Compounds > 1,7-phenanthroline
Page last updated: 2024-08-24

1,7-phenanthroline and phenanthrenes

1,7-phenanthroline has been researched along with phenanthrenes in 87 studies

Research

Studies (87)

TimeframeStudies, this research(%)All Research%
pre-199023 (26.44)18.7374
1990's15 (17.24)18.2507
2000's17 (19.54)29.6817
2010's30 (34.48)24.3611
2020's2 (2.30)2.80

Authors

AuthorsStudies
Pan, LM; Zhan, S; Zhou, Y1
Barton, JK; Chow, CS; Hartmann, KM; Huber, PW; Rawlings, SL1
Barton, JK; Kirsch-De Mesmaeker, A; Orellana, G; Turro, NJ2
Liu, Y; Wang, B; Xie, P1
Ji, J; Luo, HW1
Han, GR1
Shi, YD1
Chen, GF1
Bao, XS; Chen, JZ; Guan, DP; Ni, XB; Wu, PJ; Yuan, JX1
Hu, XJ; Ji, J; Luo, HW; Wang, N1
Sansot, M1
Chen, Z1
Kong, DY; Liu, XJ1
Arkin, MR; Barton, JK; Bossmann, SH; Ghatlia, ND; Jenkins, Y; Murphy, CJ; Turro, NJ1
Barton, JK; Campisi, D; Morii, T1
Barton, JK; Lim, AC3
Armstrong, RN; Edwards, GH; Lacourciere, GM; Moos, M; Morris, DI; Tan, CP; Vakharia, VN1
Franklin, MR; Moody, DE; Slawson, MH1
Barton, JK; Franklin, SJ1
Barton, JK; Odom, DT; Parker, CS1
Chen, C; Guo, P; Mohammad, T; Morrison, H1
Blache, Y; Chapat, JP; Chavignon, O; Mallie, M; Mustof, M; Teulade, JC; Valentin, A; Yapi, AD1
Jia, JY; Leung, SW; Man, RY; Siow, YL; Yu, C; Zhang, H; Zhu, DY1
MACLEOD, RA1
SCHOLTIS, RJ1
WEBB, JL; YANASUGONDHA, D; YANG, WC1
ANGIONI, G1
DE BORBA, PQ; LOPES, E1
CARVALHO, O; SALGADO, JP1
COLSON, JA; PEREIRA, S; VANIER, G1
DA SILVA, AC; PINTO, NR1
NOHMI, N1
ATHANASIADOU, M; DAIKOS, GK1
SAFFER, D; SCHEIBL, F1
TURIAN, G1
BLANK, F1
Ishii, T; Kumagai, Y; Nakai, Y; Sugimoto, R1
Chow, MS; Zhou, L; Zuo, Z1
Chuang, TH; Lee, SJ; Wu, PL; Yang, CW1
Fürstner, A; Kennedy, JW1
Bláha, L; Burýsková, B; Hilscherová, K; Holoubek, I; Marsálek, B1
Bols, NC; Carlson, JC; DeWitte-Orr, SJ; Greenberg, BM; Nykamp, JA; Passaperuma, K; Peters, ZJ1
Chen, Q; Deng, L; Fu, H; Gong, T; Liu, J; Nie, Y; Wang, X; Zhang, ZR1
Bi, HC; Chen, X; Gu, LQ; Huang, M; Huang, ZY; Liu, PQ; Pan, Y; Zhao, LZ; Zhong, GP; Zhou, SF; Zuo, Z1
Leung, SW; Man, RY; Wan, AK; Zhu, DY1
Bohoyo Gil, D; Cano Carranza, E; Mora Diez, N; Muñoz de la Peña, A1
Lee, WY; Or, PM; Wang, X; Yeung, JH1
Chen, X; Liang, X; Shen, J; Tan, LF1
Ding, J; Feng, HJ; Li, YC; Li, Z; Lin, LP; Miao, ZH; Tong, LJ; Zhou, ZL1
Bastow, KF; Lee, KH; Lin, JC; Liu, YN; Shi, Q; Yang, PC; Yang, SC; Yang, X; Zhao, G1
Can, R; Mao, C; Shao, H; Wang, A; Wang, L; Xu, Z; Zhang, Y; Zhu, L1
Dai, H; Li, X; Li, Y; Wang, L; Wang, M; Xue, M1
Hu, C; Lin, HQ; Liu, S; Ngo, JC; Shaw, PC; Wan, DC; Wong, KK1
Bogatko, S; Cauët, E; Fusaro, L; Kirsch-De Mesmaeker, A; Luhmer, M; Mugeniwabagara, E; Vaeck, N1
Barnard, DL; Chao, YS; Huang, CW; Jan, JT; Kang, IJ; Lee, SJ; Lee, YZ; Lin, D; Yang, CW; Yeh, TK1
Georg, GI; Niphakis, MJ1
Brezovský, J; Hofman, J; Kobetičová, K; Simek, Z1
Chen, XG; Li, HY; Liu, ZJ; Lv, HN; Si, YK; Su, FQ; Yu, SS; Zhang, HJ; Zhang, Y1
Kwan, YW; Lee, WY; Or, PM; Yeung, JH; Zhou, X1
Blunt, M; David, CC; De Feyter, S; Kirsch-De Mesmaeker, A; Moucheron, C; Vanderlinden, W1
Liu, Y; Wang, L; Wang, Q; Wang, Z; Wei, P; Xizhi, X1
Liu, Y; Park, CM; Xu, X1
Chen, G; Chen, W; Huang, S; Lu, Y1
Opatz, T; Peez, TE; Stoye, A1
Abliz, Z; Chen, X; Chen, Y; Fu, Z; Gong, T; He, J; Huang, L; Luo, Z; Lv, H; Ma, S; Tang, F; Wang, X; Yu, S; Zhang, L; Zhang, R1
Chang, HY; Chao, YS; Hsu, HY; Lee, SJ; Lee, YZ; Wu, CM; Yang, CW1
Guo, M; Liang, J; Meng, J; Wu, S; Yang, Z1
Chang, CC; Ho, TF; Huang, LR; Lai, JS; Liao, EC; Lin, JY; Lu, CH; Ma, SW; Tsai, CS1
Chen, F; Su, B; Wang, L; Wang, Q1
KRADOLFER, F; NEIPP, L1
Liu, Y; Wang, Q; Zheng, Y1
Deng, M; Su, B; Wang, Q; Zhang, H1
Anton-Torrecillas, C; Gonzalez-Gomez, JC1
Ambrosek, D; Assfeld, X; Daniel, C; Gourlaouen, C; Monari, A; Otsuka, M; Véry, T1
Liu, Y; Wang, Q; Wang, Z; Wei, P1
Kim, I; Kim, S; Kwon, Y1
Liu, Y; Wang, L; Wang, Q; Wang, Z; Wei, P; Yu, X1
Liu, GQ; Opatz, T; Reimann, M1
Yamaoka, Y1
Bessho, Y; Deai, K; Hata, T; Kosugi, Y; Kurimoto, T; Matsushita, M; Misaki, S; Miyai, A; Nakagawa, T; Negoro, T; Tamai, I; Yamaguchi, T; Yamamoto, Y1
Liu, F; Zhang, L1
Frederickx, W; Kolbeck, PJ; Konrad, SF; Lampe, C; Lipfert, J; Moucheron, C; Nicolaus, T; Urban, AS; Vanderlinden, W1
Banasiak, A; Chatgilialoglu, C; Clynes, M; Colleran, J; Fantoni, NZ; Kellett, A; Kelly, S; Krokidis, MG; McKee, V; Menounou, G; Mitrikas, G; Molphy, Z; O'Carroll, S; Roche, S1
Abdalla, AN; Abdullah, O; Chen, L; Fischer, PM; Guise, CP; Liu, Y; Omran, Z; Patterson, AV; Rauch, C; Sindi, IA; Smaill, JB; Wang, Q1

