1,6-dinitropyrene has been researched along with 1,8-dinitropyrene in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (45.65) | 18.7374 |
| 1990's | 16 (34.78) | 18.2507 |
| 2000's | 9 (19.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Debnath, AK; Debnath, G; Hansch, C; Lopez de Compadre, RL; Shusterman, AJ | 1 |
| Hajos, AK; Shane, BS; Traynor, CA; Winston, GW | 1 |
| Imaida, K; King, CM; Lee, MS; Wang, CY | 1 |
| Doskocil, G; Ghayourmanesh, S; Heisig, V; Hsieh, LL; Jeffrey, AM; Santella, RM; Wong, D | 1 |
| Hajos, AK; Winston, GW | 1 |
| Ishidate, M; Sawada, M; Sofuni, T | 1 |
| Combes, RD; Rowland, IR; Shah, AB | 1 |
| Guengerich, FP; Shimada, T | 1 |
| Beland, FA; Djuríc, Z; Fifer, EK | 1 |
| Horikawa, K; Izumi, K; Maeda, T; Nakagawa, R; Otofuji, T; Otsuka, H; Sano, N; Tokiwa, H | 1 |
| King, CM | 1 |
| Beland, FA; Djurić, Z; Heflich, RH; Potter, DW | 1 |
| Beland, FA; Djurić, Z; Fifer, EK; Heflich, RH; Howard, PC | 1 |
| Aune, T; Deilhaug, T; Haugen, A | 1 |
| Ishizaka, Y; Nagao, M; Ochiai, M; Ohgaki, H; Sato, S; Sugimura, T; Tahira, T; Takayama, S | 1 |
| Imaida, K; King, CM; Lee, MS; Tay, LK; Wang, CY | 1 |
| Adachi, S; Katayama, H; Matsushita, H; Odagiri, Y; Takemoto, K | 1 |
| Anders, M; McCoy, EC; Mermelstein, R; Rosenkranz, HS | 1 |
| Horikawa, K; Nakagawa, R; Tokiwa, H | 1 |
| Hasegawa, H; Kato, T; Negishi, C; Ohgaki, H; Sato, S; Sugimura, T | 1 |
| Brooker, PC; Edgar, DH | 1 |
| Horikawa, K; Kitamori, S; Nakagawa, R; Nakashima, K; Tokiwa, H | 1 |
| Horikawa, K; Kitamori, S; Matamala, L; Nakagawa, R; Tokiwa, H | 1 |
| Katoh, Y; Shudo, K; Takayama, S | 1 |
| Dutcher, JS; Li, AP | 1 |
| Nesnow, S; Slaga, TJ; Triplett, LL | 1 |
| Parry, JM; Wilcox, P | 1 |
| Danford, N; Parry, JM; Wilcox, P | 2 |
| Hayakawa, K; Kawaguchi, Y; Miyazaki, M; Murahashi, T | 1 |
| Katoh, Y; Maekawa, M; Sano, Y | 1 |
| Bian, SS; Lee, H; Lin, TL; Shieh, RL | 1 |
| Bertoli, C; Carere, A; Conti, L; Crebelli, R; Crochi, B; Del Giacomo, N | 1 |
| Beland, FA; Neft, RE; Roe, AL; Smith, BA | 1 |
| Gonzáez de Mejía, E; Loarca-Piña, G; Quintanar-Hernández, A | 1 |
| Hirayama, T; Ishida, S; Kasai, T; Minami, H; Ogawa, S; Wakabayashi, K; Watanabe, T | 1 |
| Furuta, A; Hirayama, T; Ishida, S; Kasai, T; Kishiji, M; Takahashi, Y; Wakabayashi, K; Watanabe, T | 1 |
| Asanoma, M; Endo, O; Goto, S; Hirayama, T; Matsumoto, Y; Sakai, S; Sera, N; Takahashi, Y; Wakabayashi, K; Watanabe, T | 1 |
| Basu, AK; Purohit, V | 1 |
| Guengerich, FP; Hatanaka, N; Hayakawa, K; Kizu, R; Nakajima, M; Shimada, N; Yamazaki, H; Yokoi, T | 1 |
| Alenin, VV; Borkhsenius, AS; Forafonov, FS; Inge-Vechtomov, SG; Kulikov, VN; Tikhodeev, ON | 1 |
| Hayashi, M; Honma, M; Kohara, A; Ohwada, T; Oomori, T; Suzuki, T | 1 |
| Basu, AK; Broyde, S; Hilario, P; Hingerty, BE; Yan, S | 1 |
| Hasei, T; Hirayama, T; Murahashi, T; Otake, S; Takahashi, Y; Takamura, T; Wakabayashi, K; Watanabe, T | 1 |
| Arlt, VM; Asare, N; Gorria, M; Holme, JA; Lagadic-Gossmann, D; Landvik, NE; Solhaug, A | 1 |
| Asanoma, M; Hasei, T; Hirayama, T; Hoshino, Y; Konishi, E; Takahashi, K; Wakabayashi, K; Watanabe, T | 1 |
1 review(s) available for 1,6-dinitropyrene and 1,8-dinitropyrene
| Article | Year |
|---|---|
Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity.
