1,9-dideoxyforskolin has been researched along with colforsin in 109 studies
| Studies (1,9-dideoxyforskolin) | Trials (1,9-dideoxyforskolin) | Recent Studies (post-2010) (1,9-dideoxyforskolin) | Studies (colforsin) | Trials (colforsin) | Recent Studies (post-2010) (colforsin) |
|---|---|---|---|---|---|
| 111 | 0 | 2 | 13,460 | 46 | 1,298 |
| Protein | Taxonomy | 1,9-dideoxyforskolin (IC50) | colforsin (IC50) |
|---|---|---|---|
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | 1.729 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.041 | |
| Adenylate cyclase type 1 | Homo sapiens (human) | 0.0955 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (8.26) | 18.7374 |
| 1990's | 81 (74.31) | 18.2507 |
| 2000's | 16 (14.68) | 29.6817 |
| 2010's | 3 (2.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, A; Karaki, H | 1 |
| Felíu, JE; Herias, M; Olea, J; Pereda, C; Rossi, I | 1 |
| Gauthier, C; Soustre, H | 1 |
| Bringhurst, FR; Fukayama, S; Tashjian, AH | 1 |
| Ganetzky, B; Stern, M | 1 |
| Hirst, BH; Hunter, J; McEwan, GT; Simmons, NL | 1 |
| Olianas, MC; Onali, P | 1 |
| Díaz, M; Gill, DR; Higgins, CF; Hyde, SC; Sepúlveda, FV; Valverde, MA | 1 |
| Ishac, E; Li, C; White, G | 1 |
| De Luca, M; Galietta, LJ; Mastrocola, T; Romeo, G; Rugolo, M | 1 |
| Appel, NM; De Souza, EB; Laurenza, A; Robbins, JD; Seamon, KB; Simpson, IA | 1 |
| Chan, JY; Chan, SH; Fu, MJ; Lin, KS | 1 |
| Corrèze, C; Delemer, B; Dib, K; Haye, B; Jacquemin, C; Saunier, B | 1 |
| Farkas, EM; Papachristou, DN; Patel, YC; Zingg, HH | 1 |
| Morris, DI; Ruoho, AE; Seamon, KB; Speicher, LA; Tew, KD | 1 |
| Hirst, BH; Hunter, J; Simmons, NL | 2 |
| Wadler, S; Yang, CP | 1 |
| Doi, K; Matsunaga, T; Mori, N | 1 |
| Boutjdir, M; Fischmeister, R; Hanf, R; Méry, PF; Shrier, A | 1 |
| Aronstam, RS; Daly, JW; Nishizawa, Y; Seamon, KB | 1 |
| Baidan, LV; Fertel, RH; Wood, JD; Xia, Y | 1 |
| Anderson, RJ; Breckon, R; Colston, D | 1 |
| Crooks, JR; Keogh, DP; Mitchell, MJ; Smith, SL | 1 |
| Elders, MJ; Hu, LM; Kemp, SF; Peng, CF; Smith, WG | 1 |
| McMorris, FA; Raible, DW | 1 |
| Bonvallet, R; Lemtiri-Chlieh, F; Rougier, O | 1 |
| Baxter, DA; Byrne, JH | 1 |
| Sitkovsky, MV; Takayama, H; Trenn, G | 1 |
| Aldrich, RW; Garber, SS; Hoshi, T | 1 |
| White, MM | 1 |
| Harris-Warrick, RM | 1 |
| Wickelgren, WO; Womble, MD | 1 |
| Wadler, S; Wiernik, PH | 1 |
| Adams, M; Boarder, MR; Marriott, D | 1 |
| McGee, R; McHugh, EM | 1 |
| Habberfield, AD; Joost, HG; Laurenza, A; Seamon, KB; Simpson, IA | 1 |
| Alexander, SP; Hernández, F; Kendall, DA | 1 |
| Fan, P | 1 |
| Kuzhikandathil, EV; Molloy, GR | 1 |
| Eltze, M | 1 |
| Ambrosio, C; Barbaccia, ML; Massotti, M; Roscetti, G; Trabucchi, M | 1 |
| Craig, CG; Temple, SD; White, TD | 1 |
| Bellé, R; Cormier, P; Drewing, S; Minella, O; Mulner-Lorillon, O; Poulhe, R; Schmalzing, G | 1 |
| Alvaro, D; Boyer, JL; Cho, W; Mennone, A | 1 |
| Furukata, K; Hosokami, T; Ide, S; Iimori, T; Ikegami, S; Sasaki, T; Senda, M | 1 |
| Reich, H; Sei, Y | 1 |
| Gean, PW; Huang, CC | 1 |
| Díaz, M; Higgins, CF; Rucăreanu, C; Sepúlveda, FV; Valverde, MA | 1 |
| Sorota, S | 1 |
| Gill, DR; Higgins, CF; Hyde, SC; McNaughton, PA; Mintenig, GM; Sardini, A; Sepúlveda, FV; Valverde, MA | 1 |
| Cook, SA; Lichtman, AH; Martin, BR; Welch, SP | 1 |
| Alton, EW; Geddes, DM; Munkonge, FM; Osborne, LR | 1 |
| Basile, A; Gusovsky, F; Sei, Y; Skolnick, P; Takemura, M | 1 |
| De Greef, C; Droogmans, G; Eggermont, J; Nilius, B; Raeymaekers, L; Sehrer, J; Viana, F | 1 |
| Feltz, A; Zerr, P | 1 |
| Roberts, PJ; Toms, NJ | 1 |
| Björnsson, OG; Gibbons, GF; Sparks, CE; Sparks, JD | 1 |
| Barajas-López, C | 1 |
| Kirk, J; Kirk, K | 1 |
| Katz, S; Mok, W; Phaneuf, S; Salari, H; Wong, S | 1 |
| Dover, PJ; McCaig, CD | 1 |
| Chou, CY; Shen, MR; Wu, SN | 1 |
| Kim, KT; Park, TJ | 1 |
| Argent, BE; Chambers, JA; Gray, MA; Harris, A; Mathews, CJ; Verdon, B; Wardle, CJ; Winpenny, JP | 1 |
| Chiu, CT; Fan, LW; Tsao, HL; Yang, C; Yu, SM | 1 |
| Becherer, U; Feltz, A; Rodeau, JL; Zerr, P | 1 |
| Hewlett, EL; Login, IS | 1 |