Reviews

3 review(s) available for 1,7-phenanthroline and phenanthrenes

ArticleYear
Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:12

    Topics: Abietanes; Angina Pectoris; Animals; Benzofurans; Drugs, Chinese Herbal; Fibrinolytic Agents; Herb-Drug Interactions; Humans; Hyperlipidemias; Lactates; Phenanthrenes; Phenanthrolines; Plant Extracts; Randomized Controlled Trials as Topic; Salvia miltiorrhiza; Stroke

2005
Molecular evidence of cryptotanshinone for treatment and prevention of human cancer.
    Anti-cancer agents in medicinal chemistry, 2013, Volume: 13, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; Drugs, Chinese Herbal; Humans; Neoplasms; Phenanthrenes; Phenanthrolines; Salvia miltiorrhiza; TOR Serine-Threonine Kinases

2013
Efficient Synthesis of Polyaromatic Hydrocarbon via a Formal [2+2] Cycloaddition.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2016, Volume: 136, Issue:11

    Topics: Alkaloids; Cyclization; Cycloaddition Reaction; Heterocyclic Compounds; Hydrogenation; Indolizines; Phenanthrenes; Phenanthrolines; Polycyclic Aromatic Hydrocarbons

2016

Other Studies

84 other study(ies) available for 1,7-phenanthroline and phenanthrenes

ArticleYear
[Studies and preparations of fufang danshen granules].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1992, Volume: 17, Issue:9

    Topics: Abietanes; beta-Cyclodextrins; Chromatography, Thin Layer; Cyclodextrins; Drug Combinations; Drugs, Chinese Herbal; Excipients; Phenanthrenes; Phenanthrolines; Plant Extracts; Quality Control; Salvia miltiorrhiza; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical

1992
Delineation of structural domains in eukaryotic 5S rRNA with a rhodium probe.
    Biochemistry, 1992, Apr-07, Volume: 31, Issue:13

    Topics: Animals; Base Sequence; Binding Sites; Intercalating Agents; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Oocytes; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Photochemistry; Rhodium; RNA, Ribosomal, 5S; Xenopus

1992
Photoinduced electron transfer quenching of excited Ru(II) polypyridyls bound to DNA: the role of the nucleic acid double helix.
    Photochemistry and photobiology, 1991, Volume: 54, Issue:4

    Topics: Aza Compounds; Chelating Agents; Chromium; Cobalt; DNA; Electron Transport; Ethidium; Nucleic Acid Conformation; Organometallic Compounds; Oxidation-Reduction; Paraquat; Phenanthrenes; Phenanthrolines; Poly dA-dT; Rhodium; Ruthenium

1991
[Evaluation of radix Salviae Miltiorrhizae and its preparation].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1990, Volume: 15, Issue:3

    Topics: Abietanes; Benzaldehydes; Catechols; Chromatography, Thin Layer; Densitometry; Drug Combinations; Drugs, Chinese Herbal; Lactates; Phenanthrenes; Phenanthrolines; Plant Extracts; Salvia miltiorrhiza; Tablets

1990
Ligand-dependent interaction of ruthenium(II) polypyridyl complexes with DNA probed by emission spectroscopy.
    Photochemistry and photobiology, 1990, Volume: 52, Issue:3

    Topics: 2,2'-Dipyridyl; DNA; Kinetics; Ligands; Phenanthrenes; Phenanthrolines; Poly dA-dT; Pyridines; Ruthenium; Spectrophotometry

