Page last updated: 2024-09-04

1,4-diaminobutanone and putrescine

1,4-diaminobutanone has been researched along with putrescine in 30 studies

Compound Research Comparison

Studies
(1,4-diaminobutanone)
Trials
(1,4-diaminobutanone)
Recent Studies (post-2010)
(1,4-diaminobutanone)
Studies
(putrescine)
Trials
(putrescine)
Recent Studies (post-2010) (putrescine)
32084,64327826

Protein Interaction Comparison

ProteinTaxonomy1,4-diaminobutanone (IC50)putrescine (IC50)
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAINHomo sapiens (human)0.2001
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAINHomo sapiens (human)0.2001
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAINHomo sapiens (human)0.2001
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAINHomo sapiens (human)0.2001

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19904 (13.33)18.7374
1990's10 (33.33)18.2507
2000's9 (30.00)29.6817
2010's7 (23.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McKinnon, IM; Stevens, L; Winther, M1
McKinnon, IM; Stevens, L1
Gil, ML; Lopez-Ribot, JL; Martinez, JP; Ruiz-Herrera, J; Sentandreu, R1
Cano, C; Herrera-Estrella, L; Ruiz-Herrera, J1
Calvo-Mendez, C; Martinez-Pacheco, M; Reyna, G; Rodriguez, G; Ruiz-Herrera, J1
Calvo-Mendez, C; Guevara-Olvera, L; Ruiz-Herrera, J1
Feistner, GJ1
Ruiz-Herrera, J1
Armstrong, SK; Brickman, TJ1
Ruiz-Herrera, J; San-Blas, F; San-Blas, G; Sorais, F1
Moreno, B; Ruiz-Herrera, J; San-Blas, F; San-Blas, G; Sorais, F1
Guzmán-de-Peña, D; Ruiz-Herrera, J1
Aguirre, J; Guzmán-de-Peña, D; Ruiz-Herrera, J1
Johnson, PJ; Martinez, MP; Reis, IA; Silva-Filho, FC; Vannier-Santos, MA; Yarlett, N1
Cole, GT; Guevara-Olvera, L; Hung, CY; Yu, JJ1
Kotzabasis, K; Langebartels, C; Lütz, C; Lütz-Meindl, U; Navakoudis, E1
Reyna-López, GE; Ruiz-Herrera, J1
Fukumatsu, M; Matsumoto, T; Mikami, T; Ogasawara, A; Ueno, Y; Watanabe, T1
Alderete, JF; Benchimol, M; Garcia, AF1
Menezes, D; Oliveira, MF; Valentim, C; Vannier-Santos, MA1
Fedotova, MV; Tkachenko, AG1
De Souza, W; Lanfredi-Rangel, A; Maia, C; Oliveira, MF; Santana-Anjos, KG; Vannier-Santos, MA1
de Mello, FG; Menezes, D; Oliveira, MF; Vannier-Santos, MA1
Alves, MJ; Bechara, EJ; Soares, CO1
Codd, R; Pakchung, AA; Soe, CZ1
Alves, MJ; Bechara, EJ; Colli, W; Soares, CO1
Bechara, EJ; Boiani, M; Marnett, LJ; Soares, CO1
Alvarez-Sánchez, ME; Arroyo, R; Carrillo-Tapia, E; Carvajal-Gamez, BI; Quintas-Granados, LI; Ramón-Luing, Lde L; Vázquez-Carrillo, LI1
Codd, R; Lay, PA; Levina, A; Soe, CZ; Telfer, TJ1
Alvarez-Sánchez, ME; Camacho-Nuez, M; Ponce-Regalado, MD; Puente-Rivera, J; Quintas-Granados, LI; Vázquez-Carrillo, LI; Villalobos-Osnaya, A1

Reviews

1 review(s) available for 1,4-diaminobutanone and putrescine

ArticleYear
The role of polyamines in fungal cell differentiation.
    Archives of medical research, 1993,Autumn, Volume: 24, Issue:3

    Topics: Cell Differentiation; Fungal Proteins; Fungi; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spores, Fungal

1993

Other Studies

29 other study(ies) available for 1,4-diaminobutanone and putrescine

ArticleYear
The effects of 1,4-diaminobutanone on polyamine synthesis in Aspergillus nidulans.
    FEBS letters, 1977, Mar-15, Volume: 75, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Amines; Aspergillus nidulans; Butanones; Enzyme Activation; Kinetics; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Structure-Activity Relationship

1977
The effect of 1,4-diaminobutanone on the stability of ornithine decarboxylase from Aspergillus nidulans.
    The Biochemical journal, 1977, Sep-15, Volume: 166, Issue:3

    Topics: Aspergillus nidulans; Butanones; Carboxy-Lyases; Chymotrypsin; Cycloheximide; Enzyme Activation; Half-Life; Ornithine Decarboxylase; Putrescine

1977
Inhibition of the dimorphic transition of Candida albicans by the ornithine decarboxylase inhibitor 1,4-diaminobutanone: alterations in the glycoprotein composition of the cell wall.
    Journal of general microbiology, 1990, Volume: 136, Issue:10

