Compounds > 1,4-dihydropyridine
Page last updated: 2024-08-26

1,4-dihydropyridine and nitrendipine

1,4-dihydropyridine has been researched along with nitrendipine in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-199041 (59.42)18.7374
1990's21 (30.43)18.2507
2000's5 (7.25)29.6817
2010's2 (2.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reider, N; Zernig, G1
Baumgarten, LB; Toscas, K; Villereal, ML1
Bladen, C; Dunn, SM1
Fox, AP; Hirning, LD; Miller, RJ1
Regan, LJ1
Fujimoto, M; Mihara, S1
Bean, BP; Regan, LJ; Sah, DW1
Hosey, MM; McMahon, KK; Ptasienski, J1
Carpenter, CL; Cooper, EC; Greenberg, DA1
Lee, HR; Roeske, WR; Watson, M; Yamamura, HI1
Brown, AM; Dumont, L; Grupp, G; Grupp, IL; Hamilton, S; Schwartz, A; Vaghy, PL; Williams, JS; Yatani, A1
Litzinger, MJ; Nelson, PG; Pun, RY1
Kongsamut, S; Miller, RJ1
Bean, BP; Hermsmeyer, K; Puga, A; Sturek, M1
Chernow, B; Ives, N; King, JW; Roth, BL1
Baldwin, JJ; Claremon, DA; Faison, EP; Kaczorowski, GJ; Lumma, PK; McClure, DE; Rosenthal, SA; Smith, GM; Trumble, MJ; Winquist, RJ1
Brown, AM; Brush, K; Hamilton, SL; Schwartz, A; Yatani, A1
Brennan, CH; Charles, S; Hudspith, MJ; Littleton, JM1
Challoner-Hue, L; Steele, TH1
Bacher, J; Bolger, GT; Isaac, L; Weissman, BA1
Oswald, RE; Simasko, SM; Weiland, GA1
Askanas, V; Desnuelle, C; Engel, WK1
Massieu, L; Tapia, R1
Dunn, SM1
Bihoreau, C; Clauser, H; Drouva, SV; Kordon, C; Laplante, E; Rasolonjanahary, R; Rerat, E1
Goldin, SM; Turner, TJ1
Freedman, SB; Kongsamut, S; Miller, RJ1
Amoroso, S; Annunziato, L; Canzoniero, LM; Di Renzo, GF; Fatatis, A; Taglialatela, M1
Hanbauer, I; Sanna, E1
Kostiuk, PG; Rozhmanova, OM; Soldatov, NM; Stel'makh, LN; Voronina, SG1
Bolger, GT; Rafferty, MF; Skolnick, P1
Burnett, JC; Ritter, SG; Strong, CG; Zachariah, PK1
Schilling, WP1
Barrett, JE; Bolger, GT; Lueddens, H; Paul, SM; Skolnick, P; Weissman, BA; Witkin, J1
Campbell, KP; Kahl, SD; Sharp, A; Strom, M1
Fairhurst, AS; Minaskanian, G; Pham, DH; Schultz, CM; Thayer, SA1
Miller, RJ; Murphy, SN; Shangold, GA1
Bowling, N; Conery, BG; Hayes, JS; Kauffman, RF1
Brandt, NR; Caswell, AH; Kawamoto, RM1
Cillero, FJ; Fau de Casa-Juana, M; Ortega, MP; Priego, JG; Sunkel, CE1
Glossmann, H; Zernig, G1
Giacomini, JC; Giacomini, KM; Nelson, WL; Zobrist, RH1
Kass, RS; Sanguinetti, MC1
Jones, H; Khandwala, A; Van Inwegen, RG; Weinryb, I1
Bolger, G; Fraser, CM; Jung, CY; Schaber, JS; Triggle, DJ; Venter, JC1
Freedman, SB; Miller, RJ1
Altura, BM; Altura, BT1
Luu, MD; Martin, JV; Mendelson, WB; Paul, SM; Skolnic, P; Wagner, R1
Gomis, A; Gutierrez, LM; Reig, JA; Sala, F; Viniegra, S1
Christensen, JD; Fjalland, B; Jørgensen, A; Treiman, M1
Azzani, T; Bianchi, G; Casirati, P; Cusi, D; Muirhead, R; Reina, MC; Soldati, L; Vezzoli, G1
Chaylakhyan, LM; Grishchenko, VM; Zherelova, OM1
Ganunis, TF; Helfaer, MA; Hoehner, PJ; Kirsch, JR; Murphy, MT; Traystman, RJ1
Blumenfeld, H; Eliot, LS; Kandel, ER; Siegelbaum, SA1
Chiu, LM; Sitges, M1
Dhein, S; Klaus, W; Salameh, A; Simsek, S; Zhao, Y1
Biancardi, E; Carbone, E; Clementi, F; Davalli, AM; Pollo, A; Pontiroli, AE; Pozza, G; Sher, E; Socci, C1
Garrigos, M; Orlowski, S; Pascaud, C1
Combs, JD; England, BP; Gordeev, MF; Gordon, EM; Jonnalagadda, S; Patel, DV1
Adachi-Akahane, S; Kanda, S; Nagao, T1
Guppy, LJ; Littleton, JM1
Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S1
Celis, H; Fagard, RH; Gasowski, J; Staessen, JA; Thijs, L; Wang, JG1
Ochi, R; Sonoda, S1
Hino, N; Masumiya, H; Ochi, R; Tsujikawa, H1
Bell-Horner, CL; Chen, ZL; Covey, DF; Das, P; Dillon, GH; Gonzales, EB; Huang, RQ; Raut, A1
Birkenhäger, WH; Bulpitt, CJ; Celis, H; de Leeuw, PW; Fagard, R; Fletcher, AE; Forette, F; Leonetti, G; McCormack, P; Nachev, C; O'Brien, E; Rodicio, JL; Rosenfeld, J; Sarti, C; Staessen, JA; Thijisq, L; Tuomilehto, J; Webster, J; Yodfat, Y; Zanchetti, A1
Aktay, G; Emre, MH; Polat, A1
Chudoba, D; Drużbicki, K; Jarek, M; Jenczyk, J; Kiwilsza, A; Mielcarek, J; Pajzderska, A; Wąsicki, J1