1990
[Identification of tanshinones with related compounds by high performance thin layer chromatography and mass spectrometric analysis].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1989, Volume: 24, Issue:5

    Topics: Abietanes; Anticoagulants; Chromatography, High Pressure Liquid; Diterpenes; Drug Combinations; Drugs, Chinese Herbal; Mass Spectrometry; Phenanthrenes; Phenanthrolines; Plant Extracts; Salvia miltiorrhiza

1989
[Water soluble constituents from radix Salvia miltiorrhiza before and after slicing].
    Zhong yao tong bao (Beijing, China : 1981), 1985, Volume: 10, Issue:11

    Topics: Abietanes; Benzaldehydes; Catechols; Drug Combinations; Drugs, Chinese Herbal; Medicine, Chinese Traditional; Phenanthrenes; Phenanthrolines; Phenols; Plant Extracts; Plants, Medicinal; Salvia miltiorrhiza; Solubility; Technology, Pharmaceutical; Water

1985
[Anti-coagulation effect in vitro of danshan and its three chemical extracts].
    Zhong yao tong bao (Beijing, China : 1981), 1986, Volume: 11, Issue:7

    Topics: Abietanes; Anticoagulants; Benzaldehydes; Blood Viscosity; Catechols; Drug Combinations; Drugs, Chinese Herbal; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Phenanthrenes; Phenanthrolines; Plant Extracts; Plants, Medicinal; Salvia miltiorrhiza

1986
[High performance liquid chromotographic determination of two tanshinones and the chromotographic profiles of 15 danshens].
    Zhong yao tong bao (Beijing, China : 1981), 1987, Volume: 12, Issue:5

    Topics: Abietanes; Anti-Infective Agents; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Medicine, Chinese Traditional; Phenanthrenes; Phenanthrolines; Plant Extracts; Plants, Medicinal; Salvia miltiorrhiza; Species Specificity

1987
[Quality evaluation of cultivated Salvia miltiorrhiza Bge. in Chongming, a suburb of Shanghai].
    Zhong yao tong bao (Beijing, China : 1981), 1988, Volume: 13, Issue:6

    Topics: Abietanes; Benzaldehydes; Catechols; Drug Combinations; Drugs, Chinese Herbal; Pharmacognosy; Phenanthrenes; Phenanthrolines; Plant Extracts; Plants, Medicinal; Salvia miltiorrhiza

1988
[Platelet aggregation inhibitors from Salvia miltiorrhiza Bunge].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:11

    Topics: Animals; Diterpenes; Drug Combinations; Drugs, Chinese Herbal; Phenanthrenes; Phenanthrolines; Plant Extracts; Platelet Aggregation Inhibitors; Rabbits; Salvia miltiorrhiza

1988
[The treatment of acute diarrheas in infants by granulated Mexaforme].
    Marseille medical, 1967, Volume: 104, Issue:3

    Topics: Amebicides; Child, Preschool; Clioquinol; Diarrhea, Infantile; Female; Humans; Infant; Infant, Newborn; Male; Mandelic Acids; Parasympatholytics; Phenanthrenes; Phenanthrolines; Quaternary Ammonium Compounds

1967
[The relationship between root growth and cryptotanshinone content of Salvia miltiorrhiza].
    Zhong yao tong bao (Beijing, China : 1981), 1983, Volume: 8, Issue:1

    Topics: Drug Combinations; Drugs, Chinese Herbal; Phenanthrenes; Phenanthrolines; Plant Extracts; Plants, Medicinal; Salvia miltiorrhiza

1983
[Structure of dihydroisotanshinone I of danshen].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1984, Volume: 19, Issue:10

    Topics: Chemical Phenomena; Chemistry; Drug Combinations; Drugs, Chinese Herbal; Phenanthrenes; Phenanthrolines; Plant Extracts; Salvia miltiorrhiza

1984
Long-range photoinduced electron transfer through a DNA helix.
    Science (New York, N.Y.), 1993, Nov-12, Volume: 262, Issue:5136

    Topics: Base Sequence; DNA; Electrons; Intercalating Agents; Lasers; Luminescence; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Photochemistry

1993
Correlations of crystal structures of DNA oligonucleotides with enantioselective recognition by Rh(phen)2phi3+: probes of DNA propeller twisting in solution.
    Biochemistry, 1994, Apr-12, Volume: 33, Issue:14

    Topics: Base Sequence; Binding Sites; Crystallization; DNA; Molecular Sequence Data; Nucleic Acid Conformation; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Photochemistry; Solutions; Stereoisomerism

1994
Chemical probing of tDNAPhe with transition metal complexes: a structural comparison of RNA and DNA.
    Biochemistry, 1993, Oct-19, Volume: 32, Issue:41

    Topics: DNA; Intercalating Agents; Models, Molecular; Nucleic Acid Conformation; Organometallic Compounds; Phenanthrenes; Phenanthrolines; RNA, Transfer, Phe

1993
Interaction of hepatic microsomal epoxide hydrolase derived from a recombinant baculovirus expression system with an azarene oxide and an aziridine substrate analogue.
    Biochemistry, 1993, Mar-16, Volume: 32, Issue:10

    Topics: Animals; Baculoviridae; Cell Line; Chromatography; Chromatography, DEAE-Cellulose; Cloning, Molecular; Durapatite; Electrophoresis, Polyacrylamide Gel; Epoxide Hydrolases; Genetic Vectors; Hydroxyapatites; Insecta; Kinetics; Mathematics; Microsomes, Liver; Molecular Weight; Moths; Phenanthrenes; Phenanthrolines; Recombinant Proteins; Restriction Mapping; Substrate Specificity; Transfection