| Asai, T; McDonald, TF; Pelzer, S | 1 |
| Krouse, ME; Law, TC; Luckie, DB; Sikic, BI; Wine, JJ | 1 |
| Tokimasa, T | 1 |
| Buczko, E; Dufau, ML; Khanum, A | 1 |
| Galietta, LJ; Romano, L; Rossi, GA; Sacco, O; Zegarra-Moran, O | 1 |
| Cikós, T; Kalthoff, H; Krull, NB; Ungefroren, H | 1 |
| Bucher, B; Côrtes, SF; Lemos, VS; Takeda, K | 1 |
| Gandía, L; García, AG; Ramirez-Lavergne, C; Trifaró, JM; Villarroya, M; Vitale, ML | 1 |
| Miranda, D; Morán, J; Pasantes-Morales, H; Sánchez Olea, R | 1 |
| Miranda, D; Morán, J; Pasantes-Morales, H; Peña-Segura, C | 1 |
| Chen, Y; Herness, MS; Sun, XD | 1 |
| Bhatnagar, A; Dhir, P; Srivastava, SK; Wang, LF | 1 |
| Chang, YH; Chern, Y; Ching, YH; Conti, M; Lai, HL; Lee, YC | 1 |
| Cid, LP; Eguiguren, AL; Sepúlveda, FV; Stutzin, A | 1 |
| Komatsu, N; Muramatsu, T; Oda, T | 1 |
| Khan, M; Pahan, K; Singh, I | 1 |
| Ambikapathy, S; Bond, TD; Mohammad, S; Valverde, MA | 1 |
| Al-Dahan, MI; Jalilian Tehrani, MH; Thalmann, RH | 1 |
| Christofi, FL; Jamaleddin, AJ; Liu, CY; Zhang, H | 1 |
| DePinho, RA; Eisen, AM; Gallo, V; Ghiani, CA; Knutson, PL; McBain, CJ; Yuan, X | 1 |
| d'Alcantara, P; Schiffmann, SN; Swillens, S | 1 |
| Darszon, A; de la Vega-Beltrán, JL; Espinosa, F; Gasque, G; López-González, I; Serrano, CJ; Treviño, CL | 1 |
| Garfield, RE; Okawa, T; Saade, GR; Syal, AS; Vedernikov, YP | 1 |
| Morales-Mulia, M; Morán, J; Pasantes-Morales, H | 1 |
| Bottrill, FE; Hiley, CR; Omar, R; White, R | 1 |
| Brès, V; Duvoid, A; Hurbin, A; Hussy, N; Moos, FC; Orcel, H; Rabié, A | 1 |
| Lock, H; Valverde, MA | 1 |
| Evans, DI; Jones, RS; Woodhall, G | 1 |
| Liu, LA; Shi, LJ; Wang, CA | 1 |
| Hescheler, J; Lenka, N; Su, J; Ullrich, S; Yu, H | 1 |
| Anderson, AE; Mayne, A; Pfaffinger, PJ; Schrader, LA; Sweatt, JD | 1 |
| Battaglia, M; Bernardi, P; Fassetta, M; Gentile, A; Gramaglia, D; Petronilli, V; Ranzato, L; Rasola, A | 1 |
| Ding, X; Staudinger, JL | 1 |
| Di Carlo, A; Macchia, V; Mariano, A; Terracciano, D | 1 |
| Altrup, U; Ure, A | 1 |
| Asakawa, Y; Hagiwara, H; Hashimoto, T; Hoshi, T; Kudou, M; Suzuki, T; Takeuchi, F | 1 |
| Ahluwalia, J | 1 |
| Huang, XZ; Jin, D; Kim, DH; Lee, KJ; Li, JH; Qi, XF; Song, SB; Teng, YC; Yoon, YS | 1 |
| Blum, AE; Dubyak, GR; Walsh, BC | 1 |
| Campochiaro, PA; Gong, YY; Hackett, SF; Iwase, T; Lu, L; Seidel, CP; Stevens, RK; Wang, X | 1 |
| Acosta-Gómez, EI; Angel-Chavez, LI; Castro, E; Cruzblanca, H; Morales-Avalos, M | 1 |
109 other study(ies) available for 1,9-dideoxyforskolin and colforsin
| Article | Year |
|---|---|
Calcium channel blocker-like action of 1,9-dideoxyforskolin in vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Colforsin; Cytosol; Fura-2; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rats; Rats, Wistar | 1992 |
Fructose 2,6-bisphosphate levels and modulation of glycolysis by histamine, cholecystokinin, and forskolin in isolated rabbit gastric glands.
Topics: 3-O-Methylglucose; Animals; Colforsin; Cyclic AMP; Fructosediphosphates; Gastric Mucosa; Glucose; Glycolysis; Histamine; In Vitro Techniques; Kinetics; Lactates; Methylglucosides; Pepsinogens; Phosphofructokinase-2; Phosphotransferases; Rabbits; Sincalide | 1992 |
Forskolin effects on slow inward current and phasic tension of frog atrial fibres: modulation by adenosine and phosphodiesterase inhibitors.
Topics: Adenosine; Animals; Calcium Channels; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; In Vitro Techniques; Myocardial Contraction; Phosphodiesterase Inhibitors; Propranolol; Rana esculenta; Rana ridibunda; Stimulation, Chemical | 1992 |
Forskolin-induced homologous desensitization via an adenosine 3',5'-monophosphate-dependent mechanism(s) in human osteoblast-like SaOS-2 cells.
Topics: Adenylate Cyclase Toxin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Drug Combinations; Drug Tolerance; Enzyme Activation; Hormones; Humans; Osteoblasts; Parathyroid Hormone; Pertussis Toxin; Protein Kinases; Virulence Factors, Bordetella | 1992 |
Identification and characterization of inebriated, a gene affecting neuronal excitability in Drosophila.
