Page last updated: 2024-08-24

1,7-phenanthroline and neocuproine

1,7-phenanthroline has been researched along with neocuproine in 150 studies

Research

Studies (150)

TimeframeStudies, this research(%)All Research%
pre-199017 (11.33)18.7374
1990's27 (18.00)18.2507
2000's54 (36.00)29.6817
2010's42 (28.00)24.3611
2020's10 (6.67)2.80

Authors

AuthorsStudies
Mantel, MJ; van Riel, LH1
Birnboim, HC1
Antholine, WE; Byrnes, RW; Petering, DH1
Koike, A; Tochikura, T; Tsuji, Y; Yamamoto, K1
Bhat, R; Hadi, SM1
Jacobi, H; Metzger, J; Witte, I1
Mello-Filho, AC; Meneghini, R1
Baker, WL; Panow, A1
Diekert, G; Geerligs, G; Wohlfarth, G1
Asad, NR; Leitão, AC1
Applebaum, YJ; Borman, JB; Chevion, M; Kuvin, J; Uretzky, G1
Takahashi, K; Takita, T; Umezawa, H1
Rodriguez, S; Scheibel, LW1
Baker, WL1
Abraham, A; Abraham, J; Cohenford, MA; Dain, JA1
Abraham, J; Cohenford, MA; Medeiros, AA1
Osisanya, JO1
Løvstad, RA1
Gaisser, HD; Stouthamer, AH; Timmerman, H; van der Goot, H1
Pierson, HF2
Baker, WL; Lowe, T1
Crooke, ST; Huang, CH; Wong, A1
Candido, EP; Hay, CW1
Fisher, JM; Mohindru, A; Rabinovitz, M1
de Bolster, MW; Nauta, WT; Smit, H; Stouthamer, AH; Timmerman, H; van der Goot, H; Vis, RD1
Boni, C; Buzzigoli, G; Giampietro, O; Navalesi, R; Pilo, A1
Demeester, JM; Lauwers, AR; Vercruysse, KP1
Burkitt, MJ1
Buschfort, C; Witte, I1
Dean, RT; Gieseg, SP; Simpson, JA1
Burkitt, MJ; Milne, L; Nicotera, P; Orrenius, S1
Gorren, AC; Mayer, B; Schmidt, K1
Chan, L; Gallagher, J; Kwong, E; Perrin, DM; Sigman, D1
Cavallini, D; Montefoschi, G; Pecci, L1
Al-Sa'doni, HH; Bisland, S; Butler, AR; Flitney, FW; Megson, IL1
Asad, NR; Furtado, FA; Leitão, AC1
Eicke, B; Jacobi, H; Witte, I1
Becker, TW; Jacobi, H; Krieger, G; Vöhringer, ML; Witte, I1
al-Obaid, AM; al-Tamrah, SA; Alwarthan, AA; Aly, FA1
Almeida, CE; Cabral-Neto, JB; Felício, DL; Galhardo, RS; Leitão, AC2
Bouzyk, E; Iwaneńko, T; Kruszewski, M; Szumiel, I1
Gurzenda, EM; Powell, SR; Wapnir, RA; Wingertzahn, MA1
De Man, JG; De Winter, BY; Herman, AG; Moreels, TG; Pelckmans, PA1
Jan, KY; Liu, F1
Chevion, M; Zhu, BZ1
Baysal, F; Dikmen, A; Ertuğ, PU; Göçmen, C; Göktürk, HS; Onder, S1
De Man , JG; De Winter , BY; Herman, AG; Moreels, TG; Pelckmans, PA1
Martin, W; McIntosh, L; Nelli, S1
Karpishin, TB; Vannelli, TA1
Malenkova, IV; Serezhenkov, VA; Vanin, AF1
Gal, S; Lichtenberg, D; Pinchuk, I1
Hu, C; Kitts, DD1
Bashkin, JK; Daniher, AT; Putnam, WC; Trawick, BN1
Ahmad, A; Asad, SF; Hadi, SM; Khan, NU; Singh, S1
Bruchelt, G; Gerber, CE; Greilberger, J; Jürgens, G; Ledinski, G; Niethammer, D1
Currell, DL; Levin, J1
Ast, G; Malca, H; Shomron, N; Vig, I1
Fernandes, A; Filipe, P; Freitas, J; Haigle, J; Mazière, C; Mazière, JC; Morlière, P; Santus, R1
Balasubramanian, S; Gavory, G; Whitney, A1
Nakamura, J; Purvis, ER; Swenberg, JA1
Frei, B; Zhang, WJ1
Guo, L; Liu, G; Liu, S; Wang, L; Zhang, Z1
Feeney, CJ; Gyulkhandanyan, AV; Pennefather, PS1
Ergün, Y; Ogülener, N1
Hormozi Nezhad, MR; Kamali, R; Karimi, MA; Safavi, A; Saghir, N1
Antholine, WE; Cramer, SP; Gerfen, GJ; Gu, W; Krymov, V; Ragsdale, SW; Seravalli, J; Xiao, Y1
Chiosis, G; He, H; Llauger, L; Rosen, N1
Chen, LS; Hsu, CY; Ju, TC; Yang, DI; Yin, JH1
Aitken, MD; Nakamura, J; Swenberg, JA; Zielinska-Park, J1
Chong, CR; Kafsack, BF; Rasoloson, D; Shi, L; Sullivan, DJ1
Leitão, AC; Melo, RG; Pádula, M1
de Groat, WC; Giesselman, B; Göçmen, C1
Apak, R; Güçlü, K; Karademir, SE; Ozyürek, M1
Bergamo, A; Margiotta, N; Natile, G; Papadia, P; Sava, G1
Büyüknacar, HS; Göçmen, C; Kumcu, EK; Onder, S; Singirik, E1
Altun, M; Apak, R; Güçlü, K; Karademir, SE; Ozyürek, M1
Azmi, AS; Bhat, SH; Hadi, SM; Hanif, S2
Alzarban, N; La Du, JK; Tanguay, RL; Tilton, F; Vue, M1
Azmi, AS; Bhat, SH; Hadi, SM1
Bols, NC; Carlson, JC; DeWitte-Orr, SJ; Greenberg, BM; Nykamp, JA; Passaperuma, K; Peters, ZJ1
Ding, CF; Ju, HQ; Li, XM; Zhang, SS1
Apak, R; Bektaşoğlu, B; Güçlü, K; Ozyürek, M2
Safavi, A; Tohidi, M1
Akatov, VS; Soloviev, VV; Solovieva, ME1
Ko, HH; Lin, CN; Lu, YH; Wei, BL1
Chen, SH; Liang, YC; Lin, JK; Lin-Shiau, SY; Liu, SH1
Azmi, AS; Bhat, SH; Hadi, SM; Hanif, S; Shamim, U; Ullah, MF2
Jiang, ZL; Liang, A; Wei, X; Zhang, SS1
Li, H; Liu, T; Wang, Y; Wu, C1
Johnson, SL; O'Reilly-Pol, T1
Büyüknacar, HS; Evrüke, IC; Göçmen, C; Kumcu, EK; Onder, S1
Imura, H; Ishimori, K; Ito, Y; Mori, S; Ohashi, K1
Ahmad, A; Azmi, AS; Hadi, SM; Hanif, S; Kumar, KS; Mohammad, RM; Nazeem, S1
Apak, R; Bener, M; Güçlü, K; Ozyürek, M2
Bi, C; Chen, DI; Cui, Q; Dou, QP; Fan, Y; Xiao, Y; Zhang, X1
Apak, R; Can, Z; Erçağ, E; Eren, S; Kapudan, T; Uzer, A1
Apak, R; Celik, SE; Güçlü, K; Ozyürek, M2
Larhed, M; Lindh, J; Sjöberg, PJ1
Ahmadipour, Z; Kashanian, S; Shahabadi, N1
Guo, LN; Knochel, P; Mayer, P; Thaler, T1
Arnal, N; de Alaniz, MJ; Marra, CA1
Gu, YF; Huang, WP; Shi, ZJ; Sun, CL1
Ahmad, A; Hadi, SM; Khan, HY; Sarkar, FH; Ullah, MF; Zubair, H1
Hou, KP; Lang, JP; Li, HX; Miao, LL; Si, J; Tang, XY; Wang, F; Yu, M; Zheng, AX1
Basaraba, RJ; Bossmann, SH; Harber, GJ; Kutsch, O; Michalek, SM; Niederweis, M; Shrestha, TB; Speer, A; Wolschendorf, F1
Chatterjee, S; Das, O; Paine, TK1
Fu, Y; Huang, Z; Shang, R; Tan, XD; Xiao, X; Zhang, ZR1
Apak, R; Celik, SE; Güçlü, K; Ozyürek, M; Tufan, AN1
Patel, OV; Qin, Z; Wilson, WB1
Apak, R; Avan, AN; Çekiç, SD; Çetinkaya, A1
Czerwieniec, R; Kowalski, K; Yersin, H1
Ahmad, A; Azim, S; Hadi, SM; Khan, HY; Sarkar, FH; Sohail, A; Ullah, MF; Zubair, H1
Bykowska, A; Florek, M; Jeżowska-Bojczuk, M; Król, J; Kyzioł, A; Płotek, M; Starosta, R1
Apak, R; Güçlü, K; Kondakçı, E; Özyürek, M1
Ahmad, A; Faisal, M; Farhan, M; Hadi, SM; Khan, HY; Sarkar, FH; Ullah, MF; Zubair, H1
Kenthirapalan, S; Kooij, TW; Matuschewski, K; Waters, AP1
Abu Ali, H; Abuhijleh, AL; Akkawi, M; Darawsheh, M; Hussein, Y; Jaber, S; Maloul, S; Rappocciolo, E1
Cai, J; Li, SX; Liang, W; Lin, X; Zheng, FY; Zhong, Y1
Apak, R; Baki, S; Güçlü, K; Özyürek, M; Tufan, AN1
Huang, CH; Li, Y; Liu, YX; Mao, L; Zhu, BZ1
Akbarsha, MA; Ganeshpandian, M; Palaniandavar, M; Ramakrishnan, S; Riyasdeen, A; Suresh, E1
Alharrasi, A; Ashraf, GM; Damanhouri, GA; Hadi, SM; Khan, HY; Perveen, A; Tabrez, S1
Paul, BD; Snyder, SH1
Jeżowska-Bojczuk, M; Komarnicka, UK; Kyzioł, A; Starosta, R1
Akyüz, E; Apak, R; Başkan, KS; Özen, S; Tütem, E1
Alfi, N; Khorasani-Motlagh, M; Noroozifar, M1
Arif, H; Hadi, SM; Rehmani, N; Wani, AA; Zafar, A1
Araujo, RGO; Costa, SSL; Dantas, AF; Soares, SAR; Teixeira, LSG1
Fujie, T; Kaji, T; Kawasaki, N; Nakamura, T; Ogata, F; Yamamoto, C; Yoshida, E1
Gaál, A; Ingerle, D; Mihucz, VG; Orgován, G; Pape, I; Streli, C; Szoboszlai, N1
Apak, R; Bener, M; Şen, FB1
Bertuchi, FR; Cerchiaro, G; da Silva, DA; Lago, L; Manieri, TM; Matias, AC; Nunes, EA; Sato, RH1
Apak, R; Avan, AN; Bayarsaikhan, G; Çekiç, SD1
Alvarez, N; Batista, AA; Costa-Filho, AJ; Ellena, J; Facchin, G; Leite, CM; Mendes, LFS; Viña, D1
Harris, HH; Konkankit, CC; Lovett, J; Wilson, JJ1
Białońska, A; de Almeida, RFM; Jezierska, A; Krasowska, A; Panek, JJ; Puchalska, M; Starosta, R; Suchodolski, J; Szmigiel, I1
Damzina, AA; Ermolaev, YE; Gavrilenko, MA; Gavrilenko, NA; Saranchina, NV; Urazov, EV1
Dos Santos, VB; Franco, MOK; Resque, IS; Suarez, WT1
Govindaraju, T; Murugan, NA; Satha, P; Suseela, YV1
Hadwan, MH; Obeid, NJ1
Abrahamovská, M; Klepcová, Z; Mareková, M; Rabajdová, M; Smolko, L; Špaková, I; Urdzík, P1
Chen, G; He, X; Huang, G; Lu, X; Wang, J; Yang, Z; Zhang, Y; Zhang, Z1
Afzal, M; Ahmad, M; Alarifi, A; Muslim, M; Naz, F; Sepay, N1

