1,3-ditolylguanidine has been researched along with n-methylaspartate in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 21 (95.45) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Addae, JI; Connick, JH; Nicholson, CD; Stone, TW | 1 |
| Blier, P; de Montigny, C; Debonnel, G; Monnet, FP | 1 |
| de Montigny, C; Debonnel, G; Fournier, A; Monnet, FP | 1 |
| Brent, PJ | 1 |
| Dragunow, M; Faull, RL; Jansen, K; Robertson, GS; Robertson, HA | 1 |
| Boksa, P; Chaudieu, I; Mount, H; Quirion, R | 1 |
| Kesingland, AC; Singh, L; Tricklebank, MD; Wong, EH | 1 |
| De Montigny, C; Debonnel, G; Junien, JL; Monnet, FP | 1 |
| Chavkin, C; Malouf, AT; Swearengen, E | 1 |
| Larson, AA; Sun, X | 1 |
| Baulieu, EE; Mahé, V; Monnet, FP; Robel, P | 1 |
| Bergeron, R; de Montigny, C; Debonnel, G; Gronier, B; Monnet, FP | 1 |
| Abdel-Hamid, K; Church, J; Fletcher, EJ; MacDonald, JF | 1 |
| de Montigny, C; Debonnel, G; Monnet, FP | 1 |
| Bergeron, R; de Montigny, C; Debonnel, G | 2 |
| Bergeron, R; De Montigny, C; Debonnel, G; Monnet, FP | 1 |
| Hornfeldt, CS; Kitto, KF; Larson, AA | 1 |
| Bowen, WD; de Costa, BR; Monnet, FP | 1 |
| Bergeron, R; Debonnel, G | 1 |
| Hayashi, T; Kagaya, A; Nishida, A; Shimizu, M; Su, TP; Yamawaki, S | 1 |
| Debonnel, G; Gronier, B | 1 |
22 other study(ies) available for 1,3-ditolylguanidine and n-methylaspartate
| Article | Year |
|---|---|
The sigma ligand 1,3-di-o-tolylguanidine depresses amino acid-induced excitation non-selectively in rat brain.
Topics: Action Potentials; Animals; Brain; Cerebral Cortex; Guanidines; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Receptors, Opioid; Receptors, sigma | 1992 |
Modulation by sigma ligands of N-methyl-D-aspartate-induced [3H]noradrenaline release in the rat hippocampus: G-protein dependency.
Topics: Animals; Calcium; Cinnamates; Cyclopropanes; Dose-Response Relationship, Drug; Ethylmaleimide; GTP-Binding Proteins; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Norepinephrine; Pertussis Toxin; Piperidines; Rats; Rats, Inbred Strains; Spiperone; Tritium; Virulence Factors, Bordetella | 1992 |
Neuropeptide Y potentiates the N-methyl-D-aspartate response in the CA3 dorsal hippocampus. II. Involvement of a subtype of sigma receptor.
Topics: Animals; Cinnamates; Cyclopropanes; Drug Synergism; Guanidines; Haloperidol; Hippocampus; Male; N-Methylaspartate; Neuropeptide Y; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Receptors, sigma; Spiperone | 1992 |
Similar behavioural effects of sigma agonists and PCP-like non-competitive NMDA antagonists in guinea-pigs.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzamides; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Guanidines; Guinea Pigs; Haloperidol; Ketamine; Male; Motor Activity; N-Methylaspartate; Pentazocine; Phenazocine; Phencyclidine; Quinpirole; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Remoxipride | 1991 |
D2 dopamine receptor antagonists induce fos and related proteins in rat striatal neurons.
Topics: Animals; Benzamides; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Guanidines; Haloperidol; Male; N-Methylaspartate; Neurons; Oncogene Proteins v-fos; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma | 1990 |
Phencyclidine and related compounds evoked [3H]dopamine release from rat mesencephalic cell cultures by a mechanism independent of the phencyclidine receptor, sigma binding site, or dopamine uptake site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Binding Sites; Cells, Cultured; Dioxolanes; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Guanidines; Mesencephalon; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Phencyclidine; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Sigma Factor; Tritium | 1990 |
Evidence against an involvement of the haloperidol-sensitive sigma recognition site in the discriminative stimulus properties of (+)-N-allylnormetazocine ((+)-SKF 10,047).
Topics: Animals; Aspartic Acid; Binding, Competitive; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Guanidines; Haloperidol; Male; Mice; N-Methylaspartate; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures | 1990 |
N-methyl-D-aspartate-induced neuronal activation is selectively modulated by sigma receptors.
Topics: Animals; Aspartic Acid; Guanidines; Haloperidol; In Vitro Techniques; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Spiperone | 1990 |
Comparison of the actions of phencyclidine and sigma ligands on CA1 hippocampal pyramidal neurons in the rat.