Reviews

2 review(s) available for 1,4-dihydropyridine and nitrendipine

ArticleYear
Are dihydropyridine binding sites voltage sensitive calcium channels?
    Life sciences, 1984, Mar-26, Volume: 34, Issue:13

    Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Ion Channels; Muscle, Smooth; Muscles; Myocardium; Neurons; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines

1984
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
    Microcirculation, endothelium, and lymphatics, 1984, Volume: 1, Issue:2

    Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cerebrovascular Circulation; Cerebrovascular Disorders; Coronary Disease; Diabetes Mellitus; Dihydropyridines; Female; Humans; Hypertension; Ketamine; Magnesium; Magnesium Deficiency; Microcirculation; Muscle, Smooth, Vascular; Muscles; Nifedipine; Nisoldipine; Nitrendipine; Nutritional Requirements; Pentobarbital; Pre-Eclampsia; Pregnancy; Pyridines; Rats; Vasoconstrictor Agents; Vasodilator Agents; Venules

1984

Trials

2 trial(s) available for 1,4-dihydropyridine and nitrendipine

ArticleYear
Dihydropyridine calcium-channel blockers for antihypertensive treatment in older patients--evidence from the Systolic Hypertension in Europe Trial.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2001, Volume: 91, Issue:12

    Topics: Aged; Alcohol Drinking; Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Double-Blind Method; Europe; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Prognosis; Smoking; Treatment Outcome

2001
Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial.
    Journal of hypertension, 2004, Volume: 22, Issue:4

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus; Dihydropyridines; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Europe; Female; Follow-Up Studies; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Incidence; Linear Models; Male; Myocardial Infarction; Nitrendipine; Stroke; Survival Rate; Time Factors; Treatment Outcome