1993
Selective induction of rat liver phase II enzymes by N-heterocycle analogues of phenanthrene: a response exhibiting high correlation between UDP-glucuronosyltransferase and microsomal epoxide hydrolase activities.
    Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:3

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Induction; Epoxide Hydrolases; Glucuronosyltransferase; Isoenzymes; Liver; Male; Microsomes, Liver; Oxygenases; Phenanthrenes; Phenanthrolines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1993
Targeting the Tat-binding site of bovine immunodeficiency virus TAR RNA with a shape-selective rhodium complex.
    Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:6

    Topics: Animals; Antiviral Agents; Binding Sites; Cattle; Gene Products, tat; Immunodeficiency Virus, Bovine; Kinetics; Nucleic Acid Conformation; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Rhodium; RNA, Viral; Structure-Activity Relationship; Substrate Specificity; Viral Proteins

1997
Rh(phen)2phi3+ as a shape-selective probe of triple helices.
    Biochemistry, 1998, Jun-23, Volume: 37, Issue:25

    Topics: Base Composition; Hydrolysis; Intercalating Agents; Nucleic Acid Conformation; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Photochemistry; Purine Nucleotides; Pyrimidine Nucleotides; RNA; RNA Probes; Salts

1998
Differential DNA recognition by the enantiomers of 1-Rh(MGP)2 phi: a combination of shape selection and direct readout.
    Biochemistry, 1998, Nov-17, Volume: 37, Issue:46

    Topics: Binding Sites; Computer Simulation; DNA; Guanidine; Intercalating Agents; Kinetics; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Photochemistry; Rhodium; Stereoisomerism; Titrimetry

1998
Site-specific inhibition of transcription factor binding to DNA by a metallointercalator.
    Biochemistry, 1999, Apr-20, Volume: 38, Issue:16

    Topics: Binding Sites; Binding, Competitive; DNA; DNA-Binding Proteins; Fungal Proteins; Intercalating Agents; Models, Molecular; Oligonucleotides; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Photolysis; Protein Binding; Recombinant Proteins; Rhodium; Saccharomyces cerevisiae Proteins; Transcription Factors

1999
Photoinduced cross-linking of RNA by cis-Rh(phen)2Cl2+ and cis-Rh(phen)(phi)Cl2+: a new family of light activatable nucleic acid cross-linking agents.
    Bioorganic & medicinal chemistry letters, 1999, Jun-21, Volume: 9, Issue:12

    Topics: Bacillus Phages; Base Sequence; Cross-Linking Reagents; Guanine; Light; Molecular Sequence Data; Nucleic Acid Conformation; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Photochemistry; RNA, Viral

1999
New potential antimalarial agents: synthesis and biological activities of original diaza-analogs of phenanthrene.
    Chemical & pharmaceutical bulletin, 2000, Volume: 48, Issue:12

    Topics: Animals; Antimalarials; Chelating Agents; Drug Evaluation, Preclinical; HeLa Cells; Humans; Inhibitory Concentration 50; Phenanthrenes; Phenanthrolines; Plasmodium falciparum

2000
Contents of four active components in different commercial crude drugs and preparations of danshen (Salvia miltiorrhiza).
    Acta pharmacologica Sinica, 2002, Volume: 23, Issue:12

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Injections; Lactates; Magnesium; Phenanthrenes; Phenanthrolines; Plants, Medicinal; Salvia miltiorrhiza; Tablets

2002
The toxicity of o-phenanthroline for lactic acid bacteria.
    The Journal of biological chemistry, 1952, Volume: 197, Issue:2

    Topics: Lactic Acid; Lactobacillus; Phenanthrenes; Phenanthrolines

1952
[Blood iron determination by 1,1-phenanthroline].
    Nederlands tijdschrift voor geneeskunde, 1954, Jun-12, Volume: 98, Issue:24

    Topics: Blood; Iron; Phenanthrenes; Phenanthrolines

1954
The inhibition of mitochondrial respiration by 1,10-phenanthroline and 2,2'-bipyridine and the possible relationship to oxidative phosphorylation.
    The Journal of biological chemistry, 1958, Volume: 232, Issue:2

    Topics: 2,2'-Dipyridyl; Cell Respiration; Chelating Agents; Humans; Mitochondria; Oxidative Phosphorylation; Phenanthrenes; Phenanthrolines; Pyridines

1958
[Preliminary note on the therapy of intestinal amebiasis with phenanthroline-quinone derivatives (entobex)].
    Minerva medica, 1958, Jun-20, Volume: 49, Issue:49

    Topics: Amebiasis; Dysentery, Amebic; Humans; Phenanthrenes; Phenanthrolines; Quinones

1958
[Trials of a new amebicidal derivative of phenanthroline-quinone].
    Hospital (Rio de Janeiro, Brazil), 1958, Volume: 54, Issue:2

    Topics: Amebiasis; Amebicides; Dysentery, Amebic; Phenanthrenes; Phenanthrolines; Quinones

1958
[Treatment of amebiasis in pediatric clinical practice with a new derivative of the quinone-phenanthroline group].
    Jornal de pediatria, 1958, Volume: 23, Issue:10

    Topics: Amebiasis; Phenanthrenes; Phenanthrolines; Quinones

1958
[A new antiamebic drugs: 4, 7-phenanthroline-5, 6-quinone; clinical results].
    Maroc medical, 1958, Volume: 37, Issue:402

    Topics: Amebiasis; Dysentery, Amebic; Phenanthrenes; Phenanthrolines; Quinones

1958
[New treatment for amebic dysentery: 4,7-phenanthroline-5,6-quinone].
    Hospital (Rio de Janeiro, Brazil), 1959, Volume: 55, Issue:1

