Compounds > 1-amino-1,3-dicarboxycyclopentane

1-amino-1,3-dicarboxycyclopentane and 3,5-dihydroxyphenylglycine

1-amino-1,3-dicarboxycyclopentane has been researched along with 3,5-dihydroxyphenylglycine in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	45 (71.43)	18.2507
2000's	16 (25.40)	29.6817
2010's	2 (3.17)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Adam, G; Bleuel, Z; Chaboz, S; Ellis, GJ; Faull, RL; Malherbe, P; Messer, J; Metzler, V; Mutel, V; Nilly, A; Richards, JG; Roughley, BS; Schlaeger, EJ	1
Bischoff, F; Janssen, C; Langlois, X; Lavreysen, H; Lesage, AS; Leysen, JE	1
Hayashi, M; Hirose, E; Ito, I; Kohda, A; Mitsunaga, S; Sugiyama, H; Tanabe, S	1
Baker, SR; Goldsworthy, JS; Johnson, BG; Salhoff, CR; Schoepp, DD; Wright, RA	1
Conn, PJ; Winder, DG	1
Baker, SR; Goldsworthy, J; Johnson, BG; Salhoff, CR; Schoepp, DD	1
Headley, PM; Jones, MW	1
Alexander, SP; Kendall, DA; Neil, KE	1
Johnson, BG; Monn, JA; Schoepp, DD	1
DiMicco, J; Monroe, AJ	1
Burnett, JP; Desai, MA; Mayne, NG; Schoepp, DD	1
Belagaje, R; Burnett, JP; Johnson, BG; Mayne, NG; Monn, JA; Salhoff, CR; Schoepp, DD; Wright, RA; Wu, S	1
Coderre, TJ; Fisher, K	1
Bernardi, G; Calabresi, P; Centonze, D; Pisani, A	1
Albin, RL; Frey, KA; Kearney, JA	1
de Mendonça, A; Ribeiro, JA	1
Bordi, F; Corsi, M; Ugolini, A	1
Abbott, A; Lacey, MG; Wigmore, MA	1
DiJulio, N; Gruol, DL; Parsons, KL	1
Hounsgaard, J; Svirskis, G	1
Birch, PJ; Blackburn-Munro, G; Bountra, C; Dickinson, T; Fleetwood-Walker, SM; Sparrow, H; Young, MR	1
Camón, L; de Vera, N; Martínez, E; Vives, P	1
Cassidy, EM; O'Connor, JJ; O'Leary, DM	1
Abraham, WC; Cohen, AS; Raymond, CR	1
Balázs, R; Chun, Y; Cotman, CW; Miller, S; O'Toole, J	1
Alford, S; Cochilla, AJ	1
Dickenson, AH; Stanfa, LC	1
Carfì, M; Cozzi, A; Leonardi, P; Lombardi, G; Moroni, F; Pellicciari, R; Sourtcheva, S	1
Bijak, M; Brański, P; Pałucha, A; Pilc, A; Tokarski, K	1
Conn, PJ; Peavy, RD	1
Chu, Z; Hablitz, JJ	1
El Manira, A; Grillner, S; Krieger, P	1
Bernardi, G; Spadoni, F; Stefani, A	1
Agrawal, SK; Fehlings, MG; Theriault, E	1
Bortolotto, ZA; Collingridge, GL; Doherty, AJ; Fitzjohn, SM; Kingston, AE; Lodge, D; Ornstein, PL; Palmer, MJ; Schoepp, DD	1
Dalby, NO; Thomsen, C	1
Davidoff, RA; Hackman, JC; Holohean, AM	1
Chamberlain, M; Johnson, MP; Kelly, GM	1
Bortolotto, ZA; Collingridge, GL	1
Keele, NB; Neugebauer, V; Shinnick-Gallagher, P	1
Aggleton, JP; Bashir, ZI; Bortolotto, ZA; Brown, MW; Cho, K; Collingridge, GL; Conquet, F; McCaffery, B	1
Bernardi, G; Guatteo, E; Knöpfel, T; Mercuri, NB	1
Mathis, C; Ungerer, A	1
Herrero, I; Manahan-Vaughan, D; Reymann, KG; Sánchez-Prieto, J	1
Kaasik, A; Kalda, A; Pokk, P; Vassiljev, V; Zharkovsky, A	1
Bacon, G; Chen, Y; Clark, BP; Johnson, BG; Kallman, MJ; Kingston, AE; Schoepp, DD; Sher, E; Wright, RA	1
Dolan, S; Nolan, AM	1
Wiśniewski, K; Zalewska-Wińska, A	1
Nagy, F; Voisin, DL	1
Gleason, EL; Kreimborg, KM; Lester, ML; Medler, KF	1
Haworth, RA; Schomberg, SL; Su, G; Sun, D	1
Morsette, DJ; Sidorowicz, H; Sladek, CD	1
Chamberlain, M; Johnson, MP; Kelly, G	1
Johnson, SW; Zheng, F	1
Alreja, M; Hajszan, T; Leranth, C; Wu, M	1
Beltramo, M; Brusa, R; Lozza, G; Mancini, I; Petrò, R; Reggiani, A; Scandroglio, P	1
Charles, JR; Duva, MA; Lara, RL; Ramirez, GJ; Stanley, BG; Yang, CR	1
Acher, FC; Brabet, I; Jullian, N; Pin, JP	1
Costantino, G; Marinozzi, M; Moroni, F; Natalini, B; Pellegrini-Giampietro, D; Pellicciari, R	1
Costantino, G; Macchiarulo, A; Pellicciari, R	1
Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO	1
Acher, F; Bertrand, HO; Brabet, I; Pin, JP; Triballeau, N	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1

Reviews

1 review(s) available for 1-amino-1,3-dicarboxycyclopentane and 3,5-dihydroxyphenylglycine

Article	Year
Ligands for glutamate receptors: design and therapeutic prospects. Journal of medicinal chemistry, 2000, Jul-13, Volume: 43, Issue:14 Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses	2000

Other Studies

62 other study(ies) available for 1-amino-1,3-dicarboxycyclopentane and 3,5-dihydroxyphenylglycine

Article	Year