2004

Other Studies

65 other study(ies) available for 1,4-dihydropyridine and nitrendipine

ArticleYear
Ion dependence of the partially purified mitochondrial dihydropyridine Ca2+ antagonist receptor.
    Molecular pharmacology, 1992, Volume: 41, Issue:1

    Topics: Animals; Anions; Binding Sites; Calcium Channels; Cations; Dihydropyridines; Guinea Pigs; Kinetics; Mitochondria, Liver; Nitrendipine; Receptors, Nicotinic; Tritium

1992
Dihydropyridine-sensitive L-type Ca2+ channels in human foreskin fibroblast cells. Characterization of activation with the growth factor Lys-bradykinin.
    The Journal of biological chemistry, 1992, May-25, Volume: 267, Issue:15

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channels; Cells, Cultured; Dihydropyridines; Fibroblasts; Fura-2; Humans; Ion Channel Gating; Kallidin; Nitrendipine

1992
Kinetics of binding of dihydropyridine calcium channel ligands to skeletal muscle membranes: evidence for low-affinity sites and for the involvement of G proteins.
    Biochemistry, 1991, Jun-11, Volume: 30, Issue:23

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Isradipine; Kinetics; Ligands; Membrane Proteins; Microsomes; Muscles; Nitrendipine; Oxadiazoles; Rabbits; Receptors, Nicotinic; Stereoisomerism; Thionucleotides

1991
Inhibition of calcium currents in cultured myenteric neurons by neuropeptide Y: evidence for direct receptor/channel coupling.
    Brain research, 1990, Nov-05, Volume: 532, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cells, Cultured; Dihydropyridines; Fura-2; Membrane Potentials; Myenteric Plexus; Neurons; Neuropeptide Y; Nitrendipine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Neuropeptide Y; Receptors, Neurotransmitter; Virulence Factors, Bordetella

1990
Voltage-dependent calcium currents in Purkinje cells from rat cerebellar vermis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Barium; Calcium Channels; Cell Separation; Dihydropyridines; Electric Conductivity; Electrophysiology; Nickel; Nimodipine; Nitrendipine; Purkinje Cells; Rats

1991
Effect of S-312, a new calcium channel blocker, on the 1,4-dihydropyridine binding sites in porcine basilar blood vessels and rat aortic smooth muscle cells.
    Japanese journal of pharmacology, 1991, Volume: 56, Issue:3

    Topics: Animals; Aorta; Basilar Artery; Binding Sites; Calcium; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Isradipine; Muscle, Smooth, Vascular; Nicardipine; Nitrendipine; Oxadiazoles; Rats; Swine

1991
Ca2+ channels in rat central and peripheral neurons: high-threshold current resistant to dihydropyridine blockers and omega-conotoxin.
    Neuron, 1991, Volume: 6, Issue:2

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Central Nervous System; Differential Threshold; Dihydropyridines; Drug Resistance; Electrophysiology; Kinetics; Neurons; Nitrendipine; omega-Conotoxin GVIA; Osmolar Concentration; Peptides, Cyclic; Peripheral Nerves; Rats

1991
High and low affinity states of the dihydropyridine and phenylalkylamine receptors on the cardiac calcium channel and their interconversion by divalent cations.
    Biochemical and biophysical research communications, 1985, Jun-28, Volume: 129, Issue:3

    Topics: Animals; Calcium; Cations, Divalent; Chickens; Dihydropyridines; Heart; Ion Channels; Isradipine; Magnesium; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil

1985
Stimulation of calcium uptake in PC12 cells by the dihydropyridine agonist BAY K 8644.
    Journal of neurochemistry, 1985, Volume: 45, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Nifedipine; Nitrendipine; Pheochromocytoma; Pyridines; Rats

1985
Decreased [3H]nitrendipine binding in the brainstem of deoxycorticosterone-NaCl hypertensive rats.
    Life sciences, 1985, Sep-09, Volume: 37, Issue:10

    Topics: Animals; Brain Stem; Calcium; Desoxycorticosterone; Dihydropyridines; Hypertension; Ion Channels; Kidney; Kinetics; Male; Myocardium; Nephrectomy; Nifedipine; Nitrendipine; Organ Size; Pyridines; Rats; Sodium Chloride