    Topics: Amebiasis; Dysentery, Amebic; Intestines; Phenanthrenes; Phenanthrolines; Quinones

1959
[Treatment of intestinal amebiasis with phenanthroline quinone & iodochlorhydroxyquin].
    Revista brasileira de medicina, 1958, Volume: 15, Issue:8

    Topics: Amebiasis; Anti-Infective Agents, Local; Clioquinol; Dysentery, Amebic; Halogens; Hydrocarbons, Halogenated; Intestines; Phenanthrenes; Phenanthrolines; Quinones

1958
A new phenanthroline-quinone for the treatment of amoebiasis.
    The Journal of tropical medicine and hygiene, 1959, Volume: 62, Issue:6

    Topics: Amebiasis; Bronchi; Dysentery, Amebic; Fistula; Phenanthrenes; Phenanthrolines; Quinones

1959
[Determination of serum iron with o-phenanthroline].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1954, Volume: 298, Issue:6

    Topics: Blood; Iron; Phenanthrenes; Phenanthrolines

1954
[Tuberculostatic action of o-phenanthroline].
    Schweizerische Zeitschrift fur Pathologie und Bakteriologie. Revue suisse de pathologie et de bacteriologie, 1951, Volume: 14, Issue:3

    Topics: Mycobacterium tuberculosis; Phenanthrenes; Phenanthrolines

1951
In vitro fungistatic action of phenanthrolines against pathogenic fungi.
    Nature, 1951, Sep-22, Volume: 168, Issue:4273

    Topics: Antifungal Agents; Fungi; Fungicides, Industrial; In Vitro Techniques; Phenanthrenes; Phenanthrolines; Triazoles

1951
9,10-Phenanthraquinone in diesel exhaust particles downregulates Cu,Zn-SOD and HO-1 in human pulmonary epithelial cells: intracellular iron scavenger 1,10-phenanthroline affords protection against apoptosis.
    Free radical biology & medicine, 2005, Feb-01, Volume: 38, Issue:3

    Topics: Apoptosis; Cell Line; Cell Survival; Cytochrome P-450 Enzyme System; Ditiocarb; Electron Spin Resonance Spectroscopy; Epithelial Cells; Free Radical Scavengers; Free Radicals; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Iron Chelating Agents; Membrane Proteins; Phenanthrenes; Phenanthrolines; Pulmonary Alveoli; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Vehicle Emissions

2005
Expedient synthesis and structure-activity relationships of phenanthroindolizidine and phenanthroquinolizidine alkaloids.
    Organic & biomolecular chemistry, 2006, Mar-07, Volume: 4, Issue:5

    Topics: Alkaloids; Antineoplastic Agents; Biochemistry; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Indolizines; Phenanthrenes; Phenanthrolines; Quinolizines; Structure-Activity Relationship

2006
Total syntheses of the tylophora alkaloids cryptopleurine, (-)-antofine, (-)-tylophorine, and (-)-ficuseptine C.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2006, Sep-25, Volume: 12, Issue:28

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Indoles; Indolizines; Phenanthrenes; Phenanthrolines

2006
Toxicity and modulations of biomarkers in Xenopus laevis embryos exposed to polycyclic aromatic hydrocarbons and their N-heterocyclic derivatives.
    Environmental toxicology, 2006, Volume: 21, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Biomarkers; Embryo, Nonmammalian; Environmental Pollutants; Female; Heterocyclic Compounds, 3-Ring; Humans; Male; Phenanthrenes; Phenanthrolines; Polycyclic Aromatic Hydrocarbons; Toxicity Tests; Xenopus laevis

2006
Effect of copper on the cytotoxicity of phenanthrene and 9,10-phenanthrenequinone to the human placental cell line, JEG-3.
    Reproductive toxicology (Elmsford, N.Y.), 2007, Volume: 23, Issue:4

    Topics: Anthracenes; Anthraquinones; Cell Line, Tumor; Cell Survival; Chelating Agents; Copper; Dose-Response Relationship, Drug; Drug Synergism; Energy Metabolism; Environmental Pollutants; Humans; Oxidation-Reduction; Oxidative Stress; Phenanthrenes; Phenanthrolines; Placenta; Reactive Oxygen Species; Trophoblasts

2007
Simultaneous determination and pharmacokinetic study of water-soluble and lipid-soluble components of danshen in rat plasma using HPLC-UV method.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:11

    Topics: Abietanes; Animals; Benzofurans; Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Hydrophobic and Hydrophilic Interactions; Lipids; Molecular Structure; Phenanthrenes; Phenanthrolines; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Salvia miltiorrhiza; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Water

2007
Pharmacokinetic characterization of hydroxylpropyl-beta-cyclodextrin-included complex of cryptotanshinone, an investigational cardiovascular drug purified from Danshen (Salvia miltiorrhiza).
    Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:4

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Abietanes; Administration, Oral; Animals; beta-Cyclodextrins; Cardiovascular Agents; Dogs; Drugs, Chinese Herbal; Drugs, Investigational; Female; Male; Phenanthrenes; Phenanthrolines; Rats; Salvia miltiorrhiza; Tissue Distribution

2008
Vascular effects of different lipophilic components of "Danshen", a traditional Chinese medicine, in the isolated porcine coronary artery.
    Journal of natural products, 2008, Volume: 71, Issue:11

    Topics: Abietanes; Animals; Coronary Vessels; Diterpenes; Drugs, Chinese Herbal; Humans; Lipids; Medicine, Chinese Traditional; Molecular Structure; Phenanthrenes; Phenanthrolines; Plant Roots; Quinones; Salvia miltiorrhiza; Sus scrofa

