1,4-bis(4-methoxyphenyl)-3-(3-phenylpropyl)-2-azetidinone has been researched along with gemfibrozil in 1 studies
| Studies (1,4-bis(4-methoxyphenyl)-3-(3-phenylpropyl)-2-azetidinone) | Trials (1,4-bis(4-methoxyphenyl)-3-(3-phenylpropyl)-2-azetidinone) | Recent Studies (post-2010) (1,4-bis(4-methoxyphenyl)-3-(3-phenylpropyl)-2-azetidinone) | Studies (gemfibrozil) | Trials (gemfibrozil) | Recent Studies (post-2010) (gemfibrozil) |
|---|---|---|---|---|---|
| 23 | 1 | 0 | 1,483 | 359 | 297 |
| Protein | Taxonomy | 1,4-bis(4-methoxyphenyl)-3-(3-phenylpropyl)-2-azetidinone (IC50) | gemfibrozil (IC50) |
|---|---|---|---|
| Cytochrome P450 2C8 | Homo sapiens (human) | 4.1 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 7.0795 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 4.0738 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afonso, A; Burnett, DA; Clader, JW; Davis, HR; Huynh, T; Rosenblum, SB; Yumibe, N | 1 |
1 other study(ies) available for 1,4-bis(4-methoxyphenyl)-3-(3-phenylpropyl)-2-azetidinone and gemfibrozil
| Article | Year |
|---|---|
Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4 -hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption.
Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Cricetinae; Drug Design; Ezetimibe; Liver; Structure-Activity Relationship | 1998 |