Compounds > 1,9-dideoxyforskolin
Page last updated: 2024-09-02

1,9-dideoxyforskolin and verapamil

1,9-dideoxyforskolin has been researched along with verapamil in 7 studies

Compound Research Comparison

Studies
(1,9-dideoxyforskolin)		Trials
(1,9-dideoxyforskolin)		Recent Studies (post-2010)
(1,9-dideoxyforskolin)		Studies
(verapamil)		Trials
(verapamil)		Recent Studies (post-2010) (verapamil)
1110217,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomy1,9-dideoxyforskolin (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirst, BH; Hunter, J; Simmons, NL2
Díaz, M; Higgins, CF; Rucăreanu, C; Sepúlveda, FV; Valverde, MA1
Gill, DR; Higgins, CF; Hyde, SC; McNaughton, PA; Mintenig, GM; Sardini, A; Sepúlveda, FV; Valverde, MA1
Alton, EW; Geddes, DM; Munkonge, FM; Osborne, LR1
Chou, CY; Shen, MR; Wu, SN1
Krouse, ME; Law, TC; Luckie, DB; Sikic, BI; Wine, JJ1

Other Studies

7 other study(ies) available for 1,9-dideoxyforskolin and verapamil

ArticleYear
Transepithelial vinblastine secretion mediated by P-glycoprotein is inhibited by forskolin derivatives.
    Biochemical and biophysical research communications, 1991, Dec-16, Volume: 181, Issue:2

    Topics: Adenylyl Cyclases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Colforsin; Dogs; Epithelium; Kidney; Membrane Glycoproteins; Verapamil; Vinblastine

1991
Volume-activated chloride channels in HeLa cells are blocked by verapamil and dideoxyforskolin.
    Pflugers Archiv : European journal of physiology, 1993, Volume: 422, Issue:4

    Topics: Adenosine Triphosphate; Chloride Channels; Chlorides; Colforsin; HeLa Cells; Humans; Hypotonic Solutions; Ion Channels; Membrane Potentials; Membrane Proteins; Osmosis; Verapamil

1993
Drug efflux mediated by the human multidrug resistance P-glycoprotein is inhibited by cell swelling.
    Journal of cell science, 1994, Volume: 107 ( Pt 12)

    Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Compartmentation; Cell Membrane Permeability; Chloride Channels; Colforsin; Doxorubicin; Drug Resistance, Multiple; Humans; Mice; Microscopy, Confocal; Osmotic Pressure; Recombinant Proteins; Verapamil

1994
Lack of inhibition by dideoxy-forskolin and verapamil of DIDS-sensitive volume-activated Cl- secretion in human squamous lung carcinoma epithelial cells.
    Biochimica et biophysica acta, 1994, Dec-30, Volume: 1224, Issue:3

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Blotting, Western; Carcinoma, Squamous Cell; Cell Size; Chlorides; Colforsin; Humans; Lung Neoplasms; Osmolar Concentration; Tumor Cells, Cultured; Verapamil

1994
Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers.
    Pharmaceutical research, 1993, Volume: 10, Issue:5

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Colforsin; Docetaxel; Epithelium; Humans; Intestinal Absorption; Intestinal Mucosa; Membrane Glycoproteins; Nifedipine; Paclitaxel; Taxoids; Tumor Cells, Cultured; Verapamil; Vinblastine

1993
Volume-sensitive chloride channels associated with human cervical carcinogenesis.
    Cancer research, 1995, Dec-15, Volume: 55, Issue:24

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Carcinoma in Situ; Carcinoma, Squamous Cell; Cell Transformation, Viral; Cervix Uteri; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; DNA Primers; DNA, Viral; Epithelium; Female; Humans; Ion Channel Gating; Molecular Sequence Data; Papillomaviridae; Tumor Cells, Cultured; Uterine Cervical Neoplasms; Verapamil; Water-Electrolyte Balance

1995
Doxorubicin selection for MDR1/P-glycoprotein reduces swelling-activated K+ and Cl- currents in MES-SA cells.
    The American journal of physiology, 1996, Volume: 270, Issue:4 Pt 1

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Fluids; Chlorides; Colforsin; Doxorubicin; Drug Resistance, Multiple; Electric Conductivity; Female; Humans; Patch-Clamp Techniques; Potassium; RNA, Messenger; Stilbenes; Tumor Cells, Cultured; Verapamil

1996