2008
Second-order data obtained by time-resolved room temperature phosphorescence. A new approach for PARAFAC multicomponent analysis.
    Journal of fluorescence, 2009, Volume: 19, Issue:2

    Topics: beta-Cyclodextrins; Complex Mixtures; Luminescent Measurements; Phenanthrenes; Phenanthrolines; Solutions

2009
Effects of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on rat CYP1A2 expression and metabolism of model CYP1A2 probe substrates.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2009, Volume: 16, Issue:8

    Topics: Abietanes; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Drugs, Chinese Herbal; Half-Life; Male; Metabolic Clearance Rate; Phenacetin; Phenanthrenes; Phenanthrolines; Plant Extracts; Plant Roots; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza

2009
In vitro study on DNA binding of ruthenium(II) complexes with polypyridyl ligands.
    DNA and cell biology, 2009, Volume: 28, Issue:9

    Topics: 2,2'-Dipyridyl; Animals; Binding Sites; Cattle; Circular Dichroism; DNA; Intercalating Agents; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Ruthenium; Spectrometry, Fluorescence; Stereoisomerism

2009
Design and synthesis of novel C14-hydroxyl substituted triptolide derivatives as potential selective antitumor agents.
    Journal of medicinal chemistry, 2009, Aug-27, Volume: 52, Issue:16

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Diterpenes; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Epoxy Compounds; Humans; Mice; Mice, Nude; Phenanthrenes; Phenanthrolines; Stereoisomerism; Structure-Activity Relationship

2009
Antitumor agents 268. Design, synthesis, and mechanistic studies of new 9-substituted phenanthrene-based tylophorine analogues as potent cytotoxic agents.
    Journal of medicinal chemistry, 2009, Aug-27, Volume: 52, Issue:16

    Topics: Alkaloids; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Indolizines; Models, Molecular; Molecular Conformation; NF-kappa B; Phenanthrenes; Phenanthrolines; Piperidines; Proto-Oncogene Proteins c-akt; Signal Transduction; Stereoisomerism; Structure-Activity Relationship

2009
The effect of tanshinone IIA on renal and liver functions in ovine fetuses in utero.
    Drug and chemical toxicology, 2009, Volume: 32, Issue:4

    Topics: Abietanes; Animals; Drugs, Chinese Herbal; Female; Fetus; KCNQ1 Potassium Channel; Kidney; Liver; Microsomes, Liver; Phenanthrenes; Phenanthrolines; Pregnancy; Pregnancy, Animal; Salvia miltiorrhiza; Sheep; Uterus

2009
Structural elucidation of metabolites of tanshinone I and its analogue dihydrotanshinone I in rats by HPLC-ESI-MSn.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Apr-15, Volume: 878, Issue:13-14

    Topics: Abietanes; Animals; Biotransformation; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Hydroxylation; Male; Molecular Structure; Oxidation-Reduction; Phenanthrenes; Phenanthrolines; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Spectrometry, Mass, Electrospray Ionization

2010
Interaction study of two diterpenes, cryptotanshinone and dihydrotanshinone, to human acetylcholinesterase and butyrylcholinesterase by molecular docking and kinetic analysis.
    Chemico-biological interactions, 2010, Sep-06, Volume: 187, Issue:1-3

    Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Diterpenes; Drugs, Chinese Herbal; Humans; Models, Molecular; Phenanthrenes; Phenanthrolines; Protein Binding; Protein Conformation; Salvia miltiorrhiza; Sequence Homology, Amino Acid

2010
Density functional theory interpretation of the 1H photo-chemically induced dynamic nuclear polarization enhancements characterizing photoreduced polyazaaromatic Ru(II) coordination complexes.
    Inorganic chemistry, 2010, Sep-06, Volume: 49, Issue:17

    Topics: Models, Molecular; Organometallic Compounds; Oxidation-Reduction; Phenanthrenes; Phenanthrolines; Photochemical Processes; Quantum Theory; Ruthenium

2010
Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus.
    Antiviral research, 2010, Volume: 88, Issue:2

    Topics: Alkaloids; Animals; Antiviral Agents; Apocynaceae; Chlorocebus aethiops; Coronavirus Infections; Cytopathogenic Effect, Viral; Dose-Response Relationship, Drug; Gastroenteritis, Transmissible, of Swine; Indolizines; Phenanthrenes; Phenanthrolines; Quinolizines; Rats; Rats, Sprague-Dawley; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Structure-Activity Relationship; Swine; Transmissible gastroenteritis virus; Tylophora; Vero Cells

2010
Synthesis of tylocrebrine and related phenanthroindolizidines by VOF3-mediated oxidative aryl-alkene coupling.
    Organic letters, 2011, Jan-21, Volume: 13, Issue:2

    Topics: Alkenes; Catalysis; Combinatorial Chemistry Techniques; Indolizines; Molecular Structure; Oxidative Coupling; Oxides; Phenanthrenes; Phenanthrolines; Stereoisomerism; Structure-Activity Relationship; Tetrahydroisoquinolines; Vanadium

2011
Toxic effects of nine polycyclic aromatic compounds on Enchytraeus crypticus in artificial soil in relation to their properties.
    Ecotoxicology and environmental safety, 2011, Volume: 74, Issue:6

    Topics: Acridines; Animals; Anthracenes; Nitrogen; Oligochaeta; Phenanthrenes; Phenanthrolines; Polycyclic Aromatic Hydrocarbons; Quantitative Structure-Activity Relationship; Quinolines; Reproduction; Soil; Soil Pollutants

