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1,4-androstadiene-3,17-dione and androstenedione

1,4-androstadiene-3,17-dione has been researched along with androstenedione in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19903 (8.11)18.7374
1990's6 (16.22)18.2507
2000's11 (29.73)29.6817
2010's15 (40.54)24.3611
2020's2 (5.41)2.80

Authors

AuthorsStudies
Cole, PA; Robinson, CH1
Gynther, J; Honkakoski, P; Jyrkkärinne, J; Mäkinen, J; Poso, A; Savolainen, H1
Al-Aboudi, A; Choudhary, MI; Khalid, A; Naz, Q; Odeh, H1
Barmade, MA; Murumkar, PR; Tamboli, RS; Yadav, MR1
Bian, EP; Wang, Y; Zhang, LQ1
Dutta, RK; Roy, MK; Singh, HD1
Kirk, DN; Latif, S; Smith, KE1
Leppik, RA; Sinden, DJ1
Covey, DF; Hood, WF1
Goff, D; Pfeifer, D; Smith, M; Zahnley, J1
Choi, KP; Molnár, I; Murooka, Y1
Numazawa, M; Oshibe, M; Tachibana, M; Yamaguchi, S1
Dogra, N; Qazi, GN1
Korycka-Machała, M; Lisowska, K; Rumijowska-Galewicz, A; Sedlacze, L; Ziolkowskit, A1
Becerra, J; Mondaca, MA; Silva, M; Vidal, M1
Donova, MV; Dovbnya, DV; Gulevskaya, SA; Puntus, IF1
Arioli, F; Biondi, PA; Chiesa, LM; Fracchiolla, ML; Pompa, G1
Arioli, F; Bassini, AL; Biondi, PA; Fracchiolla, ML; Pompa, G; Rossi, CA; Stella, S1
Donova, MV; Dovbnya, DV; Gulevskaya, SA; Nikolayeva, VM; Suzina, NE1
Bhardwaj, V; Gupta, RK; Khajuria, RK; Mehta, P; Qazi, GN; Sharma, P; Somal, P1
Bekaert, K; Bussche, JV; De Brabander, HF; Janssen, CR; Noppe, H; Thas, O; Vanhaecke, L; Verheyden, K; Wille, K1
Numazawa, M; Takahashi, M; Yamashita, K1
Fan, SY; Wang, FQ; Wei, DZ; Wei, W1
Drzyzga, O; Fernández de las Heras, L; María Navarro Llorens, J; Perera, J; van der Geize, R1
Li, H; Rao, Z; Shao, M; Xu, M; Xu, Z; Yang, T; Zhang, W; Zhang, X1
Fabregat, A; Garrostas, L; Marcos, J; Pozo, OJ; Segura, J; Ventura, R1
Ashapkin, VV; Bragin, EY; Donova, MV; Dovbnya, DV; Egorova, OV; Ivashina, TV; Malakho, SG; Pekov, YA; Schelkunov, MI; Shtratnikova, VY; Sokolov, SL1
Qin, N; Shen, Y; Su, L; Wang, M; Wang, Y; Xie, R1
Bailly-Chouriberry, L; Bonnaire, Y; Decloedt, AI; Garcia, P; Popot, MA; Vanden Bussche, J; Vanhaecke, L1
Yin, Y1
Li, H; Rao, Z; Shao, M; Xu, M; Xu, Z; Yang, S; Yang, T; Zhang, X1
Liu, M; Tao, XY; Wang, FQ; Wei, DZ; Zhu, ZT1
Saraphanchotiwitthaya, A; Sripalakit, P1
Felpeto-Santero, C; Fernández-Cabezón, L; Galán, B; García, JL; García-Fernández, J; Martínez, I1
Bajaj, A; Prakash, S1
Donova, M; Kazantsev, A; Kollerov, V; Shutov, A1
Liu, C; Osire, T; Rao, Z; Shao, M; Xu, Z1