Topics: Animals; Chemical Phenomena; Chemistry; Mutagenicity Tests; Mutagens; Nitro Compounds; Structure-Activity Relationship | 1991 |
45 other study(ies) available for 1,6-dinitropyrene and 1,8-dinitropyrene
| Article | Year |
|---|---|
Modulation of the mutagenicity of three dinitropyrene isomers in vitro by rat-liver S9, cytosolic, and microsomal fractions following chronic ethanol ingestion.
Topics: Alcoholic Intoxication; Animals; Antimutagenic Agents; Cytosol; Enzyme Activation; Inactivation, Metabolic; Liver Extracts; Male; Microsomes, Liver; Mutagenesis; Mutagenicity Tests; Mutagens; Nitroreductases; Pyrenes; Quinone Reductases; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1992 |
Carcinogenicity of dinitropyrenes in the weanling female CD rat.
Topics: Adenocarcinoma; Adenofibroma; Animals; Carcinogens; Female; Histiocytoma, Benign Fibrous; Leukemia, Experimental; Mammary Neoplasms, Experimental; Pyrenes; Rats; Rats, Inbred Strains | 1991 |
Metabolic activation of nitropyrenes and diesel particulate extracts.
Topics: Animals; Cattle; DNA; DNA Damage; Female; Fuel Oils; Humans; Male; Mice; Mutagenicity Tests; Mutagens; Nitro Compounds; Pyrenes; Rabbits; Rats; Vehicle Emissions | 1990 |
Purified NAD(P)H-quinone oxidoreductase enhances the mutagenicity of dinitropyrenes in vitro.
Topics: Animals; Drug Synergism; In Vitro Techniques; Liver; Mutagenicity Tests; Mutagens; NAD(P)H Dehydrogenase (Quinone); Pyrenes; Rats | 1991 |
Decreased clastogenicity of dinitropyrenes in Chinese hamster lung (CHL) subclone cells with low NADPH-cytochrome P-450 reductase activity.
Topics: Animals; Biotransformation; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Drug Resistance; Lung; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; NADPH-Ferrihemoprotein Reductase; Pyrenes; Vitamin K | 1991 |
Inhibition of dinitropyrene mutagenicity in vitro and in vivo using Salmonella typhimurium and the intrasanguinous host-mediated assay.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Female; Inactivation, Metabolic; Injections, Intravenous; Liver; Mice; Mice, Inbred BALB C; Microsomes, Liver; Mutagenicity Tests; Mutagens; Pyrenes; Salmonella typhimurium | 1991 |
Inactivation of 1,3-, 1,6-, and 1,8-dinitropyrene by cytochrome P-450 enzymes in human and rat liver microsomes.
Topics: Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Immunologic Techniques; In Vitro Techniques; Inactivation, Metabolic; Microsomes, Liver; Mixed Function Oxygenases; Mutagens; Pyrenes; Rabbits; Rats; Substrate Specificity | 1990 |
Acetyl coenzyme A-dependent binding of carcinogenic and mutagenic dinitropyrenes to DNA.