Topics: Animals; Chromosome Mapping; Colforsin; Drosophila; Electrodes; Mutagenesis; Nerve Endings; Neurons; Phenotype; Potassium Channels; Quinidine; Synapses; Synaptic Transmission; Synaptosomes | 1992 |
Volume-activated Cl- secretion and transepithelial vinblastine secretion mediated by P-glycoprotein are not correlated in cultured human T84 intestinal epithelial layers.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Chloride Channels; Chlorides; Colforsin; Humans; Intestinal Mucosa; Membrane Glycoproteins; Membrane Proteins; Tumor Cells, Cultured; Vinblastine | 1992 |
Is forskolin stimulation of rat striatal tyrosine hydroxylase dependent on adenylate cyclase activation?
Topics: Adenylyl Cyclases; Animals; Colforsin; Corpus Striatum; Cyclic AMP; Enzyme Activation; In Vitro Techniques; Male; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Synaptosomes; Thionucleotides; Tyrosine 3-Monooxygenase | 1992 |
Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein.
Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloride Channels; Chlorides; Colforsin; Drug Resistance; Genetic Vectors; Humans; Ion Channels; Kinetics; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mice; Molecular Weight; Transfection; Vaccinia virus | 1992 |
1,9-Dideoxyforskolin does not mimic all cAMP and protein kinase A independent effects of forskolin on GABA activated ion currents in adult rat sensory neurons.
Topics: Animals; Colforsin; Cyclic AMP; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channels; Neurons, Afferent; Protein Kinases; Rats; Rats, Inbred Strains | 1992 |
A volume-sensitive chloride conductance revealed in cultured human keratinocytes by 36Cl- efflux and whole-cell patch clamp recording.
Topics: Biological Transport; Cells, Cultured; Chlorides; Colforsin; Gluconates; Humans; Keratinocytes; Membrane Potentials; Osmolar Concentration | 1992 |
Differential identification and localization of adenylyl cyclase and glucose transporter in brain using iodinated derivatives of forskolin.
Topics: Adenylyl Cyclases; Animals; Brain; Brain Chemistry; Cattle; Colforsin; Cytochalasin B; Glucose; Iodine Radioisotopes; Molecular Structure; Monosaccharide Transport Proteins; Radioligand Assay | 1992 |
Participation of pertussis toxin-sensitive GTP-binding regulatory proteins in the suppression of baroreceptor reflex by neurotensin in the rat.
Topics: Animals; Cholera Toxin; Colforsin; Ethylmaleimide; GTP-Binding Proteins; Male; Neurotensin; Pertussis Toxin; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1992 |
Alteration of the functional activity of Gs protein in thyrotropin-desensitized pig thyroid cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Second Messenger Systems; Swine; Thyroid Gland; Thyrotropin | 1991 |
Regulation of islet somatostatin secretion and gene expression: selective effects of adenosine 3',5'-monophosphate and phorbol esters in normal islets of Langerhans and in a somatostatin-producing rat islet clonal cell line 1027 B2.
Topics: Adenoma, Islet Cell; Animals; Animals, Newborn; Bucladesine; Colforsin; Cyclic AMP; Gene Expression Regulation; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Phorbol Esters; Rats; Rats, Inbred Strains; RNA, Messenger; Somatostatin; Theophylline; Tumor Cells, Cultured | 1991 |
Interaction of forskolin with the P-glycoprotein multidrug transporter.
Topics: Affinity Labels; Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Line; Cell Membrane; Colforsin; Doxorubicin; Drug Interactions; Drug Resistance; Female; Humans; Membrane Glycoproteins; Molecular Sequence Data; Molecular Weight; Neoplasm Proteins; Tumor Cells, Cultured | 1991 |
Transepithelial vinblastine secretion mediated by P-glycoprotein is inhibited by forskolin derivatives.
Topics: Adenylyl Cyclases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Colforsin; Dogs; Epithelium; Kidney; Membrane Glycoproteins; Verapamil; Vinblastine | 1991 |
Reversal of doxorubicin resistance by hydrophobic, but not hydrophilic, forskolins.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chemical Phenomena; Chemistry, Physical; Colforsin; Cyclic AMP; Doxorubicin; Drug Resistance; Membrane Glycoproteins; Mice; Sarcoma, Experimental; Signal Transduction; Tumor Cells, Cultured | 1991 |
Effects of forskolin and 1,9-dideoxy-forskolin on cochlear potentials.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cochlear Microphonic Potentials; Colforsin; Evoked Potentials, Auditory; Guinea Pigs | 1990 |
High affinity forskolin inhibition of L-type Ca2+ current in cardiac cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Colforsin; Cyclic AMP; In Vitro Techniques; Kinetics; Myocardium; Phosphorylation; Rana esculenta | 1990 |
Effects of forskolin and analogues on nicotinic receptor-mediated sodium flux, voltage-dependent calcium flux, and voltage-dependent rubidium efflux in pheochromocytoma PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Carbachol; Colforsin; Ion Channel Gating; Ion Channels; Neurotoxins; Pheochromocytoma; Potassium; Rats; Receptors, Nicotinic; Rubidium; Sodium; Tumor Cells, Cultured | 1990 |
Determination of levels of cyclic AMP in the myenteric plexus of guinea-pig small intestine.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Electrophysiology; Enzyme Activation; Ganglia; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Myenteric Plexus; Nerve Tissue Proteins | 1991 |
Regulation by forskolin of cyclic AMP phosphodiesterase and protein kinase C activity in LLC-PK1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Cells, Cultured; Colforsin; Cyclic GMP; Galactose; Macaca mulatta; Pregnenolone; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Effects of the adenylate cyclase activator forskolin and its inactive derivative 1,9-dideoxyforskolin on insect cytochrome P-450 dependent steroid hydroxylase activity.
Topics: Adenylyl Cyclases; Animals; Aryl Hydrocarbon Hydroxylases; Colforsin; Cytochrome P-450 Enzyme System; Drosophila melanogaster; Enzyme Activation; Larva; Moths; Steroid Hydroxylases | 1992 |
Effects of dideoxyforskolin on proteoglycan synthesis and structure in embryonic chick chondrocyte cultures.
Topics: Animals; Biopolymers; Cartilage; Cells, Cultured; Chick Embryo; Colforsin; Culture Media; Cyclic AMP; Diterpenes; Glycosaminoglycans; Glycosides; Proteoglycans; Sulfates | 1990 |
Induction of oligodendrocyte differentiation by activators of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Enzyme Induction; Oligodendroglia; Rats; Second Messenger Systems; Stimulation, Chemical | 1990 |
Forskolin but not isoprenaline increases sodium current from frog cardiac myocytes.