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections. Journal of neurochemistry, 2000, Volume: 75, Issue:6 Topics: Animals; Binding, Competitive; Brain; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Imidazoles; Indans; Intracellular Fluid; Kainic Acid; Male; Organ Specificity; Quinazolines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spinal Cord; Transfection	2000
[3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists. Molecular pharmacology, 2003, Volume: 63, Issue:5 Topics: Adamantane; Allosteric Regulation; Animals; Binding Sites; Binding, Competitive; Brain; Cell Line; Cell Membrane; CHO Cells; Chromones; Cricetinae; Humans; Naphthalenes; Pyrans; Quinolines; Quinoxalines; Quisqualic Acid; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Transfection; Tritium	2003
3,5-Dihydroxyphenyl-glycine: a potent agonist of metabotropic glutamate receptors. Neuroreport, 1992, Volume: 3, Issue:11 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cycloleucine; Egtazic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Oocytes; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Resorcinols; RNA, Messenger; Xenopus	1992
Second-messenger responses in brain slices to elucidate novel glutamate receptors. Journal of neuroscience methods, 1995, Volume: 59, Issue:1 Topics: Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Guinea Pigs; Hippocampus; Rats; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Resorcinols; Second Messenger Systems	1995
Metabotropic glutamate receptor (mGluR)-mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR. Journal of neurochemistry, 1995, Volume: 64, Issue:2 Topics: Animals; Brain; Calcium; Calcium-Transporting ATPases; Cyclic AMP; Cycloleucine; Glycine; Hydrolysis; In Vitro Techniques; Intracellular Membranes; Neurotoxins; Phosphatidylinositols; Protein Kinase C; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Terpenes; Thapsigargin	1995
3,5-dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus. Journal of neurochemistry, 1994, Volume: 63, Issue:2 Topics: Aging; Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Colforsin; Cyclic AMP; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Kinetics; Male; Neurotoxins; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Resorcinols; Second Messenger Systems	1994
Interactions between metabotropic and ionotropic glutamate receptor agonists in the rat spinal cord in vivo. Neuropharmacology, 1995, Volume: 34, Issue:8 Topics: Action Potentials; Animals; Blood Pressure; Cycloleucine; Electrophoresis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord	1995
Coupling of metabotropic glutamate receptors to phosphoinositide mobilisation and inhibition of cyclic AMP generation in the guinea-pig cerebellum. British journal of pharmacology, 1996, Volume: 118, Issue:2 Topics: 2-Chloroadenosine; Animals; Cerebellum; Colforsin; Cyclic AMP; Cycloleucine; Female; Glutamic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Phosphatidylinositols; Receptors, Metabotropic Glutamate; Resorcinols	1996
(1 S,3 R)-1-aminocyclopentane-1,3-dicarboxylic acid-induced increases in cyclic AMP formation in the neonatal rat hippocampus are mediated by a synergistic interaction between phosphoinositide- and inhibitory cyclic AMP-coupled mGluRs. Journal of neurochemistry, 1996, Volume: 66, Issue:5 Topics: Animals; Animals, Newborn; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols	1996
Stimulation of metabotropic glutamate receptors in the dorsomedial hypothalamus elevates heart rate in rats. The American journal of physiology, 1996, Volume: 270, Issue:5 Pt 2 Topics: 2-Amino-5-phosphonovalerate; Animals; Cycloleucine; Dose-Response Relationship, Drug; Glycine; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Tachycardia	1996
Pharmacological characterization of desensitization in a human mGlu1 alpha-expressing non-neuronal cell line co-transfected with a glutamate transporter. British journal of pharmacology, 1996, Volume: 118, Issue:6 Topics: Amino Acid Transport System X-AG; Animals; Carrier Proteins; Cell Line; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Glycoproteins; Humans; Hydrolysis; Inosine Triphosphate; Inositol; Neurotoxins; Phosphatidylinositols; Rats; Receptors, Metabotropic Glutamate; Resorcinols	1996
