Page last updated: 2024-09-04

1,4-di(2'-thienyl)-1,4-butadione and pf 5901

1,4-di(2'-thienyl)-1,4-butadione has been researched along with pf 5901 in 1 studies

Compound Research Comparison

Studies
(1,4-di(2'-thienyl)-1,4-butadione)
Trials
(1,4-di(2'-thienyl)-1,4-butadione)
Recent Studies (post-2010)
(1,4-di(2'-thienyl)-1,4-butadione)
Studies
(pf 5901)
Trials
(pf 5901)
Recent Studies (post-2010) (pf 5901)
70184014

Protein Interaction Comparison

ProteinTaxonomy1,4-di(2'-thienyl)-1,4-butadione (IC50)pf 5901 (IC50)
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)1.65
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)0.776
Prostaglandin G/H synthase 1Homo sapiens (human)5.3
Prostaglandin G/H synthase 2Homo sapiens (human)5.3
Cysteinyl leukotriene receptor 1Homo sapiens (human)1.1

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1

Other Studies

1 other study(ies) available for 1,4-di(2'-thienyl)-1,4-butadione and pf 5901

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016