1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester has been researched along with nifedipine in 6 studies
| Studies (1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester) | Trials (1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester) | Recent Studies (post-2010) (1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester) | Studies (nifedipine) | Trials (nifedipine) | Recent Studies (post-2010) (nifedipine) |
|---|---|---|---|---|---|
| 6 | 0 | 1 | 16,024 | 2,496 | 1,505 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersen, N; Gougoutas, J; Hedberg, A; Kimball, SD; Malley, M; Moreland, S; Porubcan, M; Pudzianowski, A; Rovnyak, G | 1 |
| Coburn, RA; Solo, AJ; Suto, MJ; Triggle, AM; Triggle, DJ; Wierzba, M | 1 |
| Dagnino, L; Knaus, EE; Li-Kwong-Ken, MC; Triggle, CR; Wolowyk, MW; Wynn, H | 1 |
| Fossheim, R; Mostad, A; Rømming, C; Shefter, E; Svarteng, K; Triggle, DJ | 1 |
| Cao, S; Chang, CC; Dunne, SF; Kai, L; Kang, S; Luan, CH; Pandey, P; Silverman, RB; Surmeier, DJ; Tian, X | 1 |
| Caron, G; Ermondi, G; Galietta, L; Medana, C; Pedemonte, N; Visentin, S | 1 |
6 other study(ies) available for 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester and nifedipine
| Article | Year |
|---|---|
Studies directed toward ascertaining the active conformation of 1,4-dihydropyridine calcium entry blockers.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Models, Molecular; Molecular Conformation; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Radioligand Assay; Receptors, Nicotinic; Structure-Activity Relationship | 1988 |
1,4-Dihydropyridine antagonist activities at the calcium channel: a quantitative structure-activity relationship approach.
Topics: Animals; Calcium Channels; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Mathematics; Muscle Contraction; Structure-Activity Relationship | 1988 |
Synthesis and calcium channel antagonist activity of dialkyl 4- (dihydropyridinyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylates.
Topics: Animals; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dicarboxylic Acids; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Receptors, Muscarinic; Structure-Activity Relationship | 1987 |
Crystal structures and pharmacological activity of calcium channel antagonists: 2,6-dimethyl-3,5-dicarbomethoxy-4-(unsubstituted, 2-methyl-, 4-methyl-, 3-nitro-, 4-nitro-, and 2,4-dinitrophenyl)-1,4-dihydropyridine.
Topics: Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Models, Molecular; Molecular Conformation; Nifedipine; Phosphorylcholine; Pyridines; Structure-Activity Relationship; X-Ray Diffraction | 1982 |
Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Dicarboxylic Acids; Dihydropyridines; Humans; Inhibitory Concentration 50; Molecular Structure; Nifedipine | 2010 |
Ligand-based design, in silico ADME-Tox filtering, synthesis and biological evaluation to discover new soluble 1,4-DHP-based CFTR activators.
Topics: Absorption; Animals; Calcium Channel Blockers; Chemistry Techniques, Synthetic; Computational Biology; Cystic Fibrosis Transmembrane Conductance Regulator; Dihydropyridines; Drug Design; Humans; Ligands; Models, Molecular; Mutation; Protein Conformation; Quantitative Structure-Activity Relationship; Rats; Solubility | 2012 |