1985
Profile of the oppositely acting enantiomers of the dihydropyridine 202-791 in cardiac preparations: receptor binding, electrophysiological, and pharmacological studies.
    Biochemical and biophysical research communications, 1985, Aug-30, Volume: 131, Issue:1

    Topics: Animals; Binding, Competitive; Calcium; Dihydropyridines; Dogs; Electric Conductivity; Guinea Pigs; Heart; Ion Channels; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Papillary Muscles; Pyridines; Sarcolemma; Stereoisomerism; Ventricular Function

1985
Effects of nitrendipine on the voltage-sensitive calcium channel in mammalian sensory neurons.
    Journal of neuroscience research, 1985, Volume: 14, Issue:4

    Topics: Action Potentials; Animals; Cells, Cultured; Dihydropyridines; Electric Stimulation; Ethanol; Ganglia, Spinal; Ion Channels; Mice; Nerve Growth Factors; Neurons, Afferent; Nifedipine; Nitrendipine; Pharmaceutical Vehicles; Pyridines; Reaction Time; Temperature

1985
Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bucladesine; Calcium; Cell Differentiation; Dihydropyridines; Nerve Growth Factors; Nifedipine; Nitrendipine; Norepinephrine; Pheochromocytoma; Potassium; Pyridines; Rats; Secretory Rate

1986
Calcium channels in muscle cells isolated from rat mesenteric arteries: modulation by dihydropyridine drugs.
    Circulation research, 1986, Volume: 59, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Pyridines; Rats

1986
BAY k 8644, a calcium channel agonist, reverses hypotension in endotoxin-shocked rats.
    European journal of pharmacology, 1986, Nov-04, Volume: 130, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Male; Microsomes; Myocardium; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Shock, Septic

1986
Diethyl 3,6-dihydro-2,4-dimethyl-2,6-methano-1,3-benzothiazocine-5,11- dicarboxylates as calcium entry antagonists: new conformationally restrained analogues of Hantzsch 1,4-dihydropyridines related to nitrendipine as probes for receptor-site conformation
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:4

    Topics: Animals; Aorta; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Dose-Response Relationship, Drug; Heterocyclic Compounds; Ion Channels; Male; Nitrendipine; Protein Binding; Pyridines; Rats; Rats, Inbred Strains; Sarcolemma; Structure-Activity Relationship; Swine; Terpenes

1987
A comparison between the binding and electrophysiological effects of dihydropyridines on cardiac membranes.
    Molecular pharmacology, 1987, Volume: 31, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Heart; Ion Channels; Isradipine; Kinetics; Membrane Potentials; Membranes; Myocardium; Nicotinic Acids; Nimodipine; Nitrendipine; Oxadiazoles; Pyridines; Stereoisomerism; Structure-Activity Relationship

1987
Dihydropyridine-sensitive Ca2+ channels and inositol phospholipid metabolism in ethanol physical dependence.
    Annals of the New York Academy of Sciences, 1987, Volume: 492

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alcoholism; Animals; Cerebral Cortex; Dihydropyridines; Hydroxydopamines; In Vitro Techniques; Inositol Phosphates; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nitrendipine; Oxidopamine; Pyridines; Rats; Rats, Inbred Strains; Sugar Phosphates; Vas Deferens

1987
Dihydropyridine calcium antagonists and agonists in the isolated perfused Dahl rat kidney.
    Journal of cardiovascular pharmacology, 1987, Volume: 9 Suppl 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Glomerular Filtration Rate; Hypertension, Renal; In Vitro Techniques; Ion Channels; Kidney; Male; Nitrendipine; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Renal Circulation; Sodium Chloride; Verapamil

1987
Calcium antagonist binding in cat brain tolerant to electroconvulsive shock.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:2

    Topics: Animals; Binding Sites; Brain; Cats; Cerebellum; Cerebral Cortex; Dihydropyridines; Electroshock; Female; Hippocampus; Ion Channels; Male; Nitrendipine; Pyridines; Tissue Distribution

