Compounds > 1,7-dimethylxanthine

1,7-dimethylxanthine and tizanidine

1,7-dimethylxanthine has been researched along with tizanidine in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Backman, JT; Granfors, MT; Laitila, J; Neuvonen, PJ1
Backman, JT; Neuvonen, PJ; Schröder, MT1

Trials

2 trial(s) available for 1,7-dimethylxanthine and tizanidine

ArticleYear
Oral contraceptives containing ethinyl estradiol and gestodene markedly increase plasma concentrations and effects of tizanidine by inhibiting cytochrome P450 1A2.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:4

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Area Under Curve; Caffeine; Clonidine; Contraceptives, Oral, Combined; Cytochrome P-450 CYP1A2 Inhibitors; Drug Synergism; Ethinyl Estradiol; Female; Half-Life; Humans; Norpregnenes; Theophylline

2005
Effects of gender and moderate smoking on the pharmacokinetics and effects of the CYP1A2 substrate tizanidine.
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Area Under Curve; Blood Pressure; Body Weight; Caffeine; Clonidine; Cytochrome P-450 CYP1A2; Drug Interactions; Female; Half-Life; Humans; Male; Sex Factors; Sleep Stages; Smoking; Theophylline

2008