Reviews

1 review(s) available for 1,7-phenanthroline and neocuproine

ArticleYear
Antimalarial activity of selected aromatic chelators V. Localization of 59Fe in Plasmodium falciparum in the presence of oxines.
    Progress in clinical and biological research, 1989, Volume: 313

    Topics: Animals; Antimalarials; Chelating Agents; Chemical Phenomena; Chemistry; Cinnamates; Copper; Deferoxamine; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Humans; Hydroxyquinolines; In Vitro Techniques; Iron; Metalloproteins; Oxyquinoline; Phenanthrolines; Plasmodium falciparum

1989

Other Studies

149 other study(ies) available for 1,7-phenanthroline and neocuproine

ArticleYear
Interferences in the continuous flow analysis of serum iron by the addition of neocuproine to the acid diluent.
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1977, Volume: 15, Issue:3

    Topics: Autoanalysis; Copper; Diagnostic Errors; Humans; Indicators and Reagents; Iron; Phenanthrolines; Spectrophotometry

1977
Effect of lipophilic chelators on oxyradical-induced DNA strand breaks in human granulocytes: paradoxical effect of 1,10-phenanthroline.
    Archives of biochemistry and biophysics, 1992, Volume: 294, Issue:1

    Topics: 2,2'-Dipyridyl; Chelating Agents; Copper; DNA; DNA Damage; Edetic Acid; Free Radicals; Granulocytes; Humans; Hydrogen Peroxide; Phenanthrolines; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate

1992
Oxidation-reduction reactions in Ehrlich cells treated with copper-neocuproine.
    Free radical biology & medicine, 1992, Volume: 13, Issue:5

    Topics: Animals; Antineoplastic Agents; Biological Transport; Carcinoma, Ehrlich Tumor; Cell Division; Cell Membrane Permeability; Copper; Dimethyl Sulfoxide; DNA Damage; DNA, Neoplasm; Electron Spin Resonance Spectroscopy; Glutathione; Mice; Organometallic Compounds; Oxidation-Reduction; Phenanthrolines; Superoxide Dismutase; Tumor Cells, Cultured

1992
Purification and some properties of L-fucose dehydrogenase from Agrobacterium radiobacter and its application to the assay of bound-fucose in glycoconjugates.
    Biochimica et biophysica acta, 1992, Sep-15, Volume: 1117, Issue:2

    Topics: alpha-L-Fucosidase; Animals; Carbohydrate Dehydrogenases; Copper; Copper Sulfate; Fucose; Glycoconjugates; Hydrogen-Ion Concentration; Molecular Weight; Mucins; NAD; Oxidation-Reduction; Phenanthrolines; Rhizobium; Spectrophotometry; Swine

1992
Photoinduction of strand scissions in DNA by kojic acid: role of transition metal ions and oxygen free radical intermediates in the reaction.
    Mutagenesis, 1992, Volume: 7, Issue:2

    Topics: Animals; Cattle; DNA Damage; Electrophoresis, Agar Gel; Ferrous Compounds; Free Radicals; Kinetics; Light; Metals; Oxygen; Phenanthrolines; Photochemistry; Plasmids; Pyrones

1992
Synergistic effects of Cu(II) and dimethylammonium 2,4-dichlorophenoxyacetate (U46 D fluid) on PM2 DNA and mechanism of DNA damage.
    Free radical research communications, 1992, Volume: 16, Issue:2

    Topics: 2,4-Dichlorophenoxyacetic Acid; Catalase; Copper; Dimethyl Sulfoxide; Dimethylamines; DNA Damage; Drug Synergism; Humans; In Vitro Techniques; Phenanthrolines; Superoxide Dismutase

1992
Iron is the intracellular metal involved in the production of DNA damage by oxygen radicals.
    Mutation research, 1991, Volume: 251, Issue:1

    Topics: 3T3 Cells; Animals; Cell Line, Transformed; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radicals; Iron; Mice; Oxygen; Phenanthrolines

1991
Estimation of cellulase activity using a glucose-oxidase-Cu(II) reducing assay for glucose.
    Journal of biochemical and biophysical methods, 1991, Volume: 23, Issue:4

    Topics: Cellulase; Copper; Glucose; Glucose Oxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Indicators and Reagents; Oxidation-Reduction; Phenanthrolines; Reference Standards; Substrate Specificity

1991
Purification and characterization of NADP(+)-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Peptostreptococcus productus marburg.
    Journal of bacteriology, 1991, Volume: 173, Issue:4

    Topics: Chromatography, Gel; Dose-Response Relationship, Drug; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Hydroxylamine; Hydroxylamines; Mercury; Methylenetetrahydrofolate Dehydrogenase (NADP); NADP; Peptostreptococcus; Phenanthrolines; Phenylhydrazines; Sodium; Spectrum Analysis; Zinc

1991
Effects of metal ion chelators on DNA strand breaks and inactivation produced by hydrogen peroxide in Escherichia coli: detection of iron-independent lesions.
    Journal of bacteriology, 1991, Volume: 173, Issue:8

    Topics: 2,2'-Dipyridyl; Cell Survival; Deferoxamine; DNA; DNA Damage; DNA Repair; Drug Antagonism; Escherichia coli; Hydrogen Peroxide; Iron Chelating Agents; Phenanthrolines

1991
The protective role of neocuproine against cardiac damage in isolated perfused rat hearts.
    Free radical biology & medicine, 1990, Volume: 8, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular Agents; Copper; Copper Sulfate; Coronary Circulation; Coronary Vessels; Heart Function Tests; Hydrogen Peroxide; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Perfusion; Phenanthrolines; Random Allocation; Rats; Rats, Inbred Strains

1990
Effects of o-phenanthroline, 2,2'-dipyridyl and neocuproine on the activities of bleomycin to inhibit DNA synthesis and growth of cultured cells.
    The Journal of antibiotics, 1986, Volume: 39, Issue:10

    Topics: 2,2'-Dipyridyl; Animals; Bleomycin; Cells, Cultured; DNA, Neoplasm; Dose-Response Relationship, Drug; HeLa Cells; Liver Neoplasms, Experimental; Phenanthrolines; Pyridines; Rats

1986
Spectrophotometric determination of penicilloates in penicillins.
    The Analyst, 1989, Volume: 114, Issue:9

    Topics: Copper; Oxidation-Reduction; Penicillanic Acid; Penicillins; Phenanthrolines; Spectrophotometry

1989
Colorimetric assay for free and bound L-fucose.
    Analytical biochemistry, 1989, Feb-15, Volume: 177, Issue:1

    Topics: alpha-L-Fucosidase; Animals; Carbohydrate Dehydrogenases; Chromatography, Paper; Copper; Fucose; Glycosides; Hydrolysis; Mucins; NAD; Oxidation-Reduction; Phenanthrolines; Spectrophotometry; Swine

1989
A colorimetric procedure for measuring beta-lactamase activity.
    Analytical biochemistry, 1988, Feb-01, Volume: 168, Issue:2

    Topics: Anti-Bacterial Agents; beta-Lactamases; Colorimetry; Copper; Copper Sulfate; Penicillanic Acid; Penicillin G; Phenanthrolines

1988
In vitro activity of a substituted phenanthroline on Entamoeba histolytica.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986, Volume: 80, Issue:1