1987
Pharmacological characterization of two calcium currents in GH3 cells.
    The American journal of physiology, 1988, Volume: 254, Issue:3 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Dihydropyridines; Electrophysiology; Ion Channels; Nitrendipine; Osmolar Concentration; Pituitary Gland; Rats

1988
Dihydropyridine-sensitive Ca2+ channel in aneurally cultured human muscles. Relationship between high-affinity binding site and inhibition of calcium uptake.
    FEBS letters, 1988, Mar-28, Volume: 230, Issue:1-2

    Topics: Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cells, Cultured; Dihydropyridines; Electrophysiology; Humans; Ion Channels; Isradipine; Muscles; Nitrendipine; Oxadiazoles; Potassium

1988
Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes.
    Journal of neurochemistry, 1988, Volume: 51, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; gamma-Aminobutyric Acid; Ion Channels; Isradipine; Lanthanum; Male; Mice; Neurotransmitter Agents; Nifedipine; Nitrendipine; Oxadiazoles; Potassium; Receptors, Nicotinic; Ruthenium Red; Synaptosomes

1988
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function.
    Biochemistry, 1988, Jul-12, Volume: 27, Issue:14

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil

1988
Dihydropyridine-sensitive calcium channel activity related to prolactin, growth hormone, and luteinizing hormone release from anterior pituitary cells in culture: interactions with somatostatin, dopamine, and estrogens.
    Endocrinology, 1988, Volume: 123, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Calcium Radioisotopes; Cells, Cultured; Dihydropyridines; Dopamine; Estradiol; Female; Growth Hormone; Luteinizing Hormone; Male; Nitrendipine; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Potassium; Prolactin; Rats; Rats, Inbred Strains; Sex Characteristics; Somatostatin

1988
Calcium channels in rat brain synaptosomes: identification and pharmacological characterization. High affinity blockade by organic Ca2+ channel blockers.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:3

    Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Ion Channels; Male; Nifedipine; Nitrendipine; Norepinephrine; Potassium; Pyridines; Rats; Rats, Inbred Strains; Synaptosomes

1985
Dihydropyridine sensitive calcium channels in a smooth muscle cell line.
    Biochemical and biophysical research communications, 1985, Feb-28, Volume: 127, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Cobalt; Dihydropyridines; Ion Channels; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium; Pyridines; Rats

1985
Cobalt-sensitive and dihydropyridine-insensitive stimulation of dopamine release from tuberoinfundibular neurons by high extracellular concentrations of barium ions.
    Brain research, 1989, May-29, Volume: 488, Issue:1-2

    Topics: Animals; Barium; Cations, Divalent; Cobalt; Dihydropyridines; Dopamine; Female; Hypothalamus; Nitrendipine; Rats; Rats, Inbred Strains

1989
Voltage-dependent Ca2+ channels in primary cultures of cerebellar granule cells: modulatory action by an endogenous ligand.
    Pharmacological research communications, 1988, Volume: 20, Issue:12

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebellum; Dihydropyridines; Nitrendipine; Rats; Receptors, Nicotinic; Veratridine

1988
[Reconstruction of a purified and functionally active dihydropyridine-sensitive calcium channel into liposomes].
    Doklady Akademii nauk SSSR, 1988, Volume: 301, Issue:6

    Topics: Animals; Biological Transport; Calcium Channels; Dihydropyridines; In Vitro Techniques; Liposomes; Nitrendipine; Rabbits; Receptors, Nicotinic

1988
Phencyclidine increases the affinity of dihydropyridine calcium channel antagonist binding in rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 330, Issue:3

    Topics: Animals; Binding Sites; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Kinetics; Magnesium; Male; Nifedipine; Nitrendipine; Phencyclidine; Pyridines; Rats; Rats, Inbred Strains

1985
Atrial natriuretic peptide in human essential hypertension.
    Mayo Clinic proceedings, 1987, Volume: 62, Issue:9

    Topics: Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Middle Aged; Nitrendipine; Pyridines