The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors. Neuropharmacology, 1996, Volume: 35, Issue:12 Topics: Aging; Animals; Animals, Newborn; Brain; Cloning, Molecular; Colforsin; Cyclic AMP; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Humans; Inositol; Kinetics; Neuroprotective Agents; Phosphatidylinositols; Proline; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Second Messenger Systems	1996
The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception. Pain, 1996, Volume: 68, Issue:2-3 Topics: Aminobutyrates; Analysis of Variance; Animals; Benzoates; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Male; Pain; Rats; Receptors, Metabotropic Glutamate; Resorcinols	1996
Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones. British journal of pharmacology, 1997, Volume: 120, Issue:6 Topics: Animals; Cycloleucine; Excitatory Amino Acid Agents; Glycine; Male; N-Methylaspartate; Neostriatum; Neurons; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols	1997
Metabotropic glutamate agonist-induced rotation: a pharmacological, FOS immunohistochemical, and [14C]-2-deoxyglucose autoradiographic study. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jun-01, Volume: 17, Issue:11 Topics: Animals; Autoradiography; Basal Ganglia; Behavior, Animal; Caffeine; Carbon Radioisotopes; Cycloleucine; Deoxyglucose; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Glucose; Glycine; Immunohistochemistry; Male; Neuroprotective Agents; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Receptors, Purinergic P1; Resorcinols; Rotation; Salicylamides; Thalamic Nuclei; Xanthines	1997
Influence of metabotropic glutamate receptor agonists on the inhibitory effects of adenosine A1 receptor activation in the rat hippocampus. British journal of pharmacology, 1997, Volume: 121, Issue:8 Topics: Adenosine; Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Resorcinols	1997
Potentiation of NMDA and AMPA responses by group I mGluR in spinal cord motoneurons. Neuropharmacology, 1997, Volume: 36, Issue:8 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; Motor Neurons; N-Methylaspartate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord	1997
Excitation of rat subthalamic nucleus neurones in vitro by activation of a group I metabotropic glutamate receptor. Brain research, 1997, Aug-22, Volume: 766, Issue:1-2 Topics: Adenine Nucleotides; Affinity Labels; Animals; Benzoates; Cycloleucine; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Male; Neurons; Neuroprotective Agents; Pyridoxal; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Thalamic Nuclei	1997
Acute ethanol alters calcium signals elicited by glutamate receptor agonists and K+ depolarization in cultured cerebellar Purkinje neurons. Brain research, 1997, Oct-31, Volume: 773, Issue:1-2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebellar Cortex; Cycloleucine; Embryo, Mammalian; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Membrane Potentials; Potassium; Purkinje Cells; Rats; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Resorcinols	1997
Transmitter regulation of plateau properties in turtle motoneurons. Journal of neurophysiology, 1998, Volume: 79, Issue:1 Topics: Animals; Atropine; Baclofen; Benzoates; Calcium Channels; Calcium Channels, L-Type; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; Muscarine; Nifedipine; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Tetraethylammonium; Tetrodotoxin; Turtles	1998
Behavioural and electrophysiological evidence supporting a role for group I metabotropic glutamate receptors in the mediation of nociceptive inputs to the rat spinal cord. Brain research, 1997, Nov-28, Volume: 777, Issue:1-2 Topics: Alanine; Animals; Antihypertensive Agents; Behavior, Animal; Benzothiadiazines; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Glycine; Male; Mustard Plant; Neuroprotective Agents; Nociceptors; Pain; Phenylacetates; Plant Extracts; Plant Oils; Plants, Medicinal; Rats; Rats, Inbred Strains; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord	1997
Seizures and neuronal damage induced in the rat by activation of group I metabotropic glutamate receptors with their selective agonist 3,5-dihydroxyphenylglycine. Journal of neuroscience research, 1998, Feb-01, Volume: 51, Issue:3 Topics: Analysis of Variance; Animals; Cerebral Ventricles; Cycloleucine; Excitatory Amino Acid Agonists; Glycine; Infusions, Parenteral; Male; Motor Activity; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Seizures	1998
