1-amino-1,3-dicarboxycyclopentane and 2r,4r-4-aminopyrrolidine-2,4-dicarboxylate

1-amino-1,3-dicarboxycyclopentane has been researched along with 2r,4r-4-aminopyrrolidine-2,4-dicarboxylate in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bond, A; Campbell, JB; Griffey, K; Howe, T; Johnson, BG; Lodge, D; Monn, JA; Paschal, JW; Salhoff, CR; Schoepp, DD; Spangle, LA; Tizzano, JP; Valli, MJ; Wright, RA1
Acher, FC; Brabet, I; Jullian, N; Pin, JP1
Araldi, GL; Kozikowski, AP; Pshenichkin, S; Surina, E; Tückmantel, W; Wroblewski, JT1
Costantino, G; Macchiarulo, A; Pellicciari, R1
Arnold, MB; Johnson, BG; Ornstein, PL; Schoepp, DD; Wheeler, WJ; Wright, RA1
Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO1
Acher, F; Bertrand, HO; Brabet, I; Pin, JP; Triballeau, N1

Reviews

1 review(s) available for 1-amino-1,3-dicarboxycyclopentane and 2r,4r-4-aminopyrrolidine-2,4-dicarboxylate

ArticleYear
Ligands for glutamate receptors: design and therapeutic prospects.
    Journal of medicinal chemistry, 2000, Jul-13, Volume: 43, Issue:14

    Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses

2000

Other Studies

6 other study(ies) available for 1-amino-1,3-dicarboxycyclopentane and 2r,4r-4-aminopyrrolidine-2,4-dicarboxylate

ArticleYear
Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase.
    Journal of medicinal chemistry, 1996, Jul-19, Volume: 39, Issue:15

    Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Anticonvulsants; Cerebral Cortex; Colforsin; Cyclic AMP; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Hydrogen Bonding; Limbic System; Mice; Models, Molecular; Molecular Structure; Proline; Rats; Receptors, Metabotropic Glutamate; Seizures; Spinal Cord; Stereoisomerism

1996
Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: a different environment but similar recognition of an extended glutamate conformation.
    Journal of medicinal chemistry, 1999, May-06, Volume: 42, Issue:9

    Topics: Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; Glutamates; Ligands; Models, Molecular; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship

1999
1-amino-APDC, a partial agonist of group II metabotropic glutamate receptors with neuroprotective properties.
    Bioorganic & medicinal chemistry letters, 1999, Jun-21, Volume: 9, Issue:12

    Topics: Animals; Cell Death; CHO Cells; Cricetinae; Excitatory Amino Acid Agonists; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Proline; Receptors, Metabotropic Glutamate

1999
Pharmacophore models of group I and group II metabotropic glutamate receptor agonists. Analysis of conformational, steric, and topological parameters affecting potency and selectivity.
    Journal of medicinal chemistry, 1999, Jul-29, Volume: 42, Issue:15

    Topics: Excitatory Amino Acid Agonists; Ligands; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship

1999
[3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells.
    Neuropharmacology, 1999, Volume: 38, Issue:10

    Topics: Amino Acids; Animals; Binding, Competitive; Calcium; Cell Membrane; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Kinetics; Radioligand Assay; Receptors, Metabotropic Glutamate; Recombinant Proteins; Transfection; Tritium; Xanthenes

1999
Virtual screening workflow development guided by the "receiver operating characteristic" curve approach. Application to high-throughput docking on metabotropic glutamate receptor subtype 4.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Binding Sites; Databases, Factual; Drug Design; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, Metabotropic Glutamate; ROC Curve

2005