Reviews

2 review(s) available for 1,4-androstadiene-3,17-dione and androstenedione

ArticleYear
Mechanism and inhibition of cytochrome P-450 aromatase.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:11

    Topics: Affinity Labels; Aromatase; Aromatase Inhibitors; Binding, Competitive; Humans; Molecular Structure; Photochemistry

1990
Developing steroidal aromatase inhibitors-an effective armament to win the battle against breast cancer.
    European journal of medicinal chemistry, 2015, Nov-13, Volume: 105

    Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Female; Humans; Models, Molecular; Molecular Structure

2015

Trials

1 trial(s) available for 1,4-androstadiene-3,17-dione and androstenedione

ArticleYear
Excretion of endogenous boldione in human urine: influence of phytosterol consumption.
    The Journal of steroid biochemistry and molecular biology, 2009, Volume: 117, Issue:1-3

    Topics: Adult; Anabolic Agents; Androstadienes; Androstenedione; Biotransformation; Epitestosterone; Female; Food Analysis; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Molecular Structure; Phytosterols; Tandem Mass Spectrometry; Testosterone; Young Adult

2009

Other Studies

34 other study(ies) available for 1,4-androstadiene-3,17-dione and androstenedione

ArticleYear
Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor.
    Journal of medicinal chemistry, 2003, Oct-23, Volume: 46, Issue:22

    Topics: Animals; Cell Line; Constitutive Androstane Receptor; Histone Acetyltransferases; Humans; Mice; Models, Molecular; Mutation; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Protein Structure, Secondary; Quantitative Structure-Activity Relationship; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Repressor Proteins; Steroids; Transcription Factors; Two-Hybrid System Techniques; Yeasts

2003
Butyrylcholinesterase inhibitory activity of testosterone and some of its metabolites.
    Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:2

    Topics: Androstenedione; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Enzyme Inhibitors; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Kinetics; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Testosterone

2009
[Side chain cleavage of sterols by Mycobacterium sp. M12].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:12

    Topics: Androstadienes; Androstenedione; Cholesterol; Etiocholanolone; Mycobacterium; Sitosterols

1992
Metabolic blocks in the degradation of beta-sitosterol by a plasmid-cured strain of Arthrobacter oxydans.
    Journal of basic microbiology, 1992, Volume: 32, Issue:3

    Topics: Androstadienes; Androstenedione; Arthrobacter; Biodegradation, Environmental; Cholestenones; Plasmids; Sitosterols; Species Specificity

1992
Microbial transformation of steroids--II. Transformations of progesterone, testosterone and androstenedione by Phycomyces blakesleeanus.
    Journal of steroid biochemistry, 1989, Volume: 32, Issue:3

    Topics: Androstadienes; Androstenedione; Biotransformation; Chromatography, High Pressure Liquid; Hydroxylation; Hydroxyprogesterones; Hydroxytestosterones; Magnetic Resonance Spectroscopy; Mucorales; Phycomyces; Progesterone; Testosterone

1989
Pseudomonas mutant strains that accumulate androstane and seco-androstane intermediates from bile acids.
    The Biochemical journal, 1987, Apr-01, Volume: 243, Issue:1

    Topics: Androstadienes; Androstanes; Androstatrienes; Androstenedione; Bile Acids and Salts; Cresols; DNA Transposable Elements; Mutation; Pseudomonas; Secosteroids

1987
A new hypothesis based on suicide substrate inhibitor studies for the mechanism of action of aromatase.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Androstadienes; Androstatrienes; Androstenedione; Androstenes; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy; Structure-Activity Relationship; Testolactone

1982
Growth and cholesterol oxidation by Mycobacterium species in Tween 80 medium.
    Applied and environmental microbiology, 1993, Volume: 59, Issue:5