    Topics: Entamoeba histolytica; Phenanthrolines

1986
Interaction of neocuproine, 1,10-phenanthroline and 2,2'-dipyridyl with human ceruloplasmin.
    The International journal of biochemistry, 1988, Volume: 20, Issue:1

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Ceruloplasmin; Chlorpromazine; Humans; Iron Chelating Agents; Kinetics; NAD; Oxidation-Reduction; Phenanthrolines; Protein Binding; Pyridines

1988
Investigation into the mechanism of copper uptake by Mycoplasma gallisepticum in the presence of 2,9-dimethyl-1,10-phenanthroline.
    Pharmaceutisch weekblad. Scientific edition, 1987, Dec-11, Volume: 9, Issue:6

    Topics: Biological Transport; Carrier Proteins; Copper; Membrane Potentials; Mycoplasma; Phenanthrolines; Potassium; Valinomycin

1987
Pharmacological perturbation of murine melanoma growth by copper chelates.
    Cancer letters, 1985, Volume: 26, Issue:2

    Topics: Acetates; Animals; Body Weight; Collagen; Copper; Female; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Nitrilotriacetic Acid; Phenanthrolines; Pigmentation

1985
Sensitive ascorbic acid assay for the analysis of pharmaceutical products and fruit juices.
    The Analyst, 1985, Volume: 110, Issue:10

    Topics: Ascorbic Acid; Beverages; Drug Stability; Fruit; Pharmaceutical Preparations; Phenanthrolines

1985
Enhancement of tumorigenicity of B16 melanoma in heterogenetic mice by administration of copper chelates.
    Cancer treatment reports, 1985, Volume: 69, Issue:11

    Topics: Acetates; Animals; Body Weight; Cocarcinogenesis; Copper; Female; Male; Melanoma; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Nitrilotriacetic Acid; Phenanthrolines; Time Factors

1985
Mechanism of deoxyribonucleic acid breakage induced by 4'-(9-acridinylamino)methanesulfon-m-anisidide and copper: role for cuprous ion and oxygen free radicals.
    Biochemistry, 1984, Jun-19, Volume: 23, Issue:13

    Topics: Aminoacridines; Amsacrine; Anaerobiosis; Copper; DNA; Intercalating Agents; Kinetics; NADP; Oxidation-Reduction; Phenanthrolines; Plasmids; Spectrophotometry; Superoxides

1984
Histone deacetylase from HeLa cells: properties of the high molecular weight complex.
    Biochemistry, 1983, Dec-20, Volume: 22, Issue:26

    Topics: Amidohydrolases; Chromatin; DNA Restriction Enzymes; DNA, Satellite; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Mercaptoethanol; Molecular Weight; Nucleosomes; Phenanthrolines; Protein Conformation

1983
2,9-Dimethyl-1,10-phenanthroline (neocuproine): a potent, copper-dependent cytotoxin with anti-tumor activity.
    Biochemical pharmacology, 1983, Dec-01, Volume: 32, Issue:23

    Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line; Cell Survival; Copper; Leukemia L1210; Leukemia P388; Male; Mice; Phenanthrolines

1983
Mechanism of action of the copper(I) complex of 2,9-dimethyl-1,10-phenanthroline on Mycoplasma gallisepticum.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:6

    Topics: Cell Membrane; Copper; Copper Sulfate; Multienzyme Complexes; Mycoplasma; NADH, NADPH Oxidoreductases; Phenanthrolines; Radioisotopes

1982
Four methods for glucose assay compared for various glucose concentrations and under different clinical conditions.
    Clinical chemistry, 1982, Volume: 28, Issue:12

    Topics: Autoanalysis; Blood Glucose; Diabetes Mellitus; Ferricyanides; Glucose Oxidase; Glucose Tolerance Test; Hexokinase; Humans; Methods; Phenanthrolines; Renal Dialysis; Time Factors; Uremia

1982
Kinetic investigation of the action of hyaluronidase on hyaluronan using the Morgan-Elson and neocuproine assays.
    The Biochemical journal, 1995, Aug-15, Volume: 310 ( Pt 1)

    Topics: Acetylglucosamine; Carbohydrate Sequence; Chelating Agents; Hyaluronic Acid; Hyaluronoglucosaminidase; Kinetics; Molecular Sequence Data; Phenanthrolines; Reproducibility of Results

1995
Copper--DNA adducts.
    Methods in enzymology, 1994, Volume: 234

    Topics: Copper; DNA; DNA Adducts; DNA Damage; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Indicators and Reagents; Iron; Kinetics; Oxidation-Reduction; Phenanthrolines

1994
Induction and mechanism of DNA single- and double-strand breaks by tetracycline/Cu(II) in the absence of light.
    Carcinogenesis, 1994, Volume: 15, Issue:12

    Topics: Bacteriophages; Catalase; Chelating Agents; Copper; Darkness; DNA; DNA Damage; DNA Repair; DNA, Single-Stranded; DNA, Viral; Drug Synergism; Phenanthrolines; Reactive Oxygen Species; Tetracycline

1994
Free radical and enzymatic mechanisms for the generation of protein bound reducing moieties.
    Biochimica et biophysica acta, 1993, Feb-13, Volume: 1156, Issue:2

    Topics: Amidines; Copper; Copper Sulfate; Cytochrome c Group; Dihydroxyphenylalanine; Ferric Compounds; Free Radicals; Gamma Rays; Monophenol Monooxygenase; Oxidation-Reduction; Phenanthrolines; Proteins; Pulse Radiolysis; Serum Albumin, Bovine; Tyrosine; Ultraviolet Rays

1993
1,10-Phenanthroline stimulates internucleosomal DNA fragmentation in isolated rat-liver nuclei by promoting the redox activity of endogenous copper ions.
    The Biochemical journal, 1996, Jan-01, Volume: 313 ( Pt 1)

    Topics: Animals; Apoptosis; Calcium; Cell Nucleus; Chelating Agents; Copper; DNA; DNA Damage; Endonucleases; Enzyme Activation; Hydroxyl Radical; Intercalating Agents; Iron Chelating Agents; Liver; Magnesium; Male; Nucleosomes; Oxidation-Reduction; Phenanthrolines; Rats; Rats, Sprague-Dawley; Stimulation, Chemical

1996
Decomposition of S-nitrosoglutathione in the presence of copper ions and glutathione.
    Archives of biochemistry and biophysics, 1996, Jun-15, Volume: 330, Issue:2

    Topics: Aerobiosis; Anaerobiosis; Animals; Chelating Agents; Copper; Cuprizone; Free Radicals; Glutathione; Glutathione Disulfide; Humans; In Vitro Techniques; Kinetics; Metals; Nitric Oxide; Nitroso Compounds; Oxidation-Reduction; Phenanthrolines; S-Nitrosoglutathione; Spectrophotometry

1996
Recognition of tetrahedral 1,10-phenanthroline-cuprous chelates by transcriptionally active complexes does not depend on the sequence of the promoter.
    Chemistry & biology, 1996, Volume: 3, Issue:9

    Topics: Chelating Agents; Copper; DNA Damage; DNA Footprinting; DNA-Directed RNA Polymerases; DNA, Single-Stranded; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen Peroxide; Iron Chelating Agents; Lac Operon; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenanthrolines; Promoter Regions, Genetic; Transcription, Genetic

1996
Some new details of the copper-hydrogen peroxide interaction.
    Biochemical and biophysical research communications, 1997, Jun-09, Volume: 235, Issue:1

    Topics: Catalase; Copper; Hydrogen Peroxide; Hydroxyl Radical; Oxidation-Reduction; Oxygen; Phenanthrolines; Polarography; Reactive Oxygen Species; Spectrophotometry

1997
Neocuproine, a selective Cu(I) chelator, and the relaxation of rat vascular smooth muscle by S-nitrosothiols.
    British journal of pharmacology, 1997, Volume: 121, Issue:6

    Topics: Animals; Chelating Agents; Copper; Glutathione; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroso Compounds; Penicillamine; Phenanthrolines; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Vasodilator Agents

1997
Effects of 1,10-phenanthroline and hydrogen peroxide in Escherichia coli: lethal interaction.
    Mutation research, 1997, Volume: 385, Issue:3

    Topics: 2,2'-Dipyridyl; Benzoates; Benzoic Acid; Chelating Agents; Copper; Deferoxamine; Escherichia coli; Ethanol; Exodeoxyribonucleases; Ferric Compounds; Ferrous Compounds; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Intercalating Agents; Iron; Oxidants; Phenanthrolines; Thiourea

1997
DNA strand break induction and enhanced cytotoxicity of propyl gallate in the presence of copper(II).
    Free radical biology & medicine, 1998, Volume: 24, Issue:6

    Topics: Catalase; Cell Line; Copper; Corticoviridae; DNA Damage; DNA Fragmentation; Drug Synergism; Fibroblasts; Humans; Hydrogen Peroxide; Phenanthrolines; Propyl Gallate; Reactive Oxygen Species

1998
Synergistic DNA damaging effects of malondialdehyde/Cu(II) in PM2 DNA and in human fibroblasts.
    Toxicology letters, 1998, Volume: 94, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents; Bacteriophages; Cell Survival; Cells, Cultured; Chelating Agents; Copper; Dimethyl Sulfoxide; DNA Damage; DNA, Single-Stranded; DNA, Viral; Drug Synergism; Fibroblasts; Humans; Malondialdehyde; Phenanthrolines

1998
Determination of (S)(-)-cathinone by spectrophotometric detection.
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:2

    Topics: Alkaloids; Buffers; Central Nervous System Stimulants; Copper; Drug Stability; Phenanthrolines; Plant Extracts; Plant Leaves; Psychotropic Drugs; Spectrophotometry

1998
Synergistic lethal effect between hydrogen peroxide and neocuproine (2,9-dimethyl 1,10-phenanthroline) in Escherichia coli.
    Mutation research, 1999, Jan-26, Volume: 433, Issue:1

