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1,4-androstadiene-3,17-dione and formestane

1,4-androstadiene-3,17-dione has been researched along with formestane in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cole, PA; Robinson, CH1
Gynther, J; Honkakoski, P; Jyrkkärinne, J; Mäkinen, J; Poso, A; Savolainen, H1
Bellavance, E; Luu-The, V; Poirier, D1
Barmade, MA; Murumkar, PR; Tamboli, RS; Yadav, MR1
Covey, DF; Hood, WF1

Reviews

2 review(s) available for 1,4-androstadiene-3,17-dione and formestane

ArticleYear
Mechanism and inhibition of cytochrome P-450 aromatase.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:11

    Topics: Affinity Labels; Aromatase; Aromatase Inhibitors; Binding, Competitive; Humans; Molecular Structure; Photochemistry

1990
Developing steroidal aromatase inhibitors-an effective armament to win the battle against breast cancer.
    European journal of medicinal chemistry, 2015, Nov-13, Volume: 105

    Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Female; Humans; Models, Molecular; Molecular Structure

2015

Other Studies

3 other study(ies) available for 1,4-androstadiene-3,17-dione and formestane

ArticleYear
Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor.
    Journal of medicinal chemistry, 2003, Oct-23, Volume: 46, Issue:22

    Topics: Animals; Cell Line; Constitutive Androstane Receptor; Histone Acetyltransferases; Humans; Mice; Models, Molecular; Mutation; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Protein Structure, Secondary; Quantitative Structure-Activity Relationship; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Repressor Proteins; Steroids; Transcription Factors; Two-Hybrid System Techniques; Yeasts

2003
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
A new hypothesis based on suicide substrate inhibitor studies for the mechanism of action of aromatase.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Androstadienes; Androstatrienes; Androstenedione; Androstenes; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy; Structure-Activity Relationship; Testolactone

1982