1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester and diethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester has been researched along with diethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate in 2 studies

Compound Research Comparison

Studies (1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester)	Trials (1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester)	Recent Studies (post-2010) (1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester)	Studies (diethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate)	Trials (diethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate)	Recent Studies (post-2010) (diethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate)
6	0	1	10	0	3

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cao, S; Chang, CC; Dunne, SF; Kai, L; Kang, S; Luan, CH; Pandey, P; Silverman, RB; Surmeier, DJ; Tian, X	1
Caron, G; Ermondi, G; Galietta, L; Medana, C; Pedemonte, N; Visentin, S	1

Other Studies

2 other study(ies) available for 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester and diethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Article	Year
Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2. Bioorganic & medicinal chemistry, 2010, May-01, Volume: 18, Issue:9 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Dicarboxylic Acids; Dihydropyridines; Humans; Inhibitory Concentration 50; Molecular Structure; Nifedipine	2010
Ligand-based design, in silico ADME-Tox filtering, synthesis and biological evaluation to discover new soluble 1,4-DHP-based CFTR activators. European journal of medicinal chemistry, 2012, Volume: 55 Topics: Absorption; Animals; Calcium Channel Blockers; Chemistry Techniques, Synthetic; Computational Biology; Cystic Fibrosis Transmembrane Conductance Regulator; Dihydropyridines; Drug Design; Humans; Ligands; Models, Molecular; Mutation; Protein Conformation; Quantitative Structure-Activity Relationship; Rats; Solubility	2012

Article

Year

Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.

Bioorganic & medicinal chemistry, 2010, May-01, Volume: 18, Issue:9

Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Dicarboxylic Acids; Dihydropyridines; Humans; Inhibitory Concentration 50; Molecular Structure; Nifedipine

2010

Ligand-based design, in silico ADME-Tox filtering, synthesis and biological evaluation to discover new soluble 1,4-DHP-based CFTR activators.

European journal of medicinal chemistry, 2012, Volume: 55

Topics: Absorption; Animals; Calcium Channel Blockers; Chemistry Techniques, Synthetic; Computational Biology; Cystic Fibrosis Transmembrane Conductance Regulator; Dihydropyridines; Drug Design; Humans; Ligands; Models, Molecular; Mutation; Protein Conformation; Quantitative Structure-Activity Relationship; Rats; Solubility

2012