Topics: Animals; Colforsin; Heart; In Vitro Techniques; Isoproterenol; Membrane Potentials; Rana esculenta; Sodium Channels; Tetrodotoxin | 1990 |
Reduction of voltage-activated K+ currents by forskolin is not mediated via cAMP in pleural sensory neurons of Aplysia.
Topics: Adenylyl Cyclase Inhibitors; Animals; Aplysia; Colforsin; Cyclic AMP; Dimethyl Sulfoxide; Ganglia; Membrane Potentials; Neurons, Afferent; Potassium Channels | 1990 |
Locus of inhibitory action of cAMP-dependent protein kinase in the antigen receptor-triggered cytotoxic T lymphocyte activation pathway.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Cholera Toxin; Colforsin; Cyclic AMP; Cytotoxicity, Immunologic; Exocytosis; Lymphocyte Activation; Protein Kinases; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1988 |
Effect of forskolin on voltage-gated K+ channels is independent of adenylate cyclase activation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenal Gland Neoplasms; Colforsin; Cyclic AMP; Electric Conductivity; Enzyme Activation; Ion Channels; Kinetics; Pheochromocytoma; Potassium; Theophylline; Tumor Cells, Cultured | 1988 |
Forskolin alters acetylcholine receptor gating by a mechanism independent of adenylate cyclase activation.
Topics: Adenylyl Cyclases; Anesthetics, Local; Animals; Cloning, Molecular; Colforsin; Electric Conductivity; Enzyme Activation; Ion Channels; Receptors, Nicotinic; Torpedo; Xenopus laevis | 1988 |
Forskolin reduces a transient potassium current in lobster neurons by a cAMP-independent mechanism.
Topics: Animals; Colforsin; Cyclic AMP; Ganglia; Membrane Potentials; Nephropidae; Potassium Channels | 1989 |
Activation of adenylate cyclase by forskolin prolongs calcium action potential duration in lamprey sensory neurons.
Topics: Action Potentials; Adenylyl Cyclases; Animals; Calcium; Colforsin; Fishes; Lampreys | 1989 |
Partial reversal of doxorubicin resistance by forskolin and 1,9-dideoxyforskolin in murine sarcoma S180 variants.
Topics: Animals; Biological Transport; Cell Survival; Colforsin; Colony-Forming Units Assay; Cyclic AMP; Dose-Response Relationship, Drug; Drug Resistance; Sarcoma, Experimental; Tumor Cells, Cultured | 1988 |
Effect of forskolin and prostaglandin E1 on stimulus secretion coupling in cultured bovine adrenal chromaffin cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenal Glands; Alprostadil; Animals; Bucladesine; Calcimycin; Calcium; Cattle; Chromaffin System; Colforsin; Cyclic AMP; Drug Synergism; Nicotine; Norepinephrine; Potassium | 1988 |
Direct anesthetic-like effects of forskolin on the nicotinic acetylcholine receptors of PC12 cells.
Topics: Adenylyl Cyclases; Adrenal Gland Neoplasms; Anesthetics; Animals; Carbachol; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Pheochromocytoma; Rats; Receptors, Cholinergic; Rubidium; Time Factors | 1986 |
Activation of adenylate cyclase and inhibition of glucose transport in rat adipocytes by forskolin analogues: structural determinants for distinct sites of action.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Biological Transport, Active; Colforsin; Cytochalasin B; Diterpenes; Enzyme Activation; Glucose; Male; Rats | 1988 |
Forskolin and 3-isobutyl-1-methylxanthine increase basal and sodium nitroprusside-elevated cyclic GMP levels in adult guinea-pig cerebellar slices.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cerebellum; Colforsin; Cyclic AMP; Cyclic GMP; Ferrocyanides; Guinea Pigs; In Vitro Techniques; Nitric Oxide; Nitroprusside | 1994 |
Antagonism by forskolin of the 5-HT3 receptor-mediated current in nodose ganglion neurons is independent of cyclic AMP.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Colforsin; Cyclic AMP; Ion Channels; Isoquinolines; Neurons; Nodose Ganglion; Piperazines; Protein Kinase Inhibitors; Rats; Second Messenger Systems; Serotonin Antagonists | 1994 |
Transcription of the brain creatine kinase gene in glial cells is modulated by cyclic AMP-dependent protein kinase.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Brain; Brain Neoplasms; Cloning, Molecular; Colforsin; Creatine Kinase; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Energy Metabolism; Enzyme Activation; Enzyme Induction; Glioblastoma; Glioma; HeLa Cells; Humans; Isoenzymes; Isoquinolines; Myelin Sheath; Nerve Tissue Proteins; Neuroglia; Protein Synthesis Inhibitors; Rats; Recombinant Fusion Proteins; RNA, Antisense; Sulfonamides; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1994 |
Pathways involved in muscarinic M1 and M2 receptor stimulation in rabbit vas deferens.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adenylyl Cyclase Inhibitors; Animals; Carbachol; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Lithium Chloride; Male; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Phosphatidylinositols; Rabbits; Receptors, Muscarinic; Signal Transduction; Stereoisomerism; Tetradecanoylphorbol Acetate; Vas Deferens | 1994 |
Modulatory mechanisms of cyclic AMP-stimulated steroid content in rat brain cortex.
Topics: 1-Methyl-3-isobutylxanthine; Adrenalectomy; Animals; Benzodiazepinones; Bucladesine; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; In Vitro Techniques; Isoquinolines; Male; Orchiectomy; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear | 1994 |
Is cyclic AMP involved in excitatory amino acid-evoked adenosine release from rat cortical slices?