Topics: Acetyl Coenzyme A; Animals; Carcinogens, Environmental; Cytosol; DNA; Dogs; In Vitro Techniques; Liver; Male; Mutagens; Pyrenes; Rats; Rats, Inbred F344; Vehicle Emissions | 1985 |
Dinitro derivatives of pyrene and fluoranthene in diesel emission particulates and their tumorigenicity in mice and rats.
Topics: Animals; DNA Damage; Electron Probe Microanalysis; Fluorenes; Male; Mice; Mice, Inbred BALB C; Mutagens; Neoplasms, Experimental; Pyrenes; Rats; Rats, Inbred F344; Vehicle Emissions | 1986 |
Metabolism and biological effects of nitropyrene and related compounds.
Topics: Animals; Carcinogenicity Tests; Female; Histiocytoma, Benign Fibrous; Leukemia; Mammary Neoplasms, Animal; Pyrenes; Rats | 1988 |
Aerobic and anaerobic reduction of nitrated pyrenes in vitro.
Topics: Animals; Cytochrome c Group; Cytosol; Humans; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Pyrenes; Rats; Salmonella typhimurium | 1986 |
Synthesis and mutagenicity of 1-nitro-6-nitrosopyrene and 1-nitro-8-nitrosopyrene, potential intermediates in the metabolic activation of 1,6- and 1,8-dinitropyrene.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Female; Indicators and Reagents; Mutagenicity Tests; Mutagens; Mutation; Nitroso Compounds; Ovary; Pyrenes; Salmonella typhimurium; Structure-Activity Relationship | 1986 |
Nitropyrene-induced DNA repair in Clara cells and alveolar type-II cells isolated from rabbit lung.
Topics: Animals; DNA Repair; Dose-Response Relationship, Drug; Lung; Male; Pyrenes; Rabbits | 1986 |
Carcinogenicity of dinitropyrenes in rats and hamsters.
Topics: Animals; Cricetinae; Female; Male; Mesocricetus; Mutagens; Neoplasms, Experimental; Oncogenes; Pyrenes; Rats; Rats, Inbred F344 | 1986 |
Mechanisms of tumor induction by dinitropyrenes in the female CD rat.
Topics: Animals; Cells, Cultured; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mutagens; Neoplasms, Experimental; Oxidation-Reduction; Pyrenes; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Carcinogenic effects of a mixture of nitropyrenes in F344 rats following its repeated oral administrations.
Topics: Administration, Oral; Animals; Body Weight; Clitoris; Female; Leukemia, Experimental; Mammary Neoplasms, Experimental; Mutagens; Neoplasms, Experimental; Organ Size; Pyrenes; Rats; Rats, Inbred F344; Vulvar Neoplasms | 1986 |
Mutagenicity of nitropyrenes for Escherichia coli: requirement for increased cellular permeability.
Topics: Cell Membrane Permeability; Escherichia coli; Mutagenicity Tests; Mutagens; Plasmids; Pyrenes | 1985 |
Mutagenic/carcinogenic agents in indoor pollutants; the dinitropyrenes generated by kerosene heaters and fuel gas and liquefied petroleum gas burners.
Topics: Air Pollutants; Carcinogens; Chromatography, Gas; Chromatography, High Pressure Liquid; Fossil Fuels; Microclimate; Mutagenicity Tests; Mutagens; Mutation; Pyrenes; Salmonella typhimurium | 1985 |
Absence of carcinogenicity of 1-nitropyrene, correction of previous results, and new demonstration of carcinogenicity of 1,6-dinitropyrene in rats.
Topics: Animals; Dose-Response Relationship, Drug; Male; Mutagens; Neoplasms, Experimental; Pyrenes; Rats; Rats, Inbred F344; Time Factors | 1985 |
Induction of 6-thioguanine resistance, chromosome aberrations and SCE by dinitropyrenes in Chinese hamster ovary cells in vitro.
Topics: Animals; Cell Line; Cell Survival; Chromosome Aberrations; Cricetinae; Cricetulus; Drug Resistance; Female; Fibroblasts; Hypoxanthine Phosphoribosyltransferase; Mutagenicity Tests; Ovary; Pyrenes; Sister Chromatid Exchange; Thioguanine | 1985 |
Identification of dinitropyrenes in diesel-exhaust particles. Their probable presence as the major mutagens.
