Compounds > 1,4-diethynylbenzene
Page last updated: 2024-09-03

1,4-diethynylbenzene and verapamil

1,4-diethynylbenzene has been researched along with verapamil in 1 studies

Compound Research Comparison

Studies
(1,4-diethynylbenzene)		Trials
(1,4-diethynylbenzene)		Recent Studies (post-2010)
(1,4-diethynylbenzene)		Studies
(verapamil)		Trials
(verapamil)		Recent Studies (post-2010) (verapamil)
70317,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomy1,4-diethynylbenzene (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, KF; Chan, TH; Chow, LMC; Hu, X; Law, MC; Lo, AMY; Wong, ILK; Zhu, X1

Other Studies

1 other study(ies) available for 1,4-diethynylbenzene and verapamil

ArticleYear
Discovery of Novel Flavonoid Dimers To Reverse Multidrug Resistance Protein 1 (MRP1, ABCC1) Mediated Drug Resistance in Cancers Using a High Throughput Platform with "Click Chemistry".
    Journal of medicinal chemistry, 2018, 11-21, Volume: 61, Issue:22

    Topics: Alkynes; Animals; Antineoplastic Agents; Azides; Cell Line, Tumor; Click Chemistry; Dimerization; Doxorubicin; Drug Design; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Female; Flavonoids; Humans; Intracellular Space; Mice; Molecular Docking Simulation; Multidrug Resistance-Associated Proteins; Protein Conformation

2018