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Calcium; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Excitatory Amino Acids; Male; N-Methylaspartate; Parietal Lobe; Probenecid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Brefeldin A provokes indirect activation of cdc2 kinase (MPF) in Xenopus oocytes, resulting in meiotic cell division.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brefeldin A; CDC2 Protein Kinase; Cell Cycle; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Cyclopentanes; Enzyme Activation; Maturation-Promoting Factor; Meiosis; Oocytes; Oogenesis; Peptide Elongation Factor 1; Peptide Elongation Factors; Phosphorylation; Progesterone; Protamine Kinase; Protein Processing, Post-Translational; Signal Transduction; Xenopus laevis | 1995 |
Isolation of small polarized bile duct units.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicarbonates; Bile Ducts; Bucladesine; Chlorides; Cholestasis; Colforsin; Fluoresceins; Gluconates; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Microscopy, Electron; Microscopy, Video; Rats; Rats, Sprague-Dawley; Secretin; Time Factors | 1995 |
1-Acetyl-7-deacetylforskolin: a potential non-specific inactive analog of forskolin for estimation of its specific high-affinity binding and adenylyl cyclase stimulation in vitro.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Cyclic AMP; Endothelium, Vascular; Enzyme Activation; Humans; In Vitro Techniques; Prosencephalon; Rats; Umbilical Veins | 1995 |
Thapsigargin induces IL-2 receptor alpha-chain in human peripheral and Jurkat T cells via a protein kinase C-independent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Base Sequence; Calcimycin; Calcium; Calcium-Transporting ATPases; Cholera Toxin; Colforsin; Drug Synergism; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Humans; Hydroquinones; Isoquinolines; Leukemia-Lymphoma, Adult T-Cell; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Piperazines; Protein Kinase C; Receptors, Interleukin-2; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Staurosporine; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Cyclic adenosine-3',5'-monophosphate potentiates the synaptic potential mediated by NMDA receptors in the amygdala.
Topics: Amygdala; Animals; Bucladesine; Colforsin; Cyclic AMP; Electric Stimulation; Long-Term Potentiation; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Xanthines | 1995 |
Volume-activated chloride channels in HeLa cells are blocked by verapamil and dideoxyforskolin.
Topics: Adenosine Triphosphate; Chloride Channels; Chlorides; Colforsin; HeLa Cells; Humans; Hypotonic Solutions; Ion Channels; Membrane Potentials; Membrane Proteins; Osmosis; Verapamil | 1993 |
Pharmacologic properties of the swelling-induced chloride current of dog atrial myocytes.
Topics: Animals; Anthracenes; Atrial Function; Calcium; Chloride Channels; Colforsin; Dogs; Electrophysiology; Glycolates; Heart Atria; Niflumic Acid; Nitrobenzoates; Patch-Clamp Techniques; Stilbenes | 1994 |
Drug efflux mediated by the human multidrug resistance P-glycoprotein is inhibited by cell swelling.
Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Compartmentation; Cell Membrane Permeability; Chloride Channels; Colforsin; Doxorubicin; Drug Resistance, Multiple; Humans; Mice; Microscopy, Confocal; Osmotic Pressure; Recombinant Proteins; Verapamil | 1994 |
Evaluation of cAMP involvement in cannabinoid-induced antinociception.
Topics: Analgesics; Animals; Colforsin; Cyclic AMP; Cyclohexanols; Dronabinol; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley | 1995 |
Lack of inhibition by dideoxy-forskolin and verapamil of DIDS-sensitive volume-activated Cl- secretion in human squamous lung carcinoma epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Blotting, Western; Carcinoma, Squamous Cell; Cell Size; Chlorides; Colforsin; Humans; Lung Neoplasms; Osmolar Concentration; Tumor Cells, Cultured; Verapamil | 1994 |
Distinct mechanisms for Ca2+ entry induced by OKT3 and Ca2+ depletion in Jurkat T cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Calcium; Calcium Channel Blockers; Cations, Divalent; Cholera Toxin; Colforsin; Humans; Inositol Phosphates; Ion Channel Gating; Ion Transport; Lymphocyte Activation; Muromonab-CD3; Pertussis Toxin; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1995 |
Volume-activated Cl- currents in different mammalian non-excitable cell types.
Topics: Animals; Anura; Cell Line; Cell Physiological Phenomena; Chlorides; Colforsin; Electric Conductivity; Endothelium, Vascular; Epithelial Cells; Epithelium; Fibroblasts; Humans; Iodides; Mammals; Neoplasms; Nitrobenzoates; Permeability; Tamoxifen | 1994 |
Forskolin blocks the transient K current of rat cerebellar granule neurons.
Topics: Animals; Cerebellum; Colforsin; Cyclic AMP; Electric Conductivity; Electrophysiology; Neurons; Neuropeptides; Osmolar Concentration; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium; Rats; Time Factors | 1994 |
Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Colforsin; Docetaxel; Epithelium; Humans; Intestinal Absorption; Intestinal Mucosa; Membrane Glycoproteins; Nifedipine; Paclitaxel; Taxoids; Tumor Cells, Cultured; Verapamil; Vinblastine | 1993 |
NMDA receptor-mediated stimulation of rat cerebellar nitric oxide formation is modulated by cyclic AMP.
Topics: Animals; Cerebellum; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoquinolines; Male; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sulfonamides | 1994 |
Regulation of VLDL secretion in primary culture of rat hepatocytes: involvement of cAMP and cAMP-dependent protein kinases.
Topics: Animals; Apolipoproteins B; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Lipid Metabolism; Lipoproteins, VLDL; Liver; Male; Rats; Rats, Wistar | 1994 |
Adenosine reduces the potassium conductance of guinea pig submucosal plexus neurons by activating protein kinase A.
Topics: 2-Chloroadenosine; Adenosine; Alkaloids; Animals; Cadmium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Guinea Pigs; Membrane Potentials; Neurons; Phorbol 12,13-Dibutyrate; Potassium; Staurosporine; Submucous Plexus | 1993 |
Volume-regulatory taurine release from a human lung cancer cell line. Evidence for amino acid transport via a volume-activated chloride channel.
Topics: Amino Acids; Biological Transport; Chloride Channels; Colforsin; Humans; Iodides; Lung Neoplasms; Nitrobenzoates; Osmolar Concentration; Sodium; Taurine; Tumor Cells, Cultured | 1993 |
Forskolin inhibits platelet-activating factor binding to platelet receptors independently of adenylyl cyclase activation.
Topics: Adenylyl Cyclases; Animals; Blood Platelets; Cell Membrane; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; GTP-Binding Proteins; In Vitro Techniques; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Rabbits | 1993 |
Raised cyclic-AMP and a small applied electric field influence differentiation, shape, and orientation of single myoblasts.