1987
Effect of divalent cation chelation on dihydropyridine binding in isolated cardiac sarcolemma vesicles.
    Biochimica et biophysica acta, 1988, Aug-18, Volume: 943, Issue:2

    Topics: Animals; Calcimycin; Calcium; Cations, Divalent; Dihydropyridines; Dogs; Edetic Acid; Hydrogen-Ion Concentration; Isradipine; Magnesium; Myocardium; Nitrendipine; Ouabain; Oxadiazoles; Phosphates; Sarcolemma

1988
Dihydropyridine calcium channel antagonists binding in non-mammalian vertebrates: characterization and relationship to 'peripheral-type' binding sites for benzodiazepines.
    Brain research, 1986, Mar-19, Volume: 368, Issue:2

    Topics: Animals; Brain; Calcium Channels; Columbidae; Dihydropyridines; Female; Kinetics; Lizards; Male; Membranes; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rana catesbeiana; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Nicotinic; Species Specificity; Trout

1986
High-affinity antibodies to the 1,4-dihydropyridine Ca2+-channel blockers.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:9

    Topics: Animals; Antibodies; Antibody Specificity; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Nifedipine; Nitrendipine; Pyridines; Rabbits; Receptors, Nicotinic; Structure-Activity Relationship; Tritium

1986
An antibody to dihydropyridine calcium entry blockers. A comparison with the calcium channel receptor in skeletal muscle.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Antibodies; Antibody Affinity; Antibody Specificity; Antigens; Calcium Channel Blockers; Calcium Channels; Chemical Phenomena; Chemistry; Dihydropyridines; Haptens; Muscles; Nitrendipine; Pyridines; Receptors, Nicotinic

1986
Gonadotropin-releasing hormone-induced Ca2+ transients in single identified gonadotropes require both intracellular Ca2+ mobilization and Ca2+ influx.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:17

    Topics: Animals; Calcium; Cells, Cultured; Dihydropyridines; Female; Gonadotropin-Releasing Hormone; Nitrendipine; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains

1988
Phosphorylation of ventricular sarcolemmal membranes does not alter binding properties of nitrendipine.
    Biochimica et biophysica acta, 1985, Jan-25, Volume: 812, Issue:2

    Topics: Alamethicin; Animals; Cats; Dihydropyridines; Dose-Response Relationship, Drug; Female; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Phosphorylation; Protein Kinases; Pyridines; Sarcolemma; Time Factors

1985
Effects of mercaptans upon dihydropyridine binding sites on transverse tubules isolated from triads of rabbit skeletal muscle.
    Biochemical and biophysical research communications, 1985, Feb-28, Volume: 127, Issue:1

    Topics: Animals; Digoxin; Dihydropyridines; Dithiothreitol; Glutathione; Glutathione Disulfide; Muscles; Nifedipine; Nitrendipine; Ouabain; Pyridines; Rabbits; Sulfhydryl Compounds

1985
Synthesis, platelet aggregation inhibitory activity, and in vivo antithrombotic activity of new 1,4-dihydropyridines.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:10

    Topics: Animals; Cats; Collagen; Dihydropyridines; Humans; Kinetics; Male; Mice; Nitrendipine; Platelet Aggregation; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thrombosis

1988
A novel 1,4-dihydropyridine-binding site on mitochondrial membranes from guinea-pig heart, liver and kidney.
    The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1

    Topics: Animals; Binding Sites; Centrifugation, Density Gradient; Dihydropyridines; Diltiazem; Guinea Pigs; Intracellular Membranes; Kidney; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Nitrendipine; Osmolar Concentration; Subcellular Fractions; Verapamil

1988
The interaction of phenylalkylamine calcium channel blockers with the 1,4-dihydropyridine binding site.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:9

    Topics: Animals; Binding Sites; Calcium Channel Blockers; Dihydropyridines; Heart; Kinetics; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Drug; Structure-Activity Relationship; Verapamil

1986
Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.
    Circulation research, 1984, Volume: 55, Issue:3

    Topics: Animals; Binding Sites; Cattle; Dihydropyridines; Electrophysiology; Heart Conduction System; Ion Channels; Membrane Potentials; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Pyridines; Verapamil

