Compounds > 1-amino-1,3-dicarboxycyclopentane

1-amino-1,3-dicarboxycyclopentane and 2-amino-4-phosphonobutyric acid

1-amino-1,3-dicarboxycyclopentane has been researched along with 2-amino-4-phosphonobutyric acid in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.86)	18.7374
1990's	57 (81.43)	18.2507
2000's	11 (15.71)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Araldi, GL; Kozikowski, AP; Pshenichkin, S; Steensma, D; Surina, E; Tückmantel, W; Wang, S; Wroblewski, JT	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Gallagher, JP; Zheng, F	1
Rainnie, DG; Shinnick-Gallagher, P	1
Baskys, A; Malenka, RC	1
Cotman, CW; Whittemore, ER	1
Cotman, CW; Monaghan, DT; Palmer, E	1
Miller, RF; Slaughter, MM	1
Griffey, KI; Schoepp, DD; Tizzano, JP	1
Miller, RF; Thoreson, WB	2
Herrera, AJ; Osborne, NN	1
Cavanni, P; Eistetter, H; Ferraguti, F; Ratti, E; Salvagno, C; Trist, DG	1
Boatright, JH; Gordon, JR; Iuvone, PM	1
Hansson, E; Johansson, BB; Rönnbäck, L; Westergren, I	1
Brotchie, JM; East, SJ; Hill, MP	1
Bau, A; Faarup, P; Foged, C; Kanstrup, A; Suzdak, PD; Thomsen, C	1
Battaglia, G; Bruno, V; Copani, A; Leanza, G; Nicoletti, F; Pellitteri, R; Russo, A; Stanzani, S	1
Becker, T; de Barry, J; Gombos, G	1
Bigl, V; Grantyn, R; Rothe, T	1
Slaughter, MM; Tian, N	1
Burke, JP; Hablitz, JJ	2
Cahusac, PM	1
Alexander, SP; Cartmell, J; Kemp, JA; Kendall, DA; Shinozaki, H	1
Hölscher, C	1
Cotman, CW; Kahle, JS	1
Jane, D; Jones, A; Jones, P; Kemp, M; Pook, P; Roberts, P; Sunter, D; Udvarhelyi, P; Watkins, J	1
Cahusac, PM; Taylor, KE	1
Bernardi, G; Calabresi, P; Mercuri, NB; Pisani, A	1
Jane, DE; Pittaway, K; Sunter, DC; Thomas, NK; Watkins, JC	1
Cao, CQ; Evans, RH; Headley, PM; Udvarhelyi, PM	1
Maiese, K; Swiriduk, M; TenBroeke, M	1
Neuman, RS; Rahman, S	1
Schoepp, DD; Wright, RA	1
Kamiya, H; Sawada, S; Yamamoto, C; Yoshino, M	1
Bedingfield, JS; Jane, DE; Kemp, MC; Roberts, PJ; Tse, HW; Watkins, JC	1
Bushell, TJ; Collingridge, GL; Garthwaite, J; Jane, DE; Tse, HW; Watkins, JC	1
Bernardi, G; Spadoni, F; Stefani, A	1
Kaneko, A; Sasaki, T	1
Nakamura, Y; Ogata, T; Schubert, P	1
Arnolda, LF; Chalmers, JP; Llewellyn-Smith, IJ; Minson, JB; Pilowsky, PM	1
Iwata, Y; Kittaka, H; Mori, N; Niwa, S; Osonoe, K; Suzuki, K; Yamada, Y	1
el Manira, A; Grillner, S; Krieger, P	1
Herrero, I; Miras-Portugal, MT; Sánchez-Prieto, J; Vázquez, E	1
Jane, DE; Thomas, NK; Tse, HW; Watkins, JC	1
Coderre, TJ; Fisher, K	1
Bernardi, G; Calabresi, P; Centonze, D; Pisani, A	1
Dubé, GR; Marshall, KC	2
Keirstead, SA; Miller, RF	1
Beck, H; Clusmann, H; Dietrich, D; Elger, CE; Kral, T; Schramm, J	1
Cassidy, EM; O'Connor, JJ; O'Leary, DM	1
Shen, W; Slaughter, MM	1
Daw, NW; Jin, X	1
Fu, XW; Wu, SH	1
Davidoff, RA; Hackman, JC; Holohean, AM	1
Connaughton, VP; Nelson, R	1
Hasser, EM; Hay, M; Hoang, CJ; Price, EM	1
Akaike, N; Katsurabayashi, S; Kubota, H; Rhee, JS; Wang, ZM	1
Morsette, DJ; Sidorowicz, H; Sladek, CD	1
Chappell, RL; Rosenstein, FJ	1
Allgeier, H; Knöpfel, T; Kuhn, R	1
Kinzie, JM; Saugstad, JA; Segerson, TP; Shinohara, MM; Westbrook, GL	1
Laurie, DJ; Schoeffter, P; Sommer, B; Wiederhold, KH	1
Arnold, JS; Belagaje, RM; Burgett, SG; Johnson, BG; Rockey, PK; Rosteck, PR; Schoepp, DD; Wright, RA; Wu, S	1
Amori, L; Costantino, G; Flor, PJ; Gasparini, F; Kuhn, R; Marinozzi, M; Pellicciari, R; Vranesic, I	1
Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO	1
Arnold, MB; Ornstein, PL; Schoepp, DD; Wheeler, WJ; Wright, RA	1
Acher, F; Bertrand, HO; Brabet, I; Pin, JP; Triballeau, N	1

Reviews

2 review(s) available for 1-amino-1,3-dicarboxycyclopentane and 2-amino-4-phosphonobutyric acid

Article	Year
Metabotropic glutamate receptors: novel targets for drug development. Journal of medicinal chemistry, 1995, Apr-28, Volume: 38, Issue:9 Topics: Animals; Cloning, Molecular; Drug Design; Humans; Receptors, Metabotropic Glutamate	1995
Ligands for glutamate receptors: design and therapeutic prospects. Journal of medicinal chemistry, 2000, Jul-13, Volume: 43, Issue:14 Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses	2000

Other Studies

68 other study(ies) available for 1-amino-1,3-dicarboxycyclopentane and 2-amino-4-phosphonobutyric acid

Article	Year
Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist. Journal of medicinal chemistry, 1998, May-07, Volume: 41, Issue:10 Topics: Animals; Bridged Bicyclo Compounds; Calcium; Cells, Cultured; Cerebellum; CHO Cells; Cricetinae; Cyclic AMP; Cycloleucine; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Glutamic Acid; Inositol Phosphates; Kidney; Ligands; Models, Molecular; Molecular Conformation; Norbornanes; Rats; Receptors, Metabotropic Glutamate; Stereoisomerism	1998