Group II and III metabotropic glutamate receptors modulate paired pulse depression in the rat dentate gyrus in vitro. European journal of pharmacology, 1997, Dec-04, Volume: 340, Issue:1 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Cycloleucine; Cyclopropanes; Dentate Gyrus; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Resorcinols	1997
Priming of long-term potentiation induced by activation of metabotropic glutamate receptors coupled to phospholipase C. Hippocampus, 1998, Volume: 8, Issue:2 Topics: Animals; Cycloleucine; Electric Stimulation; Estrenes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neuroprotective Agents; Pyramidal Cells; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Type C Phospholipases	1998
Metabotropic glutamate receptor agonists potentiate cyclic AMP formation induced by forskolin or beta-adrenergic receptor activation in cerebral cortical astrocytes in culture. Journal of neurochemistry, 1998, Volume: 70, Issue:6 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Cycloleucine; Drug Synergism; Estrenes; Excitatory Amino Acid Agonists; Glycine; Neocortex; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Adrenergic, beta; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Type C Phospholipases; Up-Regulation	1998
Metabotropic glutamate receptor-mediated control of neurotransmitter release. Neuron, 1998, Volume: 20, Issue:5 Topics: 4-Aminopyridine; Animals; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Lampreys; Membrane Potentials; Motor Neurons; Neuroprotective Agents; Neurotransmitter Agents; Potassium; Presynaptic Terminals; Receptors, Metabotropic Glutamate; Resorcinols; Ryanodine; Spinal Cord; Synaptic Transmission	1998
Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones. European journal of pharmacology, 1998, Apr-24, Volume: 347, Issue:2-3 Topics: Animals; Carrageenan; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Inflammation; Male; Neurons; Pain; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Supine Position	1998
Presynaptic mGlu1 type receptors potentiate transmitter output in the rat cortex. European journal of pharmacology, 1998, Apr-24, Volume: 347, Issue:2-3 Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indans; Microdialysis; Parietal Lobe; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Resorcinols	1998
Antidepressant treatment influences group I of glutamate metabotropic receptors in slices from hippocampal CA1 region. European journal of pharmacology, 1998, May-15, Volume: 349, Issue:1 Topics: Action Potentials; Animals; Antidepressive Agents, Tricyclic; Cycloleucine; Electroshock; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Imipramine; Inositol Phosphates; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols	1998
Phosphorylation of mitogen-activated protein kinase in cultured rat cortical glia by stimulation of metabotropic glutamate receptors. Journal of neurochemistry, 1998, Volume: 71, Issue:2 Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Glycine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Neuroglia; Neuroprotective Agents; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Tyrosine	1998
Activation of group I mGluRs increases spontaneous IPSC frequency in rat frontal cortex. Journal of neurophysiology, 1998, Volume: 80, Issue:2 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Frontal Lobe; Glycine; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Tetrodotoxin	1998
Endogenous activation of metabotropic glutamate receptors contributes to burst frequency regulation in the lamprey locomotor network. The European journal of neuroscience, 1998, Volume: 10, Issue:11 Topics: Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Lampreys; Locomotion; Membrane Potentials; N-Methylaspartate; Nerve Net; Periodicity; Propionates; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Synaptic Transmission	1998