1984
Comparative structure-activity relationships for dihydropyridines as inhibitors of [3H]-nitrendipine binding vs cyclic nucleotide phosphodiesterases.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 45, Issue:2

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Binding, Competitive; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Kinetics; Male; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rats; Structure-Activity Relationship

1984
Molecular properties of the slow inward calcium channel. Molecular weight determinations by radiation inactivation and covalent affinity labeling.
    The Journal of biological chemistry, 1983, Aug-10, Volume: 258, Issue:15

    Topics: Affinity Labels; Animals; Calcium; Dihydropyridines; Guinea Pigs; Ion Channels; Methods; Molecular Weight; Muscles; Nifedipine; Nitrendipine; Pyridines

1983
Diazepam-stimulated increases in the synaptosomal uptake of 45Ca2+: reversal by dihydropyridine calcium channel antagonists.
    European journal of pharmacology, 1984, Sep-03, Volume: 104, Issue:1-2

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Calcium Radioisotopes; Cerebral Cortex; Diazepam; Dihydropyridines; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Synaptosomes

1984
Ruthenium red inhibits selectively chromaffin cell calcium channels.
    Biochemical pharmacology, 1994, Jan-20, Volume: 47, Issue:2

    Topics: Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Dihydropyridines; Enterochromaffin Cells; Iodine Radioisotopes; Nitrendipine; Norepinephrine; omega-Conotoxin GVIA; Peptides; Ruthenium Red; Tritium

1994
Dihydropyridine ligands influence the evoked release of oxytocin and vasopressin dependent on stimulation conditions.
    European journal of pharmacology, 1994, Jul-01, Volume: 259, Issue:2

    Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Electric Stimulation; Electrophysiology; Female; Ligands; Nicotinic Acids; Nitrendipine; Oxadiazoles; Oxytocin; Pituitary Gland, Posterior; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Vasopressins

1994
Erythrocyte membrane calcium transport in patients with primary hyperparathyroidism.
    Biochemical and biophysical research communications, 1994, Aug-15, Volume: 202, Issue:3

    Topics: Biological Transport; Ca(2+) Mg(2+)-ATPase; Calcium; Dihydropyridines; Erythrocyte Membrane; Female; Humans; Hyperparathyroidism; Male; Middle Aged; Nitrendipine; Strontium

1994
Blockers of Ca2+ channels in the plasmalemma of perfused Characeae cells.
    Comparative biochemistry and physiology. Pharmacology, toxicology and endocrinology, 1994, Volume: 107, Issue:3

    Topics: Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chlorophyta; Dihydropyridines; Membrane Potentials; Nifedipine; Nitrendipine; Perfusion; Pyridines

1994
Dihydropyridine ligand binding decreases earlier in adolescent than in infant swine after global cerebral ischemia.
    Stroke, 1994, Volume: 25, Issue:10

    Topics: Aging; Animals; Blood Pressure; Brain Ischemia; Calcium Channels; Caudate Nucleus; Cerebral Cortex; Dihydropyridines; Hippocampus; Isradipine; Ligands; Membrane Proteins; Nitrendipine; Protein Binding; Swine; Synaptosomes; Time Factors

1994
Imaging terminals of Aplysia sensory neurons demonstrates role of enhanced Ca2+ influx in presynaptic facilitation.
    Nature, 1993, Feb-18, Volume: 361, Issue:6413

    Topics: Action Potentials; Animals; Aplysia; Calcium; Calcium Channels; Dihydropyridines; Motor Neurons; Neuronal Plasticity; Neurons, Afferent; Nitrendipine; Potassium Channels; Serotonin; Synapses

1993
Characterization of the type of calcium channel primarily regulating GABA exocytosis from brain nerve endings.
    Neurochemical research, 1995, Volume: 20, Issue:9

    Topics: Animals; Brain; Cadmium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Exocytosis; gamma-Aminobutyric Acid; Male; Mice; Mollusk Venoms; Nerve Endings; Nickel; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxins; Peptides; Spider Venoms