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Metabotropic glutamate receptors are required for the induction of long-term potentiation. Neuron, 1992, Volume: 9, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Alanine; Aminobutyrates; Animals; Calcium; Cycloleucine; Dose-Response Relationship, Drug; Egtazic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Male; Microinjections; Neurons; Organ Culture Techniques; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Time Factors	1992
Trans-ACPD and L-APB presynaptically inhibit excitatory glutamatergic transmission in the basolateral amygdala (BLA). Neuroscience letters, 1992, May-11, Volume: 139, Issue:1 Topics: Aminobutyrates; Amygdala; Animals; Cycloleucine; Electrodes; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley; Synaptic Transmission	1992
Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus. The Journal of physiology, 1991, Volume: 444 Topics: Aminobutyrates; Animals; Cycloleucine; Electrophysiology; Hippocampus; In Vitro Techniques; Neurotoxins; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission	1991
Agonists selective for phosphoinositide-coupled receptors sensitize neurons to depolarization by L-2-amino-4-phosphonobutanoic acid (L-AP4). Brain research, 1991, Aug-02, Volume: 555, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Carbachol; Cerebral Cortex; Cycloleucine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Neuromuscular Depolarizing Agents; Neurons; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear	1991
Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor. European journal of pharmacology, 1989, Aug-03, Volume: 166, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cycloleucine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface	1989
Characterization of an extended glutamate receptor of the on bipolar neuron in the vertebrate retina. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:1 Topics: Aminobutyrates; Animals; Cycloleucine; Electrophysiology; Glutamates; Ibotenic Acid; Light; Molecular Conformation; Necturus maculosus; Neurons; Phosphoserine; Photoreceptor Cells; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Structure-Activity Relationship	1985
Receptor subtypes linked to metabotropic glutamate receptor agonist-mediated limbic seizures in mice. Annals of the New York Academy of Sciences, 1995, Sep-15, Volume: 765 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Cycloleucine; Dose-Response Relationship, Drug; Functional Laterality; Limbic System; Male; Mice; Mice, Inbred Strains; Microinjections; Models, Neurological; Neurotoxins; Phosphoserine; Receptors, Metabotropic Glutamate; Seizures; Stereoisomerism	1995
Membrane currents evoked by excitatory amino acid agonists in ON bipolar cells of the mudpuppy retina. Journal of neurophysiology, 1993, Volume: 70, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Cadmium; Cell Membrane; Cobalt; Cycloleucine; Electrophysiology; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Necturus maculosus; Neurotransmitter Agents; Receptors, Amino Acid; Retina	1993
The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina. Neuroscience, 1994, Volume: 59, Issue:4 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cycloleucine; Dextromethorphan; Eye Proteins; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Intraocular Pressure; Ischemia; Kainic Acid; Kynurenic Acid; Memantine; N-Methylaspartate; Oxygen; Potassium Cyanide; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Vessels; Serotonin	1994
Competitive antagonism by phenylglycine derivatives at type I metabotropic glutamate receptors. Molecular and cellular neurosciences, 1994, Volume: 5, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Benzoates; Binding, Competitive; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cycloleucine; Cytidine Diphosphate Diglycerides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; Neurons; Neurotoxins; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Signal Transduction	1994
Inhibition of endogenous dopamine release in amphibian retina by L-2-amino-4-phosphonobutyric acid (L-AP4) and trans-2-aminocyclopentane-1,3-dicarboxylate (ACPD). Brain research, 1994, Jun-27, Volume: 649, Issue:1-2 Topics: Aminobutyrates; Animals; Cycloleucine; Dopamine; Ion Channels; Light; Neurotoxins; Picrotoxin; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Stereoisomerism; Xenopus laevis	1994