    Topics: 2,2'-Dipyridyl; Bacterial Proteins; Centrifugation, Density Gradient; Chelating Agents; DNA; DNA Damage; DNA Repair; Drug Synergism; Escherichia coli; Hydrogen Peroxide; Iron; Mutation; Phenanthrolines; Recombination, Genetic; SOS Response, Genetics

1999
Chelating of iron and copper alters properties of DNA in L5178Y cells, as revealed by the comet assay.
    Mutation research, 1999, May-14, Volume: 434, Issue:1

    Topics: Animals; Cell Count; Cell Nucleus; Cell Survival; Chelating Agents; Copper; Deferoxamine; DNA Damage; DNA, Neoplasm; Electrophoresis, Agar Gel; Iron; Leukemia L5178; Micronuclei, Chromosome-Defective; Micronucleus Tests; Phenanthrolines; Tumor Cells, Cultured

1999
Promotion of copper excretion from the isolated rat heart attenuates postischemic cardiac oxidative injury.
    The American journal of physiology, 1999, Volume: 277, Issue:3

    Topics: Animals; Antidotes; Chelating Agents; Copper; Deferoxamine; Histidine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Organometallic Compounds; Oxidative Stress; Phenanthrolines; Rats; Rats, Sprague-Dawley

1999
Neocuproine potentiates the activity of the nitrergic neurotransmitter but inhibits that of S-nitrosothiols.
    European journal of pharmacology, 1999, Sep-24, Volume: 381, Issue:2-3

    Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Chelating Agents; Cuprizone; Electric Stimulation; Gastric Fundus; Isometric Contraction; Male; Monoamine Oxidase Inhibitors; Muscle, Smooth; Neurotransmitter Agents; Nitrates; Nitric Oxide; Phenanthrolines; Rats; Rats, Wistar; Sulfhydryl Compounds

1999
DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells.
    Free radical biology & medicine, 2000, Jan-01, Volume: 28, Issue:1

    Topics: Amitrole; Animals; Antioxidants; Aorta; Arsenites; Bacterial Proteins; Cadmium Chloride; Catalase; Cattle; Cells, Cultured; Chromans; Citrulline; Ditiocarb; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Endothelium, Vascular; Enzyme Inhibitors; Escherichia coli Proteins; Free Radical Scavengers; Hydrogen Peroxide; Molsidomine; Mutagens; N-Glycosyl Hydrolases; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Onium Compounds; Phenanthrolines; Reactive Oxygen Species; Sodium Compounds; Sodium Selenite; Superoxide Dismutase; Superoxides; Thiomalates; Thiourea; Uric Acid

2000
Copper ions mediate the lethality induced by hydrogen peroxide in low iron conditions in Escherichia coli.
    Mutation research, 2000, Jun-30, Volume: 460, Issue:1

    Topics: 2,2'-Dipyridyl; Adenosine Triphosphatases; Bacterial Proteins; Cell Division; Centrifugation, Density Gradient; Chelating Agents; Copper; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA-Formamidopyrimidine Glycosylase; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Hydrogen Peroxide; Iron; Iron Deficiencies; Mutagenesis; Mutagens; N-Glycosyl Hydrolases; Phenanthrolines

2000
Copper-mediated toxicity of 2,4,5-trichlorophenol: biphasic effect of the copper(I)-specific chelator neocuproine.
    Archives of biochemistry and biophysics, 2000, Aug-15, Volume: 380, Issue:2

    Topics: Catalase; Chelating Agents; Chlorophenols; Copper; Dimethyl Sulfoxide; Drug Interactions; Escherichia coli; Ethanol; Free Radical Scavengers; Oxidation-Reduction; Phenanthrolines; Superoxide Dismutase

2000
Effect of neocuproine, a selective Cu(I) chelator, on nitrergic relaxations in the mouse corpus cavernosum.
    European journal of pharmacology, 2000, Oct-13, Volume: 406, Issue:2

    Topics: Acetylcholine; Animals; Chelating Agents; Copper; Dose-Response Relationship, Drug; Electric Stimulation; Glutathione; Male; Mice; Nitric Oxide; Nitroprusside; Nitroso Compounds; Penis; Phenanthrolines; Phenylephrine; S-Nitrosoglutathione

2000
Pre- and postjunctional protective effect of neocuproine on the nitrergic neurotransmitter in the mouse gastric fundus.
    British journal of pharmacology, 2001, Volume: 132, Issue:1

    Topics: Animals; Antioxidants; Chelating Agents; Copper; Dinoprost; Electric Stimulation; Gastric Fundus; In Vitro Techniques; Isometric Contraction; Male; Mice; Muscle Relaxation; Muscle, Smooth; Neuromuscular Junction; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Donors; Oxidants; Phenanthrolines; Superoxide Dismutase

2001
Role of copper ions and cytochrome P450 in the vasodilator actions of the nitroxyl anion generator, Angeli's salt, on rat aorta.
    European journal of pharmacology, 2001, Feb-02, Volume: 412, Issue:3

    Topics: Animals; Aorta; Chelating Agents; Chlorides; Copper Sulfate; Cuprizone; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Edetic Acid; Estradiol; Free Radical Scavengers; In Vitro Techniques; Male; Manganese Compounds; Nitric Oxide Donors; Nitrites; Oxidation-Reduction; Penicillamine; Phenanthrolines; Proadifen; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sodium Azide; Superoxide Dismutase; Vasodilation

2001
Neocuproine-extended porphyrin coordination complexes. 2. Spectroscopic properties of the metalloporphyrin derivatives and investigations into the HOMO ordering.
    Inorganic chemistry, 2000, Jan-24, Volume: 39, Issue:2

    Topics: Antineoplastic Agents; Magnetic Resonance Spectroscopy; Metalloporphyrins; Phenanthrolines; Solvents

2000
Nitric oxide initiates iron binding to neocuproine.
    Nitric oxide : biology and chemistry, 2001, Volume: 5, Issue:2

    Topics: Chelating Agents; Cysteine; Electron Spin Resonance Spectroscopy; Iron; Iron Chelating Agents; Kinetics; Nitric Oxide; Nitrogen Oxides; Nitroso Compounds; Phenanthrolines; S-Nitrosothiols; Spectrophotometry, Ultraviolet; Temperature

2001
The dose-dependent effect of copper-chelating agents on the kinetics of peroxidation of low-density lipoprotein (LDL).
    Free radical research, 2001, Volume: 34, Issue:4

    Topics: Chelating Agents; Copper; Dose-Response Relationship, Drug; Free Radical Scavengers; Free Radicals; Humans; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Phenanthrolines

2001
Evaluation of antioxidant activity of epigallocatechin gallate in biphasic model systems in vitro.
    Molecular and cellular biochemistry, 2001, Volume: 218, Issue:1-2

    Topics: 2,2'-Dipyridyl; Amidines; Antioxidants; Catechin; Chelating Agents; Chromans; Copper; Humans; In Vitro Techniques; Indicators and Reagents; Lipid Peroxidation; Lipoproteins, LDL; Models, Biological; Oxidants; Oxidation-Reduction; Phenanthrolines; Phosphatidylcholines; Reference Values; Vitamin E

2001
Efficient new ribozyme mimics: direct mapping of molecular design principles from small molecules to macromolecular, biomimetic catalysts.
    Nucleic acids research, 2001, May-15, Volume: 29, Issue:10

    Topics: Base Sequence; Catalysis; Cations, Divalent; Copper; Dimerization; Drug Design; Kinetics; Ligands; Molecular Mimicry; Molecular Structure; Phenanthrolines; Pyridines; RNA; RNA Probes; RNA, Catalytic; Structure-Activity Relationship; Substrate Specificity

2001
Oxidative DNA damage by capsaicin and dihydrocapsaicin in the presence of Cu(II).
    Cancer letters, 2001, Aug-28, Volume: 169, Issue:2

    Topics: Animals; Capsaicin; Cattle; Copper; DNA; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; Models, Chemical; Oxidative Stress; Oxygen; Phenanthrolines; Plasmids; Protein Binding; Thymus Gland; Time Factors

2001
Low-density lipoprotein modification by normal, myeloperoxidase-deficient and NADPH oxidase-deficient granulocytes and the impact of redox active transition metal ions.
    Redox report : communications in free radical research, 2002, Volume: 7, Issue:2

    Topics: Adult; Deferoxamine; Edetic Acid; Female; Granulocytes; Humans; Lipoproteins, LDL; Male; NADPH Oxidases; Oxidation-Reduction; Pentetic Acid; Peroxidase; Phenanthrolines; Reference Values

2002
The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide.
    European journal of biochemistry, 2002, Volume: 269, Issue:18

    Topics: Edetic Acid; Escherichia coli; Hemoglobins; Hydrogen-Ion Concentration; Lipopolysaccharides; Oxidation-Reduction; Phenanthrolines; Salmonella; Structure-Activity Relationship

2002
Reversible inhibition of the second step of splicing suggests a possible role of zinc in the second step of splicing.
    Nucleic acids research, 2002, Oct-01, Volume: 30, Issue:19

    Topics: Chelating Agents; Copper; Dose-Response Relationship, Drug; HeLa Cells; Humans; Phenanthrolines; RNA Splicing; RNA, Messenger; RNA, Small Nuclear; Spliceosomes; Zinc

2002
Anti- and pro-oxidant effects of urate in copper-induced low-density lipoprotein oxidation.
    European journal of biochemistry, 2002, Volume: 269, Issue:22

    Topics: Animals; Antioxidants; Carotenoids; Cattle; Copper; Edetic Acid; Kidney; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Liver; Malondialdehyde; Models, Chemical; Oxidants; Oxygen; Phenanthrolines; Superoxide Dismutase; Time Factors

2002
Site-specific cleavage of human telomerase RNA using PNA-neocuproine.Zn(II) derivatives.
    Chemical communications (Cambridge, England), 2003, Jan-07, Issue:1

