Compounds > 1,3-ditolylguanidine
Page last updated: 2024-08-18

1,3-ditolylguanidine and u-50488

1,3-ditolylguanidine has been researched along with u-50488 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Weigl, M; Wünsch, B1
Englberger, W; Geiger, C; Lehmkuhl, K; Schepmann, D; Wünsch, B; Zelenka, C1
Rack, E; Schepmann, D; Sunnam, SK; Wünsch, B1
Amata, E; Dichiara, M; Fortuna, S; Mamolo, MG; Marrazzo, A; Pasquinucci, L; Romano, M; Turnaturi, R; Zampieri, D1
Fang, H; Helmeste, DM; Li, M; Tang, SW1
Kameyama, T; Mori, E; Ukai, M1

Other Studies

6 other study(ies) available for 1,3-ditolylguanidine and u-50488

ArticleYear
Synthesis of bridged piperazines with sigma receptor affinity.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:10

    Topics: Cross-Linking Reagents; Molecular Structure; Piperazine; Piperazines; Receptors, sigma

2007
Conformationally constrained kappa receptor agonists: stereoselective synthesis and pharmacological evaluation of 6,8-diazabicyclo[3.2.2]nonane derivatives.
    Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10

    Topics: Animals; Azabicyclo Compounds; Cell Line; Guinea Pigs; Humans; In Vitro Techniques; Molecular Conformation; Radioligand Assay; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship

2010
Synthesis of 7,9-diazabicyclo[4.2.2]decanes as conformationally restricted κ receptor agonists: fine tuning of the dihedral angle of the ethylenediamine pharmacophore.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Animals; Azabicyclo Compounds; Ethylenediamines; Guinea Pigs; Ligands; Models, Molecular; Molecular Structure; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship

2011
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands.
    Bioorganic & medicinal chemistry letters, 2022, 09-15, Volume: 72

    Topics: Haloperidol; Ligands; Piperidines; Quinolines; Receptors, sigma; Structure-Activity Relationship

2022
Multiple [3H]-nemonapride binding sites in calf brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Benzamides; Binding, Competitive; Brain; Cattle; Cerebellum; Cerebral Cortex; Corpus Striatum; Dioxanes; Dopamine Agonists; Dopamine Antagonists; Guanidines; Haloperidol; In Vitro Techniques; Isotope Labeling; Narcotic Antagonists; Pentazocine; Piperidines; Propylamines; Pyrrolidines; Receptors, Dopamine D2; Receptors, sigma; Sulpiride; Tritium

1997
Modulatory effects of morphine, U-50488H and 1,3-di-(2-tolyl)guanidine on cocaine-like discriminative stimulus in the rat using two-choice discrete-trial avoidance paradigm.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:8

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Animals; Avoidance Learning; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Guanidines; Male; Morphine; Rats; Receptors, Opioid

1997