzoates; Calcium Channels; Calcium Channels, L-Type; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; Muscarine; Nifedipine; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Tetraethylammonium; Tetrodotoxin; Turtles	1998
Evidence for neuronal origin and metabotropic receptor-mediated regulation of extracellular glutamate and aspartate in rat striatum in vivo following electrical stimulation of the prefrontal cortex. Journal of neurochemistry, 1998, Volume: 70, Issue:2 Topics: Animals; Aspartic Acid; Benzoates; Calcium; Corpus Striatum; Cycloleucine; Dicarboxylic Acids; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycine; Male; Neurons; Neurotransmitter Uptake Inhibitors; Prefrontal Cortex; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tetrodotoxin; Time Factors	1998
In vivo microdialysis reveals facilitatory metabotropic glutamate receptors regulating excitatory amino acid release in rat nucleus tractus solitarius. Neurochemistry international, 1998, Volume: 32, Issue:1 Topics: Animals; Aspartic Acid; Benzoates; Calcium; Chromatography, High Pressure Liquid; Cycloleucine; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Glycine; Kinetics; Male; Microdialysis; Neurotoxins; Rats; Rats, Inbred WKY; Receptors, Metabotropic Glutamate; Solitary Nucleus; Tetrodotoxin	1998
Characterization of an intracellular alkaline shift in rat astrocytes triggered by metabotropic glutamate receptors. Journal of neurophysiology, 1998, Volume: 79, Issue:2 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Chloro-7-nitrobenzofurazan; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Animals, Newborn; Anti-Bacterial Agents; Astrocytes; Benzoates; Caffeine; Calcium; Cells, Cultured; Chlorides; Cycloleucine; Dicyclohexylcarbodiimide; Enzyme Inhibitors; Glycine; HEPES; Hydrogen-Ion Concentration; Indans; Intracellular Fluid; Ion Transport; Ionomycin; Ionophores; Macrolides; Nigericin; Rats; Receptors, Metabotropic Glutamate; Sodium	1998
(+)-MCPG blocks induction of LTP in CA1 of rat hippocampus via agonist action at an mGluR group II receptor. Journal of neurophysiology, 1998, Volume: 79, Issue:3 Topics: Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neuroprotective Agents; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate	1998
Metabotropic glutamate receptors depress glutamate-mediated synaptic input to rat midbrain dopamine neurones in vitro. British journal of pharmacology, 1998, Volume: 123, Issue:4 Topics: Alanine; Animals; Benzoates; Cycloleucine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamates; Glycine; In Vitro Techniques; Male; Mesencephalon; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate	1998
Group II and III metabotropic glutamate receptors modulate paired pulse depression in the rat dentate gyrus in vitro. European journal of pharmacology, 1997, Dec-04, Volume: 340, Issue:1 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Cycloleucine; Cyclopropanes; Dentate Gyrus; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Resorcinols	1997
Regulation of immediate early gene c-fos and zif/268 mRNA expression in rat striatum by metabotropic glutamate receptor. Brain research. Molecular brain research, 1998, Jun-01, Volume: 57, Issue:1 Topics: Animals; Benzazepines; Benzoates; Corpus Striatum; Cycloleucine; DNA-Binding Proteins; Dopamine Antagonists; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Excitatory Amino Acid Antagonists; Gene Expression; Genes, Immediate-Early; Glycine; Immediate-Early Proteins; In Situ Hybridization; Male; Microinjections; Neuroprotective Agents; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Metabotropic Glutamate; RNA, Messenger; Transcription Factors; Zinc Fingers	1998
Evidence for metabotropic glutamate receptor activation in the induction of depolarization-induced suppression of inhibition in hippocampal CA1. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jul-01, Volume: 18, Issue:13 Topics: 4-Aminopyridine; Amino Acids, Dicarboxylic; Animals; Benzoates; Calcium Channels; Cycloleucine; Cyclopropanes; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Male; Membrane Potentials; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Signal Transduction; Synapses	1998
Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4-carboxy-phenylglycine. Neuroscience, 1998, Volume: 85, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; N-Methylaspartate; Naphthols; Neurons, Afferent; Neuroprotective Agents; Propylene Glycols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus	1998
Progression of change in NMDA, non-NMDA, and metabotropic glutamate receptor function at the developing corticothalamic synapse. Journal of neurophysiology, 1998, Volume: 80, Issue:1 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Mice; Mice, Inbred ICR; Nerve Fibers; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Thalamus	1998
