Page last updated: 2024-09-03

1,4-dihydro-2,6-dimethyl-4-phenyl-3,5-pyridinecarboxylic acid dimethyl ester and nimodipine

1,4-dihydro-2,6-dimethyl-4-phenyl-3,5-pyridinecarboxylic acid dimethyl ester has been researched along with nimodipine in 1 studies

Compound Research Comparison

Studies
(1,4-dihydro-2,6-dimethyl-4-phenyl-3,5-pyridinecarboxylic acid dimethyl ester)
Trials
(1,4-dihydro-2,6-dimethyl-4-phenyl-3,5-pyridinecarboxylic acid dimethyl ester)
Recent Studies (post-2010)
(1,4-dihydro-2,6-dimethyl-4-phenyl-3,5-pyridinecarboxylic acid dimethyl ester)
Studies
(nimodipine)
Trials
(nimodipine)
Recent Studies (post-2010) (nimodipine)
10032,936317597

Protein Interaction Comparison

ProteinTaxonomy1,4-dihydro-2,6-dimethyl-4-phenyl-3,5-pyridinecarboxylic acid dimethyl ester (IC50)nimodipine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.11
Cytochrome P450 2C9 Homo sapiens (human)2.19
Cannabinoid receptor 1Homo sapiens (human)1.736
Cytochrome P450 2C19Homo sapiens (human)4
Cytochrome P450 2J2Homo sapiens (human)3.38
Voltage-dependent calcium channel subunit alpha-2/delta-1Homo sapiens (human)0.0298
Voltage-dependent L-type calcium channel subunit beta-2Homo sapiens (human)0.0298
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)7.15
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0699
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)1.243
Bile acid receptorHomo sapiens (human)8.96

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Böcker, RH; Guengerich, FP1

Other Studies

1 other study(ies) available for 1,4-dihydro-2,6-dimethyl-4-phenyl-3,5-pyridinecarboxylic acid dimethyl ester and nimodipine

ArticleYear
Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Chemical Phenomena; Chemistry; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Microsomes, Liver; NADP; Nifedipine; Oxidation-Reduction

1986