    Topics: Candida albicans; Cell Wall; Fungal Proteins; Membrane Glycoproteins; Ornithine Decarboxylase Inhibitors; Putrescine

1990
DNA methylation and polyamines in regulation of development of the fungus Mucor rouxii.
    Journal of bacteriology, 1988, Volume: 170, Issue:12

    Topics: Azacitidine; DNA, Fungal; Hydroxyurea; Methylation; Mucor; Polyamines; Putrescine; Spores, Fungal

1988
Inhibition of the yeast-mycelial transition and the phorogenesis of Mucorales by diamino butanone.
    Archives of microbiology, 1989, Volume: 151, Issue:1

    Topics: Cell Differentiation; Mucor; Mucorales; Ornithine Decarboxylase Inhibitors; Phycomyces; Polyamines; Putrescine

1989
The role of polyamine metabolism in dimorphism of Yarrowia lipolytica.
    Journal of general microbiology, 1993, Volume: 139, Issue:3

    Topics: Azacitidine; DNA, Fungal; Eflornithine; Methylation; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Saccharomycetales

1993
Metabolism of polyamines and basic amino acids in Erwinia amylovora: application of liquid chromatography/electrospray mass spectrometry to proferrioxamine precursor feeding and inhibition studies.
    Biological mass spectrometry, 1994, Volume: 23, Issue:12

    Topics: Amino Acids; Cell Division; Chromatography, Liquid; Dansyl Compounds; Deferoxamine; Erwinia; Hydroxylysine; Mass Spectrometry; Polyamines; Putrescine

1994
The ornithine decarboxylase gene odc is required for alcaligin siderophore biosynthesis in Bordetella spp.: putrescine is a precursor of alcaligin.
    Journal of bacteriology, 1996, Volume: 178, Issue:1

    Topics: Amino Acid Sequence; Base Sequence; Bordetella bronchiseptica; Cloning, Molecular; DNA Transposable Elements; Enzyme Inhibitors; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Hydroxamic Acids; Models, Chemical; Molecular Sequence Data; Mutagenesis, Insertional; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Restriction Mapping; Sequence Alignment; Sequence Analysis, DNA; Siderophores

1996
Ornithine decarboxylase in Paracoccidioides brasiliensis.
    Archives of microbiology, 1996, Volume: 165, Issue:5

    Topics: Enzyme Inhibitors; Hydrogen-Ion Concentration; Latin America; Mycoses; Ornithine Decarboxylase; Paracoccidioides; Putrescine

1996
Polyamines in growth and dimorphism of Paracoccidioides brasiliensis.
    Archives of microbiology, 1996, Volume: 166, Issue:6

    Topics: Ornithine Decarboxylase Inhibitors; Paracoccidioides; Putrescine; Spermidine

1996
Relationship between aflatoxin biosynthesis and sporulation in Aspergillus parasiticus.
    Fungal genetics and biology : FG & B, 1997, Volume: 21, Issue:2

    Topics: Aflatoxins; Aspergillus; Enzyme Inhibitors; Mutation; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spores, Fungal

1997
Correlation between the regulation of sterigmatocystin biosynthesis and asexual and sexual sporulation in Emericella nidulans.
    Antonie van Leeuwenhoek, 1998, Volume: 73, Issue:2

    Topics: Aspergillus nidulans; Culture Media; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Regulator; Light; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Spores, Fungal; Sterigmatocystin; Transcription Factors

1998
Inhibition of polyamine synthesis arrests trichomonad growth and induces destruction of hydrogenosomes.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:8

    Topics: Animals; Biogenic Polyamines; Chromatography, High Pressure Liquid; Culture Media; Microscopy, Electron; Movement; Organelles; Putrescine; Spermidine; Spermine; Tritrichomonas foetus

1999
Sequence, expression and functional analysis of the Coccidioides immitis ODC (ornithine decarboxylase) gene.
    Gene, 2000, Jan-25, Volume: 242, Issue:1-2

    Topics: Amino Acid Sequence; Base Sequence; Blotting, Southern; Coccidioides; DNA, Fungal; Escherichia coli; Gene Expression; Gene Expression Regulation, Developmental; Gene Expression Regulation, Fungal; Genes, Fungal; Molecular Sequence Data; Mutation; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Recombinant Fusion Proteins; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Transformation, Genetic

2000
Ozone impact on the photosynthetic apparatus and the protective role of polyamines.
    Biochimica et biophysica acta, 2003, May-02, Volume: 1621, Issue:2

    Topics: Biogenic Polyamines; Ozone; Photosynthesis; Putrescine

2003
Specificity of DNA methylation changes during fungal dimorphism and its relationship to polyamines.
    Current microbiology, 2004, Volume: 48, Issue:2

    Topics: DNA Fingerprinting; DNA Methylation; DNA, Fungal; Enzyme Inhibitors; Fungi; Mucor; Mycelium; Nucleic Acid Amplification Techniques; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Ustilago; Yarrowia

2004
Hyphae formation of Candida albicans is regulated by polyamines.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:6