Metabotropic glutamate receptor activation modulates sound level processing in the cochlear nucleus. Journal of neurophysiology, 1998, Volume: 80, Issue:1 Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Auditory Perception; Benzoates; Cats; Cochlear Nucleus; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; N-Methylaspartate; Neurons; Neuroprotective Agents; Receptors, Metabotropic Glutamate; Time Factors	1998
The metabotropic glutamate receptor antagonist (RS)-MCPG produces hyperlocomotion in amphetamine pre-exposed rats. Neuropharmacology, 1998, Volume: 37, Issue:2 Topics: Amphetamine; Animals; Benzoates; Central Nervous System Stimulants; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraventricular; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate	1998
Effects of metabotropic glutamate receptor block on the synaptic transmission and plasticity in the rat medial vestibular nuclei. Neuroscience, 1998, Volume: 87, Issue:1 Topics: Animals; Benzoates; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Potentiation; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Vestibular Nuclei	1998
Regulation of intrinsic and synaptic properties of neonatal rat trigeminal motoneurons by metabotropic glutamate receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Nov-15, Volume: 18, Issue:22 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Trigeminal Nuclei	1998
Group I mGluRs modulate calcium currents in rat GP: functional implications. Synapse (New York, N.Y.), 1998, Volume: 30, Issue:4 Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cycloleucine; Electric Conductivity; Excitatory Amino Acid Antagonists; Globus Pallidus; Glycine; Male; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols	1998
Metabotropic glutamate receptor agonist (1S,3R-ACPD) increased frontal cortex dopamine release in aged but not in young rats. European journal of pharmacology, 1998, Oct-23, Volume: 359, Issue:2-3 Topics: Animals; Benzoates; Cycloleucine; Dopamine; Excitatory Amino Acid Antagonists; Frontal Lobe; Glycine; Male; Microdialysis; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Time Factors	1998
Role of group I metabotropic glutamate receptors in traumatic spinal cord white matter injury. Journal of neurotrauma, 1998, Volume: 15, Issue:11 Topics: Age Factors; Animals; Astrocytes; Benzoates; Cycloleucine; Electrophysiology; Estrenes; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glycine; Immunohistochemistry; Male; Membrane Potentials; Nerve Fibers; Neuroprotective Agents; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Spinal Cord Injuries; Type C Phospholipases	1998
Membrane potential and intracellular Ca2+ oscillations activated by mGluRs in hippocampal stratum oriens/alveus interneurons. Journal of neurophysiology, 1999, Volume: 81, Issue:1 Topics: Animals; Benzoates; Calcium; Calcium Signaling; Cycloleucine; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Image Processing, Computer-Assisted; In Vitro Techniques; Interneurons; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tetrodotoxin	1999
Mechanisms involved in the metabotropic glutamate receptor-enhancement of NMDA-mediated motoneurone responses in frog spinal cord. British journal of pharmacology, 1999, Volume: 126, Issue:1 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chlorpromazine; Cycloleucine; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; GTP-Binding Proteins; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Pertussis Toxin; Rana pipiens; Receptors, Metabotropic Glutamate; Reflex; Resorcinols; Second Messenger Systems; Spinal Cord; Sulfonamides; Tetrodotoxin; Thapsigargin; Virulence Factors, Bordetella	1999
Evidence that a novel metabotropic glutamate receptor mediates the induction of long-term potentiation at CA1 synapses in the hippocampus. Biochemical Society transactions, 1999, Volume: 27, Issue:2 Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Synapses	1999
Group I metabotropic glutamate receptors mediate phospholipase D stimulation in rat cultured astrocytes. Journal of neurochemistry, 1999, Volume: 72, Issue:4 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Benzoates; Carcinogens; Cerebellum; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Neurons; Neuroprotective Agents; Norepinephrine; Phospholipase D; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sympathomimetics; Tetradecanoylphorbol Acetate; Type C Phospholipases	1999
Expression and signaling of group I metabotropic glutamate receptors in astrocytes and microglia. Journal of neurochemistry, 1999, Volume: 72, Issue:4 Topics: Animals; Astrocytes; Benzoates; Brain; Brain Chemistry; Calcium; Cells, Cultured; Cycloleucine; DNA Primers; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Glycine; In Situ Hybridization; Inositol 1,4,5-Trisphosphate; Microglia; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction	1999