    Topics: Binding Sites; Electrophoresis, Polyacrylamide Gel; Humans; Peptide Nucleic Acids; Phenanthrolines; RNA; RNA, Long Noncoding; RNA, Untranslated; Telomerase; Zinc

2003
Micromolar concentrations of hydrogen peroxide induce oxidative DNA lesions more efficiently than millimolar concentrations in mammalian cells.
    Nucleic acids research, 2003, Mar-15, Volume: 31, Issue:6

    Topics: 2,2'-Dipyridyl; Apurinic Acid; Cell Survival; Chelating Agents; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; HeLa Cells; Humans; Hydrogen Peroxide; Oxidative Stress; Phenanthrolines

2003
Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells.
    Free radical biology & medicine, 2003, Mar-15, Volume: 34, Issue:6

    Topics: Blotting, Northern; Cell Survival; Chelating Agents; Copper; Deferoxamine; DNA Primers; DNA-Binding Proteins; Dose-Response Relationship, Drug; E-Selectin; Electrophoretic Mobility Shift Assay; Endothelium, Vascular; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Interferon Regulatory Factor-1; Iron; NF-kappa B; Nitric Oxide Synthase; Phenanthrolines; Phosphoproteins; RNA, Messenger; Sp1 Transcription Factor; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2003
[Study on color reaction of copper(II)-neocuprine-glutathione-alcohol system].
    Guang pu xue yu guang pu fen xi = Guang pu, 2000, Volume: 20, Issue:3

    Topics: Antineoplastic Agents; Copper; Ethanol; Glutathione; Glycine max; Phenanthrolines; Plant Extracts; Spectrophotometry, Atomic

2000
Modulation of mitochondrial membrane potential and reactive oxygen species production by copper in astrocytes.
    Journal of neurochemistry, 2003, Volume: 87, Issue:2

    Topics: Animals; Antioxidants; Astrocytes; Cells, Cultured; Chelating Agents; Copper; Hydrogen Peroxide; Membrane Potentials; Mitochondria; Oxidants; Oxidation-Reduction; Phenanthrolines; Rats; Rats, Wistar; Reactive Oxygen Species; Uncoupling Agents

2003
Neocuproine inhibits the decomposition of endogenous S-nitrosothiol by ultraviolet irradiation in the mouse gastric fundus.
    European journal of pharmacology, 2004, Feb-06, Volume: 485, Issue:1-3

    Topics: Animals; Dose-Response Relationship, Drug; Female; Gastric Fundus; In Vitro Techniques; Male; Mice; Muscle Relaxation; Phenanthrolines; S-Nitrosothiols; Ultraviolet Rays

2004
Sensitive indirect spectrophotometric determination of isoniazid.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2004, Volume: 60, Issue:4

    Topics: Antitubercular Agents; Copper; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Ions; Isoniazid; Models, Chemical; Phenanthrolines; Sensitivity and Specificity; Spectrophotometry; Time Factors

2004
Evidence that NiNi acetyl-CoA synthase is active and that the CuNi enzyme is not.
    Biochemistry, 2004, Apr-06, Volume: 43, Issue:13

    Topics: Acetate-CoA Ligase; Aldehyde Oxidoreductases; Chelating Agents; Clostridium; Copper; Electron Spin Resonance Spectroscopy; Enzyme Activation; Multienzyme Complexes; Nickel; Phenanthrolines; Spectrum Analysis; X-Rays

2004
General method for the synthesis of 8-arylsulfanyl adenine derivatives.
    The Journal of organic chemistry, 2004, Apr-30, Volume: 69, Issue:9

    Topics: Adenine; Hydrocarbons, Iodinated; Molecular Structure; Phenanthrolines; Sulfur Compounds

2004
Nitric oxide and BCNU chemoresistance in C6 glioma cells: role of S-nitrosoglutathione.
    Free radical biology & medicine, 2004, May-15, Volume: 36, Issue:10

    Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Antioxidants; Carbamates; Carmustine; Chelating Agents; Drug Resistance, Neoplasm; Glioma; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenanthrolines; Rats; S-Nitrosoglutathione; Tumor Cells, Cultured

2004
Aldehydic DNA lesions in calf thymus DNA and HeLa S3 cells produced by bacterial quinone metabolites of fluoranthene and pyrene.
    Carcinogenesis, 2004, Volume: 25, Issue:9

    Topics: Aldehydes; Antineoplastic Agents; Cell Membrane; Cell Survival; Copper; DNA; DNA Damage; Fluorenes; Glutathione; HeLa Cells; Humans; Hydrogen Peroxide; Mitochondria; Mutagenicity Tests; Oxidants; Oxidative Stress; Phenanthrolines; Pyrenes; Reactive Oxygen Species

2004
Copper pathways in Plasmodium falciparum infected erythrocytes indicate an efflux role for the copper P-ATPase.
    The Biochemical journal, 2004, Aug-01, Volume: 381, Issue:Pt 3

    Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Arabidopsis Proteins; Caenorhabditis elegans Proteins; Cation Transport Proteins; Chelating Agents; Chromosome Mapping; Copper; DNA, Protozoan; Drosophila Proteins; Erythrocyte Membrane; Erythrocytes; Humans; Mice; Molecular Sequence Data; Open Reading Frames; Phenanthrolines; Plasmodium falciparum; Protozoan Proteins; Saccharomyces cerevisiae Proteins; Sequence Analysis, Protein; Superoxide Dismutase

2004
Role of OGG1 and NTG2 in the repair of oxidative DNA damage and mutagenesis induced by hydrogen peroxide in Saccharomyces cerevisiae: relationships with transition metals iron and copper.
    Yeast (Chichester, England), 2004, Volume: 21, Issue:12

    Topics: 2,2'-Dipyridyl; Chelating Agents; Copper; DNA Damage; DNA Glycosylases; DNA Repair; Genetic Complementation Test; Hydrogen Peroxide; Iron; Mutagenesis; Phenanthrolines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2004
Effect of neocuproine, a copper(i) chelator, on rat bladder function.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:3

    Topics: Adenosine Triphosphate; Animals; Chelating Agents; Copper; Electric Stimulation; Female; In Vitro Techniques; Muscle Contraction; Nitric Oxide; Phenanthrolines; Rats; Rats, Sprague-Dawley; Suramin; Urinary Bladder

2005
Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method.
    Journal of agricultural and food chemistry, 2004, Dec-29, Volume: 52, Issue:26

    Topics: Antioxidants; Ascorbic Acid; Chelating Agents; Copper; Diet; Flavonoids; Oxidation-Reduction; Phenanthrolines; Phenols; Polyphenols; Vitamin E

2004
Platinum(II) complexes with antitumoral/antiviral aromatic heterocycles: effect of glutathione upon in vitro cell growth inhibition.
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: Acyclovir; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Glutathione; Guanine; Mice; Organoplatinum Compounds; Phenanthrolines

2005
Neocuproine, a copper (I) chelator, potentiates purinergic component of vas deferens contractions elicited by electrical field stimulation.
    Pharmacology, 2005, Volume: 75, Issue:2

    Topics: Adenosine Triphosphate; Animals; Chelating Agents; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Nitric Oxide; Phenanthrolines; Prazosin; Rats; Rats, Wistar; Receptors, Purinergic; Suramin; Vas Deferens

2005
Total antioxidant capacity assay of human serum using copper(II)-neocuproine as chromogenic oxidant: the CUPRAC method.
    Free radical research, 2005, Volume: 39, Issue:9

    Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; beta Carotene; Bilirubin; Chromogenic Compounds; Glutathione; Humans; In Vitro Techniques; Phenanthrolines; Serum; Spectrophotometry; Uric Acid

2005
Plant polyphenols mobilize endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for anticancer properties.
    FEBS letters, 2006, Jan-23, Volume: 580, Issue:2

    Topics: Antineoplastic Agents; Antioxidants; Chelating Agents; Comet Assay; Copper; DNA Damage; Flavonoids; Gallic Acid; Humans; Lymphocytes; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Phenols; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances

2006
Dithiocarbamates have a common toxic effect on zebrafish body axis formation.
    Toxicology and applied pharmacology, 2006, Oct-01, Volume: 216, Issue:1

    Topics: Aminobenzoates; Analysis of Variance; Animals; Body Patterning; Carbon Disulfide; Chelating Agents; Collagen Type II; Copper; Dimethyldithiocarbamate; Disulfiram; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Fetal Proteins; Gene Expression Regulation, Developmental; In Situ Hybridization; Isothiocyanates; Molecular Structure; Notochord; Phenanthrolines; Pyrrolidines; T-Box Domain Proteins; Thiocarbamates; Toxicity Tests; Zebrafish; Zebrafish Proteins

2006
Ascorbic acid mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for anticancer properties.
    The international journal of biochemistry & cell biology, 2006, Volume: 38, Issue:12

    Topics: Antineoplastic Agents; Antioxidants; Ascorbic Acid; Comet Assay; Copper; DNA Damage; Drug Screening Assays, Antitumor; Free Radical Scavengers; Humans; Hydrogen Peroxide; Lymphocytes; Neoplasms; Oxidants; Oxidation-Reduction; Phenanthrolines; Tannins

2006
Prooxidant DNA breakage induced by caffeic acid in human peripheral lymphocytes: involvement of endogenous copper and a putative mechanism for anticancer properties.
    Toxicology and applied pharmacology, 2007, Feb-01, Volume: 218, Issue:3

    Topics: Antineoplastic Agents; Antioxidants; Caffeic Acids; Chelating Agents; Comet Assay; Copper; Coumaric Acids; DNA; DNA Breaks; DNA Damage; Dose-Response Relationship, Drug; Drug Combinations; Free Radical Scavengers; Gallic Acid; Humans; Lymphocytes; Oxidative Stress; Phenanthrolines; Propionates; Thiobarbituric Acid Reactive Substances

2007
Effect of copper on the cytotoxicity of phenanthrene and 9,10-phenanthrenequinone to the human placental cell line, JEG-3.
    Reproductive toxicology (Elmsford, N.Y.), 2007, Volume: 23, Issue:4

