Compounds > 1,4-bis(2-(3,5-dichloropyridyloxy))benzene
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1,4-bis(2-(3,5-dichloropyridyloxy))benzene and androstan-3-ol

1,4-bis(2-(3,5-dichloropyridyloxy))benzene has been researched along with androstan-3-ol in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moore, DD; Pissios, P; Schuetz, EG; Tzameli, I1
Cai, Y; Campwala, KH; French, SW; Han, G; Konishi, T; Wan, YJ1
Dussault, I; Fan, M; Forman, BM; Hollister, K; Lin, M; Sherman, MA; Termini, J1
Chua, SS; Huang, W; Moore, DD; Wei, P; Zhang, J1
Andersin, T; Carlberg, C; Väisänen, S1
Columbano, A; Concas, D; Cossu, C; Ledda-Columbano, GM; Molotzu, F; Pibiri, M; Simbula, G1
Baptissart, M; Baron, S; Beaudoin, C; Caira, F; de Haze, A; Martinot, E; Rouaisnel, B; Saru, JP; Sèdes, L; Vaz, F; Véga, A; Volle, DH1

Other Studies

7 other study(ies) available for 1,4-bis(2-(3,5-dichloropyridyloxy))benzene and androstan-3-ol

ArticleYear
The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR.
    Molecular and cellular biology, 2000, Volume: 20, Issue:9

    Topics: Amino Acid Sequence; Androstanols; Animals; Binding Sites; Blotting, Western; Cell Line; Constitutive Androstane Receptor; Dose-Response Relationship, Drug; Glutathione Transferase; Humans; Mice; Molecular Sequence Data; Mutagenesis; Plasmids; Protein Structure, Tertiary; Pyridines; Receptors, Cytoplasmic and Nuclear; Sequence Homology, Amino Acid; Trans-Activators; Transcription Factors; Transfection

2000
The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2002, Volume: 15, Issue:1

    Topics: Androstanols; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Gene Expression Regulation; Hepatocytes; Hepatomegaly; Male; Mice; Mice, Knockout; Pyridines; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Signal Transduction; Steroid Hydroxylases; Transcription Factors; Xenobiotics

2002
A structural model of the constitutive androstane receptor defines novel interactions that mediate ligand-independent activity.
    Molecular and cellular biology, 2002, Volume: 22, Issue:15

    Topics: Androstanols; Animals; Binding, Competitive; Cell Line; Constitutive Androstane Receptor; Ligands; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Pyridines; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship; Transcription Factors

2002
Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR.
    Science (New York, N.Y.), 2002, Oct-11, Volume: 298, Issue:5592

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Androstanols; Animals; Aryl Hydrocarbon Hydroxylases; Benzoquinones; Constitutive Androstane Receptor; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Glutathione; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Imines; Isoenzymes; Liver; Mice; Mice, Knockout; Mice, Transgenic; Oxidoreductases, N-Demethylating; Phenobarbital; Pyridines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Time Factors; Transcription Factors

2002
The critical role of carboxy-terminal amino acids in ligand-dependent and -independent transactivation of the constitutive androstane receptor.
    Molecular endocrinology (Baltimore, Md.), 2003, Volume: 17, Issue:2

    Topics: Amino Acids; Androstanols; Animals; Calcitriol; Cells, Cultured; Constitutive Androstane Receptor; Cysteine; Disulfides; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Mice; Mutagenesis, Site-Directed; Nuclear Receptor Coactivator 2; Peptide Fragments; Protein Structure, Tertiary; Pyridines; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Response Elements; Retinoid X Receptors; Transcription Factors; Transcriptional Activation

2003
Sex difference in the proliferative response of mouse hepatocytes to treatment with the CAR ligand, TCPOBOP.
    Carcinogenesis, 2003, Volume: 24, Issue:6

    Topics: Androstanols; Animals; Aryl Hydrocarbon Hydroxylases; Cell Division; Constitutive Androstane Receptor; Cyclin D1; Cytochrome P450 Family 2; Female; Hepatocytes; Male; Mice; Pyridines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Sex Characteristics; Steroid Hydroxylases; Transcription Factors

2003
Bile acid homeostasis controls CAR signaling pathways in mouse testis through FXRalpha.
    Scientific reports, 2017, 02-09, Volume: 7

    Topics: Androstanols; Animals; Bile Acids and Salts; Constitutive Androstane Receptor; Gene Expression Regulation; Homeostasis; Liver; Male; Mice; Mice, Knockout; Pyridines; Receptors, Cytoplasmic and Nuclear; Reproduction; Signal Transduction; Spermatozoa; Testis

2017