Glutamate regulates IP3-type and CICR stores in the avian cochlear nucleus. Journal of neurophysiology, 1999, Volume: 81, Issue:4 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alanine; Animals; Benzoates; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Chelating Agents; Chick Embryo; Cochlear Nucleus; Cyclic AMP; Cycloleucine; Cysteine; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Gallic Acid; Glutamic Acid; Glycine; Ibotenic Acid; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Receptors, Cytoplasmic and Nuclear; Ryanodine; Second Messenger Systems; Thionucleotides	1999
ACPD-mediated slow-onset potentiation is associated with cell death in the rat CA1 region in vivo. Neuropharmacology, 1999, Volume: 38, Issue:4 Topics: Animals; Benzoates; Cell Death; Cell Survival; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Neuronal Plasticity; Neuroprotective Agents; Rats; Rats, Wistar	1999
Cardiovascular response to group I metabotropic glutamate receptor activation in NTS. The American journal of physiology, 1999, Volume: 276, Issue:5 Topics: Animals; Baroreflex; Benzoates; Blood Pressure; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Kynurenic Acid; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sympathetic Nervous System	1999
Differential effects of metabotropic glutamate receptor antagonists on bursting activity in the amygdala. Journal of neurophysiology, 1999, Volume: 81, Issue:5 Topics: Amygdala; Animals; Benzoates; Cycloleucine; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kindling, Neurologic; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses	1999
Regulation of NMDA-stimulated [14C]GABA and [3H]acetylcholine release by striatal glutamate and dopamine receptors. Brain research, 1999, Oct-09, Volume: 844, Issue:1-2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Carbon Radioisotopes; Corpus Striatum; Cycloleucine; Dopamine Agonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Male; N-Methylaspartate; Proline; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium	1999
The retention deficit induced by (RS)-alpha-methyl-4-carboxyphenylglycine in a lever-press learning task is blocked by selective agonists of either group I or group II metabotropic glutamate receptors. Experimental brain research, 1999, Volume: 129, Issue:1 Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cycloleucine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Learning; Male; Memory Disorders; Mice; Mice, Inbred Strains; Neuroprotective Agents; Protein Isoforms; Receptors, Metabotropic Glutamate; Resorcinols; Retention, Psychology; Time Factors	1999
Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Nov-15, Volume: 19, Issue:22 Topics: Animals; Benzoates; Cycloleucine; Dopamine; Electric Stimulation; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Indans; Kinetics; Male; Mitogen-Activated Protein Kinases; Models, Neurological; Neuronal Plasticity; Phosphoserine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate	1999
Potentiation of glutamatergic agonist-induced inositol phosphate formation by basic fibroblast growth factor is related to developmental features in hippocampal cultures: neuronal survival and glial cell proliferation. The European journal of neuroscience, 1999, Volume: 11, Issue:10 Topics: Animals; Antimetabolites, Antineoplastic; Benzoates; Cell Division; Cell Survival; Cells, Cultured; Cellular Senescence; Cycloleucine; Cytarabine; Epidermal Growth Factor; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Fibroblast Growth Factor 2; Glutamic Acid; Glycine; Hippocampus; Inositol Phosphates; Neuroglia; Neurons; Neuroprotective Agents; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Type C Phospholipases	1999
Group II metabotropic glutamate receptors are a common target of N-anisoyl-GABA and 1S,3R-ACPD in enhancing ACh release in the prefrontal cortex of freely moving SHRSP. Neuropharmacology, 2000, Mar-03, Volume: 39, Issue:5 Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Anisoles; Benzoates; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Indans; Male; Microdialysis; Perfusion; Prefrontal Cortex; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, AMPA; Receptors, Metabotropic Glutamate; Thalamic Nuclei; Wakefulness	2000
Neuroprotection by metabotropic glutamate receptor agonists on kainate-induced degeneration of motor neurons in spinal cord slices from adult rat. Neuropharmacology, 2000, Mar-03, Volume: 39, Issue:5 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Cell Survival; Choline O-Acetyltransferase; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Situ Nick-End Labeling; In Vitro Techniques; Kainic Acid; Male; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord	2000