    Topics: Anthracenes; Anthraquinones; Cell Line, Tumor; Cell Survival; Chelating Agents; Copper; Dose-Response Relationship, Drug; Drug Synergism; Energy Metabolism; Environmental Pollutants; Humans; Oxidation-Reduction; Oxidative Stress; Phenanthrenes; Phenanthrolines; Placenta; Reactive Oxygen Species; Trophoblasts

2007
Nucleic acid biosensor for detection of hepatitis B virus using 2,9-dimethyl-1,10-phenanthroline copper complex as electrochemical indicator.
    Analytica chimica acta, 2007, Jan-16, Volume: 582, Issue:1

    Topics: Biosensing Techniques; Copper; DNA, Viral; Electrochemistry; Hepatitis B virus; Molecular Structure; Nucleic Acid Hybridization; Phenanthrolines; Sensitivity and Specificity

2007
Spectrophotometric determination of ascorbic acid by the modified CUPRAC method with extractive separation of flavonoids-La(III) complexes.
    Analytica chimica acta, 2007, Apr-04, Volume: 588, Issue:1

    Topics: Acetates; Ascorbic Acid; Beverages; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Copper; Flavonoids; Food Analysis; Hydrogen-Ion Concentration; Hydrolysis; Lanthanum; Phenanthrolines; Solvents; Spectrophotometry; Tablets

2007
Simultaneous kinetic determination of levodopa and carbidopa by H-point standard addition method.
    Journal of pharmaceutical and biomedical analysis, 2007, May-09, Volume: 44, Issue:1

    Topics: Antiparkinson Agents; Carbidopa; Ethanol; Excipients; Hydrogen-Ion Concentration; Kinetics; Levodopa; Osmolar Concentration; Oxidation-Reduction; Pharmaceutical Preparations; Phenanthrolines; Sensitivity and Specificity; Solubility; Spectrophotometry; Surface-Active Agents; Tablets; Temperature

2007
Vitamin B12b increases the cytotoxicity of short-time exposure to ascorbic acid, inducing oxidative burst and iron-dependent DNA damage.
    European journal of pharmacology, 2007, Jul-02, Volume: 566, Issue:1-3

    Topics: Antioxidants; Apoptosis; Ascorbic Acid; Cell Line, Tumor; Cell Survival; Deferoxamine; DNA Breaks, Single-Stranded; Humans; Hydrogen Peroxide; Hydroxocobalamin; Iron; Iron Chelating Agents; Oxidative Stress; Phenanthrolines; Respiratory Burst; Vitamins

2007
DNA strand-scission by phloroglucinols and lignans from heartwood of Garcinia subelliptica Merr. and Justicia plants.
    Phytochemistry, 2008, Volume: 69, Issue:1

    Topics: Acanthaceae; Copper; DNA Cleavage; DNA Damage; DNA, Circular; DNA, Superhelical; Electrophoresis, Agar Gel; Garcinia; Lignans; Magnetic Resonance Spectroscopy; Phenanthrolines; Phloroglucinol; Reactive Oxygen Species; Spectrophotometry, Infrared; Wood

2008
Apoptosis of cultured astrocytes induced by the copper and neocuproine complex through oxidative stress and JNK activation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 102, Issue:1

    Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Caspase 3; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Chelating Agents; Copper; Cytochromes c; DNA Breaks; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Glutathione; Inhibitory Concentration 50; Membrane Potential, Mitochondrial; Mitochondria; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenanthrolines; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Time Factors

2008
Hydroxyl radical scavenging assay of phenolics and flavonoids with a modified cupric reducing antioxidant capacity (CUPRAC) method using catalase for hydrogen peroxide degradation.
    Analytica chimica acta, 2008, Jun-02, Volume: 616, Issue:2

    Topics: Antioxidants; Catalase; Chromatography, High Pressure Liquid; Copper; Edetic Acid; Flavonoids; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kinetics; Molecular Structure; Oxidation-Reduction; Phenanthrolines; Phenols; Reproducibility of Results; Salicylates; Sensitivity and Specificity; Time Factors

2008
The anthocyanidin delphinidin mobilizes endogenous copper ions from human lymphocytes leading to oxidative degradation of cellular DNA.
    Toxicology, 2008, Jul-10, Volume: 249, Issue:1

    Topics: Anthocyanins; Cells, Cultured; Comet Assay; Copper; DNA Breaks; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Lymphocytes; Lythraceae; Oxidants; Oxidative Stress; Phenanthrolines; Reactive Oxygen Species

2008
A selective resonance scattering assay for immunoglobulin G using Cu(II)-ascorbic acid-immunonanogold reaction.
    Analytical biochemistry, 2008, Sep-15, Volume: 380, Issue:2

    Topics: Ascorbic Acid; Catalysis; Cations, Divalent; Copper; Copper Sulfate; Fluorometry; Gold; Humans; Immunoglobulin G; Immunohistochemistry; Magnetic Resonance Spectroscopy; Metal Nanoparticles; Oxidation-Reduction; Phenanthrolines

2008
A strategy for direct identification of protein S-nitrosylation sites by quadrupole time-of-flight mass spectrometry.
    Journal of the American Society for Mass Spectrometry, 2008, Volume: 19, Issue:9

    Topics: Amyloid beta-Peptides; Binding Sites; Chelating Agents; Edetic Acid; Humans; Insulin; Microchemistry; Nitroso Compounds; Peptide Fragments; Peptides; Phenanthrolines; S-Nitrosoglutathione; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2008
Plant polyphenols mobilize nuclear copper in human peripheral lymphocytes leading to oxidatively generated DNA breakage: implications for an anticancer mechanism.
    Free radical research, 2008, Volume: 42, Issue:8

    Topics: Antineoplastic Agents; Catechin; Cell Nucleus; Cell Survival; Cells, Cultured; Comet Assay; DNA Breaks; Flavonoids; Humans; Hydrogen Peroxide; Lymphocytes; Oxidants; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Phenols; Plant Extracts; Polyphenols

2008
Neocuproine ablates melanocytes in adult zebrafish.
    Zebrafish, 2008, Volume: 5, Issue:4

    Topics: Animals; Animals, Genetically Modified; Chelating Agents; Copper; Green Fluorescent Proteins; Melanins; Melanocytes; Phenanthrolines; Skin Pigmentation; Tumor Suppressor Protein p53; Zebrafish

2008
Differential effect of neocuproine, a copper(I) chelator, on contractile activity in isolated ovariectomized non-pregnant rat, pregnant rat and pregnant human uterus.
    European journal of pharmacology, 2009, Mar-01, Volume: 605, Issue:1-3

    Topics: Animals; Chelating Agents; Copper; Dose-Response Relationship, Drug; Female; Gestational Age; Humans; Myometrium; Ovariectomy; Oxytocin; Phenanthrolines; Pregnancy; Rats; Rats, Wistar; Receptors, Purinergic; Uterine Contraction

2009
Equilibrium and ab initio computational studies on the adduct formation of 1,3-diketonato-lithium(I), -sodium(I) and -potassium(I) with 1,10-phenanthroline and its 2,9-dimethyl derivatives.
    Talanta, 2009, Jun-15, Volume: 78, Issue:4-5

    Topics: Amines; Chelating Agents; Lithium; Phenanthrolines; Potassium; Sodium; Thermodynamics

2009
Plumbagin induces cell death through a copper-redox cycle mechanism in human cancer cells.
    Mutagenesis, 2009, Volume: 24, Issue:5

    Topics: Cell Death; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Shape; Comet Assay; Copper; Cytoprotection; Free Radical Scavengers; Humans; Naphthoquinones; Neoplasms; Oxidation-Reduction; Phenanthrolines; Skin Neoplasms

2009
Development of a low-cost optical sensor for cupric reducing antioxidant capacity measurement of food extracts.
    Analytical chemistry, 2010, May-15, Volume: 82, Issue:10

    Topics: Antioxidants; Ascorbic Acid; Beverages; Copper; Flavonoids; Food; Indicators and Reagents; Optical Devices; Oxidation-Reduction; Phenanthrolines

2010
Molecular study on copper-mediated tumor proteasome inhibition and cell death.
    International journal of oncology, 2010, Volume: 37, Issue:1

    Topics: Breast Neoplasms; Cell Death; Chelating Agents; Copper; Dose-Response Relationship, Drug; Humans; Jurkat Cells; Leukemia; Neoplasms; Phenanthrolines; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured

2010
Determination of peroxide-based explosives with copper(II)-neocuproine assay combined with a molecular spectroscopic sensor.
    The Analyst, 2010, Volume: 135, Issue:8

    Topics: Bridged Bicyclo Compounds, Heterocyclic; Colorimetry; Copper; Heterocyclic Compounds, 1-Ring; Peroxides; Phenanthrolines; Spectrophotometry

2010
Determination of antioxidants by a novel on-line HPLC-cupric reducing antioxidant capacity (CUPRAC) assay with post-column detection.
    Analytica chimica acta, 2010, Jul-26, Volume: 674, Issue:1

    Topics: Antioxidants; Camellia sinensis; Chromatography, High Pressure Liquid; Copper; Flavonoids; Indicators and Reagents; Mentha; Origanum; Oxidation-Reduction; Phenanthrolines; Phenols; Plant Extracts; Polyphenols

2010
Synthesis of aryl ketones by palladium(II)-catalyzed decarboxylative addition of benzoic acids to nitriles.
    Angewandte Chemie (International ed. in English), 2010, Oct-11, Volume: 49, Issue:42

    Topics: Acetonitriles; Benzoates; Catalysis; Decarboxylation; Hydroxybenzoate Ethers; Ketones; Ligands; Microwaves; Molecular Structure; Palladium; Phenanthrolines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2010
DNA binding and gel electrophoresis studies of a new silver(I) complex containing 2,9-dimethyl-1,10-phenanthroline ligands.
    DNA and cell biology, 2011, Volume: 30, Issue:3

