Page last updated: 2024-09-03

1,4-dideoxy-1,4-iminoarabinitol and miglustat

1,4-dideoxy-1,4-iminoarabinitol has been researched along with miglustat in 2 studies

Compound Research Comparison

Studies
(1,4-dideoxy-1,4-iminoarabinitol)
Trials
(1,4-dideoxy-1,4-iminoarabinitol)
Recent Studies (post-2010)
(1,4-dideoxy-1,4-iminoarabinitol)
Studies
(miglustat)
Trials
(miglustat)
Recent Studies (post-2010) (miglustat)
5802538328185

Protein Interaction Comparison

ProteinTaxonomy1,4-dideoxy-1,4-iminoarabinitol (IC50)miglustat (IC50)
Sucrase-isomaltase Mus musculus (house mouse)1.05
Maltase-glucoamylase, intestinalHomo sapiens (human)5.55
Lysosomal acid glucosylceramidaseHomo sapiens (human)5
Lysosomal alpha-glucosidaseHomo sapiens (human)0.1
Sucrase-isomaltase, intestinalHomo sapiens (human)0.5
Sucrase-isomaltase, intestinalRattus norvegicus (Norway rat)2.156
Protein-lysine 6-oxidaseHomo sapiens (human)5
Glycogen debranching enzymeHomo sapiens (human)10
Lysosomal alpha-glucosidaseMus musculus (house mouse)9
Non-lysosomal glucosylceramidaseMus musculus (house mouse)0.14
Lysosomal alpha-glucosidaseRattus norvegicus (Norway rat)3.7
Non-lysosomal glucosylceramidaseHomo sapiens (human)0.2057
Putative alpha-glucosidaseOryza sativa Japonica Group (Japanese rice)0.42

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Adachi, I; Hayashi, E; Hirono, S; Imahori, T; Kato, A; Koseki, J; Miyauchi, S; Nakagome, I; Nash, RJ; Natori, Y; Shimaoka, H; Takahata, H; Yoshimura, Y1
Fleet, GWJ; Jia, YM; Kanekiyo, U; Kato, A; Kishida, M; Li, YX; Lu, TT; Nakagome, I; Nash, RJ; Shinzawa, K; Tanaka, N; Yoshida, T; Yoshimura, K; Yu, CY1

Other Studies

2 other study(ies) available for 1,4-dideoxy-1,4-iminoarabinitol and miglustat

ArticleYear
α-1-C-butyl-1,4-dideoxy-1,4-imino-l-arabinitol as a second-generation iminosugar-based oral α-glucosidase inhibitor for improving postprandial hyperglycemia.
    Journal of medicinal chemistry, 2012, Dec-13, Volume: 55, Issue:23

    Topics: Administration, Oral; Animals; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Imino Sugars; Inhibitory Concentration 50; Male; Mice; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2012
5-
    Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3

    Topics: 1-Deoxynojirimycin; Alkylation; alpha-Glucosidases; Enzyme Inhibitors; Fibroblasts; Glycogen Storage Disease Type II; Humans; Molecular Dynamics Simulation; Molecular Structure; Mutation; Protein Conformation; Protein Stability; Recombinant Proteins

2022