Topics: Animals; Cell Differentiation; Cell Polarity; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Electromagnetic Fields; Muscles; Xenopus | 1993 |
Volume-sensitive chloride channels associated with human cervical carcinogenesis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Carcinoma in Situ; Carcinoma, Squamous Cell; Cell Transformation, Viral; Cervix Uteri; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; DNA Primers; DNA, Viral; Epithelium; Female; Humans; Ion Channel Gating; Molecular Sequence Data; Papillomaviridae; Tumor Cells, Cultured; Uterine Cervical Neoplasms; Verapamil; Water-Electrolyte Balance | 1995 |
Cyclic AMP-independent inhibition of voltage-sensitive calcium channels by forskolin in PC12 cells.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP; Ion Channel Gating; Nerve Tissue Proteins; PC12 Cells; Rats | 1996 |
Volume-sensitive chloride currents in primary cultures of human fetal vas deferens epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Bromides; Calcium; Cells, Cultured; Chloride Channels; Colforsin; Cyclic AMP; Epithelial Cells; Epithelium; Gluconates; Humans; Male; Tamoxifen; Time Factors; Vas Deferens | 1996 |
Regulation of 5-hydroxytryptamine-induced calcium mobilization by cAMP-elevating agents in cultured canine tracheal smooth muscle cells.
Topics: Adenine; Aluminum Compounds; Animals; Bucladesine; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diterpenes; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fluorides; GTP-Binding Proteins; Isoquinolines; Male; Muscle, Smooth; PC12 Cells; Rats; Serotonin; Serotonin Antagonists; Sulfonamides; Trachea | 1996 |
Forskolin's structural analogue 1,9-dideoxyforskolin has Ca2+ channel blocker-like action in rat cerebellar granule cells.
Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Colforsin; Dose-Response Relationship, Drug; Fura-2; Membrane Potentials; Patch-Clamp Techniques; Rats | 1996 |
Adenylate cyclase in striatal cholinergic interneurons regulates acetylcholine release.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenylyl Cyclases; Animals; Colforsin; Corpus Striatum; Cyclic AMP; Interneurons; Male; Parasympathetic Nervous System; Rats | 1996 |
Cyclic AMP-independent inhibition of cardiac calcium current by forskolin.
Topics: Animals; Binding Sites; Calcium; Calcium Channels; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Guinea Pigs; Heart; Heart Ventricles; Membrane Potentials; Stimulation, Chemical; Ventricular Function | 1996 |
Doxorubicin selection for MDR1/P-glycoprotein reduces swelling-activated K+ and Cl- currents in MES-SA cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Fluids; Chlorides; Colforsin; Doxorubicin; Drug Resistance, Multiple; Electric Conductivity; Female; Humans; Patch-Clamp Techniques; Potassium; RNA, Messenger; Stilbenes; Tumor Cells, Cultured; Verapamil | 1996 |
Effects of 1, 9-dideoxy forskolin on delayed rectifier potassium current of bullfrog dorsal root ganglion cells.
Topics: Animals; Cells, Cultured; Colforsin; Delayed Rectifier Potassium Channels; Ganglia, Spinal; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Rana catesbeiana | 1995 |
Essential role of adenosine triphosphate in activation of 17beta-hydroxysteroid dehydrogenase in the rat Leydig cell.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Aminoglutethimide; Animals; Chorionic Gonadotropin; Colforsin; Enzyme Activation; Hydroxysteroid Dehydrogenases; Leydig Cells; Male; Monosaccharide Transport Proteins; Rats; Rats, Sprague-Dawley; Testosterone | 1997 |
Cl- currents activated by extracellular nucleotides in human bronchial cells.
Topics: Adenosine Triphosphate; Bronchi; Calcium; Cells, Cultured; Chelating Agents; Chlorides; Colforsin; Cystic Fibrosis; Egtazic Acid; Epithelial Cells; Epithelium; Extracellular Space; Humans; Intracellular Fluid; Ion Transport; Membrane Potentials; Niflumic Acid; Patch-Clamp Techniques; Uridine Triphosphate | 1997 |
Biglycan gene promoter activity in osteosarcoma cells is regulated by cyclic AMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biglycan; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Indoles; Osteosarcoma; Plasmids; Promoter Regions, Genetic; Proteoglycans; Pyrroles; RNA, Messenger; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
Inhibition of [Ca2+]i transients in rat adrenal chromaffin cells by neuropeptide Y: role for a cGMP-dependent protein kinase-activated K+ conductance.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Glands; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cholinergic Agonists; Chromaffin Cells; Colforsin; Cyclic AMP; Cyclic GMP; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Male; Neuropeptide Y; Potassium; Potassium Channels; Rats; Rats, Wistar | 1997 |
Differential effects of forskolin and 1,9-dideoxy-forskolin on nicotinic receptor- and K+-induced responses in chromaffin cells.
Topics: Actins; Animals; Calcium; Calcium Channel Blockers; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Gelsolin; Membrane Potentials; Microfilament Proteins; Microscopy, Fluorescence; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Potassium | 1997 |
Volume regulation in NIH/3T3 cells not expressing P-glycoprotein. I. Regulatory volume decrease.
Topics: 3T3 Cells; 4-Aminopyridine; Animals; Anions; ATP Binding Cassette Transporter, Subfamily B, Member 1; Barium; Cell Membrane Permeability; Chloride Channels; Chlorides; Colchicine; Colforsin; Dipyridamole; Gramicidin; Kinetics; Mice; Niflumic Acid; Nitrobenzoates; Potassium Channel Blockers; Potassium Channels; Quinidine; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Water-Electrolyte Balance | 1997 |
Volume regulation in NIH/3T3 cells not expressing P-glycoprotein. II. Chloride and amino acid fluxes.
Topics: 3T3 Cells; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acids; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Calcium Channels; Chloride Channels; Chlorides; Colforsin; Dipyridamole; Fatty Acids, Nonesterified; Intracellular Fluid; Iodine Radioisotopes; Kinetics; Mice; Niflumic Acid; Nitrobenzoates; Osmolar Concentration; Taurine; Water-Electrolyte Balance | 1997 |
cAMP and forskolin inhibit potassium currents in rat taste receptor cells by different mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Bucladesine; Colforsin; Cyclic AMP; Female; In Vitro Techniques; Kinetics; Male; Patch-Clamp Techniques; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Taste Buds; Thionucleotides | 1997 |
Contribution of osmotic changes to disintegrative globulization of single cortical fibers isolated from rat lens.