    Topics: Animals; Binding, Competitive; Cattle; DNA; Kinetics; Molecular Structure; Organometallic Compounds; Phenanthrolines; Silver; Spectrometry, Fluorescence; Thermodynamics; Viscosity

2011
Highly diastereoselective C(sp3)-C(sp) cross-coupling reactions between 1,3- and 1,4-substituted cyclohexylzinc reagents and bromoalkynes through remote stereocontrol.
    Angewandte Chemie (International ed. in English), 2011, Feb-25, Volume: 50, Issue:9

    Topics: Alkynes; Catalysis; Cyclohexanes; Palladium; Phenanthrolines; Quantum Theory; Stereoisomerism

2011
Carnosine and neocuproine as neutralizing agents for copper overload-induced damages in cultured human cells.
    Chemico-biological interactions, 2011, Jul-15, Volume: 192, Issue:3

    Topics: Carnosine; Cell Line, Tumor; Chelating Agents; Copper; Environmental Pollutants; Humans; Phenanthrolines; Protein Carbonylation; Thiobarbituric Acid Reactive Substances

2011
Neocuproine-KOtBu promoted intramolecular cross coupling to approach fused rings.
    Chemical communications (Cambridge, England), 2011, Sep-21, Volume: 47, Issue:35

    Topics: Butanols; Hydrocarbons, Aromatic; Phenanthrolines

2011
The prooxidant action of dietary antioxidants leading to cellular DNA breakage and anticancer effects: implications for chemotherapeutic action against cancer.
    Cell biochemistry and biophysics, 2013, Volume: 67, Issue:2

    Topics: Antineoplastic Agents; Antioxidants; Cell Death; Cell Nucleus; Cell Proliferation; Copper; Diet; DNA Breaks; Drug Interactions; Electron Transport; Humans; Isoflavones; Lymphocytes; MCF-7 Cells; Oxidative Stress; Phenanthrolines; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Thiourea

2013
Differences in responsivity of original cupric reducing antioxidant capacity and cupric-bathocuproine sulfonate assays to antioxidant compounds.
    Analytical biochemistry, 2012, Apr-01, Volume: 423, Issue:1

    Topics: Antioxidants; beta Carotene; Chelating Agents; Copper; Humans; Oxidation-Reduction; Phenanthrolines; Spectrophotometry, Ultraviolet

2012
Reactions of the cationic zinc thiolate model complex [Zn(Tab)4](PF6)2 with N-donor ligands and cobalt dichloride.
    Inorganic chemistry, 2012, Oct-01, Volume: 51, Issue:19

    Topics: 2,2'-Dipyridyl; Cobalt; Coordination Complexes; Crystallography, X-Ray; Imidazoles; Ligands; Models, Molecular; Phenanthrolines; Pyridines; Sulfhydryl Compounds; Zinc

2012
Copper-boosting compounds: a novel concept for antimycobacterial drug discovery.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Antitubercular Agents; Copper; Drug Design; High-Throughput Screening Assays; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenanthrolines; Trace Elements; Tuberculosis; Virulence Factors

2013
Functional models of α-keto acid dependent nonheme iron oxygenases: synthesis and reactivity of biomimetic iron(II) benzoylformate complexes supported by a 2,9-dimethyl-1,10-phenanthroline ligand.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2013, Volume: 18, Issue:3

    Topics: Biomimetic Materials; Coordination Complexes; Crystallography, X-Ray; Ferrous Compounds; Glyoxylates; Keto Acids; Ligands; Mandelic Acids; Models, Molecular; Oxygen; Oxygenases; Phenanthrolines

2013
Copper-catalyzed decarboxylative coupling of alkynyl carboxylates with 1,1-dibromo-1-alkenes.
    The Journal of organic chemistry, 2013, May-03, Volume: 78, Issue:9

    Topics: Alkenes; Alkynes; Carboxylic Acids; Chemistry Techniques, Synthetic; Copper; Decarboxylation; Hydrocarbons, Brominated; Molecular Structure; Organometallic Compounds; Phenanthrolines

2013
Direct measurement of total antioxidant capacity of cereals: QUENCHER-CUPRAC method.
    Talanta, 2013, Apr-15, Volume: 108

    Topics: Antioxidants; Copper; Edible Grain; Food Analysis; Phenanthrolines; Phenols

2013
Production of LPS-induced inflammatory mediators in murine peritoneal macrophages: neocuproine as a broad inhibitor and ATP7A as a selective regulator.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2013, Volume: 26, Issue:3

    Topics: Adenosine Triphosphatases; Animals; Cation Transport Proteins; Copper-Transporting ATPases; Female; Inflammation Mediators; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Phenanthrolines

2013
Correlation of total antioxidant capacity with reactive oxygen species (ROS) consumption measured by oxidative conversion.
    Journal of agricultural and food chemistry, 2013, Jun-05, Volume: 61, Issue:22

    Topics: Antioxidants; Chelating Agents; Chromans; Food Analysis; Free Radical Scavengers; Indicators and Reagents; Kinetics; Models, Chemical; Oxidation-Reduction; Phenanthrolines; Phenylenediamines; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances

2013
Highly efficient thermally activated fluorescence of a new rigid Cu(I) complex [Cu(dmp)(phanephos)]+.
    Dalton transactions (Cambridge, England : 2003), 2013, Jul-21, Volume: 42, Issue:27

    Topics: Copper; Fluorescence; Molecular Structure; Organometallic Compounds; Phenanthrolines; Phosphines; Polycyclic Compounds; Temperature

2013
Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants.
    Cell death & disease, 2013, Jun-06, Volume: 4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Chelating Agents; Copper; DNA; DNA Breaks, Double-Stranded; Drug Screening Assays, Antitumor; Free Radical Scavengers; Humans; Lymphocytes; Oxidation-Reduction; Phenanthrolines; Plasmids; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Thiourea

2013
Copper(I) (pseudo)halide complexes with neocuproine and aminomethylphosphines derived from morpholine and thiomorpholine - in vitro cytotoxic and antimicrobial activity and the interactions with DNA and serum albumins.
    Chemical biology & drug design, 2013, Volume: 82, Issue:5

    Topics: Animals; Anti-Infective Agents; Candida albicans; Cattle; Cell Line, Tumor; Cell Survival; Coordination Complexes; Copper; DNA; Humans; Mice; Microbial Sensitivity Tests; Morpholines; Phenanthrolines; Phosphines; Serum Albumin; Staphylococcus aureus

2013
Novel optical fiber reflectometric CUPRAC sensor for total antioxidant capacity measurement of food extracts and biological samples.
    Journal of agricultural and food chemistry, 2013, Sep-04, Volume: 61, Issue:35

    Topics: Animals; Antioxidants; Beverages; Chromans; Copper; Food Analysis; Fruit; Kidney; Liver; Mice; Optical Fibers; Phenanthrolines; Reproducibility of Results; Spectrum Analysis

2013
Novel pro-oxidant activity assay for polyphenols, vitamins C and E using a modified CUPRAC method.
    Talanta, 2013, Oct-15, Volume: 115

    Topics: Acetates; Antioxidants; Ascorbic Acid; Biological Assay; Calibration; Cations, Divalent; Cations, Monovalent; Copper; Egg Proteins; Oxidation-Reduction; Phenanthrolines; Plant Extracts; Polyphenols; Protein Carbonylation; Sensitivity and Specificity; Solutions; Sulfhydryl Compounds; Vitamin E

2013
Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer chemopreventive action.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:3

    Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apigenin; Apoptosis; Catechin; Cell Death; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Copper; Drug Screening Assays, Antitumor; Humans; Luteolin; Phenanthrolines; Polyphenols; Reactive Oxygen Species; Resveratrol; Stilbenes

2014
Copper-transporting ATPase is important for malaria parasite fertility.
    Molecular microbiology, 2014, Volume: 91, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Cation Transport Proteins; Copper; Copper-Transporting ATPases; Culicidae; Disease Models, Animal; Female; Fertility; Malaria; Male; Mice; Mice, Inbred C57BL; Mutation; Phenanthrolines; Plasmodium berghei; Protozoan Proteins

2014
New mixed ligand zinc(II) complexes based on the antiepileptic drug sodium valproate and bioactive nitrogen-donor ligands. Synthesis, structure and biological properties.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Aminopyridines; Anti-Bacterial Agents; Anticonvulsants; Antimalarials; Bacteria; Crystallography, X-Ray; Dose-Response Relationship, Drug; Hemeproteins; Ligands; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Organometallic Compounds; Phenanthrolines; Picolines; Quinolines; Structure-Activity Relationship; Valproic Acid; Zinc

2014
Constituting fully integrated visual analysis system for Cu(II) on TiO₂/cellulose paper.
    Analytical chemistry, 2014, Jul-15, Volume: 86, Issue:14

    Topics: Adsorption; Artifacts; Calibration; Cellulose; Chemistry Techniques, Analytical; China; Color; Colorimetry; Copper; Drinking Water; Humic Substances; Hydrogen-Ion Concentration; Hydroxylamine; Image Processing, Computer-Assisted; Limit of Detection; Paper; Phenanthrolines; Photochemical Processes; Photolysis; Seawater; Software; Titanium; Water Pollutants, Chemical

2014
A novel differential pulse voltammetric (DPV) method for measuring the antioxidant capacity of polyphenols-reducing cupric neocuproine complex.
    Journal of agricultural and food chemistry, 2014, Jul-23, Volume: 62, Issue:29

    Topics: Antioxidants; Copper; Electrochemical Techniques; Phenanthrolines; Polyphenols

2014
Detoxifying polyhalogenated catechols through a copper-chelating agent by forming stable and redox-inactive hydrogen-bonded complexes with an unusual perpendicular structure.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, Sep-26, Volume: 20, Issue:40