    Topics: Androstadienes; Androstenedione; Biotransformation; Cholesterol; Cholesterol Oxidase; Culture Media; Kinetics; Mycobacterium; Oxidation-Reduction; Polysorbates; Temperature

1993
Secretory overproduction of Arthrobacter simplex 3-ketosteroid delta 1-dehydrogenase by Streptomyces lividans with a multi-copy shuttle vector.
    Applied microbiology and biotechnology, 1995, Volume: 43, Issue:6

    Topics: Androstadienes; Androstenedione; Arthrobacter; Bacterial Proteins; Chromatography, High Pressure Liquid; Cloning, Molecular; Culture Media, Conditioned; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Oxidoreductases; Recombinant Fusion Proteins; Sequence Deletion; Streptomyces

1995
Time-dependent inactivation of aromatase by 6-alkylandrosta-1,4-diene-3,17-diones. Effects of length and configuration of 6-alkyl group.
    Journal of medicinal chemistry, 1996, Mar-01, Volume: 39, Issue:5

    Topics: Alkylation; Androstadienes; Androstenedione; Aromatase; Aromatase Inhibitors; Enzyme Inhibitors; Female; Humans; Kinetics; Microsomes; Models, Molecular; Molecular Conformation; Molecular Structure; NADP; Placenta; Structure-Activity Relationship; Tritium

1996
Steroid biotransformation by different strains of Micrococcus sp.
    Folia microbiologica, 2001, Volume: 46, Issue:1

    Topics: Androstadienes; Androstenedione; Animals; Biotransformation; Cholesterol; Fatty Acids; Micrococcus; Plasmids; Rats

2001
Enhancement of beta-sitosterol transformation in Mycobacterium vaccae with increased cell wall permeability.
    Acta microbiologica Polonica, 2001, Volume: 50, Issue:2

    Topics: Androstadienes; Androstenedione; Biotransformation; Cell Membrane Permeability; Cell Wall; Fatty Acids; Glycine; Mycobacterium; Protamines; Sitosterols

2001
Selection of Mycobacterium sp. strains with capacity to biotransform high concentrations of beta-sitosterol.
    Applied microbiology and biotechnology, 2001, Volume: 57, Issue:3

    Topics: Androstadienes; Androstenedione; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Mycobacterium; Nuclear Magnetic Resonance, Biomolecular; Sitosterols

2001
Mycobacterium sp. mutant strain producing 9alpha-hydroxyandrostenedione from sitosterol.
    Applied microbiology and biotechnology, 2005, Volume: 67, Issue:5

    Topics: Androstadienes; Androstenedione; Biotransformation; Molecular Structure; Mutagenesis; Mycobacterium; Oxidoreductases; Selection, Genetic; Sitosterols

2005
ADD, AED, alpha-boldenone and epitestosterone neo formation in calf faeces: preliminary results.
    Veterinary research communications, 2005, Volume: 29 Suppl 2

    Topics: Androstadienes; Androstenedione; Animals; Cattle; Chromatography, High Pressure Liquid; Epitestosterone; Feces; Mass Spectrometry; Testosterone

2005
Neoformation of boldenone and related steroids in faeces of veal calves.
    Food additives and contaminants, 2006, Volume: 23, Issue:2

    Topics: Anabolic Agents; Androgens; Androstadienes; Androstenedione; Animals; Cattle; Epitestosterone; Feces; Gas Chromatography-Mass Spectrometry; Rectum; Testosterone

2006
Methyl-beta-cyclodextrin alters growth, activity and cell envelope features of sterol-transforming mycobacteria.
    Microbiology (Reading, England), 2007, Volume: 153, Issue:Pt 6

    Topics: 3-Hydroxysteroid Dehydrogenases; Androstadienes; Androstenedione; Bacterial Adhesion; Bacterial Proteins; beta-Cyclodextrins; Carbohydrates; Cell Wall; Cryoelectron Microscopy; Glycerol; Growth Substances; Lipids; Microscopy, Electron, Transmission; Mycobacterium; Polysaccharides, Bacterial