Topics: Animals; Calcium; Cataract; Cells, Cultured; Chloride Channels; Colforsin; Edetic Acid; HEPES; Hypotonic Solutions; Lens Cortex, Crystalline; Nitrobenzoates; Osmosis; Rats; Sucrose | 1997 |
Activation of phosphodiesterase IV during desensitization of the A2A adenosine receptor-mediated cyclic AMP response in rat pheochromocytoma (PC12) cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adrenal Gland Neoplasms; Animals; Blotting, Western; Caffeine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Activation; Enzyme Inhibitors; Isoquinolines; Kinetics; PC12 Cells; Phenethylamines; Pheochromocytoma; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Recombinant Proteins; Sulfonamides | 1997 |
Modulation by extracellular Cl- of volume-activated organic osmolyte and halide permeabilities in HeLa cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Cell Membrane Permeability; Chloride Channels; Chlorides; Colforsin; HeLa Cells; Humans; Kinetics; Osmolar Concentration; Radioisotope Dilution Technique; Tamoxifen; Taurine; Tritium; Water-Electrolyte Balance | 1997 |
Inhibitory effect of dideoxyforskolin on cell death induced by ricin, modeccin, diphtheria toxin, and Pseudomonas toxin in MDCK cells.
Topics: Animals; Apoptosis; Bacterial Toxins; Brefeldin A; Calcium; Cell Death; Cell Line; Colforsin; Cyclopentanes; Diphtheria; DNA Fragmentation; Dogs; Kidney; Lectins; Plant Lectins; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Pseudomonas; Ribosome Inactivating Proteins, Type 2; Ricin | 1997 |
Therapy for X-adrenoleukodystrophy: normalization of very long chain fatty acids and inhibition of induction of cytokines by cAMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenoleukodystrophy; Animals; Astrocytes; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Enzyme Inhibitors; Fatty Acids; Genetic Linkage; Interleukin-1; Isoquinolines; Neuroglia; Oxidation-Reduction; Protein Kinase Inhibitors; Pyrrolidinones; Rats; Rolipram; Sulfonamides; Tumor Necrosis Factor-alpha; X Chromosome | 1998 |
Osmosensitive C1- currents and their relevance to regulatory volume decrease in human intestinal T84 cells: outwardly vs. inwardly rectifying currents.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Cadmium; Cell Line; Chloride Channels; CLC-2 Chloride Channels; Colforsin; Colonic Neoplasms; Humans; Hypertonic Solutions; Hypotonic Solutions; Intestinal Mucosa; Membrane Potentials; Nerve Tissue Proteins; Osmolar Concentration; Tamoxifen; Tumor Cells, Cultured | 1998 |
Regulation of cyclic AMP level by progesterone in ovariectomized rat neocortex.
Topics: Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Female; Neocortex; Ovariectomy; Ovary; Progesterone; Rats; Rats, Sprague-Dawley | 1999 |
FlCRhR/cyclic AMP signaling in myenteric ganglia and calbindin-D28 intrinsic primary afferent neurons involves adenylyl cyclases I, III and IV.
Topics: Action Potentials; Adenylyl Cyclases; Amidohydrolases; Animals; Antibody Specificity; Blotting, Western; Calbindins; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Duodenum; Electrophysiology; Ethylmaleimide; Fluorescent Antibody Technique; Fluorescent Dyes; Ganglia, Autonomic; Guinea Pigs; Isoenzymes; Jejunum; Microscopy, Confocal; Myenteric Plexus; Neuroglia; Neurons; Neurons, Afferent; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; S100 Calcium Binding Protein G; Signal Transduction | 1999 |
Voltage-activated K+ channels and membrane depolarization regulate accumulation of the cyclin-dependent kinase inhibitors p27(Kip1) and p21(CIP1) in glial progenitor cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Cycle Proteins; Cell Division; Cell Lineage; Cerebellum; Colforsin; Cyclin D; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Deferoxamine; Ion Channel Gating; Isoproterenol; Membrane Potentials; Mice; Microtubule-Associated Proteins; Oligodendroglia; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sirolimus; Stem Cells; Tetraethylammonium; Tumor Suppressor Proteins; Veratridine | 1999 |
Effect of protein kinase A-induced phosphorylation on the gating mechanism of the brain Na+ channel: model fitting to whole-cell current traces.
Topics: Animals; Brain; Cells, Cultured; Colforsin; Computer Simulation; Cyclic AMP-Dependent Protein Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Electrophysiology; Enzyme Inhibitors; Ion Channel Gating; Kinetics; Nerve Tissue Proteins; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Sodium Channels | 1999 |
Anion channel blockers differentially affect T-type Ca(2+) currents of mouse spermatogenic cells, alpha1E currents expressed in Xenopus oocytes and the sperm acrosome reaction.
Topics: Acrosome Reaction; Animals; Base Sequence; Calcium Channels; Colforsin; DNA Primers; DNA, Complementary; Female; In Vitro Techniques; Ion Channels; Male; Mice; Molecular Sequence Data; Niflumic Acid; Nitrobenzoates; Oocytes; Rats; Sequence Homology, Nucleic Acid; Spermatozoa; Xenopus laevis; Zona Pellucida | 1999 |
Adenylate cyclase and potassium channels are involved in forskolin- and 1,9-dideoxyforskolin-induced inhibition of pregnant rat uterus contractility.
Topics: Adenylyl Cyclases; Animals; Colforsin; Female; In Vitro Techniques; Potassium Channels; Pregnancy; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Uterine Contraction; Uterus | 2000 |
Volume sensitive efflux of taurine in HEK293 cells overexpressing phospholemman.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Cell Line; Cell Size; Colforsin; Down-Regulation; Humans; Iodine Radioisotopes; Ion Channels; Membrane Proteins; Nitrobenzoates; Osmolar Concentration; Phosphoproteins; Taurine; Transfection; Tritium | 2000 |
Interaction of cyclic AMP modulating agents with levcromakalim in the relaxation of rat isolated mesenteric artery.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Bucladesine; Colforsin; Cromakalim; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Glyburide; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Rats; Rats, Wistar; Thionucleotides; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2000 |
Pharmacological characterization of volume-sensitive, taurine permeable anion channels in rat supraoptic glial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetophenones; Adenosine Triphosphate; Animals; Calcium Channel Blockers; Chloride Channels; Colforsin; Diffusion; Dose-Response Relationship, Drug; Gene Expression; In Situ Hybridization; Ion Channels; Male; Mibefradil; Neuroglia; Niflumic Acid; Nitrobenzoates; ortho-Aminobenzoates; Osmotic Pressure; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Supraoptic Nucleus; Tamoxifen; Taurine | 2000 |
Contribution of the IsK (MinK) potassium channel subunit to regulatory volume decrease in murine tracheal epithelial cells.
