Page last updated: 2024-08-24

1,3-oxathiolane and thiophenes

1,3-oxathiolane has been researched along with thiophenes in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's3 (25.00)18.2507
2000's1 (8.33)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Bekemeier, H; Köster, D1
Gualtieri, F; Romanelli, MN; Teodori, E1
Angeli, P; Brasili, L; Giannella, M; Gualtieri, F; Picchio, MT; Teodori, E1
Angeli, P; Dei, S; Gualtieri, F; Marucci, G; Matucci, R; Romanelli, MN; Scappecchi, S; Teodori, E1
Alves, AJ; Beach, JW; Chu, CK; Jeong, LS; Kim, HO; Mathis, R; McMillan, A; Nampalli, S; Schinazi, RF; Shanmuganathan, K1
Cheng, YC; Dutschman, GE; Gullen, EA; Lin, TS; Liu, MC; Luo, MZ; Mozdziesz, DE; Sartorelli, AC1
Castilla, J; Castillón, S; Díaz, Y; Marín, I; Matheu, MI1
Alajarin, M; Bonillo, B; Sanchez-Andrada, P; Vidal, A1
Barbas, CF; Lamb, BM1
Hu, L; Ramström, O; Ren, Y1
Chada, S; Mandala, D; Watts, P1
Ji, MS; Kim, JH; Kim, JS; Won, M1

Other Studies

12 other study(ies) available for 1,3-oxathiolane and thiophenes

ArticleYear
[The pharmacology of some 1,3-dioxolanes, 1,3-oxathiolanes and 1,3-dithiolanes].
    Die Pharmazie, 1976, Volume: 31, Issue:5

    Topics: Animals; Anticonvulsants; Cats; Dioxolanes; Dioxoles; Guinea Pigs; Heterocyclic Compounds; Hexobarbital; In Vitro Techniques; Lethal Dose 50; Mice; Motor Activity; Muscle Contraction; Rats; Reflex; Sleep; Thiophenes; Time Factors

1976
Eudismic analysis of a series of muscarinic ligands carrying a 1,3-oxathiolane nucleus.
    Chirality, 1990, Volume: 2, Issue:2

    Topics: Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Heterocyclic Compounds; In Vitro Techniques; Molecular Conformation; Myocardium; Parasympathomimetics; Receptors, Muscarinic; Regression Analysis; Stereoisomerism; Thiophenes

1990
Chiral muscarinic agonists possessing a 1,3-oxathiolane nucleus: enantio- and tissue-selectivity on isolated preparations of guinea-pig ileum and atria and of rat urinary bladder.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:3

    Topics: Animals; Binding, Competitive; Carbachol; Guinea Pigs; Heart; Heterocyclic Compounds; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Receptors, Muscarinic; Stereoisomerism; Thiophenes; Urinary Bladder

1988
1,3-oxathiolane muscarinic ligands modified at the cationic head.
    Farmaco (Societa chimica italiana : 1989), 1994, Volume: 49, Issue:5

    Topics: Amidines; Animals; Blood-Brain Barrier; Cations; Guinea Pigs; Heterocyclic Compounds; In Vitro Techniques; Ligands; Muscle, Smooth; Rabbits; Receptors, Muscarinic; Thiophenes

1994
Asymmetric synthesis and biological evaluation of beta-L-(2R,5S)- and alpha-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents.
    Journal of medicinal chemistry, 1993, Jan-22, Volume: 36, Issue:2

    Topics: Antiviral Agents; Blood; Cells, Cultured; Heterocyclic Compounds; HIV-1; Humans; Magnetic Resonance Spectroscopy; Purine Nucleosides; Pyrimidine Nucleosides; Structure-Activity Relationship; Thiophenes

1993
Synthesis and biological evaluation of 1,3-oxathiolane 5-azapyrimidine, 6-azapyrimidine, and fluorosubstituted 3-deazapyrimidine nucleosides.
    Nucleosides, nucleotides & nucleic acids, 2000, Volume: 19, Issue:3

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Aza Compounds; Azauridine; Glycosylation; Hepatitis B virus; Heterocyclic Compounds; HIV-1; Humans; Pyrimidine Nucleosides; Thiophenes; Tumor Cells, Cultured

2000
Short and general procedure for synthesizing cis-1,2-fused 1,3-oxathiolan-, 1,3-oxaselenolan-, and 1,3-oxazolidin-2-imine carbohydrate derivatives.
    The Journal of organic chemistry, 2010, Jan-15, Volume: 75, Issue:2

    Topics: Carbohydrates; Imines; Magnetic Resonance Spectroscopy; Molecular Structure; Oxazoles; Selenium Compounds; Thiophenes

2010
Tandem 1,5-hydride shift/1,5-S,N-cyclization with ethylene extrusion of 1,3-oxathiolane-substituted ketenimines and carbodiimides. An experimental and computational study.
    The Journal of organic chemistry, 2010, Jun-04, Volume: 75, Issue:11

    Topics: Carbodiimides; Cyclization; Ethylenes; Heterocyclic Compounds; Hot Temperature; Imines; Ketones; Models, Chemical; Thiazoles; Thiophenes

2010
Selective arylthiolane deprotection by singlet oxygen: a promising tool for sensors and prodrugs.
    Chemical communications (Cambridge, England), 2015, Feb-21, Volume: 51, Issue:15

    Topics: Doxorubicin; Heterocyclic Compounds; Ketones; Light; Methylene Blue; Photosensitizing Agents; Prodrugs; Reactive Oxygen Species; Rose Bengal; Thiophenes

2015
Chirality Control in Enzyme-Catalyzed Dynamic Kinetic Resolution of 1,3-Oxathiolanes.
    The Journal of organic chemistry, 2015, Aug-21, Volume: 80, Issue:16

    Topics: Catalysis; Chromatography, High Pressure Liquid; Kinetics; Lamivudine; Magnetic Resonance Spectroscopy; Organic Chemistry Phenomena; Solvents; Stereoisomerism; Thiophenes

2015
Semi-continuous multi-step synthesis of lamivudine.
    Organic & biomolecular chemistry, 2017, Apr-18, Volume: 15, Issue:16

    Topics: Borohydrides; Chemistry Techniques, Synthetic; Glycosylation; Lamivudine; Thiophenes

2017
ROS activated prodrug for ALDH overexpressed cancer stem cells.
    Chemical communications (Cambridge, England), 2021, Dec-21, Volume: 58, Issue:1

    Topics: Aldehyde Dehydrogenase; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Neoplastic Stem Cells; Prodrugs; Reactive Oxygen Species; Thiophenes

2021