2007
Development of a rapid normal-phase LC-positive ion APCI-MS method for simultaneous detection and quantitation of cholesterol, androst-4-ene-3,1 7-dione, and androsta-1,4-diene-3,17-dione.
    Journal of chromatographic science, 2007, Volume: 45, Issue:8

    Topics: Androstadienes; Androstenedione; Atmospheric Pressure; Cholesterol; Mass Spectrometry; Reference Standards; Spectrophotometry, Ultraviolet

2007
Probing the binding pocket of the active site of aromatase with 2-phenylaliphatic androsta-1,4-diene-3,17-dione steroids.
    Steroids, 2010, Volume: 75, Issue:4-5

    Topics: Androstadienes; Androstenedione; Aromatase; Aromatase Inhibitors; Catalytic Domain; Enzyme Activation; Humans; Kinetics; Models, Molecular; Substrate Specificity; Time Factors

2010
Inactivation and augmentation of the primary 3-ketosteroid-{delta}1- dehydrogenase in Mycobacterium neoaurum NwIB-01: biotransformation of soybean phytosterols to 4-androstene- 3,17-dione or 1,4-androstadiene-3,17-dione.
    Applied and environmental microbiology, 2010, Volume: 76, Issue:13

    Topics: Amino Acid Sequence; Androstadienes; Androstenedione; Biotechnology; Cloning, Molecular; Gene Deletion; Genetic Engineering; Glycine max; Molecular Sequence Data; Mycobacterium; Oxidoreductases; Phytosterols; Polymerase Chain Reaction

2010
Molecular characterization of three 3-ketosteroid-Δ(1)-dehydrogenase isoenzymes of Rhodococcus ruber strain Chol-4.
    The Journal of steroid biochemistry and molecular biology, 2012, Volume: 132, Issue:3-5

    Topics: Androstadienes; Androstenedione; Cholesterol; Culture Media; Gene Deletion; Genetic Complementation Test; Genome, Bacterial; Isoenzymes; Molecular Sequence Data; Oxidoreductases; Rhodococcus

2012
Bioconversion of 4-androstene-3,17-dione to androst-1,4-diene-3,17-dione by recombinant Bacillus subtilis expressing ksdd gene encoding 3-ketosteroid-Δ1-dehydrogenase from Mycobacterium neoaurum JC-12.
    The Journal of steroid biochemistry and molecular biology, 2013, Volume: 135

    Topics: Androstadienes; Androstenedione; Bacillus subtilis; Base Sequence; Biocatalysis; Gene Expression; Genetic Vectors; Molecular Sequence Data; Nontuberculous Mycobacteria; Oxidoreductases; Phylogeny; Plasmids; Recombinant Proteins; Sequence Analysis, DNA

2013
Evaluation of urinary excretion of androgens conjugated to cysteine in human pregnancy by mass spectrometry.
    The Journal of steroid biochemistry and molecular biology, 2014, Volume: 139

    Topics: Adult; Androgens; Androstadienes; Androstenedione; Cysteine; Dehydroepiandrosterone; Dihydrotestosterone; Doping in Sports; Estrogens; Female; Gas Chromatography-Mass Spectrometry; Humans; Longitudinal Studies; Pregnancy; Reference Standards; Reference Values; Tandem Mass Spectrometry; Testosterone

2014
Comparative analysis of genes encoding key steroid core oxidation enzymes in fast-growing Mycobacterium spp. strains.
    The Journal of steroid biochemistry and molecular biology, 2013, Volume: 138

    Topics: Androstadienes; Androstenedione; Bacterial Proteins; Mixed Function Oxygenases; Mycobacterium; Oxidoreductases; Phytosterols

2013
Genetic differences in ksdD influence on the ADD/AD ratio of Mycobacterium neoaurum.
    Journal of industrial microbiology & biotechnology, 2015, Volume: 42, Issue:4