(+)-MCPG induces PKCepsilon translocation in cortical synaptosomes through a PLD-coupled mGluR. The European journal of neuroscience, 2000, Volume: 12, Issue:4 Topics: Animals; Benzoates; Cerebral Cortex; Chelating Agents; Cycloleucine; Cyclopropanes; Egtazic Acid; Enzyme Activation; Excitatory Amino Acid Antagonists; Glycine; Isoenzymes; Male; Neurons; Neuroprotective Agents; Phospholipase D; Presynaptic Terminals; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptosomes	2000
Differential expression of group I metabotropic glutamate receptors in functionally distinct hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, May-15, Volume: 20, Issue:10 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression; Glycine; Hippocampus; Interneurons; Neuroprotective Agents; Patch-Clamp Techniques; Periodicity; Picrotoxin; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Tetrodotoxin	2000
Activation of metabotropic glutamate receptors induces gamma frequency oscillations in the rat dentate gyrus in vivo. Neuropharmacology, 2001, Volume: 40, Issue:4 Topics: Animals; Benzoates; Cycloleucine; Dentate Gyrus; Electroencephalography; Excitatory Amino Acid Antagonists; Glycine; Male; Rats; Receptors, Metabotropic Glutamate; Time Factors	2001
Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists. Journal of neuroendocrinology, 2001, Volume: 13, Issue:8 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Amino Acids; Animals; Benzoates; Bridged Bicyclo Compounds; Corticosterone; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Phenylacetates; Propionates; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Xanthenes	2001
Visualization of IP(3) dynamics reveals a novel AMPA receptor-triggered IP(3) production pathway mediated by voltage-dependent Ca(2+) influx in Purkinje cells. Neuron, 2001, Oct-11, Volume: 32, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Blood Proteins; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cycloleucine; Cytoplasm; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Vectors; Glutamic Acid; Glycine; Green Fluorescent Proteins; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred ICR; Neuroprotective Agents; Patch-Clamp Techniques; Phosphoproteins; Purkinje Cells; Receptors, AMPA; Receptors, Metabotropic Glutamate; Sindbis Virus	2001
Group I metabotropic glutamate receptor-mediated enhancement of dopamine cell burst firing in rat ventral tegmental area in vitro. Brain research, 2002, Sep-06, Volume: 948, Issue:1-2 Topics: Action Potentials; Animals; Apamin; Benzoates; Biological Clocks; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Ventral Tegmental Area	2002
Activation of glutamate receptors inhibits Na/K-ATPase of cerebellum granule cells. Biochemistry. Biokhimiia, 2002, Volume: 67, Issue:9 Topics: Alkaloids; Animals; Benzoates; Benzophenanthridines; Cerebellum; Cycloleucine; Cysteine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Glycine; Male; Mice; Mice, Inbred AKR; N-Methylaspartate; Neurons; Phenanthridines; Receptors, Glutamate; Sodium-Potassium-Exchanging ATPase	2002
Antagonism of glutamatergic metabotropic receptors in the NTS of awake rats does not affect the gain of the baroreflex. Autonomic neuroscience : basic & clinical, 2003, Jan-31, Volume: 103, Issue:1-2 Topics: Animals; Baroreflex; Benzoates; Blood Pressure; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Heart Rate; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Solitary Nucleus	2003
Actions of Group I and Group II metabotropic glutamate receptor ligands on 5-hydroxytryptamine release in the rat cerebral cortex in vivo: differential roles in the regulation of central serotonergic neurotransmission. Neuroscience, 2003, Volume: 117, Issue:3 Topics: Amino Acids, Dicarboxylic; Analysis of Variance; Anesthetics, Local; Animals; Benzoates; Calcium; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Ligands; Male; Microdialysis; Potassium Chloride; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Serotonin; Synaptic Transmission; Tetrodotoxin	2003
Comparison of metabotropic glutamate receptor responses at segmental and descending inputs to motoneurons in neonatal rat spinal cord. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Benzoates; Brain-Derived Neurotrophic Factor; Cycloleucine; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Motor Neurons; Neurotrophin 3; Patch-Clamp Techniques; Phosphinic Acids; Rats; Receptors, Metabotropic Glutamate; Spinal Cord; Spinal Nerve Roots	2005
Nucleus- and species-specific properties of the slow (<1 Hz) sleep oscillation in thalamocortical neurons. Neuroscience, 2006, Aug-25, Volume: 141, Issue:2 Topics: Action Potentials; Animals; Benzoates; Cats; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons; Periodicity; Rats; Rats, Wistar; Sleep Stages; Species Specificity; Thalamic Nuclei	2006