Glutamate-induced swelling of single astroglial cells in primary culture. Neuroscience, 1994, Volume: 63, Issue:4 Topics: Aminobutyrates; Animals; Animals, Newborn; Astrocytes; Calcium; Cell Size; Cells, Cultured; Cerebral Cortex; Cycloleucine; Extracellular Space; Glutamic Acid; GTP-Binding Proteins; Ion Channels; Neurotoxins; Pertussis Toxin; Potassium Channels; Rats; Receptors, Glutamate; Spectrometry, Fluorescence; Virulence Factors, Bordetella	1994
Metabotropic glutamate receptor agonists inhibit endogenous glutamate release from rat striatal synaptosomes. European journal of pharmacology, 1995, Apr-13, Volume: 277, Issue:1 Topics: 4-Aminopyridine; Aminobutyrates; Animals; Corpus Striatum; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Rats; Receptors, Metabotropic Glutamate; Synaptosomes	1995
Effects of bromohomoibotenate on metabotropic glutamate receptors. Neuroreport, 1994, Dec-20, Volume: 5, Issue:18 Topics: Aminobutyrates; Animals; Binding, Competitive; Cell Line; Cerebral Cortex; Cricetinae; Cyclic AMP; Cycloleucine; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Kidney; Membranes; Phosphatidylinositols; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Stereoisomerism	1994
Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide. Molecular pharmacology, 1995, Volume: 47, Issue:5 Topics: Aminobutyrates; Amyloid beta-Peptides; Animals; Apoptosis; Benzoates; Calcium Channels; Cells, Cultured; Cerebellum; Cycloleucine; Glycine; Mice; Nerve Degeneration; Neurons; Peptide Fragments; Phosphoserine; Receptors, Metabotropic Glutamate	1995
Changes of pharmacological properties of (1S,3R)-ACPD-sensitive glutamate binding sites in developing mouse cerebellum. Neurochemistry international, 1994, Volume: 25, Issue:3 Topics: Aminobutyrates; Animals; Autoradiography; Cerebellum; Cycloleucine; Kinetics; Mice; Receptors, Metabotropic Glutamate	1994
Potentiating and depressant effects of metabotropic glutamate receptor agonists on high-voltage-activated calcium currents in cultured retinal ganglion neurons from postnatal mice. Pflugers Archiv : European journal of physiology, 1994, Volume: 426, Issue:1-2 Topics: Alanine; Aminobutyrates; Animals; Calcium; Calcium Channels; Cells, Cultured; Cycloleucine; Glutamates; Glutamic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intracellular Fluid; Mice; omega-Conotoxin GVIA; Organophosphorus Compounds; Peptides; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retinal Ganglion Cells	1994
Actions of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) in retinal ON bipolar cells indicate that it is an agonist at L-AP4 receptors. The Journal of general physiology, 1994, Volume: 103, Issue:6 Topics: Aminobutyrates; Animals; Cycloleucine; Excitatory Amino Acid Agonists; GABA-A Receptor Agonists; Glycine; Necturus maculosus; Receptors, GABA-A; Receptors, Glutamate; Retina	1994
Pharmacological similarity between the retinal APB receptor and the family of metabotropic glutamate receptors. Journal of neurophysiology, 1994, Volume: 71, Issue:6 Topics: Ambystoma; Aminobutyrates; Animals; Culture Techniques; Cycloleucine; Necturus; Neurotoxins; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Retina; Synaptic Transmission	1994
Metabotropic glutamate receptor activation decreases epileptiform activity in rat neocortex. Neuroscience letters, 1994, Jun-06, Volume: 174, Issue:1 Topics: Aminobutyrates; Animals; Bicuculline; Cerebral Cortex; Cycloleucine; Epilepsy; Evoked Potentials; Female; GABA-A Receptor Antagonists; In Vitro Techniques; Male; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate	1994
Cortical layer-specific effects of the metabotropic glutamate receptor agonist 1S,3R-ACPD in rat primary somatosensory cortex in vivo. The European journal of neuroscience, 1994, Sep-01, Volume: 6, Issue:9 Topics: Aminobutyrates; Animals; Benzoates; Cycloleucine; Glycine; Iontophoresis; Male; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Somatosensory Cortex; Synapses	1994
Modulation of cyclic AMP formation by putative metabotropic receptor agonists. British journal of pharmacology, 1994, Volume: 111, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Guinea Pigs; Hydrolysis; In Vitro Techniques; Phosphatidylinositols; Receptors, Metabotropic Glutamate	1994