    Topics: Androstadienes; Androstenedione; Biocatalysis; Nontuberculous Mycobacteria; Oxidoreductases; Rhodococcus

2015
In vitro simulation of the equine hindgut as a tool to study the influence of phytosterol consumption on the excretion of anabolic-androgenic steroids in horses.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 152

    Topics: Amino Acids; Anabolic Agents; Androgens; Androstadienes; Androstenedione; Animals; Chromatography, High Pressure Liquid; Dietary Carbohydrates; Digestion; Fatty Acids, Volatile; Female; Horses; Male; Mycobacterium; Phytosterols; Steroids; Tandem Mass Spectrometry; Testosterone

2015
Effects of Different Carbon Sources on Growth, Membrane Permeability, β-Sitosterol Consumption, Androstadienedione and Androstenedione Production by Mycobacterium neoaurum.
    Interdisciplinary sciences, computational life sciences, 2016, Volume: 8, Issue:1

    Topics: Androstadienes; Androstenedione; Carbon; Cell Membrane Permeability; Cell Wall; Hydrophobic and Hydrophilic Interactions; Lipids; Mycobacterium; Sitosterols

2016
A mutant form of 3-ketosteroid-Δ(1)-dehydrogenase gives altered androst-1,4-diene-3, 17-dione/androst-4-ene-3,17-dione molar ratios in steroid biotransformations by Mycobacterium neoaurum ST-095.
    Journal of industrial microbiology & biotechnology, 2016, Volume: 43, Issue:5

    Topics: Androstadienes; Androstenedione; Bacillus subtilis; Biotransformation; Hydrogenation; Mutant Proteins; Mycobacterium; Nontuberculous Mycobacteria; Oxidoreductases; Phytosterols

2016
RNA-Seq analysis uncovers non-coding small RNA system of Mycobacterium neoaurum in the metabolism of sterols to accumulate steroid intermediates.
    Microbial cell factories, 2016, Apr-25, Volume: 15

    Topics: Androstadienes; Androstenedione; Gene Expression Regulation, Bacterial; Gene Regulatory Networks; Metabolic Networks and Pathways; Mycobacterium; RNA, Small Untranslated; Sequence Analysis, RNA; Steroids; Sterols; Transcriptome

2016
Production of 4-androstene-3,17-dione and 1,4-androstadiene-3,17-dione from rice germ and wheat germ extracts by Mycobacterium sp.
    Biotechnology letters, 2016, Volume: 38, Issue:9

    Topics: Androstadienes; Androstenedione; Mycobacterium; Oryza; Plant Extracts; Triticum

2016
Bioconversion of Phytosterols into Androstadienedione by Mycobacterium smegmatis CECT 8331.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1645

    Topics: Androstadienes; Androstenedione; Biotechnology; Biotransformation; Fermentation; Mycobacterium smegmatis; Phytosterols

2017
Process for Biotransformation of Androsta-4-ene-3, 17-Dione (4-AD) to Androsta-1,4-Diene-3,17-Dione (ADD).
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1645

    Topics: Androstadienes; Androstenedione; Bacteria; Biotransformation; Carbon; Estradiol; Estrone; Metabolic Engineering

2017
Biotransformation of androstenedione and androstadienedione by selected Ascomycota and Zygomycota fungal strains.
    Phytochemistry, 2020, Volume: 169

    Topics: Androstadienes; Androstenedione; Biotransformation; Fungi; Molecular Conformation

2020
Identification of bottlenecks in 4-androstene-3,17-dione/1,4-androstadiene-3,17-dione synthesis by Mycobacterium neoaurum JC-12 through comparative proteomics.
    Journal of bioscience and bioengineering, 2021, Volume: 131, Issue:3

    Topics: Androstadienes; Androstenedione; Mycobacteriaceae; Phytosterols; Proteomics

2021