2011
Anticancer effect and neurotoxicity of S-(+)-deoxytylophorinidine, a new phenanthroindolizidine alkaloid that interacts with nucleic acids.
    Journal of Asian natural products research, 2011, Volume: 13, Issue:5

    Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Indolizines; Mice; Neurotoxicity Syndromes; Nucleic Acids; PC12 Cells; Phenanthrenes; Phenanthrolines; Plant Roots; Rats; Transplantation, Heterologous; Tylophora; Vinblastine

2011
Tanshinone I increases CYP1A2 protein expression and enzyme activity in primary rat hepatocytes.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Jan-15, Volume: 19, Issue:2

    Topics: Abietanes; Animals; Benzofurans; Cell Survival; Cytochrome P-450 CYP1A2; Cytochromes; Drugs, Chinese Herbal; Enzyme Activation; Enzyme Induction; Ethanol; Hepatocytes; Male; Phenacetin; Phenanthrenes; Phenanthrolines; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; RNA, Messenger; Salvia miltiorrhiza; Tacrine

2012
Mesoscale DNA structural changes on binding and photoreaction with Ru[(TAP)2PHEHAT]2+.
    Journal of the American Chemical Society, 2012, Jun-20, Volume: 134, Issue:24

    Topics: Aza Compounds; Chrysenes; DNA; Intercalating Agents; Light; Nucleic Acid Conformation; Phenanthrenes; Phenanthrolines; Photosensitizing Agents; Ruthenium

2012
Design, synthesis, and antiviral activity evaluation of phenanthrene-based antofine derivatives.
    Journal of agricultural and food chemistry, 2012, Sep-05, Volume: 60, Issue:35

    Topics: Antiviral Agents; Drug Design; Indoles; Molecular Structure; Phenanthrenes; Phenanthrolines; Ribavirin; RNA, Viral; Structure-Activity Relationship; Tobacco Mosaic Virus

2012
Rhodium(III)-catalyzed intramolecular annulation through C-H activation: total synthesis of (±)-antofine, (±)-septicine, (±)-tylophorine, and rosettacin.
    Angewandte Chemie (International ed. in English), 2012, Sep-10, Volume: 51, Issue:37

    Topics: Alkaloids; Alkynes; Carbon; Catalysis; Cyclization; Heterocyclic Compounds, 4 or More Rings; Hydrogen; Indoles; Indolizines; Isoquinolines; Phenanthrenes; Phenanthrolines; Pyridones; Rhodium; Stereoisomerism

2012
Left, right, or both? On the configuration of the phenanthroindolizidine alkaloid tylophorine from Tylophora indica.
    Journal of natural products, 2013, Feb-22, Volume: 76, Issue:2

    Topics: Alkaloids; Indolizines; Molecular Structure; Phenanthrenes; Phenanthrolines; Tylophora

2013
Air flow-assisted ionization imaging mass spectrometry method for easy whole-body molecular imaging under ambient conditions.
    Analytical chemistry, 2013, Mar-05, Volume: 85, Issue:5

    Topics: Air; Animals; Antineoplastic Agents; Glioma; Indolizines; Male; Mass Spectrometry; Mice; Molecular Imaging; Phenanthrenes; Phenanthrolines; Rats; Rats, Wistar; Whole Body Imaging

2013
c-Jun-mediated anticancer mechanisms of tylophorine.
    Carcinogenesis, 2013, Volume: 34, Issue:6

    Topics: Activating Transcription Factor 1; Alkaloids; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Cyclin A2; Down-Regulation; Elongation Factor 2 Kinase; Eukaryotic Initiation Factors; G1 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Indolizines; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; NF-kappa B; Phenanthrenes; Phenanthrolines; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C-delta; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-jun; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA Interference; RNA, Small Interfering; Transcription Factor AP-1; Tylophora

2013
Conical coils counter-current chromatography for preparative isolation and purification of tanshinones from Salvia miltiorrhiza Bunge.
    Journal of chromatography. A, 2013, May-03, Volume: 1288

    Topics: Abietanes; Chromatography, High Pressure Liquid; Countercurrent Distribution; Drugs, Chinese Herbal; Phenanthrenes; Phenanthrolines; Plant Extracts; Rhizome; Salvia miltiorrhiza

2013
Proapoptotic and TRAIL-sensitizing constituents isolated from Salvia militiorrhiza (Danshen).
    Journal of bioscience and bioengineering, 2013, Volume: 116, Issue:4

    Topics: Abietanes; Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Cell Division; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Humans; Inhibitory Concentration 50; Neoplasms; Phenanthrenes; Phenanthrolines; Plant Extracts; Poly(ADP-ribose) Polymerases; Salvia miltiorrhiza; TNF-Related Apoptosis-Inducing Ligand

2013
Design, synthesis, antiviral activity, and structure-activity relationships (SARs) of two types of structurally novel phenanthroindo/quinolizidine analogues.
    Journal of agricultural and food chemistry, 2014, Feb-12, Volume: 62, Issue:6

    Topics: Antiviral Agents; Drug Design; Indolizidines; Indolizines; Phenanthrenes; Phenanthrolines; Plant Diseases; Quinolizines; Structure-Activity Relationship; Tobacco Mosaic Virus

2014
Experimental studies on amebicidal, antibacterial, and antiparasitic phenanthroline compounds.
    Antibiotics & chemotherapy (Northfield, Ill.), 1958, Volume: 8, Issue:6

    Topics: Amebicides; Anti-Bacterial Agents; Antiparasitic Agents; Phenanthrenes; Phenanthrolines

1958
Collective asymmetric synthesis of (-)-antofine, (-)-cryptopleurine, (-)-tylophorine, and (-)-tylocrebrine with tert-butanesulfinamide as a chiral auxiliary.
    The Journal of organic chemistry, 2014, Apr-18, Volume: 79, Issue:8