1995
Actions of 1,4-dihydropyridines in isolated mesenteric vascular beds.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:5

    Topics: Animals; Arginine; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Arteries; Nifedipine; Nitrendipine; Nitric Oxide; Nitroarginine; Vasodilation

1995
Dihydropyridine-sensitive and -insensitive voltage-operated calcium channels participate in the control of glucose-induced insulin release from human pancreatic beta cells.
    The Journal of endocrinology, 1996, Volume: 150, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Mollusk Venoms; Nitrendipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides

1996
Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents.
    The Biochemical journal, 1998, Jul-15, Volume: 333 ( Pt 2)

    Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Calcium Channel Blockers; CHO Cells; Cricetinae; Cytotoxins; Dihydropyridines; Drug Resistance, Multiple; Fibroblasts; Nicardipine; Nimodipine; Nitrendipine; Protein Binding; Verapamil; Vinblastine

1998
Combinatorial synthesis and screening of a chemical library of 1,4-dihydropyridine calcium channel blockers.
    Bioorganic & medicinal chemistry, 1998, Volume: 6, Issue:7

    Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Dihydropyridines; Drug Evaluation, Preclinical; In Vitro Techniques; Nitrendipine; Radioligand Assay; Rats

1998
Functional interaction between benzothiazepine- and dihydropyridine binding sites of cardiac L-type Ca2+ channels.
    European journal of pharmacology, 1998, Oct-09, Volume: 358, Issue:3

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cell Line; Dihydropyridines; Diltiazem; Membrane Potentials; Myocardium; Nitrendipine; Patch-Clamp Techniques; Temperature; Thiazepines; Time Factors

1998
Effects of prolonged exposure to ethanol in vivo on functional parameters and sensitivity to nitrendipine in the isolated rat heart.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:3

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Drug Interactions; Ethanol; Heart; Male; Myocardium; Nitrendipine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

1999
Calcium channel activation and self-biting in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Dec-21, Volume: 96, Issue:26

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior

1999
Independent modulation of L-type Ca2+ channel in guinea pig ventricular cells by nitrendipine and isoproterenol.
    Japanese heart journal, 2001, Volume: 42, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Colforsin; Dihydropyridines; Electrophysiology; Evoked Potentials; Guinea Pigs; Heart Ventricles; Isoproterenol; Nitrendipine; Patch-Clamp Techniques; Phosphorylation

2001
Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells.
    Pflugers Archiv : European journal of physiology, 2003, Volume: 446, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Colforsin; Cyclic AMP; Dihydropyridines; Electrophysiology; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Ion Channels; Isoproterenol; Manganese; Membrane Potentials; Myocardium; Myocytes, Cardiac; Nitrendipine; Patch-Clamp Techniques; Rabbits; Signal Transduction

2003
Inhibition of type A GABA receptors by L-type calcium channel blockers.
    Neuroscience, 2004, Volume: 124, Issue:1

    Topics: 4-Butyrolactone; Animals; Benzodiazepines; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Humans; Hypothalamus; Kidney; Mutagenesis, Site-Directed; Nitrendipine; Picrotoxin; Protein Structure, Tertiary; Rats; Receptors, GABA-A; Recombinant Proteins; Solvents; Species Specificity; Zinc

2004
Influence of dihydropyridine calcium antagonist nitrendipine on benzo(a)pyrene-induced oxidative stress.
    Archives of pharmacal research, 2011, Volume: 34, Issue:7

    Topics: Animals; Antioxidants; Aspartate Aminotransferases; Benzo(a)pyrene; Brain; Calcium Channel Blockers; Dihydropyridines; Glutathione; Hazardous Substances; Liver; Liver Function Tests; Lung; Male; Nitrendipine; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2011
In search of the mutual relationship between the structure, solid-state spectroscopy and molecular dynamics in selected calcium channel blockers.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Mar-31, Volume: 85

    Topics: Calcium Channel Blockers; Crystallization; Dihydropyridines; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Nifedipine; Nimodipine; Nitrendipine; Quantum Theory; Spectrophotometry, Infrared; X-Ray Diffraction

2016