Presynaptic depression of synaptic transmission mediated by activation of metabotropic glutamate receptors in rat neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:8 Topics: Aminobutyrates; Animals; Benzoates; Cycloleucine; Electrophysiology; Female; Frontal Lobe; Glycine; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Presynaptic; Synaptic Transmission	1994
Inhibitors of metabotropic glutamate receptors produce amnestic effects in chicks. Neuroreport, 1994, May-09, Volume: 5, Issue:9 Topics: Aminobutyrates; Amnesia; Animals; Avoidance Learning; Benzoates; Chickens; Cycloleucine; Cyclopropanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Male; Motor Activity; Phosphoserine; Receptors, Metabotropic Glutamate	1994
L-2-amino-4-phosphonobutanoic acid and 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid reduce paired-pulse depression recorded from medial perforant path in the dentate gyrus of rat hippocampal slices. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:1 Topics: Aminobutyrates; Animals; Atropine; Baclofen; Carbachol; Cycloleucine; Depression, Chemical; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neural Pathways; Neurotransmitter Uptake Inhibitors; Picrotoxin; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Theophylline	1993
Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors. European journal of pharmacology, 1994, Jan-15, Volume: 266, Issue:2 Topics: Aminobutyrates; Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Electrophysiology; Glycine; Guinea Pigs; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission	1994
The effects of the metabotropic glutamate receptor agonist 1S,3R-ACPD on neurones in the rat primary somatosensory cortex in vivo. Neuropharmacology, 1994, Volume: 33, Issue:1 Topics: Action Potentials; Aminobutyrates; Animals; Cycloleucine; Extracellular Space; Iontophoresis; Male; Neurons; Neurotoxins; Physical Stimulation; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex	1994
Heterogeneity of metabotropic glutamate receptors in the striatum: electrophysiological evidence. The European journal of neuroscience, 1993, Oct-01, Volume: 5, Issue:10 Topics: Alanine; Aminobutyrates; Animals; Cerebral Cortex; Corpus Striatum; Cycloleucine; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Lithium Chloride; Neuronal Plasticity; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, Glutamate; Stereoisomerism; Synapses	1993
New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Neuropharmacology, 1995, Volume: 34, Issue:8 Topics: Aminobutyrates; Animals; Animals, Newborn; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Motor Neurons; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Spinal Cord; Tetrodotoxin	1995
A comparison of the effects of selective metabotropic glutamate receptor agonists on synaptically evoked whole cell currents of rat spinal ventral horn neurones in vitro. British journal of pharmacology, 1995, Volume: 115, Issue:8 Topics: Aminobutyrates; Animals; Anterior Horn Cells; Cycloleucine; Depression, Chemical; Excitatory Amino Acid Agonists; N-Methylaspartate; Neurons; Neurotoxins; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission	1995
Cellular mechanisms of protection by metabotropic glutamate receptors during anoxia and nitric oxide toxicity. Journal of neurochemistry, 1996, Volume: 66, Issue:6 Topics: Alanine; Aminobutyrates; Animals; Brain Ischemia; Cell Death; Cell Hypoxia; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction	1996
Characterization of metabotropic glutamate receptor-mediated facilitation of N-methyl-D-aspartate depolarization of neocortical neurones. British journal of pharmacology, 1996, Volume: 117, Issue:4 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine; Alkaloids; Aminobutyrates; Animals; Cerebral Cortex; Cyclic GMP; Cycloleucine; Male; Neurons; Phorbol Esters; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Staurosporine	1996
Differentiation of group 2 and group 3 metabotropic glutamate receptor cAMP responses in the rat hippocampus. European journal of pharmacology, 1996, Feb-22, Volume: 297, Issue:3 Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Colforsin; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Vasoactive Intestinal Peptide	1996
A metabotropic glutamate receptor agonist DCG-IV suppresses synaptic transmission at mossy fiber pathway of the guinea pig hippocampus. Neuroscience letters, 1996, Mar-22, Volume: 207, Issue:1 Topics: Aminobutyrates; Animals; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Receptors, Metabotropic Glutamate	1996
Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs). British journal of pharmacology, 1995, Volume: 116, Issue:8 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Glycine; Inositol Phosphates; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Structure-Activity Relationship	1995
Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices. British journal of pharmacology, 1996, Volume: 117, Issue:7 Topics: 2-Chloroadenosine; Alanine; Aminobutyrates; Animals; Animals, Newborn; Cycloleucine; Depression, Chemical; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Organophosphonates; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrazoles	1996
L-AP4 inhibits high voltage-activated Ca2+ currents in pyramidal cortical neurones. Neuroreport, 1996, Jan-31, Volume: 7, Issue:2 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Barium; Calcium Channel Blockers; Cerebral Cortex; Cycloleucine; Excitatory Amino Acid Agonists; Ion Channel Gating; Male; Microtubule-Associated Proteins; Neurotoxins; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate	1996
L-Glutamate-induced responses in OFF-type bipolar cells of the cat retina. Vision research, 1996, Volume: 36, Issue:6 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Calcium; Cats; Chlorides; Cycloleucine; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; In Vitro Techniques; Ion Transport; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium; Retina; Retinal Cone Photoreceptor Cells; Sodium	1996
Potentiated cAMP rise in metabotropically stimulated rat cultured astrocytes by a Ca2+-related A1/A2 adenosine receptor cooperation. The European journal of neuroscience, 1996, Volume: 8, Issue:6 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Astrocytes; Calcium; Cells, Cultured; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Agonists; Purinergic P1 Receptor Agonists; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stimulation, Chemical	1996
Tachycardia after glutamate injection in rat spinal cord is not blocked by kynurenate or mimicked by metabotropic agonists. Clinical and experimental pharmacology & physiology, 1996, Volume: 23, Issue:9 Topics: Aminobutyrates; Analysis of Variance; Animals; Blood Pressure; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Injections, Spinal; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Rats; Rats, Inbred WKY; Receptors, Metabotropic Glutamate; Spinal Cord; Tachycardia	1996
Anticonvulsant action of metabotropic glutamate receptor agonists in kindled amygdala of rats. Neuroscience letters, 1996, Feb-02, Volume: 204, Issue:1-2 Topics: Aminobutyrates; Amygdala; Animals; Anticonvulsants; Cycloleucine; Electroencephalography; Excitatory Amino Acid Agonists; Injections; Kindling, Neurologic; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate	1996
Activation of pharmacologically distinct metabotropic glutamate receptors depresses reticulospinal-evoked monosynaptic EPSPs in the lamprey spinal cord. Journal of neurophysiology, 1996, Volume: 76, Issue:6 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Axons; Benzoates; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Lampreys; Neural Pathways; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Reticular Formation; Spinal Cord; Synaptic Transmission	1996
Decrease in [Ca2+]c but not in cAMP Mediates L-AP4 inhibition of glutamate release: PKC-mediated suppression of this inhibitory pathway. The European journal of neuroscience, 1996, Volume: 8, Issue:4 Topics: Aminobutyrates; Animals; Calcium; Cerebral Cortex; Cyclic AMP; Cycloleucine; Cytoplasm; Excitatory Amino Acid Antagonists; Osmolar Concentration; Protein Kinase C; Rats; Rats, Wistar	1996
Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord. Neuropharmacology, 1996, Volume: 35, Issue:8 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Animals, Newborn; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamates; Glycine; N-Methylaspartate; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Spinal Cord	1996
The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception. Pain, 1996, Volume: 68, Issue:2-3 Topics: Aminobutyrates; Analysis of Variance; Animals; Benzoates; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Male; Pain; Rats; Receptors, Metabotropic Glutamate; Resorcinols	1996