    Topics: Catechols; Chelating Agents; Coordination Complexes; Copper; Halogenation; Hydrogen Bonding; Models, Molecular; Oxidation-Reduction; Phenanthrolines

2014
Mixed ligand copper(II) complexes of 2,9-dimethyl-1,10-phenanthroline: tridentate 3N primary ligands determine DNA binding and cleavage and cytotoxicity.
    Journal of inorganic biochemistry, 2014, Volume: 140

    Topics: Binding Sites; Cell Cycle; Cell Survival; Copper; Crystallography, X-Ray; DNA; Drug Screening Assays, Antitumor; Humans; Ligands; MCF-7 Cells; Phenanthrolines; Spectrometry, Mass, Electrospray Ionization

2014
Pro-oxidant DNA breakage induced by the interaction of L-DOPA with Cu(II): a putative mechanism of neurotoxicity.
    Advances in experimental medicine and biology, 2015, Volume: 822

    Topics: Antiparkinson Agents; Chelating Agents; Comet Assay; Copper; DNA Breaks; Humans; Hydroxyl Radical; Levodopa; Lymphocytes; Neurotoxicity Syndromes; Oxidation-Reduction; Phenanthrolines; Reactive Oxygen Species; Superoxides

2015
Protein sulfhydration.
    Methods in enzymology, 2015, Volume: 555

    Topics: Biotin; Cell Line; Cysteine; Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+); Humans; Hydrogen Sulfide; Maleimides; Morpholines; Organothiophosphorus Compounds; Oxidation-Reduction; Phenanthrolines; Protein Processing, Post-Translational; Signal Transduction; Staining and Labeling; Streptavidin; Sulfides

2015
Copper(i) complexes with phosphine derived from sparfloxacin. Part I - structures, spectroscopic properties and cytotoxicity.
    Dalton transactions (Cambridge, England : 2003), 2015, Jul-28, Volume: 44, Issue:28

    Topics: Animals; Cell Line, Tumor; Cell Survival; Coordination Complexes; Copper; Crystallography, X-Ray; Fluoroquinolones; Humans; Iodides; Ligands; Magnetic Resonance Spectroscopy; Mice; Phenanthrolines; Phosphines; Quinolines; Spectrophotometry, Ultraviolet; Thiocyanates

2015
Spectrophotometric total reducing sugars assay based on cupric reduction.
    Talanta, 2016, Jan-15, Volume: 147

    Topics: Carbohydrates; Copper; Fruit and Vegetable Juices; Hydrogen-Ion Concentration; Hydrolysis; Oxidation-Reduction; Phenanthrolines; Reducing Agents; Spectrophotometry; Sucrose

2016
Evaluation DNA-/BSA-binding properties of a new europium complex containing 2,9-dimethyl-1,10-phenanthroline.
    Journal of biomolecular structure & dynamics, 2017, Volume: 35, Issue:7

    Topics: DNA; DNA-Binding Proteins; Europium; Fluorescence; Molecular Structure; Phenanthrolines; Protein Binding; Serum Albumin, Bovine

2017
Copper-mediated DNA damage by the neurotransmitter dopamine and L-DOPA: A pro-oxidant mechanism.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 40

    Topics: Cell Line; Cell Line, Tumor; Chelating Agents; Copper; DNA Damage; Dopamine; Dopamine Agents; Humans; Levodopa; Lymphocytes; Oxidation-Reduction; Phenanthrolines; Reactive Oxygen Species

2017
Comparison of Spectrophotometric Methods for the Determination of Copper in Sugar Cane Spirit.
    Journal of AOAC International, 2018, May-01, Volume: 101, Issue:3

    Topics: Brazil; Calibration; Chelating Agents; Coordination Complexes; Copper; Cuprizone; Hydrogen-Ion Concentration; Hydroxylamine; Indicators and Reagents; Ligands; Limit of Detection; Oxidation-Reduction; Phenanthrolines; Saccharum; Spectrophotometry

2018
Synergistic cytotoxicity caused by forming a complex of copper and 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:6

    Topics: Animals; Cattle; Cells, Cultured; Coordination Complexes; Copper; Drug Synergism; Endothelial Cells; Hydrophobic and Hydrophilic Interactions; Ligands; Organometallic Compounds; Phenanthrolines

2017
Metal transport capabilities of anticancer copper chelators.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2018, Volume: 47

    Topics: Antineoplastic Agents; Cell Line, Tumor; Chelating Agents; Copper; Dithizone; Humans; Metals; Oxyquinoline; Phenanthrolines; Thiosemicarbazones; Zinc

2018
Heparin-stabilized gold nanoparticles-based CUPRAC colorimetric sensor for antioxidant capacity measurement.
    Talanta, 2018, Sep-01, Volume: 187

    Topics: Antioxidants; Colorimetry; Copper; Fruit and Vegetable Juices; Gold; Heparin; Hydrogen-Ion Concentration; Metal Nanoparticles; Oxidation-Reduction; Particle Size; Phenanthrolines; Plant Extracts; Surface Properties

2018
Protective effects of neocuproine copper chelator against oxidative damage in NSC34 cells.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2018, Volume: 836, Issue:Pt B

    Topics: Chelating Agents; Copper; Copper-Transporting ATPases; DNA Damage; Humans; Hydrogen Peroxide; Neuroblastoma; Oxidants; Oxidative Stress; Phenanthrolines; Protective Agents; Reactive Oxygen Species; Tumor Cells, Cultured

2018
Use of modified CUPRAC and dinitrophenylhydrazine colorimetric methods for simultaneous measurement of oxidative protein damage and antioxidant defense against oxidation.
    Talanta, 2019, Nov-01, Volume: 204

    Topics: Animals; Antioxidants; Blood Proteins; Cattle; Citrus sinensis; Colorimetry; Copper; Egg Proteins; Fruit and Vegetable Juices; Hydrazines; Phenanthrolines; Poultry; Protein Carbonylation; Serum Albumin, Bovine

2019
Synthesis and structural characterization of a series of ternary copper(II)-L-dipeptide-neocuproine complexes. Study of their cytotoxicity against cancer cells including MDA-MB-231, triple negative breast cancer cells.
    Journal of inorganic biochemistry, 2020, Volume: 203

    Topics: A549 Cells; Antineoplastic Agents; Cell Proliferation; Chelating Agents; Coordination Complexes; Copper; Dipeptides; DNA; Humans; MCF-7 Cells; Phenanthrolines; Triple Negative Breast Neoplasms

2020
X-Ray fluorescence microscopy reveals that rhenium(i) tricarbonyl isonitrile complexes remain intact in vitro.
    Chemical communications (Cambridge, England), 2020, Jun-16, Volume: 56, Issue:48

    Topics: Antineoplastic Agents; Coordination Complexes; Endoplasmic Reticulum Stress; HeLa Cells; Humans; Phenanthrolines; Rhenium; Spectrometry, X-Ray Emission

2020
New anticandidal Cu(i) complexes with neocuproine and ketoconazole derived diphenyl(aminomethyl)phosphane: luminescence properties for detection in fungal cells.
    Dalton transactions (Cambridge, England : 2003), 2020, Jul-07, Volume: 49, Issue:25

    Topics: Adult; Antifungal Agents; Candida albicans; Cell Survival; Cells, Cultured; Coordination Complexes; Copper; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Ketoconazole; Luminescent Measurements; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Optical Imaging; Phenanthrolines; Phosphines

2020
Determination of antioxidant capacity of medicinal tinctures using cuprac method involving Cu(II) neocuproine immobilized into polymethacrylate matrix.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Oct-15, Volume: 240

    Topics: Antioxidants; Copper; Oxidation-Reduction; Phenanthrolines; Polymethacrylic Acids

2020
A novel digital image method for determination of reducing sugars in aged and non-aged cachaças employing a smartphone.
    Food chemistry, 2021, Feb-15, Volume: 338

    Topics: Alcoholic Beverages; Colorimetry; Copper; Equipment Design; Food Analysis; Food Contamination; Fructose; Glucose; Phenanthrolines; Saccharum; Smartphone; Sugars

2021
Recognition of G-quadruplex topology through hybrid binding with implications in cancer theranostics.
    Theranostics, 2020, Volume: 10, Issue:23

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carbazoles; Cell Line, Tumor; DNA Damage; Female; G-Quadruplexes; HEK293 Cells; Humans; Intravital Microscopy; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Dynamics Simulation; Neoplasms; Oxidative Stress; Phenanthrolines; Precision Medicine; Proto-Oncogene Proteins c-bcl-2; Pyridinium Compounds; Spheroids, Cellular; Theranostic Nanomedicine; Xenograft Model Antitumor Assays

2020
A quantitative method for the assessment of homocysteine thiolactonase enzyme activity.
    Analytical biochemistry, 2021, 10-15, Volume: 631

    Topics: Copper; HEPES; Homocysteine; Humans; Phenanthrolines; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2021
Zinc(II) niflumato complex effects on MMP activity and gene expression in human endometrial cell lines.
    Scientific reports, 2021, 09-27, Volume: 11, Issue:1

    Topics: Cell Line; Cell Survival; Drug Evaluation, Preclinical; Endometriosis; Endometrium; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Matrix Metalloproteinases; Organometallic Compounds; Phenanthrolines; Zinc

2021
Hydrazine Hydrate Accelerates Neocuproine-Copper Complex Generation and Utilization in Alkyne Reduction, a Significant Supplement Method for Catalytic Hydrogenation.
    The Journal of organic chemistry, 2021, 12-17, Volume: 86, Issue:24

    Topics: Alkynes; Copper; Hydrazines; Hydrogenation; Phenanthrolines

2021
Structural, Theoretical Investigations, Hirshfeld Surface Analysis, and Cytotoxicity Profile of a Neocuproine-Co(II)-Based Discrete Homodinuclear Complex.
    Applied biochemistry and biotechnology, 2023, Volume: 195, Issue:2

    Topics: Cell Line; Crystallography, X-Ray; Molecular Docking Simulation; Phenanthrolines

2023