1,4-di(2'-thienyl)-1,4-butadione has been researched along with disulfiram in 1 studies
| Studies (1,4-di(2'-thienyl)-1,4-butadione) | Trials (1,4-di(2'-thienyl)-1,4-butadione) | Recent Studies (post-2010) (1,4-di(2'-thienyl)-1,4-butadione) | Studies (disulfiram) | Trials (disulfiram) | Recent Studies (post-2010) (disulfiram) |
|---|---|---|---|---|---|
| 7 | 0 | 1 | 3,776 | 175 | 723 |
| Protein | Taxonomy | 1,4-di(2'-thienyl)-1,4-butadione (IC50) | disulfiram (IC50) |
|---|---|---|---|
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 10.1 | |
| Spike glycoprotein | Betacoronavirus England 1 | 9.35 | |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | 9.35 | |
| type-1 angiotensin II receptor | Homo sapiens (human) | 6.637 | |
| perilipin-5 | Homo sapiens (human) | 1.622 | |
| perilipin-1 | Homo sapiens (human) | 6.959 | |
| apelin receptor | Homo sapiens (human) | 2.63 | |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | 4.2905 | |
| bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Mycobacterium tuberculosis H37Rv | 85.03 | |
| Transmembrane protease serine 2 | Homo sapiens (human) | 9.35 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Carbamate kinase | Giardia intestinalis | 0.6 | |
| Retinal dehydrogenase 1 | Homo sapiens (human) | 0.13 | |
| Aldehyde dehydrogenase, mitochondrial | Homo sapiens (human) | 3.4 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 4 | |
| Procathepsin L | Homo sapiens (human) | 9.35 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 4.904 | |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | 1.3756 | |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
| Replicase polyprotein 1ab | Human coronavirus 229E | 9.35 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.356 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.9171 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.356 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 3.218 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 2.158 | |
| D(4) dopamine receptor | Homo sapiens (human) | 3.15 | |
| C-X-C chemokine receptor type 2 | Homo sapiens (human) | 6.013 | |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | 1.51 | |
| Protein-lysine 6-oxidase | Homo sapiens (human) | 0.32 | |
| Lysine-specific demethylase 5A | Homo sapiens (human) | 10 | |
| Caspase-1 | Homo sapiens (human) | 1.8 | |
| Mu-type opioid receptor | Homo sapiens (human) | 3.511 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.084 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 6.103 | |
| C-C chemokine receptor type 2 | Homo sapiens (human) | 2.468 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.356 | |
| C-C chemokine receptor type 4 | Homo sapiens (human) | 8.395 | |
| Gasdermin-D | Homo sapiens (human) | 0.4 | |
| Lysyl oxidase homolog 3 | Homo sapiens (human) | 0.093 | |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | 9.35 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 4.637 | |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | 3 | |
| Lysyl oxidase homolog 4 | Homo sapiens (human) | 0.059 | |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | 0.6 | |
| Monoglyceride lipase | Homo sapiens (human) | 0.8095 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 9.35 | |
| Gasdermin-D | Mus musculus (house mouse) | 0.4 | |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | 1.6 | |
| Lysyl oxidase homolog 2 | Homo sapiens (human) | 0.15 | |
| large T antigen | Betapolyomavirus macacae | 10.73 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
1 other study(ies) available for 1,4-di(2'-thienyl)-1,4-butadione and disulfiram
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |