1-4-dideoxy-1-4-imino-d-arabinitol has been researched along with 1-4-dideoxy-1-4-iminoarabinitol* in 1 studies
1 other study(ies) available for 1-4-dideoxy-1-4-imino-d-arabinitol and 1-4-dideoxy-1-4-iminoarabinitol
Article | Year |
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Occurrence of the alpha-glucosidase inhibitor 1,4-Dideoxy-1,4-imino-D-arabinitol and related iminopentitols in marine sponges.
The alpha-glucosidase inhibitor 1,4-dideoxy-1,4-imino-D-arabinitol (1) was isolated from two marine sponges collected in Western Australia and shown by LC-MS to be responsible for the alpha-glycosidase inhibitory activity in different sponge extracts collected over a wide geographic area. The configuration of 1 was determined by application of Marfey's method. The two most inhibitory extracts contained only 1, while the less inhibitory extracts contained 1,4-dideoxy-1,4-imino-D-xylitol (2) or the putative diastereomeric imino pentitols 3 and 4. The least active or inactive extracts showed no detectable imino pentitols. While both 1 and 2 are known from plants, this is the first report on the isolation and detection of 1 and 2 in marine invertebrates. Topics: Animals; Arabinose; Glycoside Hydrolase Inhibitors; Imino Furanoses; Molecular Structure; Porifera; Sugar Alcohols; Western Australia; Xylitol; Yeasts | 2007 |