Topics: Action Potentials; Animals; Aspartic Acid; Guanidines; Hippocampus; Male; N-Methylaspartate; Neurons; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma | 1988 |
Regulation of sigma activity by the amino-terminus of substance P in the mouse spinal cord: involvement of phencyclidine (PCP) sites not linked to N-methyl-D-aspartate (NMDA) activity.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Drug Synergism; Guanidines; Haloperidol; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Receptors, sigma; Spinal Cord; Substance P; Up-Regulation | 1993 |
Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Female; Guanidines; Haloperidol; Hippocampus; Kinetics; N-Methylaspartate; Norepinephrine; Ovariectomy; Pertussis Toxin; Piperazines; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Stereotaxic Techniques; Virulence Factors, Bordetella | 1995 |
The effects of sigma ligands and of neuropeptide Y on N-methyl-D-aspartate-induced neuronal activation of CA3 dorsal hippocampus neurones are differentially affected by pertussin toxin.
Topics: Animals; Anticonvulsants; Cinnamates; Cyclopropanes; Drug Synergism; GTP-Binding Proteins; Guanidines; Haloperidol; Hippocampus; Ligands; Male; N-Methylaspartate; Neurons; Neuropeptide Y; Pentazocine; Pertussis Toxin; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, sigma; Virulence Factors, Bordetella | 1994 |
Selective reduction of N-methyl-D-aspartate-evoked responses by 1,3-di(2-tolyl)guanidine in mouse and rat cultured hippocampal pyramidal neurones.
Topics: Amino Acids; Animals; Anticonvulsants; Binding, Competitive; Calcium; Cells, Cultured; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; Fura-2; Guanidines; Hippocampus; Mice; N-Methylaspartate; Neurons; Pregnancy; Pyramidal Tracts; Rats; Rats, Wistar; Receptors, sigma; Spectrometry, Fluorescence | 1993 |
The cytochromes P-450 are not involved in the modulation of the N-methyl-D-aspartate response by sigma ligands in the rat CA3 dorsal hippocampus.
Topics: Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophysiology; Guanidines; Hippocampus; Iontophoresis; Ligands; Male; N-Methylaspartate; Neurons; Paralysis; Phenobarbital; Proadifen; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, sigma; Zoxazolamine | 1993 |
Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors.
Topics: Animals; Anisoles; Dehydroepiandrosterone; Drug Synergism; Female; Guanidines; Haloperidol; Hippocampus; Iontophoresis; Ligands; Male; N-Methylaspartate; Pertussis Toxin; Pregnenolone; Progesterone; Propylamines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Spiperone; Virulence Factors, Bordetella | 1996 |
Differential effects of sigma ligands on the N-methyl-D-aspartate response in the CA1 and CA3 regions of the dorsal hippocampus: effect of mossy fiber lesioning.
Topics: Acetylcholine; Animals; Anticonvulsants; Cinnamates; Colchicine; Cyclopropanes; Electrophysiology; Guanidines; Hippocampus; Male; N-Methylaspartate; Nerve Fibers; Neuropeptide Y; Neurotoxins; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1996 |
Evidence that the NH2-terminus of substance P modulates N-methyl-D-aspartate-induced activity by an action involving sigma receptors.
Topics: Analysis of Variance; Animals; Anticonvulsants; Antipsychotic Agents; Behavior, Animal; Drug Therapy, Combination; Excitatory Amino Acid Agonists; Guanidines; Haloperidol; Male; Mice; N-Methylaspartate; Receptors, sigma; Substance P | 1996 |
Differentiation of sigma ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slices.
Topics: Animals; Anisoles; Anticonvulsants; Antipsychotic Agents; Cyclohexylamines; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Ligands; Male; N-Methylaspartate; Narcotics; Norepinephrine; Pentazocine; Propylamines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Tritium | 1996 |
Effects of low and high doses of selective sigma ligands: further evidence suggesting the existence of different subtypes of sigma receptors.
Topics: Animals; Cinnamates; Cyclohexylamines; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Excitatory Amino Acid Agonists; Guanidines; Hippocampus; Ligands; Male; N-Methylaspartate; Neurons; Pentazocine; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma | 1997 |
Effect of short-term and long-term treatments with sigma ligands on the N-methyl-D-aspartate response in the CA3 region of the rat dorsal hippocampus.
Topics: Animals; Cinnamates; Cyclopropanes; Guanidines; Haloperidol; Hippocampus; Male; N-Methylaspartate; Pentazocine; Rats; Rats, Sprague-Dawley; Receptors, sigma | 1997 |
Neuroleptics with differential affinities at dopamine D2 receptors and sigma receptors affect differently the N-methyl-D-aspartate-induced increase in intracellular calcium concentration: involvement of protein kinase.
Topics: Animals; Antipsychotic Agents; Calcium; Cells, Cultured; Chlorpromazine; Clozapine; Dopamine Antagonists; Frontal Lobe; Guanidines; Haloperidol; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, sigma; Sulpiride | 1999 |
Involvement of sigma receptors in the modulation of the glutamatergic/NMDA neurotransmission in the dopaminergic systems.
Topics: Analgesics, Opioid; Animals; Caudate Nucleus; Cinnamates; Cyclopropanes; Dopamine; Electrophysiology; Excitatory Amino Acids; Glutamic Acid; Guanidines; Kainic Acid; Male; N-Methylaspartate; Neurons; Nucleus Accumbens; Pentazocine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, sigma; Sigma-1 Receptor; Spiro Compounds; Substantia Nigra; Synaptic Transmission; Thiazoles; Ventral Tegmental Area | 1999 |