Activation of group III metabotropic glutamate receptors depresses glutamatergic transmission at corticostriatal synapse. Neuropharmacology, 1997, Volume: 36, Issue:6 Topics: Aminobutyrates; Animals; Benzoates; Corpus Striatum; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Neural Inhibition; Neuroprotective Agents; Phosphoserine; Presynaptic Terminals; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission	1997
Modulation of excitatory synaptic transmission in locus coeruleus by multiple presynaptic metabotropic glutamate receptors. Neuroscience, 1997, Volume: 80, Issue:2 Topics: Aminobutyrates; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acids; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Neurotoxins; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission	1997
Metabotropic glutamate receptor agonists evoke calcium waves in isolated Müller cells. Glia, 1997, Volume: 21, Issue:2 Topics: Adenosine Triphosphate; Ambystoma; Aminobutyrates; Animals; Calcium Channels; Cycloleucine; Excitatory Amino Acid Agonists; Fluorescent Dyes; Histocytochemistry; In Vitro Techniques; Neuroglia; Neuroprotective Agents; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina	1997
Metabotropic glutamate receptors modulate synaptic transmission in the perforant path: pharmacology and localization of two distinct receptors. Brain research, 1997, Sep-05, Volume: 767, Issue:2 Topics: Aminobutyrates; Animals; Cycloleucine; Dentate Gyrus; Excitatory Postsynaptic Potentials; Male; Neuronal Plasticity; Perforant Pathway; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission	1997
Group II and III metabotropic glutamate receptors modulate paired pulse depression in the rat dentate gyrus in vitro. European journal of pharmacology, 1997, Dec-04, Volume: 340, Issue:1 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Cycloleucine; Cyclopropanes; Dentate Gyrus; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Resorcinols	1997
Metabotropic and ionotropic glutamate receptors regulate calcium channel currents in salamander retinal ganglion cells. The Journal of physiology, 1998, Aug-01, Volume: 510 ( Pt 3) Topics: Ambystoma; Aminobutyrates; Animals; Barium; Calcium Channels; Chelating Agents; Cycloleucine; Egtazic Acid; Excitatory Amino Acid Agonists; In Vitro Techniques; Kainic Acid; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Retinal Ganglion Cells; Signal Transduction	1998
The group III metabotropic glutamate receptor agonist, l-AP4, reduces EPSPs in some layers of rat visual cortex. Brain research, 1998, Jun-29, Volume: 797, Issue:2 Topics: Alanine; Aminobutyrates; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; N-Methylaspartate; Neuroprotective Agents; Presynaptic Terminals; Rats; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Visual Cortex	1998
Glutamate receptors underlying excitatory synaptic transmission in the rat's lateral superior olive studied in vitro. Hearing research, 1998, Volume: 122, Issue:1-2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aminobutyrates; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Neuroprotective Agents; Olivary Nucleus; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	1998
Mechanisms involved in the metabotropic glutamate receptor-enhancement of NMDA-mediated motoneurone responses in frog spinal cord. British journal of pharmacology, 1999, Volume: 126, Issue:1 Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chlorpromazine; Cycloleucine; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; GTP-Binding Proteins; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Pertussis Toxin; Rana pipiens; Receptors, Metabotropic Glutamate; Reflex; Resorcinols; Second Messenger Systems; Spinal Cord; Sulfonamides; Tetrodotoxin; Thapsigargin; Virulence Factors, Bordetella	1999
Activity-dependent activation of presynaptic metabotropic glutamate receptors in locus coeruleus. Journal of neurophysiology, 2000, Volume: 83, Issue:3 Topics: Aminobutyrates; Animals; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Feedback; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Locus Coeruleus; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Receptors, Presynaptic	2000
Axonal stratification patterns and glutamate-gated conductance mechanisms in zebrafish retinal bipolar cells. The Journal of physiology, 2000, Apr-01, Volume: 524 Pt 1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Axons; Chlorides; Cycloleucine; Dendrites; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kainic Acid; Neurons; Picrotoxin; Retina; Strychnine; Zebrafish	2000