Group I mGluRs modulate calcium currents in rat GP: functional implications. Synapse (New York, N.Y.), 1998, Volume: 30, Issue:4 Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cycloleucine; Electric Conductivity; Excitatory Amino Acid Antagonists; Globus Pallidus; Glycine; Male; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols	1998
Role of group I metabotropic glutamate receptors in traumatic spinal cord white matter injury. Journal of neurotrauma, 1998, Volume: 15, Issue:11 Topics: Age Factors; Animals; Astrocytes; Benzoates; Cycloleucine; Electrophysiology; Estrenes; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glycine; Immunohistochemistry; Male; Membrane Potentials; Nerve Fibers; Neuroprotective Agents; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Spinal Cord Injuries; Type C Phospholipases	1998
The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity. Neuropharmacology, 1998, Volume: 37, Issue:12 Topics: Aging; Amino Acids; Animals; Binding, Competitive; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Neuronal Plasticity; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Transfection; Xanthenes	1998
Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetrazole-induced seizure activity in mice. Neuropharmacology, 1998, Volume: 37, Issue:12 Topics: Animals; Cerebral Ventricles; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Indans; Infusions, Parenteral; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Reaction Time; Resorcinols; Seizures	1998
Mechanisms involved in the metabotropic glutamate receptor-enhancement of NMDA-mediated motoneurone responses in frog spinal cord. British journal of pharmacology, 1999, Volume: 126, Issue:1 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chlorpromazine; Cycloleucine; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; GTP-Binding Proteins; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Pertussis Toxin; Rana pipiens; Receptors, Metabotropic Glutamate; Reflex; Resorcinols; Second Messenger Systems; Spinal Cord; Sulfonamides; Tetrodotoxin; Thapsigargin; Virulence Factors, Bordetella	1999
Phosphoinositide hydrolysis in vivo with group I metabotropic glutamate receptor agonists. Brain research, 1999, Mar-13, Volume: 821, Issue:2 Topics: Amino Acids; Animals; Brain Chemistry; Cerebellum; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Hydrolysis; Injections, Intraventricular; Male; Neuroprotective Agents; Phenylacetates; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Tritium; Type C Phospholipases; Xanthenes	1999
Evidence that a novel metabotropic glutamate receptor mediates the induction of long-term potentiation at CA1 synapses in the hippocampus. Biochemical Society transactions, 1999, Volume: 27, Issue:2 Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Synapses	1999
Differential effects of metabotropic glutamate receptor antagonists on bursting activity in the amygdala. Journal of neurophysiology, 1999, Volume: 81, Issue:5 Topics: Amygdala; Animals; Benzoates; Cycloleucine; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kindling, Neurologic; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses	1999
Synaptic depression induced by pharmacological activation of metabotropic glutamate receptors in the perirhinal cortex in vitro. Neuroscience, 1999, Volume: 93, Issue:3 Topics: Animals; Cycloleucine; Cyclopropanes; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; Neocortex; Neuronal Plasticity; Organ Culture Techniques; Propionates; Rats; Rats, Inbred Strains; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Temporal Lobe	1999
Group I metabotropic glutamate receptors mediate an inward current in rat substantia nigra dopamine neurons that is independent from calcium mobilization. Journal of neurophysiology, 1999, Volume: 82, Issue:4 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Chromones; Cycloleucine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Microscopy, Fluorescence; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Substantia Nigra; Tetrodotoxin; Thapsigargin	1999