Topics: Chromatography, High Pressure Liquid; Fuel Oils; Microscopy, Electron, Scanning; Mutagenicity Tests; Mutagens; Mutation; Petroleum; Pyrenes; Salmonella typhimurium; Structure-Activity Relationship; Vehicle Emissions | 1983 |
Demonstration of a powerful mutagenic dinitropyrene in airborne particulate matter.
Topics: Air Pollutants; Air Pollutants, Occupational; Animals; Cell Line; Chile; Chromatography, High Pressure Liquid; Chromosome Aberrations; Mutagenicity Tests; Mutagens; Mutation; Pyrenes; Rats; Salmonella typhimurium; Species Specificity; Structure-Activity Relationship | 1983 |
Inhibition by hemin of dinitropyrene-induced mutagenesis in Chinese hamster V79 cells.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Drug Resistance; Heme; Hemin; Mutation; Ouabain; Pyrenes | 1984 |
Mutagenicity of mono-, di- and tri-nitropyrenes in Chinese hamster ovary cells.
Topics: Animals; Cricetinae; Cricetulus; Female; Mutagenicity Tests; Mutagens; Ovary; Pyrenes | 1983 |
Tumor initiating activities of 1-nitropyrene and its nitrated products in SENCAR mice.
Topics: Administration, Topical; Animals; Female; Injections, Intraperitoneal; Male; Mice; Mutagens; Papilloma; Pyrenes; Skin Neoplasms | 1984 |
The genetic activity of dinitropyrenes in yeast: unusual dose response curves for induced mitotic gene conversion.
Topics: Cell Survival; Dimethyl Sulfoxide; Gene Conversion; Genotype; Mitosis; Mutagens; Pyrenes; Saccharomyces cerevisiae | 1981 |
The clastogenic activity of dinitropyrenes in a rat-liver epithelial cell line.
Topics: 2,4-Dinitrophenol; Animals; Cell Line; Chromosome Aberrations; Dinitrophenols; Epithelium; Kinetics; Liver; Mutagenicity Tests; Mutagens; Mutation; Pyrenes; Rats | 1982 |
The genetic activity and metabolism of dinitropyrenes in eucaryotic cells.
Topics: Animals; Biotransformation; Cell Line; Chromosome Aberrations; Humans; Liver; Microsomes, Liver; Mutagens; Pyrenes; Rats; Species Specificity; Yeasts | 1982 |
Distributions of nitropyrenes and mutagenicity in airborne particulates collected with an Andersen sampler.
Topics: Air Pollution; Chromatography, High Pressure Liquid; Mutagenicity Tests; Mutagens; Pyrenes; Salmonella typhimurium | 1995 |
Mutagenic effects of nitropyrenes in a soybean test system.
Topics: Chi-Square Distribution; Chromatography, High Pressure Liquid; Chromosome Deletion; Drug Synergism; Glycine max; Isomerism; Liver Extracts; Microsomes, Liver; Mutagenicity Tests; Mutagens; Point Mutation; Pyrenes; Structure-Activity Relationship | 1994 |
Mutagenicity of airborne particulates from combustion of electric cables in a waste metal retrieval area.
Topics: Air Pollution; Chromatography, High Pressure Liquid; Metals; Mutagenicity Tests; Mutation; Pyrenes; Salmonella typhi; Waste Products | 1994 |
The effect of fuel composition on the mutagenicity of diesel engine exhaust.
Topics: Mutagenicity Tests; Mutagens; Petroleum; Polycyclic Compounds; Pyrenes; Salmonella typhi; Vehicle Emissions | 1995 |
Dinitropyrene metabolism, DNA adduct formation, and DNA amplification in an SV40-transformed Chinese hamster embryo cell line.
Topics: Actins; Animals; Biotransformation; Cell Line, Transformed; Cell Survival; Cricetinae; Cricetulus; DNA; Embryo, Mammalian; Gene Amplification; Genes, fos; Mutagens; Pyrenes; Simian virus 40 | 1993 |
Antimutagenic activity of carotenoids in green peppers against some nitroarenes.