Activation of metabotropic glutamate receptors inhibits synapsin I phosphorylation in visceral sensory neurons. The Journal of membrane biology, 2000, Dec-01, Volume: 178, Issue:3 Topics: Aminobutyrates; Animals; Cycloleucine; Exocytosis; Gene Expression Regulation; Membrane Potentials; Nerve Tissue Proteins; Neurons, Afferent; Nodose Ganglion; Patch-Clamp Techniques; Phosphorylation; Potassium Chloride; Protein Isoforms; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Synapsins	2000
cAMP-dependent presynaptic regulation of spontaneous glycinergic IPSCs in mechanically dissociated rat spinal cord neurons. Journal of neurophysiology, 2001, Volume: 85, Issue:1 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Barium; Cadmium; Calcium; Colforsin; Cyclic AMP; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Agonists; In Vitro Techniques; Neural Inhibition; Neurons; Patch-Clamp Techniques; Potassium; Presynaptic Terminals; Propionates; Rats; Rats, Wistar; Receptors, Glycine; Receptors, Metabotropic Glutamate; Spinal Cord	2001
Role of metabotropic glutamate receptors in vasopressin and oxytocin release. American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:2 Topics: Aminobutyrates; Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hypothalamo-Hypophyseal System; In Vitro Techniques; Indans; Male; Neurons; Neuroprotective Agents; Osmolar Concentration; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Vasopressins	2001
Endogenous zinc as a retinal neuromodulator: evidence from the skate (Raja erinacea). Neuroscience letters, 2003, Jul-17, Volume: 345, Issue:2 Topics: Aminobutyrates; Animals; Cells, Cultured; Cycloleucine; Dose-Response Relationship, Drug; Drug Interactions; Electroretinography; Excitatory Amino Acid Agonists; GABA Antagonists; Histidine; Kainic Acid; Membrane Potentials; Neuroprotective Agents; Patch-Clamp Techniques; Picrotoxin; Retina; Skates, Fish; Zinc	2003
Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile. Molecular pharmacology, 1997, Volume: 51, Issue:1 Topics: Amino Acid Sequence; Animals; DNA, Complementary; Excitatory Amino Acid Agonists; Female; GTP-Binding Proteins; Mice; Molecular Sequence Data; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; RNA, Messenger; Xenopus laevis	1997
Cloning, distribution and functional expression of the human mGlu6 metabotropic glutamate receptor. Neuropharmacology, 1997, Volume: 36, Issue:2 Topics: Amino Acid Sequence; Animals; Cell Line; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; DNA; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Receptors, Metabotropic Glutamate; Retina; RNA, Messenger; Tissue Distribution	1997
Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells. Brain research. Molecular brain research, 1998, Volume: 53, Issue:1-2 Topics: Amino Acid Sequence; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Cell Line; Cloning, Molecular; Colforsin; Consensus Sequence; Cyclic AMP; DNA, Complementary; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Mice; Molecular Sequence Data; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transfection	1998
Synthesis, molecular modeling and preliminary biological evaluation of 1-amino-3-phosphono-3-cyclopentene-1-carboxylic acid and 1-amino-3-phosphono-2-cyclopentene-1-carboxylic acid, two novel agonists of metabotropic glutamate receptors of group III. Bioorganic & medicinal chemistry letters, 2000, Jul-03, Volume: 10, Issue:13 Topics: Animals; Biological Assay; CHO Cells; Colforsin; Cricetinae; Cyclopentanes; Excitatory Amino Acid Agonists; Humans; Molecular Structure; Receptors, Metabotropic Glutamate	2000
Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl) glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:6 Topics: Amino Acids; Binding, Competitive; Cell Membrane; Excitatory Amino Acid Antagonists; Humans; Kinetics; Radioligand Assay; Receptors, Metabotropic Glutamate; Recombinant Proteins; Substrate Specificity; Tritium; Xanthenes	2000
Virtual screening workflow development guided by the "receiver operating characteristic" curve approach. Application to high-throughput docking on metabotropic glutamate receptor subtype 4. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Binding Sites; Databases, Factual; Drug Design; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, Metabotropic Glutamate; ROC Curve	2005