Topics: Animals; Anti-Arrhythmia Agents; Apamin; Barium; Calcium Channels; Cells, Cultured; Cilia; Colforsin; Electrophysiology; Epithelial Cells; Mice; Mice, Knockout; Potassium Channels; Potassium Channels, Voltage-Gated; Quaternary Ammonium Compounds; Tamoxifen; Tetraethylammonium; Time Factors; Trachea | 2000 |
Differential actions of PKA and PKC in the regulation of glutamate release by group III mGluRs in the entorhinal cortex.
Topics: Adenine; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclopentanes; Entorhinal Cortex; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; In Vitro Techniques; Indoles; Isoquinolines; Male; Maleimides; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Sulfonamides; Tricarboxylic Acids | 2001 |
Effect of forskolin on acetylcholine-induced current in rat pheochromocytoma cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pheochromocytoma; Rats; Receptors, Nicotinic | 2000 |
The expression and regulation of depolarization-activated K+ channels in the insulin-secreting cell line INS-1.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Calcium; Colforsin; Electric Conductivity; Gene Expression Regulation; Insulin; Insulin Secretion; Insulinoma; Pancreatic Neoplasms; Potassium Channel Blockers; Potassium Channels; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetraethylammonium; Tolbutamide; Tumor Cells, Cultured | 2001 |
PKA modulation of Kv4.2-encoded A-type potassium channels requires formation of a supramolecular complex.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Substitution; Animals; Binding Sites; Calcium-Binding Proteins; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Kv Channel-Interacting Proteins; Macromolecular Substances; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Phosphopeptides; Phosphorylation; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Subunits; Repressor Proteins; Shal Potassium Channels; Structure-Activity Relationship; Transfection; Xenopus laevis | 2002 |
Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-X(L)- and PKB/AKT-independent fashion.
Topics: Adenosine Triphosphate; Apoptosis; bcl-X Protein; Blotting, Western; Caspases; Cell Fractionation; Colforsin; Colorimetry; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Fluorescent Dyes; Glucose; Glycolysis; Green Fluorescent Proteins; Humans; Jurkat Cells; Kinetics; Lactic Acid; Luminescent Proteins; Microscopy, Confocal; Mitochondria; Necrosis; Oxidative Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rhodamines | 2004 |
Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway.
Topics: Animals; Blotting, Northern; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Hepatocytes; Mice; Pharmaceutical Preparations; Phosphorylation; Plant Extracts; Plasmids; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Transfection; Xenobiotics | 2005 |
Analysis of glycoproteins in human colon cancers, normal tissues and in human colon carcinoma cells reactive with monoclonal antibody NCL-19-9.
Topics: Aged; Antibodies, Monoclonal; CA-19-9 Antigen; Cell Line, Tumor; Cell Proliferation; Colforsin; Colon; Colonic Neoplasms; Female; Glycoproteins; Humans; Immunoblotting; Male; Middle Aged; Molecular Weight | 2005 |
Block of spontaneous termination of paroxysmal depolarizations by forskolin (buccal ganglia, Helix pomatia).
Topics: Action Potentials; Animals; Colforsin; Drug Interactions; Electric Stimulation; Epilepsy; Ganglia, Invertebrate; Helix, Snails; Models, Neurological; Neurons; Pentylenetetrazole; Time Factors | 2006 |
Synthetic transformation of ptychantin into forskolin and 1,9-dideoxyforskolin.
Topics: Adenylyl Cyclases; Colforsin; Diterpenes; Glucose Transport Proteins, Facilitative | 2006 |
Tamoxifen does not inhibit the swell activated chloride channel in human neutrophils during the respiratory burst.
Topics: Cells, Cultured; Chloride Channels; Colforsin; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phloretin; Respiratory Burst; Superoxides; Tamoxifen; Tetradecanoylphorbol Acetate; Trialkyltin Compounds | 2008 |
The adenylyl cyclase-cAMP system suppresses TARC/CCL17 and MDC/CCL22 production through p38 MAPK and NF-kappaB in HaCaT keratinocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenylyl Cyclases; Bucladesine; Chemokine CCL17; Chemokine CCL22; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Interferon-gamma; Keratinocytes; Models, Immunological; NF-kappa B; p38 Mitogen-Activated Protein Kinases; STAT1 Transcription Factor; Thionucleotides; Tumor Necrosis Factor-alpha | 2009 |
Extracellular osmolarity modulates G protein-coupled receptor-dependent ATP release from 1321N1 astrocytoma cells.
Topics: Adenosine Triphosphate; Anions; Astrocytoma; Calcium Signaling; Carbenoxolone; Cell Line, Tumor; Chelating Agents; Colforsin; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Extracellular Fluid; Humans; Hypertonic Solutions; Hypotonic Solutions; Ion Channels; Kinetics; Osmolar Concentration; Probenecid; Receptor, PAR-1; rho GTP-Binding Proteins; Tetanus Toxin; Thrombin | 2010 |
Suppression of GLUT1; a new strategy to prevent diabetic complications.
Topics: Animals; beta-Crystallin B Chain; Blood Glucose; Brain; Brain Chemistry; Colforsin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Erythrocytes; Gene Knockdown Techniques; Gene Silencing; Genistein; Glucose; Glucose Transporter Type 1; Male; Mice; Protein Kinase Inhibitors; Retina; Superoxides; Vascular Endothelial Growth Factor A | 2013 |
Forskolin suppresses delayed-rectifier K+ currents and enhances spike frequency-dependent adaptation of sympathetic neurons.
Topics: Adaptation, Physiological; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Male; Membrane Potentials; Neurons; Rats; Shab Potassium Channels; Signal Transduction; Superior Cervical Ganglion | 2015 |