Topics: Antimutagenic Agents; beta Carotene; Capsicum; Carotenoids; Dose-Response Relationship, Drug; Mutagenicity Tests; Mutagens; Mutation; Plants, Medicinal; Pyrenes; Salmonella typhimurium | 1998 |
Identification of 1,6- and 1,8-dinitropyrene isomers as major mutagens in organic extracts of soil from Osaka, Japan.
Topics: Animals; Chromatography, High Pressure Liquid; In Vitro Techniques; Isomerism; Japan; Mutagenicity Tests; Mutagens; Pyrenes; Rats; Salmonella typhimurium; Soil Pollutants; Spectrophotometry, Ultraviolet | 1998 |
High-performance liquid chromatography-fluorescence determination of dinitropyrenes in soil after column chromatographic clean-up and on-line reduction.
Topics: Chromatography, High Pressure Liquid; Mutagens; Pyrenes; Sensitivity and Specificity; Soil; Soil Pollutants; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1999 |
Mutagenic activity of surface soil and quantification of 1,3-, 1,6-, and 1,8-dinitropyrene isomers in soil in Japan.
Topics: Air Pollutants; Animals; Male; Mutagens; Pyrenes; Rats; Rats, Sprague-Dawley; Soil; Soil Pollutants | 2000 |
Synthesis and characterization of oligodeoxynucleotides containing the major DNA adducts formed by 1,6- and 1,8-dinitropyrene.
Topics: DNA Adducts; Mutagens; Oligodeoxyribonucleotides; Pyrenes | 2000 |
Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1.
Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Escherichia coli; Humans; Mutagenicity Tests; Mutagens; NADPH-Ferrihemoprotein Reductase; Pyrenes; Recombinant Fusion Proteins; Salmonella typhimurium; Structure-Activity Relationship; Vehicle Emissions | 2000 |
[Suppression of frameshift mutation as a result of partial inactivation of translation termination factors in Saccharomyces cerevisiae yeast].
Topics: Base Sequence; DNA Primers; Frameshift Mutation; Fungal Proteins; Protein Biosynthesis; Pyrenes; Restriction Mapping; Saccharomyces cerevisiae; Ultraviolet Rays | 2001 |
Dinitropyrenes induce gene mutations in multiple organs of the lambda/lacZ transgenic mouse (Muta Mouse).
Topics: Animals; Base Sequence; Lac Operon; Male; Mice; Mice, Transgenic; Micronucleus Tests; Molecular Sequence Data; Mutagens; Mutation; Pyrenes; Reticulocytes; Transcription Factors; Viral Proteins | 2002 |
Comparative mutagenesis of the C8-guanine adducts of 1-nitropyrene and 1,6- and 1,8-dinitropyrene in a CpG repeat sequence. A slipped frameshift intermediate model for dinucleotide deletion.
Topics: CpG Islands; DNA Adducts; DNA Repair; DNA, Single-Stranded; Escherichia coli; Genetic Vectors; Hydrogen Bonding; Models, Molecular; Molecular Structure; Mutagenesis; Mutagens; Nucleic Acid Conformation; Phenotype; Pyrenes | 2002 |
Mutagenic activity and quantification of nitroarenes in surface soil in the Kinki region of Japan.
Topics: Animals; Benz(a)Anthracenes; Chromatography, High Pressure Liquid; Environmental Monitoring; Japan; Male; Mutagens; Pyrenes; Rats; Rats, Sprague-Dawley; Ribosomal Protein S9; Ribosomal Proteins; Salmonella typhimurium; Soil; Soil Pollutants | 2003 |
Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: possible implications for their mutagenic and carcinogenic effects.
Topics: Animals; Apoptosis; Carcinogens, Environmental; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Hepatocytes; Lipid Peroxidation; Mice; Mutagens; Phosphorylation; Pyrenes; Quantitative Structure-Activity Relationship; Signal Transduction; Tumor Suppressor Protein p53; Vehicle Emissions | 2007 |
Mutagenicity of surface soil from residential areas in Kyoto city, Japan, and identification of major mutagens.
Topics: Animals; Benzo(a)pyrene; Chromatography, High Pressure Liquid; Fluorenes; Geography; Japan; Male; Mutagenicity Tests; Mutagens; Pyrenes; Rats; Salmonella typhimurium; Soil Pollutants | 2008 |