The retention deficit induced by (RS)-alpha-methyl-4-carboxyphenylglycine in a lever-press learning task is blocked by selective agonists of either group I or group II metabotropic glutamate receptors. Experimental brain research, 1999, Volume: 129, Issue:1 Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cycloleucine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Learning; Male; Memory Disorders; Mice; Mice, Inbred Strains; Neuroprotective Agents; Protein Isoforms; Receptors, Metabotropic Glutamate; Resorcinols; Retention, Psychology; Time Factors	1999
Presynaptic group 1 metabotropic glutamate receptors may contribute to the expression of long-term potentiation in the hippocampal CA1 region. Neuroscience, 1999, Volume: 94, Issue:1 Topics: Animals; Azetidinecarboxylic Acid; Calcium; Cycloleucine; Dicarboxylic Acids; Diglycerides; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; Long-Term Potentiation; Male; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Presynaptic Terminals; Pyrrolidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptosomes	1999
Neuroprotective action of group I metabotropic glutamate receptor agonists against oxygen-glucose deprivation-induced neuronal death. Brain research, 2000, Jan-24, Volume: 853, Issue:2 Topics: Animals; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebellum; Cycloleucine; Electrophoresis, Agar Gel; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glucose; Glycine; In Situ Nick-End Labeling; Indans; Indoles; Maleimides; Neurons; Neuroprotective Agents; Protein Kinase C; Rats; Receptors, Metabotropic Glutamate; Resorcinols	2000
Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl)propionic acid) in the in vitro neonatal spinal cord and in an in vivo pain model. Neuroscience, 2000, Volume: 95, Issue:3 Topics: Acetic Acid; Animals; Animals, Newborn; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Mice; Motor Neurons; Neuroprotective Agents; Nociceptors; Pain; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Spinal Nerve Roots; Stereoisomerism	2000
Behavioural evidence supporting a differential role for group I and II metabotropic glutamate receptors in spinal nociceptive transmission. Neuropharmacology, 2000, Apr-27, Volume: 39, Issue:7 Topics: Amino Acids, Dicarboxylic; Animals; Behavior, Animal; Chronic Disease; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Indans; Injections, Spinal; Nociceptors; Pain Threshold; Physical Stimulation; Receptors, Metabotropic Glutamate; Resorcinols; Sheep; Spinal Cord; Synaptic Transmission	2000
Behavioural activity of (S)-3,5-DHPG, a selective agonist of group I metabotropic glutamate receptors. Pharmacological research, 2000, Volume: 42, Issue:3 Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Cycloleucine; Exploratory Behavior; Glycine; Long-Term Potentiation; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols	2000
Sustained L-type calcium currents in dissociated deep dorsal horn neurons of the rat: characteristics and modulation. Neuroscience, 2001, Volume: 102, Issue:2 Topics: Animals; Baclofen; Barium; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols	2001
Group I metabotropic glutamate receptors are expressed in the chicken retina and by cultured retinal amacrine cells. Journal of neurochemistry, 2001, Volume: 77, Issue:2 Topics: Amino Acid Sequence; Animals; Antibody Specificity; Blotting, Western; Calcium Signaling; Cells, Cultured; Chickens; Cycloleucine; Excitatory Amino Acid Agonists; Eye Proteins; Fluorescent Antibody Technique, Indirect; gamma-Aminobutyric Acid; Glycine; Molecular Sequence Data; Molecular Weight; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Retina	2001
Stimulation of Na-K-2Cl cotransporter in neurons by activation of Non-NMDA ionotropic receptor and group-I mGluRs. Journal of neurophysiology, 2001, Volume: 85, Issue:6 Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Carrier Proteins; Cells, Cultured; Chromones; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fetus; Glycine; Neurons; Neuroprotective Agents; Phosphorylation; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters	2001
Role of metabotropic glutamate receptors in vasopressin and oxytocin release. American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:2 Topics: Aminobutyrates; Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hypothalamo-Hypophyseal System; In Vitro Techniques; Indans; Male; Neurons; Neuroprotective Agents; Osmolar Concentration; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Vasopressins	2001
Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists. Journal of neuroendocrinology, 2001, Volume: 13, Issue:8 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Amino Acids; Animals; Benzoates; Bridged Bicyclo Compounds; Corticosterone; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Phenylacetates; Propionates; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Xanthenes	2001
Group I metabotropic glutamate receptor-mediated enhancement of dopamine cell burst firing in rat ventral tegmental area in vitro. Brain research, 2002, Sep-06, Volume: 948, Issue:1-2 Topics: Action Potentials; Animals; Apamin; Benzoates; Biological Clocks; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Ventral Tegmental Area	2002
Nicotine recruits a local glutamatergic circuit to excite septohippocampal GABAergic neurons. The European journal of neuroscience, 2003, Volume: 18, Issue:5 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Acyclovir; Animals; Animals, Newborn; Atropine; Bicuculline; Bungarotoxins; Carrier Proteins; Cell Count; Choline; Chromones; Cycloleucine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electric Conductivity; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Membrane Transport Proteins; Microscopy, Electron; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parvalbumins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Resorcinols; Septum of Brain; Synapses; Tetrodotoxin; Tubocurarine; Valine; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins	2003
Evaluation of cannabinoid receptor 2 and metabotropic glutamate receptor 1 functional responses using a cell impedance-based technology. Journal of biomolecular screening, 2010, Volume: 15, Issue:10 Topics: Analgesics; Animals; Benzimidazoles; Biological Assay; Calcium; Cannabinoids; CHO Cells; Chromones; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanols; Cycloleucine; Electric Impedance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indoles; Naphthalenes; Neuroprotective Agents; Quinolines; Quisqualic Acid; Receptor, Cannabinoid, CB2; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Thiazoles	2010
Activation of lateral hypothalamic mGlu1 and mGlu5 receptors elicits feeding in rats. Neuropharmacology, 2014, Volume: 79 Topics: Animals; Benzimidazoles; Benzopyrans; Cycloleucine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hypothalamus; Male; Phenylacetates; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Thiazoles; Time Factors	2014
Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: a different environment but similar recognition of an extended glutamate conformation. Journal of medicinal chemistry, 1999, May-06, Volume: 42, Issue:9 Topics: Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; Glutamates; Ligands; Models, Molecular; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship	1999
(2R,1'S,2'R,3'S)-2-(2'-Carboxy-3'-phenylcyclopropyl)glycine (PCCG-13), the first potent and selective competitive antagonist of phospholipase D-coupled metabotropic glutamate receptors: asymmetric synthesis and preliminary biological properties. Journal of medicinal chemistry, 1999, Jul-15, Volume: 42, Issue:14 Topics: Animals; Cycloleucine; Cyclopropanes; Glycerophospholipids; Glycine; Hippocampus; In Vitro Techniques; Phospholipase D; Rats; Receptors, Metabotropic Glutamate; Stereoisomerism; Type C Phospholipases	1999
Pharmacophore models of group I and group II metabotropic glutamate receptor agonists. Analysis of conformational, steric, and topological parameters affecting potency and selectivity. Journal of medicinal chemistry, 1999, Jul-29, Volume: 42, Issue:15 Topics: Excitatory Amino Acid Agonists; Ligands; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship	1999
Virtual screening workflow development guided by the "receiver operating characteristic" curve approach. Application to high-throughput docking on metabotropic glutamate receptor subtype 4. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Binding Sites; Databases, Factual; Drug Design; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, Metabotropic Glutamate; ROC Curve	2005
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007