    Topics: Candida albicans; Dose-Response Relationship, Drug; Hyphae; Polyamines; Putrescine

2004
Trichomonas vaginalis polyamine metabolism is linked to host cell adherence and cytotoxicity.
    Infection and immunity, 2005, Volume: 73, Issue:5

    Topics: Animals; Cell Adhesion; Cell Line; Epithelial Cells; Female; Humans; Polyamines; Putrescine; Trichomonas vaginalis; Vagina; Virulence

2005
Putrescine analogue cytotoxicity against Trypanosoma cruzi.
    Parasitology research, 2006, Volume: 98, Issue:2

    Topics: Animals; Microscopy, Electron, Transmission; Mitochondria; Oxidative Stress; Putrescine; Trypanosoma cruzi

2006
Dependence of protective functions of Escherichia coli polyamines on strength of stress caused by superoxide radicals.
    Biochemistry. Biokhimiia, 2007, Volume: 72, Issue:1

    Topics: Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Oxidative Stress; Polyamines; Putrescine; Regulon; Superoxides; Trans-Activators

2007
Effects of a putrescine analog on Giardia lamblia.
    Parasitology research, 2008, Volume: 103, Issue:2

    Topics: Animals; Giardia lamblia; Oxidative Stress; Polyamines; Putrescine; Trophozoites

2008
The putrescine analogue 1,4-diamino-2-butanone affects polyamine synthesis, transport, ultrastructure and intracellular survival in Leishmania amazonensis.
    Microbiology (Reading, England), 2008, Volume: 154, Issue:Pt 10

    Topics: Animals; Antiprotozoal Agents; Cell Proliferation; Cells, Cultured; Leishmania; Lipid Peroxidation; Macrophages; Mice; Microscopy, Electron, Transmission; Mitochondria; Ornithine Decarboxylase; Polyamines; Putrescine; Tetrazolium Salts; Thiazoles

2008
1,4-Diamino-2-butanone, a wide-spectrum microbicide, yields reactive species by metal-catalyzed oxidation.
    Free radical biology & medicine, 2011, Jun-15, Volume: 50, Issue:12

    Topics: Animals; Anti-Infective Agents; Cell Line; Cell Survival; Ferritins; Free Radicals; Haplorhini; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Metals; Oxygen Consumption; Polyamines; Putrescine; Reactive Oxygen Species; Superoxides; Transferrin

2011
Directing the biosynthesis of putrebactin or desferrioxamine B in Shewanella putrefaciens through the upstream inhibition of ornithine decarboxylase.
    Chemistry & biodiversity, 2012, Volume: 9, Issue:9

    Topics: Deferoxamine; Enzyme Inhibitors; Molecular Structure; Ornithine Decarboxylase Inhibitors; Putrescine; Shewanella putrefaciens; Siderophores; Spectrometry, Mass, Electrospray Ionization; Succinates

2012
1,4-Diamino-2-butanone, a putrescine analogue, promotes redox imbalance in Trypanosoma cruzi and mammalian cells.
    Archives of biochemistry and biophysics, 2012, Dec-15, Volume: 528, Issue:2

    Topics: Animals; Cell Line; Models, Biological; Oxidants; Oxidation-Reduction; Protozoan Proteins; Putrescine; Sulfhydryl Compounds; Superoxide Dismutase; Trypanocidal Agents; Trypanosoma cruzi

2012
Cytotoxicity of 1,4-diamino-2-butanone, a putrescine analogue, to RKO cells: mechanism and redox imbalance.
    Free radical research, 2013, Volume: 47, Issue:9

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Glutathione; Humans; Hydrogen Peroxide; Metabolic Networks and Pathways; Oxidation-Reduction; Polyamines; Putrescine; Reactive Oxygen Species; Superoxides

2013
Putrescine-dependent re-localization of TvCP39, a cysteine proteinase involved in Trichomonas vaginalis cytotoxicity.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Active Transport, Cell Nucleus; Blotting, Western; Cell Division; Cell Nucleus; Cysteine Proteases; Gene Expression; Microscopy, Confocal; Proteolysis; Protozoan Proteins; Putrescine; Reverse Transcriptase Polymerase Chain Reaction; Trichomonas vaginalis

2014
Simultaneous biosynthesis of putrebactin, avaroferrin and bisucaberin by Shewanella putrefaciens and characterisation of complexes with iron(III), molybdenum(VI) or chromium(V).
    Journal of inorganic biochemistry, 2016, Volume: 162

    Topics: Bacterial Proteins; Cadaverine; Chromium; Coordination Complexes; Diamines; Electron Spin Resonance Spectroscopy; Gene Expression; Hydroxamic Acids; Iron; Molybdenum; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Peptides, Cyclic; Putrescine; Shewanella putrefaciens; Succinates

2016
Proteomic profile approach of effect of putrescine depletion over Trichomonas vaginalis.
    Parasitology research, 2018, Volume: 117, Issue:5

    Topics: Animals; Biological Transport; Culture Media; Down-Regulation; Female; Proteome; Proteomics; Putrescine; Spermine; Trichomonas vaginalis; Vagina

2018