    Topics: Alkaloids; Butanes; Indoles; Indolizines; Isomerism; Molecular Structure; Phenanthrenes; Phenanthrolines; Stereoisomerism; Sulfonamides

2014
An enantioselective strategy for the total synthesis of (S)-tylophorine via catalytic asymmetric allylation and a one-pot DMAP-promoted isocyanate formation/Lewis acid catalyzed cyclization sequence.
    Organic & biomolecular chemistry, 2014, Jun-14, Volume: 12, Issue:22

    Topics: Alkaloids; Catalysis; Chemistry, Organic; Cyclization; Indolizines; Isocyanates; Lewis Acids; Phenanthrenes; Phenanthrolines; Pyridines; Stereoisomerism

2014
Short asymmetric synthesis of phenanthroindolizidines through chiral homoallylic sulfinamines.
    Organic & biomolecular chemistry, 2014, Sep-28, Volume: 12, Issue:36

    Topics: Alkaloids; Allyl Compounds; Amines; Indolizines; Molecular Structure; Oxidation-Reduction; Phenanthrenes; Phenanthrolines; Stereoisomerism; Sulfonium Compounds

2014
Photophysical properties of ruthenium(II) polypyridyl DNA intercalators: effects of the molecular surroundings investigated by theory.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, Sep-26, Volume: 20, Issue:40

    Topics: 2,2'-Dipyridyl; DNA; Intercalating Agents; Luminescence; Models, Molecular; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Phenazines; Ruthenium

2014
D and E rings may not be indispensable for antofine: discovery of phenanthrene and alkylamine chain containing antofine derivatives as novel antiviral agents against tobacco mosaic virus (TMV) based on interaction of antofine and TMV RNA.
    Journal of agricultural and food chemistry, 2014, Oct-29, Volume: 62, Issue:43

    Topics: Antiviral Agents; Drug Design; Indoles; Molecular Structure; Phenanthrenes; Phenanthrolines; RNA, Viral; Structure-Activity Relationship; Tobacco Mosaic Virus

2014
Platinum-catalyzed synthesis of substituted phenanthrenes from biphenyl propargyl alcohols via a carbene intermediate.
    Organic letters, 2014, Sep-19, Volume: 16, Issue:18

    Topics: Alkynes; Catalysis; Cyclization; Indoles; Methane; Molecular Structure; Phenanthrenes; Phenanthrolines; Platinum Compounds; Propanols

2014
Design, synthesis, antiviral activity and mode of action of phenanthrene-containing N-heterocyclic compounds inspired by the phenanthroindolizidine alkaloid antofine.
    Pest management science, 2016, Volume: 72, Issue:2

    Topics: Alkaloids; Antiviral Agents; Drug Design; Heterocyclic Compounds; Indoles; Indolizines; Phenanthrenes; Phenanthrolines; Ribavirin; Structure-Activity Relationship; Tobacco Mosaic Virus

2016
Total Synthesis of Phenanthroindolizidine Alkaloids by Combining Iodoaminocyclization with Free Radical Cyclization.
    The Journal of organic chemistry, 2016, 07-15, Volume: 81, Issue:14

    Topics: Alkaloids; Chemistry, Organic; Cyclization; Free Radicals; Indoles; Indolizines; Isoquinolines; Magnetic Resonance Spectroscopy; Phenanthrenes; Phenanthrolines; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship; Temperature

2016
JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits improved transrepression/transactivation dissociation.
    European journal of pharmacology, 2017, May-15, Volume: 803

    Topics: Aminopyridines; Animals; Female; Hepatocytes; Mice; Mice, Inbred BALB C; Phenanthrenes; Phenanthrolines; Receptors, Glucocorticoid; RNA, Messenger; Transcriptional Activation; Tyrosine Transaminase

2017
Synthesis of Bisimidazole Derivatives for Selective Sensing of Fluoride Ion.
    Molecules (Basel, Switzerland), 2017, Sep-11, Volume: 22, Issue:9

    Topics: Benzene Derivatives; Dimethyl Sulfoxide; Fluorides; Imidazoles; Luminescent Measurements; Molecular Structure; Phenanthrenes; Phenanthrolines; Quaternary Ammonium Compounds; Sensitivity and Specificity

2017
Ru(TAP)32+ uses multivalent binding to accelerate and constrain photo-adduct formation on DNA.
    Chemical communications (Cambridge, England), 2019, Jul-23, Volume: 55, Issue:60

    Topics: DNA; DNA Adducts; Guanine; Intercalating Agents; Ligands; Light; Nucleic Acid Conformation; Organometallic Compounds; Phenanthrenes; Phenanthrolines; Ruthenium

2019
Polypyridyl-Based Copper Phenanthrene Complexes: Combining Stability with Enhanced DNA Recognition.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2021, Jan-13, Volume: 27, Issue:3

    Topics: Cell Line, Tumor; Coordination Complexes; Copper; Crystallography, X-Ray; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Humans; Organometallic Compounds; Pancreatic Neoplasms; Phenanthrenes; Phenanthrolines

2021
Design, Synthesis and In-Vitro Biological Evaluation of Antofine and Tylophorine Prodrugs as Hypoxia-Targeted Anticancer Agents.
    Molecules (Basel, Switzerland), 2021, Jun-01, Volume: 26, Issue:11

    Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; CHO Cells; Cricetulus; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Indoles; Indolizines; MCF-7 Cells; Molecular Structure; Phenanthrenes; Phenanthrolines; Prodrugs; Quaternary Ammonium Compounds; Structure-Activity Relationship; Tumor Hypoxia

2021