1,4-di(2'-thienyl)-1,4-butadione and aa 861

1,4-di(2'-thienyl)-1,4-butadione has been researched along with aa 861 in 1 studies

Compound Research Comparison

Studies (1,4-di(2'-thienyl)-1,4-butadione)	Trials (1,4-di(2'-thienyl)-1,4-butadione)	Recent Studies (post-2010) (1,4-di(2'-thienyl)-1,4-butadione)	Studies (aa 861)	Trials (aa 861)	Recent Studies (post-2010) (aa 861)
7	0	1	290	2	34

Protein Interaction Comparison

Protein	Taxonomy	aa 861 (IC50)
Polyunsaturated fatty acid 5-lipoxygenase	Homo sapiens (human)	1.7
Polyunsaturated fatty acid 5-lipoxygenase	Rattus norvegicus (Norway rat)	1.045
Polyunsaturated fatty acid 5-lipoxygenase	Mus musculus (house mouse)	0.032
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	Cavia porcellus (domestic guinea pig)	1.7
M17 leucyl aminopeptidase	Plasmodium falciparum 3D7	53.45

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1

Other Studies

1 other study(ies) available for 1,4-di(2'-thienyl)-1,4-butadione and aa 861

Article	Year
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016

Article

Year

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.

PloS one, 2016, Volume: 11, Issue:10

Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016